PCRX
パサイラ・バイオサイエンシズ
Pacira BioSciences, Inc.
株価・概要
$25.49
0.35 (1.3922%)
06:00AM 2026/05/01 (JST)
NASDAQ | USD
52週間レンジ
18.8
27.64
昨夜レンジ
25.03
26.27
前日終値
$25.14
出来高（数量）
1,086,622
ベータ値
0.195
50日移動平均値
$23.07
200日移動平均値
$23.58
1株あたりの利益（EPS）
0.16
予想PER（株価収益率）
10.44
配当金
$None
配当利回り
0%
インサイダー保有率
3.323%
機関投資家保有率
119.387%
PCRX - 会社概要
Pacira BioSciences, Inc.（PCRX）は、ニュージャージー州パーシッパニーに本社を置く先駆的なバイオ医薬品企業であり、革新的な非オピオイド治療法と再生医療ソリューションを通じて疼痛管理の変革に取り組んでいます。Paciraは高度な疼痛管理の代替手段に注力することで、オピオイド依存を減らし、患者の転帰を向上させ、医療従事者の実践を支援する効果的なソリューションの重要なニーズに応えています。強力なパイプラインと研究開発への強いコミットメントを持つ同社は、疼痛管理の進化をリードする戦略的な立場にあり、患者ケアおよびより広範な医療エコシステムに大きく貢献しています。
本社住所
2000 SIERRA POINT PARKWAY, BRISBANE, CA, UNITED STATES, 94005
企業サイト
https://www.pacira.com
会計年度終了
December
最新四半期
2025-12-31
利益・成長性
1株あたりの利益（EPS）
$0.16
希薄化後1株当たり利益EPS（直近12ヶ月）
$0.16
四半期利益成長率（前年比）
-88.4%
四半期売上成長率（前年比）
5.1%
アナリスト予想・評価
目標株価
$28.71
強気
1
買い
3
ホールド
2
売り
0
弱気
1
EPS（1株当たり純利益）
| 7日前 | 30日前 | 60日前 | 90日前 | 予想レンジ | |||
|---|---|---|---|---|---|---|---|
配当履歴
| 権利落ち日 | 配当宣言日 | 権利確定日 | 配当金支払日 | 配当金額 |
|---|
株式分割
| 効力発生日 | 分割比率 |
|---|
インサイダーの売却・購入履歴
| 自社株取引日 | 役員・従業員名 | 役員・従業員の役職 | 株式の種類 | 売却／購入 | 株数 | 株価 |
|---|---|---|---|---|---|---|
| 2026-03-17 | FROIMSON, MARK | Director | 普通株式 | 売却 | 500 | $21.81 |
| 2026-03-17 | SLONIN, JONATHAN | Chief Medical Officer | 普通株式 | 売却 | 3,261 | $22.82 |
| 2026-02-11 | SLONIN, JONATHAN | Chief Medical Officer | 普通株式 | 購入 | 54,546 | $0.00 |
| 2026-02-11 | CROSS, SHAWN | Chief Financial Officer | 普通株式 | 購入 | 49,091 | $0.00 |
| 2026-02-11 | WILLIAMS, KRISTEN | Chief Administrative Officer | 普通株式 | 購入 | 54,546 | $0.00 |
| 2026-02-11 | TEEHAN, BRENDAN | Chief Commercial Officer | 普通株式 | 購入 | 51,714 | $0.00 |
| 2026-02-11 | RIKER, LAUREN | Senior Vice President, Finance | 普通株式 | 購入 | 19,273 | $0.00 |
| 2026-02-11 | LEE, FRANK D. | Director, Chief Executive Officer | 普通株式 | 購入 | 261,818 | $0.00 |
| 2026-02-02 | WILLIAMS, KRISTEN | Chief Administrative Officer | 普通株式 | 売却 | 13,137 | $20.53 |
| 2026-02-02 | RIKER, LAUREN | Senior Vice President, Finance | 普通株式 | 売却 | 4,000 | $20.81 |
| 2026-01-30 | TEEHAN, BRENDAN | Chief Commercial Officer | 普通株式 | 売却 | 5,182 | $20.54 |
| 2026-01-30 | LEE, FRANK D. | Director, Chief Executive Officer | 普通株式 | 売却 | 41,488 | $20.54 |
| 2026-01-30 | RIKER, LAUREN | Senior Vice President, Finance | 普通株式 | 売却 | 2,751 | $20.54 |
| 2026-01-30 | WILLIAMS, KRISTEN | Chief Administrative Officer | 普通株式 | 売却 | 17,134 | $20.54 |
| 2026-01-30 | SLONIN, JONATHAN | Chief Medical Officer | 普通株式 | 売却 | 6,168 | $20.54 |
| 2026-01-27 | HIRAWAT, SAMIT | Director | ストックオプション | 購入 | 39,291 | $0.00 |
| 2026-01-05 | RIKER, LAUREN | Senior Vice President, Finance | 普通株式 | 売却 | 1,416 | $24.24 |
| 2026-01-05 | RIKER, LAUREN | Senior Vice President, Finance | 普通株式 | 売却 | 1,416 | $24.24 |
| 2026-01-02 | LEE, FRANK D. | Director, Chief Executive Officer | 普通株式 | 売却 | 9,272 | $24.46 |
| 2026-01-02 | RIKER, LAUREN | Senior Vice President, Finance | 普通株式 | 売却 | 159 | $24.46 |
| 2026-01-02 | RIKER, LAUREN | Senior Vice President, Finance | 普通株式 | 売却 | 159 | $24.46 |
| 2026-01-02 | LEE, FRANK D. | Director, Chief Executive Officer | 普通株式 | 売却 | 9,272 | $24.46 |
| 2026-01-02 | SLONIN, JONATHAN | Chief Medical Officer | 普通株式 | 売却 | 381 | $24.46 |
| 2026-01-02 | SLONIN, JONATHAN | Chief Medical Officer | 普通株式 | 売却 | 381 | $24.46 |
| 2025-12-31 | TEEHAN, BRENDAN | Chief Commercial Officer | 普通株式 | 購入 | 402.268 | $10.76 |
| 2025-12-31 | TEEHAN, BRENDAN | Chief Commercial Officer | 普通株式 | 購入 | 402.268 | $10.76 |
| 2025-12-10 | CROSS, SHAWN | Chief Financial Officer | 普通株式 | 売却 | 9,104 | $25.14 |
| 2025-12-10 | CROSS, SHAWN | Chief Financial Officer | ストックオプション | 売却 | 9,104 | $0.00 |
| 2025-12-10 | CROSS, SHAWN | Chief Financial Officer | 普通株式 | 購入 | 9,104 | $16.45 |
| 2025-12-09 | CROSS, SHAWN | Chief Financial Officer | 普通株式 | 購入 | 15,896 | $16.45 |
| 2025-12-09 | CROSS, SHAWN | Chief Financial Officer | 普通株式 | 売却 | 15,896 | $25.03 |
| 2025-12-09 | CROSS, SHAWN | Chief Financial Officer | ストックオプション | 売却 | 15,896 | $0.00 |
| 2025-11-17 | SLONIN, JONATHAN | Chief Medical Officer | 普通株式 | 売却 | 3,960 | $24.09 |
| 2025-11-10 | CROSS, SHAWN | Chief Financial Officer | 普通株式 | 売却 | 12,060 | $22.09 |
| 2025-10-31 | CROSS, SHAWN | Chief Financial Officer | 普通株式 | 売却 | 6,690 | $21.38 |
| 2025-09-04 | CEESAY, ABRAHAM | Director | 普通株式 | 売却 | 2,354 | $27.19 |
