NVAX
ノババックス
Novavax Inc
株価・概要
$8.04
0.12 (1.4511%)
06:00AM 2026/05/02 (JST)
NASDAQ | USD
52週間レンジ
5.8
11.97
昨夜レンジ
7.86
8.08
前日終値
$7.93
出来高（数量）
3,006,559
ベータ値
2.648
50日移動平均値
$9.09
200日移動平均値
$8.20
1株あたりの利益（EPS）
2.58
予想PER（株価収益率）
2.585
配当金
$None
配当利回り
0%
インサイダー保有率
5.009%
機関投資家保有率
68.138%
NVAX - 会社概要
ノババックス社（Novavax, Inc.）は、メリーランド州ゲイザースバーグに本拠を置く、ワクチン開発の先駆的手法で知られる大手バイオテクノロジー企業です。同社は独自のタンパク質ベースのナノ粒子技術を活用し、先進的なCOVID-19ワクチン候補を含む強力なパイプラインを確立しており、世界的な健康課題の中で大きな注目を集めています。戦略的提携や革新的なヘルスソリューションへの取り組みは、公衆衛生に大きな影響を与える可能性を示しており、バイオテクノロジー分野に注目する機関投資家にとって魅力的な投資先となっています。
本社住所
21 FIRSTFIELD ROAD, GAITHERSBURG, MD, UNITED STATES, 20878
企業サイト
https://www.novavax.com
会計年度終了
December
最新四半期
2025-12-31
利益・成長性
1株あたりの利益（EPS）
$2.58
希薄化後1株当たり利益EPS（直近12ヶ月）
$2.58
四半期利益成長率（前年比）
-38.1%
四半期売上成長率（前年比）
66.6%
アナリスト予想・評価
目標株価
$14.00
強気
0
買い
5
ホールド
1
売り
1
弱気
2
EPS（1株当たり純利益）
| 7日前 | 30日前 | 60日前 | 90日前 | 予想レンジ | |||
|---|---|---|---|---|---|---|---|
配当履歴
| 権利落ち日 | 配当宣言日 | 権利確定日 | 配当金支払日 | 配当金額 |
|---|
株式分割
| 効力発生日 | 分割比率 |
|---|---|
| 2019-05-10 | 0.0500 |
インサイダーの売却・購入履歴
| 自社株取引日 | 役員・従業員名 | 役員・従業員の役職 | 株式の種類 | 売却／購入 | 株数 | 株価 |
|---|---|---|---|---|---|---|
| 2026-03-10 | SHIVER, JOHN W. | Director | 普通株式 | 購入 | 7,947 | $0.00 |
| 2026-03-10 | SHIVER, JOHN W. | Director | 譲渡制限付株式ユニット | 売却 | 7,947 | $0.00 |
| 2026-03-07 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 譲渡制限付株式ユニット | 売却 | 12,223 | $0.00 |
| 2026-03-07 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 普通株式 | 購入 | 12,223 | $0.00 |
| 2026-03-07 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 普通株式 | 売却 | 5,904 | $9.98 |
| 2026-03-03 | DRAGHIA-AKLI, RUXANDRA | EVP, Research & Development | 譲渡制限付株式ユニット | 売却 | 26,667 | $0.00 |
| 2026-03-03 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 普通株式 | 購入 | 43,167 | $0.00 |
| 2026-03-03 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 普通株式 | 売却 | 20,850 | $9.49 |
| 2026-03-03 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 譲渡制限付株式ユニット | 売却 | 43,167 | $0.00 |
| 2026-03-03 | JACOBS, JOHN C | Director, President and CEO | 普通株式 | 購入 | 150,167 | $0.00 |
| 2026-03-03 | JACOBS, JOHN C | Director, President and CEO | 普通株式 | 売却 | 69,288 | $9.49 |
| 2026-03-03 | JACOBS, JOHN C | Director, President and CEO | 譲渡制限付株式ユニット | 売却 | 150,167 | $0.00 |
| 2026-03-03 | O'HARA, ELAINE | EVP, Chief Strategy Officer | 普通株式 | 購入 | 56,334 | $0.00 |
| 2026-03-03 | O'HARA, ELAINE | EVP, Chief Strategy Officer | 普通株式 | 売却 | 22,429 | $9.49 |
| 2026-03-03 | O'HARA, ELAINE | EVP, Chief Strategy Officer | 譲渡制限付株式ユニット | 売却 | 56,334 | $0.00 |
| 2026-03-03 | CASEY, MARK J | EVP, Chief Legal Officer | 普通株式 | 購入 | 37,500 | $0.00 |
| 2026-03-03 | CASEY, MARK J | EVP, Chief Legal Officer | 普通株式 | 売却 | 11,378 | $9.49 |
| 2026-03-03 | CASEY, MARK J | EVP, Chief Legal Officer | 譲渡制限付株式ユニット | 売却 | 4,000 | $0.00 |
| 2026-03-03 | DRAGHIA-AKLI, RUXANDRA | EVP, Research & Development | 普通株式 | 購入 | 26,667 | $0.00 |
| 2026-03-03 | DRAGHIA-AKLI, RUXANDRA | EVP, Research & Development | 普通株式 | 売却 | 11,313 | $9.49 |
| 2026-03-02 | O'HARA, ELAINE | EVP, Chief Strategy Officer | ストックオプション | 購入 | 177,500 | $9.09 |
| 2026-03-02 | CASEY, MARK J | EVP, Chief Legal Officer | 譲渡制限付株式ユニット | 購入 | 101,000 | $0.00 |
| 2026-03-02 | CASEY, MARK J | EVP, Chief Legal Officer | 普通株式 | 購入 | 152,000 | $9.09 |
| 2026-03-02 | O'HARA, ELAINE | EVP, Chief Strategy Officer | ストックオプション | 購入 | 177,500 | $0.00 |
| 2026-03-02 | JACOBS, JOHN C | Director, President and CEO | ストックオプション | 購入 | 551,500 | $0.00 |
| 2026-03-02 | CASEY, MARK J | EVP, Chief Legal Officer | ストックオプション | 購入 | 152,000 | $0.00 |
| 2026-03-02 | DRAGHIA-AKLI, RUXANDRA | EVP, Research & Development | ストックオプション | 購入 | 139,500 | $0.00 |
| 2026-03-02 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | ストックオプション | 購入 | 194,000 | $0.00 |
| 2026-03-02 | DRAGHIA-AKLI, RUXANDRA | EVP, Research & Development | 普通株式 | 購入 | 139,500 | $9.09 |
| 2026-03-02 | DRAGHIA-AKLI, RUXANDRA | EVP, Research & Development | 譲渡制限付株式ユニット | 購入 | 93,000 | $0.00 |
| 2026-03-02 | JACOBS, JOHN C | Director, President and CEO | 譲渡制限付株式ユニット | 購入 | 367,500 | $0.00 |
| 2026-03-02 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 譲渡制限付株式ユニット | 購入 | 129,500 | $0.00 |
| 2026-03-02 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | ストックオプション | 購入 | 194,000 | $9.09 |
| 2026-03-02 | JACOBS, JOHN C | Director, President and CEO | ストックオプション | 購入 | 551,500 | $9.09 |
| 2026-03-02 | O'HARA, ELAINE | EVP, Chief Strategy Officer | 譲渡制限付株式ユニット | 購入 | 118,000 | $0.00 |
| 2026-03-01 | O'HARA, ELAINE | EVP, Chief Strategy Officer | 譲渡制限付株式ユニット | 売却 | 19,600 | $0.00 |
| 2026-03-01 | O'HARA, ELAINE | EVP, Chief Strategy Officer | 普通株式 | 購入 | 40,000 | $0.00 |
| 2026-03-01 | O'HARA, ELAINE | EVP, Chief Strategy Officer | 普通株式 | 売却 | 5,375 | $10.14 |
| 2026-03-01 | O'HARA, ELAINE | EVP, Chief Strategy Officer | 普通株式 | 購入 | 19,600 | $0.00 |
| 2026-03-01 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 譲渡制限付株式ユニット | 売却 | 58,666 | $0.00 |
| 2026-03-01 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 普通株式 | 売却 | 28,366 | $10.14 |
| 2026-03-01 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 普通株式 | 購入 | 58,666 | $0.00 |
| 2026-03-01 | JACOBS, JOHN C | Director, President and CEO | 譲渡制限付株式ユニット | 売却 | 83,333 | $0.00 |
| 2026-03-01 | JACOBS, JOHN C | Director, President and CEO | 普通株式 | 売却 | 38,450 | $10.14 |
| 2026-03-01 | JACOBS, JOHN C | Director, President and CEO | 普通株式 | 購入 | 83,333 | $0.00 |
| 2026-03-01 | CASEY, MARK J | EVP, Chief Legal Officer | 譲渡制限付株式ユニット | 売却 | 4,000 | $0.00 |
| 2026-03-01 | CASEY, MARK J | EVP, Chief Legal Officer | 普通株式 | 売却 | 1,214 | $10.14 |
| 2026-03-01 | CASEY, MARK J | EVP, Chief Legal Officer | 普通株式 | 購入 | 4,000 | $0.00 |
| 2026-03-01 | O'HARA, ELAINE | EVP, Chief Strategy Officer | 譲渡制限付株式ユニット | 売却 | 40,000 | $0.00 |
| 2026-03-01 | O'HARA, ELAINE | EVP, Chief Strategy Officer | 普通株式 | 売却 | 10,969 | $10.14 |
| 2026-01-23 | JACOBS, JOHN C | Director, President and CEO | 譲渡制限付株式ユニット | 売却 | 83,197 | $0.00 |
| 2026-01-23 | JACOBS, JOHN C | Director, President and CEO | 普通株式 | 購入 | 83,197 | $0.00 |
| 2026-01-23 | JACOBS, JOHN C | Director, President and CEO | 普通株式 | 売却 | 39,132 | $9.17 |
| 2025-12-11 | CASEY, MARK J | EVP, Chief Legal Officer | 普通株式 | 購入 | 41,899 | $0.00 |
| 2025-12-11 | CASEY, MARK J | EVP, Chief Legal Officer | 譲渡制限付株式ユニット | 売却 | 41,899 | $0.00 |
| 2025-12-11 | CASEY, MARK J | EVP, Chief Legal Officer | 普通株式 | 売却 | 12,713 | $6.69 |
| 2025-11-11 | DRAGHIA-AKLI, RUXANDRA | Section 16 | 普通株式 | 購入 | 14,257 | $0.00 |
| 2025-11-11 | DRAGHIA-AKLI, RUXANDRA | Section 16 | 普通株式 | 売却 | 6,048 | $7.40 |
| 2025-11-11 | DRAGHIA-AKLI, RUXANDRA | Section 16 | 譲渡制限付株式ユニット | 売却 | 14,257 | $0.00 |
| 2025-10-29 | RODGERS, RICHARD J | Director | 普通株式 | 購入 | 3,800 | $ |
| 2025-10-29 | RODGERS, RICHARD J | Director | 譲渡制限付株式ユニット | 売却 | 3,800 | $0.00 |
| 2025-06-20 | RODGERS, RICHARD J | Director | 譲渡制限付株式ユニット | 購入 | 18,884 | $0.00 |
| 2025-06-20 | RODGERS, RICHARD J | Director | ストックオプション | 購入 | 28,326 | $6.42 |
| 2025-06-20 | MCGLYNN, MARGARET G | Director | 譲渡制限付株式ユニット | 購入 | 18,884 | $0.00 |
| 2025-06-20 | MCGLYNN, MARGARET G | Director | ストックオプション | 購入 | 28,326 | $6.42 |
| 2025-06-20 | ALTON, GREGG H | Director | 譲渡制限付株式ユニット | 購入 | 18,884 | $0.00 |
| 2025-06-20 | ALTON, GREGG H | Director | ストックオプション | 購入 | 28,326 | $6.42 |
| 2025-06-20 | DOUGLAS, RICHARD | Director | 譲渡制限付株式ユニット | 購入 | 18,884 | $0.00 |
| 2025-06-20 | DOUGLAS, RICHARD | Director | ストックオプション | 購入 | 28,326 | $6.42 |
| 2025-06-20 | KING, RACHEL K. | Director | 譲渡制限付株式ユニット | 購入 | 18,884 | $0.00 |
| 2025-06-20 | KING, RACHEL K. | Director | ストックオプション | 購入 | 28,326 | $6.42 |
| 2025-06-20 | MOTT, DAVID M | Director | 譲渡制限付株式ユニット | 購入 | 18,884 | $0.00 |
| 2025-06-20 | MOTT, DAVID M | Director | ストックオプション | 購入 | 28,326 | $6.42 |
| 2025-06-12 | ALTON, GREGG H | Director | 普通株式 | 購入 | 10,420 | $0.00 |
| 2025-06-12 | MCGLYNN, MARGARET G | Director | 譲渡制限付株式ユニット | 売却 | 10,420 | $0.00 |
| 2025-06-12 | MCGLYNN, MARGARET G | Director | 普通株式 | 購入 | 10,420 | $0.00 |
| 2025-06-12 | DOUGLAS, RICHARD | Director | 譲渡制限付株式ユニット | 売却 | 10,420 | $0.00 |
| 2025-06-12 | DOUGLAS, RICHARD | Director | 普通株式 | 購入 | 10,420 | $0.00 |
| 2025-06-12 | MOTT, DAVID M | Director | 譲渡制限付株式ユニット | 売却 | 10,420 | $0.00 |
| 2025-06-12 | MOTT, DAVID M | Director | 普通株式 | 購入 | 10,420 | $0.00 |
| 2025-06-12 | RODGERS, RICHARD J | Director | 譲渡制限付株式ユニット | 売却 | 10,420 | $0.00 |
| 2025-06-12 | RODGERS, RICHARD J | Director | 普通株式 | 購入 | 10,420 | $0.00 |
| 2025-06-12 | KING, RACHEL K. | Director | 譲渡制限付株式ユニット | 売却 | 10,420 | $0.00 |
| 2025-06-12 | KING, RACHEL K. | Director | 普通株式 | 購入 | 10,420 | $0.00 |
| 2025-06-12 | ALTON, GREGG H | Director | 譲渡制限付株式ユニット | 売却 | 10,420 | $0.00 |
| 2025-04-25 | NEWTON, CHARLES W. | Director | ストックオプション | 購入 | 42,840 | $0.00 |
| 2025-04-25 | NEWTON, CHARLES W. | Director | 譲渡制限付株式ユニット | 購入 | 28,560 | $0.00 |
| 2025-03-10 | SHIVER, JOHN W. | Director | ストックオプション | 購入 | 35,770 | $0.00 |
| 2025-03-10 | SHIVER, JOHN W. | Director | 譲渡制限付株式ユニット | 購入 | 23,840 | $0.00 |
| 2025-03-07 | TRIZZINO, JOHN | President and COO | 普通株式 | 購入 | 28,890 | $0.00 |
| 2025-03-07 | TRIZZINO, JOHN | President and COO | 普通株式 | 売却 | 13,954 | $8.34 |
| 2025-03-07 | TRIZZINO, JOHN | President and COO | 譲渡制限付株式ユニット | 売却 | 28,890 | $0.00 |
| 2025-03-07 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 譲渡制限付株式ユニット | 売却 | 12,223 | $0.00 |
| 2025-03-07 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 普通株式 | 売却 | 5,904 | $8.34 |
| 2025-03-07 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 普通株式 | 購入 | 12,223 | $0.00 |
| 2025-03-03 | CASEY, MARK J | EVP, Chief Legal Officer | 譲渡制限付株式ユニット | 購入 | 112,500 | $0.00 |
| 2025-03-03 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 譲渡制限付株式ユニット | 購入 | 129,500 | $0.00 |
| 2025-03-03 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | ストックオプション | 購入 | 194,500 | $7.87 |
| 2025-03-03 | O'HARA, ELAINE | EVP, Chief Strategy Officer | 譲渡制限付株式ユニット | 購入 | 169,000 | $0.00 |
| 2025-03-03 | CASEY, MARK J | EVP, Chief Legal Officer | ストックオプション | 購入 | 169,000 | $7.87 |
| 2025-03-03 | O'HARA, ELAINE | EVP, Chief Strategy Officer | ストックオプション | 購入 | 253,500 | $7.87 |
| 2025-03-03 | JACOBS, JOHN C | Director, President and CEO | 譲渡制限付株式ユニット | 購入 | 450,500 | $0.00 |
| 2025-03-03 | JACOBS, JOHN C | Director, President and CEO | ストックオプション | 購入 | 676,000 | $7.87 |
| 2025-03-03 | DRAGHIA-AKLI, RUXANDRA | Section 16 | 譲渡制限付株式ユニット | 購入 | 80,000 | $0.00 |
| 2025-03-03 | DRAGHIA-AKLI, RUXANDRA | Section 16 | ストックオプション | 購入 | 120,000 | $7.87 |
| 2025-03-01 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 譲渡制限付株式ユニット | 売却 | 58,667 | $0.00 |
| 2025-03-01 | JACOBS, JOHN C | Director, President and CEO | 普通株式 | 売却 | 38,451 | $8.33 |
| 2025-03-01 | JACOBS, JOHN C | Director, President and CEO | 譲渡制限付株式ユニット | 売却 | 83,334 | $0.00 |
| 2025-03-01 | O'HARA, ELAINE | EVP, Chief Strategy Officer | 普通株式 | 購入 | 19,600 | $0.00 |
| 2025-03-01 | O'HARA, ELAINE | EVP, Chief Strategy Officer | 普通株式 | 購入 | 40,000 | $0.00 |
| 2025-03-01 | O'HARA, ELAINE | EVP, Chief Strategy Officer | 普通株式 | 売却 | 5,375 | $8.33 |
| 2025-03-01 | O'HARA, ELAINE | EVP, Chief Strategy Officer | 普通株式 | 売却 | 10,969 | $8.33 |
| 2025-03-01 | O'HARA, ELAINE | EVP, Chief Strategy Officer | 譲渡制限付株式ユニット | 売却 | 19,600 | $0.00 |
| 2025-03-01 | O'HARA, ELAINE | EVP, Chief Strategy Officer | 譲渡制限付株式ユニット | 売却 | 40,000 | $0.00 |
| 2025-03-01 | CASEY, MARK J | EVP, Chief Legal Officer | 普通株式 | 売却 | 1,214 | $8.33 |
| 2025-03-01 | CASEY, MARK J | EVP, Chief Legal Officer | 普通株式 | 購入 | 4,000 | $0.00 |
| 2025-03-01 | TRIZZINO, JOHN | President and COO | 譲渡制限付株式ユニット | 売却 | 48,000 | $0.00 |
| 2025-03-01 | TRIZZINO, JOHN | President and COO | 普通株式 | 売却 | 23,185 | $8.33 |
| 2025-03-01 | TRIZZINO, JOHN | President and COO | 普通株式 | 購入 | 48,000 | $0.00 |
| 2025-03-01 | CASEY, MARK J | EVP, Chief Legal Officer | 譲渡制限付株式ユニット | 売却 | 4,000 | $0.00 |
| 2025-03-01 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 普通株式 | 購入 | 58,667 | $0.00 |
| 2025-03-01 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 普通株式 | 売却 | 28,337 | $8.33 |
| 2025-03-01 | JACOBS, JOHN C | Director, President and CEO | 普通株式 | 購入 | 83,334 | $0.00 |
| 2025-01-23 | JACOBS, JOHN C | Director, President and CEO | 普通株式 | 売却 | 38,873 | $9.55 |
| 2025-01-23 | JACOBS, JOHN C | Director, President and CEO | 譲渡制限付株式ユニット | 売却 | 83,196 | $0.00 |
| 2025-01-23 | JACOBS, JOHN C | Director, President and CEO | 普通株式 | 購入 | 83,196 | $0.00 |
| 2024-12-31 | ALTON, GREGG H | Director | 普通株式 | 購入 | 1,982 | $8.61 |
| 2024-12-31 | MCGLYNN, MARGARET G | Director | 普通株式 | 購入 | 1,178 | $8.61 |
| 2024-12-31 | YOUNG, JAMES F | Director | 普通株式 | 売却 | 5,400 | $8.00 |
| 2024-12-31 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 普通株式 | 購入 | 35,000 | $0.00 |
| 2024-12-31 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 普通株式 | 売却 | 16,906 | $8.04 |
| 2024-12-31 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 譲渡制限付株式ユニット | 売却 | 35,000 | $0.00 |
| 2024-12-24 | YOUNG, JAMES F | Director | 普通株式 | 売却 | 4,600 | $8.48 |
| 2024-12-13 | KING, RACHEL K. | Director | 普通株式 | 売却 | 4,150 | $9.02 |
| 2024-12-11 | CASEY, MARK J | EVP, Chief Legal Officer | 普通株式 | 購入 | 41,900 | $0.00 |
| 2024-12-11 | CASEY, MARK J | EVP, Chief Legal Officer | 譲渡制限付株式ユニット | 売却 | 41,900 | $0.00 |
| 2024-12-11 | CASEY, MARK J | EVP, Chief Legal Officer | 普通株式 | 売却 | 12,713 | $8.82 |
| 2024-11-11 | DRAGHIA-AKLI, RUXANDRA | Section 16 | 譲渡制限付株式ユニット | 購入 | 42,770 | $0.00 |
| 2024-11-11 | DRAGHIA-AKLI, RUXANDRA | Section 16 | ストックオプション | 購入 | 64,150 | $9.01 |
| 2024-10-29 | RODGERS, RICHARD J | Director | 譲渡制限付株式ユニット | 売却 | 3,800 | $0.00 |
| 2024-10-29 | RODGERS, RICHARD J | Director | 普通株式 | 購入 | 3,800 | $0.00 |
| 2024-09-30 | MCGLYNN, MARGARET G | Director | 普通株式 | 購入 | 778 | $12.77 |
| 2024-09-30 | ALTON, GREGG H | Director | 普通株式 | 購入 | 1,311 | $12.77 |
| 2024-08-19 | TRIZZINO, JOHN | EVP, CCO and CBO | 譲渡制限付株式ユニット | 売却 | 655 | $0.00 |
| 2024-08-19 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 購入 | 655 | $0.00 |
| 2024-08-19 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 317 | $13.90 |
| 2024-08-16 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 普通株式 | 売却 | 1,223 | $12.96 |
| 2024-08-16 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 普通株式 | 購入 | 2,367 | $12.96 |
| 2024-08-16 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 譲渡制限付株式ユニット | 売却 | 2,367 | $0.00 |
| 2024-06-30 | ALTON, GREGG H | Director | 普通株式 | 購入 | 1,202 | $13.93 |
| 2024-06-30 | MCGLYNN, MARGARET G | Director | 普通株式 | 購入 | 713 | $13.93 |
| 2024-06-21 | YOUNG, JAMES F | Director | 普通株式 | 売却 | 7,500 | $14.09 |
| 2024-06-18 | YOUNG, JAMES F | Director | 普通株式 | 売却 | 6,393 | $13.62 |
| 2024-06-18 | YOUNG, JAMES F | Director | 普通株式 | 売却 | 1,107 | $14.28 |
| 2024-06-17 | DUBOVSKY, FILIP | President, R&D | ストックオプション | 売却 | 12,500 | $6.09 |
| 2024-06-17 | DUBOVSKY, FILIP | President, R&D | ストックオプション | 売却 | 1,404 | $6.97 |
| 2024-06-17 | DUBOVSKY, FILIP | President, R&D | 普通株式 | 売却 | 12,500 | $14.46 |
| 2024-06-17 | DUBOVSKY, FILIP | President, R&D | 普通株式 | 売却 | 1,404 | $14.54 |
| 2024-06-17 | DUBOVSKY, FILIP | President, R&D | 普通株式 | 購入 | 12,500 | $6.09 |
| 2024-06-17 | DUBOVSKY, FILIP | President, R&D | 普通株式 | 購入 | 1,404 | $6.97 |
| 2024-06-12 | ALTON, GREGG H | Director | ストックオプション | 購入 | 15,630 | $15.86 |
| 2024-06-12 | ALTON, GREGG H | Director | 普通株式 | 購入 | 6,670 | $0.00 |
| 2024-06-12 | MCGLYNN, MARGARET G | Director | 譲渡制限付株式ユニット | 購入 | 10,420 | $0.00 |
| 2024-06-12 | MCGLYNN, MARGARET G | Director | ストックオプション | 購入 | 15,630 | $15.86 |
| 2024-06-12 | MCGLYNN, MARGARET G | Director | 譲渡制限付株式ユニット | 売却 | 6,670 | $0.00 |
| 2024-06-12 | MCGLYNN, MARGARET G | Director | 普通株式 | 購入 | 6,670 | $0.00 |
| 2024-06-12 | ALTON, GREGG H | Director | 譲渡制限付株式ユニット | 売却 | 6,670 | $0.00 |
| 2024-06-12 | YOUNG, JAMES F | Director | 譲渡制限付株式ユニット | 購入 | 10,420 | $0.00 |
| 2024-06-12 | YOUNG, JAMES F | Director | ストックオプション | 購入 | 15,630 | $15.86 |
| 2024-06-12 | YOUNG, JAMES F | Director | 譲渡制限付株式ユニット | 売却 | 6,670 | $0.00 |
| 2024-06-12 | YOUNG, JAMES F | Director | 普通株式 | 購入 | 6,670 | $0.00 |
| 2024-06-12 | RODGERS, RICHARD J | Director | 譲渡制限付株式ユニット | 購入 | 10,420 | $0.00 |
| 2024-06-12 | RODGERS, RICHARD J | Director | ストックオプション | 購入 | 15,630 | $15.86 |
| 2024-06-12 | RODGERS, RICHARD J | Director | 譲渡制限付株式ユニット | 売却 | 6,670 | $0.00 |
| 2024-06-12 | RODGERS, RICHARD J | Director | 普通株式 | 購入 | 6,670 | $0.00 |
| 2024-06-12 | MOTT, DAVID M | Director | 譲渡制限付株式ユニット | 購入 | 10,420 | $0.00 |
| 2024-06-12 | MOTT, DAVID M | Director | ストックオプション | 購入 | 15,630 | $15.86 |
| 2024-06-12 | KING, RACHEL K. | Director | 普通株式 | 購入 | 6,670 | $0.00 |
| 2024-06-12 | KING, RACHEL K. | Director | 譲渡制限付株式ユニット | 売却 | 6,670 | $0.00 |
| 2024-06-12 | MOTT, DAVID M | Director | 譲渡制限付株式ユニット | 売却 | 6,670 | $0.00 |
| 2024-06-12 | MOTT, DAVID M | Director | 普通株式 | 購入 | 6,670 | $0.00 |
| 2024-06-12 | KING, RACHEL K. | Director | 譲渡制限付株式ユニット | 購入 | 10,420 | $0.00 |
| 2024-06-12 | KING, RACHEL K. | Director | ストックオプション | 購入 | 15,630 | $15.86 |
| 2024-06-12 | DOUGLAS, RICHARD | Director | 譲渡制限付株式ユニット | 購入 | 10,420 | $0.00 |
| 2024-06-12 | DOUGLAS, RICHARD | Director | ストックオプション | 購入 | 15,630 | $15.86 |
| 2024-06-12 | DOUGLAS, RICHARD | Director | 譲渡制限付株式ユニット | 売却 | 6,670 | $0.00 |
| 2024-06-12 | DOUGLAS, RICHARD | Director | 普通株式 | 購入 | 6,670 | $0.00 |
| 2024-06-12 | ALTON, GREGG H | Director | 譲渡制限付株式ユニット | 購入 | 10,420 | $0.00 |
| 2024-05-14 | DUBOVSKY, FILIP | President, R&D | ストックオプション | 売却 | 19,652 | $0.00 |
| 2024-05-14 | DUBOVSKY, FILIP | President, R&D | 普通株式 | 購入 | 19,652 | $6.97 |
| 2024-05-14 | DUBOVSKY, FILIP | President, R&D | 普通株式 | 売却 | 47,312 | $13.90 |
| 2024-03-31 | MCGLYNN, MARGARET G | Director | 普通株式 | 購入 | 2,029 | $4.90 |
| 2024-03-31 | ALTON, GREGG H | Director | 普通株式 | 購入 | 3,420 | $4.90 |
| 2024-03-10 | DUBOVSKY, FILIP | President, R&D | 普通株式 | 売却 | 2,597 | $5.45 |
| 2024-03-10 | DUBOVSKY, FILIP | President, R&D | 普通株式 | 購入 | 5,376 | $ |
| 2024-03-10 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 譲渡制限付株式ユニット | 売却 | 4,608 | $0.00 |
| 2024-03-10 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 普通株式 | 売却 | 2,226 | $5.45 |
| 2024-03-10 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 普通株式 | 購入 | 4,608 | $ |
| 2024-03-10 | TRIZZINO, JOHN | President and COO | 譲渡制限付株式ユニット | 売却 | 4,608 | $0.00 |
| 2024-03-10 | TRIZZINO, JOHN | President and COO | 普通株式 | 売却 | 2,226 | $5.45 |
| 2024-03-10 | TRIZZINO, JOHN | President and COO | 普通株式 | 購入 | 4,608 | $ |
| 2024-03-10 | DUBOVSKY, FILIP | President, R&D | 譲渡制限付株式ユニット | 売却 | 5,376 | $0.00 |
| 2024-03-07 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 普通株式 | 購入 | 12,224 | $ |
| 2024-03-07 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 13,955 | $5.61 |
| 2024-03-07 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 購入 | 28,890 | $ |
| 2024-03-07 | DUBOVSKY, FILIP | President, R&D | 譲渡制限付株式ユニット | 売却 | 19,444 | $0.00 |
| 2024-03-07 | DUBOVSKY, FILIP | President, R&D | 普通株式 | 売却 | 9,392 | $5.61 |
| 2024-03-07 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 譲渡制限付株式ユニット | 売却 | 12,224 | $0.00 |
| 2024-03-07 | DUBOVSKY, FILIP | President, R&D | 普通株式 | 購入 | 19,444 | $ |
| 2024-03-07 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 普通株式 | 売却 | 5,905 | $5.61 |
| 2024-03-07 | TRIZZINO, JOHN | EVP, CCO and CBO | 譲渡制限付株式ユニット | 売却 | 28,890 | $0.00 |
| 2024-03-01 | JACOBS, JOHN C | Director, President and CEO | ストックオプション | 購入 | 500,000 | $0.00 |
| 2024-03-01 | TRIZZINO, JOHN | EVP, CCO and CBO | 譲渡制限付株式ユニット | 購入 | 144,000 | $0.00 |
| 2024-03-01 | O'HARA, ELAINE | EVP, Chief Strategy Officer | 譲渡制限付株式ユニット | 購入 | 120,000 | $0.00 |
| 2024-03-01 | KELLY, JAMES PATRICK | EVP, CFO & Treasurer | 譲渡制限付株式ユニット | 購入 | 176,000 | $0.00 |
| 2024-03-01 | DUBOVSKY, FILIP | President, R&D | 譲渡制限付株式ユニット | 購入 | 144,000 | $0.00 |
| 2024-03-01 | CASEY, MARK J | EVP, CLO & Corporate Secretary | 譲渡制限付株式ユニット | 購入 | 12,000 | $0.00 |
| 2024-03-01 | JACOBS, JOHN C | Director, President and CEO | 譲渡制限付株式ユニット | 購入 | 250,000 | $0.00 |
| 2024-03-01 | O'HARA, ELAINE | EVP, Chief Strategy Officer | 普通株式 | 購入 | 19,600 | $5.39 |
| 2024-03-01 | O'HARA, ELAINE | EVP, Chief Strategy Officer | 普通株式 | 売却 | 5,375 | $5.39 |
| 2024-03-01 | O'HARA, ELAINE | EVP, Chief Strategy Officer | 譲渡制限付株式ユニット | 売却 | 19,600 | $0.00 |
| 2024-01-23 | JACOBS, JOHN C | Director, President and CEO | 普通株式 | 購入 | 83,197 | $ |
| 2024-01-23 | JACOBS, JOHN C | Director, President and CEO | 普通株式 | 売却 | 40,093 | $4.26 |
| 2024-01-23 | JACOBS, JOHN C | Director, President and CEO | 譲渡制限付株式ユニット | 売却 | 83,197 | $0.00 |
| 2023-12-14 | DUBOVSKY, FILIP | President, R&D | 譲渡制限付株式ユニット | 売却 | 2,833 | $0.00 |
| 2023-12-14 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 700 | $5.69 |
| 2023-12-14 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 2,100 | $ |
| 2023-12-14 | TRIZZINO, JOHN | EVP, CCO and CBO | 譲渡制限付株式ユニット | 売却 | 1,600 | $0.00 |
| 2023-12-14 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 773 | $5.69 |
| 2023-12-14 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 購入 | 1,600 | $ |
| 2023-12-14 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 譲渡制限付株式ユニット | 売却 | 2,100 | $0.00 |
| 2023-12-14 | DUBOVSKY, FILIP | President, R&D | 普通株式 | 売却 | 1,368 | $5.69 |
| 2023-12-14 | DUBOVSKY, FILIP | President, R&D | 普通株式 | 購入 | 2,833 | $5.69 |
| 2023-12-11 | CASEY, MARK J | EVP, Chief Legal Officer | 譲渡制限付株式ユニット | 購入 | 125,698 | $0.00 |
| 2023-12-11 | CASEY, MARK J | EVP, Chief Legal Officer | ストックオプション | 購入 | 144,694 | $0.00 |
| 2023-11-05 | DUBOVSKY, FILIP | President, R&D | 譲渡制限付株式ユニット | 売却 | 1,400 | $0.00 |
| 2023-11-05 | DUBOVSKY, FILIP | President, R&D | 普通株式 | 購入 | 1,400 | $7.06 |
| 2023-11-05 | DUBOVSKY, FILIP | President, R&D | 普通株式 | 売却 | 677 | $7.06 |
| 2023-10-29 | RODGERS, RICHARD J | Director | 普通株式 | 購入 | 3,800 | $ |
| 2023-10-29 | RODGERS, RICHARD J | Director | 譲渡制限付株式ユニット | 売却 | 3,800 | $0.00 |
| 2023-09-16 | DUBOVSKY, FILIP | President, R&D | 普通株式 | 売却 | 6,108 | $7.71 |
| 2023-09-16 | DUBOVSKY, FILIP | President, R&D | 普通株式 | 購入 | 12,644 | $7.71 |
| 2023-09-16 | DUBOVSKY, FILIP | President, R&D | 譲渡制限付株式ユニット | 売却 | 12,644 | $0.00 |
| 2023-09-12 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 譲渡制限付株式ユニット | 売却 | 35,000 | $0.00 |
| 2023-08-19 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 317 | $7.14 |
| 2023-08-19 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 購入 | 655 | $ |
| 2023-08-19 | TRIZZINO, JOHN | EVP, CCO and CBO | 譲渡制限付株式ユニット | 売却 | 655 | $0.00 |
| 2023-08-16 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 普通株式 | 購入 | 2,366 | $ |
| 2023-08-16 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 普通株式 | 売却 | 1,143 | $7.13 |
| 2023-08-16 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 譲渡制限付株式ユニット | 売却 | 2,366 | $0.00 |
| 2023-06-25 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 譲渡制限付株式ユニット | 売却 | 833 | $0.00 |
| 2023-06-25 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 833 | $ |
| 2023-06-25 | TRIZZINO, JOHN | EVP, CCO and CBO | 譲渡制限付株式ユニット | 売却 | 833 | $0.00 |
| 2023-06-25 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 購入 | 833 | $ |
| 2023-06-25 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 403 | $6.70 |
| 2023-06-25 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 278 | $6.70 |
| 2023-06-16 | DUBOVSKY, FILIP | President, R&D | 普通株式 | 売却 | 2,007 | $8.04 |
| 2023-06-16 | DUBOVSKY, FILIP | President, R&D | 譲渡制限付株式ユニット | 売却 | 4,155 | $0.00 |
| 2023-06-16 | DUBOVSKY, FILIP | President, R&D | 普通株式 | 購入 | 4,155 | $8.04 |
| 2023-06-12 | DOUGLAS, RICHARD | Director | ストックオプション | 購入 | 7,710 | $0.00 |
