APLS
アペリス・ファーマシューティカルズ・インク
Apellis Pharmaceuticals Inc
株価・概要
$40.87
0.03 (0.0612%)
06:00AM 2026/04/17 (JST)
NASDAQ | USD
52週間レンジ
16.1
40.79
昨夜レンジ
40.80
40.90
前日終値
$40.85
出来高（数量）
6,291,489
ベータ値
-0.197
50日移動平均値
$23.73
200日移動平均値
$23.32
1株あたりの利益（EPS）
0.18
予想PER（株価収益率）
46.3
配当金
$None
配当利回り
0%
インサイダー保有率
13.737%
機関投資家保有率
90.918%
APLS - 会社概要
アペリス・ファーマシューティカルズ社は、マサチューセッツ州ウォルサムに拠点を置く革新的な臨床段階のバイオ医薬品企業であり、自己免疫疾患や炎症性疾患の治療のために補体系を標的とした画期的な治療法の開発を専門としています。主力の開発資産を含む強力なパイプラインを有し、未だ満たされていない医療ニーズを抱える複雑な疾患に苦しむ患者の治療パラダイムを変革することを目指しています。補体阻害の科学を推進することに尽力し、アペリスはバイオ医薬品業界の再構築と医療課題への有効なソリューションの提供において重要な役割を果たすことが期待されています。
本社住所
100 FIFTH AVENUE, WALTHAM, MA, UNITED STATES, 02451
企業サイト
https://apellis.com
会計年度終了
December
最新四半期
2025-12-31
利益・成長性
1株あたりの利益（EPS）
$0.18
希薄化後1株当たり利益EPS（直近12ヶ月）
$0.18
四半期利益成長率（前年比）
0.0%
四半期売上成長率（前年比）
-5.9%
アナリスト予想・評価
目標株価
$39.93
強気
2
買い
5
ホールド
13
売り
0
弱気
0
EPS（1株当たり純利益）
| 7日前 | 30日前 | 60日前 | 90日前 | 予想レンジ | |||
|---|---|---|---|---|---|---|---|
配当履歴
| 権利落ち日 | 配当宣言日 | 権利確定日 | 配当金支払日 | 配当金額 |
|---|
株式分割
| 効力発生日 | 分割比率 |
|---|
インサイダーの売却・購入履歴
| 自社株取引日 | 役員・従業員名 | 役員・従業員の役職 | 株式の種類 | 売却／購入 | 株数 | 株価 |
|---|---|---|---|---|---|---|
| 2026-03-11 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 64,869 | $0.00 |
| 2026-03-11 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 64,869 | $0.00 |
| 2026-02-27 | DOLSTEN, MIKAEL | Director | ストックオプション | 購入 | 24,135 | $20.96 |
| 2026-02-27 | DOLSTEN, MIKAEL | Director | 普通株式 | 購入 | 14,312 | $0.00 |
| 2026-02-11 | DELONG, MARK JEFFREY | Chief Business & Strat Officer | 普通株式 | 売却 | 368 | $22.15 |
| 2026-02-03 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 売却 | 8,840 | $0.00 |
| 2026-02-03 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 8,840 | $3.76 |
| 2026-01-28 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 25,840 | $0.00 |
| 2026-01-28 | BOUCHER, KELLEY | Chief People Officer | 普通株式 | 購入 | 30,146 | $0.00 |
| 2026-01-28 | CHOPAS, JAMES GEORGE | VP/Chief Accounting Officer | 普通株式 | 購入 | 16,150 | $0.00 |
| 2026-01-28 | DELONG, MARK JEFFREY | Chief Business & Strat Officer | 普通株式 | 購入 | 36,606 | $0.00 |
| 2026-01-28 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 195,952 | $0.00 |
| 2026-01-28 | WATSON, DAVID O. | General Counsel | 普通株式 | 購入 | 55,986 | $0.00 |
| 2026-01-28 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 購入 | 58,140 | $0.00 |
| 2026-01-28 | NICHOLSON, NUR | Chief Technical Officer | 普通株式 | 購入 | 45,220 | $0.00 |
| 2026-01-28 | MELTZER, LESLIE | Chief Research and Development | 普通株式 | 購入 | 45,220 | $0.00 |
| 2026-01-22 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 売却 | 10,287 | $21.77 |
| 2026-01-22 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 7,832 | $21.77 |
| 2026-01-22 | BAUMAL, CAROLINE | Chief Medical Officer | 普通株式 | 売却 | 2,797 | $21.77 |
| 2026-01-22 | CHOPAS, JAMES GEORGE | VP/Chief Accounting Officer | 普通株式 | 売却 | 2,064 | $21.77 |
| 2026-01-22 | DELONG, MARK JEFFREY | Chief Business & Strat Officer | 普通株式 | 売却 | 3,371 | $21.77 |
| 2026-01-22 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 5,928 | $21.77 |
| 2026-01-22 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 27,192 | $21.77 |
| 2026-01-22 | NICHOLSON, NUR | Chief Technical Officer | 普通株式 | 売却 | 7,725 | $21.77 |
| 2026-01-20 | NICHOLSON, NUR | Chief Technical Officer | 普通株式 | 売却 | 2,203 | $19.79 |
| 2026-01-20 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 2,475 | $19.79 |
| 2026-01-20 | BAUMAL, CAROLINE | Chief Medical Officer | 普通株式 | 売却 | 1,882 | $19.79 |
| 2026-01-20 | CHOPAS, JAMES GEORGE | VP/Chief Accounting Officer | 普通株式 | 売却 | 726 | $19.79 |
| 2026-01-20 | DELONG, MARK JEFFREY | Chief Business & Strat Officer | 普通株式 | 売却 | 1,334 | $19.79 |
| 2026-01-20 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 909 | $19.79 |
| 2026-01-20 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 8,182 | $19.79 |
| 2026-01-20 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 売却 | 2,892 | $19.79 |
| 2026-01-13 | NICHOLSON, NUR | Chief Technical Officer | 普通株式 | 売却 | 2,618 | $22.19 |
| 2026-01-13 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 5,780 | $22.19 |
| 2026-01-13 | CHOPAS, JAMES GEORGE | VP/Chief Accounting Officer | 普通株式 | 売却 | 873 | $22.19 |
| 2026-01-13 | DELONG, MARK JEFFREY | Chief Business & Strat Officer | 普通株式 | 売却 | 1,780 | $22.19 |
| 2026-01-13 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 2,277 | $22.19 |
| 2026-01-13 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 10,186 | $22.19 |
| 2026-01-13 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 売却 | 3,856 | $22.19 |
| 2026-01-07 | WATSON, DAVID O. | General Counsel | 普通株式 | 購入 | 888 | $14.95 |
| 2026-01-07 | WATSON, DAVID O. | General Counsel | ストックオプション | 売却 | 888 | $0.00 |
| 2026-01-05 | BAUMAL, CAROLINE | Chief Medical Officer | 普通株式 | 売却 | 3,020 | $25.53 |
| 2026-01-01 | CHAN, GERALD | Director | ストックオプション | 購入 | 14,684 | $0.00 |
| 2026-01-01 | WHEELER, CRAIG A | Director | ストックオプション | 購入 | 14,684 | $0.00 |
| 2026-01-01 | WHEELER, CRAIG A | Director | 普通株式 | 購入 | 7,961 | $0.00 |
| 2026-01-01 | WALBERT, KELI | Director | ストックオプション | 購入 | 14,684 | $0.00 |
| 2026-01-01 | WALBERT, KELI | Director | 普通株式 | 購入 | 7,961 | $0.00 |
| 2026-01-01 | FONTEYNE, PAUL R. | Director | ストックオプション | 購入 | 14,684 | $0.00 |
| 2026-01-01 | FONTEYNE, PAUL R. | Director | 普通株式 | 購入 | 7,961 | $0.00 |
| 2026-01-01 | O'BRIEN, STEPHANIE MONAGHAN | Director | ストックオプション | 購入 | 14,684 | $0.00 |
| 2026-01-01 | O'BRIEN, STEPHANIE MONAGHAN | Director | 普通株式 | 購入 | 7,961 | $0.00 |
| 2026-01-01 | CHAN, GERALD | Director | 普通株式 | 購入 | 7,961 | $0.00 |
| 2026-01-01 | DUNLOP, A. SINCLAIR | Director | ストックオプション | 購入 | 14,684 | $0.00 |
| 2026-01-01 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 購入 | 7,961 | $0.00 |
| 2026-01-01 | MACHIELS, ALEC | Director | ストックオプション | 購入 | 14,684 | $0.00 |
| 2026-01-01 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 7,961 | $0.00 |
| 2025-12-16 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 5,000 | $24.49 |
| 2025-11-17 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 5,000 | $20.06 |
| 2025-10-21 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 売却 | 10,000 | $28.03 |
| 2025-10-21 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 購入 | 10,000 | $10.03 |
| 2025-10-21 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | ストックオプション | 売却 | 10,000 | $0.00 |
| 2025-10-16 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 5,000 | $25.22 |
| 2025-10-10 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 3,837 | $0.00 |
| 2025-10-10 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 31,092 | $23.72 |
| 2025-09-30 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 31,092 | $22.58 |
| 2025-09-30 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 3,837 | $0.00 |
| 2025-09-19 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 3,837 | $0.00 |
| 2025-09-19 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 31,092 | $22.95 |
| 2025-09-16 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 5,000 | $24.34 |
| 2025-09-15 | CHOPAS, JAMES GEORGE | VP/Chief Accounting Officer | 普通株式 | 売却 | 189 | $24.19 |
| 2025-09-10 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 20,000 | $26.17 |
| 2025-09-08 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 売却 | 10,000 | $27.83 |
| 2025-09-08 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 売却 | 32,729 | $27.86 |
| 2025-09-08 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 購入 | 15,000 | $10.03 |
| 2025-09-08 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | ストックオプション | 売却 | 15,000 | $0.00 |
| 2025-09-02 | CHOPAS, JAMES GEORGE | VP/Chief Accounting Officer | 普通株式 | 売却 | 548 | $28.08 |
| 2025-09-02 | BOUCHER, KELLEY | Chief People Officer | 普通株式 | 購入 | 30,476 | $0.00 |
| 2025-09-02 | BOUCHER, KELLEY | Chief People Officer | ストックオプション | 購入 | 45,766 | $0.00 |
| 2025-08-28 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 49,963 | $28.39 |
| 2025-08-27 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 175,037 | $28.19 |
| 2025-08-26 | MELTZER, LESLIE | Chief Research and Development | 普通株式 | 購入 | 61,804 | $0.00 |
| 2025-08-26 | MELTZER, LESLIE | Chief Research and Development | ストックオプション | 購入 | 92,592 | $0.00 |
| 2025-08-18 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 5,000 | $27.80 |
| 2025-07-17 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 売却 | 8,997 | $0.00 |
| 2025-07-17 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 8,997 | $4.31 |
| 2025-07-17 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 19,725 | $20.21 |
| 2025-07-16 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 5,000 | $19.55 |
| 2025-07-15 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 1,900 | $20.09 |
| 2025-07-15 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 売却 | 800 | $0.00 |
| 2025-07-15 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 800 | $4.31 |
| 2025-07-14 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 売却 | 65,203 | $0.00 |
| 2025-07-14 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 137,465 | $20.19 |
| 2025-07-14 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 65,203 | $4.31 |
| 2025-06-24 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 4,787 | $0.00 |
| 2025-06-18 | CHOPAS, JAMES GEORGE | VP/Chief Accounting Officer | 普通株式 | 購入 | 6,250 | $0.00 |
| 2025-06-16 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 5,000 | $18.77 |
| 2025-06-09 | BAUMAL, CAROLINE | Chief Medical Officer | ストックオプション | 購入 | 82,500 | $19.39 |
| 2025-06-09 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 購入 | 82,500 | $19.39 |
| 2025-06-09 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | ストックオプション | 購入 | 82,500 | $19.39 |
| 2025-06-09 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 購入 | 287,500 | $19.39 |
| 2025-06-09 | NICHOLSON, NUR | Chief Technical Officer | ストックオプション | 購入 | 82,500 | $19.39 |
| 2025-06-09 | BOUCHER, KELLEY | Chief People Officer | 普通株式 | 購入 | 45,095 | $0.00 |
| 2025-06-09 | DELONG, MARK JEFFREY | Chief Business & Strat Officer | ストックオプション | 購入 | 82,500 | $19.39 |
| 2025-06-09 | CHOPAS, JAMES GEORGE | VP/Chief Accounting Officer | ストックオプション | 購入 | 11,250 | $19.39 |
| 2025-06-09 | WATSON, DAVID O. | General Counsel | ストックオプション | 購入 | 82,500 | $19.39 |
| 2025-06-09 | BOUCHER, KELLEY | Chief People Officer | ストックオプション | 購入 | 67,396 | $19.39 |
| 2025-05-28 | BOUCHER, KELLEY | Chief People Officer | 普通株式 | 購入 | 22,087 | $0.00 |
| 2025-05-28 | BOUCHER, KELLEY | Chief People Officer | ストックオプション | 購入 | 32,976 | $16.80 |
| 2025-05-21 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 売却 | 12,780 | $0.00 |
| 2025-05-21 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 12,780 | $3.76 |
| 2025-04-17 | WHEELER, CRAIG A | Director | 普通株式 | 購入 | 16,483 | $0.00 |
| 2025-04-17 | WHEELER, CRAIG A | Director | ストックオプション | 購入 | 28,195 | $18.20 |
| 2025-03-17 | CHOPAS, JAMES GEORGE | VP/Chief Accounting Officer | 普通株式 | 売却 | 183 | $24.82 |
| 2025-03-05 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 5,569 | $25.10 |
| 2025-03-04 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 6,667 | $0.00 |
| 2025-03-04 | WATSON, DAVID O. | General Counsel | 普通株式 | 購入 | 6,667 | $0.00 |
| 2025-02-11 | DELONG, MARK JEFFREY | Chief Business & Strat Officer | 普通株式 | 売却 | 363 | $28.54 |
| 2025-01-29 | LEWIS, KAREN | Chief People Officer | 普通株式 | 売却 | 364 | $29.52 |
| 2025-01-29 | EISELE, JEFFREY | Chief Development Officer | 普通株式 | 売却 | 278 | $29.52 |
| 2025-01-29 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 826 | $29.52 |
| 2025-01-29 | NICHOLSON, NUR | Chief Technical Officer | 普通株式 | 売却 | 825 | $29.52 |
| 2025-01-29 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 695 | $29.52 |
| 2025-01-29 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 売却 | 695 | $29.52 |
| 2025-01-29 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 2,824 | $29.52 |
| 2025-01-29 | DELONG, MARK JEFFREY | Chief Business & Strat Officer | 普通株式 | 売却 | 365 | $29.52 |
| 2025-01-29 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 売却 | 546 | $29.52 |
| 2025-01-22 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 13,551 | $30.43 |
| 2025-01-22 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 売却 | 3,323 | $30.43 |
| 2025-01-22 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 売却 | 3,088 | $30.43 |
| 2025-01-22 | NICHOLSON, NUR | Chief Technical Officer | 普通株式 | 売却 | 3,948 | $30.43 |
| 2025-01-22 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 3,323 | $30.43 |
| 2025-01-22 | LEWIS, KAREN | Chief People Officer | 普通株式 | 売却 | 1,751 | $30.43 |
| 2025-01-22 | EISELE, JEFFREY | Chief Development Officer | 普通株式 | 売却 | 1,291 | $30.43 |
| 2025-01-22 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 3,948 | $30.43 |
| 2025-01-22 | DELONG, MARK JEFFREY | Chief Business & Strat Officer | 普通株式 | 売却 | 1,396 | $30.43 |
| 2025-01-22 | CHOPAS, JAMES GEORGE | VP/Chief Accounting Officer | 普通株式 | 売却 | 1,096 | $30.43 |
| 2025-01-21 | LEWIS, KAREN | Chief People Officer | 普通株式 | 購入 | 28,508 | $0.00 |
| 2025-01-21 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 130,662 | $0.00 |
| 2025-01-21 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 15,045 | $0.00 |
| 2025-01-21 | NICHOLSON, NUR | Chief Technical Officer | 普通株式 | 購入 | 36,426 | $0.00 |
| 2025-01-21 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 購入 | 45,929 | $0.00 |
| 2025-01-21 | DELONG, MARK JEFFREY | Chief Business & Strat Officer | 普通株式 | 購入 | 28,508 | $0.00 |
| 2025-01-21 | WATSON, DAVID O. | General Counsel | 普通株式 | 購入 | 42,762 | $0.00 |
| 2025-01-21 | CHOPAS, JAMES GEORGE | VP/Chief Accounting Officer | 普通株式 | 購入 | 12,591 | $0.00 |
| 2025-01-21 | BAUMAL, CAROLINE | Chief Medical Officer | 普通株式 | 購入 | 39,594 | $0.00 |
| 2025-01-17 | LEWIS, KAREN | Chief People Officer | 普通株式 | 売却 | 1,241 | $29.96 |
| 2025-01-17 | BAUMAL, CAROLINE | Chief Medical Officer | 普通株式 | 売却 | 1,853 | $29.96 |
| 2025-01-17 | CHOPAS, JAMES GEORGE | VP/Chief Accounting Officer | 普通株式 | 売却 | 715 | $29.96 |
| 2025-01-17 | DELONG, MARK JEFFREY | Chief Business & Strat Officer | 普通株式 | 売却 | 1,235 | $29.96 |
| 2025-01-17 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 750 | $29.96 |
| 2025-01-17 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 6,007 | $29.96 |
| 2025-01-17 | NICHOLSON, NUR | Chief Technical Officer | 普通株式 | 売却 | 2,145 | $29.96 |
| 2025-01-17 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 売却 | 1,730 | $29.96 |
| 2025-01-17 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 売却 | 2,201 | $29.96 |
| 2025-01-17 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 2,201 | $29.96 |
| 2025-01-13 | LEWIS, KAREN | Chief People Officer | 普通株式 | 売却 | 1,599 | $28.70 |