| 2025-08-07 | BIGAL, MARCELO | Director | 普通株式 | 売却 | 4,912 | $23.67 |
| 2025-08-01 | SLONIN, JONATHAN | Chief Medical Officer | 普通株式 | 売却 | 315 | $22.07 |
| 2025-06-11 | YANG, MICHAEL J. | Director | 普通株式 | 購入 | 6,163 | $0.00 |
| 2025-06-11 | FROIMSON, MARK | Director | ストックオプション | 購入 | 11,279 | $0.00 |
| 2025-06-11 | FROIMSON, MARK | Director | 普通株式 | 購入 | 6,163 | $0.00 |
| 2025-06-11 | CEESAY, ABRAHAM | Director | 普通株式 | 購入 | 6,163 | $0.00 |
| 2025-06-11 | KRONENFELD, MARK A. | Director | ストックオプション | 購入 | 11,279 | $0.00 |
| 2025-06-11 | KRONENFELD, MARK A. | Director | 普通株式 | 購入 | 9,999 | $0.00 |
| 2025-06-11 | BREGE, LAURA | Director | ストックオプション | 購入 | 11,279 | $0.00 |
| 2025-06-11 | CHRISTIE, CHRISTOPHER | Director | ストックオプション | 購入 | 11,279 | $0.00 |
| 2025-06-11 | KRONENFELD, MARK A. | Director | 普通株式 | 購入 | 6,163 | $0.00 |
| 2025-06-11 | BIGAL, MARCELO | Director | 普通株式 | 購入 | 6,163 | $0.00 |
| 2025-06-11 | BIGAL, MARCELO | Director | ストックオプション | 購入 | 11,279 | $0.00 |
| 2025-06-11 | YANG, MICHAEL J. | Director | ストックオプション | 購入 | 11,279 | $0.00 |
| 2025-06-11 | CHRISTIE, CHRISTOPHER | Director | 普通株式 | 購入 | 6,163 | $0.00 |
| 2025-06-11 | CEESAY, ABRAHAM | Director | ストックオプション | 購入 | 11,279 | $0.00 |
| 2025-06-11 | YOUNG, ALETHIA | Director | 普通株式 | 購入 | 6,163 | $0.00 |
| 2025-06-11 | BREGE, LAURA | Director | 普通株式 | 購入 | 6,163 | $0.00 |
| 2025-06-11 | YOUNG, ALETHIA | Director | ストックオプション | 購入 | 11,279 | $0.00 |
| 2025-06-04 | RIKER, LAUREN | Senior Vice President, Finance | 普通株式 | 売却 | 5,578.335 | $26.21 |
| 2025-06-04 | WILLIAMS, KRISTEN | Chief Administrative Officer | 普通株式 | 売却 | 14,376 | $26.24 |
| 2025-06-03 | RIKER, LAUREN | Senior Vice President, Finance | 普通株式 | 売却 | 3,374 | $26.40 |
| 2025-06-03 | WILLIAMS, KRISTEN | Chief Administrative Officer | 普通株式 | 売却 | 6,162 | $26.40 |
| 2025-06-03 | SLONIN, JONATHAN | Chief Medical Officer | 普通株式 | 売却 | 5,084 | $26.40 |
| 2025-02-04 | TEEHAN, BRENDAN | Chief Commercial Officer | ストックオプション | 購入 | 99,500 | $26.59 |
| 2025-02-01 | LEE, FRANK D. | Director, Chief Executive Officer | 普通株式 | 購入 | 350,000 | $0.00 |
| 2025-02-01 | WILLIAMS, KRISTEN | Chief Administrative Officer | 普通株式 | 購入 | 79,200 | $0.00 |
| 2025-02-01 | SLONIN, JONATHAN | Chief Medical Officer | 普通株式 | 購入 | 93,600 | $0.00 |
| 2025-02-01 | RIKER, LAUREN | Senior Vice President, Finance | 普通株式 | 購入 | 30,600 | $0.00 |
| 2025-02-01 | TEEHAN, BRENDAN | Chief Commercial Officer | 普通株式 | 購入 | 54,000 | $0.00 |
| 2025-01-06 | SLONIN, JONATHAN | Chief Medical Officer | 普通株式 | 売却 | 879 | $18.40 |
| 2025-01-02 | RIKER, LAUREN | Senior Vice President, Finance | 普通株式 | 売却 | 159 | $18.33 |
| 2025-01-02 | SLONIN, JONATHAN | Chief Medical Officer | 普通株式 | 売却 | 371 | $18.33 |
| 2025-01-02 | LEE, FRANK D. | Director, Chief Executive Officer | 普通株式 | 売却 | 9,375 | $18.33 |
| 2024-12-31 | GAUGLER, DARYL | Chief Operating Officer | 普通株式 | 購入 | 243.537 | $16.01 |
| 2024-12-13 | GAUGLER, DARYL | Chief Operating Officer | 普通株式 | 売却 | 500 | $19.76 |
| 2024-11-04 | CROSS, SHAWN | Chief Financial Officer | ストックオプション | 購入 | 200,000 | $0.00 |
| 2024-11-01 | CROSS, SHAWN | Chief Financial Officer | 普通株式 | 購入 | 75,000 | $0.00 |
| 2024-09-13 | GAUGLER, DARYL | Chief Operating Officer | 普通株式 | 売却 | 500 | $12.86 |
| 2024-08-16 | BIGAL, MARCELO | Director | 普通株式 | 購入 | 1,512 | $13.25 |
| 2024-08-16 | BREGE, LAURA | Director | 普通株式 | 購入 | 1,000 | $12.81 |
| 2024-08-14 | YANG, MICHAEL J. | Director | 普通株式 | 購入 | 2,000 | $12.90 |
| 2024-08-12 | FROIMSON, MARK | Director | 普通株式 | 購入 | 1,400 | $11.58 |
| 2024-08-12 | LEE, FRANK D. | Director, Chief Executive Officer | 普通株式 | 購入 | 8,264 | $12.10 |
| 2024-08-12 | BIGAL, MARCELO | Director | 普通株式 | 購入 | 3,400 | $12.01 |
| 2024-08-02 | SLONIN, JONATHAN | Chief Medical Officer | 普通株式 | 売却 | 945 | $20.05 |
| 2024-08-01 | SLONIN, JONATHAN | Chief Medical Officer | 普通株式 | 売却 | 305 | $20.75 |
| 2024-07-02 | SLONIN, JONATHAN | Chief Medical Officer | 普通株式 | 売却 | 2,836 | $28.25 |
| 2024-07-01 | SLONIN, JONATHAN | Chief Medical Officer | 普通株式 | 売却 | 914 | $28.46 |
| 2024-06-28 | GAUGLER, DARYL | Chief Operating Officer | 普通株式 | 購入 | 160.368 | $24.32 |
| 2024-06-28 | SLONIN, JONATHAN | Chief Medical Officer | 普通株式 | 購入 | 437.271 | $24.32 |
| 2024-06-13 | GAUGLER, DARYL | Chief Operating Officer | 普通株式 | 売却 | 1,000 | $28.38 |
