自社株取引日	役員・従業員名	役員・従業員の役職	株式の種類	売却／購入	株数	株価
2018-03-31	LIDDY, EDWARD M	Director	普通株式	購入	330	$94.65
2018-03-31	ALPERN, ROBERT J	Director	普通株式	購入	69	$94.65
2018-03-16	GONZALEZ, RICHARD A	Director, Chairman of the Board and CEO	普通株式	購入	2,115	$0.00
2018-03-16	GONZALEZ, RICHARD A	Director, Chairman of the Board and CEO	普通株式	売却	5,722	$0.00
2018-03-01	CHASE, WILLIAM J	EVP, Chief Financial Officer	普通株式	売却	32,400	$114.50
2018-03-01	ALBAN, CARLOS	EVP, Commercial Operations	普通株式	売却	14,829	$114.43
2018-03-01	ALBAN, CARLOS	EVP, Commercial Operations	普通株式	売却	48,100	$0.00
2018-03-01	ALBAN, CARLOS	EVP, Commercial Operations	普通株式	購入	48,100	$29.23
2018-03-01	ALBAN, CARLOS	EVP, Commercial Operations	普通株式	売却	19,169	$113.75
2018-03-01	ALBAN, CARLOS	EVP, Commercial Operations	普通株式	売却	46,997	$114.63
2018-03-01	CHASE, WILLIAM J	EVP, Chief Financial Officer	普通株式	売却	13,400	$0.00
2018-03-01	CHASE, WILLIAM J	EVP, Chief Financial Officer	普通株式	売却	19,000	$0.00
2018-03-01	CHASE, WILLIAM J	EVP, Chief Financial Officer	普通株式	購入	13,400	$28.31
2018-03-01	SCHUMACHER, LAURA J	Executive Vice President	普通株式	売却	25,000	$117.85
2018-03-01	CHASE, WILLIAM J	EVP, Chief Financial Officer	普通株式	購入	19,000	$24.21
2018-02-28	SEVERINO, MICHAEL	EVP, R&D and CSO	普通株式	売却	27,683	$118.26
2018-02-28	SALEKI-GERHARDT, AZITA	SVP, Operations	普通株式	売却	1,337	$117.77
2018-02-28	CHASE, WILLIAM J	EVP, Chief Financial Officer	普通株式	売却	38,528	$119.44