| 2025-01-13 | EISELE, JEFFREY | Chief Development Officer | 普通株式 | 売却 | 264 | $28.70 |
| 2025-01-13 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 売却 | 2,685 | $28.70 |
| 2025-01-13 | CHOPAS, JAMES GEORGE | VP/Chief Accounting Officer | 普通株式 | 売却 | 783 | $28.70 |
| 2025-01-13 | NICHOLSON, NUR | Chief Technical Officer | 普通株式 | 売却 | 2,632 | $28.70 |
| 2025-01-13 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 売却 | 2,170 | $28.70 |
| 2025-01-13 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 4,965 | $28.70 |
| 2025-01-13 | DELONG, MARK JEFFREY | Chief Business & Strat Officer | 普通株式 | 売却 | 1,599 | $28.70 |
| 2025-01-13 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 2,288 | $28.70 |
| 2025-01-13 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 6,247 | $28.70 |
| 2025-01-08 | WALBERT, KELI | Director | 普通株式 | 購入 | 9,090 | $0.00 |
| 2025-01-08 | WALBERT, KELI | Director | ストックオプション | 購入 | 15,388 | $33.00 |
| 2025-01-06 | BAUMAL, CAROLINE | Chief Medical Officer | 普通株式 | 売却 | 2,816 | $33.81 |
| 2025-01-01 | CHAN, GERALD | Director | ストックオプション | 購入 | 11,199 | $0.00 |
| 2025-01-01 | CHAN, GERALD | Director | 普通株式 | 購入 | 6,267 | $0.00 |
| 2025-01-01 | DUNLOP, A. SINCLAIR | Director | ストックオプション | 購入 | 11,199 | $0.00 |
| 2025-01-01 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 購入 | 6,267 | $0.00 |
| 2025-01-01 | FONTEYNE, PAUL R. | Director | ストックオプション | 購入 | 11,199 | $0.00 |
| 2025-01-01 | FONTEYNE, PAUL R. | Director | 普通株式 | 購入 | 6,267 | $0.00 |
| 2025-01-01 | MACHIELS, ALEC | Director | ストックオプション | 購入 | 11,199 | $0.00 |
| 2025-01-01 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 6,267 | $0.00 |
| 2025-01-01 | O'BRIEN, STEPHANIE MONAGHAN | Director | ストックオプション | 購入 | 11,199 | $0.00 |
| 2025-01-01 | O'BRIEN, STEPHANIE MONAGHAN | Director | 普通株式 | 購入 | 6,267 | $0.00 |
| 2024-12-31 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | ストックオプション | 売却 | 1,042 | $0.00 |
| 2024-12-31 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 購入 | 1,042 | $14.95 |
| 2024-12-31 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | ストックオプション | 売却 | 10,054 | $0.00 |
| 2024-12-31 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 購入 | 10,054 | $13.85 |
| 2024-12-23 | EISELE, JEFFREY | Chief Development Officer | 普通株式 | 売却 | 63 | $33.09 |
| 2024-12-11 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 5,000 | $34.24 |
| 2024-11-01 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 182,146 | $0.00 |
| 2024-09-27 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 10,569 | $0.00 |
| 2024-09-27 | WATSON, DAVID O. | General Counsel | 普通株式 | 購入 | 10,569 | $0.00 |
| 2024-09-23 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 購入 | 4,600 | $13.19 |
| 2024-09-23 | DUNLOP, A. SINCLAIR | Director | ストックオプション | 売却 | 4,600 | $0.00 |
| 2024-09-16 | CHOPAS, JAMES GEORGE | VP/Chief Accounting Officer | 普通株式 | 売却 | 192 | $36.21 |
| 2024-09-16 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 29,476 | $36.09 |
| 2024-09-16 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 7,524 | $36.79 |
| 2024-09-03 | CHOPAS, JAMES GEORGE | VP/Chief Accounting Officer | 普通株式 | 売却 | 550 | $39.49 |
| 2024-08-12 | DELONG, MARK JEFFREY | Chief Business & Strat Officer | ストックオプション | 売却 | 5,201 | $0.00 |
| 2024-08-12 | DELONG, MARK JEFFREY | Chief Business & Strat Officer | 普通株式 | 購入 | 5,201 | $13.85 |
| 2024-06-28 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 購入 | 900 | $13.19 |
| 2024-06-28 | DUNLOP, A. SINCLAIR | Director | ストックオプション | 売却 | 900 | $0.00 |
| 2024-06-21 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 35,305 | $39.22 |
| 2024-06-21 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 1,695 | $39.63 |
| 2024-05-20 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 売却 | 24,500 | $0.00 |
| 2024-05-20 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 24,500 | $3.76 |
| 2024-05-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 売却 | 78,907 | $0.00 |
| 2024-05-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 100 | $44.03 |
| 2024-05-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 22,472 | $42.85 |
| 2024-05-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 56,335 | $42.15 |
| 2024-05-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 78,907 | $4.31 |
| 2024-04-18 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 売却 | 14,164 | $0.00 |
| 2024-04-18 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 購入 | 14,164 | $0.00 |
| 2024-04-12 | DUNLOP, A. SINCLAIR | Director | ストックオプション | 売却 | 1,500 | $0.00 |
| 2024-04-12 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 購入 | 1,500 | $13.19 |
| 2024-04-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 売却 | 69,107 | $0.00 |
| 2024-04-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 4,728 | $54.92 |
| 2024-04-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 64,379 | $54.12 |
| 2024-04-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 69,107 | $3.76 |
| 2024-04-01 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 購入 | 4,000 | $10.03 |
| 2024-04-01 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 売却 | 4,000 | $58.66 |
| 2024-04-01 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | ストックオプション | 売却 | 4,000 | $0.00 |
| 2024-03-19 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 18,681 | $57.18 |
| 2024-03-18 | DELONG, MARK JEFFREY | Chief Business & Strat Officer | 普通株式 | 売却 | 9,913 | $56.90 |
| 2024-03-15 | CHOPAS, JAMES GEORGE | VP/Chief Accounting Officer | 普通株式 | 売却 | 184 | $56.46 |
| 2024-03-13 | NICHOLSON, NUR | Chief Technical Officer | 普通株式 | 売却 | 3,452 | $58.13 |
| 2024-03-13 | NICHOLSON, NUR | Chief Technical Officer | 普通株式 | 売却 | 7,768 | $57.31 |
| 2024-03-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 売却 | 69,107 | $0.00 |
| 2024-03-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 100 | $63.35 |
| 2024-03-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 26,257 | $62.69 |
| 2024-03-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 42,750 | $61.88 |
| 2024-03-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 69,107 | $3.67 |
| 2024-03-06 | WATSON, DAVID O. | General Counsel | 普通株式 | 購入 | 3,762 | $13.85 |
| 2024-03-06 | WATSON, DAVID O. | General Counsel | ストックオプション | 売却 | 3,762 | $0.00 |
| 2024-03-01 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 62,503 | $64.26 |
| 2024-03-01 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 売却 | 50,000 | $0.00 |
| 2024-03-01 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 売却 | 200,000 | $0.00 |
| 2024-03-01 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 購入 | 6,000 | $10.03 |
| 2024-03-01 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 売却 | 4,000 | $62.86 |
| 2024-03-01 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 売却 | 2,000 | $63.95 |
| 2024-03-01 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | ストックオプション | 売却 | 6,000 | $0.00 |
| 2024-03-01 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 50,000 | $3.76 |
| 2024-03-01 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 200,000 | $4.31 |
| 2024-03-01 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 28,868 | $62.21 |
| 2024-03-01 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 41,704 | $62.96 |
| 2024-03-01 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 116,512 | $64.92 |
| 2024-03-01 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 413 | $65.68 |
| 2024-02-12 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 売却 | 1,431 | $67.77 |
| 2024-02-12 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 1,148 | $67.77 |
| 2024-02-12 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 3,962 | $67.77 |
| 2024-02-12 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 売却 | 1,148 | $67.77 |
| 2024-02-12 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 781 | $67.77 |
| 2024-02-12 | DELONG, MARK JEFFREY | Chief Business & Strat Officer | 普通株式 | 売却 | 597 | $67.77 |
| 2024-01-30 | EISELE, JEFFREY | Chief Development Officer | 普通株式 | 売却 | 971 | $65.53 |
| 2024-01-30 | LEWIS, KAREN | Chief People Officer | 普通株式 | 売却 | 883 | $65.53 |
| 2024-01-29 | EISELE, JEFFREY | Chief Development Officer | 普通株式 | 売却 | 279 | $64.14 |
| 2024-01-29 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 2,843 | $64.14 |
| 2024-01-29 | DELONG, MARK JEFFREY | Chief Business & Strat Officer | 普通株式 | 売却 | 367 | $64.14 |
| 2024-01-29 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 874 | $64.14 |
| 2024-01-29 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 906 | $64.14 |
| 2024-01-29 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 売却 | 906 | $64.14 |
| 2024-01-29 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 売却 | 906 | $64.14 |
| 2024-01-29 | NICHOLSON, NUR | Chief Technical Officer | 普通株式 | 売却 | 835 | $64.14 |
| 2024-01-29 | LEWIS, KAREN | Chief People Officer | 普通株式 | 売却 | 367 | $64.14 |
| 2024-01-23 | EISELE, JEFFREY | Chief Development Officer | 普通株式 | 売却 | 7,378 | $63.69 |
| 2024-01-23 | LEWIS, KAREN | Chief People Officer | 普通株式 | 売却 | 4,286 | $63.69 |
| 2024-01-22 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 13,431 | $65.00 |
| 2024-01-22 | EISELE, JEFFREY | Chief Development Officer | 普通株式 | 売却 | 1,607 | $65.00 |
| 2024-01-22 | DELONG, MARK JEFFREY | Chief Business & Strat Officer | 普通株式 | 売却 | 1,384 | $65.00 |
| 2024-01-22 | CHOPAS, JAMES GEORGE | VP/Chief Accounting Officer | 普通株式 | 売却 | 1,061 | $65.00 |
| 2024-01-22 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 4,184 | $65.00 |
| 2024-01-22 | LEWIS, KAREN | Chief People Officer | 普通株式 | 売却 | 1,738 | $65.00 |
| 2024-01-22 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 3,913 | $65.00 |
| 2024-01-22 | NICHOLSON, NUR | Chief Technical Officer | 普通株式 | 売却 | 2,593 | $65.00 |
| 2024-01-22 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 売却 | 3,551 | $65.00 |
| 2024-01-22 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 売却 | 3,413 | $65.00 |
| 2024-01-17 | EISELE, JEFFREY | Chief Development Officer | 普通株式 | 売却 | 5,207 | $65.58 |
| 2024-01-17 | LEWIS, KAREN | Chief People Officer | 普通株式 | 売却 | 3,276 | $65.58 |
| 2024-01-16 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 4,240 | $66.81 |
| 2024-01-16 | WATSON, DAVID O. | General Counsel | ストックオプション | 購入 | 34,533 | $66.30 |
| 2024-01-16 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 購入 | 23,748 | $0.00 |
| 2024-01-16 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 売却 | 2,235 | $66.81 |
| 2024-01-16 | TOWNSEND, ADAM J. | Chief Commercial Officer | ストックオプション | 購入 | 34,533 | $66.30 |
| 2024-01-16 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 購入 | 23,748 | $0.00 |
| 2024-01-16 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 売却 | 2,235 | $66.81 |
| 2024-01-16 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | ストックオプション | 購入 | 34,533 | $66.30 |
| 2024-01-16 | BAUMAL, CAROLINE | Chief Medical Officer | 普通株式 | 購入 | 25,445 | $0.00 |
| 2024-01-16 | BAUMAL, CAROLINE | Chief Medical Officer | ストックオプション | 購入 | 37,000 | $66.30 |
| 2024-01-16 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 72,094 | $0.00 |
| 2024-01-16 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 7,851 | $66.81 |
| 2024-01-16 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 購入 | 104,834 | $66.30 |
| 2024-01-16 | EISELE, JEFFREY | Chief Development Officer | 普通株式 | 購入 | 19,508 | $0.00 |
| 2024-01-16 | EISELE, JEFFREY | Chief Development Officer | 普通株式 | 売却 | 438 | $66.81 |
| 2024-01-16 | EISELE, JEFFREY | Chief Development Officer | ストックオプション | 購入 | 28,367 | $66.30 |
| 2024-01-16 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 6,743 | $0.00 |
| 2024-01-16 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 1,632 | $66.81 |
| 2024-01-16 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 購入 | 9,805 | $66.30 |
| 2024-01-16 | CHOPAS, JAMES GEORGE | VP/Chief Accounting Officer | 普通株式 | 購入 | 8,312 | $0.00 |
| 2024-01-16 | CHOPAS, JAMES GEORGE | VP/Chief Accounting Officer | 普通株式 | 売却 | 864 | $66.81 |
| 2024-01-16 | CHOPAS, JAMES GEORGE | VP/Chief Accounting Officer | ストックオプション | 購入 | 12,086 | $66.30 |
| 2024-01-16 | LEWIS, KAREN | Chief People Officer | 普通株式 | 購入 | 16,963 | $0.00 |
| 2024-01-16 | LEWIS, KAREN | Chief People Officer | 普通株式 | 売却 | 1,632 | $66.81 |
| 2024-01-16 | LEWIS, KAREN | Chief People Officer | ストックオプション | 購入 | 24,666 | $66.30 |
| 2024-01-16 | NICHOLSON, NUR | Chief Technical Officer | ストックオプション | 購入 | 28,367 | $66.30 |
| 2024-01-16 | NICHOLSON, NUR | Chief Technical Officer | 普通株式 | 売却 | 1,857 | $66.81 |
| 2024-01-16 | NICHOLSON, NUR | Chief Technical Officer | 普通株式 | 購入 | 19,508 | $0.00 |
| 2024-01-16 | DELONG, MARK JEFFREY | Chief Business & Strat Officer | ストックオプション | 購入 | 24,666 | $66.30 |
| 2024-01-16 | DELONG, MARK JEFFREY | Chief Business & Strat Officer | 普通株式 | 売却 | 1,631 | $66.81 |
| 2024-01-16 | DELONG, MARK JEFFREY | Chief Business & Strat Officer | 普通株式 | 購入 | 16,963 | $0.00 |
| 2024-01-16 | WATSON, DAVID O. | General Counsel | 普通株式 | 購入 | 23,748 | $0.00 |
| 2024-01-04 | BAUMAL, CAROLINE | Chief Medical Officer | 普通株式 | 売却 | 2,751 | $60.05 |
| 2024-01-01 | O'BRIEN, STEPHANIE MONAGHAN | Director | ストックオプション | 購入 | 5,748 | $59.86 |
| 2024-01-01 | O'BRIEN, STEPHANIE MONAGHAN | Director | 普通株式 | 購入 | 3,341 | $0.00 |
| 2024-01-01 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 購入 | 3,341 | $0.00 |
| 2024-01-01 | DUNLOP, A. SINCLAIR | Director | ストックオプション | 購入 | 5,748 | $59.86 |
| 2024-01-01 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 3,341 | $0.00 |
| 2024-01-01 | MACHIELS, ALEC | Director | ストックオプション | 購入 | 5,748 | $59.86 |
| 2024-01-01 | FONTEYNE, PAUL R. | Director | ストックオプション | 購入 | 5,748 | $59.86 |
| 2024-01-01 | CHAN, GERALD | Director | 普通株式 | 購入 | 3,341 | $0.00 |
| 2024-01-01 | FONTEYNE, PAUL R. | Director | 普通株式 | 購入 | 3,341 | $0.00 |
| 2024-01-01 | CHAN, GERALD | Director | ストックオプション | 購入 | 5,748 | $59.86 |
| 2023-12-27 | EISELE, JEFFREY | Chief Development Officer | 普通株式 | 売却 | 235 | $60.23 |
| 2023-12-26 | EISELE, JEFFREY | Chief Development Officer | 普通株式 | 売却 | 68 | $57.86 |
| 2023-12-19 | WATSON, DAVID O. | General Counsel | ストックオプション | 売却 | 7,905 | $0.00 |
| 2023-12-19 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 1,605 | $57.00 |
| 2023-12-19 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 2,300 | $57.38 |
| 2023-12-19 | WATSON, DAVID O. | General Counsel | 普通株式 | 購入 | 7,905 | $13.85 |
| 2023-12-14 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 購入 | 6,274 | $13.19 |
| 2023-12-14 | DUNLOP, A. SINCLAIR | Director | ストックオプション | 売却 | 6,274 | $0.00 |
| 2023-12-01 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 24,000 | $61.14 |
| 2023-12-01 | SCHEIBLER, LUKAS | Chief Research Officer | 普通株式 | 購入 | 10,000 | $13.85 |