| 2024-06-13 | HASTINGS, PAUL J | Director | 普通株式 | 売却 | 880 | $28.38 |
| 2024-06-13 | WILLIAMS, KRISTEN | Chief Administrative Officer | 普通株式 | 売却 | 7,452 | $28.38 |
| 2024-06-12 | FROIMSON, MARK | Director | 普通株式 | 購入 | 5,230 | $0.00 |
| 2024-06-12 | RIKER, LAUREN | Senior Vice President, Finance | 普通株式 | 売却 | 3,970 | $28.72 |
| 2024-06-12 | SLONIN, JONATHAN | Chief Medical Officer | 普通株式 | 購入 | 54,300 | $0.00 |
| 2024-06-12 | CHRISTIE, CHRISTOPHER | Director | 普通株式 | 購入 | 5,230 | $0.00 |
| 2024-06-12 | CHRISTIE, CHRISTOPHER | Director | ストックオプション | 購入 | 12,179 | $0.00 |
| 2024-06-12 | BIGAL, MARCELO | Director | 普通株式 | 購入 | 5,230 | $0.00 |
| 2024-06-12 | BIGAL, MARCELO | Director | ストックオプション | 購入 | 12,179 | $0.00 |
| 2024-06-12 | REINHART, CHARLES A. III | Chief Financial Officer | 普通株式 | 購入 | 12,220 | $0.00 |
| 2024-06-12 | YANG, MICHAEL J. | Director | 普通株式 | 購入 | 5,230 | $0.00 |
| 2024-06-12 | YANG, MICHAEL J. | Director | ストックオプション | 購入 | 12,179 | $0.00 |
| 2024-06-12 | CEESAY, ABRAHAM | Director | 普通株式 | 購入 | 5,230 | $0.00 |
| 2024-06-12 | BREGE, LAURA | Director | 普通株式 | 購入 | 5,230 | $0.00 |
| 2024-06-12 | BREGE, LAURA | Director | ストックオプション | 購入 | 12,179 | $0.00 |
| 2024-06-12 | KRONENFELD, MARK A. | Director | 普通株式 | 購入 | 5,230 | $0.00 |
| 2024-06-12 | KRONENFELD, MARK A. | Director | ストックオプション | 購入 | 12,179 | $0.00 |
| 2024-06-12 | WILLIAMS, KRISTEN | Chief Administrative Officer | 普通株式 | 購入 | 54,300 | $0.00 |
| 2024-06-12 | HASTINGS, PAUL J | Director | ストックオプション | 購入 | 12,179 | $0.00 |
| 2024-06-12 | HASTINGS, PAUL J | Director | 普通株式 | 購入 | 5,230 | $0.00 |
| 2024-06-12 | YOUNG, ALETHIA | Director | ストックオプション | 購入 | 12,179 | $0.00 |
| 2024-06-12 | YOUNG, ALETHIA | Director | 普通株式 | 購入 | 5,230 | $0.00 |
| 2024-06-12 | FROIMSON, MARK | Director | ストックオプション | 購入 | 12,179 | $0.00 |
| 2024-06-12 | GAUGLER, DARYL | Chief Operating Officer | 普通株式 | 購入 | 54,300 | $0.00 |
| 2024-06-12 | CEESAY, ABRAHAM | Director | ストックオプション | 購入 | 12,179 | $0.00 |
| 2024-06-12 | RIKER, LAUREN | Senior Vice President, Finance | 普通株式 | 購入 | 21,360 | $0.00 |
| 2024-06-11 | SLONIN, JONATHAN | Chief Medical Officer | 普通株式 | 売却 | 5,012 | $28.57 |
| 2024-06-03 | GAUGLER, DARYL | Chief Operating Officer | 普通株式 | 売却 | 2,754 | $30.89 |
| 2024-06-03 | WILLIAMS, KRISTEN | Chief Administrative Officer | 普通株式 | 売却 | 3,011 | $30.89 |
| 2024-06-03 | REINHART, CHARLES A. III | Chief Financial Officer | 普通株式 | 売却 | 2,979 | $30.89 |
| 2024-06-03 | RIKER, LAUREN | Senior Vice President, Finance | 普通株式 | 売却 | 1,843 | $30.89 |
| 2024-06-03 | SLONIN, JONATHAN | Chief Medical Officer | 普通株式 | 売却 | 1,615 | $30.89 |
| 2024-03-08 | PACE, GARY W | Director | 普通株式 | 売却 | 90,000 | $30.60 |
| 2024-03-07 | PACE, GARY W | Director | 普通株式 | 売却 | 28,257 | $30.81 |
| 2024-03-06 | PACE, GARY W | Director | 普通株式 | 売却 | 1,066 | $29.67 |
| 2024-02-05 | WILLIAMS, KRISTEN | Chief Administrative Officer | 普通株式 | 購入 | 33,700 | $0.00 |
| 2024-02-05 | GAUGLER, DARYL | Chief Operating Officer | 普通株式 | 購入 | 33,700 | $0.00 |
| 2024-01-03 | LEE, FRANK D. | Director, Chief Executive Officer | ストックオプション | 購入 | 692,512 | $0.00 |
| 2024-01-03 | SLONIN, JONATHAN | Chief Medical Officer | ストックオプション | 購入 | 10,000 | $0.00 |
| 2024-01-02 | SLONIN, JONATHAN | Chief Medical Officer | 普通株式 | 購入 | 5,000 | $0.00 |
| 2024-01-02 | LEE, FRANK D. | Director, Chief Executive Officer | 普通株式 | 購入 | 99,520 | $0.00 |
| 2024-01-02 | RIKER, LAUREN | Senior Vice President, Finance | 普通株式 | 売却 | 159 | $32.00 |
| 2023-10-06 | BIGAL, MARCELO | Director | ストックオプション | 購入 | 30,967 | $0.00 |
| 2023-10-06 | YANG, MICHAEL J. | Director | ストックオプション | 購入 | 30,967 | $0.00 |
| 2023-10-06 | YOUNG, ALETHIA | Director | ストックオプション | 購入 | 30,967 | $0.00 |
| 2023-10-06 | CEESAY, ABRAHAM | Director | ストックオプション | 購入 | 30,967 | $0.00 |
| 2023-08-02 | WINSTON, ROY | Chief Medical Officer | 普通株式 | 売却 | 509 | $34.88 |
| 2023-07-05 | RIKER, LAUREN BULLARO | Senior Vice President, Finance | 普通株式 | 売却 | 643 | $38.91 |
| 2023-06-14 | RIKER, LAUREN BULLARO | Senior Vice President, Finance | ストックオプション | 購入 | 25,000 | $0.00 |
| 2023-06-14 | KRONENFELD, MARK A. | Director | 普通株式 | 購入 | 1,775 | $0.00 |
| 2023-06-14 | PACE, GARY W | Director | ストックオプション | 購入 | 12,925 | $0.00 |
| 2023-06-14 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | ストックオプション | 購入 | 27,500 | $0.00 |