| 2023-06-12 | ALTON, GREGG H | Director | 譲渡制限付株式ユニット | 購入 | 6,670 | $0.00 |
| 2023-06-12 | YOUNG, JAMES F | Director | ストックオプション | 購入 | 7,710 | $0.00 |
| 2023-06-12 | YOUNG, JAMES F | Director | 譲渡制限付株式ユニット | 購入 | 6,670 | $0.00 |
| 2023-06-12 | RODGERS, RICHARD J | Director | ストックオプション | 購入 | 7,710 | $0.00 |
| 2023-06-12 | RODGERS, RICHARD J | Director | 譲渡制限付株式ユニット | 購入 | 6,670 | $0.00 |
| 2023-06-12 | DOUGLAS, RICHARD | Director | 譲渡制限付株式ユニット | 購入 | 6,670 | $0.00 |
| 2023-06-12 | MOTT, DAVID M | Director | ストックオプション | 購入 | 7,710 | $0.00 |
| 2023-06-12 | MOTT, DAVID M | Director | 譲渡制限付株式ユニット | 購入 | 6,670 | $0.00 |
| 2023-06-12 | MCGLYNN, MARGARET G | Director | ストックオプション | 購入 | 7,710 | $0.00 |
| 2023-06-12 | MCGLYNN, MARGARET G | Director | 譲渡制限付株式ユニット | 購入 | 6,670 | $0.00 |
| 2023-06-12 | KING, RACHEL K. | Director | ストックオプション | 購入 | 7,710 | $0.00 |
| 2023-06-12 | KING, RACHEL K. | Director | 譲渡制限付株式ユニット | 購入 | 6,670 | $0.00 |
| 2023-06-12 | ALTON, GREGG H | Director | ストックオプション | 購入 | 7,710 | $0.00 |
| 2023-06-10 | ALTON, GREGG H | Director | 譲渡制限付株式ユニット | 売却 | 3,100 | $0.00 |
| 2023-06-10 | KING, RACHEL K. | Director | 譲渡制限付株式ユニット | 売却 | 3,100 | $0.00 |
| 2023-06-10 | YOUNG, JAMES F | Director | 普通株式 | 購入 | 4,600 | $ |
| 2023-06-10 | YOUNG, JAMES F | Director | 譲渡制限付株式ユニット | 売却 | 4,600 | $0.00 |
| 2023-06-10 | DOUGLAS, RICHARD | Director | 譲渡制限付株式ユニット | 売却 | 3,100 | $0.00 |
| 2023-06-10 | MCGLYNN, MARGARET G | Director | 普通株式 | 購入 | 3,100 | $ |
| 2023-06-10 | MCGLYNN, MARGARET G | Director | 譲渡制限付株式ユニット | 売却 | 3,100 | $0.00 |
| 2023-06-10 | ALTON, GREGG H | Director | 普通株式 | 購入 | 3,100 | $ |
| 2023-06-10 | DOUGLAS, RICHARD | Director | 普通株式 | 購入 | 3,100 | $ |
| 2023-06-10 | MOTT, DAVID M | Director | 普通株式 | 購入 | 3,100 | $ |
| 2023-06-10 | MOTT, DAVID M | Director | 譲渡制限付株式ユニット | 売却 | 3,100 | $0.00 |
| 2023-06-10 | KING, RACHEL K. | Director | 普通株式 | 購入 | 3,100 | $ |
| 2023-03-10 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 購入 | 4,609 | $6.52 |
| 2023-03-10 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 譲渡制限付株式ユニット | 売却 | 4,609 | $0.00 |
| 2023-03-10 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 1,000 | $6.50 |
| 2023-03-10 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 6,298 | $6.52 |
| 2023-03-10 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 2,432 | $6.52 |
| 2023-03-10 | GLENN, GREGORY M | President, R&D | 譲渡制限付株式ユニット | 売却 | 6,298 | $0.00 |
| 2023-03-10 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 2,471 | $6.52 |
| 2023-03-10 | TRIZZINO, JOHN | EVP, CCO and CBO | 譲渡制限付株式ユニット | 売却 | 4,609 | $0.00 |
| 2023-03-10 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 普通株式 | 購入 | 4,609 | $6.52 |
| 2023-03-10 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 普通株式 | 売却 | 2,471 | $6.52 |
| 2023-03-10 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 譲渡制限付株式ユニット | 売却 | 4,609 | $0.00 |
| 2023-03-10 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 4,609 | $6.52 |
| 2023-03-10 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 1,780 | $6.52 |
| 2023-03-07 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 購入 | 44,280 | $0.00 |
| 2023-03-07 | TRIZZINO, JOHN | EVP, CCO and CBO | ストックオプション | 購入 | 100,100 | $0.00 |
| 2023-03-07 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 譲渡制限付株式ユニット | 購入 | 38,330 | $0.00 |
| 2023-03-07 | TRIZZINO, JOHN | EVP, CCO and CBO | 譲渡制限付株式ユニット | 購入 | 86,670 | $0.00 |
| 2023-03-07 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 譲渡制限付株式ユニット | 購入 | 36,670 | $0.00 |
| 2023-03-07 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 2,000 | $7.04 |
| 2023-03-07 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | ストックオプション | 購入 | 42,350 | $0.00 |
| 2023-03-06 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 3,000 | $7.48 |
| 2023-03-01 | O'HARA, ELAINE | EVP, Chief Strategy Officer | 譲渡制限付株式ユニット | 購入 | 58,800 | $0.00 |
| 2023-03-01 | O'HARA, ELAINE | EVP, Chief Strategy Officer | ストックオプション | 購入 | 67,900 | $0.00 |
| 2023-01-23 | JACOBS, JOHN C | Director, President and CEO | 譲渡制限付株式ユニット | 購入 | 249,590 | $0.00 |
| 2023-01-23 | JACOBS, JOHN C | Director, President and CEO | ストックオプション | 購入 | 290,700 | $0.00 |
| 2022-12-14 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 購入 | 6,966 | $ |
| 2022-12-14 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 2,320 | $17.23 |
| 2022-12-14 | ERCK, STANLEY C | Director, President and CEO | 譲渡制限付株式ユニット | 売却 | 6,966 | $0.00 |
| 2022-12-14 | TRIZZINO, JOHN | EVP, CCO and CBO | 譲渡制限付株式ユニット | 売却 | 1,600 | $0.00 |
| 2022-12-14 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 773 | $17.23 |
| 2022-12-14 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 購入 | 1,600 | $ |
| 2022-12-14 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 2,100 | $ |
| 2022-12-14 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 700 | $17.23 |
| 2022-12-14 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 譲渡制限付株式ユニット | 売却 | 2,100 | $0.00 |
| 2022-12-14 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 3,100 | $ |
| 2022-12-14 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,033 | $17.23 |
| 2022-12-14 | GLENN, GREGORY M | President, R&D | 譲渡制限付株式ユニット | 売却 | 3,100 | $0.00 |
| 2022-10-29 | RODGERS, RICHARD J | Director | 譲渡制限付株式ユニット | 購入 | 11,400 | $0.00 |
| 2022-10-29 | RODGERS, RICHARD J | Director | ストックオプション | 購入 | 17,095 | $0.00 |
| 2022-09-26 | TRIZZINO, JOHN | EVP, CCO and CBO | 譲渡制限付株式ユニット | 売却 | 3,538 | $0.00 |
| 2022-09-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 譲渡制限付株式ユニット | 売却 | 667 | $0.00 |
| 2022-09-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 譲渡制限付株式ユニット | 売却 | 3,973 | $0.00 |
| 2022-09-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 258 | $18.87 |
| 2022-09-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 667 | $ |
| 2022-09-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 1,324 | $18.87 |
| 2022-09-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 3,973 | $ |
| 2022-09-26 | ERCK, STANLEY C | Director, President and CEO | 譲渡制限付株式ユニット | 売却 | 6,546 | $0.00 |
| 2022-09-26 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 2,180 | $18.87 |
| 2022-09-26 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 1,709 | $18.87 |
| 2022-09-26 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 購入 | 3,538 | $ |
| 2022-09-26 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 購入 | 6,546 | $ |
| 2022-08-24 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 2,000 | $ |
| 2022-08-24 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 772 | $37.07 |
| 2022-08-24 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 譲渡制限付株式ユニット | 売却 | 2,000 | $0.00 |
| 2022-08-19 | TRIZZINO, JOHN | EVP, CCO and CBO | 譲渡制限付株式ユニット | 売却 | 655 | $0.00 |
| 2022-08-19 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 購入 | 655 | $ |
| 2022-08-19 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 317 | $36.22 |
| 2022-08-16 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 譲渡制限付株式ユニット | 売却 | 2,367 | $0.00 |
| 2022-08-16 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 普通株式 | 売却 | 1,144 | $42.88 |
| 2022-08-16 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 普通株式 | 購入 | 2,367 | $ |
| 2022-06-25 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 譲渡制限付株式ユニット | 売却 | 833 | $0.00 |
| 2022-06-25 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 278 | $51.67 |
| 2022-06-25 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 278 | $51.67 |
| 2022-06-25 | TRIZZINO, JOHN | EVP, CCO and CBO | 譲渡制限付株式ユニット | 売却 | 833 | $0.00 |
| 2022-06-25 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 833 | $ |
| 2022-06-25 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 購入 | 833 | $ |
| 2022-06-17 | KING, RACHEL K. | Director | 譲渡制限付株式ユニット | 売却 | 700 | $0.00 |
| 2022-06-17 | YOUNG, JAMES F | Director | 普通株式 | 購入 | 1,400 | $ |
| 2022-06-17 | YOUNG, JAMES F | Director | 譲渡制限付株式ユニット | 売却 | 1,400 | $0.00 |
| 2022-06-17 | MOTT, DAVID M | Director | 普通株式 | 購入 | 700 | $ |
| 2022-06-17 | MOTT, DAVID M | Director | 譲渡制限付株式ユニット | 売却 | 700 | $0.00 |
| 2022-06-17 | MCGLYNN, MARGARET G | Director | 普通株式 | 購入 | 700 | $ |
| 2022-06-17 | MCGLYNN, MARGARET G | Director | 譲渡制限付株式ユニット | 売却 | 700 | $0.00 |
| 2022-06-17 | KING, RACHEL K. | Director | 普通株式 | 購入 | 700 | $ |
| 2022-06-17 | DOUGLAS, RICHARD | Director | 普通株式 | 購入 | 700 | $ |
| 2022-06-17 | DOUGLAS, RICHARD | Director | 譲渡制限付株式ユニット | 売却 | 700 | $0.00 |
| 2022-06-17 | ALTON, GREGG H | Director | 普通株式 | 購入 | 700 | $ |
| 2022-06-17 | ALTON, GREGG H | Director | 譲渡制限付株式ユニット | 売却 | 700 | $0.00 |
| 2022-06-16 | MCMANUS, MICHAEL A JR | Director | 普通株式 | 購入 | 700 | $ |
| 2022-06-16 | MCMANUS, MICHAEL A JR | Director | 譲渡制限付株式ユニット | 売却 | 700 | $0.00 |
| 2022-06-10 | MOTT, DAVID M | Director | 譲渡制限付株式ユニット | 購入 | 3,100 | $0.00 |
| 2022-06-10 | MOTT, DAVID M | Director | ストックオプション | 購入 | 4,600 | $0.00 |
| 2022-06-10 | YOUNG, JAMES F | Director | 譲渡制限付株式ユニット | 購入 | 4,600 | $0.00 |
| 2022-06-10 | YOUNG, JAMES F | Director | ストックオプション | 購入 | 6,900 | $0.00 |
| 2022-06-10 | ALTON, GREGG H | Director | 譲渡制限付株式ユニット | 購入 | 3,100 | $0.00 |
| 2022-06-10 | ALTON, GREGG H | Director | ストックオプション | 購入 | 4,600 | $0.00 |
| 2022-06-10 | DOUGLAS, RICHARD | Director | 譲渡制限付株式ユニット | 購入 | 3,100 | $0.00 |
| 2022-06-10 | DOUGLAS, RICHARD | Director | ストックオプション | 購入 | 4,600 | $0.00 |
| 2022-06-10 | KING, RACHEL K. | Director | 譲渡制限付株式ユニット | 購入 | 3,100 | $0.00 |
| 2022-06-10 | KING, RACHEL K. | Director | ストックオプション | 購入 | 4,600 | $0.00 |
| 2022-06-10 | MCGLYNN, MARGARET G | Director | 譲渡制限付株式ユニット | 購入 | 3,100 | $0.00 |
| 2022-06-10 | MCGLYNN, MARGARET G | Director | ストックオプション | 購入 | 4,600 | $0.00 |
| 2022-03-31 | YOUNG, JAMES F | Director | 普通株式 | 売却 | 300 | $75.10 |
| 2022-03-31 | YOUNG, JAMES F | Director | 普通株式 | 売却 | 3,255 | $74.25 |
| 2022-03-31 | YOUNG, JAMES F | Director | 普通株式 | 売却 | 8,945 | $73.29 |
| 2022-03-10 | GLENN, GREGORY M | President, R&D | ストックオプション | 購入 | 28,341 | $0.00 |
| 2022-03-10 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 譲渡制限付株式ユニット | 購入 | 13,825 | $0.00 |
| 2022-03-10 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 購入 | 20,737 | $0.00 |
| 2022-03-10 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 譲渡制限付株式ユニット | 購入 | 13,825 | $0.00 |
| 2022-03-10 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | ストックオプション | 購入 | 20,737 | $0.00 |
| 2022-03-10 | TRIZZINO, JOHN | EVP, CCO and CBO | 譲渡制限付株式ユニット | 購入 | 13,825 | $0.00 |
| 2022-03-10 | TRIZZINO, JOHN | EVP, CCO and CBO | ストックオプション | 購入 | 20,737 | $0.00 |
| 2022-03-10 | ERCK, STANLEY C | Director, President and CEO | 譲渡制限付株式ユニット | 購入 | 41,474 | $0.00 |
| 2022-03-10 | ERCK, STANLEY C | Director, President and CEO | ストックオプション | 購入 | 62,211 | $0.00 |
| 2022-03-10 | GLENN, GREGORY M | President, R&D | 譲渡制限付株式ユニット | 購入 | 18,894 | $0.00 |
| 2022-01-03 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2022-01-03 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 100 | $144.43 |
| 2022-01-03 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 1,003 | $143.64 |
| 2022-01-03 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 800 | $142.65 |
| 2022-01-03 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 800 | $141.69 |
| 2022-01-03 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 500 | $140.05 |
| 2022-01-03 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 997 | $139.08 |
| 2022-01-03 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 400 | $137.85 |
| 2022-01-03 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 400 | $136.82 |
| 2022-01-03 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 5,000 | $19.08 |
| 2021-12-31 | YOUNG, JAMES F | Director | ストックオプション | 売却 | 3,750 | $0.00 |
| 2021-12-31 | YOUNG, JAMES F | Director | 普通株式 | 購入 | 3,750 | $25.60 |
| 2021-12-31 | YOUNG, JAMES F | Director | 普通株式 | 売却 | 3,750 | $144.16 |
| 2021-12-20 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2021-12-20 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 5,000 | $19.08 |
| 2021-12-20 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 5,000 | $230.00 |
| 2021-12-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 67 | $175.89 |
| 2021-12-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 137 | $174.65 |
| 2021-12-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 91 | $173.29 |
| 2021-12-15 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 662 | $0.00 |
| 2021-12-15 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 1,024 | $0.00 |
| 2021-12-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 1,024 | $27.60 |
| 2021-12-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 248 | $172.38 |
| 2021-12-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 662 | $46.00 |
| 2021-12-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 117 | $168.82 |
| 2021-12-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 213 | $170.46 |
| 2021-12-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 254 | $171.47 |
| 2021-12-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 27 | $180.62 |
| 2021-12-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 206 | $179.58 |
| 2021-12-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 103 | $178.99 |
| 2021-12-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 223 | $176.83 |
| 2021-12-14 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 譲渡制限付株式ユニット | 売却 | 2,100 | $0.00 |
| 2021-12-14 | TRIZZINO, JOHN | EVP, CCO and CBO | 譲渡制限付株式ユニット | 売却 | 1,600 | $0.00 |
| 2021-12-14 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 3,100 | $ |
| 2021-12-14 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,498 | $168.43 |
| 2021-12-14 | ERCK, STANLEY C | Director, President and CEO | 譲渡制限付株式ユニット | 売却 | 6,967 | $0.00 |
| 2021-12-14 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 購入 | 6,967 | $ |
| 2021-12-14 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 3,366 | $168.43 |
| 2021-12-14 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 購入 | 1,600 | $ |
| 2021-12-14 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 773 | $168.43 |
| 2021-12-14 | GLENN, GREGORY M | President, R&D | 譲渡制限付株式ユニット | 売却 | 3,100 | $0.00 |
| 2021-12-14 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 2,100 | $ |
| 2021-12-14 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 1,015 | $168.43 |
| 2021-12-13 | DOUGLAS, RICHARD | Director | ストックオプション | 売却 | 1,500 | $0.00 |
| 2021-12-13 | DOUGLAS, RICHARD | Director | 普通株式 | 購入 | 1,500 | $25.60 |
| 2021-12-07 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 200 | $173.14 |
| 2021-12-07 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 200 | $171.30 |
| 2021-12-07 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 400 | $168.77 |
| 2021-12-07 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 300 | $167.06 |
| 2021-12-07 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 300 | $165.80 |
| 2021-12-07 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 300 | $164.77 |
| 2021-12-07 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 200 | $162.83 |
| 2021-12-07 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 300 | $161.63 |
| 2021-12-07 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 300 | $160.52 |
| 2021-12-07 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 300 | $158.42 |
| 2021-12-07 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 200 | $157.02 |
| 2021-12-07 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 300 | $156.24 |
| 2021-12-07 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 100 | $154.38 |
| 2021-12-07 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 397 | $153.53 |
| 2021-12-07 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 100 | $151.85 |
| 2021-12-07 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 200 | $150.30 |
| 2021-12-07 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 8,250 | $19.08 |
| 2021-12-07 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 500 | $178.21 |
| 2021-12-07 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 900 | $175.13 |
| 2021-12-07 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 8,250 | $0.00 |
| 2021-12-07 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 100 | $182.96 |
| 2021-12-07 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 853 | $182.30 |
| 2021-12-07 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 500 | $180.29 |
| 2021-12-07 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 500 | $179.36 |
| 2021-12-07 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 800 | $176.20 |
| 2021-12-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 900 | $194.54 |
| 2021-12-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 943 | $196.11 |
| 2021-12-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 300 | $197.19 |
| 2021-12-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 691 | $192.64 |
| 2021-12-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 5,000 | $19.08 |
| 2021-12-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 400 | $198.35 |
| 2021-12-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 800 | $193.79 |
| 2021-12-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 300 | $199.81 |
| 2021-12-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 300 | $200.92 |
| 2021-12-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 366 | $202.36 |
| 2021-12-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2021-11-30 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 100 | $211.75 |
| 2021-11-30 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 8,250 | $19.08 |
| 2021-11-30 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 121 | $189.98 |
| 2021-11-30 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 4 | $191.29 |
| 2021-11-30 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 222 | $192.58 |
| 2021-11-30 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 200 | $194.62 |
| 2021-11-30 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 518 | $195.87 |
| 2021-11-30 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 356 | $197.31 |
| 2021-11-30 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 836 | $198.17 |
| 2021-11-30 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 678 | $199.25 |
| 2021-11-30 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 717 | $200.40 |
| 2021-11-30 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 338 | $201.23 |
| 2021-11-30 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 715 | $202.37 |
| 2021-11-30 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 465 | $203.79 |
| 2021-11-30 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 439 | $206.06 |
| 2021-11-30 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 353 | $207.19 |
| 2021-11-30 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,450 | $208.78 |
| 2021-11-30 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 879 | $209.81 |
| 2021-11-30 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 551 | $210.57 |
| 2021-11-30 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 8,250 | $0.00 |
| 2021-11-29 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 5,000 | $228.72 |
| 2021-11-29 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 5,000 | $19.08 |
| 2021-11-29 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2021-11-26 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 2,083 | $0.00 |
| 2021-11-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,377 | $0.00 |
| 2021-11-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 412 | $219.25 |
| 2021-11-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 155 | $220.22 |
| 2021-11-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 114 | $221.24 |
| 2021-11-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 1,377 | $5.95 |
| 2021-11-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 2,083 | $5.95 |
| 2021-11-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 185 | $215.00 |
| 2021-11-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 331 | $217.36 |
| 2021-11-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 260 | $216.19 |
| 2021-11-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 38 | $217.97 |
| 2021-11-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 647 | $217.97 |
| 2021-11-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 626 | $218.25 |
| 2021-11-23 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,271 | $198.47 |
| 2021-11-23 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,387 | $199.51 |
| 2021-11-23 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,600 | $200.55 |
| 2021-11-23 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 870 | $202.65 |
| 2021-11-23 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 722 | $201.48 |
| 2021-11-23 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 8,250 | $0.00 |
| 2021-11-23 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 200 | $203.62 |
| 2021-11-23 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 800 | $196.43 |
| 2021-11-23 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,400 | $197.44 |
| 2021-11-23 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 8,250 | $19.08 |
| 2021-11-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 8,250 | $19.08 |
| 2021-11-16 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 8,250 | $0.00 |
| 2021-11-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 600 | $170.94 |
| 2021-11-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 4,352 | $170.26 |
| 2021-11-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,326 | $168.91 |
| 2021-11-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,472 | $167.95 |
| 2021-11-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 500 | $166.89 |
| 2021-11-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 521 | $27.60 |
| 2021-11-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,183 | $172.02 |
| 2021-11-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 662 | $46.00 |
| 2021-11-15 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 521 | $0.00 |
| 2021-11-15 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 662 | $0.00 |
| 2021-11-09 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,478 | $169.54 |
| 2021-11-09 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 100 | $171.48 |
| 2021-11-09 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 8,250 | $0.00 |
| 2021-11-09 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 2,000 | $167.76 |
| 2021-11-09 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 672 | $168.46 |
| 2021-11-09 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 400 | $170.55 |
| 2021-11-09 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 8,250 | $19.08 |
| 2021-11-09 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 400 | $164.23 |
| 2021-11-09 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,400 | $165.72 |
| 2021-11-09 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,800 | $166.55 |
| 2021-11-03 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2021-11-03 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 5,000 | $200.00 |
| 2021-11-03 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 5,000 | $19.08 |
| 2021-11-02 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 100 | $190.29 |
| 2021-11-02 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 100 | $197.51 |
| 2021-11-02 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 200 | $196.24 |
| 2021-11-02 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 378 | $195.54 |
| 2021-11-02 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 300 | $188.33 |