| 2023-12-01 | SCHEIBLER, LUKAS | Chief Research Officer | 普通株式 | 売却 | 10,000 | $60.00 |
| 2023-12-01 | SCHEIBLER, LUKAS | Chief Research Officer | ストックオプション | 売却 | 10,000 | $0.00 |
| 2023-12-01 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 購入 | 110,000 | $15.09 |
| 2023-12-01 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 売却 | 67,557 | $60.50 |
| 2023-12-01 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 売却 | 42,443 | $61.31 |
| 2023-12-01 | TOWNSEND, ADAM J. | Chief Commercial Officer | ストックオプション | 売却 | 110,000 | $0.00 |
| 2023-11-30 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 売却 | 300 | $54.79 |
| 2023-11-30 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 売却 | 13,858 | $54.73 |
| 2023-11-30 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 購入 | 14,158 | $10.03 |
| 2023-11-30 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | ストックオプション | 売却 | 14,158 | $0.00 |
| 2023-11-21 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $48.80 |
| 2023-11-17 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 1,250 | $2.67 |
| 2023-11-17 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 8,894 | $49.99 |
| 2023-11-17 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 1,250 | $47.74 |
| 2023-11-17 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 1,250 | $0.00 |
| 2023-11-14 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 45,000 | $3.76 |
| 2023-11-14 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 売却 | 45,000 | $0.00 |
| 2023-11-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 12,000 | $47.27 |
| 2023-11-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 売却 | 17,494 | $0.00 |
| 2023-11-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 17,494 | $2.67 |
| 2023-10-23 | CHOPAS, JAMES GEORGE | VP/Chief Accounting Officer | 普通株式 | 売却 | 132 | $46.04 |
| 2023-10-23 | DELONG, MARK JEFFREY | Chief Business & Strat Officer | 普通株式 | 売却 | 131 | $46.04 |
| 2023-10-17 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 24,000 | $49.00 |
| 2023-10-17 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 1,250 | $2.67 |
| 2023-10-17 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 1,250 | $0.00 |
| 2023-10-17 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 1,250 | $48.50 |
| 2023-10-09 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 18,500 | $2.67 |
| 2023-10-09 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 12,000 | $40.38 |
| 2023-10-09 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 売却 | 18,500 | $0.00 |
| 2023-09-19 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 150,000 | $0.00 |
| 2023-09-19 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 150,000 | $0.00 |
| 2023-09-18 | NICHOLSON, NUR | Chief Technical Officer | ストックオプション | 売却 | 9,719 | $0.00 |
| 2023-09-18 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 1,250 | $2.67 |
| 2023-09-18 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 1,250 | $45.00 |
| 2023-09-18 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 1,250 | $0.00 |
| 2023-09-18 | NICHOLSON, NUR | Chief Technical Officer | 普通株式 | 購入 | 9,719 | $29.76 |
| 2023-09-18 | NICHOLSON, NUR | Chief Technical Officer | 普通株式 | 売却 | 9,719 | $42.21 |
| 2023-09-18 | NICHOLSON, NUR | Chief Technical Officer | 普通株式 | 売却 | 10,631 | $46.15 |
| 2023-09-15 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 1,250 | $0.00 |
| 2023-09-15 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 1,250 | $2.67 |
| 2023-09-15 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 1,250 | $45.34 |
| 2023-09-14 | CHOPAS, JAMES GEORGE | VP/Chief Accounting Officer | 普通株式 | 購入 | 2,500 | $0.00 |
| 2023-09-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 売却 | 18,500 | $0.00 |
| 2023-09-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 18,500 | $2.67 |
| 2023-09-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 12,000 | $42.87 |
| 2023-09-06 | SCHEIBLER, LUKAS | Chief Research Officer | 普通株式 | 売却 | 1,756 | $43.01 |
| 2023-09-01 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 売却 | 300,000 | $0.00 |
| 2023-09-01 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 139,716 | $41.70 |
| 2023-09-01 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 300,000 | $2.67 |
| 2023-09-01 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 10,284 | $42.44 |
| 2023-08-31 | CHOPAS, JAMES GEORGE | VP/Chief Accounting Officer | 普通株式 | 売却 | 551 | $41.23 |
| 2023-08-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 18,500 | $2.67 |
| 2023-08-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 売却 | 18,500 | $0.00 |
| 2023-08-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 12,000 | $23.66 |
| 2023-07-21 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 49,779 | $2.67 |
| 2023-07-21 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 49,779 | $0.00 |
| 2023-07-20 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 50,000 | $0.00 |
| 2023-07-20 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 50,000 | $2.67 |
| 2023-07-17 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 1,250 | $0.00 |
| 2023-07-17 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 1,250 | $64.79 |
| 2023-07-17 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 1,250 | $2.67 |
| 2023-07-10 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 12,000 | $84.55 |
| 2023-07-10 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 売却 | 18,500 | $0.00 |
| 2023-07-10 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 18,500 | $2.67 |
| 2023-07-03 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 売却 | 3,287 | $90.42 |
| 2023-07-03 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 購入 | 6,779 | $10.03 |
| 2023-07-03 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 売却 | 3,192 | $89.41 |
| 2023-07-03 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 売却 | 300 | $91.10 |
| 2023-07-03 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | ストックオプション | 売却 | 6,779 | $0.00 |
| 2023-07-03 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 8,510 | $89.98 |
| 2023-06-28 | WATSON, DAVID O. | General Counsel | 普通株式 | 購入 | 12,750 | $0.00 |
| 2023-06-28 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 12,750 | $0.00 |
| 2023-06-20 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 1,250 | $2.67 |
| 2023-06-20 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 1,250 | $0.00 |
| 2023-06-20 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 1,250 | $88.41 |
| 2023-06-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 売却 | 18,500 | $0.00 |
| 2023-06-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 18,500 | $2.67 |
| 2023-06-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 12,000 | $91.35 |
| 2023-06-05 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | ストックオプション | 売却 | 69,779 | $0.00 |
| 2023-06-05 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 売却 | 1,600 | $90.60 |
| 2023-06-05 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 売却 | 30,609 | $87.79 |
| 2023-06-05 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 売却 | 7,064 | $88.36 |
| 2023-06-05 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 売却 | 30,506 | $89.83 |
| 2023-06-05 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 購入 | 69,779 | $10.03 |
| 2023-06-01 | LEWIS, KAREN | Chief People Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2023-06-01 | LEWIS, KAREN | Chief People Officer | 普通株式 | 売却 | 5,000 | $86.00 |
| 2023-06-01 | LEWIS, KAREN | Chief People Officer | 普通株式 | 購入 | 5,000 | $34.11 |
| 2023-05-24 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 20,000 | $0.00 |
| 2023-05-24 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 20,000 | $0.00 |
| 2023-05-17 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 1,250 | $0.00 |
| 2023-05-17 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 1,250 | $2.67 |
| 2023-05-17 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 売却 | 20,000 | $0.00 |
| 2023-05-17 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 20,000 | $2.67 |
| 2023-05-17 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 1,250 | $88.66 |
| 2023-05-16 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 売却 | 30,000 | $0.00 |
| 2023-05-16 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 30,000 | $2.67 |
| 2023-05-16 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 934 | $83.17 |
| 2023-05-16 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 1,800 | $83.85 |
| 2023-05-16 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 3,007 | $85.90 |
| 2023-05-16 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 7,528 | $87.02 |
| 2023-05-16 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 2,120 | $87.67 |
| 2023-05-16 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 14,611 | $85.01 |
| 2023-05-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 売却 | 18,500 | $0.00 |
| 2023-05-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 18,500 | $2.67 |
| 2023-05-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 12,000 | $92.39 |
| 2023-05-03 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 売却 | 20,000 | $0.00 |
| 2023-05-03 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 購入 | 5,000 | $15.09 |
| 2023-05-03 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 売却 | 5,000 | $82.71 |
| 2023-05-03 | TOWNSEND, ADAM J. | Chief Commercial Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2023-05-03 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 購入 | 20,000 | $0.00 |
| 2023-04-27 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 382,946 | $0.00 |
| 2023-04-27 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 382,946 | $0.00 |
| 2023-04-21 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 67,955 | $0.00 |
| 2023-04-21 | WATSON, DAVID O. | General Counsel | 普通株式 | 購入 | 67,955 | $0.00 |
| 2023-04-19 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 購入 | 36,232 | $0.00 |
| 2023-04-19 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 20,000 | $2.67 |
| 2023-04-19 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 売却 | 36,232 | $0.00 |
| 2023-04-19 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 売却 | 20,000 | $0.00 |
| 2023-04-18 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 30,000 | $82.02 |
| 2023-04-18 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 30,000 | $2.67 |
| 2023-04-18 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 売却 | 30,000 | $0.00 |
| 2023-04-17 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 1,250 | $81.05 |
| 2023-04-17 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 1,250 | $0.00 |
| 2023-04-17 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 1,250 | $2.67 |
| 2023-04-10 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 売却 | 18,500 | $0.00 |
| 2023-04-10 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 12,000 | $78.21 |
| 2023-04-10 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 18,500 | $2.67 |
| 2023-04-05 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 26,990 | $0.00 |
| 2023-04-05 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 26,990 | $0.00 |
| 2023-04-04 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 380,000 | $0.00 |
| 2023-04-04 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 380,000 | $0.00 |
| 2023-04-03 | LEWIS, KAREN | Chief People Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2023-04-03 | LEWIS, KAREN | Chief People Officer | 普通株式 | 売却 | 5,000 | $75.00 |
| 2023-04-03 | LEWIS, KAREN | Chief People Officer | 普通株式 | 購入 | 5,000 | $34.11 |
| 2023-04-03 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 500 | $74.05 |
| 2023-04-03 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 227,221 | $0.00 |
| 2023-04-03 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 227,221 | $0.00 |
| 2023-04-03 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 売却 | 5,000 | $74.05 |
| 2023-04-03 | TOWNSEND, ADAM J. | Chief Commercial Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2023-04-03 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 購入 | 5,000 | $15.09 |
| 2023-03-22 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 100,000 | $3.76 |
| 2023-03-22 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 20,000 | $2.67 |
| 2023-03-22 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 7,221 | $13.85 |
| 2023-03-22 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 売却 | 20,000 | $0.00 |
| 2023-03-22 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 売却 | 100,000 | $0.00 |
| 2023-03-22 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 売却 | 7,221 | $0.00 |
| 2023-03-21 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 売却 | 30,000 | $0.00 |
| 2023-03-21 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 30,000 | $62.74 |
| 2023-03-21 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 30,000 | $2.67 |
| 2023-03-17 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 1,250 | $64.03 |
| 2023-03-17 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 1,250 | $2.67 |
| 2023-03-17 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 1,250 | $0.00 |
| 2023-03-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 売却 | 18,500 | $0.00 |
| 2023-03-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 12,000 | $63.79 |
| 2023-03-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 18,500 | $2.67 |
| 2023-03-03 | TOWNSEND, ADAM J. | Chief Commercial Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2023-03-03 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 購入 | 5,000 | $15.09 |
| 2023-03-03 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 売却 | 5,000 | $63.84 |
| 2023-03-01 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 500 | $65.33 |
| 2023-02-27 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 売却 | 100,000 | $0.00 |
| 2023-02-27 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 100,000 | $3.76 |
| 2023-02-23 | EISELE, JEFFREY | Chief Development Officer | 普通株式 | 売却 | 1,646 | $68.76 |
| 2023-02-23 | LEWIS, KAREN | Chief People Officer | 普通株式 | 売却 | 1,104 | $68.76 |
| 2023-02-21 | CHOPAS, JAMES GEORGE | VP/Chief Accounting Officer | 普通株式 | 購入 | 4,044 | $0.00 |
| 2023-02-21 | NICHOLSON, NUR | Chief Technical Officer | ストックオプション | 購入 | 14,023 | $0.00 |
| 2023-02-21 | NICHOLSON, NUR | Chief Technical Officer | 普通株式 | 売却 | 825 | $58.50 |
| 2023-02-21 | NICHOLSON, NUR | Chief Technical Officer | 普通株式 | 購入 | 9,886 | $0.00 |
| 2023-02-21 | EISELE, JEFFREY | Chief Development Officer | ストックオプション | 購入 | 14,023 | $0.00 |
| 2023-02-21 | EISELE, JEFFREY | Chief Development Officer | 普通株式 | 売却 | 825 | $58.50 |
| 2023-02-21 | EISELE, JEFFREY | Chief Development Officer | 普通株式 | 購入 | 9,886 | $0.00 |