| 2023-06-14 | GAUGLER, DARYL | Chief Operating Officer | ストックオプション | 購入 | 25,000 | $0.00 |
| 2023-06-14 | GAUGLER, DARYL | Chief Operating Officer | 普通株式 | 購入 | 10,000 | $0.00 |
| 2023-06-14 | HASTINGS, PAUL J | Director | ストックオプション | 購入 | 12,925 | $0.00 |
| 2023-06-14 | HASTINGS, PAUL J | Director | 普通株式 | 購入 | 1,775 | $0.00 |
| 2023-06-14 | KRONENFELD, MARK A. | Director | ストックオプション | 購入 | 12,925 | $0.00 |
| 2023-06-14 | PACE, GARY W | Director | 普通株式 | 購入 | 1,775 | $0.00 |
| 2023-06-14 | REINHART, CHARLES A. III | Chief Financial Officer | ストックオプション | 購入 | 22,500 | $0.00 |
| 2023-06-14 | REINHART, CHARLES A. III | Chief Financial Officer | 普通株式 | 購入 | 9,000 | $0.00 |
| 2023-06-14 | RIKER, LAUREN BULLARO | Senior Vice President, Finance | 普通株式 | 売却 | 7 | $39.01 |
| 2023-06-14 | RIKER, LAUREN BULLARO | Senior Vice President, Finance | 普通株式 | 売却 | 5,773 | $38.52 |
| 2023-06-14 | FROIMSON, MARK | Director | 普通株式 | 購入 | 1,775 | $0.00 |
| 2023-06-14 | FROIMSON, MARK | Director | ストックオプション | 購入 | 12,925 | $0.00 |
| 2023-06-14 | CHRISTIE, CHRISTOPHER | Director | 普通株式 | 購入 | 1,775 | $0.00 |
| 2023-06-14 | CHRISTIE, CHRISTOPHER | Director | ストックオプション | 購入 | 12,925 | $0.00 |
| 2023-06-14 | BREGE, LAURA | Director | 普通株式 | 購入 | 1,775 | $0.00 |
| 2023-06-14 | BREGE, LAURA | Director | ストックオプション | 購入 | 12,925 | $0.00 |
| 2023-06-14 | RIKER, LAUREN BULLARO | Senior Vice President, Finance | 普通株式 | 売却 | 586 | $37.47 |
| 2023-06-14 | RIKER, LAUREN BULLARO | Senior Vice President, Finance | 普通株式 | 購入 | 10,000 | $0.00 |
| 2023-06-14 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 購入 | 245,400 | $0.00 |
| 2023-06-14 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 32,700 | $0.00 |
| 2023-06-14 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 売却 | 6,467 | $37.03 |
| 2023-06-14 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 購入 | 10,950 | $0.00 |
| 2023-06-14 | WINSTON, ROY | Chief Medical Officer | ストックオプション | 購入 | 27,500 | $0.00 |
| 2023-06-14 | WINSTON, ROY | Chief Medical Officer | 普通株式 | 購入 | 10,950 | $0.00 |
| 2023-06-08 | KRONENFELD, MARK A. | Director | 普通株式 | 購入 | 15,000 | $29.90 |
| 2023-06-08 | KRONENFELD, MARK A. | Director | ストックオプション | 売却 | 15,000 | $0.00 |
| 2023-06-08 | KRONENFELD, MARK A. | Director | 普通株式 | 売却 | 15,000 | $37.04 |
| 2023-06-07 | REINHARDT, MAX | President, Rest of World | 普通株式 | 売却 | 1,099 | $37.87 |
| 2023-06-07 | REINHART, CHARLES A. III | Chief Financial Officer | 普通株式 | 売却 | 1,371 | $37.87 |
| 2023-06-07 | GAUGLER, DARYL | Chief Operating Officer | 普通株式 | 売却 | 1,047 | $37.87 |
| 2023-06-07 | RIKER, LAUREN BULLARO | Senior Vice President, Finance | 普通株式 | 売却 | 616 | $37.87 |
| 2023-06-07 | MCLOUGHLIN, DENNIS | Chief Customer Officer | 普通株式 | 売却 | 1,057 | $37.87 |
| 2023-06-07 | SLONIN, JONATHAN | Chief Clinical Officer | 普通株式 | 売却 | 490 | $37.87 |
| 2023-06-07 | ELLIS, RONALD J. JR. | Chief Strategy Officer | 普通株式 | 売却 | 1,162 | $37.87 |
| 2023-06-07 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 5,326 | $37.87 |
| 2023-06-07 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 売却 | 1,357 | $37.87 |
| 2023-06-07 | WINSTON, ROY | Chief Medical Officer | 普通株式 | 売却 | 1,857 | $37.87 |
| 2023-06-06 | REINHARDT, MAX | President, Rest of World | 普通株式 | 売却 | 1,054 | $38.99 |
| 2023-06-06 | REINHART, CHARLES A. III | Chief Financial Officer | 普通株式 | 売却 | 1,236 | $38.99 |
| 2023-06-06 | RIKER, LAUREN BULLARO | Senior Vice President, Finance | 普通株式 | 売却 | 591 | $38.99 |
| 2023-06-06 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 5,058 | $38.99 |
| 2023-06-06 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 売却 | 1,301 | $38.99 |
| 2023-06-06 | WINSTON, ROY | Chief Medical Officer | 普通株式 | 売却 | 1,779 | $38.99 |
| 2023-06-06 | SLONIN, JONATHAN | Chief Clinical Officer | 普通株式 | 売却 | 471 | $38.99 |
| 2023-06-06 | MOLLOY, ANTHONY | Chief Lgl & Compliance Officer | 普通株式 | 売却 | 4,521 | $38.55 |
| 2023-06-06 | MCLOUGHLIN, DENNIS | Chief Customer Officer | 普通株式 | 売却 | 1,014 | $38.99 |
| 2023-06-06 | ELLIS, RONALD J. JR. | Chief Strategy Officer | 普通株式 | 売却 | 1,114 | $38.99 |
| 2023-06-06 | GAUGLER, DARYL | Chief Operating Officer | 普通株式 | 売却 | 1,005 | $38.99 |
| 2023-06-05 | BREGE, LAURA | Director | 普通株式 | 売却 | 600 | $38.74 |
| 2023-06-05 | MOLLOY, ANTHONY | Chief Lgl & Compliance Officer | 普通株式 | 売却 | 2,267 | $38.28 |