| 2021-11-02 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 500 | $186.09 |
| 2021-11-02 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 8,250 | $19.08 |
| 2021-11-02 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 600 | $177.12 |
| 2021-11-02 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,200 | $178.12 |
| 2021-11-02 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 900 | $179.09 |
| 2021-11-02 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 600 | $180.41 |
| 2021-11-02 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 670 | $181.55 |
| 2021-11-02 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 600 | $182.58 |
| 2021-11-02 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 800 | $183.58 |
| 2021-11-02 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 302 | $184.82 |
| 2021-11-02 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 300 | $187.26 |
| 2021-11-02 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 400 | $193.16 |
| 2021-11-02 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 300 | $194.40 |
| 2021-11-02 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 8,250 | $0.00 |
| 2021-11-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 5,000 | $19.08 |
| 2021-11-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 500 | $170.88 |
| 2021-11-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 200 | $169.05 |
| 2021-11-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 400 | $168.32 |
| 2021-11-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 200 | $167.15 |
| 2021-11-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 300 | $164.02 |
| 2021-11-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 400 | $155.16 |
| 2021-11-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 300 | $155.96 |
| 2021-11-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 800 | $157.42 |
| 2021-11-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 400 | $158.54 |
| 2021-11-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 343 | $159.90 |
| 2021-11-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 400 | $162.10 |
| 2021-11-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 100 | $162.69 |
| 2021-11-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 200 | $165.67 |
| 2021-11-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2021-11-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 157 | $173.15 |
| 2021-11-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 300 | $172.44 |
| 2021-10-29 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 138 | $148.08 |
| 2021-10-29 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 108 | $146.51 |
| 2021-10-29 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 16 | $149.64 |
| 2021-10-29 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 39 | $145.41 |
| 2021-10-29 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 353 | $148.99 |
| 2021-10-29 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 26 | $152.16 |
| 2021-10-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,378 | $0.00 |
| 2021-10-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 637 | $134.99 |
| 2021-10-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 2,084 | $5.95 |
| 2021-10-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 8,250 | $19.08 |
| 2021-10-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,500 | $130.93 |
| 2021-10-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 3,000 | $131.91 |
| 2021-10-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 3,134 | $133.02 |
| 2021-10-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,700 | $133.82 |
| 2021-10-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,000 | $135.16 |
| 2021-10-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 1,378 | $5.95 |
| 2021-10-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 61 | $134.99 |
| 2021-10-26 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 2,084 | $0.00 |
| 2021-10-26 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 8,250 | $0.00 |
| 2021-10-19 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,591 | $161.00 |
| 2021-10-19 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 300 | $169.85 |
| 2021-10-19 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 800 | $168.49 |
| 2021-10-19 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,400 | $164.85 |
| 2021-10-19 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 400 | $163.01 |
| 2021-10-19 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 893 | $162.05 |
| 2021-10-19 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 100 | $172.03 |
| 2021-10-19 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,366 | $167.08 |
| 2021-10-19 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,000 | $165.98 |
| 2021-10-19 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 8,250 | $19.08 |
| 2021-10-19 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 8,250 | $0.00 |
| 2021-10-19 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 400 | $171.02 |
| 2021-10-15 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 662 | $0.00 |
| 2021-10-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,183 | $170.00 |
| 2021-10-15 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 521 | $0.00 |
| 2021-10-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 662 | $46.00 |
| 2021-10-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 521 | $27.60 |
| 2021-10-12 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 8,250 | $0.00 |
| 2021-10-12 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,000 | $161.58 |
| 2021-10-12 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 2,900 | $162.45 |
| 2021-10-12 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 2,858 | $163.38 |
| 2021-10-12 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 800 | $164.50 |
| 2021-10-12 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 392 | $165.70 |
| 2021-10-12 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 300 | $166.78 |
| 2021-10-12 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 8,250 | $19.08 |
| 2021-10-05 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 8,250 | $19.08 |
| 2021-10-05 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 2,200 | $171.86 |
| 2021-10-05 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 700 | $172.70 |
| 2021-10-05 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 700 | $174.12 |
| 2021-10-05 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 600 | $175.32 |
| 2021-10-05 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 400 | $179.39 |
| 2021-10-05 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 8,250 | $0.00 |
| 2021-10-05 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 200 | $183.14 |
| 2021-10-05 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 400 | $180.41 |
| 2021-10-05 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 179 | $182.05 |
| 2021-10-05 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 600 | $178.37 |
| 2021-10-05 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 300 | $177.31 |
| 2021-10-05 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 500 | $176.49 |
| 2021-10-05 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,471 | $170.80 |
| 2021-10-04 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 3,300 | $179.48 |
| 2021-10-04 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 3,600 | $175.61 |
| 2021-10-04 | ERCK, STANLEY C | Director, President and CEO | ストックオプション | 売却 | 10,829 | $0.00 |
| 2021-10-04 | ERCK, STANLEY C | Director, President and CEO | ストックオプション | 売却 | 32,000 | $0.00 |
| 2021-10-04 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 4,700 | $176.48 |
| 2021-10-04 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 8,890 | $177.58 |
| 2021-10-04 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 8,563 | $178.46 |
| 2021-10-04 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 購入 | 32,000 | $27.60 |
| 2021-10-04 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 購入 | 10,829 | $27.00 |
| 2021-10-04 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 1,392 | $166.98 |
| 2021-10-04 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 3,746 | $172.36 |
| 2021-10-04 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 5,038 | $173.45 |
| 2021-10-04 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 3,100 | $174.56 |
| 2021-10-04 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 500 | $180.58 |
| 2021-10-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 200 | $169.17 |
| 2021-10-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 200 | $172.46 |
| 2021-10-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 400 | $173.83 |
| 2021-10-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 400 | $174.74 |
| 2021-10-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 500 | $175.91 |
| 2021-10-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 500 | $177.02 |
| 2021-10-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 600 | $178.00 |
| 2021-10-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 352 | $179.27 |
| 2021-10-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 5,853 | $174.30 |
| 2021-10-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 3,602 | $175.15 |
| 2021-10-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 2,601 | $176.24 |
| 2021-10-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 6,227 | $177.37 |
| 2021-10-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 4,604 | $178.27 |
| 2021-10-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 1,323 | $179.29 |
| 2021-10-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 2,541 | $180.42 |
| 2021-10-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 1,600 | $181.21 |
| 2021-10-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 300 | $182.40 |
| 2021-10-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 192 | $183.61 |
| 2021-10-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 購入 | 14,000 | $27.60 |
| 2021-10-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 100 | $181.36 |
| 2021-10-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 300 | $189.68 |
| 2021-10-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 48 | $190.63 |
| 2021-10-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2021-10-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 購入 | 35,000 | $27.00 |
| 2021-10-01 | ERCK, STANLEY C | Director, President and CEO | ストックオプション | 売却 | 14,000 | $0.00 |
| 2021-10-01 | ERCK, STANLEY C | Director, President and CEO | ストックオプション | 売却 | 35,000 | $0.00 |
| 2021-10-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 5,000 | $19.08 |
| 2021-10-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 400 | $165.40 |
| 2021-10-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 100 | $166.19 |
| 2021-10-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 300 | $168.03 |
| 2021-10-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 600 | $171.60 |
| 2021-10-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 472 | $190.63 |
| 2021-10-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 1,502 | $189.47 |
| 2021-10-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 100 | $187.95 |
| 2021-10-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 8 | $185.71 |
| 2021-10-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 3,002 | $173.16 |
| 2021-10-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 4,103 | $172.02 |
| 2021-10-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 2,602 | $171.34 |
| 2021-10-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 901 | $170.07 |
| 2021-10-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 1,959 | $169.05 |
| 2021-10-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 2,801 | $167.88 |
| 2021-10-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 1,100 | $166.62 |
| 2021-10-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 904 | $165.68 |
| 2021-10-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 703 | $164.74 |
| 2021-09-30 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 40 | $210.16 |
| 2021-09-30 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 16 | $211.39 |
| 2021-09-30 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 118 | $209.27 |
| 2021-09-30 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 117 | $207.99 |
| 2021-09-30 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 280 | $207.01 |
| 2021-09-30 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 16 | $205.01 |
| 2021-09-30 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 55 | $203.94 |
| 2021-09-30 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 51 | $202.84 |
| 2021-09-28 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 30 | $213.11 |
| 2021-09-28 | TRIZZINO, JOHN | EVP, CCO and CBO | ストックオプション | 売却 | 7,501 | $0.00 |
| 2021-09-28 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 1,452 | $205.25 |
| 2021-09-28 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 990 | $206.30 |
| 2021-09-28 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 156 | $230.00 |
| 2021-09-28 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 購入 | 7,501 | $19.08 |
| 2021-09-28 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 839 | $203.26 |
| 2021-09-28 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 1,141 | $204.12 |
| 2021-09-28 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 382 | $207.32 |
| 2021-09-28 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 312 | $208.46 |
| 2021-09-28 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 112 | $209.57 |
| 2021-09-28 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 100 | $211.45 |
| 2021-09-28 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 318 | $214.65 |
| 2021-09-28 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 247 | $216.21 |
| 2021-09-28 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 226 | $218.13 |
| 2021-09-28 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 421 | $219.26 |
| 2021-09-28 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 49 | $220.22 |
| 2021-09-28 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 255 | $222.86 |
| 2021-09-28 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 148 | $224.24 |
| 2021-09-28 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 323 | $228.25 |
| 2021-09-27 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 114 | $240.60 |
| 2021-09-27 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 369 | $235.77 |
| 2021-09-27 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 314 | $228.69 |
| 2021-09-27 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 849 | $234.37 |
| 2021-09-27 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 53 | $243.20 |
| 2021-09-27 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 100 | $237.58 |
| 2021-09-27 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 2,083 | $5.95 |
| 2021-09-27 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 57 | $228.12 |
| 2021-09-27 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 225 | $229.99 |
| 2021-09-27 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 272 | $231.07 |
| 2021-09-27 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 318 | $232.00 |
| 2021-09-27 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 262 | $233.24 |
| 2021-09-27 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 217 | $233.87 |
| 2021-09-27 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 203 | $235.10 |
| 2021-09-27 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 98 | $236.30 |
| 2021-09-27 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 57 | $237.29 |
| 2021-09-27 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 124 | $239.04 |
| 2021-09-27 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 99 | $240.37 |
| 2021-09-27 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 56 | $243.98 |
| 2021-09-27 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 95 | $248.13 |
| 2021-09-27 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 1,377 | $5.95 |
| 2021-09-27 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 36 | $231.04 |
| 2021-09-27 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 648 | $231.04 |
| 2021-09-27 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 2,083 | $0.00 |
| 2021-09-27 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,377 | $0.00 |
| 2021-09-27 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 100 | $246.49 |
| 2021-09-27 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 212 | $244.99 |
| 2021-09-27 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 569 | $239.71 |
| 2021-09-27 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 購入 | 7,501 | $19.08 |
| 2021-09-27 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 297 | $248.16 |
| 2021-09-27 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 70 | $249.04 |
| 2021-09-27 | TRIZZINO, JOHN | EVP, CCO and CBO | ストックオプション | 売却 | 7,501 | $0.00 |
| 2021-09-27 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 1,270 | $233.25 |
| 2021-09-27 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 924 | $231.95 |
| 2021-09-27 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 1,365 | $231.16 |
| 2021-09-27 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 628 | $230.19 |
| 2021-09-27 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 267 | $236.75 |
| 2021-09-26 | TRIZZINO, JOHN | EVP, CCO and CBO | 譲渡制限付株式ユニット | 売却 | 3,537 | $0.00 |
| 2021-09-26 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 1,709 | $248.16 |
| 2021-09-26 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 購入 | 3,537 | $ |
| 2021-09-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 3,973 | $ |
| 2021-09-26 | ERCK, STANLEY C | Director, President and CEO | 譲渡制限付株式ユニット | 売却 | 6,546 | $0.00 |
| 2021-09-26 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 3,162 | $248.16 |
| 2021-09-26 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 購入 | 6,546 | $ |
| 2021-09-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 譲渡制限付株式ユニット | 売却 | 666 | $0.00 |
| 2021-09-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 譲渡制限付株式ユニット | 売却 | 3,973 | $0.00 |
| 2021-09-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 222 | $248.16 |
| 2021-09-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 666 | $ |
| 2021-09-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 1,919 | $248.16 |
| 2021-09-23 | MOTT, DAVID M | Director | 普通株式 | 売却 | 7,557 | $252.56 |
| 2021-09-23 | MOTT, DAVID M | Director | 普通株式 | 売却 | 5,728 | $251.32 |
| 2021-09-23 | MOTT, DAVID M | Director | 普通株式 | 売却 | 1,200 | $255.38 |
| 2021-09-23 | MOTT, DAVID M | Director | 普通株式 | 売却 | 2,732 | $254.46 |
| 2021-09-23 | MOTT, DAVID M | Director | 普通株式 | 売却 | 7,744 | $253.46 |
| 2021-09-21 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 853 | $228.22 |
| 2021-09-21 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 585 | $227.09 |
| 2021-09-21 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 1,365 | $226.24 |
| 2021-09-21 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 購入 | 7,500 | $19.08 |
| 2021-09-21 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 819 | $223.95 |
| 2021-09-21 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 1,269 | $224.79 |
| 2021-09-21 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 368 | $231.11 |
| 2021-09-21 | TRIZZINO, JOHN | EVP, CCO and CBO | ストックオプション | 売却 | 7,500 | $0.00 |
| 2021-09-21 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 1,515 | $230.31 |
| 2021-09-21 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 726 | $229.03 |
| 2021-09-20 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 112 | $232.90 |
| 2021-09-20 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 購入 | 7,500 | $19.08 |
| 2021-09-20 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 662 | $223.18 |
| 2021-09-20 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 705 | $224.77 |
| 2021-09-20 | TRIZZINO, JOHN | EVP, CCO and CBO | ストックオプション | 売却 | 7,500 | $0.00 |
| 2021-09-20 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 1,032 | $225.68 |
| 2021-09-20 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 1,175 | $226.65 |
| 2021-09-20 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 578 | $227.87 |
| 2021-09-20 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 1,307 | $228.72 |
| 2021-09-20 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 918 | $229.92 |
| 2021-09-20 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 755 | $230.69 |
| 2021-09-20 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 256 | $231.90 |
| 2021-09-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 204 | $226.66 |
| 2021-09-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 196 | $231.08 |
| 2021-09-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 99 | $227.89 |
| 2021-09-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 96 | $228.93 |
| 2021-09-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 165 | $232.01 |
| 2021-09-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 65 | $233.02 |
| 2021-09-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 45 | $234.73 |
| 2021-09-15 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 521 | $0.00 |
| 2021-09-15 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 662 | $0.00 |
| 2021-09-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 521 | $27.60 |
| 2021-09-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 662 | $46.00 |
| 2021-09-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 62 | $224.59 |
| 2021-09-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 99 | $225.70 |
| 2021-09-15 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2021-09-15 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 262 | $234.90 |
| 2021-09-15 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 300 | $232.57 |
| 2021-09-15 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 1,112 | $231.91 |
| 2021-09-15 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 500 | $230.52 |
| 2021-09-15 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 800 | $229.57 |
| 2021-09-15 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 300 | $228.22 |
| 2021-09-15 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 520 | $227.34 |
| 2021-09-15 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 906 | $226.34 |
| 2021-09-15 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 200 | $224.94 |
| 2021-09-15 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 100 | $223.51 |
| 2021-09-15 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 5,000 | $19.08 |
| 2021-09-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 152 | $230.10 |
| 2021-09-14 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 1,423 | $238.10 |
| 2021-09-14 | TRIZZINO, JOHN | EVP, CCO and CBO | ストックオプション | 売却 | 7,499 | $0.00 |
| 2021-09-14 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 購入 | 7,499 | $19.08 |
| 2021-09-14 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 898 | $233.17 |
| 2021-09-14 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 905 | $233.90 |
| 2021-09-14 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 682 | $235.16 |
| 2021-09-14 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 1,422 | $236.16 |
| 2021-09-14 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 799 | $237.14 |
| 2021-09-14 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 564 | $238.95 |
| 2021-09-14 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 590 | $240.37 |