| 2023-02-21 | DELONG, MARK JEFFREY | Chief Business & Strat Officer | ストックオプション | 購入 | 7,489 | $0.00 |
| 2023-02-21 | DELONG, MARK JEFFREY | Chief Business & Strat Officer | 普通株式 | 売却 | 441 | $58.50 |
| 2023-02-21 | DELONG, MARK JEFFREY | Chief Business & Strat Officer | 普通株式 | 購入 | 5,280 | $0.00 |
| 2023-02-21 | SCHEIBLER, LUKAS | Chief Research Officer | ストックオプション | 購入 | 14,023 | $0.00 |
| 2023-02-21 | SCHEIBLER, LUKAS | Chief Research Officer | 普通株式 | 売却 | 715 | $58.50 |
| 2023-02-21 | SCHEIBLER, LUKAS | Chief Research Officer | 普通株式 | 購入 | 9,886 | $0.00 |
| 2023-02-21 | LEWIS, KAREN | Chief People Officer | 普通株式 | 売却 | 553 | $58.50 |
| 2023-02-21 | LEWIS, KAREN | Chief People Officer | ストックオプション | 購入 | 9,402 | $0.00 |
| 2023-02-21 | TOWNSEND, ADAM J. | Chief Commercial Officer | ストックオプション | 購入 | 14,023 | $0.00 |
| 2023-02-21 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 売却 | 1,041 | $58.50 |
| 2023-02-21 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 購入 | 9,886 | $0.00 |
| 2023-02-21 | FRANCOIS, CEDRIC | Chief Executive Officer | ストックオプション | 購入 | 19,728 | $0.00 |
| 2023-02-21 | FRANCOIS, CEDRIC | Chief Executive Officer | 普通株式 | 売却 | 1,602 | $58.50 |
| 2023-02-21 | FRANCOIS, CEDRIC | Chief Executive Officer | 普通株式 | 購入 | 13,908 | $0.00 |
| 2023-02-21 | WATSON, DAVID O. | General Counsel | ストックオプション | 購入 | 14,023 | $0.00 |
| 2023-02-21 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 825 | $58.50 |
| 2023-02-21 | WATSON, DAVID O. | General Counsel | 普通株式 | 購入 | 9,886 | $0.00 |
| 2023-02-21 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | ストックオプション | 購入 | 16,572 | $0.00 |
| 2023-02-21 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 売却 | 974 | $58.50 |
| 2023-02-21 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 購入 | 11,683 | $0.00 |
| 2023-02-21 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 1,195 | $58.50 |
| 2023-02-21 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 9,886 | $0.00 |
| 2023-02-21 | CHOPAS, JAMES GEORGE | VP/Chief Accounting Officer | ストックオプション | 購入 | 5,737 | $0.00 |
| 2023-02-21 | CHOPAS, JAMES GEORGE | VP/Chief Accounting Officer | 普通株式 | 売却 | 334 | $58.50 |
| 2023-02-21 | LEWIS, KAREN | Chief People Officer | 普通株式 | 購入 | 6,628 | $0.00 |
| 2023-02-21 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 購入 | 14,023 | $0.00 |
| 2023-02-17 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 1,250 | $2.67 |
| 2023-02-17 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 1,250 | $52.38 |
| 2023-02-17 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 1,250 | $0.00 |
| 2023-02-10 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 3,958 | $51.21 |
| 2023-02-10 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 売却 | 782 | $51.21 |
| 2023-02-10 | SCHEIBLER, LUKAS | Chief Research Officer | 普通株式 | 売却 | 678 | $51.21 |
| 2023-02-10 | DELONG, MARK JEFFREY | Chief Business & Strat Officer | 普通株式 | 売却 | 670 | $51.21 |
| 2023-02-10 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 1,134 | $51.21 |
| 2023-02-10 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 532 | $51.21 |
| 2023-02-10 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 売却 | 975 | $51.21 |
| 2023-02-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 売却 | 18,500 | $0.00 |
| 2023-02-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 12,000 | $54.45 |
| 2023-02-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 18,500 | $2.67 |
| 2023-02-03 | TOWNSEND, ADAM J. | Chief Commercial Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2023-02-03 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 購入 | 5,000 | $15.09 |
| 2023-02-03 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 売却 | 5,000 | $55.85 |
| 2023-02-01 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 500 | $52.61 |
| 2023-01-30 | EISELE, JEFFREY | Chief Development Officer | 普通株式 | 売却 | 883 | $52.76 |
| 2023-01-30 | LEWIS, KAREN | Chief People Officer | 普通株式 | 売却 | 883 | $52.76 |
| 2023-01-27 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 2,879 | $52.77 |
| 2023-01-27 | EISELE, JEFFREY | Chief Development Officer | 普通株式 | 売却 | 367 | $52.77 |
| 2023-01-27 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 832 | $52.77 |
| 2023-01-27 | DELONG, MARK JEFFREY | Chief Business & Strat Officer | 普通株式 | 売却 | 367 | $52.77 |
| 2023-01-27 | LEWIS, KAREN | Chief People Officer | 普通株式 | 売却 | 367 | $52.77 |
| 2023-01-27 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 551 | $52.77 |
| 2023-01-27 | NICHOLSON, NUR | Chief Technical Officer | 普通株式 | 売却 | 551 | $52.77 |
| 2023-01-27 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 売却 | 551 | $52.77 |
| 2023-01-27 | SCHEIBLER, LUKAS | Chief Research Officer | 普通株式 | 売却 | 542 | $52.77 |
| 2023-01-27 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 売却 | 551 | $52.77 |
| 2023-01-23 | EISELE, JEFFREY | Chief Development Officer | 普通株式 | 売却 | 4,479 | $51.58 |
| 2023-01-23 | LEWIS, KAREN | Chief People Officer | 普通株式 | 売却 | 2,955 | $51.58 |
| 2023-01-20 | DELONG, MARK JEFFREY | Chief Business & Strat Officer | 普通株式 | 売却 | 1,149 | $52.05 |
| 2023-01-20 | BROWN, VICTORIA L. | Program Team Lead | 普通株式 | 売却 | 1,412 | $52.05 |
| 2023-01-20 | EISELE, JEFFREY | Chief Development Officer | 普通株式 | 売却 | 2,033 | $52.05 |
| 2023-01-20 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 2,326 | $52.05 |
| 2023-01-20 | CHOPAS, JAMES GEORGE | VP/Chief Accounting Officer | 普通株式 | 売却 | 919 | $52.05 |
| 2023-01-20 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 2,034 | $52.05 |
| 2023-01-20 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 売却 | 1,912 | $52.05 |
| 2023-01-20 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 売却 | 2,379 | $52.05 |
| 2023-01-20 | SCHEIBLER, LUKAS | Chief Research Officer | 普通株式 | 売却 | 2,015 | $52.05 |
| 2023-01-20 | NICHOLSON, NUR | Chief Technical Officer | 普通株式 | 売却 | 2,034 | $52.05 |
| 2023-01-20 | LEWIS, KAREN | Chief People Officer | 普通株式 | 売却 | 1,411 | $52.05 |
| 2023-01-20 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 9,453 | $52.05 |
| 2023-01-17 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 1,250 | $2.67 |
| 2023-01-17 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 1,250 | $52.42 |
| 2023-01-17 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 1,250 | $0.00 |
| 2023-01-12 | SCHEIBLER, LUKAS | Chief Research Officer | ストックオプション | 購入 | 35,472 | $52.66 |
| 2023-01-12 | CHOPAS, JAMES GEORGE | VP/Chief Accounting Officer | ストックオプション | 購入 | 15,114 | $52.66 |
| 2023-01-12 | CHOPAS, JAMES GEORGE | VP/Chief Accounting Officer | 普通株式 | 購入 | 9,621 | $0.00 |
| 2023-01-12 | DELONG, MARK JEFFREY | Chief Business & Strat Officer | ストックオプション | 購入 | 30,845 | $52.66 |
| 2023-01-12 | DELONG, MARK JEFFREY | Chief Business & Strat Officer | 普通株式 | 購入 | 19,634 | $0.00 |
| 2023-01-12 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 購入 | 30,845 | $52.66 |
| 2023-01-12 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 19,634 | $0.00 |
| 2023-01-12 | EISELE, JEFFREY | Chief Development Officer | ストックオプション | 購入 | 35,472 | $52.66 |
| 2023-01-12 | EISELE, JEFFREY | Chief Development Officer | 普通株式 | 購入 | 22,580 | $0.00 |
| 2023-01-12 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 購入 | 131,093 | $52.66 |
| 2023-01-12 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 83,447 | $0.00 |
| 2023-01-12 | LEWIS, KAREN | Chief People Officer | ストックオプション | 購入 | 30,845 | $52.66 |
| 2023-01-12 | LEWIS, KAREN | Chief People Officer | 普通株式 | 購入 | 19,634 | $0.00 |
| 2023-01-12 | NICHOLSON, NUR | Chief Technical Officer | ストックオプション | 購入 | 35,472 | $52.66 |
| 2023-01-12 | NICHOLSON, NUR | Chief Technical Officer | 普通株式 | 購入 | 22,580 | $0.00 |
| 2023-01-12 | TOWNSEND, ADAM J. | Chief Commercial Officer | ストックオプション | 購入 | 43,183 | $52.66 |
| 2023-01-12 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 購入 | 27,488 | $0.00 |
| 2023-01-12 | SCHEIBLER, LUKAS | Chief Research Officer | 普通株式 | 購入 | 22,580 | $0.00 |
| 2023-01-12 | WATSON, DAVID O. | General Counsel | ストックオプション | 購入 | 37,708 | $52.66 |
| 2023-01-12 | WATSON, DAVID O. | General Counsel | 普通株式 | 購入 | 29,452 | $0.00 |
| 2023-01-12 | WATSON, DAVID O. | General Counsel | 普通株式 | 購入 | 24,003 | $0.00 |
| 2023-01-12 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | ストックオプション | 購入 | 43,183 | $52.66 |
| 2023-01-12 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 購入 | 27,488 | $0.00 |
| 2023-01-09 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 12,000 | $46.08 |
| 2023-01-09 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 18,500 | $2.67 |
| 2023-01-09 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 売却 | 18,500 | $0.00 |
| 2023-01-05 | GROSSI, FEDERICO | Chief Medical Officer | 普通株式 | 売却 | 2,500 | $48.79 |
| 2023-01-03 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 500 | $50.70 |
| 2023-01-03 | BAUMAL, CAROLINE | Chief Medical Officer | ストックオプション | 購入 | 49,000 | $50.28 |
| 2023-01-03 | TOWNSEND, ADAM J. | Chief Commercial Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2023-01-03 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 売却 | 5,000 | $50.70 |
| 2023-01-03 | BAUMAL, CAROLINE | Chief Medical Officer | 普通株式 | 購入 | 35,549 | $0.00 |
| 2023-01-03 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 購入 | 5,000 | $15.09 |
| 2023-01-01 | CHAN, GERALD | Director | ストックオプション | 購入 | 7,441 | $0.00 |
| 2023-01-01 | FONTEYNE, PAUL R. | Director | ストックオプション | 購入 | 7,441 | $0.00 |
| 2023-01-01 | DUNLOP, A. SINCLAIR | Director | ストックオプション | 購入 | 7,441 | $0.00 |
| 2023-01-01 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 3,867 | $0.00 |
| 2023-01-01 | MACHIELS, ALEC | Director | ストックオプション | 購入 | 7,441 | $0.00 |
| 2023-01-01 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 購入 | 3,867 | $0.00 |
| 2023-01-01 | O'BRIEN, STEPHANIE MONAGHAN | Director | 普通株式 | 購入 | 3,867 | $0.00 |
| 2023-01-01 | O'BRIEN, STEPHANIE MONAGHAN | Director | ストックオプション | 購入 | 7,441 | $0.00 |
| 2023-01-01 | CHAN, GERALD | Director | 普通株式 | 購入 | 3,867 | $0.00 |
| 2023-01-01 | FONTEYNE, PAUL R. | Director | 普通株式 | 購入 | 3,867 | $0.00 |
| 2022-12-29 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 7,000 | $3.67 |
| 2022-12-29 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 売却 | 7,000 | $0.00 |
| 2022-12-22 | EISELE, JEFFREY | Exec VP, Program Team Lead | 普通株式 | 売却 | 89 | $51.68 |
| 2022-12-19 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 15,000 | $3.76 |
| 2022-12-19 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 売却 | 6,688 | $0.00 |
| 2022-12-19 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 売却 | 15,000 | $0.00 |
| 2022-12-19 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 売却 | 28,200 | $0.00 |
| 2022-12-19 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 24,449 | $52.07 |
| 2022-12-19 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 3,751 | $51.97 |
| 2022-12-19 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 6,688 | $14.95 |
| 2022-12-19 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 28,200 | $2.67 |
| 2022-12-15 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 1,250 | $2.67 |
| 2022-12-15 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 1,250 | $0.00 |
| 2022-12-15 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 1,250 | $52.35 |
| 2022-12-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 18,500 | $2.67 |
| 2022-12-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 売却 | 18,500 | $0.00 |
| 2022-12-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 12,000 | $47.50 |
| 2022-12-05 | TOWNSEND, ADAM J. | Chief Commercial Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2022-12-05 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 売却 | 5,000 | $50.38 |
| 2022-12-05 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 売却 | 5,000 | $15.09 |
| 2022-12-01 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 500 | $49.93 |
| 2022-12-01 | GROSSI, FEDERICO | Chief Medical Officer | 普通株式 | 売却 | 2,500 | $49.93 |
| 2022-11-15 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 1,250 | $0.00 |
| 2022-11-15 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 1,250 | $2.67 |
| 2022-11-15 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 1,250 | $48.01 |
| 2022-11-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 12,000 | $46.47 |
| 2022-11-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 18,500 | $2.67 |
| 2022-11-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 売却 | 18,500 | $0.00 |
| 2022-11-03 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 売却 | 5,000 | $15.09 |
| 2022-11-03 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 売却 | 5,000 | $58.54 |
| 2022-11-03 | TOWNSEND, ADAM J. | Chief Commercial Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2022-11-01 | GROSSI, FEDERICO | Chief Medical Officer | 普通株式 | 売却 | 2,500 | $60.83 |
| 2022-11-01 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 500 | $60.83 |
| 2022-10-26 | BROWN, VICTORIA L. | Program Team Lead | 普通株式 | 売却 | 130 | $58.41 |
| 2022-10-20 | CHOPAS, JAMES GEORGE | VP/Chief Accounting Officer | 普通株式 | 売却 | 130 | $58.00 |
| 2022-10-20 | DELONG, MARK JEFFREY | Senior Vice President | 普通株式 | 売却 | 196 | $58.00 |
| 2022-10-14 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 1,250 | $0.00 |
| 2022-10-14 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 1,250 | $2.67 |
| 2022-10-14 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 1,250 | $59.31 |
| 2022-10-10 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 12,000 | $57.50 |
| 2022-10-10 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 18,500 | $2.67 |
| 2022-10-10 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 売却 | 18,500 | $0.00 |
| 2022-10-03 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 2,500 | $66.69 |
| 2022-10-03 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 購入 | 5,000 | $15.09 |
| 2022-10-03 | TOWNSEND, ADAM J. | Chief Commercial Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2022-10-03 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 売却 | 5,000 | $66.69 |
| 2022-09-15 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 1,250 | $0.00 |
| 2022-09-15 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 1,250 | $66.00 |
| 2022-09-15 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 1,250 | $2.67 |
| 2022-09-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 12,000 | $63.98 |
| 2022-09-08 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 15,000 | $65.00 |
| 2022-09-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 18,500 | $2.67 |
| 2022-09-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 売却 | 18,500 | $0.00 |