| 2023-06-05 | HASTINGS, PAUL J | Director | 普通株式 | 売却 | 580 | $38.34 |
| 2023-06-05 | GAUGLER, DARYL | Chief Operating Officer | 普通株式 | 売却 | 1,000 | $38.74 |
| 2023-05-31 | GAUGLER, DARYL | Chief Operating Officer | 普通株式 | 購入 | 2,500 | $34.00 |
| 2023-05-31 | GAUGLER, DARYL | Chief Operating Officer | 普通株式 | 売却 | 2,500 | $39.08 |
| 2023-05-31 | GAUGLER, DARYL | Chief Operating Officer | ストックオプション | 売却 | 2,500 | $0.00 |
| 2023-05-15 | HASTINGS, PAUL J | Director | 普通株式 | 売却 | 7,000 | $41.85 |
| 2023-05-15 | HASTINGS, PAUL J | Director | ストックオプション | 売却 | 7,000 | $0.00 |
| 2023-05-15 | HASTINGS, PAUL J | Director | 普通株式 | 購入 | 7,000 | $29.90 |
| 2023-05-11 | PACE, GARY W | Director | ストックオプション | 売却 | 7,000 | $0.00 |
| 2023-05-11 | PACE, GARY W | Director | 普通株式 | 購入 | 7,000 | $29.90 |
| 2023-05-11 | PACE, GARY W | Director | 普通株式 | 売却 | 5,015 | $41.78 |
| 2023-04-03 | BREGE, LAURA | Director | 普通株式 | 購入 | 7,000 | $29.90 |
| 2023-04-03 | BREGE, LAURA | Director | ストックオプション | 売却 | 7,000 | $0.00 |
| 2023-04-03 | BREGE, LAURA | Director | 普通株式 | 売却 | 7,000 | $40.72 |
| 2023-01-05 | MOLLOY, ANTHONY | Chief Lgl & Compliance Officer | 普通株式 | 売却 | 546 | $38.31 |
| 2023-01-04 | MOLLOY, ANTHONY | Chief Lgl & Compliance Officer | 普通株式 | 売却 | 158 | $39.09 |
| 2022-10-07 | REINHARDT, MAX | President, Rest of World | 普通株式 | 売却 | 1,380 | $58.00 |
| 2022-08-03 | SLONIN, JONATHAN | Chief Clinical Officer | 普通株式 | 売却 | 308 | $55.70 |
| 2022-08-03 | WINSTON, ROY | Chief Medical Officer | 普通株式 | 売却 | 476 | $55.70 |
| 2022-07-11 | HASTINGS, PAUL J | Director | 普通株式 | 売却 | 533 | $56.95 |
| 2022-07-05 | SLONIN, JONATHAN | Chief Clinical Officer | 普通株式 | 売却 | 924 | $57.19 |
| 2022-06-14 | LARANJEIRA, CHARLES ANTHONY | Chief Technical Officer | ストックオプション | 売却 | 6,000 | $0.00 |
| 2022-06-14 | LARANJEIRA, CHARLES ANTHONY | Chief Technical Officer | 普通株式 | 購入 | 6,000 | $38.35 |
| 2022-06-08 | GAUGLER, DARYL | Chief Operating Officer | ストックオプション | 購入 | 19,800 | $0.00 |
| 2022-06-08 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 21,500 | $0.00 |
| 2022-06-08 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 購入 | 160,900 | $0.00 |
| 2022-06-08 | GAUGLER, DARYL | Chief Operating Officer | 普通株式 | 購入 | 5,000 | $0.00 |
| 2022-06-08 | GAUGLER, DARYL | Chief Operating Officer | ストックオプション | 購入 | 10,000 | $0.00 |
| 2022-06-08 | FROIMSON, MARK | Director | 普通株式 | 購入 | 1,160 | $0.00 |
| 2022-06-08 | FROIMSON, MARK | Director | ストックオプション | 購入 | 8,225 | $0.00 |
| 2022-06-08 | CHRISTIE, CHRISTOPHER | Director | 普通株式 | 購入 | 1,160 | $0.00 |
| 2022-06-08 | CHRISTIE, CHRISTOPHER | Director | ストックオプション | 購入 | 8,225 | $0.00 |
| 2022-06-08 | BREGE, LAURA | Director | 普通株式 | 購入 | 1,160 | $0.00 |
| 2022-06-08 | BREGE, LAURA | Director | ストックオプション | 購入 | 8,225 | $0.00 |
| 2022-06-08 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 7,039 | $59.10 |
| 2022-06-08 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 5,006 | $60.33 |
| 2022-06-08 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 1,282 | $61.31 |
| 2022-06-08 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 501 | $61.96 |
| 2022-06-08 | WINSTON, ROY | Chief Medical Officer | 普通株式 | 購入 | 9,900 | $0.00 |
| 2022-06-08 | WINSTON, ROY | Chief Medical Officer | ストックオプション | 購入 | 24,800 | $0.00 |
| 2022-06-08 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 購入 | 9,900 | $0.00 |
| 2022-06-08 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | ストックオプション | 購入 | 24,800 | $0.00 |
| 2022-06-08 | SLONIN, JONATHAN | Chief Clinical Officer | 普通株式 | 購入 | 9,900 | $0.00 |
| 2022-06-08 | SLONIN, JONATHAN | Chief Clinical Officer | ストックオプション | 購入 | 24,800 | $0.00 |
| 2022-06-08 | RIKER, LAUREN BULLARO | Senior Vice President, Finance | 普通株式 | 購入 | 5,850 | $0.00 |
| 2022-06-08 | RIKER, LAUREN BULLARO | Senior Vice President, Finance | ストックオプション | 購入 | 14,600 | $0.00 |
| 2022-06-08 | REINHART, CHARLES A. III | Chief Financial Officer | 普通株式 | 購入 | 7,950 | $0.00 |
| 2022-06-08 | REINHART, CHARLES A. III | Chief Financial Officer | ストックオプション | 購入 | 19,900 | $0.00 |
| 2022-06-08 | REINHARDT, MAX | President, Rest of World | 普通株式 | 購入 | 7,950 | $0.00 |
| 2022-06-08 | REINHARDT, MAX | President, Rest of World | ストックオプション | 購入 | 19,900 | $0.00 |
| 2022-06-08 | LARANJEIRA, CHARLES ANTHONY | Chief Technical Officer | 普通株式 | 売却 | 2,521 | $59.08 |
| 2022-06-08 | LARANJEIRA, CHARLES ANTHONY | Chief Technical Officer | 普通株式 | 売却 | 1,633 | $60.23 |