| 2021-09-14 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 216 | $241.70 |
| 2021-09-13 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 1,317 | $232.24 |
| 2021-09-13 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 1,279 | $233.25 |
| 2021-09-13 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 購入 | 7,499 | $19.08 |
| 2021-09-13 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 429 | $231.29 |
| 2021-09-13 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 74 | $242.62 |
| 2021-09-13 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 333 | $245.16 |
| 2021-09-13 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 244 | $247.33 |
| 2021-09-13 | TRIZZINO, JOHN | EVP, CCO and CBO | ストックオプション | 売却 | 7,499 | $0.00 |
| 2021-09-13 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 66 | $238.13 |
| 2021-09-13 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 493 | $237.84 |
| 2021-09-13 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 880 | $236.38 |
| 2021-09-13 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 1,293 | $235.50 |
| 2021-09-13 | TRIZZINO, JOHN | EVP, CCO and CBO | 普通株式 | 売却 | 1,091 | $234.26 |
| 2021-09-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 5,000 | $19.08 |
| 2021-09-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 256 | $238.81 |
| 2021-09-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 300 | $240.51 |
| 2021-09-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 500 | $242.97 |
| 2021-09-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 100 | $237.23 |
| 2021-09-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 100 | $235.85 |
| 2021-09-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 100 | $241.39 |
| 2021-09-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 400 | $244.33 |
| 2021-09-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 500 | $245.82 |
| 2021-09-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 300 | $246.80 |
| 2021-09-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 100 | $248.33 |
| 2021-09-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 344 | $250.00 |
| 2021-09-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 400 | $251.68 |
| 2021-09-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 600 | $253.20 |
| 2021-09-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 400 | $254.83 |
| 2021-09-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 600 | $256.01 |
| 2021-09-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2021-08-31 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 100 | $242.63 |
| 2021-08-31 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 209 | $241.59 |
| 2021-08-31 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 175 | $240.58 |
| 2021-08-31 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 359 | $239.66 |
| 2021-08-31 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 320 | $238.72 |
| 2021-08-31 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 108 | $237.14 |
| 2021-08-31 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 53 | $234.64 |
| 2021-08-31 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 62 | $244.03 |
| 2021-08-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 2,754 | $5.95 |
| 2021-08-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 100 | $240.04 |
| 2021-08-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 616 | $233.89 |
| 2021-08-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 700 | $232.89 |
| 2021-08-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 400 | $231.35 |
| 2021-08-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 605 | $230.52 |
| 2021-08-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 200 | $229.35 |
| 2021-08-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 100 | $227.74 |
| 2021-08-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 4,167 | $5.95 |
| 2021-08-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,296 | $230.34 |
| 2021-08-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 72 | $230.34 |
| 2021-08-26 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 4,167 | $0.00 |
| 2021-08-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 2,754 | $0.00 |
| 2021-08-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 346 | $238.62 |
| 2021-08-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 400 | $237.35 |
| 2021-08-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 200 | $236.13 |
| 2021-08-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 400 | $235.27 |
| 2021-08-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 100 | $241.57 |
| 2021-08-24 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 697 | $233.01 |
| 2021-08-24 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 2,000 | $ |
| 2021-08-24 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 譲渡制限付株式ユニット | 売却 | 2,000 | $0.00 |
| 2021-08-19 | TRIZZINO, JOHN | EVP, CCO and CBO | 譲渡制限付株式ユニット | 購入 | 1,965 | $0.00 |
| 2021-08-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 61 | $239.32 |
| 2021-08-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 63 | $237.92 |
| 2021-08-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 48 | $236.22 |
| 2021-08-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 13 | $234.88 |
| 2021-08-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 177 | $234.38 |
| 2021-08-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 153 | $233.17 |
| 2021-08-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 274 | $232.15 |
| 2021-08-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 204 | $231.27 |
| 2021-08-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 219 | $230.00 |
| 2021-08-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 78 | $240.37 |
| 2021-08-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 141 | $227.79 |
| 2021-08-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 57 | $225.98 |
| 2021-08-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 55 | $223.26 |
| 2021-08-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 1,322 | $46.00 |
| 2021-08-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 544 | $27.60 |
| 2021-08-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 107 | $242.99 |
| 2021-08-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 50 | $244.99 |
| 2021-08-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 51 | $246.72 |
| 2021-08-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 14 | $248.98 |
| 2021-08-16 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 544 | $0.00 |
| 2021-08-16 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 1,322 | $0.00 |
| 2021-08-16 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | 譲渡制限付株式ユニット | 購入 | 7,100 | $0.00 |
| 2021-08-16 | KELLY, JAMES PATRICK | EVP, CFO and Treasurer | ストックオプション | 購入 | 14,200 | $0.00 |
| 2021-08-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 101 | $228.79 |
| 2021-07-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 417 | $46.00 |
| 2021-07-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 2,062 | $5.95 |
| 2021-07-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 151 | $193.09 |
| 2021-07-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 423 | $194.26 |
| 2021-07-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 263 | $195.29 |
| 2021-07-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 313 | $196.12 |
| 2021-07-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 485 | $197.47 |
| 2021-07-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 317 | $198.20 |
| 2021-07-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 224 | $199.47 |
| 2021-07-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 256 | $200.47 |
| 2021-07-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 129 | $202.58 |
| 2021-07-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 417 | $27.60 |
| 2021-07-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 209 | $201.56 |
| 2021-07-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 58 | $203.45 |
| 2021-07-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 68 | $204.57 |
| 2021-07-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 売却 | 417 | $0.00 |
| 2021-07-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 売却 | 2,062 | $0.00 |
| 2021-07-20 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 119 | $200.61 |
| 2021-07-20 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 63 | $224.33 |
| 2021-07-20 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 173 | $225.91 |
| 2021-07-20 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 306 | $227.17 |
| 2021-07-20 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 189 | $228.60 |
| 2021-07-20 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 56 | $229.44 |
| 2021-07-20 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 240 | $220.66 |
| 2021-07-20 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 56 | $218.69 |
| 2021-07-20 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 56 | $217.44 |
| 2021-07-20 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 126 | $214.76 |
| 2021-07-20 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 141 | $213.55 |
| 2021-07-20 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 63 | $211.93 |
| 2021-07-20 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 126 | $207.63 |
| 2021-07-20 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 135 | $206.82 |
| 2021-07-20 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 181 | $205.66 |
| 2021-07-20 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 119 | $204.71 |
| 2021-07-20 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 61 | $203.39 |
| 2021-07-20 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 199 | $202.76 |
| 2021-07-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 550 | $27.00 |
| 2021-07-15 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 870 | $0.00 |
| 2021-07-15 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 550 | $0.00 |
| 2021-07-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 2,253 | $179.14 |
| 2021-07-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 161 | $179.14 |
| 2021-07-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 4,823 | $5.95 |
| 2021-07-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1 | $184.27 |
| 2021-07-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 399 | $183.81 |
| 2021-07-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 300 | $182.38 |
| 2021-07-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 4,823 | $0.00 |
| 2021-07-15 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 1,105 | $0.00 |
| 2021-07-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 560 | $181.45 |
| 2021-07-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 550 | $180.57 |
| 2021-07-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 796 | $179.29 |
| 2021-07-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 2,318 | $178.19 |
| 2021-07-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 730 | $177.62 |
| 2021-07-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 3,129 | $5.95 |
| 2021-07-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 1,105 | $46.00 |
| 2021-07-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 870 | $27.60 |
| 2021-07-15 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 3,129 | $0.00 |
| 2021-07-02 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 4,466 | $214.76 |
| 2021-07-02 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 2,355 | $213.38 |
| 2021-07-02 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 7,616 | $212.29 |
| 2021-07-02 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 4,242 | $211.21 |
| 2021-07-02 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 1,970 | $210.23 |
| 2021-07-02 | ERCK, STANLEY C | Director, President and CEO | ストックオプション | 売却 | 25,120 | $0.00 |
| 2021-07-02 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 購入 | 25,120 | $36.60 |
| 2021-07-02 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 購入 | 27,439 | $121.00 |
| 2021-07-02 | ERCK, STANLEY C | Director, President and CEO | ストックオプション | 売却 | 27,439 | $0.00 |
| 2021-07-02 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 675 | $221.53 |
| 2021-07-02 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 628 | $220.80 |
| 2021-07-02 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 5,031 | $219.76 |
| 2021-07-02 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 7,423 | $218.77 |
| 2021-07-02 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 9,969 | $217.84 |
| 2021-07-02 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 2,994 | $216.92 |
| 2021-07-02 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 5,190 | $215.74 |
| 2021-07-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 12,917 | $214.13 |
| 2021-07-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 1,329 | $215.70 |
| 2021-07-01 | ERCK, STANLEY C | Director, President and CEO | ストックオプション | 売却 | 17,560 | $0.00 |
| 2021-07-01 | ERCK, STANLEY C | Director, President and CEO | ストックオプション | 売却 | 19,879 | $0.00 |
| 2021-07-01 | ERCK, STANLEY C | Director, President and CEO | ストックオプション | 売却 | 15,181 | $0.00 |
| 2021-07-01 | YOUNG, JAMES F | Director | 普通株式 | 購入 | 10,000 | $ |
| 2021-07-01 | YOUNG, JAMES F | Director | 譲渡制限付株式ユニット | 売却 | 10,000 | $0.00 |
| 2021-07-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 購入 | 15,181 | $25.60 |
| 2021-07-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 購入 | 19,879 | $36.60 |
| 2021-07-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 購入 | 17,560 | $121.00 |
| 2021-07-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 2,046 | $209.20 |
| 2021-07-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 6,105 | $210.02 |
| 2021-07-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 4,117 | $211.07 |
| 2021-07-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 6,419 | $212.15 |
| 2021-07-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 12,703 | $213.07 |
| 2021-07-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 6,984 | $214.97 |
| 2021-06-30 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 360 | $214.23 |
| 2021-06-30 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 299 | $215.16 |
| 2021-06-30 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 購入 | 416 | $0.00 |
| 2021-06-30 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 購入 | 417 | $0.00 |
| 2021-06-30 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 購入 | 2,063 | $0.00 |
| 2021-06-30 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 11 | $216.85 |
| 2021-06-30 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 192 | $216.11 |
| 2021-06-30 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 313 | $212.98 |
| 2021-06-30 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 1,126 | $212.14 |
| 2021-06-30 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 171 | $211.22 |
| 2021-06-30 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 309 | $209.89 |
| 2021-06-30 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 417 | $46.00 |
| 2021-06-30 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 416 | $27.60 |
| 2021-06-30 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 2,063 | $5.95 |
| 2021-06-30 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 115 | $208.75 |
| 2021-06-25 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 834 | $ |
| 2021-06-25 | TRIZZINO, JOHN | EVP, CCO, CBO & Interim CFO | 普通株式 | 売却 | 403 | $189.79 |
| 2021-06-25 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 譲渡制限付株式ユニット | 売却 | 834 | $0.00 |
| 2021-06-25 | MCMANUS, MICHAEL A JR | Director | 普通株式 | 購入 | 6,900 | $ |
| 2021-06-25 | MCMANUS, MICHAEL A JR | Director | 譲渡制限付株式ユニット | 売却 | 6,900 | $0.00 |
| 2021-06-25 | KING, RACHEL K. | Director | 普通株式 | 購入 | 6,900 | $ |
| 2021-06-25 | KING, RACHEL K. | Director | 譲渡制限付株式ユニット | 売却 | 6,900 | $0.00 |
| 2021-06-25 | DOUGLAS, RICHARD | Director | 普通株式 | 購入 | 3,450 | $ |
| 2021-06-25 | DOUGLAS, RICHARD | Director | 譲渡制限付株式ユニット | 売却 | 3,450 | $0.00 |
| 2021-06-25 | YOUNG, JAMES F | Director | 普通株式 | 購入 | 7,590 | $ |
| 2021-06-25 | YOUNG, JAMES F | Director | 譲渡制限付株式ユニット | 売却 | 7,590 | $0.00 |
| 2021-06-25 | TRIZZINO, JOHN | EVP, CCO, CBO & Interim CFO | 普通株式 | 購入 | 834 | $ |
| 2021-06-25 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 403 | $189.79 |
| 2021-06-25 | MCMANUS, MICHAEL A JR | Director | 普通株式 | 購入 | 3,450 | $ |
| 2021-06-25 | MCMANUS, MICHAEL A JR | Director | 譲渡制限付株式ユニット | 売却 | 3,450 | $0.00 |
| 2021-06-25 | KING, RACHEL K. | Director | 普通株式 | 購入 | 3,450 | $ |
| 2021-06-25 | KING, RACHEL K. | Director | 譲渡制限付株式ユニット | 売却 | 3,450 | $0.00 |
| 2021-06-25 | TRIZZINO, JOHN | EVP, CCO, CBO & Interim CFO | 譲渡制限付株式ユニット | 売却 | 834 | $0.00 |
| 2021-06-17 | DOUGLAS, RICHARD | Director | 譲渡制限付株式ユニット | 購入 | 700 | $0.00 |
| 2021-06-17 | ALTON, GREGG H | Director | 譲渡制限付株式ユニット | 購入 | 700 | $0.00 |
| 2021-06-17 | YOUNG, JAMES F | Director | ストックオプション | 購入 | 2,600 | $0.00 |
| 2021-06-17 | YOUNG, JAMES F | Director | 譲渡制限付株式ユニット | 購入 | 1,400 | $0.00 |
| 2021-06-17 | EVANS, GARY C | Director | 普通株式 | 購入 | 3,450 | $ |
| 2021-06-17 | MCMANUS, MICHAEL A JR | Director | ストックオプション | 購入 | 1,300 | $0.00 |
| 2021-06-17 | MOTT, DAVID M | Director | 譲渡制限付株式ユニット | 購入 | 700 | $0.00 |
| 2021-06-17 | EVANS, GARY C | Director | 譲渡制限付株式ユニット | 売却 | 3,450 | $0.00 |
| 2021-06-17 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 2,411 | $183.28 |
| 2021-06-17 | MOTT, DAVID M | Director | ストックオプション | 購入 | 1,300 | $0.00 |
| 2021-06-17 | MCMANUS, MICHAEL A JR | Director | 譲渡制限付株式ユニット | 購入 | 700 | $0.00 |
| 2021-06-17 | MCGLYNN, MARGARET G | Director | ストックオプション | 購入 | 1,300 | $0.00 |
| 2021-06-17 | MCGLYNN, MARGARET G | Director | 譲渡制限付株式ユニット | 購入 | 700 | $0.00 |
| 2021-06-17 | KING, RACHEL K. | Director | ストックオプション | 購入 | 1,300 | $0.00 |
| 2021-06-17 | KING, RACHEL K. | Director | 譲渡制限付株式ユニット | 購入 | 700 | $0.00 |
| 2021-06-17 | DOUGLAS, RICHARD | Director | ストックオプション | 購入 | 1,300 | $0.00 |
| 2021-06-17 | ALTON, GREGG H | Director | ストックオプション | 購入 | 1,300 | $0.00 |
| 2021-06-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 200 | $198.39 |
| 2021-06-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 4,819 | $0.00 |
| 2021-06-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 448 | $200.00 |
| 2021-06-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 2,254 | $187.07 |
| 2021-06-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 188 | $195.24 |
| 2021-06-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 4,819 | $5.95 |
| 2021-06-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 335 | $194.35 |
| 2021-06-15 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 1,101 | $0.00 |
| 2021-06-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 623 | $27.00 |
| 2021-06-15 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 3,124 | $0.00 |
| 2021-06-15 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 623 | $0.00 |
| 2021-06-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 154 | $187.07 |
| 2021-06-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 310 | $196.65 |
| 2021-06-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 557 | $193.50 |
| 2021-06-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 121 | $192.14 |
| 2021-06-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 261 | $191.25 |
| 2021-06-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,387 | $190.31 |
| 2021-06-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 53 | $189.62 |
| 2021-06-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 8 | $187.86 |
| 2021-06-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,810 | $187.04 |
| 2021-06-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 37 | $186.45 |
| 2021-06-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1 | $183.53 |
| 2021-06-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 3,124 | $5.95 |
| 2021-06-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 1,101 | $46.00 |
| 2021-06-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 868 | $27.60 |
| 2021-06-15 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 868 | $0.00 |
| 2021-06-01 | EVANS, GARY C | Director | 普通株式 | 売却 | 625 | $146.50 |
| 2021-05-28 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 70 | $153.49 |
| 2021-05-28 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 416 | $27.60 |
| 2021-05-28 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 417 | $46.00 |
| 2021-05-28 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 2,062 | $5.95 |
| 2021-05-28 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 864 | $147.85 |
| 2021-05-28 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 1,109 | $148.88 |
| 2021-05-28 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 517 | $149.81 |
| 2021-05-28 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 240 | $151.08 |
| 2021-05-28 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 95 | $152.11 |
| 2021-05-28 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 購入 | 416 | $0.00 |
| 2021-05-28 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 購入 | 417 | $0.00 |
| 2021-05-28 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 購入 | 2,062 | $0.00 |
| 2021-05-19 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 170 | $145.83 |
| 2021-05-19 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 62 | $138.29 |
| 2021-05-19 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 89 | $140.04 |
| 2021-05-19 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 586 | $142.12 |
| 2021-05-19 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,018 | $141.23 |
| 2021-05-19 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 162 | $144.36 |
| 2021-05-19 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 298 | $143.62 |
| 2021-05-19 | KING, RACHEL K. | Director | 普通株式 | 購入 | 700 | $139.64 |
| 2021-05-17 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 2,229 | $140.16 |
| 2021-05-17 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 205 | $140.16 |
| 2021-05-17 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 4,819 | $5.95 |
| 2021-05-17 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 3,124 | $5.95 |
| 2021-05-17 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,348 | $133.10 |
| 2021-05-17 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 3,364 | $135.06 |
| 2021-05-17 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 4,819 | $0.00 |
| 2021-05-17 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 3,124 | $0.00 |
| 2021-05-17 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 1,101 | $0.00 |
| 2021-05-17 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 868 | $0.00 |
| 2021-05-17 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 619 | $0.00 |
| 2021-05-17 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 1,101 | $46.00 |
| 2021-05-17 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,000 | $131.50 |
| 2021-05-17 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 619 | $27.00 |
| 2021-05-17 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 868 | $27.60 |
| 2021-05-07 | TRIZZINO, JOHN | EVP, CCO, CBO & Interim CFO | 普通株式 | 売却 | 90 | $176.60 |
| 2021-05-07 | TRIZZINO, JOHN | EVP, CCO, CBO & Interim CFO | 普通株式 | 売却 | 100 | $176.65 |
| 2021-05-05 | TRIZZINO, JOHN | EVP, CCO, CBO & Interim CFO | 普通株式 | 売却 | 246 | $192.81 |
| 2021-05-05 | TRIZZINO, JOHN | EVP, CCO, CBO & Interim CFO | 普通株式 | 売却 | 384 | $0.00 |
| 2021-05-05 | TRIZZINO, JOHN | EVP, CCO, CBO & Interim CFO | ストックオプション | 売却 | 2,084 | $0.00 |