| 2022-09-06 | TOWNSEND, ADAM J. | Chief Commercial Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2022-09-06 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 売却 | 5,000 | $60.38 |
| 2022-09-06 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 購入 | 5,000 | $15.09 |
| 2022-09-01 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 2,500 | $60.30 |
| 2022-08-30 | CHOPAS, JAMES GEORGE | VP/Chief Accounting Officer | 普通株式 | 売却 | 558 | $58.84 |
| 2022-08-25 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 購入 | 4,306 | $13.19 |
| 2022-08-25 | DUNLOP, A. SINCLAIR | Director | ストックオプション | 売却 | 4,306 | $0.00 |
| 2022-08-17 | DELONG, MARK JEFFREY | Senior Vice President | 普通株式 | 購入 | 5,000 | $15.52 |
| 2022-08-17 | DELONG, MARK JEFFREY | Senior Vice President | ストックオプション | 売却 | 5,000 | $0.00 |
| 2022-08-17 | DELONG, MARK JEFFREY | Senior Vice President | 普通株式 | 売却 | 5,000 | $69.50 |
| 2022-08-16 | DUNLOP, A. SINCLAIR | Director | ストックオプション | 売却 | 25,394 | $0.00 |
| 2022-08-16 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 購入 | 25,394 | $14.00 |
| 2022-08-15 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 1,250 | $2.67 |
| 2022-08-15 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 購入 | 12,500 | $15.09 |
| 2022-08-15 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 1,250 | $0.00 |
| 2022-08-15 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 1,250 | $67.21 |
| 2022-08-15 | TOWNSEND, ADAM J. | Chief Commercial Officer | ストックオプション | 売却 | 12,500 | $0.00 |
| 2022-08-15 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 売却 | 12,500 | $69.00 |
| 2022-08-11 | DELONG, MARK JEFFREY | Senior Vice President | 普通株式 | 購入 | 5,000 | $15.52 |
| 2022-08-11 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 購入 | 12,500 | $15.09 |
| 2022-08-11 | DELONG, MARK JEFFREY | Senior Vice President | 普通株式 | 売却 | 5,000 | $67.00 |
| 2022-08-11 | DELONG, MARK JEFFREY | Senior Vice President | ストックオプション | 売却 | 5,000 | $0.00 |
| 2022-08-11 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 30,000 | $65.63 |
| 2022-08-11 | TOWNSEND, ADAM J. | Chief Commercial Officer | ストックオプション | 売却 | 12,500 | $0.00 |
| 2022-08-11 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 売却 | 12,500 | $67.00 |
| 2022-08-08 | DELONG, MARK JEFFREY | Senior Vice President | 普通株式 | 購入 | 5,000 | $15.52 |
| 2022-08-08 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 売却 | 12,500 | $65.00 |
| 2022-08-08 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 購入 | 12,500 | $15.09 |
| 2022-08-08 | DELONG, MARK JEFFREY | Senior Vice President | ストックオプション | 売却 | 5,000 | $0.00 |
| 2022-08-08 | DELONG, MARK JEFFREY | Senior Vice President | 普通株式 | 売却 | 5,000 | $64.50 |
| 2022-08-08 | TOWNSEND, ADAM J. | Chief Commercial Officer | ストックオプション | 売却 | 12,500 | $0.00 |
| 2022-08-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 18,500 | $2.67 |
| 2022-08-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 12,000 | $62.50 |
| 2022-08-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 売却 | 18,500 | $0.00 |
| 2022-08-04 | DELONG, MARK JEFFREY | Senior Vice President | 普通株式 | 購入 | 10,000 | $15.52 |
| 2022-08-04 | DELONG, MARK JEFFREY | Senior Vice President | 普通株式 | 売却 | 5,000 | $59.50 |
| 2022-08-04 | DELONG, MARK JEFFREY | Senior Vice President | 普通株式 | 売却 | 5,000 | $62.00 |
| 2022-08-04 | DELONG, MARK JEFFREY | Senior Vice President | ストックオプション | 売却 | 10,000 | $0.00 |
| 2022-08-03 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 売却 | 5,000 | $56.43 |
| 2022-08-03 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 購入 | 5,000 | $15.09 |
| 2022-08-03 | TOWNSEND, ADAM J. | Chief Commercial Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2022-08-01 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 2,500 | $55.99 |
| 2022-07-27 | DELONG, MARK JEFFREY | Senior Vice President | 普通株式 | 購入 | 5,000 | $15.52 |
| 2022-07-27 | DELONG, MARK JEFFREY | Senior Vice President | ストックオプション | 売却 | 5,000 | $0.00 |
| 2022-07-27 | DELONG, MARK JEFFREY | Senior Vice President | 普通株式 | 売却 | 5,000 | $57.00 |
| 2022-07-21 | DUNLOP, A. SINCLAIR | Director | ストックオプション | 売却 | 9,606 | $0.00 |
| 2022-07-21 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 購入 | 9,606 | $14.00 |
| 2022-07-19 | DELONG, MARK JEFFREY | Senior Vice President | ストックオプション | 売却 | 5,000 | $0.00 |
| 2022-07-19 | DELONG, MARK JEFFREY | Senior Vice President | 普通株式 | 売却 | 5,000 | $56.42 |
| 2022-07-19 | DELONG, MARK JEFFREY | Senior Vice President | 普通株式 | 購入 | 5,000 | $15.52 |
| 2022-07-15 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 1,250 | $2.67 |
| 2022-07-15 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 1,250 | $0.00 |
| 2022-07-15 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 1,250 | $46.33 |
| 2022-07-11 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 購入 | 5,000 | $15.09 |
| 2022-07-11 | TOWNSEND, ADAM J. | Chief Commercial Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2022-07-11 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 売却 | 5,000 | $48.42 |
| 2022-07-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 売却 | 12,000 | $0.00 |
| 2022-07-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 売却 | 6,500 | $0.00 |
| 2022-07-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 12,000 | $2.67 |
| 2022-07-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 6,500 | $2.67 |
| 2022-07-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 12,000 | $47.95 |
| 2022-06-27 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 1,341 | $46.79 |
| 2022-06-23 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 15,000 | $45.00 |
| 2022-06-22 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 10,000 | $44.51 |
| 2022-06-17 | BROWN, VICTORIA L. | Program Team Lead | 普通株式 | 売却 | 2,698 | $45.00 |
| 2022-06-17 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 33,005 | $2.67 |
| 2022-06-17 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 売却 | 33,005 | $0.00 |
| 2022-06-16 | DELONG, MARK JEFFREY | Senior Vice President | 普通株式 | 購入 | 10,000 | $13.85 |
| 2022-06-16 | DELONG, MARK JEFFREY | Senior Vice President | 普通株式 | 売却 | 10,000 | $41.79 |
| 2022-06-16 | DELONG, MARK JEFFREY | Senior Vice President | ストックオプション | 売却 | 10,000 | $0.00 |
| 2022-06-15 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 1,250 | $39.29 |
| 2022-06-15 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 1,250 | $0.00 |
| 2022-06-15 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 1,250 | $2.67 |
| 2022-06-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 6,500 | $2.67 |
| 2022-06-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 売却 | 6,500 | $0.00 |
| 2022-06-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 売却 | 12,000 | $0.00 |
| 2022-06-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 12,000 | $2.67 |
| 2022-06-08 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 12,000 | $44.09 |
| 2022-06-01 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 2,500 | $41.78 |
| 2022-05-27 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | 普通株式 | 売却 | 10,000 | $43.00 |
| 2022-05-16 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 1,250 | $2.67 |
| 2022-05-16 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 1,250 | $39.18 |
| 2022-05-16 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 1,250 | $0.00 |
| 2022-05-02 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 2,500 | $43.56 |
| 2022-04-29 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 4,000 | $2.67 |
| 2022-04-29 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 売却 | 4,000 | $0.00 |
| 2022-04-29 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 4,000 | $44.43 |
| 2022-04-25 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | ストックオプション | 売却 | 22,500 | $0.00 |
| 2022-04-25 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 売却 | 3,750 | $0.00 |
| 2022-04-25 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 12,500 | $0.00 |
| 2022-04-25 | LEWIS, KAREN | Chief People Officer | 普通株式 | 売却 | 1,250 | $0.00 |
| 2022-04-25 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 売却 | 75,000 | $0.00 |
| 2022-04-25 | LEWIS, KAREN | Chief People Officer | ストックオプション | 売却 | 7,500 | $0.00 |
| 2022-04-25 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 5,000 | $50.00 |
| 2022-04-25 | EISELE, JEFFREY | Exec VP, Program Team Lead | 普通株式 | 売却 | 1,250 | $0.00 |
| 2022-04-25 | NICHOLSON, NUR | Chief Technical Officer | ストックオプション | 売却 | 11,250 | $0.00 |
| 2022-04-25 | NICHOLSON, NUR | Chief Technical Officer | 普通株式 | 売却 | 1,875 | $0.00 |
| 2022-04-22 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 購入 | 20,000 | $14.00 |
| 2022-04-22 | DUNLOP, A. SINCLAIR | Director | ストックオプション | 売却 | 20,000 | $0.00 |
| 2022-04-21 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 売却 | 11,250 | $0.00 |
| 2022-04-21 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | ストックオプション | 売却 | 11,250 | $0.00 |
| 2022-04-21 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 1,875 | $0.00 |
| 2022-04-21 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | ストックオプション | 売却 | 11,250 | $0.00 |
| 2022-04-21 | WATSON, DAVID O. | General Counsel | ストックオプション | 売却 | 11,250 | $0.00 |
| 2022-04-21 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 1,875 | $0.00 |
| 2022-04-21 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | 普通株式 | 売却 | 1,875 | $0.00 |
| 2022-04-21 | TOWNSEND, ADAM J. | Chief Commercial Officer | ストックオプション | 売却 | 11,250 | $0.00 |
| 2022-04-21 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 売却 | 1,875 | $0.00 |
| 2022-04-21 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 1,875 | $0.00 |
| 2022-04-20 | DELONG, MARK JEFFREY | Senior Vice President | 普通株式 | 購入 | 7,000 | $15.52 |
| 2022-04-20 | DELONG, MARK JEFFREY | Senior Vice President | ストックオプション | 売却 | 7,000 | $0.00 |
| 2022-04-20 | DELONG, MARK JEFFREY | Senior Vice President | 普通株式 | 売却 | 7,000 | $52.53 |
| 2022-04-14 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 1,250 | $50.90 |
| 2022-04-14 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 1,250 | $0.00 |
| 2022-04-14 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 1,250 | $2.67 |
| 2022-04-05 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | 普通株式 | 購入 | 609 | $13.85 |
| 2022-04-05 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | 普通株式 | 売却 | 609 | $60.09 |
| 2022-04-05 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | ストックオプション | 売却 | 609 | $0.00 |
| 2022-04-04 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | 普通株式 | 購入 | 3,504 | $13.85 |
| 2022-04-04 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | 普通株式 | 売却 | 818 | $55.84 |
| 2022-04-04 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | 普通株式 | 売却 | 1,437 | $56.86 |
| 2022-04-04 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | 普通株式 | 売却 | 1,249 | $57.81 |
| 2022-04-04 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | ストックオプション | 売却 | 3,504 | $0.00 |
| 2022-04-01 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | 普通株式 | 売却 | 11,496 | $55.05 |
| 2022-04-01 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | 普通株式 | 購入 | 11,496 | $13.85 |
| 2022-04-01 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | ストックオプション | 売却 | 11,496 | $0.00 |
| 2022-03-25 | BROWN, VICTORIA L. | Program Team Lead | 普通株式 | 売却 | 82 | $49.28 |
| 2022-03-15 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 375 | $39.57 |
| 2022-03-15 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 1,250 | $0.00 |
| 2022-03-15 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 1,250 | $2.67 |
| 2022-03-15 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 1,250 | $39.57 |
| 2022-03-15 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 購入 | 7,000 | $4.31 |
| 2022-03-15 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | ストックオプション | 売却 | 7,000 | $0.00 |
| 2022-03-01 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 375 | $43.53 |
| 2022-02-23 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 購入 | 4,100 | $4.31 |
| 2022-02-23 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | ストックオプション | 売却 | 4,100 | $0.00 |
| 2022-02-15 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 375 | $45.43 |
| 2022-02-15 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 1,250 | $0.00 |
| 2022-02-15 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 1,250 | $45.43 |
| 2022-02-15 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 1,250 | $2.67 |
| 2022-02-14 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | ストックオプション | 売却 | 720 | $0.00 |
| 2022-02-14 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | ストックオプション | 売却 | 3,600 | $0.00 |
| 2022-02-14 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 購入 | 3,600 | $4.31 |
| 2022-02-14 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | 普通株式 | 購入 | 720 | $26.73 |
| 2022-02-11 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | 普通株式 | 売却 | 1,666 | $46.80 |
| 2022-02-10 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 491 | $47.12 |
| 2022-02-10 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | 普通株式 | 売却 | 10,000 | $50.00 |
| 2022-02-10 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | 普通株式 | 購入 | 10,000 | $13.85 |
| 2022-02-10 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | 普通株式 | 売却 | 678 | $47.12 |
| 2022-02-10 | BROWN, VICTORIA L. | Program Team Lead | 普通株式 | 売却 | 175 | $47.12 |
| 2022-02-10 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 売却 | 875 | $47.12 |
| 2022-02-10 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 2,523 | $47.12 |
| 2022-02-10 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 1,057 | $47.12 |
| 2022-02-10 | DELONG, MARK JEFFREY | Senior Vice President | ストックオプション | 購入 | 6,952 | $0.00 |
| 2022-02-10 | DELONG, MARK JEFFREY | Senior Vice President | 普通株式 | 購入 | 4,901 | $0.00 |
| 2022-02-10 | DELONG, MARK JEFFREY | Senior Vice President | 普通株式 | 売却 | 271 | $47.12 |
| 2022-02-10 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 705 | $47.12 |
| 2022-02-10 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | ストックオプション | 売却 | 10,000 | $0.00 |
| 2022-02-10 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 売却 | 895 | $47.12 |
| 2022-02-08 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | 普通株式 | 購入 | 10,000 | $13.85 |
| 2022-02-08 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | 普通株式 | 売却 | 10,000 | $45.00 |
| 2022-02-08 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | ストックオプション | 売却 | 10,000 | $0.00 |
| 2022-02-01 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 375 | $40.58 |
| 2022-01-31 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | 普通株式 | 売却 | 1,233 | $38.47 |
| 2022-01-28 | BROWN, VICTORIA L. | Program Team Lead | 普通株式 | 売却 | 434 | $38.59 |