| 2022-06-08 | LARANJEIRA, CHARLES ANTHONY | Chief Technical Officer | 普通株式 | 売却 | 516 | $60.99 |
| 2022-06-08 | LARANJEIRA, CHARLES ANTHONY | Chief Technical Officer | 普通株式 | 売却 | 267 | $61.98 |
| 2022-06-08 | LARANJEIRA, CHARLES ANTHONY | Chief Technical Officer | 普通株式 | 購入 | 9,900 | $0.00 |
| 2022-06-08 | LARANJEIRA, CHARLES ANTHONY | Chief Technical Officer | ストックオプション | 購入 | 24,800 | $0.00 |
| 2022-06-08 | PACE, GARY W | Director | 普通株式 | 購入 | 1,160 | $0.00 |
| 2022-06-08 | PACE, GARY W | Director | ストックオプション | 購入 | 8,225 | $0.00 |
| 2022-06-08 | MOLLOY, ANTHONY | Chief Lgl & Compliance Officer | 普通株式 | 購入 | 7,950 | $0.00 |
| 2022-06-08 | MOLLOY, ANTHONY | Chief Lgl & Compliance Officer | ストックオプション | 購入 | 19,900 | $0.00 |
| 2022-06-08 | MCLOUGHLIN, DENNIS | Chief Customer Officer | 普通株式 | 購入 | 7,950 | $0.00 |
| 2022-06-08 | MCLOUGHLIN, DENNIS | Chief Customer Officer | ストックオプション | 購入 | 19,900 | $0.00 |
| 2022-06-08 | KRONENFELD, MARK A. | Director | 普通株式 | 購入 | 1,160 | $0.00 |
| 2022-06-08 | KRONENFELD, MARK A. | Director | ストックオプション | 購入 | 8,225 | $0.00 |
| 2022-06-08 | HASTINGS, PAUL J | Director | 普通株式 | 購入 | 1,160 | $0.00 |
| 2022-06-08 | HASTINGS, PAUL J | Director | ストックオプション | 購入 | 8,225 | $0.00 |
| 2022-06-08 | GREENSTREET, YVONNE | Director | 普通株式 | 購入 | 1,160 | $0.00 |
| 2022-06-08 | GREENSTREET, YVONNE | Director | ストックオプション | 購入 | 8,225 | $0.00 |
| 2022-06-08 | GAUGLER, DARYL | Chief Operating Officer | 普通株式 | 購入 | 7,900 | $0.00 |
| 2022-06-07 | REINHARDT, MAX | President, Rest of World | 普通株式 | 売却 | 2,433 | $62.00 |
| 2022-06-07 | MOLLOY, ANTHONY | Chief Lgl & Compliance Officer | 普通株式 | 売却 | 1,830 | $60.40 |
| 2022-06-07 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 売却 | 4,649 | $59.51 |
| 2022-06-07 | MOLLOY, ANTHONY | Chief Lgl & Compliance Officer | 普通株式 | 売却 | 740 | $59.38 |
| 2022-06-06 | WINSTON, ROY | Chief Medical Officer | 普通株式 | 売却 | 1,300 | $62.43 |
| 2022-06-06 | WINSTON, ROY | Chief Medical Officer | 普通株式 | 売却 | 115 | $63.40 |
| 2022-06-06 | WINSTON, ROY | Chief Medical Officer | 普通株式 | 売却 | 3,533 | $60.55 |
| 2022-06-06 | WINSTON, ROY | Chief Medical Officer | 普通株式 | 売却 | 3,650 | $61.59 |
| 2022-06-06 | WINSTON, ROY | Chief Medical Officer | 普通株式 | 売却 | 1,891 | $62.48 |
| 2022-06-06 | WINSTON, ROY | Chief Medical Officer | 普通株式 | 売却 | 123 | $63.69 |
| 2022-06-06 | WINSTON, ROY | Chief Medical Officer | 普通株式 | 購入 | 6,250 | $34.38 |
| 2022-06-06 | WINSTON, ROY | Chief Medical Officer | 普通株式 | 売却 | 2,099 | $61.37 |
| 2022-06-06 | RIKER, LAUREN BULLARO | Senior Vice President, Finance | 普通株式 | 売却 | 1,150 | $61.37 |
| 2022-06-06 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 売却 | 3,969 | $61.37 |
| 2022-06-06 | WINSTON, ROY | Chief Medical Officer | 普通株式 | 売却 | 2,535 | $60.55 |
| 2022-06-06 | WINSTON, ROY | Chief Medical Officer | 普通株式 | 売却 | 2,300 | $61.59 |
| 2022-06-06 | MOLLOY, ANTHONY | Chief Lgl & Compliance Officer | 普通株式 | 売却 | 2,980 | $61.37 |
| 2022-06-06 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 11,965 | $61.37 |
| 2022-06-06 | GAUGLER, DARYL | Chief Operating Officer | 普通株式 | 売却 | 1,106 | $61.37 |
| 2022-06-06 | WINSTON, ROY | Chief Medical Officer | ストックオプション | 売却 | 6,250 | $0.00 |
| 2022-06-06 | MCLOUGHLIN, DENNIS | Chief Customer Officer | 普通株式 | 売却 | 2,140 | $61.37 |
| 2022-06-06 | LARANJEIRA, CHARLES ANTHONY | Chief Technical Officer | 普通株式 | 売却 | 2,813 | $61.37 |
| 2022-06-06 | REINHARDT, MAX | President, Rest of World | 普通株式 | 売却 | 2,817 | $61.37 |
| 2022-06-06 | REINHART, CHARLES A. III | Chief Financial Officer | 普通株式 | 売却 | 2,516 | $61.37 |
| 2022-06-06 | SLONIN, JONATHAN | Chief Clinical Officer | 普通株式 | 売却 | 362 | $61.37 |
| 2022-05-23 | SLONIN, JONATHAN | Chief Clinical Officer | ストックオプション | 売却 | 2,000 | $0.00 |
| 2022-05-23 | SLONIN, JONATHAN | Chief Clinical Officer | 普通株式 | 購入 | 2,000 | $52.37 |
| 2022-05-09 | FROIMSON, MARK | Director | 普通株式 | 売却 | 1,000 | $59.37 |
| 2022-04-28 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 22,500 | $10.81 |
| 2022-04-28 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 22,500 | $0.00 |
| 2022-04-21 | REINHARDT, MAX | President, Rest of World | ストックオプション | 売却 | 12,500 | $0.00 |
| 2022-04-21 | REINHARDT, MAX | President, Rest of World | 普通株式 | 売却 | 9,824 | $73.25 |