| 2021-05-05 | TRIZZINO, JOHN | EVP, CCO, CBO & Interim CFO | 普通株式 | 売却 | 93 | $169.70 |
| 2021-05-05 | TRIZZINO, JOHN | EVP, CCO, CBO & Interim CFO | 普通株式 | 売却 | 208 | $171.09 |
| 2021-05-05 | TRIZZINO, JOHN | EVP, CCO, CBO & Interim CFO | 普通株式 | 売却 | 28 | $171.89 |
| 2021-05-05 | TRIZZINO, JOHN | EVP, CCO, CBO & Interim CFO | 普通株式 | 売却 | 70 | $180.37 |
| 2021-05-05 | TRIZZINO, JOHN | EVP, CCO, CBO & Interim CFO | 普通株式 | 売却 | 85 | $181.17 |
| 2021-05-05 | TRIZZINO, JOHN | EVP, CCO, CBO & Interim CFO | 普通株式 | 売却 | 160 | $182.45 |
| 2021-05-05 | TRIZZINO, JOHN | EVP, CCO, CBO & Interim CFO | 普通株式 | 売却 | 138 | $183.43 |
| 2021-05-05 | TRIZZINO, JOHN | EVP, CCO, CBO & Interim CFO | 普通株式 | 売却 | 252 | $184.25 |
| 2021-05-05 | TRIZZINO, JOHN | EVP, CCO, CBO & Interim CFO | ストックオプション | 売却 | 521 | $0.00 |
| 2021-05-05 | TRIZZINO, JOHN | EVP, CCO, CBO & Interim CFO | ストックオプション | 売却 | 417 | $0.00 |
| 2021-05-05 | TRIZZINO, JOHN | EVP, CCO, CBO & Interim CFO | 普通株式 | 売却 | 180 | $171.74 |
| 2021-05-05 | TRIZZINO, JOHN | EVP, CCO, CBO & Interim CFO | 普通株式 | 売却 | 14 | $171.74 |
| 2021-05-05 | TRIZZINO, JOHN | EVP, CCO, CBO & Interim CFO | 普通株式 | 購入 | 384 | $5.95 |
| 2021-05-05 | TRIZZINO, JOHN | EVP, CCO, CBO & Interim CFO | 普通株式 | 売却 | 364 | $189.46 |
| 2021-05-05 | TRIZZINO, JOHN | EVP, CCO, CBO & Interim CFO | 普通株式 | 売却 | 192 | $190.62 |
| 2021-05-05 | TRIZZINO, JOHN | EVP, CCO, CBO & Interim CFO | 普通株式 | 売却 | 412 | $191.53 |
| 2021-05-05 | TRIZZINO, JOHN | EVP, CCO, CBO & Interim CFO | 普通株式 | 売却 | 68 | $194.08 |
| 2021-05-05 | TRIZZINO, JOHN | EVP, CCO, CBO & Interim CFO | 普通株式 | 購入 | 2,084 | $5.95 |
| 2021-05-05 | TRIZZINO, JOHN | EVP, CCO, CBO & Interim CFO | 普通株式 | 売却 | 105 | $186.05 |
| 2021-05-05 | TRIZZINO, JOHN | EVP, CCO, CBO & Interim CFO | 普通株式 | 売却 | 186 | $187.35 |
| 2021-05-05 | TRIZZINO, JOHN | EVP, CCO, CBO & Interim CFO | 普通株式 | 売却 | 318 | $188.51 |
| 2021-05-05 | TRIZZINO, JOHN | EVP, CCO, CBO & Interim CFO | 普通株式 | 購入 | 417 | $27.60 |
| 2021-05-05 | TRIZZINO, JOHN | EVP, CCO, CBO & Interim CFO | 普通株式 | 購入 | 521 | $46.00 |
| 2021-05-05 | TRIZZINO, JOHN | EVP, CCO, CBO & Interim CFO | 普通株式 | 売却 | 72 | $163.03 |
| 2021-05-05 | TRIZZINO, JOHN | EVP, CCO, CBO & Interim CFO | 普通株式 | 売却 | 12 | $164.71 |
| 2021-05-05 | TRIZZINO, JOHN | EVP, CCO, CBO & Interim CFO | 普通株式 | 売却 | 13 | $168.34 |
| 2021-04-30 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 416 | $27.60 |
| 2021-04-30 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 416 | $46.00 |
| 2021-04-30 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 192 | $246.17 |
| 2021-04-30 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 128 | $247.32 |
| 2021-04-30 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 20 | $248.26 |
| 2021-04-30 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 購入 | 416 | $0.00 |
| 2021-04-30 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 2,063 | $5.95 |
| 2021-04-30 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 464 | $236.27 |
| 2021-04-30 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 576 | $237.06 |
| 2021-04-30 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 267 | $238.05 |
| 2021-04-30 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 447 | $239.31 |
| 2021-04-30 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 207 | $240.06 |
| 2021-04-30 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 359 | $241.81 |
| 2021-04-30 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 145 | $243.05 |
| 2021-04-30 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 59 | $243.75 |
| 2021-04-30 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 31 | $245.02 |
| 2021-04-30 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 購入 | 2,063 | $0.00 |
| 2021-04-19 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 417 | $216.11 |
| 2021-04-19 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 61 | $213.79 |
| 2021-04-19 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 134 | $215.01 |
| 2021-04-19 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 284 | $217.22 |
| 2021-04-19 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 153 | $218.48 |
| 2021-04-19 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 81 | $219.17 |
| 2021-04-19 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 437 | $220.57 |
| 2021-04-19 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 356 | $221.67 |
| 2021-04-19 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 494 | $224.50 |
| 2021-04-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 412 | $202.85 |
| 2021-04-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 391 | $204.01 |
| 2021-04-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 4,819 | $0.00 |
| 2021-04-15 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 3,124 | $0.00 |
| 2021-04-15 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 868 | $0.00 |
| 2021-04-15 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 619 | $0.00 |
| 2021-04-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 868 | $27.60 |
| 2021-04-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 873 | $197.70 |
| 2021-04-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 560 | $196.77 |
| 2021-04-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 3,124 | $5.95 |
| 2021-04-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 619 | $27.00 |
| 2021-04-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 1,101 | $46.00 |
| 2021-04-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 2,260 | $202.09 |
| 2021-04-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 142 | $202.09 |
| 2021-04-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 4,819 | $202.09 |
| 2021-04-15 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 1,101 | $0.00 |
| 2021-04-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 127 | $206.82 |
| 2021-04-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 83 | $205.69 |
| 2021-04-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 152 | $204.71 |
| 2021-04-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 717 | $198.70 |
| 2021-04-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 959 | $199.86 |
| 2021-04-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 605 | $200.77 |
| 2021-04-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 833 | $201.93 |
| 2021-04-07 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 191 | $178.03 |
| 2021-04-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 購入 | 2,083 | $5.95 |
| 2021-04-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 購入 | 417 | $27.60 |
| 2021-04-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 購入 | 521 | $46.00 |
| 2021-04-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 3,021 | $190.10 |
| 2021-04-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 購入 | 383 | $177.29 |
| 2021-04-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 13 | $177.29 |
| 2021-04-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 179 | $177.29 |
| 2021-04-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | ストックオプション | 売却 | 417 | $0.00 |
| 2021-04-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | ストックオプション | 売却 | 521 | $0.00 |
| 2021-04-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | ストックオプション | 売却 | 2,083 | $0.00 |
| 2021-04-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 383 | $0.00 |
| 2021-03-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 56 | $194.74 |
| 2021-03-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 145 | $184.59 |
| 2021-03-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 売却 | 416 | $0.00 |
| 2021-03-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 171 | $181.86 |
| 2021-03-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 168 | $181.09 |
| 2021-03-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 1,075 | $185.73 |
| 2021-03-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 164 | $187.08 |
| 2021-03-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 164 | $189.06 |
| 2021-03-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 252 | $190.10 |
| 2021-03-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 245 | $191.38 |
| 2021-03-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 151 | $192.82 |
| 2021-03-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 47 | $196.12 |
| 2021-03-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 416 | $46.00 |
| 2021-03-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 2,062 | $5.95 |
| 2021-03-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 売却 | 2,062 | $0.00 |
| 2021-03-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 416 | $27.60 |
| 2021-03-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 256 | $183.35 |
| 2021-03-25 | YOUNG, JAMES F | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2021-03-25 | YOUNG, JAMES F | Director | ストックオプション | 売却 | 37,500 | $0.00 |
| 2021-03-25 | YOUNG, JAMES F | Director | 普通株式 | 購入 | 37,500 | $3.99 |
| 2021-03-25 | YOUNG, JAMES F | Director | 普通株式 | 購入 | 10,000 | $27.60 |
| 2021-03-23 | YOUNG, JAMES F | Director | 普通株式 | 購入 | 10,000 | $46.00 |
| 2021-03-23 | YOUNG, JAMES F | Director | 普通株式 | 売却 | 4,434 | $227.43 |
| 2021-03-23 | YOUNG, JAMES F | Director | 普通株式 | 売却 | 3,120 | $228.42 |
| 2021-03-23 | YOUNG, JAMES F | Director | 普通株式 | 売却 | 2,446 | $229.41 |
| 2021-03-23 | YOUNG, JAMES F | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2021-03-19 | MCMANUS, MICHAEL A JR | Director | 普通株式 | 売却 | 1,000 | $221.40 |
| 2021-03-19 | MCMANUS, MICHAEL A JR | Director | 普通株式 | 売却 | 3,000 | $220.57 |
| 2021-03-17 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 375 | $224.78 |
| 2021-03-17 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 5 | $210.85 |
| 2021-03-17 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 57 | $211.96 |
| 2021-03-17 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 57 | $213.01 |
| 2021-03-17 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 459 | $215.19 |
| 2021-03-17 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 164 | $223.86 |
| 2021-03-17 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 60 | $221.91 |
| 2021-03-17 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 180 | $219.84 |
| 2021-03-17 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 114 | $218.53 |
| 2021-03-17 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 402 | $217.31 |
| 2021-03-17 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 421 | $216.05 |
| 2021-03-17 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 129 | $225.89 |
| 2021-03-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 868 | $27.60 |
| 2021-03-15 | EVANS, GARY C | Director | ストックオプション | 売却 | 18,000 | $0.00 |
| 2021-03-15 | EVANS, GARY C | Director | ストックオプション | 売却 | 4,500 | $0.00 |
| 2021-03-15 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 868 | $0.00 |
| 2021-03-15 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 1,101 | $0.00 |
| 2021-03-15 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 3,124 | $0.00 |
| 2021-03-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 4,819 | $0.00 |
| 2021-03-15 | EVANS, GARY C | Director | ストックオプション | 売却 | 2,000 | $0.00 |
| 2021-03-15 | EVANS, GARY C | Director | 普通株式 | 売却 | 14,768 | $212.00 |
| 2021-03-15 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 619 | $0.00 |
| 2021-03-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 619 | $27.00 |
| 2021-03-15 | EVANS, GARY C | Director | 普通株式 | 売却 | 9,732 | $210.00 |
| 2021-03-15 | EVANS, GARY C | Director | 普通株式 | 購入 | 18,000 | $3.99 |
| 2021-03-15 | EVANS, GARY C | Director | 普通株式 | 購入 | 4,500 | $46.00 |
| 2021-03-15 | EVANS, GARY C | Director | 普通株式 | 購入 | 2,000 | $99.80 |
| 2021-03-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 1,101 | $46.00 |
| 2021-03-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 3,124 | $5.95 |
| 2021-03-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 901 | $196.88 |
| 2021-03-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,939 | $197.87 |
| 2021-03-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,490 | $199.07 |
| 2021-03-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,282 | $200.14 |
| 2021-03-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 100 | $201.47 |
| 2021-03-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 4,819 | $217.46 |
| 2021-03-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 132 | $217.46 |
| 2021-03-15 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 2,264 | $217.46 |
| 2021-03-09 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 190 | $168.09 |
| 2021-03-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | ストックオプション | 売却 | 417 | $0.00 |
| 2021-03-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 186 | $173.54 |
| 2021-03-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 72 | $150.31 |
| 2021-03-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 263 | $166.48 |
| 2021-03-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 162 | $163.53 |
| 2021-03-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 150 | $152.39 |
| 2021-03-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 172 | $160.82 |
| 2021-03-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 101 | $159.02 |
| 2021-03-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 160 | $157.08 |
| 2021-03-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 135 | $155.64 |
| 2021-03-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 185 | $154.00 |
| 2021-03-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 312 | $153.24 |
| 2021-03-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 購入 | 417 | $27.60 |
| 2021-03-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 購入 | 521 | $46.00 |
| 2021-03-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 購入 | 2,083 | $5.95 |
| 2021-03-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 383 | $0.00 |
| 2021-03-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | ストックオプション | 売却 | 2,083 | $0.00 |
| 2021-03-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | ストックオプション | 売却 | 521 | $0.00 |
| 2021-03-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 179 | $174.84 |
| 2021-03-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 14 | $174.84 |
| 2021-03-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 購入 | 383 | $5.95 |
| 2021-03-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 12 | $175.16 |
| 2021-03-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 203 | $172.24 |
| 2021-03-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 314 | $171.23 |
| 2021-03-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 336 | $170.25 |
| 2021-03-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 91 | $168.89 |
| 2021-03-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 167 | $167.73 |
| 2021-02-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 120 | $224.93 |
| 2021-02-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 168 | $220.33 |
| 2021-02-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 59 | $231.40 |
| 2021-02-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 売却 | 2,063 | $0.00 |
| 2021-02-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 売却 | 416 | $0.00 |
| 2021-02-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 12 | $232.35 |
| 2021-02-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 38 | $230.04 |
| 2021-02-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 369 | $228.64 |
| 2021-02-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 569 | $227.82 |
| 2021-02-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 2,063 | $5.95 |
| 2021-02-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 538 | $226.59 |
| 2021-02-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 248 | $225.45 |
| 2021-02-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 416 | $46.00 |
| 2021-02-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 416 | $27.60 |
| 2021-02-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 109 | $219.55 |
| 2021-02-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 250 | $221.32 |
| 2021-02-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 227 | $222.39 |
| 2021-02-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 188 | $223.48 |
| 2021-02-18 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 67 | $273.61 |
| 2021-02-18 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 32 | $276.23 |
| 2021-02-18 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 65 | $278.27 |
| 2021-02-18 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 73 | $279.20 |
| 2021-02-18 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 48 | $274.63 |
| 2021-02-18 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 80 | $264.09 |
| 2021-02-18 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 361 | $265.52 |
| 2021-02-18 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 128 | $266.68 |
| 2021-02-18 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 268 | $268.19 |
| 2021-02-18 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 678 | $269.23 |
| 2021-02-18 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 319 | $269.93 |
| 2021-02-18 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 110 | $271.16 |
| 2021-02-18 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 205 | $272.43 |
| 2021-02-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 4,819 | $5.95 |
| 2021-02-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 66 | $296.58 |
| 2021-02-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 13 | $294.05 |
| 2021-02-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 1,101 | $46.00 |
| 2021-02-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 110 | $262.70 |
| 2021-02-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 619 | $27.00 |
| 2021-02-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 868 | $27.60 |
| 2021-02-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 3,124 | $5.95 |
| 2021-02-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 138 | $272.42 |
| 2021-02-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 137 | $273.39 |
| 2021-02-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 225 | $274.80 |
| 2021-02-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 129 | $275.83 |
| 2021-02-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 377 | $277.09 |
| 2021-02-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 236 | $278.98 |
| 2021-02-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 156 | $280.71 |
| 2021-02-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 522 | $281.64 |
| 2021-02-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 653 | $282.13 |
| 2021-02-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 955 | $283.43 |
| 2021-02-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,204 | $284.25 |
| 2021-02-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 59 | $285.30 |
| 2021-02-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 148 | $286.26 |
| 2021-02-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 147 | $287.41 |
| 2021-02-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 9 | $288.80 |
| 2021-02-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 125 | $289.89 |
| 2021-02-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 2,275 | $262.70 |
| 2021-02-16 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 619 | $0.00 |
| 2021-02-16 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 868 | $0.00 |
| 2021-02-16 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 1,101 | $0.00 |
| 2021-02-16 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 3,124 | $0.00 |
| 2021-02-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 4,819 | $0.00 |
| 2021-02-16 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 413 | $291.57 |
| 2021-02-09 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 194 | $324.50 |
| 2021-02-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 30 | $297.82 |
| 2021-02-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 25 | $298.80 |
| 2021-02-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 182 | $290.18 |
| 2021-02-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 104 | $296.96 |
| 2021-02-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | ストックオプション | 売却 | 417 | $0.00 |
| 2021-02-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | ストックオプション | 売却 | 521 | $0.00 |
| 2021-02-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | ストックオプション | 売却 | 2,084 | $0.00 |
| 2021-02-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 384 | $0.00 |
| 2021-02-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 238 | $296.01 |
| 2021-02-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 購入 | 384 | $5.95 |
| 2021-02-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 30 | $287.03 |
| 2021-02-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 25 | $284.82 |
| 2021-02-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 1,020 | $283.50 |
| 2021-02-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 19 | $282.00 |
| 2021-02-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 購入 | 2,084 | $5.95 |
| 2021-02-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 購入 | 521 | $46.00 |
| 2021-02-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 購入 | 417 | $27.60 |
| 2021-02-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 625 | $295.05 |
| 2021-02-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 405 | $293.96 |
| 2021-02-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 272 | $292.91 |
| 2021-02-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 117 | $291.79 |
| 2021-02-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 57 | $290.86 |
| 2021-02-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 55 | $289.45 |
| 2021-02-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 8 | $290.18 |
| 2021-02-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 2,214 | $27.00 |
| 2021-02-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 売却 | 2,080 | $0.00 |
| 2021-02-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 売却 | 2,085 | $0.00 |
| 2021-02-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 2,200 | $242.20 |
| 2021-02-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 3,754 | $243.25 |
| 2021-02-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 394 | $27.00 |
| 2021-02-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 2,085 | $27.60 |
| 2021-02-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 2,080 | $46.00 |
| 2021-02-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 8,249 | $5.95 |
| 2021-02-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 1,443 | $239.04 |
| 2021-02-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 4,294 | $240.43 |
| 2021-02-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 3,331 | $241.51 |
| 2021-02-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 売却 | 394 | $0.00 |
| 2021-02-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 売却 | 2,214 | $0.00 |
| 2021-02-01 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 売却 | 8,249 | $0.00 |
| 2021-01-25 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 73 | $128.60 |
| 2021-01-07 | TRIZZINO, JOHN | EVP, CMO and CBO | 普通株式 | 売却 | 506 | $124.17 |
| 2021-01-05 | TRIZZINO, JOHN | EVP, CMO and CBO | ストックオプション | 売却 | 2,214 | $0.00 |
| 2021-01-05 | TRIZZINO, JOHN | EVP, CMO and CBO | ストックオプション | 売却 | 1,668 | $0.00 |
| 2021-01-05 | TRIZZINO, JOHN | EVP, CMO and CBO | ストックオプション | 売却 | 2,082 | $0.00 |
| 2021-01-05 | TRIZZINO, JOHN | EVP, CMO and CBO | ストックオプション | 売却 | 6,249 | $0.00 |
| 2021-01-05 | TRIZZINO, JOHN | EVP, CMO and CBO | 普通株式 | 売却 | 1,149 | $0.00 |