| 2022-01-28 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | 普通株式 | 売却 | 642 | $38.59 |
| 2022-01-28 | LEWIS, KAREN | Chief People Officer | 普通株式 | 売却 | 434 | $38.59 |
| 2022-01-28 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 2,024 | $38.59 |
| 2022-01-28 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 931 | $38.59 |
| 2022-01-28 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 売却 | 800 | $38.59 |
| 2022-01-28 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 売却 | 650 | $38.59 |
| 2022-01-28 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 650 | $38.59 |
| 2022-01-28 | NICHOLSON, NUR | Chief Technical Officer | 普通株式 | 売却 | 650 | $38.59 |
| 2022-01-28 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 650 | $38.59 |
| 2022-01-28 | EISELE, JEFFREY | Exec VP, Program Team Lead | 普通株式 | 売却 | 434 | $38.59 |
| 2022-01-28 | DELONG, MARK JEFFREY | Senior Vice President | 普通株式 | 売却 | 434 | $38.59 |
| 2022-01-21 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 購入 | 30,787 | $0.00 |
| 2022-01-21 | WATSON, DAVID O. | General Counsel | ストックオプション | 購入 | 36,951 | $0.00 |
| 2022-01-21 | LEWIS, KAREN | Chief People Officer | 普通株式 | 購入 | 17,466 | $0.00 |
| 2022-01-21 | LEWIS, KAREN | Chief People Officer | ストックオプション | 購入 | 24,774 | $0.00 |
| 2022-01-21 | BROWN, VICTORIA L. | Program Team Lead | 普通株式 | 購入 | 17,466 | $0.00 |
| 2022-01-21 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | ストックオプション | 売却 | 3,021 | $0.00 |
| 2022-01-21 | CHOPAS, JAMES GEORGE | VP/Chief Accounting Officer | ストックオプション | 購入 | 15,116 | $0.00 |
| 2022-01-21 | DELONG, MARK JEFFREY | Senior Vice President | 普通株式 | 購入 | 13,913 | $0.00 |
| 2022-01-21 | DELONG, MARK JEFFREY | Senior Vice President | ストックオプション | 購入 | 19,735 | $0.00 |
| 2022-01-21 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 26,051 | $0.00 |
| 2022-01-21 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 購入 | 36,951 | $0.00 |
| 2022-01-21 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 購入 | 26,051 | $0.00 |
| 2022-01-21 | TOWNSEND, ADAM J. | Chief Commercial Officer | ストックオプション | 購入 | 36,951 | $0.00 |
| 2022-01-21 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 購入 | 26,051 | $0.00 |
| 2022-01-21 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | ストックオプション | 購入 | 36,951 | $0.00 |
| 2022-01-21 | NICHOLSON, NUR | Chief Technical Officer | 普通株式 | 購入 | 26,051 | $0.00 |
| 2022-01-21 | NICHOLSON, NUR | Chief Technical Officer | ストックオプション | 購入 | 36,951 | $0.00 |
| 2022-01-21 | EISELE, JEFFREY | Exec VP, Program Team Lead | 普通株式 | 購入 | 26,051 | $0.00 |
| 2022-01-21 | EISELE, JEFFREY | Exec VP, Program Team Lead | ストックオプション | 購入 | 36,951 | $0.00 |
| 2022-01-21 | WATSON, DAVID O. | General Counsel | 普通株式 | 購入 | 26,051 | $0.00 |
| 2022-01-21 | CHOPAS, JAMES GEORGE | VP/Chief Accounting Officer | ストックオプション | 購入 | 9,892 | $0.00 |
| 2022-01-21 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | 普通株式 | 購入 | 3,021 | $26.73 |
| 2022-01-21 | CHOPAS, JAMES GEORGE | VP/Chief Accounting Officer | 普通株式 | 購入 | 6,974 | $0.00 |
| 2022-01-21 | DELONG, MARK JEFFREY | Senior Vice President | ストックオプション | 購入 | 15,024 | $0.00 |
| 2022-01-21 | DELONG, MARK JEFFREY | Senior Vice President | 普通株式 | 購入 | 10,592 | $0.00 |
| 2022-01-21 | BROWN, VICTORIA L. | Program Team Lead | ストックオプション | 購入 | 24,774 | $0.00 |
| 2022-01-21 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | ストックオプション | 購入 | 43,670 | $0.00 |
| 2022-01-21 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 購入 | 150,672 | $0.00 |
| 2022-01-21 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 106,244 | $0.00 |
| 2022-01-21 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | ストックオプション | 購入 | 36,951 | $0.00 |
| 2022-01-21 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | 普通株式 | 購入 | 26,051 | $0.00 |
| 2022-01-21 | CHOPAS, JAMES GEORGE | VP/Chief Accounting Officer | 普通株式 | 購入 | 10,657 | $0.00 |
| 2022-01-14 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | ストックオプション | 売却 | 3,400 | $0.00 |
| 2022-01-14 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 375 | $40.56 |
| 2022-01-14 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 購入 | 3,400 | $4.31 |
| 2022-01-14 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 1,250 | $40.56 |
| 2022-01-14 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 1,250 | $0.00 |
| 2022-01-14 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 1,250 | $2.67 |
| 2022-01-12 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 購入 | 3,661 | $3.76 |
| 2022-01-12 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | ストックオプション | 売却 | 1,500 | $0.00 |
| 2022-01-12 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | ストックオプション | 売却 | 3,661 | $0.00 |
| 2022-01-12 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 購入 | 1,500 | $4.31 |
| 2022-01-03 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 375 | $47.31 |
| 2022-01-01 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 購入 | 4,230 | $0.00 |
| 2022-01-01 | O'BRIEN, STEPHANIE MONAGHAN | Director | ストックオプション | 購入 | 8,554 | $0.00 |
| 2022-01-01 | DUNLOP, A. SINCLAIR | Director | ストックオプション | 購入 | 8,554 | $0.00 |
| 2022-01-01 | CHAN, GERALD | Director | 普通株式 | 購入 | 4,230 | $0.00 |
| 2022-01-01 | CHAN, GERALD | Director | ストックオプション | 購入 | 8,554 | $0.00 |
| 2022-01-01 | FONTEYNE, PAUL R. | Director | 普通株式 | 購入 | 4,230 | $0.00 |
| 2022-01-01 | FONTEYNE, PAUL R. | Director | ストックオプション | 購入 | 8,554 | $0.00 |
| 2022-01-01 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 4,230 | $0.00 |
| 2022-01-01 | MACHIELS, ALEC | Director | ストックオプション | 購入 | 8,554 | $0.00 |
| 2022-01-01 | O'BRIEN, STEPHANIE MONAGHAN | Director | 普通株式 | 購入 | 4,230 | $0.00 |
| 2021-12-27 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 1,200 | $48.50 |
| 2021-12-22 | EISELE, JEFFREY | Exec VP, Program Team Lead | 普通株式 | 売却 | 89 | $47.82 |
| 2021-12-22 | WATSON, DAVID O. | General Counsel | ストックオプション | 売却 | 4,826 | $0.00 |
| 2021-12-22 | WATSON, DAVID O. | General Counsel | ストックオプション | 売却 | 5,174 | $0.00 |
| 2021-12-22 | WATSON, DAVID O. | General Counsel | ストックオプション | 売却 | 5,397 | $0.00 |
| 2021-12-22 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 5,097 | $47.86 |
| 2021-12-22 | WATSON, DAVID O. | General Counsel | 普通株式 | 購入 | 5,397 | $14.95 |
| 2021-12-22 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 300 | $48.58 |
| 2021-12-22 | WATSON, DAVID O. | General Counsel | ストックオプション | 売却 | 4,715 | $0.00 |
| 2021-12-22 | WATSON, DAVID O. | General Counsel | 普通株式 | 購入 | 5,174 | $13.85 |
| 2021-12-22 | WATSON, DAVID O. | General Counsel | 普通株式 | 購入 | 4,826 | $13.85 |
| 2021-12-22 | WATSON, DAVID O. | General Counsel | 普通株式 | 購入 | 4,715 | $14.95 |
| 2021-12-22 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 5,174 | $47.72 |
| 2021-12-15 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 3,000 | $0.00 |
| 2021-12-15 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 375 | $42.88 |
| 2021-12-15 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 3,000 | $2.67 |
| 2021-12-15 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 3,000 | $42.88 |
| 2021-12-08 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 購入 | 7,000 | $3.76 |
| 2021-12-08 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | ストックオプション | 売却 | 7,000 | $0.00 |
| 2021-12-01 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 375 | $42.40 |
| 2021-11-18 | MORNINGSIDE, VENTURE INVESTMENTS LTD | 10% Owner | 普通株式 | 購入 | 250,000 | $40.00 |
| 2021-11-15 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 3,000 | $0.00 |
| 2021-11-15 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 3,000 | $2.67 |
| 2021-11-15 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 3,000 | $43.50 |
| 2021-11-15 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 625 | $43.50 |
| 2021-11-04 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 3,000 | $0.00 |
| 2021-11-04 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 3,000 | $35.00 |
| 2021-11-04 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 3,000 | $2.67 |
| 2021-11-01 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 625 | $30.70 |
| 2021-10-26 | BROWN, VICTORIA L. | Program Team Lead | 普通株式 | 購入 | 882 | $0.00 |
| 2021-10-20 | DELONG, MARK JEFFREY | Senior Vice President | 普通株式 | 購入 | 882 | $0.00 |
| 2021-10-20 | CHOPAS, JAMES GEORGE | VP/Chief Accounting Officer | 普通株式 | 購入 | 882 | $0.00 |
| 2021-10-14 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 750 | $34.57 |
| 2021-10-01 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 750 | $33.26 |
| 2021-09-28 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 購入 | 4,000 | $3.76 |
| 2021-09-28 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | ストックオプション | 売却 | 4,000 | $0.00 |
| 2021-09-10 | DUNLOP, A. SINCLAIR | Director | ストックオプション | 売却 | 6,894 | $0.00 |
| 2021-09-10 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 購入 | 6,894 | $14.00 |
| 2021-09-10 | WATSON, DAVID O. | General Counsel | ストックオプション | 売却 | 954 | $0.00 |
| 2021-09-10 | WATSON, DAVID O. | General Counsel | 普通株式 | 購入 | 954 | $4.31 |
| 2021-08-30 | CHOPAS, JAMES GEORGE | See Remarks | 普通株式 | 購入 | 7,600 | $0.00 |
| 2021-08-30 | CHOPAS, JAMES GEORGE | See Remarks | ストックオプション | 購入 | 21,750 | $0.00 |
| 2021-08-16 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 2,500 | $2.67 |
| 2021-08-16 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 2,500 | $56.95 |
| 2021-08-16 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 2,500 | $0.00 |
| 2021-08-02 | PERRY, NICOLE D | Vice President - Accounting | ストックオプション | 売却 | 1,000 | $0.00 |
| 2021-08-02 | PERRY, NICOLE D | Vice President - Accounting | 普通株式 | 売却 | 1,000 | $63.99 |
| 2021-08-02 | PERRY, NICOLE D | Vice President - Accounting | 普通株式 | 購入 | 1,000 | $3.76 |
| 2021-08-02 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 250 | $63.99 |
| 2021-07-21 | DELONG, MARK JEFFREY | Senior Vice President | 普通株式 | 売却 | 1,000 | $65.00 |
| 2021-07-21 | DELONG, MARK JEFFREY | Senior Vice President | ストックオプション | 売却 | 1,000 | $0.00 |
| 2021-07-21 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 14,410 | $4.31 |
| 2021-07-21 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 売却 | 14,410 | $0.00 |
| 2021-07-21 | DELONG, MARK JEFFREY | Senior Vice President | 普通株式 | 購入 | 1,000 | $15.52 |
| 2021-07-15 | DELONG, MARK JEFFREY | Senior Vice President | 普通株式 | 売却 | 1,000 | $62.30 |
| 2021-07-15 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 2,500 | $0.00 |
| 2021-07-15 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 2,500 | $62.30 |
| 2021-07-15 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 2,500 | $2.67 |
| 2021-07-15 | DELONG, MARK JEFFREY | Senior Vice President | ストックオプション | 売却 | 1,000 | $0.00 |
| 2021-07-15 | DELONG, MARK JEFFREY | Senior Vice President | 普通株式 | 購入 | 1,000 | $15.52 |
| 2021-07-14 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 500 | $64.68 |
| 2021-07-08 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 250 | $65.68 |
| 2021-07-01 | PERRY, NICOLE D | Vice President - Accounting | 普通株式 | 購入 | 1,000 | $3.76 |
| 2021-07-01 | PERRY, NICOLE D | Vice President - Accounting | 普通株式 | 売却 | 1,000 | $64.00 |
| 2021-07-01 | PERRY, NICOLE D | Vice President - Accounting | ストックオプション | 売却 | 1,000 | $0.00 |
| 2021-06-28 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 購入 | 9,000 | $3.76 |
| 2021-06-28 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | ストックオプション | 売却 | 9,000 | $0.00 |
| 2021-06-24 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 6,250 | $2.67 |
| 2021-06-24 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 6,250 | $65.61 |
| 2021-06-24 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 売却 | 6,250 | $0.00 |
| 2021-06-21 | WATSON, DAVID O. | General Counsel | ストックオプション | 売却 | 489 | $0.00 |
| 2021-06-21 | WATSON, DAVID O. | General Counsel | 普通株式 | 購入 | 489 | $4.31 |
| 2021-06-15 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 2,500 | $2.67 |
| 2021-06-15 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 2,500 | $64.83 |
| 2021-06-15 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 2,500 | $0.00 |
| 2021-06-15 | DELONG, MARK JEFFREY | Senior Vice President | 普通株式 | 購入 | 4,000 | $15.52 |
| 2021-06-15 | DELONG, MARK JEFFREY | Senior Vice President | 普通株式 | 売却 | 4,000 | $64.96 |
| 2021-06-15 | DELONG, MARK JEFFREY | Senior Vice President | ストックオプション | 売却 | 4,000 | $0.00 |
| 2021-06-14 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 500 | $61.84 |
| 2021-06-11 | PERRY, NICOLE D | Vice President - Accounting | 普通株式 | 購入 | 1,000 | $3.20 |
| 2021-06-11 | PERRY, NICOLE D | Vice President - Accounting | 普通株式 | 売却 | 1,000 | $61.56 |
| 2021-06-11 | PERRY, NICOLE D | Vice President - Accounting | ストックオプション | 売却 | 1,000 | $0.00 |
| 2021-06-10 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | 普通株式 | 売却 | 3,417 | $60.00 |
| 2021-06-08 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | ストックオプション | 売却 | 39,880 | $0.00 |
| 2021-06-08 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 購入 | 39,880 | $10.03 |
| 2021-06-01 | PERRY, NICOLE D | Vice President - Accounting | ストックオプション | 売却 | 1,000 | $0.00 |
| 2021-06-01 | PERRY, NICOLE D | Vice President - Accounting | 普通株式 | 購入 | 1,000 | $3.76 |
| 2021-06-01 | PERRY, NICOLE D | Vice President - Accounting | 普通株式 | 売却 | 1,000 | $56.40 |
| 2021-06-01 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 31,855 | $0.00 |
| 2021-06-01 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 購入 | 13,108 | $0.00 |
| 2021-06-01 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 購入 | 2,682 | $0.00 |
| 2021-05-28 | WATSON, DAVID O. | General Counsel | ストックオプション | 売却 | 489 | $0.00 |
| 2021-05-28 | WATSON, DAVID O. | General Counsel | 普通株式 | 購入 | 489 | $4.31 |
| 2021-05-24 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 売却 | 6,250 | $0.00 |
| 2021-05-24 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 6,250 | $47.40 |
| 2021-05-24 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 6,250 | $2.67 |
| 2021-05-20 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 5,773 | $48.10 |
| 2021-05-19 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 7,612 | $50.00 |
| 2021-05-18 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 36,387 | $53.78 |
| 2021-05-18 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 22,318 | $54.57 |
| 2021-05-18 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 1,200 | $52.01 |
| 2021-05-18 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 10,388 | $53.50 |
| 2021-05-18 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 800 | $54.02 |
| 2021-05-18 | DELONG, MARK JEFFREY | Senior Vice President | 普通株式 | 購入 | 2,000 | $15.52 |