| 2022-04-21 | REINHARDT, MAX | President, Rest of World | 普通株式 | 購入 | 12,500 | $42.54 |
| 2022-04-20 | REINHARDT, MAX | President, Rest of World | 普通株式 | 購入 | 12,500 | $42.54 |
| 2022-04-20 | REINHARDT, MAX | President, Rest of World | ストックオプション | 売却 | 12,500 | $0.00 |
| 2022-04-20 | REINHARDT, MAX | President, Rest of World | 普通株式 | 売却 | 9,764 | $73.99 |
| 2022-04-19 | REINHARDT, MAX | President, Rest of World | ストックオプション | 売却 | 12,500 | $0.00 |
| 2022-04-19 | REINHARDT, MAX | President, Rest of World | 普通株式 | 売却 | 9,321 | $72.25 |
| 2022-04-19 | REINHARDT, MAX | President, Rest of World | 普通株式 | 購入 | 12,500 | $42.54 |
| 2022-04-18 | REINHARDT, MAX | President, Rest of World | 普通株式 | 購入 | 12,500 | $42.54 |
| 2022-04-18 | REINHARDT, MAX | President, Rest of World | ストックオプション | 売却 | 12,500 | $0.00 |
| 2022-04-18 | REINHARDT, MAX | President, Rest of World | 普通株式 | 売却 | 8,941 | $73.55 |
| 2022-04-06 | MOLLOY, ANTHONY | Chief Lgl & Compliance Officer | ストックオプション | 売却 | 2,500 | $0.00 |
| 2022-04-06 | MOLLOY, ANTHONY | Chief Lgl & Compliance Officer | ストックオプション | 売却 | 3,000 | $0.00 |
| 2022-04-06 | MOLLOY, ANTHONY | Chief Lgl & Compliance Officer | 普通株式 | 売却 | 2,503 | $77.94 |
| 2022-04-06 | MOLLOY, ANTHONY | Chief Lgl & Compliance Officer | 普通株式 | 購入 | 10,000 | $44.20 |
| 2022-04-06 | MOLLOY, ANTHONY | Chief Lgl & Compliance Officer | 普通株式 | 購入 | 2,500 | $34.38 |
| 2022-04-06 | MOLLOY, ANTHONY | Chief Lgl & Compliance Officer | 普通株式 | 購入 | 7,000 | $38.35 |
| 2022-04-06 | MOLLOY, ANTHONY | Chief Lgl & Compliance Officer | 普通株式 | 売却 | 16,060 | $76.03 |
| 2022-04-06 | MOLLOY, ANTHONY | Chief Lgl & Compliance Officer | 普通株式 | 売却 | 3,937 | $77.03 |
| 2022-04-06 | MOLLOY, ANTHONY | Chief Lgl & Compliance Officer | 普通株式 | 購入 | 3,000 | $40.34 |
| 2022-04-06 | MOLLOY, ANTHONY | Chief Lgl & Compliance Officer | ストックオプション | 売却 | 7,000 | $0.00 |
| 2022-04-06 | MOLLOY, ANTHONY | Chief Lgl & Compliance Officer | ストックオプション | 売却 | 10,000 | $0.00 |
| 2022-03-31 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 22,500 | $0.00 |
| 2022-03-31 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 22,500 | $10.81 |
| 2022-03-21 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | ストックオプション | 売却 | 2,112 | $0.00 |
| 2022-03-21 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 売却 | 7,253 | $72.67 |
| 2022-03-21 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 購入 | 2,953 | $38.35 |
| 2022-03-21 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 購入 | 2,112 | $43.54 |
| 2022-03-21 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | ストックオプション | 売却 | 2,188 | $0.00 |
| 2022-03-21 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 購入 | 2,188 | $47.65 |
| 2022-03-21 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | ストックオプション | 売却 | 2,953 | $0.00 |
| 2022-03-10 | RIKER, LAUREN BULLARO | Senior Vice President, Finance | 普通株式 | 売却 | 8,400 | $71.14 |
| 2022-03-10 | RIKER, LAUREN BULLARO | Senior Vice President, Finance | 普通株式 | 購入 | 9,300 | $10.81 |
| 2022-03-10 | RIKER, LAUREN BULLARO | Senior Vice President, Finance | ストックオプション | 売却 | 9,300 | $0.00 |
| 2022-03-10 | RIKER, LAUREN BULLARO | Senior Vice President, Finance | 普通株式 | 売却 | 900 | $71.95 |
| 2022-03-03 | PACE, GARY W | Director | 普通株式 | 購入 | 7,000 | $10.81 |
| 2022-03-03 | LONGENECKER, JOHN P PHD | Director | ストックオプション | 売却 | 7,000 | $0.00 |
| 2022-03-03 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 売却 | 7,000 | $71.74 |
| 2022-03-03 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 購入 | 7,000 | $10.81 |
| 2022-03-03 | PACE, GARY W | Director | ストックオプション | 売却 | 7,000 | $0.00 |
| 2022-03-01 | PACE, GARY W | Director | 普通株式 | 売却 | 1,359 | $67.75 |
| 2022-03-01 | PACE, GARY W | Director | ストックオプション | 売却 | 193 | $0.00 |
| 2022-03-01 | PACE, GARY W | Director | ストックオプション | 売却 | 1,166 | $0.00 |
| 2022-03-01 | PACE, GARY W | Director | 普通株式 | 購入 | 1,166 | $11.02 |
| 2022-03-01 | PACE, GARY W | Director | 普通株式 | 購入 | 193 | $11.02 |
| 2022-02-28 | PACE, GARY W | Director | 普通株式 | 購入 | 9,807 | $11.02 |
| 2022-02-28 | PACE, GARY W | Director | 普通株式 | 売却 | 28,641 | $66.83 |
| 2022-02-28 | PACE, GARY W | Director | ストックオプション | 売却 | 9,807 | $0.00 |
| 2022-02-28 | PACE, GARY W | Director | ストックオプション | 売却 | 18,834 | $0.00 |
| 2022-02-28 | PACE, GARY W | Director | 普通株式 | 購入 | 18,834 | $11.02 |
| 2022-02-25 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | ストックオプション | 売却 | 2,050 | $0.00 |