| 2021-01-05 | TRIZZINO, JOHN | EVP, CMO and CBO | 普通株式 | 購入 | 394 | $27.00 |
| 2021-01-05 | TRIZZINO, JOHN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 511 | $116.24 |
| 2021-01-05 | TRIZZINO, JOHN | EVP, CMO and CBO | 普通株式 | 購入 | 2,214 | $27.00 |
| 2021-01-05 | TRIZZINO, JOHN | EVP, CMO and CBO | 普通株式 | 購入 | 1,668 | $27.60 |
| 2021-01-05 | TRIZZINO, JOHN | EVP, CMO and CBO | 普通株式 | 購入 | 2,082 | $46.00 |
| 2021-01-05 | TRIZZINO, JOHN | EVP, CMO and CBO | 普通株式 | 購入 | 6,249 | $5.95 |
| 2021-01-05 | TRIZZINO, JOHN | EVP, CMO and CBO | 普通株式 | 売却 | 3,700 | $110.25 |
| 2021-01-05 | TRIZZINO, JOHN | EVP, CMO and CBO | 普通株式 | 売却 | 4,164 | $111.19 |
| 2021-01-05 | TRIZZINO, JOHN | EVP, CMO and CBO | 普通株式 | 売却 | 4,194 | $112.19 |
| 2021-01-05 | TRIZZINO, JOHN | EVP, CMO and CBO | 普通株式 | 売却 | 3,500 | $113.29 |
| 2021-01-05 | TRIZZINO, JOHN | EVP, CMO and CBO | 普通株式 | 売却 | 1,500 | $114.25 |
| 2021-01-05 | TRIZZINO, JOHN | EVP, CMO and CBO | 普通株式 | 売却 | 349 | $115.11 |
| 2021-01-05 | TRIZZINO, JOHN | EVP, CMO and CBO | 普通株式 | 購入 | 1,149 | $5.95 |
| 2021-01-05 | TRIZZINO, JOHN | EVP, CMO and CBO | 普通株式 | 売却 | 584 | $116.24 |
| 2021-01-05 | TRIZZINO, JOHN | EVP, CMO and CBO | 普通株式 | 売却 | 59 | $116.24 |
| 2021-01-05 | TRIZZINO, JOHN | EVP, CMO and CBO | ストックオプション | 売却 | 394 | $0.00 |
| 2021-01-01 | YOUNG, JAMES F | Director | 普通株式 | 購入 | 10,000 | $ |
| 2021-01-01 | YOUNG, JAMES F | Director | 譲渡制限付株式ユニット | 売却 | 10,000 | $0.00 |
| 2020-12-31 | DOUGLAS, RICHARD | Director | 普通株式 | 購入 | 1,000 | $50.00 |
| 2020-12-31 | YOUNG, JAMES F | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2020-12-31 | YOUNG, JAMES F | Director | ストックオプション | 売却 | 1,000 | $0.00 |
| 2020-12-31 | YOUNG, JAMES F | Director | 普通株式 | 売却 | 2,000 | $113.60 |
| 2020-12-31 | YOUNG, JAMES F | Director | 普通株式 | 売却 | 9,000 | $112.98 |
| 2020-12-31 | YOUNG, JAMES F | Director | 普通株式 | 購入 | 10,000 | $51.40 |
| 2020-12-31 | YOUNG, JAMES F | Director | 普通株式 | 購入 | 1,000 | $50.00 |
| 2020-12-31 | DOUGLAS, RICHARD | Director | ストックオプション | 売却 | 1,000 | $0.00 |
| 2020-12-14 | TRIZZINO, JOHN | EVP, CMO and CBO | 譲渡制限付株式ユニット | 購入 | 4,800 | $0.00 |
| 2020-12-14 | GLENN, GREGORY M | President, R&D | ストックオプション | 購入 | 18,700 | $0.00 |
| 2020-12-14 | GLENN, GREGORY M | President, R&D | 譲渡制限付株式ユニット | 購入 | 9,300 | $0.00 |
| 2020-12-14 | ERCK, STANLEY C | Director, President and CEO | 譲渡制限付株式ユニット | 購入 | 20,900 | $0.00 |
| 2020-12-14 | TRIZZINO, JOHN | EVP, CMO and CBO | ストックオプション | 購入 | 9,500 | $0.00 |
| 2020-12-14 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 購入 | 12,700 | $0.00 |
| 2020-12-14 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 譲渡制限付株式ユニット | 購入 | 6,300 | $0.00 |
| 2020-12-14 | ERCK, STANLEY C | Director, President and CEO | ストックオプション | 購入 | 41,700 | $0.00 |
| 2020-12-07 | MCGLYNN, MARGARET G | Director | ストックオプション | 購入 | 7,700 | $0.00 |
| 2020-12-05 | YOUNG, JAMES F | Director | 譲渡制限付株式ユニット | 購入 | 20,000 | $0.00 |
| 2020-11-16 | COVINO, GREGORY F | EVP, Chief Financial Officer | ストックオプション | 購入 | 8,200 | $0.00 |
| 2020-11-16 | ERCK, STANLEY C | Director, President and CEO | ストックオプション | 売却 | 9,818 | $0.00 |
| 2020-11-16 | ERCK, STANLEY C | Director, President and CEO | ストックオプション | 売却 | 42,499 | $0.00 |
| 2020-11-16 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 4,909 | $93.56 |
| 2020-11-16 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 17,503 | $92.97 |
| 2020-11-16 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 4,598 | $90.61 |
| 2020-11-16 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 購入 | 42,499 | $39.80 |
| 2020-11-16 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 8,306 | $88.36 |
| 2020-11-16 | COVINO, GREGORY F | EVP, Chief Financial Officer | 譲渡制限付株式ユニット | 購入 | 7,300 | $0.00 |
| 2020-11-16 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 5,766 | $87.20 |
| 2020-11-16 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 11,234 | $89.26 |
| 2020-11-16 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 購入 | 9,818 | $25.60 |
| 2020-10-31 | ALTON, GREGG H | Director | ストックオプション | 購入 | 7,700 | $0.00 |
| 2020-10-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 2 | $108.57 |
| 2020-09-30 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 800 | $114.73 |
| 2020-09-30 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 5,138 | $108.56 |
| 2020-09-30 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 1,500 | $109.54 |
| 2020-09-30 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 1,676 | $110.54 |
| 2020-09-30 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 900 | $111.41 |
| 2020-09-30 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 58 | $112.78 |
| 2020-09-30 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 160 | $112.03 |
| 2020-09-30 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 945 | $108.57 |
| 2020-09-30 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 79 | $107.60 |
| 2020-09-30 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 700 | $114.20 |
| 2020-09-30 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 353 | $109.59 |
| 2020-09-30 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 100 | $115.65 |
| 2020-09-30 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 332 | $110.85 |
| 2020-09-30 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 517 | $107.56 |
| 2020-09-30 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 109 | $115.08 |
| 2020-09-30 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 214 | $114.03 |
| 2020-09-30 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 100 | $115.43 |
| 2020-09-30 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 800 | $112.65 |
| 2020-09-29 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 2,432 | $109.12 |
| 2020-09-29 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 1,000 | $106.22 |
| 2020-09-29 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 1,000 | $107.25 |
| 2020-09-29 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 1,112 | $108.40 |
| 2020-09-29 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 1,000 | $109.25 |
| 2020-09-29 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 5,975 | $106.18 |
| 2020-09-29 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 7,061 | $107.30 |
| 2020-09-29 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 3,419 | $108.39 |
| 2020-09-29 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 1,574 | $109.28 |
| 2020-09-29 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 9,915 | $106.17 |
| 2020-09-29 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 5,789 | $107.30 |
| 2020-09-29 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 3,145 | $108.39 |
| 2020-09-29 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,100 | $109.21 |
| 2020-09-29 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 5,485 | $106.04 |
| 2020-09-29 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 5,653 | $107.05 |
| 2020-09-29 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 4,751 | $108.08 |
| 2020-09-28 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 551.38 | $117.07 |
| 2020-09-28 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 719.55 | $113.02 |
| 2020-09-28 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 396.99 | $113.81 |
| 2020-09-28 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 992.48 | $115.23 |
| 2020-09-28 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 941.12 | $116.08 |
| 2020-09-28 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 545.86 | $117.07 |
| 2020-09-28 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,002.51 | $115.23 |
| 2020-09-28 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 購入 | 25,000 | $5.95 |
| 2020-09-28 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 1,338 | $111.18 |
| 2020-09-28 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 11,429 | $111.18 |
| 2020-09-28 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 275.69 | $107.22 |
| 2020-09-28 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 3,739.1 | $108.20 |
| 2020-09-28 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 401 | $113.81 |
| 2020-09-28 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 726.82 | $113.02 |
| 2020-09-28 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 215.54 | $111.92 |
| 2020-09-28 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 2,343.11 | $110.97 |
| 2020-09-28 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 8,132.83 | $109.98 |
| 2020-09-28 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 6,661.4 | $109.07 |
| 2020-09-28 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 950.63 | $116.08 |
| 2020-09-28 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 25,000 | $0.00 |
| 2020-09-28 | ERCK, STANLEY C | Director, President and CEO | ストックオプション | 売却 | 25,000 | $0.00 |
| 2020-09-28 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 551.38 | $117.07 |
| 2020-09-28 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 950.63 | $116.08 |
| 2020-09-28 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 24,750 | $5.95 |
| 2020-09-28 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 272.93 | $107.22 |
| 2020-09-28 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 3,701.71 | $108.20 |
| 2020-09-28 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 6,594.79 | $109.07 |
| 2020-09-28 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 8,051.5 | $109.98 |
| 2020-09-28 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 2,319.68 | $110.97 |
| 2020-09-28 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 売却 | 24,750 | $0.00 |
| 2020-09-28 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 25,000 | $5.95 |
| 2020-09-28 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 275.69 | $107.22 |
| 2020-09-28 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 3,739.1 | $108.20 |
| 2020-09-28 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 6,661.4 | $109.07 |
| 2020-09-28 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 8,132.83 | $109.98 |
| 2020-09-28 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 2,343.11 | $110.97 |
| 2020-09-28 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 215.54 | $111.92 |
| 2020-09-28 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 726.82 | $113.02 |
| 2020-09-28 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 401 | $113.81 |
| 2020-09-28 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 213.38 | $111.92 |
| 2020-09-28 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 25,000 | $0.00 |
| 2020-09-28 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 購入 | 25,000 | $5.95 |
| 2020-09-28 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 購入 | 4,600 | $5.95 |
| 2020-09-28 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 247 | $111.18 |
| 2020-09-28 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 2,103 | $111.18 |
| 2020-09-28 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 275.69 | $107.22 |
| 2020-09-28 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 3,739.1 | $108.20 |
| 2020-09-28 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 6,661.4 | $109.07 |
| 2020-09-28 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 8,132.83 | $109.98 |
| 2020-09-28 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 2,343.11 | $110.97 |
| 2020-09-28 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 215.54 | $111.92 |
| 2020-09-28 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 726.82 | $113.02 |
| 2020-09-28 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 401 | $113.81 |
| 2020-09-28 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 1,002.51 | $115.23 |
| 2020-09-28 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 950.63 | $116.08 |
| 2020-09-28 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 551.38 | $117.07 |
| 2020-09-28 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 1,002.51 | $115.23 |
| 2020-09-28 | TRIZZINO, JOHN | EVP, CBO and CFO | ストックオプション | 売却 | 25,000 | $0.00 |
| 2020-09-28 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 4,600 | $0.00 |
| 2020-09-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 30,900 | $ |
| 2020-09-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 1,919 | $113.56 |
| 2020-09-26 | TRIZZINO, JOHN | EVP, CBO and CFO | 譲渡制限付株式ユニット | 売却 | 3,538 | $0.00 |
| 2020-09-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 3,973 | $ |
| 2020-09-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 14,925 | $113.56 |
| 2020-09-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 38,588 | $ |
| 2020-09-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 18,639 | $113.56 |
| 2020-09-26 | GLENN, GREGORY M | President, R&D | 譲渡制限付株式ユニット | 売却 | 38,588 | $0.00 |
| 2020-09-26 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 2,434 | $113.56 |
| 2020-09-26 | ERCK, STANLEY C | Director, President and CEO | 譲渡制限付株式ユニット | 売却 | 6,546 | $0.00 |
| 2020-09-26 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 購入 | 31,900 | $ |
| 2020-09-26 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 15,408 | $113.56 |
| 2020-09-26 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 購入 | 6,546 | $ |
| 2020-09-26 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 購入 | 3,538 | $ |
| 2020-09-26 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 1,709 | $113.56 |
| 2020-09-26 | TRIZZINO, JOHN | EVP, CBO and CFO | 譲渡制限付株式ユニット | 売却 | 31,900 | $0.00 |
| 2020-09-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 譲渡制限付株式ユニット | 売却 | 3,973 | $0.00 |
| 2020-09-26 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 譲渡制限付株式ユニット | 売却 | 30,900 | $0.00 |
| 2020-08-24 | GLENN, GREGORY M | President, R&D | ストックオプション | 購入 | 165,000 | $0.00 |
| 2020-08-24 | TRIZZINO, JOHN | EVP, CBO and CFO | ストックオプション | 購入 | 140,000 | $0.00 |
| 2020-08-24 | ERCK, STANLEY C | Director, President and CEO | ストックオプション | 購入 | 400,000 | $0.00 |
| 2020-08-24 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 購入 | 125,000 | $0.00 |
| 2020-08-18 | EVANS, GARY C | Director | ストックオプション | 売却 | 1,000 | $0.00 |
| 2020-08-18 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 購入 | 11,249 | $99.80 |
| 2020-08-18 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 購入 | 5,855 | $27.00 |
| 2020-08-18 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 購入 | 1,952 | $27.00 |
| 2020-08-18 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 購入 | 13,322 | $27.60 |
| 2020-08-18 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 購入 | 10,410 | $46.00 |
| 2020-08-18 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 776 | $142.85 |
| 2020-08-18 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 300 | $143.99 |
| 2020-08-18 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 4,900 | $146.21 |
| 2020-08-18 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 8,094 | $146.95 |
| 2020-08-18 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 9,101 | $147.99 |
| 2020-08-18 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 6,600 | $149.08 |
| 2020-08-18 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 1,800 | $149.83 |
| 2020-08-18 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 4,010 | $150.85 |
| 2020-08-18 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 4,199 | $152.22 |
| 2020-08-18 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 1,708 | $153.16 |
| 2020-08-18 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 売却 | 1,300 | $153.95 |
| 2020-08-18 | TRIZZINO, JOHN | EVP, CBO and CFO | ストックオプション | 売却 | 11,249 | $0.00 |
| 2020-08-18 | TRIZZINO, JOHN | EVP, CBO and CFO | ストックオプション | 売却 | 5,855 | $0.00 |
| 2020-08-18 | TRIZZINO, JOHN | EVP, CBO and CFO | ストックオプション | 売却 | 1,952 | $0.00 |
| 2020-08-18 | TRIZZINO, JOHN | EVP, CBO and CFO | ストックオプション | 売却 | 13,322 | $0.00 |
| 2020-08-18 | TRIZZINO, JOHN | EVP, CBO and CFO | ストックオプション | 売却 | 10,410 | $0.00 |
| 2020-08-18 | MCMANUS, MICHAEL A JR | Director | 普通株式 | 購入 | 4,000 | $27.60 |
| 2020-08-18 | MCMANUS, MICHAEL A JR | Director | 普通株式 | 売却 | 8,000 | $146.00 |
| 2020-08-18 | MCMANUS, MICHAEL A JR | Director | ストックオプション | 売却 | 4,000 | $0.00 |
| 2020-08-18 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 1,000 | $50.00 |
| 2020-08-18 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 7,499 | $36.60 |
| 2020-08-18 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 2,499 | $91.00 |
| 2020-08-18 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 11,249 | $99.80 |
| 2020-08-18 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 393 | $27.00 |
| 2020-08-18 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 1,952 | $27.00 |
| 2020-08-18 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 13,322 | $27.60 |
| 2020-08-18 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 購入 | 8,328 | $46.00 |
| 2020-08-18 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 24,594 | $143.92 |
| 2020-08-18 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 普通株式 | 売却 | 21,648 | $144.79 |
| 2020-08-18 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 売却 | 1,000 | $0.00 |
| 2020-08-18 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 売却 | 7,499 | $0.00 |
| 2020-08-18 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 売却 | 2,499 | $0.00 |
| 2020-08-18 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 売却 | 11,249 | $0.00 |
| 2020-08-18 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 売却 | 393 | $0.00 |
| 2020-08-18 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 売却 | 1,952 | $0.00 |
| 2020-08-18 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 売却 | 13,322 | $0.00 |
| 2020-08-18 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 売却 | 8,328 | $0.00 |
| 2020-08-18 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 3,200 | $50.00 |
| 2020-08-18 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 7,500 | $25.60 |
| 2020-08-18 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 4,405 | $36.60 |
| 2020-08-18 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 3,200 | $0.00 |
| 2020-08-18 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 7,500 | $0.00 |
| 2020-08-18 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 4,405 | $0.00 |
| 2020-08-18 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 8,200 | $0.00 |
| 2020-08-18 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 2,733 | $0.00 |
| 2020-08-18 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 16,658 | $0.00 |
| 2020-08-18 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 13,225 | $0.00 |
| 2020-08-18 | EVANS, GARY C | Director | 普通株式 | 購入 | 1,000 | $50.00 |
| 2020-08-18 | EVANS, GARY C | Director | 普通株式 | 購入 | 1,500 | $36.60 |
| 2020-08-18 | EVANS, GARY C | Director | 普通株式 | 購入 | 4,000 | $27.60 |
| 2020-08-18 | EVANS, GARY C | Director | 普通株式 | 売却 | 10,500 | $150.44 |
| 2020-08-18 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 8,200 | $27.00 |
| 2020-08-18 | EVANS, GARY C | Director | ストックオプション | 売却 | 1,500 | $0.00 |
| 2020-08-18 | EVANS, GARY C | Director | ストックオプション | 売却 | 4,000 | $0.00 |
| 2020-08-18 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 2,733 | $27.00 |
| 2020-08-18 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 16,658 | $27.60 |
| 2020-08-18 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 13,225 | $46.00 |
| 2020-08-18 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 6,288 | $143.94 |
| 2020-08-18 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 31,957 | $145.00 |
| 2020-08-18 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 17,151 | $146.00 |
| 2020-08-18 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 525 | $146.58 |
| 2020-08-18 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 1,528 | $0.00 |
| 2020-06-25 | KING, RACHEL K. | Director | ストックオプション | 購入 | 6,900 | $0.00 |
| 2020-06-25 | ERCK, STANLEY C | Director, President and CEO | ストックオプション | 購入 | 100,000 | $0.00 |
| 2020-06-25 | KING, RACHEL K. | Director | 譲渡制限付株式ユニット | 購入 | 3,450 | $0.00 |
| 2020-06-25 | GLENN, GREGORY M | President, R&D | ストックオプション | 購入 | 100,000 | $0.00 |
| 2020-06-25 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | 譲渡制限付株式ユニット | 購入 | 2,500 | $0.00 |
| 2020-06-25 | MCMANUS, MICHAEL A JR | Director | 譲渡制限付株式ユニット | 購入 | 3,450 | $0.00 |
| 2020-06-25 | EVANS, GARY C | Director | ストックオプション | 購入 | 6,900 | $0.00 |
| 2020-06-25 | TRIZZINO, JOHN | EVP, CBO and CFO | ストックオプション | 購入 | 100,000 | $0.00 |
| 2020-06-25 | DOUGLAS, RICHARD | Director | ストックオプション | 購入 | 6,900 | $0.00 |
| 2020-06-25 | HERRMANN, JOHN A III | EVP, Chief Legal Officer | ストックオプション | 購入 | 99,000 | $0.00 |
| 2020-06-25 | MOTT, DAVID M | Director | ストックオプション | 購入 | 4,400 | $0.00 |
| 2020-06-25 | MCMANUS, MICHAEL A JR | Director | ストックオプション | 購入 | 6,900 | $0.00 |
| 2020-06-25 | EVANS, GARY C | Director | 譲渡制限付株式ユニット | 購入 | 3,450 | $0.00 |
| 2020-06-25 | DOUGLAS, RICHARD | Director | 譲渡制限付株式ユニット | 購入 | 3,450 | $0.00 |
| 2020-06-25 | YOUNG, JAMES F | Director | ストックオプション | 購入 | 15,180 | $0.00 |
| 2020-06-25 | YOUNG, JAMES F | Director | 譲渡制限付株式ユニット | 購入 | 7,590 | $0.00 |
| 2020-06-25 | TRIZZINO, JOHN | EVP, CBO and CFO | 譲渡制限付株式ユニット | 購入 | 2,500 | $0.00 |
| 2020-06-18 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 16,749 | $59.53 |
| 2020-06-18 | GLENN, GREGORY M | President, R&D | ストックオプション | 売却 | 16,749 | $0.00 |
| 2020-06-18 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 16,749 | $42.20 |
| 2020-06-16 | MOTT, DAVID M | Director | ストックオプション | 購入 | 8,000 | $0.00 |
| 2020-06-03 | YOUNG, JAMES F | Director | 普通株式 | 購入 | 1,500 | $48.83 |
| 2020-05-18 | HERRMANN, JOHN A III | SVP, General Counsel | 普通株式 | 売却 | 7,499 | $49.44 |
| 2020-05-18 | HERRMANN, JOHN A III | SVP, General Counsel | 普通株式 | 購入 | 5,462 | $27.00 |
| 2020-05-18 | HERRMANN, JOHN A III | SVP, General Counsel | 普通株式 | 売却 | 5,462 | $49.44 |
| 2020-05-18 | HERRMANN, JOHN A III | SVP, General Counsel | ストックオプション | 売却 | 5,462 | $0.00 |
| 2020-05-18 | HERRMANN, JOHN A III | SVP, General Counsel | ストックオプション | 売却 | 7,499 | $0.00 |
| 2020-05-18 | HERRMANN, JOHN A III | SVP, General Counsel | 普通株式 | 購入 | 7,499 | $25.60 |
| 2020-03-08 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 1,992 | $12.48 |
| 2020-03-08 | HERRMANN, JOHN A III | SVP, General Counsel | 普通株式 | 購入 | 449 | $ |
| 2020-03-08 | HERRMANN, JOHN A III | SVP, General Counsel | 普通株式 | 売却 | 174 | $12.48 |
| 2020-03-08 | HERRMANN, JOHN A III | SVP, General Counsel | 譲渡制限付株式ユニット | 売却 | 449 | $0.00 |
| 2020-03-08 | TRIZZINO, JOHN | SVP, CBO and CFO | 普通株式 | 購入 | 468 | $ |
| 2020-03-08 | TRIZZINO, JOHN | SVP, CBO and CFO | 普通株式 | 売却 | 181 | $12.48 |
| 2020-03-08 | TRIZZINO, JOHN | SVP, CBO and CFO | 譲渡制限付株式ユニット | 売却 | 468 | $0.00 |
| 2020-03-08 | ERCK, STANLEY C | Director, President and CEO | 譲渡制限付株式ユニット | 売却 | 6,072 | $0.00 |
| 2020-03-08 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 購入 | 6,072 | $ |
| 2020-03-08 | GLENN, GREGORY M | President, R&D | 譲渡制限付株式ユニット | 売却 | 760 | $0.00 |
| 2020-03-08 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 294 | $12.48 |
| 2020-03-08 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 760 | $ |
| 2020-01-31 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 1,250 | $3.86 |
| 2019-12-12 | EVANS, GARY C | Director | ストックオプション | 購入 | 18,000 | $0.00 |
| 2019-12-12 | DOUGLAS, RICHARD | Director | ストックオプション | 購入 | 18,000 | $0.00 |
| 2019-12-12 | KING, RACHEL K. | Director | ストックオプション | 購入 | 18,000 | $0.00 |
| 2019-12-12 | MCMANUS, MICHAEL A JR | Director | ストックオプション | 購入 | 18,000 | $0.00 |
| 2019-12-12 | YOUNG, JAMES F | Director | ストックオプション | 購入 | 40,000 | $0.00 |