| 2021-05-18 | DELONG, MARK JEFFREY | Senior Vice President | 普通株式 | 売却 | 2,000 | $55.00 |
| 2021-05-18 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 64,179 | $51.66 |
| 2021-05-18 | DELONG, MARK JEFFREY | Senior Vice President | ストックオプション | 売却 | 2,000 | $0.00 |
| 2021-05-18 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 14,216 | $52.63 |
| 2021-05-14 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 500 | $45.39 |
| 2021-05-14 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 2,500 | $2.67 |
| 2021-05-14 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 2,500 | $45.39 |
| 2021-05-14 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 2,500 | $0.00 |
| 2021-05-03 | PERRY, NICOLE D | Vice President - Accounting | ストックオプション | 売却 | 1,000 | $0.00 |
| 2021-05-03 | PERRY, NICOLE D | Vice President - Accounting | 普通株式 | 売却 | 1,000 | $50.73 |
| 2021-05-03 | PERRY, NICOLE D | Vice President - Accounting | 普通株式 | 購入 | 1,000 | $3.76 |
| 2021-05-03 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 600 | $50.73 |
| 2021-04-30 | PERRY, NICOLE D | Vice President - Accounting | 普通株式 | 売却 | 1,000 | $50.00 |
| 2021-04-30 | PERRY, NICOLE D | Vice President - Accounting | ストックオプション | 売却 | 1,000 | $0.00 |
| 2021-04-30 | PERRY, NICOLE D | Vice President - Accounting | 普通株式 | 購入 | 1,000 | $3.76 |
| 2021-04-28 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 4,500 | $2.67 |
| 2021-04-28 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 売却 | 4,500 | $0.00 |
| 2021-04-23 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 購入 | 10,000 | $14.00 |
| 2021-04-23 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 6,250 | $46.13 |
| 2021-04-23 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 売却 | 6,250 | $0.00 |
| 2021-04-23 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 6,250 | $2.67 |
| 2021-04-23 | DUNLOP, A. SINCLAIR | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2021-04-22 | WATSON, DAVID O. | General Counsel | ストックオプション | 売却 | 489 | $0.00 |
| 2021-04-22 | WATSON, DAVID O. | General Counsel | 普通株式 | 購入 | 489 | $4.31 |
| 2021-04-21 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 2,500 | $0.00 |
| 2021-04-21 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 2,500 | $2.67 |
| 2021-04-21 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 2,500 | $45.76 |
| 2021-04-16 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 購入 | 50,000 | $14.00 |
| 2021-04-16 | DUNLOP, A. SINCLAIR | Director | ストックオプション | 売却 | 50,000 | $0.00 |
| 2021-04-14 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 500 | $42.82 |
| 2021-04-01 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 600 | $43.41 |
| 2021-03-25 | BROWN, VICTORIA L. | Program Team Lead | 普通株式 | 売却 | 82 | $41.16 |
| 2021-03-22 | WATSON, DAVID O. | General Counsel | ストックオプション | 売却 | 978 | $0.00 |
| 2021-03-22 | WATSON, DAVID O. | General Counsel | 普通株式 | 購入 | 978 | $4.31 |
| 2021-03-15 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 500 | $46.77 |
| 2021-03-15 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 2,500 | $2.67 |
| 2021-03-15 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 2,500 | $46.77 |
| 2021-03-15 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 2,500 | $0.00 |
| 2021-03-10 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 売却 | 6,250 | $0.00 |
| 2021-03-10 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 6,250 | $50.74 |
| 2021-03-10 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 6,250 | $2.67 |
| 2021-03-05 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | ストックオプション | 売却 | 5,000 | $0.00 |
| 2021-03-05 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 5,000 | $48.62 |
| 2021-03-05 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 購入 | 5,000 | $3.20 |
| 2021-03-01 | BROWN, VICTORIA L. | Program Team Lead | ストックオプション | 購入 | 7,500 | $0.00 |
| 2021-03-01 | PERRY, NICOLE D | Vice President - Accounting | 普通株式 | 売却 | 2,000 | $50.00 |
| 2021-03-01 | BROWN, VICTORIA L. | Program Team Lead | 普通株式 | 購入 | 1,250 | $0.00 |
| 2021-03-01 | EISELE, JEFFREY | Exec VP, Program Team Lead | ストックオプション | 購入 | 7,500 | $0.00 |
| 2021-03-01 | PERRY, NICOLE D | Vice President - Accounting | 普通株式 | 購入 | 2,000 | $3.76 |
| 2021-03-01 | EISELE, JEFFREY | Exec VP, Program Team Lead | 普通株式 | 購入 | 1,250 | $0.00 |
| 2021-03-01 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 600 | $48.58 |
| 2021-03-01 | PERRY, NICOLE D | Vice President - Accounting | ストックオプション | 売却 | 2,000 | $0.00 |
| 2021-02-16 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 2,500 | $0.00 |
| 2021-02-16 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 500 | $46.00 |
| 2021-02-16 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 2,500 | $2.67 |
| 2021-02-16 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 2,500 | $46.00 |
| 2021-02-10 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 売却 | 688 | $47.72 |
| 2021-02-10 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 2,523 | $47.72 |
| 2021-02-10 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 688 | $47.72 |
| 2021-02-10 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 売却 | 688 | $47.72 |
| 2021-02-10 | PERRY, NICOLE D | Vice President - Accounting | 普通株式 | 売却 | 153 | $47.72 |
| 2021-02-10 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 売却 | 858 | $47.72 |
| 2021-02-10 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 468 | $47.72 |
| 2021-02-10 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | 普通株式 | 売却 | 680 | $47.72 |
| 2021-02-10 | BROWN, VICTORIA L. | Program Team Lead | 普通株式 | 売却 | 144 | $47.72 |
| 2021-02-09 | PERRY, NICOLE D | Vice President - Accounting | ストックオプション | 売却 | 2,000 | $0.00 |
| 2021-02-09 | PERRY, NICOLE D | Vice President - Accounting | 普通株式 | 購入 | 2,000 | $3.76 |
| 2021-02-09 | PERRY, NICOLE D | Vice President - Accounting | 普通株式 | 売却 | 2,000 | $50.00 |
| 2021-02-01 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 600 | $44.00 |
| 2021-01-28 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | ストックオプション | 購入 | 11,250 | $0.00 |
| 2021-01-28 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 購入 | 75,000 | $0.00 |
| 2021-01-28 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 購入 | 7,500 | $0.00 |
| 2021-01-28 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | 普通株式 | 購入 | 1,875 | $0.00 |
| 2021-01-28 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | ストックオプション | 購入 | 45,000 | $0.00 |
| 2021-01-28 | BROWN, VICTORIA L. | Program Team Lead | 普通株式 | 購入 | 5,000 | $0.00 |
| 2021-01-28 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 購入 | 7,500 | $0.00 |
| 2021-01-28 | TOWNSEND, ADAM J. | Chief Commercial Officer | 普通株式 | 購入 | 1,875 | $0.00 |
| 2021-01-28 | TOWNSEND, ADAM J. | Chief Commercial Officer | ストックオプション | 購入 | 45,000 | $0.00 |
| 2021-01-28 | TOWNSEND, ADAM J. | Chief Commercial Officer | ストックオプション | 購入 | 11,250 | $0.00 |
| 2021-01-28 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 購入 | 7,500 | $0.00 |
| 2021-01-28 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 購入 | 1,875 | $0.00 |
| 2021-01-28 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | ストックオプション | 購入 | 45,000 | $0.00 |
| 2021-01-28 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | ストックオプション | 購入 | 11,250 | $0.00 |
| 2021-01-28 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 25,000 | $0.00 |
| 2021-01-28 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 12,500 | $0.00 |
| 2021-01-28 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 購入 | 150,000 | $0.00 |
| 2021-01-28 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 購入 | 3,750 | $0.00 |
| 2021-01-28 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | ストックオプション | 購入 | 45,000 | $0.00 |
| 2021-01-28 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | ストックオプション | 購入 | 22,500 | $0.00 |
| 2021-01-28 | WATSON, DAVID O. | General Counsel | 普通株式 | 購入 | 7,500 | $0.00 |
| 2021-01-28 | WATSON, DAVID O. | General Counsel | 普通株式 | 購入 | 1,875 | $0.00 |
| 2021-01-28 | WATSON, DAVID O. | General Counsel | ストックオプション | 購入 | 45,000 | $0.00 |
| 2021-01-28 | WATSON, DAVID O. | General Counsel | ストックオプション | 購入 | 11,250 | $0.00 |
| 2021-01-28 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | 普通株式 | 購入 | 7,500 | $0.00 |
| 2021-01-28 | NICHOLSON, NUR | Chief Technical Officer | 普通株式 | 購入 | 7,500 | $0.00 |
| 2021-01-28 | NICHOLSON, NUR | Chief Technical Officer | 普通株式 | 購入 | 1,875 | $0.00 |
| 2021-01-28 | NICHOLSON, NUR | Chief Technical Officer | ストックオプション | 購入 | 11,250 | $0.00 |
| 2021-01-28 | LEWIS, KAREN | Chief People Officer | 普通株式 | 購入 | 5,000 | $0.00 |
| 2021-01-28 | LEWIS, KAREN | Chief People Officer | 普通株式 | 購入 | 1,250 | $0.00 |
| 2021-01-28 | LEWIS, KAREN | Chief People Officer | ストックオプション | 購入 | 30,000 | $0.00 |
| 2021-01-28 | BROWN, VICTORIA L. | Program Team Lead | ストックオプション | 購入 | 30,000 | $0.00 |
| 2021-01-28 | PERRY, NICOLE D | Vice President - Accounting | 普通株式 | 購入 | 2,500 | $0.00 |
| 2021-01-28 | PERRY, NICOLE D | Vice President - Accounting | ストックオプション | 購入 | 15,000 | $0.00 |
| 2021-01-28 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 7,500 | $0.00 |
| 2021-01-28 | DESCHATELETS, PASCAL | Chief Scientific Officer | 普通株式 | 購入 | 1,875 | $0.00 |
| 2021-01-28 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 購入 | 45,000 | $0.00 |
| 2021-01-28 | DESCHATELETS, PASCAL | Chief Scientific Officer | ストックオプション | 購入 | 11,250 | $0.00 |
| 2021-01-28 | NICHOLSON, NUR | Chief Technical Officer | ストックオプション | 購入 | 45,000 | $0.00 |
| 2021-01-28 | LEWIS, KAREN | Chief People Officer | ストックオプション | 購入 | 7,500 | $0.00 |
| 2021-01-28 | EISELE, JEFFREY | Exec VP, Program Team Lead | 普通株式 | 購入 | 5,000 | $0.00 |
| 2021-01-28 | EISELE, JEFFREY | Exec VP, Program Team Lead | ストックオプション | 購入 | 30,000 | $0.00 |
| 2021-01-27 | WATSON, DAVID O. | General Counsel | 普通株式 | 購入 | 23,441 | $3.76 |
| 2021-01-27 | WATSON, DAVID O. | General Counsel | ストックオプション | 売却 | 20,042 | $0.00 |
| 2021-01-27 | WATSON, DAVID O. | General Counsel | ストックオプション | 売却 | 23,441 | $0.00 |
| 2021-01-27 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 39,785 | $3.76 |
| 2021-01-27 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 31,992 | $4.31 |
| 2021-01-27 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 売却 | 39,785 | $0.00 |
| 2021-01-27 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 売却 | 31,992 | $0.00 |
| 2021-01-27 | WATSON, DAVID O. | General Counsel | 普通株式 | 購入 | 20,042 | $4.31 |
| 2021-01-25 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 購入 | 3,500 | $3.20 |
| 2021-01-25 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | ストックオプション | 売却 | 11,500 | $0.00 |
| 2021-01-25 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | ストックオプション | 売却 | 3,500 | $0.00 |
| 2021-01-25 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 購入 | 11,500 | $3.76 |
| 2021-01-15 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 2,500 | $2.67 |
| 2021-01-15 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 2,500 | $53.15 |
| 2021-01-15 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 2,500 | $0.00 |
| 2021-01-14 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 4,000 | $51.99 |
| 2021-01-04 | PERRY, NICOLE D | Vice President - Accounting | 普通株式 | 購入 | 2,000 | $3.76 |
| 2021-01-04 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 600 | $57.24 |
| 2021-01-04 | PERRY, NICOLE D | Vice President - Accounting | 普通株式 | 売却 | 2,000 | $57.24 |
| 2021-01-04 | PERRY, NICOLE D | Vice President - Accounting | ストックオプション | 売却 | 2,000 | $0.00 |
| 2021-01-01 | MACHIELS, ALEC | Director | ストックオプション | 購入 | 27,600 | $0.00 |
| 2021-01-01 | FONTEYNE, PAUL R. | Director | ストックオプション | 購入 | 27,600 | $0.00 |
| 2021-01-01 | CHAN, GERALD | Director | ストックオプション | 購入 | 27,600 | $0.00 |
| 2021-01-01 | O'BRIEN, STEPHANIE MONAGHAN | Director | ストックオプション | 購入 | 27,600 | $0.00 |
| 2021-01-01 | DUNLOP, A. SINCLAIR | Director | ストックオプション | 購入 | 27,600 | $0.00 |
| 2020-12-23 | EISELE, JEFFREY | Exec VP, Program Team Lead | 普通株式 | 購入 | 1,211 | $0.00 |
| 2020-12-15 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 2,500 | $0.00 |
| 2020-12-15 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 2,500 | $52.16 |
| 2020-12-15 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $52.16 |
| 2020-12-15 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 2,500 | $2.67 |
| 2020-12-14 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 7,654 | $53.86 |
| 2020-12-14 | WATSON, DAVID O. | General Counsel | 普通株式 | 購入 | 8,398 | $13.85 |
| 2020-12-14 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 214 | $56.25 |
| 2020-12-14 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 17,132 | $55.01 |
| 2020-12-14 | WATSON, DAVID O. | General Counsel | ストックオプション | 売却 | 8,398 | $0.00 |
| 2020-12-14 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 200 | $55.91 |
| 2020-12-14 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 900 | $55.00 |
| 2020-12-14 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 900 | $53.86 |
| 2020-12-14 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 1,163 | $52.73 |
| 2020-12-14 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 2,526 | $51.32 |
| 2020-12-14 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 2,709 | $50.61 |
| 2020-12-11 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 9,935 | $50.00 |
| 2020-12-11 | WATSON, DAVID O. | General Counsel | 普通株式 | 購入 | 9,935 | $13.85 |
| 2020-12-11 | WATSON, DAVID O. | General Counsel | ストックオプション | 売却 | 9,935 | $0.00 |
| 2020-12-08 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | 普通株式 | 購入 | 7,482 | $26.73 |
| 2020-12-08 | SCHEIBLER, LUKAS | CHIEF INNOVATION OFFICER | ストックオプション | 売却 | 7,482 | $0.00 |
| 2020-12-07 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 9,094 | $50.41 |
| 2020-12-07 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 9,470 | $51.00 |
| 2020-12-04 | PERRY, NICOLE D | Vice President - Accounting | 普通株式 | 購入 | 18,000 | $3.76 |
| 2020-12-04 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 5,052 | $50.04 |
| 2020-12-04 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | ストックオプション | 売却 | 7,250 | $0.00 |
| 2020-12-04 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 購入 | 7,250 | $3.20 |
| 2020-12-04 | PERRY, NICOLE D | Vice President - Accounting | ストックオプション | 売却 | 18,000 | $0.00 |
| 2020-12-04 | PERRY, NICOLE D | Vice President - Accounting | 普通株式 | 売却 | 18,000 | $50.00 |
| 2020-12-04 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 1,384 | $51.05 |
| 2020-12-01 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 600 | $48.25 |
| 2020-12-01 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 40,000 | $3.76 |
| 2020-12-01 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 売却 | 40,000 | $0.00 |