| 2019-12-12 | YOUNG, JAMES F | Director | ストックオプション | 購入 | 37,500 | $0.00 |
| 2019-11-18 | MCMANUS, MICHAEL A JR | Director | 普通株式 | 売却 | 3,929 | $3.82 |
| 2019-09-26 | TRIZZINO, JOHN | SVP, CBO and CFO | ストックオプション | 購入 | 100,000 | $0.00 |
| 2019-09-26 | GLENN, GREGORY M | President, R&D | ストックオプション | 購入 | 100,000 | $0.00 |
| 2019-09-26 | HERRMANN, JOHN A III | SVP, General Counsel | 譲渡制限付株式ユニット | 購入 | 30,900 | $0.00 |
| 2019-09-26 | HERRMANN, JOHN A III | SVP, General Counsel | 譲渡制限付株式ユニット | 購入 | 11,919 | $0.00 |
| 2019-09-26 | HERRMANN, JOHN A III | SVP, General Counsel | ストックオプション | 購入 | 99,000 | $0.00 |
| 2019-09-26 | ERCK, STANLEY C | Director, President and CEO | ストックオプション | 購入 | 100,000 | $0.00 |
| 2019-09-26 | ERCK, STANLEY C | Director, President and CEO | 譲渡制限付株式ユニット | 購入 | 19,638 | $0.00 |
| 2019-09-26 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 購入 | 100,000 | $0.00 |
| 2019-09-26 | TRIZZINO, JOHN | SVP, CBO and CFO | 譲渡制限付株式ユニット | 購入 | 10,613 | $0.00 |
| 2019-09-26 | TRIZZINO, JOHN | SVP, CBO and CFO | 普通株式 | 購入 | 18,400 | $0.00 |
| 2019-09-26 | GLENN, GREGORY M | President, R&D | 譲渡制限付株式ユニット | 購入 | 38,588 | $0.00 |
| 2019-09-26 | TRIZZINO, JOHN | EVP, CBO and CFO | 普通株式 | 購入 | 18,400 | $0.00 |
| 2019-09-26 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 66,100 | $0.00 |
| 2019-09-26 | TRIZZINO, JOHN | SVP, CBO and CFO | 譲渡制限付株式ユニット | 購入 | 31,900 | $0.00 |
| 2019-09-17 | HERRMANN, JOHN A III | SVP, General Counsel | 普通株式 | 売却 | 3,643 | $7.07 |
| 2019-09-13 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 9,620 | $6.18 |
| 2019-09-11 | TRIZZINO, JOHN | SVP, CBO and CFO | 普通株式 | 売却 | 5,578 | $5.72 |
| 2019-09-08 | TRIZZINO, JOHN | SVP, CBO and CFO | 普通株式 | 購入 | 5,143 | $ |
| 2019-09-08 | HERRMANN, JOHN A III | SVP, General Counsel | 普通株式 | 購入 | 4,933 | $ |
| 2019-09-08 | HERRMANN, JOHN A III | SVP, General Counsel | 普通株式 | 売却 | 1,643 | $5.50 |
| 2019-09-08 | HERRMANN, JOHN A III | SVP, General Counsel | 譲渡制限付株式ユニット | 売却 | 4,933 | $0.00 |
| 2019-09-08 | TRIZZINO, JOHN | SVP, CBO and CFO | 普通株式 | 売却 | 1,713 | $5.50 |
| 2019-09-08 | TRIZZINO, JOHN | SVP, CBO and CFO | 譲渡制限付株式ユニット | 売却 | 5,143 | $0.00 |
| 2019-09-08 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 7,608 | $ |
| 2019-09-08 | GLENN, GREGORY M | President, R&D | 普通株式 | 売却 | 2,534 | $5.50 |
| 2019-09-08 | GLENN, GREGORY M | President, R&D | 譲渡制限付株式ユニット | 売却 | 7,608 | $0.00 |
| 2019-05-13 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 1,000 | $5.85 |
| 2019-03-27 | KING, RACHEL K. | Director | 普通株式 | 購入 | 22,000 | $0.53 |
| 2019-03-27 | KING, RACHEL K. | Director | 普通株式 | 購入 | 42,000 | $0.53 |
| 2019-03-08 | TRIZZINO, JOHN | SVP, CBO and CFO | 譲渡制限付株式ユニット | 購入 | 46,887 | $0.00 |
| 2019-03-08 | ERCK, STANLEY C | Director, President and CEO | 譲渡制限付株式ユニット | 購入 | 607,248 | $0.00 |
| 2019-03-08 | GLENN, GREGORY M | President, R&D | 譲渡制限付株式ユニット | 購入 | 76,083 | $0.00 |
| 2019-03-08 | GLENN, GREGORY M | President, R&D | 譲渡制限付株式ユニット | 購入 | 152,166 | $0.00 |
| 2019-03-08 | HERRMANN, JOHN A III | SVP, General Counsel | 譲渡制限付株式ユニット | 購入 | 98,676 | $0.00 |
| 2019-03-08 | HERRMANN, JOHN A III | SVP, General Counsel | 譲渡制限付株式ユニット | 購入 | 44,979 | $0.00 |
| 2019-03-08 | TRIZZINO, JOHN | SVP, CBO and CFO | 譲渡制限付株式ユニット | 購入 | 102,861 | $0.00 |
| 2019-01-31 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 13,168 | $0.88 |
| 2018-12-13 | DOUGLAS, RICHARD | Director | ストックオプション | 購入 | 90,000 | $0.00 |
| 2018-12-13 | YOUNG, JAMES F | Director | ストックオプション | 購入 | 200,000 | $0.00 |
| 2018-12-13 | EVANS, GARY C | Director | ストックオプション | 購入 | 90,000 | $0.00 |
| 2018-12-13 | MCMANUS, MICHAEL A JR | Director | ストックオプション | 購入 | 90,000 | $0.00 |
| 2018-12-13 | TRIZZINO, JOHN | SVP, CBO and CFO | ストックオプション | 購入 | 500,000 | $0.00 |
| 2018-12-13 | HERRMANN, JOHN A III | SVP, General Counsel | ストックオプション | 購入 | 400,000 | $0.00 |
| 2018-12-13 | ERCK, STANLEY C | Director, President and CEO | ストックオプション | 購入 | 1,970,000 | $0.00 |
| 2018-12-13 | GLENN, GREGORY M | President, R&D | ストックオプション | 購入 | 635,000 | $0.00 |
| 2018-10-31 | KING, RACHEL K. | Director | ストックオプション | 購入 | 160,000 | $0.00 |
| 2018-07-31 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 13,007 | $0.88 |
| 2018-05-14 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 購入 | 100,000 | $1.65 |
| 2018-05-14 | TRIZZINO, JOHN | SVP, CBO and CFO | 普通株式 | 購入 | 50,000 | $1.64 |
| 2018-05-14 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 19,900 | $1.64 |
| 2018-05-14 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 100 | $1.64 |
| 2018-01-31 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 12,784 | $0.88 |
| 2017-12-15 | DOUGLAS, RICHARD | Director | ストックオプション | 購入 | 80,000 | $0.00 |
| 2017-12-15 | YOUNG, JAMES F | Director | ストックオプション | 購入 | 200,000 | $0.00 |
| 2017-12-15 | MCMANUS, MICHAEL A JR | Director | ストックオプション | 購入 | 80,000 | $0.00 |
| 2017-12-15 | ERCK, STANLEY C | Director, President and CEO | ストックオプション | 購入 | 1,650,000 | $0.00 |
| 2017-12-15 | GLENN, GREGORY M | President, R&D | ストックオプション | 購入 | 500,000 | $0.00 |
| 2017-12-15 | HERRMANN, JOHN A III | SVP, General Counsel | ストックオプション | 購入 | 400,000 | $0.00 |
| 2017-12-15 | TRIZZINO, JOHN | SVP, Commercial Operations | ストックオプション | 購入 | 400,000 | $0.00 |
| 2017-12-15 | EVANS, GARY C | Director | ストックオプション | 購入 | 80,000 | $0.00 |
| 2017-11-09 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 10,000 | $1.13 |
| 2017-11-09 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 購入 | 100,000 | $1.13 |
| 2017-08-31 | YOUNG, JAMES F | Director | 普通株式 | 売却 | 175,000 | $1.06 |
| 2017-07-31 | PHILLIPS, BARCLAY A | SVP, Chief Financial Officer | 普通株式 | 購入 | 2,057 | $0.89 |
| 2017-05-12 | MCMANUS, MICHAEL A JR | Director | 普通株式 | 購入 | 20,000 | $0.97 |
| 2017-05-11 | DOUGLAS, RICHARD | Director | 普通株式 | 購入 | 200,000 | $0.93 |
| 2017-05-11 | MCMANUS, MICHAEL A JR | Director | 普通株式 | 購入 | 10,000 | $0.84 |
| 2017-05-11 | PHILLIPS, BARCLAY A | SVP, Chief Financial Officer | 普通株式 | 購入 | 25,000 | $0.84 |
| 2017-05-11 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 購入 | 50,000 | $0.84 |
| 2017-03-16 | BOUDREAUX, GAIL | Director | ストックオプション | 購入 | 80,000 | $0.00 |
| 2017-03-16 | MCMANUS, MICHAEL A JR | Director | ストックオプション | 購入 | 80,000 | $0.00 |
| 2017-03-16 | EVANS, GARY C | Director | ストックオプション | 購入 | 80,000 | $0.00 |
| 2017-03-16 | YOUNG, JAMES F | Director | ストックオプション | 購入 | 200,000 | $0.00 |
| 2017-03-16 | DOUGLAS, RICHARD | Director | ストックオプション | 購入 | 80,000 | $0.00 |
| 2017-03-14 | YOUNG, JAMES F | Director | 普通株式 | 売却 | 100,000 | $1.39 |
| 2017-01-31 | HERRMANN, JOHN A III | SVP, General Counsel | 普通株式 | 購入 | 4,960 | $1.12 |
| 2017-01-31 | PHILLIPS, BARCLAY A | SVP, Chief Financial Officer | 普通株式 | 購入 | 1,633 | $1.12 |
| 2017-01-31 | TRIZZINO, JOHN | SVP, Commercial Operations | 普通株式 | 購入 | 3,401 | $1.12 |
| 2016-12-07 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 1,000 | $1.45 |
| 2016-11-14 | ERCK, STANLEY C | Director, President and CEO | ストックオプション | 購入 | 550,000 | $0.00 |
| 2016-11-14 | PHILLIPS, BARCLAY A | SVP, Chief Financial Officer | ストックオプション | 購入 | 125,000 | $0.00 |
| 2016-11-14 | HERRMANN, JOHN A III | SVP, General Counsel | ストックオプション | 購入 | 125,000 | $0.00 |
| 2016-11-14 | TRIZZINO, JOHN | SVP, Commercial Operations | ストックオプション | 購入 | 125,000 | $0.00 |
| 2016-11-14 | GLENN, GREGORY M | President, R&D | ストックオプション | 購入 | 175,000 | $0.00 |
| 2016-09-22 | TRIZZINO, JOHN | SVP, Commercial Operations | 普通株式 | 購入 | 46,000 | $2.17 |
| 2016-09-21 | MCMANUS, MICHAEL A JR | Director | 普通株式 | 購入 | 30,000 | $1.61 |
| 2016-09-21 | DOUGLAS, RICHARD | Director | 普通株式 | 購入 | 100,000 | $1.72 |
| 2016-09-21 | GLENN, GREGORY M | President, R&D | 普通株式 | 購入 | 1,000 | $1.65 |
| 2016-09-20 | BOUDREAUX, GAIL | Director | 普通株式 | 購入 | 100,000 | $1.45 |
| 2016-07-31 | PHILLIPS, BARCLAY A | SVP, Chief Financial Officer | 普通株式 | 購入 | 422 | $4.29 |
| 2016-06-06 | EVANS, GARY C | Director | 普通株式 | 売却 | 18,998 | $6.50 |
| 2016-05-24 | EVANS, GARY C | Director | 普通株式 | 売却 | 16,134 | $5.42 |
| 2016-05-23 | EVANS, GARY C | Director | 普通株式 | 売却 | 33,866 | $5.40 |
| 2016-03-31 | ERCK, STANLEY C | Director, President and CEO | ストックオプション | 売却 | 201,991 | $0.00 |
| 2016-03-31 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 226,769 | $5.18 |
| 2016-03-31 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 購入 | 201,991 | $1.28 |
| 2016-03-30 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 売却 | 198,009 | $5.19 |
| 2016-03-30 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 購入 | 198,009 | $1.28 |
| 2016-03-30 | ERCK, STANLEY C | Director, President and CEO | ストックオプション | 売却 | 198,009 | $0.00 |
| 2016-03-15 | YOUNG, JAMES F | Director | ストックオプション | 購入 | 100,000 | $0.00 |
| 2016-03-15 | EVANS, GARY C | Director | ストックオプション | 購入 | 40,000 | $0.00 |
| 2016-03-15 | TRIZZINO, JOHN | SVP, Commercial Operations | ストックオプション | 購入 | 225,000 | $0.00 |
| 2016-03-15 | HERRMANN, JOHN A III | SVP, General Counsel | ストックオプション | 購入 | 225,000 | $0.00 |
| 2016-03-15 | DOUGLAS, RICHARD | Director | ストックオプション | 購入 | 40,000 | $0.00 |
| 2016-03-15 | BOUDREAUX, GAIL | Director | ストックオプション | 購入 | 40,000 | $0.00 |
| 2016-03-15 | ERCK, STANLEY C | Director, President and CEO | ストックオプション | 購入 | 900,000 | $0.00 |
| 2016-03-15 | MCMANUS, MICHAEL A JR | Director | ストックオプション | 購入 | 40,000 | $0.00 |
| 2016-03-15 | PHILLIPS, BARCLAY A | SVP, Chief Financial Officer | ストックオプション | 購入 | 225,000 | $0.00 |
| 2016-03-15 | GLENN, GREGORY M | President, R&D | ストックオプション | 購入 | 350,000 | $0.00 |
| 2016-02-17 | EVANS, GARY C | Director | ストックオプション | 売却 | 50,000 | $0.00 |
| 2016-02-17 | EVANS, GARY C | Director | 普通株式 | 購入 | 50,000 | $4.60 |
| 2016-01-31 | ERCK, STANLEY C | Director, CEO and President | 普通株式 | 購入 | 2,072 | $4.38 |
| 2016-01-31 | PHILLIPS, BARCLAY A | SVP, Chief Financial Officer | 普通株式 | 購入 | 405 | $4.38 |
| 2016-01-31 | TRIZZINO, JOHN | SVP, Commercial Operations | 普通株式 | 購入 | 5,855 | $3.63 |
| 2016-01-31 | HERRMANN, JOHN A III | SVP, General Counsel | 普通株式 | 購入 | 2,072 | $4.38 |
| 2016-01-31 | GLENN, GREGORY M | SVP, Research and Development | 普通株式 | 購入 | 2,369 | $4.38 |
| 2015-12-16 | HERRMANN, JOHN A III | SVP, General Counsel | 普通株式 | 売却 | 27,945 | $8.64 |
| 2015-12-16 | GLENN, GREGORY M | SVP, Research and Development | 普通株式 | 売却 | 61,886 | $8.58 |
| 2015-12-16 | GLENN, GREGORY M | SVP, Research and Development | ストックオプション | 売却 | 61,886 | $0.00 |
| 2015-12-16 | GLENN, GREGORY M | SVP, Research and Development | 普通株式 | 購入 | 61,886 | $1.83 |
| 2015-08-24 | EVANS, GARY C | Director | 普通株式 | 売却 | 20,000 | $11.24 |
| 2015-08-24 | GLENN, GREGORY M | SVP, Research and Development | 普通株式 | 売却 | 1,100 | $0.00 |
| 2015-08-20 | PHILLIPS, BARCLAY A | SVP, Chief Financial Officer | 普通株式 | 売却 | 10,000 | $12.81 |
| 2015-08-19 | MCMANUS, MICHAEL A JR | Director | 普通株式 | 購入 | 30,000 | $1.83 |
| 2015-08-19 | PHILLIPS, BARCLAY A | SVP, Chief Financial Officer | 普通株式 | 売却 | 18,656 | $13.20 |
| 2015-08-19 | MCMANUS, MICHAEL A JR | Director | 普通株式 | 購入 | 20,000 | $2.50 |
| 2015-08-19 | MCMANUS, MICHAEL A JR | Director | ストックオプション | 売却 | 20,000 | $0.00 |
| 2015-08-19 | MCMANUS, MICHAEL A JR | Director | ストックオプション | 売却 | 30,000 | $0.00 |
| 2015-08-18 | GLENN, GREGORY M | SVP, Research and Development | 普通株式 | 売却 | 15,000 | $13.52 |
| 2015-08-18 | GLENN, GREGORY M | SVP, Research and Development | ストックオプション | 売却 | 15,000 | $0.00 |
| 2015-08-18 | GLENN, GREGORY M | SVP, Research and Development | 普通株式 | 購入 | 15,000 | $2.11 |
| 2015-08-13 | EVANS, GARY C | Director | ストックオプション | 売却 | 15,000 | $0.00 |
| 2015-08-13 | EVANS, GARY C | Director | 普通株式 | 購入 | 15,000 | $0.56 |
| 2015-08-13 | EVANS, GARY C | Director | 普通株式 | 購入 | 30,000 | $1.28 |
| 2015-08-13 | EVANS, GARY C | Director | 普通株式 | 売却 | 6,002 | $13.56 |
| 2015-08-13 | EVANS, GARY C | Director | ストックオプション | 売却 | 30,000 | $0.00 |
| 2015-07-31 | GLENN, GREGORY M | SVP, Research and Development | 普通株式 | 購入 | 892 | $2.28 |
| 2015-07-31 | HERRMANN, JOHN A III | SVP, General Counsel | 普通株式 | 購入 | 1,502 | $2.28 |
| 2015-07-31 | ERCK, STANLEY C | Director, CEO and President | 普通株式 | 購入 | 3,207 | $2.28 |
| 2015-07-31 | PHILLIPS, BARCLAY A | SVP, Chief Financial Officer | 普通株式 | 購入 | 764 | $2.28 |
| 2015-07-31 | TRIZZINO, JOHN | SVP, Commercial Operations | 普通株式 | 購入 | 5,098 | $3.63 |
| 2015-06-18 | YOUNG, JAMES F | Director | 普通株式 | 売却 | 50,000 | $9.47 |
| 2015-06-17 | MODI, RAJIV I. | Director | 普通株式 | 売却 | 152,768 | $9.01 |
| 2015-06-17 | BOUDREAUX, GAIL | Director | ストックオプション | 購入 | 40,000 | $0.00 |
| 2015-06-16 | MODI, RAJIV I. | Director | 普通株式 | 売却 | 280,285 | $9.01 |
| 2015-06-11 | MODI, RAJIV I. | Director | 普通株式 | 売却 | 11,185 | $9.00 |
| 2015-06-10 | MODI, RAJIV I. | Director | 普通株式 | 売却 | 297,375 | $9.01 |
| 2015-06-09 | MODI, RAJIV I. | Director | 普通株式 | 売却 | 47,531 | $8.93 |
| 2015-06-08 | MODI, RAJIV I. | Director | 普通株式 | 売却 | 206,175 | $8.93 |
| 2015-06-04 | MODI, RAJIV I. | Director | 普通株式 | 売却 | 65,589 | $8.92 |
| 2015-06-03 | MODI, RAJIV I. | Director | 普通株式 | 売却 | 355,000 | $8.92 |
| 2015-06-02 | MODI, RAJIV I. | Director | 普通株式 | 売却 | 84,092 | $8.90 |
| 2015-06-01 | MODI, RAJIV I. | Director | 普通株式 | 売却 | 1,500,000 | $8.80 |
| 2015-05-28 | MODI, RAJIV I. | Director | 普通株式 | 売却 | 2,000,000 | $8.70 |
| 2015-03-12 | GLENN, GREGORY M | SVP, Research and Development | 普通株式 | 売却 | 600 | $0.00 |
| 2015-03-05 | MCMANUS, MICHAEL A JR | Director | ストックオプション | 購入 | 40,000 | $0.00 |
| 2015-03-05 | DOUGLAS, RICHARD | Director | ストックオプション | 購入 | 40,000 | $0.00 |
| 2015-03-05 | EVANS, GARY C | Director | ストックオプション | 購入 | 40,000 | $0.00 |
| 2015-03-05 | WILSON, RUSSELL P | SVP, Business Development | ストックオプション | 購入 | 200,000 | $0.00 |
| 2015-03-05 | HERRMANN, JOHN A III | SVP, General Counsel | ストックオプション | 購入 | 200,000 | $0.00 |
| 2015-03-05 | ERCK, STANLEY C | Director, CEO and President | ストックオプション | 購入 | 900,000 | $0.00 |
| 2015-03-05 | GLENN, GREGORY M | SVP, Research and Development | ストックオプション | 購入 | 300,000 | $0.00 |
| 2015-03-05 | PHILLIPS, BARCLAY A | SVP, Chief Financial Officer | ストックオプション | 購入 | 200,000 | $0.00 |
| 2015-03-05 | HAHN, TIMOTHY JON | SVP, Manufacturing | ストックオプション | 購入 | 150,000 | $0.00 |
| 2015-03-05 | YOUNG, JAMES F | Director | ストックオプション | 購入 | 100,000 | $0.00 |
| 2015-03-05 | TRIZZINO, JOHN | SVP, Commercial Operations | ストックオプション | 購入 | 200,000 | $0.00 |
| 2015-02-20 | MCMANUS, MICHAEL A JR | Director | 普通株式 | 購入 | 15,000 | $2.35 |
| 2015-02-20 | MCMANUS, MICHAEL A JR | Director | 普通株式 | 購入 | 15,000 | $1.48 |
| 2015-02-20 | MCMANUS, MICHAEL A JR | Director | 普通株式 | 購入 | 15,000 | $2.61 |
| 2015-02-20 | MCMANUS, MICHAEL A JR | Director | ストックオプション | 売却 | 15,000 | $0.00 |
| 2015-01-31 | HAHN, TIMOTHY JON | SVP, Manufacturing | 普通株式 | 購入 | 9,329 | $2.28 |
| 2015-01-31 | WILSON, RUSSELL P | SVP, Business Development | 普通株式 | 購入 | 5,050 | $2.28 |
| 2015-01-31 | TRIZZINO, JOHN | SVP, Commercial Operations | 普通株式 | 購入 | 6,611 | $3.63 |
| 2015-01-31 | ERCK, STANLEY C | Director, CEO and President | 普通株式 | 購入 | 6,122 | $2.28 |
| 2015-01-31 | PHILLIPS, BARCLAY A | SVP, Chief Financial Officer | 普通株式 | 購入 | 8,388 | $2.28 |
| 2015-01-31 | GLENN, GREGORY M | SVP, Research and Development | 普通株式 | 購入 | 866 | $2.28 |
| 2015-01-31 | HERRMANN, JOHN A III | SVP, General Counsel | 普通株式 | 購入 | 9,869 | $2.28 |
| 2014-12-16 | EVANS, GARY C | Director | 普通株式 | 購入 | 235,000 | $1.03 |
| 2014-12-16 | EVANS, GARY C | Director | 普通株式 | 売却 | 46,701 | $5.72 |
| 2014-12-16 | EVANS, GARY C | Director | ストックオプション | 売却 | 15,000 | $0.00 |
| 2014-12-16 | EVANS, GARY C | Director | 普通株式 | 購入 | 15,000 | $1.48 |
| 2014-12-16 | EVANS, GARY C | Director | ストックオプション | 売却 | 35,000 | $0.00 |
| 2014-12-16 | EVANS, GARY C | Director | ストックオプション | 売却 | 200,000 | $0.00 |
| 2014-12-12 | EVANS, GARY C | Director | 普通株式 | 売却 | 30,000 | $5.77 |
| 2014-11-20 | MODI, RAJIV I. | Director | 普通株式 | 売却 | 518,889 | $5.02 |
| 2014-11-18 | MODI, RAJIV I. | Director | 普通株式 | 売却 | 94,345 | $5.01 |
| 2014-11-17 | MODI, RAJIV I. | Director | 普通株式 | 売却 | 1,386,766 | $5.00 |
| 2014-10-03 | PHILLIPS, BARCLAY A | SVP, Chief Financial Officer | 普通株式 | 購入 | 5,000 | $4.11 |
| 2014-10-03 | HAHN, TIMOTHY JON | SVP, Manufacturing | 普通株式 | 購入 | 2,500 | $4.05 |
| 2014-09-26 | GLENN, GREGORY M | SVP, Research and Development | 普通株式 | 売却 | 16,109 | $4.16 |
| 2014-09-26 | GLENN, GREGORY M | SVP, Research and Development | 普通株式 | 売却 | 700 | $4.17 |
| 2014-09-25 | HAHN, TIMOTHY JON | SVP, Manufacturing | 普通株式 | 購入 | 7,016 | $4.17 |
| 2014-09-25 | HAHN, TIMOTHY JON | SVP, Manufacturing | 普通株式 | 購入 | 1,984 | $4.17 |
| 2014-07-31 | PHILLIPS, BARCLAY A | SVP, Chief Financial Officer | 普通株式 | 購入 | 8,788 | $2.28 |
| 2014-07-31 | HERRMANN, JOHN A III | SVP, General Counsel | 普通株式 | 購入 | 8,950 | $2.28 |
| 2014-07-31 | WILSON, RUSSELL P | SVP, Business Development | 普通株式 | 購入 | 4,989 | $2.28 |
| 2014-07-31 | GLENN, GREGORY M | SVP, Research and Development | 普通株式 | 購入 | 12,707 | $2.28 |
| 2014-07-31 | HAHN, TIMOTHY JON | SVP, Manufacturing & PD | 普通株式 | 購入 | 9,240 | $2.28 |
| 2014-07-31 | ERCK, STANLEY C | Director, CEO and President | 普通株式 | 購入 | 6,788 | $2.28 |
| 2014-06-17 | TRIZZINO, JOHN | SVP, Commercial Operations | 普通株式 | 購入 | 5,500 | $4.51 |
| 2014-06-17 | MCMANUS, MICHAEL A JR | Director | 普通株式 | 購入 | 15,000 | $0.56 |
| 2014-06-17 | MCMANUS, MICHAEL A JR | Director | 普通株式 | 購入 | 30,000 | $1.28 |
| 2014-06-17 | MCMANUS, MICHAEL A JR | Director | ストックオプション | 売却 | 15,000 | $0.00 |
| 2014-06-17 | MCMANUS, MICHAEL A JR | Director | ストックオプション | 売却 | 30,000 | $0.00 |
| 2014-06-16 | TRIZZINO, JOHN | SVP, Commercial Operations | 普通株式 | 購入 | 4,800 | $4.59 |
| 2014-06-16 | TRIZZINO, JOHN | SVP, Commercial Operations | 普通株式 | 購入 | 700 | $4.59 |
| 2014-06-13 | TRIZZINO, JOHN | SVP, Commercial Operations | 普通株式 | 購入 | 11,000 | $4.47 |
| 2014-06-12 | HERRMANN, JOHN A III | SVP, General Counsel | ストックオプション | 購入 | 50,000 | $0.00 |
| 2014-03-25 | DOUGLAS, RICHARD | Director | 普通株式 | 購入 | 50,000 | $4.33 |
| 2014-03-25 | PHILLIPS, BARCLAY A | SVP, Chief Financial Officer | 普通株式 | 購入 | 5,000 | $4.25 |
| 2014-03-25 | ERCK, STANLEY C | Director, CEO and President | 普通株式 | 購入 | 10,000 | $4.27 |
| 2014-03-25 | PHILLIPS, BARCLAY A | SVP, Chief Financial Officer | 普通株式 | 売却 | 5,000 | $4.25 |
| 2014-03-25 | ERCK, STANLEY C | Director, CEO and President | 普通株式 | 売却 | 10,000 | $4.27 |
| 2014-03-25 | YOUNG, JAMES F | Director | 普通株式 | 購入 | 25,000 | $4.47 |
| 2014-03-21 | MODI, RAJIV I. | Director | 普通株式 | 売却 | 1,000,000 | $4.69 |
| 2014-03-21 | CADILA, PHARMACEUTICALS LTD | 10% Owner | 普通株式 | 売却 | 1,000,000 | $4.69 |
| 2014-03-20 | MODI, RAJIV I. | Director | 普通株式 | 売却 | 1,000,000 | $4.99 |
| 2014-03-20 | CADILA, PHARMACEUTICALS LTD | 10% Owner | 普通株式 | 売却 | 1,000,000 | $4.99 |
| 2014-03-19 | MODI, RAJIV I. | Director | 普通株式 | 売却 | 1,000,000 | $5.17 |
| 2014-03-19 | CADILA, PHARMACEUTICALS LTD | 10% Owner | 普通株式 | 売却 | 1,000,000 | $5.17 |
| 2014-03-14 | GLENN, GREGORY M | SVP, Research and Development | 普通株式 | 売却 | 29,000 | $5.48 |
| 2014-03-14 | GLENN, GREGORY M | SVP, Research and Development | 普通株式 | 売却 | 2,000 | $0.00 |
| 2014-03-10 | TRIZZINO, JOHN | SVP, Commercial Operations | ストックオプション | 購入 | 300,000 | $0.00 |
| 2014-03-06 | ERCK, STANLEY C | Director, CEO and President | ストックオプション | 購入 | 900,000 | $0.00 |
| 2014-03-06 | PHILLIPS, BARCLAY A | SVP, Chief Financial Officer | ストックオプション | 購入 | 150,000 | $0.00 |
| 2014-03-06 | HAHN, TIMOTHY JON | SVP, Manufacturing & PD | ストックオプション | 購入 | 125,000 | $0.00 |
| 2014-03-06 | WILSON, RUSSELL P | SVP, Business Development | ストックオプション | 購入 | 150,000 | $0.00 |
| 2014-03-06 | GLENN, GREGORY M | SVP, Research and Development | ストックオプション | 購入 | 175,000 | $0.00 |
| 2014-03-06 | DOUGLAS, RICHARD | Director | ストックオプション | 購入 | 30,000 | $0.00 |
| 2014-03-06 | MARSH, JOHN O JR | Director | ストックオプション | 購入 | 30,000 | $0.00 |
| 2014-03-06 | YOUNG, JAMES F | Director | ストックオプション | 購入 | 75,000 | $0.00 |
| 2014-03-06 | EVANS, GARY C | Director | ストックオプション | 購入 | 30,000 | $0.00 |
| 2014-03-06 | MCMANUS, MICHAEL A JR | Director | ストックオプション | 購入 | 30,000 | $0.00 |
| 2014-01-31 | GLENN, GREGORY M | SVP, Research and Development | 普通株式 | 購入 | 4,102 | $2.29 |
| 2014-01-31 | WILSON, RUSSELL P | SVP, Business Development | 普通株式 | 購入 | 4,900 | $2.29 |
| 2014-01-31 | PHILLIPS, BARCLAY A | SVP, Chief Financial Officer | 普通株式 | 購入 | 9,868 | $2.29 |
| 2014-01-31 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 購入 | 11,868 | $2.29 |
| 2014-01-31 | HAHN, TIMOTHY JON | SVP, Manufacturing & PD | 普通株式 | 購入 | 9,416 | $2.29 |
| 2013-06-12 | PHILLIPS, BARCLAY A | SVP, Chief Financial Officer | 普通株式 | 購入 | 0 | $ |
| 2013-06-12 | DOUGLAS, RICHARD | Director | 普通株式 | 購入 | 50,000 | $1.90 |
| 2013-06-12 | PHILLIPS, BARCLAY A | Director | 普通株式 | 購入 | 50,000 | $1.90 |
| 2013-06-10 | HAHN, TIMOTHY JON | SVP, Manufacturing & PD | 普通株式 | 購入 | 21,000 | $1.88 |
| 2013-06-07 | GLENN, GREGORY M | Chief Scientific Officer | 普通株式 | 購入 | 1,000 | $1.83 |
| 2013-06-06 | GLENN, GREGORY M | Chief Scientific Officer | 普通株式 | 購入 | 1,000 | $2.01 |
| 2013-06-06 | YOUNG, JAMES F | Director | 普通株式 | 購入 | 100,000 | $1.91 |
| 2013-04-24 | EVANS, GARY C | Director | 普通株式 | 売却 | 40,000 | $2.44 |
| 2013-04-24 | EVANS, GARY C | Director | 普通株式 | 売却 | 39,000 | $2.46 |
| 2013-03-11 | YOUNG, JAMES F | Director | 普通株式 | 購入 | 100,000 | $2.03 |
| 2013-03-02 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 購入 | 900,000 | $1.83 |
| 2013-03-02 | MCMANUS, MICHAEL A JR | Director | 普通株式 | 購入 | 30,000 | $1.83 |
| 2013-03-02 | MARSH, JOHN O JR | Director | 普通株式 | 購入 | 30,000 | $1.83 |
| 2013-03-02 | HAHN, TIMOTHY JON | SVP, Manufacturing & PD | 普通株式 | 購入 | 150,000 | $1.83 |
| 2013-03-02 | GLENN, GREGORY M | Chief Scientific Officer | 普通株式 | 購入 | 150,000 | $1.83 |
| 2013-03-02 | EVANS, GARY C | Director | 普通株式 | 購入 | 30,000 | $1.83 |
| 2013-03-02 | WILSON, RUSSELL P | SVP, Business Development | 普通株式 | 購入 | 150,000 | $1.83 |
| 2013-03-02 | DRISCOLL, FREDERICK W | VP, CFO & Treasurer | 普通株式 | 購入 | 150,000 | $1.83 |
| 2013-03-02 | DOUGLAS, RICHARD | Director | 普通株式 | 購入 | 30,000 | $1.83 |
| 2013-03-02 | YOUNG, JAMES F | Director | 普通株式 | 購入 | 75,000 | $1.83 |
| 2012-05-14 | HAHN, TIMOTHY JON | SVP, Manufacturing & PD | 普通株式 | 購入 | 30,000 | $1.33 |
| 2012-05-10 | GLENN, GREGORY M | Chief Scientific Officer | 普通株式 | 購入 | 25,000 | $1.35 |
| 2012-04-10 | DOUGLAS, RICHARD | Director | 普通株式 | 購入 | 50,000 | $1.21 |
| 2012-03-01 | WILSON, RUSSELL P | SVP, Business Development | 普通株式 | 購入 | 25,000 | $1.28 |
| 2012-03-01 | DOUGLAS, RICHARD | Director | 普通株式 | 購入 | 20,000 | $1.28 |
| 2012-03-01 | EVANS, GARY C | Director | 普通株式 | 購入 | 20,000 | $1.28 |
| 2012-03-01 | MARSH, JOHN O JR | Director | 普通株式 | 購入 | 20,000 | $1.28 |
| 2012-03-01 | MCMANUS, MICHAEL A JR | Director | 普通株式 | 購入 | 20,000 | $1.28 |
| 2012-03-01 | YOUNG, JAMES F | Director | 普通株式 | 購入 | 20,000 | $1.28 |
| 2012-03-01 | DRISCOLL, FREDERICK W | VP, CFO & Treasurer | 普通株式 | 購入 | 150,000 | $1.28 |
| 2012-03-01 | GLENN, GREGORY M | Chief Scientific Officer | 普通株式 | 購入 | 150,000 | $1.28 |
| 2012-03-01 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 購入 | 900,000 | $1.28 |
| 2011-12-05 | GLENN, GREGORY M | Chief Scientific Officer | 普通株式 | 購入 | 2,000 | $1.50 |
| 2011-12-01 | YOUNG, JAMES F | Director | 普通株式 | 購入 | 200,000 | $1.46 |
| 2011-11-29 | GLENN, GREGORY M | Chief Scientific Officer | 普通株式 | 購入 | 2,000 | $1.26 |
| 2011-08-23 | EVANS, GARY C | Director | 普通株式 | 売却 | 476,576 | $1.22 |
| 2011-08-22 | EVANS, GARY C | Director | 普通株式 | 売却 | 214,800 | $1.25 |
| 2011-08-19 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 購入 | 13,000 | $1.26 |
| 2011-08-10 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 購入 | 16,552 | $1.24 |
| 2011-08-09 | DOUGLAS, RICHARD | Director | 普通株式 | 購入 | 50,000 | $1.20 |
| 2011-08-09 | DRISCOLL, FREDERICK W | VP, CFO & Treasurer | 普通株式 | 購入 | 20,000 | $1.18 |
| 2011-08-09 | TRIZZINO, JOHN | Snr. VP, Int & Govt Alliances | 普通株式 | 購入 | 10,000 | $1.20 |
| 2011-08-09 | TRIZZINO, JOHN | Snr. VP, Int & Govt Alliances | 普通株式 | 購入 | 10,000 | $1.18 |
| 2011-08-09 | ERCK, STANLEY C | Director, President and CEO | 普通株式 | 購入 | 33,448 | $1.24 |
| 2011-06-23 | EVANS, GARY C | Director | 普通株式 | 売却 | 476,576 | $1.22 |
| 2011-06-22 | ERCK, STANLEY C | Director | 普通株式 | 購入 | 850,000 | $1.99 |
| 2011-06-22 | EVANS, GARY C | Director | 普通株式 | 売却 | 214,800 | $1.25 |
| 2011-06-20 | DOUGLAS, RICHARD | Director | 普通株式 | 購入 | 50,000 | $2.04 |
| 2011-04-19 | YOUNG, JAMES F | Director | 普通株式 | 購入 | 200,000 | $0.00 |
| 2011-04-07 | GLENN, GREGORY M | Chief Scientific Officer | 普通株式 | 売却 | 52,000 | $2.56 |
| 2011-03-10 | EVANS, GARY C | Director | 普通株式 | 購入 | 20,000 | $2.50 |
| 2011-03-10 | TRIZZINO, JOHN | Snr. VP, Int & Govt Alliances | 普通株式 | 購入 | 100,000 | $2.50 |
| 2011-03-10 | DRISCOLL, FREDERICK W | VP, CFO & Treasurer | 普通株式 | 購入 | 150,000 | $2.50 |
| 2011-03-10 | GLENN, GREGORY M | Chief Scientific Officer | 普通株式 | 購入 | 64,000 | $2.50 |
| 2011-03-10 | SINGHVI, RAHUL | Director, President, CEO | 普通株式 | 購入 | 250,000 | $2.50 |
| 2011-03-10 | YOUNG, JAMES F | Director | 普通株式 | 購入 | 20,000 | $2.50 |
| 2011-03-10 | MCMANUS, MICHAEL A JR | Director | 普通株式 | 購入 | 20,000 | $2.50 |
| 2011-03-10 | MARSH, JOHN O JR | Director | 普通株式 | 購入 | 20,000 | $2.50 |
| 2011-03-10 | DOUGLAS, RICHARD | Director | 普通株式 | 購入 | 20,000 | $2.50 |
| 2010-08-25 | GLENN, GREGORY M | Chief Scientific Officer | 普通株式 | 購入 | 2,000 | $2.01 |
| 2010-04-15 | EVANS, GARY C | Director | 普通株式 | 購入 | 5,000 | $0.00 |
| 2010-04-15 | DRISCOLL, FREDERICK W | VP, CFO & Treasurer | 普通株式 | 購入 | 30,000 | $0.00 |
| 2010-04-15 | LAMBERT, JOHN A | Director | 普通株式 | 購入 | 5,000 | $0.00 |
| 2010-04-15 | MCMANUS, MICHAEL A JR | Director | 普通株式 | 購入 | 5,000 | $0.00 |
| 2010-04-15 | MARSH, JOHN O JR | Director | 普通株式 | 購入 | 5,000 | $0.00 |
| 2010-04-05 | YOUNG, JAMES F | Director | 普通株式 | 購入 | 20,000 | $0.00 |
| 2010-03-15 | DRISCOLL, FREDERICK W | VP, CFO & Treasurer | 普通株式 | 購入 | 30,000 | $0.00 |
| 2010-03-15 | JOHNSTON, THOMAS SCOTT | Vice President, Strategy | 普通株式 | 購入 | 60,000 | $0.00 |
| 2010-03-15 | LAMBERT, JOHN A | Director | 普通株式 | 購入 | 15,000 | $0.00 |
| 2010-03-15 | MARSH, JOHN O JR | Director | 普通株式 | 購入 | 15,000 | $0.00 |
| 2010-03-15 | MCMANUS, MICHAEL A JR | Director | 普通株式 | 購入 | 15,000 | $0.00 |
| 2010-03-15 | SINGHVI, RAHUL | Director, President, CEO | 普通株式 | 購入 | 150,000 | $0.00 |
| 2010-03-15 | TRIZZINO, JOHN | Snr. VP, Int & Govt Alliances | 普通株式 | 購入 | 100,000 | $0.00 |
| 2010-03-15 | EVANS, GARY C | Director | 普通株式 | 購入 | 15,000 | $0.00 |
| 2010-02-15 | ERCK, STANLEY C | Director | ストックオプション | 購入 | 300,000 | $0.00 |
| 2009-08-24 | DRISCOLL, FREDERICK W | VP, CFO & Treasurer | ストックオプション | 購入 | 220,000 | $0.00 |
| 2009-08-24 | DRISCOLL, FREDERICK W | VP, CFO & Treasurer | 普通株式 | 購入 | 10,000 | $0.00 |
| 2009-07-20 | TRIZZINO, JOHN | Snr. VP, Int & Govt Alliances | ストックオプション | 購入 | 220,000 | $0.00 |
| 2009-07-02 | HAGE, RAYMOND JOSEPH | Sr. VP. Commercial Operations | 普通株式 | 売却 | 708 | $2.89 |
| 2009-07-02 | LAMBERT, JOHN A | Director | 普通株式 | 売却 | 3,400 | $2.82 |
| 2009-07-02 | LAMBERT, JOHN A | Director | 普通株式 | 売却 | 9,146 | $2.81 |
| 2009-07-02 | LAMBERT, JOHN A | Director | 普通株式 | 売却 | 7,400 | $2.80 |
| 2009-07-02 | LAMBERT, JOHN A | Director | 普通株式 | 売却 | 1,300 | $2.77 |
| 2009-07-02 | LAMBERT, JOHN A | Director | 普通株式 | 売却 | 200 | $2.76 |
| 2009-07-02 | HAGE, RAYMOND JOSEPH | Sr. VP. Commercial Operations | 普通株式 | 購入 | 100,000 | $0.74 |
| 2009-07-02 | HAGE, RAYMOND JOSEPH | Sr. VP. Commercial Operations | 普通株式 | 売却 | 1,392 | $2.88 |
| 2009-07-02 | HAGE, RAYMOND JOSEPH | Sr. VP. Commercial Operations | 普通株式 | 売却 | 1,500 | $2.86 |
| 2009-07-02 | HAGE, RAYMOND JOSEPH | Sr. VP. Commercial Operations | 普通株式 | 売却 | 29,734 | $2.85 |
| 2009-07-02 | HAGE, RAYMOND JOSEPH | Sr. VP. Commercial Operations | 普通株式 | 売却 | 2,000 | $2.84 |
| 2009-07-02 | HAGE, RAYMOND JOSEPH | Sr. VP. Commercial Operations | 普通株式 | 売却 | 5,136 | $2.82 |
| 2009-07-02 | HAGE, RAYMOND JOSEPH | Sr. VP. Commercial Operations | 普通株式 | 売却 | 19,200 | $2.79 |
| 2009-07-02 | HAGE, RAYMOND JOSEPH | Sr. VP. Commercial Operations | 普通株式 | 売却 | 37,884 | $3.05 |
| 2009-07-02 | HAGE, RAYMOND JOSEPH | Sr. VP. Commercial Operations | 普通株式 | 売却 | 24,138 | $2.80 |
| 2009-07-02 | HAGE, RAYMOND JOSEPH | Sr. VP. Commercial Operations | ストックオプション | 購入 | 100,000 | $0.00 |
| 2009-07-02 | HEATON, PENNY | VP & Chief Medical Officer | 普通株式 | 売却 | 8,333 | $2.86 |
| 2009-07-02 | SINGHVI, RAHUL | Director, President, CEO | 普通株式 | 売却 | 50,000 | $3.00 |
| 2009-07-02 | LAMBERT, JOHN A | Director | 普通株式 | 売却 | 5,500 | $2.86 |
| 2009-07-02 | LAMBERT, JOHN A | Director | 普通株式 | 売却 | 400 | $2.85 |
| 2009-07-02 | LAMBERT, JOHN A | Director | 普通株式 | 売却 | 2,900 | $2.84 |
| 2009-07-02 | LAMBERT, JOHN A | Director | 普通株式 | 売却 | 4,500 | $2.83 |
| 2009-07-02 | HAGE, RAYMOND JOSEPH | Sr. VP. Commercial Operations | 普通株式 | 売却 | 10,300 | $2.80 |
| 2009-07-02 | HAGE, RAYMOND JOSEPH | Sr. VP. Commercial Operations | 普通株式 | 売却 | 30,030 | $2.81 |
| 2009-07-01 | SINGHVI, RAHUL | Director, President, CEO | 普通株式 | 売却 | 2,234 | $2.88 |
| 2009-07-01 | SINGHVI, RAHUL | Director, President, CEO | 普通株式 | 売却 | 22,200 | $2.90 |
| 2009-07-01 | SINGHVI, RAHUL | Director, President, CEO | 普通株式 | 売却 | 5,100 | $2.93 |
| 2009-07-01 | SINGHVI, RAHUL | Director, President, CEO | ストックオプション | 購入 | 150,000 | $0.00 |
| 2009-07-01 | SINGHVI, RAHUL | Director, President, CEO | 普通株式 | 購入 | 150,000 | $0.74 |
| 2009-07-01 | SINGHVI, RAHUL | Director, President, CEO | 普通株式 | 売却 | 4,800 | $2.94 |
| 2009-07-01 | SINGHVI, RAHUL | Director, President, CEO | 普通株式 | 売却 | 3,900 | $2.95 |
| 2009-07-01 | JOHNSTON, THOMAS SCOTT | Vice President, Strategy | 普通株式 | 売却 | 2,248 | $3.05 |
| 2009-07-01 | JOHNSTON, THOMAS SCOTT | Vice President, Strategy | 普通株式 | 売却 | 12,752 | $3.06 |
| 2009-07-01 | SINGHVI, RAHUL | Director, President, CEO | 普通株式 | 売却 | 7,300 | $2.91 |
| 2009-07-01 | SINGHVI, RAHUL | Director, President, CEO | 普通株式 | 売却 | 900 | $3.00 |
| 2009-07-01 | SINGHVI, RAHUL | Director, President, CEO | 普通株式 | 売却 | 20,200 | $3.01 |
| 2009-07-01 | SINGHVI, RAHUL | Director, President, CEO | 普通株式 | 売却 | 90,900 | $3.02 |
| 2009-07-01 | HAGE, RAYMOND JOSEPH | Sr. VP. Commercial Operations | 普通株式 | 売却 | 1,061 | $3.07 |
| 2009-07-01 | HAGE, RAYMOND JOSEPH | Sr. VP. Commercial Operations | 普通株式 | 売却 | 5,200 | $3.08 |
| 2009-07-01 | SINGHVI, RAHUL | Director, President, CEO | 普通株式 | 売却 | 35,300 | $3.03 |
| 2009-07-01 | SINGHVI, RAHUL | Director, President, CEO | 普通株式 | 売却 | 15,500 | $2.92 |
| 2009-06-24 | ERCK, STANLEY C | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2009-06-17 | KOPSIDAS, EVDOXIA E | Sr.Dir.Fin.,Prin.Acctg.Officer | 普通株式 | 購入 | 5,000 | $0.00 |
| 2009-03-05 | MCMANUS, MICHAEL A JR | Director | 普通株式 | 購入 | 15,000 | $0.00 |
| 2009-03-05 | HEATON, PENNY | VP & Chief Medical Officer | 普通株式 | 購入 | 75,000 | $0.00 |
| 2009-03-05 | TANANBAUM, JAMES B | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2009-03-05 | EVANS, GARY C | Director | 普通株式 | 購入 | 15,000 | $0.00 |
| 2009-03-05 | HAGE, RAYMOND JOSEPH | Sr. VP. Commercial Operations | 普通株式 | 購入 | 60,000 | $0.00 |
| 2009-03-05 | JOHNSTON, THOMAS SCOTT | Vice President, Strategy | 普通株式 | 購入 | 60,000 | $0.00 |
| 2009-03-05 | SINGHVI, RAHUL | Director, President, CEO | 普通株式 | 購入 | 175,000 | $0.00 |
| 2009-03-05 | LAMBERT, JOHN A | Director | 普通株式 | 購入 | 25,000 | $0.00 |
| 2009-03-05 | ROBINSON, JIM | VP, Technical & Quality Ops. | 普通株式 | 購入 | 75,000 | $0.00 |
| 2009-03-05 | MARSH, JOHN O JR | Director | 普通株式 | 購入 | 15,000 | $0.00 |
| 2009-03-05 | KOPSIDAS, EVDOXIA E | Dir.Fin.,Int.Princ.Acctg.Off. | 普通株式 | 購入 | 7,500 | $0.00 |
| 2009-03-05 | MONATH, THOMAS P | Director | 普通株式 | 購入 | 15,000 | $0.00 |
| 2008-09-19 | HAGE, RAYMOND JOSEPH | SVP, Commercial Operations | 普通株式 | 売却 | 19,600 | $3.11 |
| 2008-09-19 | HAGE, RAYMOND JOSEPH | SVP, Commercial Operations | 普通株式 | 売却 | 400 | $3.12 |
| 2008-09-18 | HAGE, RAYMOND JOSEPH | SVP, Commercial Operations | 普通株式 | 売却 | 9,700 | $2.94 |
| 2008-09-18 | HAGE, RAYMOND JOSEPH | SVP, Commercial Operations | 普通株式 | 売却 | 100 | $2.94 |
| 2008-09-18 | HAGE, RAYMOND JOSEPH | SVP, Commercial Operations | 普通株式 | 売却 | 200 | $2.93 |
| 2008-07-31 | HEATON, PENNY | Chief Medical Officer | 普通株式 | 購入 | 880 | $ |
| 2008-07-31 | HEATON, PENNY | Chief Medical Officer | 普通株式 | 購入 | 1,759 | $ |
| 2008-07-31 | STIGLIANO, LEN F | VP, CFO, Treasurer | 普通株式 | 購入 | 10,554 | $ |
| 2008-07-31 | JOHNSTON, THOMAS SCOTT | Vice President, Strategy | 普通株式 | 購入 | 500 | $ |
| 2008-07-31 | TANANBAUM, JAMES B | Director | 普通株式 | 購入 | 17,591 | $ |
| 2008-07-31 | EVANS, GARY C | Director | 普通株式 | 購入 | 33,878 | $ |
| 2008-07-31 | EVANS, GARY C | Director | 普通株式 | 購入 | 67,756 | $ |
| 2008-07-31 | MONATH, THOMAS P | Director | 普通株式 | 購入 | 7,000 | $ |
| 2008-07-31 | SINGHVI, RAHUL | Director, President, CEO | 普通株式 | 購入 | 5,277 | $ |
| 2008-07-31 | SINGHVI, RAHUL | Director, President, CEO | 普通株式 | 購入 | 10,554 | $ |
| 2008-07-31 | MCMANUS, MICHAEL A JR | Director | 普通株式 | 購入 | 8,795 | $ |
| 2008-07-31 | MCMANUS, MICHAEL A JR | Director | 普通株式 | 購入 | 17,590 | $ |
| 2008-07-31 | ROBINSON, JIM | VP, Tech. & Quality Operations | 普通株式 | 購入 | 8,795 | $ |
| 2008-07-31 | ROBINSON, JIM | VP, Tech. & Quality Operations | 普通株式 | 購入 | 17,590 | $ |
| 2008-07-31 | MONATH, THOMAS P | Director | 普通株式 | 購入 | 175,902 | $ |
| 2008-07-31 | MONATH, THOMAS P | Director | 普通株式 | 購入 | 3,500 | $ |
| 2008-07-31 | MONATH, THOMAS P | Director | 普通株式 | 購入 | 351,803 | $ |
| 2008-07-31 | JOHNSTON, THOMAS SCOTT | Vice President, Strategy | 普通株式 | 購入 | 1,000 | $ |
| 2008-07-31 | TANANBAUM, JAMES B | Director | 普通株式 | 購入 | 35,181 | $ |
| 2008-07-31 | LAMBERT, JOHN A | Director | 普通株式 | 購入 | 7,373 | $ |
| 2008-07-31 | LAMBERT, JOHN A | Director | 普通株式 | 購入 | 14,746 | $ |
| 2008-07-31 | STIGLIANO, LEN F | VP, CFO, Treasurer | 普通株式 | 購入 | 5,277 | $ |
| 2008-03-06 | EVANS, GARY C | Director | 普通株式 | 購入 | 15,000 | $0.00 |
| 2008-03-06 | TANANBAUM, JAMES B | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2008-03-06 | HEATON, PENNY | Chief Medical Officer | 普通株式 | 購入 | 75,000 | $0.00 |
| 2008-03-06 | ROBINSON, JIM | VP of Tech. & Qual. Operations | 普通株式 | 購入 | 37,500 | $0.00 |
| 2008-03-06 | STIGLIANO, LEN F | VP, CFO and Treasurer | 普通株式 | 購入 | 32,500 | $0.00 |
| 2008-03-06 | HAGE, RAYMOND JOSEPH | SVP, Commercial Operations | 普通株式 | 購入 | 60,000 | $0.00 |
| 2008-03-06 | SINGHVI, RAHUL | Director, President and CEO | 普通株式 | 購入 | 175,000 | $0.00 |
| 2008-03-06 | LAMBERT, JOHN A | Director | 普通株式 | 購入 | 25,000 | $0.00 |
| 2008-03-06 | MARSH, JOHN O JR | Director | 普通株式 | 購入 | 15,000 | $0.00 |
| 2008-03-06 | MCMANUS, MICHAEL A JR | Director | 普通株式 | 購入 | 15,000 | $0.00 |
| 2008-03-06 | MONATH, THOMAS P | Director | 普通株式 | 購入 | 15,000 | $0.00 |
| 2008-01-30 | HEATON, PENNY | Chief Medical Officer | 普通株式 | 購入 | 900 | $3.05 |
| 2008-01-30 | HEATON, PENNY | Chief Medical Officer | 普通株式 | 購入 | 1,100 | $3.05 |
| 2008-01-09 | ROBINSON, JIM | VP,Technical & Quality Oper. | 普通株式 | 購入 | 5,000 | $3.07 |
| 2007-08-28 | SINGHVI, RAHUL | Director, President, CEO | 普通株式 | 購入 | 1,100 | $3.04 |
| 2007-08-27 | HAGE, RAYMOND JOSEPH | SVP, Commercial Operations | 普通株式 | 売却 | 3,165 | $3.18 |
| 2007-08-27 | HAGE, RAYMOND JOSEPH | SVP, Commercial Operations | 普通株式 | 売却 | 700 | $3.17 |
| 2007-08-27 | HAGE, RAYMOND JOSEPH | SVP, Commercial Operations | 普通株式 | 売却 | 4,600 | $3.16 |
| 2007-08-27 | HAGE, RAYMOND JOSEPH | SVP, Commercial Operations | 普通株式 | 売却 | 2,035 | $3.15 |
| 2007-08-24 | STIGLIANO, LEN F | VP, CFO, Treasurer | 普通株式 | 購入 | 10,000 | $3.14 |
| 2007-08-23 | EVANS, GARY C | Director | 普通株式 | 購入 | 10,000 | $3.02 |
| 2007-08-22 | EVANS, GARY C | Director | 普通株式 | 購入 | 20,000 | $3.10 |
| 2007-08-21 | ROBINSON, JIM | VP,Technical & Qual. Operation | 普通株式 | 購入 | 16,869 | $3.12 |
| 2007-08-21 | ROBINSON, JIM | VP,Technical & Qual. Operation | 普通株式 | 購入 | 3,131 | $3.11 |
| 2007-07-02 | STIGLIANO, LEN F | VP, CFO and Treasurer | 普通株式 | 購入 | 225,000 | $0.00 |
| 2007-03-07 | TANANBAUM, JAMES B | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2007-03-07 | MCMANUS, MICHAEL A JR | Director | 普通株式 | 購入 | 15,000 | $0.00 |
| 2007-03-07 | ODONNELL, DENIS M | Director | 普通株式 | 購入 | 15,000 | $0.00 |
| 2007-03-07 | MARSH, JOHN O JR | Director | 普通株式 | 購入 | 15,000 | $0.00 |
| 2007-03-07 | EVANS, GARY C | Director | 普通株式 | 購入 | 100,000 | $0.00 |
| 2007-03-07 | MONATH, THOMAS P | Director | 普通株式 | 購入 | 15,000 | $0.00 |
| 2007-03-07 | SINGHVI, RAHUL | Director, President & CEO | 普通株式 | 購入 | 100,000 | $0.00 |
| 2007-03-07 | HAGE, RAYMOND JOSEPH | SVP, Commercial Operations | 普通株式 | 購入 | 75,000 | $0.00 |
| 2007-03-07 | CHURCH, JEFFREY WAYNE | VP, CFO, Treasurer & Corp. Sec | 普通株式 | 購入 | 25,000 | $0.00 |
| 2007-03-07 | LAMBERT, JOHN A | Director | 普通株式 | 購入 | 100,000 | $0.00 |
| 2007-03-07 | LAMBERT, JOHN A | Director | 普通株式 | 購入 | 250,000 | $0.00 |
| 2006-10-31 | HALL, PATRICIA | Chief Accounting Officer | 普通株式 | 購入 | 7,500 | $3.98 |
| 2006-10-31 | HALL, PATRICIA | Chief Accounting Officer | ストックオプション | 売却 | 7,500 | $3.98 |
| 2006-10-31 | HALL, PATRICIA | Chief Accounting Officer | 普通株式 | 売却 | 7,500 | $4.41 |
| 2006-10-30 | HALL, PATRICIA | Chief Accounting Officer | ストックオプション | 売却 | 3,750 | $1.48 |
| 2006-10-30 | HALL, PATRICIA | Chief Accounting Officer | 普通株式 | 購入 | 9,000 | $1.34 |
| 2006-10-30 | HALL, PATRICIA | Chief Accounting Officer | 普通株式 | 売却 | 9,000 | $4.09 |
| 2006-10-30 | HALL, PATRICIA | Chief Accounting Officer | 普通株式 | 購入 | 3,750 | $1.48 |
| 2006-10-30 | HALL, PATRICIA | Chief Accounting Officer | 普通株式 | 売却 | 3,750 | $4.09 |
| 2006-10-30 | HALL, PATRICIA | Chief Accounting Officer | ストックオプション | 売却 | 9,000 | $1.34 |
| 2006-08-22 | EVANS, GARY C | Director | 普通株式 | 購入 | 3,600 | $3.49 |
| 2006-08-22 | EVANS, GARY C | Director | 普通株式 | 購入 | 4,000 | $3.55 |
| 2006-08-22 | EVANS, GARY C | Director | 普通株式 | 購入 | 50,000 | $3.55 |
| 2006-08-22 | EVANS, GARY C | Director | 普通株式 | 購入 | 400 | $3.51 |
| 2006-04-11 | EVANS, GARY C | Director | 普通株式 | 購入 | 25,000 | $4.95 |
| 2006-03-09 | ODONNELL, DENIS M | Director | 普通株式 | 売却 | 74,155 | $5.42 |
| 2006-03-08 | ODONNELL, DENIS M | Director | 普通株式 | 売却 | 157,400 | $5.38 |
| 2006-03-03 | KELLY, MITCHELL J | Director | 普通株式 | 売却 | 800,000 | $5.38 |
| 2006-03-02 | KELLY, MITCHELL J | Director | 普通株式 | 売却 | 939,601 | $5.41 |
| 2006-02-17 | LAZARUS, J MICHAEL MD | Director | 普通株式 | 購入 | 15,000 | $4.60 |
| 2006-02-17 | ODONNELL, DENIS M | Director | 普通株式 | 購入 | 15,000 | $4.60 |
| 2006-02-17 | SINGHVI, RAHUL | Director, President, CEO | 普通株式 | 購入 | 100,000 | $4.60 |
| 2006-02-17 | SINGHVI, RAHUL | Director, President, CEO | 譲渡制限付株式ユニット | 購入 | 50,000 | $ |
| 2006-02-17 | HAGE, RAYMOND JOSEPH | Sr. VP, COO | 普通株式 | 購入 | 50,000 | $4.60 |
| 2006-02-17 | MARSH, JOHN O JR | Director | 普通株式 | 購入 | 15,000 | $4.60 |
| 2006-02-17 | MCMANUS, MICHAEL A JR | Director | 普通株式 | 購入 | 15,000 | $4.60 |
| 2006-02-17 | EVANS, GARY C | Director | 普通株式 | 購入 | 50,000 | $4.60 |
| 2006-02-17 | KELLY, MITCHELL J | Director | 普通株式 | 購入 | 15,000 | $4.60 |
| 2006-02-17 | GENGE, DENNIS W | VP, Treasurer,CFO | 譲渡制限付株式ユニット | 購入 | 25,000 | $ |
| 2006-01-25 | EVANS, GARY C | Director | 普通株式 | 購入 | 50,000 | $4.00 |
| 2005-12-15 | LAZARUS, J MICHAEL MD | Director | 普通株式 | 購入 | 10,000 | $3.75 |
| 2005-12-15 | LAZARUS, J MICHAEL MD | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2005-12-15 | LAZARUS, J MICHAEL MD | Director | 普通株式 | 売却 | 10,000 | $4.40 |
| 2005-12-08 | EVANS, GARY C | Director | 普通株式 | 購入 | 50,000 | $3.50 |
| 2005-12-07 | EVANS, GARY C | Director | 普通株式 | 購入 | 50,000 | $3.60 |
| 2005-11-14 | EVANS, GARY C | Director | 普通株式 | 購入 | 40,000 | $2.89 |
| 2005-11-11 | EVANS, GARY C | Director | 普通株式 | 購入 | 5,000 | $3.12 |
| 2005-09-12 | EVANS, GARY C | Director | 普通株式 | 購入 | 15,000 | $1.55 |
| 2005-09-12 | EVANS, GARY C | Director | 普通株式 | 購入 | 26,000 | $1.50 |
| 2005-09-09 | KELLY, MITCHELL J | Director | 普通株式 | 売却 | 260,000 | $1.57 |
| 2005-09-06 | EVANS, GARY C | Director | 普通株式 | 購入 | 44,000 | $1.29 |
| 2005-09-02 | SJ, STRATEGIC INVESTMENTS LLC | 10% Owner | 普通株式 | 売却 | 608,639 | $1.41 |
| 2005-09-01 | MCMANUS, MICHAEL A JR | Director | 普通株式 | 購入 | 20,000 | $1.60 |
| 2005-09-01 | SJ, STRATEGIC INVESTMENTS LLC | 10% Owner | 普通株式 | 売却 | 557,200 | $1.56 |
| 2005-08-31 | SJ, STRATEGIC INVESTMENTS LLC | 10% Owner | 普通株式 | 売却 | 605,000 | $1.60 |
| 2005-08-26 | HAGE, RAYMOND JOSEPH | Sr. VP, COO | 普通株式 | 購入 | 54,000 | $1.34 |
| 2005-08-26 | HAGE, RAYMOND JOSEPH | Sr. VP, COO | 普通株式 | 購入 | 60,000 | $1.34 |
| 2005-08-26 | SINGHVI, RAHUL | Director, President, CEO | 普通株式 | 購入 | 200,000 | $1.34 |
| 2005-08-26 | SINGHVI, RAHUL | Director, President, CEO | 普通株式 | 購入 | 300,000 | $1.34 |
| 2005-08-26 | HAGE, RAYMOND JOSEPH | Sr. VP, COO | 普通株式 | 購入 | 36,000 | $1.34 |
| 2005-08-26 | HAGE, RAYMOND JOSEPH | Sr. VP, COO | 普通株式 | 購入 | 40,000 | $1.34 |
| 2005-08-24 | EVANS, GARY C | Director | 普通株式 | 購入 | 100,000 | $0.94 |
| 2005-08-23 | EVANS, GARY C | Director | 普通株式 | 購入 | 50,000 | $0.98 |
| 2005-08-22 | MARSH, JOHN O JR | Director | 普通株式 | 購入 | 5,000 | $0.98 |
| 2005-08-22 | EVANS, GARY C | Director | 普通株式 | 購入 | 50,000 | $0.97 |
| 2005-08-15 | SIMS, NELSON M | Former President & CEO | 普通株式 | 売却 | 900,000 | $5.63 |
| 2005-08-15 | SIMS, NELSON M | Former President & CEO | 普通株式 | 売却 | 135,000 | $5.95 |
| 2005-08-15 | SIMS, NELSON M | Former President & CEO | 普通株式 | 売却 | 142,000 | $2.21 |
| 2005-08-15 | SIMS, NELSON M | Former President & CEO | 普通株式 | 購入 | 250,000 | $0.87 |
| 2005-08-15 | EVANS, GARY C | Director | 普通株式 | 購入 | 50,000 | $0.88 |
| 2005-08-12 | EVANS, GARY C | Director | 普通株式 | 購入 | 50,000 | $0.94 |
| 2005-08-10 | SINGHVI, RAHUL | Director, President, CEO | 普通株式 | 購入 | 125,000 | $ |
| 2005-08-10 | ODONNELL, DENIS M | Director | 普通株式 | 購入 | 50,000 | $ |
| 2005-08-10 | HAGE, RAYMOND JOSEPH | Sr. VP, COO | 普通株式 | 購入 | 75,000 | $ |
| 2005-08-10 | SINGHVI, RAHUL | Director, President, CEO | 普通株式 | 購入 | 150,000 | $0.74 |
| 2005-08-10 | HAGE, RAYMOND JOSEPH | Sr. VP, COO | 普通株式 | 購入 | 100,000 | $0.74 |
| 2005-08-05 | SJ, STRATEGIC INVESTMENTS LLC | 10% Owner | 普通株式 | 売却 | 605,000 | $1.60 |
| 2005-07-20 | EVANS, GARY C | Director | 普通株式 | 購入 | 50,000 | $ |
| 2005-07-20 | EVANS, GARY C | Director | 普通株式 | 購入 | 125,000 | $1.03 |
| 2005-07-20 | EVANS, GARY C | Director | 普通株式 | 購入 | 150,000 | $1.03 |
| 2005-07-20 | EVANS, GARY C | Director | 普通株式 | 購入 | 35,000 | $1.03 |
| 2005-05-04 | HAGE, RAYMOND JOSEPH | VP - Business Development | 普通株式 | 購入 | 25,000 | $1.48 |
| 2005-05-04 | ODONNELL, DENIS M | Director | 普通株式 | 購入 | 15,000 | $1.48 |
| 2005-05-04 | MCMANUS, MICHAEL A JR | Director | 普通株式 | 購入 | 15,000 | $1.48 |
| 2005-05-04 | MARSH, JOHN O JR | Director | 普通株式 | 購入 | 15,000 | $1.48 |
| 2005-05-04 | LAZARUS, J MICHAEL MD | Director | 普通株式 | 購入 | 15,000 | $1.48 |
| 2005-05-04 | EVANS, GARY C | Director | 普通株式 | 購入 | 15,000 | $1.48 |
| 2005-05-04 | BAYH, SUSAN B | Director | 普通株式 | 購入 | 15,000 | $1.48 |
| 2005-05-04 | GENGE, DENNIS W | VP, Treasurer,CFO | 普通株式 | 購入 | 33,784 | $1.48 |
| 2005-05-04 | GENGE, DENNIS W | VP, Treasurer,CFO | 普通株式 | 購入 | 25,000 | $1.48 |
| 2005-05-04 | SINGHVI, RAHUL | Sr VP, COO | 普通株式 | 購入 | 33,784 | $1.48 |
| 2005-05-04 | SINGHVI, RAHUL | Sr VP, COO | 普通株式 | 購入 | 30,000 | $1.48 |
| 2005-05-04 | KELLY, MITCHELL J | Director | 普通株式 | 購入 | 15,000 | $1.48 |
| 2005-05-04 | HAGE, RAYMOND JOSEPH | VP - Business Development | 普通株式 | 購入 | 33,784 | $1.48 |
| 2005-03-11 | GENGE, DENNIS W | VP, Treasurer,CFO | 普通株式 | 購入 | 10,000 | $2.14 |
| 2005-02-24 | SIMS, NELSON M | President/CEO | 普通株式 | 購入 | 142,000 | $2.21 |
| 2005-02-24 | GENGE, DENNIS W | VP, Treasurer,CFO | 普通株式 | 購入 | 25,000 | $2.21 |
| 2004-12-30 | KELLY, MITCHELL J | Director | 普通株式 | 売却 | 25,500 | $3.26 |
| 2004-12-29 | KELLY, MITCHELL J | Director | 普通株式 | 売却 | 1,000 | $3.24 |
| 2004-12-28 | KELLY, MITCHELL J | Director | 普通株式 | 売却 | 33,500 | $3.28 |
| 2004-12-21 | KELLY, MITCHELL J | Director | 普通株式 | 売却 | 7,861 | $3.31 |
| 2004-12-21 | KELLY, MITCHELL J | Director | 普通株式 | 売却 | 19,139 | $3.31 |
| 2004-12-20 | KELLY, MITCHELL J | Director | 普通株式 | 売却 | 13,000 | $3.32 |
| 2004-10-08 | SIMS, NELSON M | President/CEO | 普通株式 | 購入 | 11,500 | $3.28 |
| 2004-09-27 | EVANS, GARY C | Director | 普通株式 | 購入 | 10,000 | $3.14 |
| 2004-09-13 | EVANS, GARY C | Director | 普通株式 | 購入 | 8,697 | $3.54 |
| 2004-09-10 | EVANS, GARY C | Director | 普通株式 | 購入 | 1,603 | $3.24 |
売上・収益性
売上高（直近12ヶ月）
$112,347万ドル
一株あたり売上高（直近12ヶ月）
$6.93
売上総利益（直近12ヶ月）
$71,361万ドル
営業利益（EBITDA：減価償却前）
$59,085万ドル
利益率
39.2%
営業利益率（直近12ヶ月）
14.2%
配当・収入
配当金額（1株あたり）
$None
配当利回り
0%
支払日
2019-05-10
権利落ち日
None
バリュエーション指標
株価収益率（PER）
3.116倍
実績PER
3.116倍
予想PER
2.585倍
株価収益成長率（PEG）
1.322
株価売上高倍率（直近12ヶ月）
1.177倍
株価純資産倍率 (PBR)
33.2倍
1株当たり純資産（BPS）
-$0.79
企業価値倍率（EV）
EV/売上高倍率
0.727倍
EV/EBITDA倍率
1.659倍
投資リターン
総資産利益率（直近12ヶ月）
25.7%
自己資本利益率（直近12ヶ月）
-898.0%
リターン分析
| 日数 | リターンレンジ | リターン中央値 | 累積リターン | 分散（バリアンス） | 標準偏差 | 最大下落率 | 最大下落期間 | SPYとの相関係数 | ||
|---|---|---|---|---|---|---|---|---|---|---|
| 15日間 | -3.5503% | 2.3148% | -0.5754% | -8.8032% | 0.0002485142620625475 | 0.015764335129099086 | -7.8054% | 6日 | -0.33254457114057145 | |
| 30日間 | -4.918% | 5.5138% | -0.4711% | -2.6413% | 0.0006968078525262916 | 0.02639711826177796 | -7.8054% | 6日 | 0.016616985067258668 | |
| 90日間 | -9.3834% | 17.4187% | -0.1232% | -8.8032% | 0.0016554643959577084 | 0.04068739849090512 | -15.1921% | 5日 | -0.16646353665935962 |
損益計算書
会計期末日
2025-12-31
報告通貨
USD
売上高・粗利益
売上原価
営業経費
営業利益・税引前指標
売上高
$1,123,479,000
粗利益
$1,052,339,000
売上コスト
$71,140,000
商品・サービス原価
$71,140,000
販売管理費
$157,479,000
研究開発
$336,820,000
運営コスト
$489,068,000
減価償却
$None
減価償却・償却費
$27,613,000
営業利益
$563,271,000
営業利益EBIT
$464,714,000
償却前営業利益EBITA
$492,327,000
税引前利益
$442,167,000
利息・投資・その他営業外項目
税金関連
当期純・包括利益
純投資収益
$None
純金利収入
-$22,547,000
利息収入
$None
金利コスト
$22,547,000
利息・債務コスト
$None
非利息収益
$None
営業外収益（その他）
$None
法人税等
$1,865,000
継続事業純利益
$440,302,000
純利益
$440,302,000
税引後包括利益
$None
貸借対照表
会計期末日
2025-12-31
報告通貨
USD
総資産
$1,176,512,000
現金及び現金同等物
$240,634,000
現金及び短期投資
$240,634,000
短期投資
$494,450,000
在庫資産
$11,545,000
流動売掛金（純額）
$106,446,000
その他流動資産
$125,201,000
流動資産合計
$978,276,000
有形固定資産
$None
減価償却累計額（PPE）
$None
無形資産
$None
無形資産（のれん除く）
$None
のれん（無形資産）
$113,462,000
投資
$None
長期投資
$None
その他固定資産
$None
固定資産合計
$198,236,000
総負債
$1,304,265,000
買掛金（短期）
$24,578,000
前受金
$None
流動債務
$None
短期借入金
$2,507,000
固定長期負債
$None
その他流動負債
$292,812,000
流動負債合計
$459,950,000
リース債務
$4,598,000
長期債務
$244,213,000
長期債務（流動外）
$None
短期・長期借入金合計
$248,811,000
その他固定負債
$239,068,000
固定負債合計
$844,315,000
純資産
-$127,753,000
自己株式（金庫株）
$None
利益剰余金
-$4,568,148,000
普通株式
$1,650,000
発行済株式数（普通株）
$173,103,000
キャッシュフロー計算書
会計期末日
2025-12-31
報告通貨
USD
損益計算・収益性
営業活動
投資活動
損益
$None
純利益
$440,302,000
営業キャッシュフロー
-$244,635,000
営業活動による支払い
$None
営業活動によるキャッシュフロー
$None
営業活動に関連する負債の増減額
$None
営業活動に関連する資産の増減額
$None
売掛金の増減額
$None
在庫資産の増減額
-$3,240,000
減価償却・減耗費・償却費
$27,613,000
投資活動によるキャッシュフロー
-$78,267,000
設備投資
$5,560,000
財務活動
資金・為替照合
財務活動によるキャッシュフロー
$27,737,000
短期融資回収金
$None
自社株買い支出（普通株）
$None
自社株買い支出（優先株）
$None
自社株買い支出
$None
配当支払い（普通株）
$None
配当支払い（優先株）
$None
配当支払い
$None
資金調達（普通株）
$None
資金調達（優先株）
$None
資金調達（長期債・資本証券）
$None
自社株売却による収益
$None
自社株再取得による収益
-$4,798,000
現金及び現金同等物の増減額
$None
為替レートの変動による増減額
$None
発行済株式数
広告パネル
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