| 2020-11-16 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 2,500 | $2.67 |
| 2020-11-16 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 2,500 | $0.00 |
| 2020-11-16 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 2,500 | $39.38 |
| 2020-11-16 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $39.38 |
| 2020-11-16 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | ストックオプション | 売却 | 5,750 | $0.00 |
| 2020-11-16 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 購入 | 5,750 | $3.20 |
| 2020-11-02 | GROSSI, FEDERICO | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 600 | $31.09 |
| 2020-10-15 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 2,500 | $2.67 |
| 2020-10-15 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 2,500 | $35.00 |
| 2020-10-15 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 2,500 | $0.00 |
| 2020-10-15 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $34.46 |
| 2020-10-07 | BROWN, VICTORIA L. | Program Team Lead | 普通株式 | 売却 | 12,000 | $35.00 |
| 2020-10-07 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 7,500 | $2.67 |
| 2020-10-07 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 7,500 | $35.00 |
| 2020-10-07 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 7,500 | $0.00 |
| 2020-10-07 | BROWN, VICTORIA L. | Program Team Lead | 普通株式 | 購入 | 12,000 | $18.98 |
| 2020-10-07 | BROWN, VICTORIA L. | Program Team Lead | ストックオプション | 売却 | 12,000 | $0.00 |
| 2020-10-01 | GROSSI, FEDERICO | See Remarks | 普通株式 | 売却 | 600 | $30.22 |
| 2020-09-15 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $30.96 |
| 2020-09-01 | GROSSI, FEDERICO | See Remarks | 普通株式 | 売却 | 600 | $31.58 |
| 2020-08-20 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 3,457 | $30.00 |
| 2020-08-18 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 1,543 | $30.00 |
| 2020-08-03 | GROSSI, FEDERICO | See Remarks | 普通株式 | 売却 | 600 | $26.28 |
| 2020-07-15 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $32.12 |
| 2020-07-01 | GROSSI, FEDERICO | See Remarks | 普通株式 | 売却 | 850 | $32.43 |
| 2020-06-15 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 2,500 | $30.21 |
| 2020-06-15 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 2,500 | $0.00 |
| 2020-06-15 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $30.21 |
| 2020-06-15 | GROSSI, FEDERICO | See Remarks | 普通株式 | 売却 | 856 | $30.21 |
| 2020-06-15 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 2,500 | $2.67 |
| 2020-05-15 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 2,500 | $2.67 |
| 2020-05-15 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 2,500 | $30.00 |
| 2020-05-15 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 2,500 | $0.00 |
| 2020-05-15 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $29.92 |
| 2020-05-08 | FONTEYNE, PAUL R. | Director | 普通株式 | 購入 | 5,000 | $31.81 |
| 2020-04-15 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 2,500 | $0.00 |
| 2020-04-15 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $29.77 |
| 2020-04-15 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 2,500 | $2.67 |
| 2020-04-15 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 2,500 | $30.00 |
| 2020-04-02 | FONTEYNE, PAUL R. | Director | ストックオプション | 購入 | 37,500 | $0.00 |
| 2020-03-25 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 2,500 | $30.00 |
| 2020-03-25 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 2,500 | $2.67 |
| 2020-03-25 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 2,500 | $0.00 |
| 2020-03-17 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 30,637 | $2.14 |
| 2020-03-17 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 売却 | 30,637 | $0.00 |
| 2020-03-16 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 2,108 | $20.73 |
| 2020-03-16 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 700 | $22.29 |
| 2020-03-16 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 12,060 | $20.69 |
| 2020-03-16 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 15,065 | $21.58 |
| 2020-03-16 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 3,212 | $22.28 |
| 2020-03-16 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 300 | $23.86 |
| 2020-03-16 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 2,192 | $21.57 |
| 2020-03-16 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 売却 | 30,637 | $0.00 |
| 2020-03-16 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 30,637 | $2.14 |
| 2020-03-10 | DESCHATELETS, PASCAL | Chief Operating Officer | 普通株式 | 売却 | 161,656 | $0.00 |
| 2020-02-19 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 30,637 | $2.14 |
| 2020-02-19 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 売却 | 30,637 | $0.00 |
| 2020-02-18 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 売却 | 30,637 | $0.00 |
| 2020-02-18 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $40.67 |
| 2020-02-18 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 30,637 | $40.66 |
| 2020-02-18 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 30,637 | $2.14 |
| 2020-02-14 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 2,500 | $42.35 |
| 2020-02-14 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 2,500 | $2.67 |
| 2020-02-14 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 2,500 | $0.00 |
| 2020-02-13 | DESCHATELETS, PASCAL | Chief Operating Officer | 普通株式 | 購入 | 117,205 | $2.14 |
| 2020-02-13 | DESCHATELETS, PASCAL | Chief Operating Officer | 普通株式 | 売却 | 55,398 | $40.98 |
| 2020-02-13 | DESCHATELETS, PASCAL | Chief Operating Officer | ストックオプション | 売却 | 117,205 | $0.00 |
| 2020-02-12 | DESCHATELETS, PASCAL | Chief Operating Officer | 普通株式 | 購入 | 117,206 | $2.14 |
| 2020-02-12 | DESCHATELETS, PASCAL | Chief Operating Officer | 普通株式 | 売却 | 52,075 | $42.80 |
| 2020-02-12 | DESCHATELETS, PASCAL | Chief Operating Officer | ストックオプション | 売却 | 117,206 | $0.00 |
| 2020-02-10 | SCHEIBLER, LUKAS | See Remarks | 普通株式 | 購入 | 9,375 | $0.00 |
| 2020-02-10 | WATSON, DAVID O. | General Counsel | ストックオプション | 売却 | 7,505 | $0.00 |
| 2020-02-10 | WATSON, DAVID O. | General Counsel | ストックオプション | 購入 | 38,250 | $0.00 |
| 2020-02-10 | WATSON, DAVID O. | General Counsel | 普通株式 | 購入 | 7,505 | $2.67 |
| 2020-02-10 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 5,000 | $44.50 |
| 2020-02-10 | WATSON, DAVID O. | General Counsel | 普通株式 | 購入 | 6,375 | $0.00 |
| 2020-02-10 | GROSSI, FEDERICO | See Remarks | ストックオプション | 購入 | 56,250 | $0.00 |
| 2020-02-10 | GROSSI, FEDERICO | See Remarks | 普通株式 | 購入 | 9,375 | $0.00 |
| 2020-02-10 | SADR, AHMAD | See Remarks | ストックオプション | 購入 | 16,350 | $0.00 |
| 2020-02-10 | SADR, AHMAD | See Remarks | 普通株式 | 購入 | 2,725 | $0.00 |
| 2020-02-10 | LACKNER, THOMAS A. | See Remarks | ストックオプション | 購入 | 16,350 | $0.00 |
| 2020-02-10 | DESCHATELETS, PASCAL | Chief Operating Officer | 普通株式 | 購入 | 9,375 | $0.00 |
| 2020-02-10 | SCHEIBLER, LUKAS | See Remarks | ストックオプション | 購入 | 56,250 | $0.00 |
| 2020-02-10 | LACKNER, THOMAS A. | See Remarks | 普通株式 | 購入 | 2,725 | $0.00 |
| 2020-02-10 | PERRY, NICOLE D | Vice President - Finance | ストックオプション | 購入 | 15,000 | $0.00 |
| 2020-02-10 | PERRY, NICOLE D | Vice President - Finance | 普通株式 | 購入 | 2,500 | $0.00 |
| 2020-02-10 | CELONA, LUCIA | See Remarks | ストックオプション | 購入 | 31,275 | $0.00 |
| 2020-02-10 | CELONA, LUCIA | See Remarks | 普通株式 | 購入 | 5,213 | $0.00 |
| 2020-02-10 | TOWNSEND, ADAM J. | See Remarks | ストックオプション | 購入 | 56,250 | $0.00 |
| 2020-02-10 | TOWNSEND, ADAM J. | See Remarks | 普通株式 | 購入 | 9,375 | $0.00 |
| 2020-02-10 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 購入 | 206,250 | $0.00 |
| 2020-02-10 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 34,375 | $0.00 |
| 2020-02-10 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | ストックオプション | 購入 | 70,125 | $0.00 |
| 2020-02-10 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 購入 | 11,688 | $0.00 |
| 2020-02-10 | DESCHATELETS, PASCAL | Chief Operating Officer | ストックオプション | 購入 | 56,250 | $0.00 |
| 2020-01-27 | WATSON, DAVID O. | General Counsel | 普通株式 | 売却 | 3,000 | $40.47 |
| 2020-01-27 | WATSON, DAVID O. | General Counsel | 普通株式 | 購入 | 15,000 | $2.67 |
| 2020-01-27 | WATSON, DAVID O. | General Counsel | ストックオプション | 売却 | 15,000 | $0.00 |
| 2020-01-16 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 30,637 | $2.14 |
| 2020-01-16 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 売却 | 30,637 | $0.00 |
| 2020-01-15 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 売却 | 30,638 | $0.00 |
| 2020-01-15 | MACHIELS, ALEC | Director | ストックオプション | 売却 | 2,500 | $0.00 |
| 2020-01-15 | MACHIELS, ALEC | Director | 普通株式 | 売却 | 2,500 | $41.47 |
| 2020-01-15 | MACHIELS, ALEC | Director | 普通株式 | 購入 | 2,500 | $2.67 |
| 2020-01-15 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 30,638 | $2.14 |
| 2020-01-15 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $41.47 |
| 2020-01-15 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 4,562 | $42.55 |
| 2020-01-15 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 26,076 | $42.16 |
| 2020-01-13 | MORNINGSIDE, VENTURE INVESTMENTS LTD | 10% Owner | 普通株式 | 購入 | 540,540 | $37.00 |
| 2020-01-01 | DUNLOP, A. SINCLAIR | Director | ストックオプション | 購入 | 27,600 | $30.62 |
| 2020-01-01 | MACHIELS, ALEC | Director | ストックオプション | 購入 | 27,600 | $30.62 |
| 2020-01-01 | CHAN, GERALD | Director | ストックオプション | 購入 | 27,600 | $30.62 |
| 2020-01-01 | O'BRIEN, STEPHANIE MONAGHAN | Director | ストックオプション | 購入 | 27,600 | $30.62 |
| 2019-12-20 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 25,000 | $29.53 |
| 2019-12-19 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 31,000 | $29.51 |
| 2019-12-19 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 54,110 | $28.99 |
| 2019-12-18 | DUNLOP, A. SINCLAIR | Director | 普通株式 | 売却 | 25,890 | $28.55 |
| 2019-12-16 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $27.95 |
| 2019-11-15 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $27.28 |
| 2019-10-15 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 3,524 | $26.61 |
| 2019-10-15 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 1,476 | $25.59 |
| 2019-09-25 | DESCHATELETS, PASCAL | Chief Operating Officer | 普通株式 | 売却 | 1,010 | $25.64 |
| 2019-09-25 | DESCHATELETS, PASCAL | Chief Operating Officer | 普通株式 | 売却 | 20,531 | $25.24 |
| 2019-09-24 | DESCHATELETS, PASCAL | Chief Operating Officer | 普通株式 | 売却 | 1,295 | $24.96 |
| 2019-09-24 | DESCHATELETS, PASCAL | Chief Operating Officer | 普通株式 | 売却 | 20,307 | $24.56 |
| 2019-09-23 | DESCHATELETS, PASCAL | Chief Operating Officer | 普通株式 | 売却 | 100 | $25.53 |
| 2019-09-23 | DESCHATELETS, PASCAL | Chief Operating Officer | 普通株式 | 売却 | 20,758 | $25.07 |
| 2019-09-16 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 260 | $27.17 |
| 2019-09-16 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 4,740 | $26.56 |
| 2019-08-29 | SULLIVAN, TIMOTHY EUGENE | Chief Financial Officer | 普通株式 | 購入 | 11,699 | $29.71 |
| 2019-08-23 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 売却 | 37,505 | $0.00 |
| 2019-08-23 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 37,505 | $2.67 |
| 2019-08-15 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 7,754 | $26.74 |
| 2019-08-15 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $2.14 |
| 2019-08-15 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 売却 | 10,000 | $0.00 |
| 2019-08-15 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 売却 | 2,246 | $27.00 |
| 2019-08-07 | WATSON, DAVID O. | General Counsel | ストックオプション | 売却 | 5,000 | $0.00 |
| 2019-08-07 | WATSON, DAVID O. | General Counsel | 普通株式 | 購入 | 5,000 | $2.67 |
| 2019-06-27 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | ストックオプション | 売却 | 275,000 | $0.00 |
| 2019-06-27 | FRANCOIS, CEDRIC | Director, Chief Executive Officer | 普通株式 | 購入 | 275,000 | $2.14 |
| 2019-03-11 | MORNINGSIDE, VENTURE INVESTMENTS LTD | 10% Owner | 普通株式 | 購入 | 441,176 | $17.00 |
売上・収益性
売上高（直近12ヶ月）
$100,378万ドル
一株あたり売上高（直近12ヶ月）
$7.96
売上総利益（直近12ヶ月）
$60,569万ドル
営業利益（EBITDA：減価償却前）
$5,698万ドル
利益率
2.23%
営業利益率（直近12ヶ月）
-25.6%
配当・収入
配当金額（1株あたり）
$None
配当利回り
0%
支払日
None
権利落ち日
None
バリュエーション指標
株価収益率（PER）
226.61倍
実績PER
226.61倍
予想PER
46.3倍
株価収益成長率（PEG）
None
株価売上高倍率（直近12ヶ月）
5.2倍
株価純資産倍率 (PBR)
14.09倍
1株当たり純資産（BPS）
$2.92
企業価値倍率（EV）
EV/売上高倍率
5.2倍
EV/EBITDA倍率
74.62倍
投資リターン
総資産利益率（直近12ヶ月）
3.53%
自己資本利益率（直近12ヶ月）
7.48%
リターン分析
| 日数 | リターンレンジ | リターン中央値 | 累積リターン | 分散（バリアンス） | 標準偏差 | 最大下落率 | 最大下落期間 | SPYとの相関係数 | ||
|---|---|---|---|---|---|---|---|---|---|---|
| 15日間 | -0.0983% | 0.5444% | 0.086% | 1.5287% | 4.002309130323481e-06 | 0.0020005771992911148 | -0.1229% | 2日 | -0.11805115128580293 | |
| 30日間 | -4.9416% | 135.4008% | 0.0554% | 116.5872% | 0.0803162253896911 | 0.28340117393844916 | -5.1934% | 2日 | -0.036774863053121824 | |
| 90日間 | -5.1084% | 135.4008% | -0.1816% | 99.0745% | 0.029684829401807406 | 0.172292859404583 | -8.7345% | 7日 | -0.007319185720909317 |
損益計算書
会計期末日
2025-12-31
報告通貨
USD
売上高・粗利益
売上原価
営業経費
営業利益・税引前指標
売上高
$1,003,782,000
粗利益
$901,546,000
売上コスト
$102,236,000
商品・サービス原価
$102,236,000
販売管理費
$550,265,000
研究開発
$295,854,000
運営コスト
$846,119,000
減価償却
$None
減価償却・償却費
$1,558,000
営業利益
$55,427,000
営業利益EBIT
$68,437,000
償却前営業利益EBITA
$69,995,000
税引前利益
$24,110,000
利息・投資・その他営業外項目
税金関連
当期純・包括利益
純投資収益
$None
純金利収入
-$31,184,000
利息収入
$13,143,000
金利コスト
$44,327,000
利息・債務コスト
$None
非利息収益
$None
営業外収益（その他）
$None
法人税等
$1,722,000
継続事業純利益
$22,388,000
純利益
$22,388,000
税引後包括利益
$None
貸借対照表
会計期末日
2025-12-31
報告通貨
USD
総資産
$1,075,257,000
現金及び現金同等物
$467,760,000
現金及び短期投資
$467,760,000
短期投資
$None
在庫資産
$142,556,000
流動売掛金（純額）
$366,221,000
その他流動資産
$38,303,000
流動資産合計
$1,014,840,000
有形固定資産
$None
減価償却累計額（PPE）
$None
無形資産
$None
無形資産（のれん除く）
$None
のれん（無形資産）
$None
投資
$None
長期投資
$None
その他固定資産
$None
固定資産合計
$60,417,000
総負債
$705,110,000
買掛金（短期）
$56,798,000
前受金
$None
流動債務
$None
短期借入金
$100,749,000
固定長期負債
$93,662,000
その他流動負債
$166,049,000
流動負債合計
$323,596,000
リース債務
$19,034,000
長期債務
$361,664,000
長期債務（流動外）
$None
短期・長期借入金合計
$486,307,000
その他固定負債
$7,903,000
固定負債合計
$381,514,000
純資産
$370,147,000
自己株式（金庫株）
$None
利益剰余金
-$3,012,978,000
普通株式
$12,000
発行済株式数（普通株）
$126,024,000
キャッシュフロー計算書
会計期末日
2025-12-31
報告通貨
USD
損益計算・収益性
営業活動
投資活動
損益
$None
純利益
$22,388,000
営業キャッシュフロー
$45,327,000
営業活動による支払い
$None
営業活動によるキャッシュフロー
$None
営業活動に関連する負債の増減額
$None
営業活動に関連する資産の増減額
$None
売掛金の増減額
$None
在庫資産の増減額
-$15,267,000
減価償却・減耗費・償却費
$1,558,000
投資活動によるキャッシュフロー
-$313,000
設備投資
$313,000
財務活動
資金・為替照合
財務活動によるキャッシュフロー
$8,884,000
短期融資回収金
$None
自社株買い支出（普通株）
$None
自社株買い支出（優先株）
$None
自社株買い支出
$None
配当支払い（普通株）
$None
配当支払い（優先株）
$None
配当支払い
$None
資金調達（普通株）
$None
資金調達（優先株）
$None
資金調達（長期債・資本証券）
$None
自社株売却による収益
$None
自社株再取得による収益
$None
現金及び現金同等物の増減額
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オンライン英会話DOJO
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