| 2022-02-25 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 売却 | 2,000 | $67.07 |
| 2022-02-25 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 売却 | 50 | $65.00 |
| 2022-02-25 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 購入 | 2,050 | $38.35 |
| 2022-02-16 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | ストックオプション | 売却 | 10 | $0.00 |
| 2022-02-16 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 購入 | 10 | $38.35 |
| 2022-02-16 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 売却 | 10 | $65.00 |
| 2022-02-10 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | ストックオプション | 売却 | 800 | $0.00 |
| 2022-02-10 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 売却 | 800 | $65.18 |
| 2022-02-10 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 購入 | 800 | $38.35 |
| 2022-02-04 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 売却 | 1,000 | $65.18 |
| 2022-02-04 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 購入 | 1,000 | $38.35 |
| 2022-02-04 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | ストックオプション | 売却 | 1,000 | $0.00 |
| 2022-01-25 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 13,670 | $0.00 |
| 2022-01-25 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 13,670 | $10.81 |
| 2022-01-21 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 購入 | 200 | $38.35 |
| 2022-01-21 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | ストックオプション | 売却 | 200 | $0.00 |
| 2022-01-21 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 売却 | 200 | $65.41 |
| 2022-01-19 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 売却 | 2,199 | $65.51 |
| 2022-01-19 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | ストックオプション | 売却 | 2,199 | $0.00 |
| 2022-01-19 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 購入 | 2,199 | $38.35 |
| 2022-01-18 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | ストックオプション | 売却 | 2,600 | $0.00 |
| 2022-01-18 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 売却 | 400 | $66.14 |
| 2022-01-18 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 売却 | 23,040 | $65.24 |
| 2022-01-18 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | ストックオプション | 売却 | 1,375 | $0.00 |
| 2022-01-18 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 購入 | 13,127 | $47.65 |
| 2022-01-18 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 購入 | 6,338 | $43.54 |
| 2022-01-18 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 購入 | 2,600 | $38.35 |
| 2022-01-18 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 購入 | 1,375 | $44.20 |
| 2022-01-18 | MOLLOY, ANTHONY | Chief Lgl & Compliance Officer | 普通株式 | 売却 | 224 | $63.55 |
| 2022-01-18 | RIKER, LAUREN BULLARO | Senior Vice President, Finance | ストックオプション | 売却 | 2,500 | $0.00 |
| 2022-01-18 | RIKER, LAUREN BULLARO | Senior Vice President, Finance | 普通株式 | 売却 | 2,500 | $64.97 |
| 2022-01-18 | RIKER, LAUREN BULLARO | Senior Vice President, Finance | 普通株式 | 購入 | 2,500 | $10.81 |
| 2022-01-18 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | ストックオプション | 売却 | 13,127 | $0.00 |
| 2022-01-18 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | ストックオプション | 売却 | 6,338 | $0.00 |
| 2022-01-11 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 15,000 | $0.00 |
| 2022-01-11 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 15,000 | $10.81 |
| 2022-01-04 | MOLLOY, ANTHONY | Chief Lgl & Compliance Officer | ストックオプション | 購入 | 5,000 | $0.00 |
| 2022-01-04 | RIKER, LAUREN BULLARO | Senior Vice President, Finance | 普通株式 | 購入 | 2,000 | $0.00 |
| 2022-01-04 | RIKER, LAUREN BULLARO | Senior Vice President, Finance | ストックオプション | 購入 | 5,000 | $0.00 |
| 2022-01-04 | MOLLOY, ANTHONY | Chief Lgl & Compliance Officer | 普通株式 | 購入 | 2,000 | $0.00 |
| 2021-12-17 | FROIMSON, MARK | Director | 普通株式 | 売却 | 400 | $0.00 |
| 2021-11-22 | LARANJEIRA, CHARLES ANTHONY | Chief Technical Officer | ストックオプション | 売却 | 7,500 | $0.00 |
| 2021-11-22 | LARANJEIRA, CHARLES ANTHONY | Chief Technical Officer | 普通株式 | 購入 | 7,500 | $44.10 |
| 2021-11-16 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 15,000 | $0.00 |
| 2021-11-16 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 15,000 | $10.81 |
| 2021-11-04 | WINSTON, ROY | Chief Medical Officer | 普通株式 | 購入 | 10,000 | $48.15 |
| 2021-11-04 | WINSTON, ROY | Chief Medical Officer | ストックオプション | 売却 | 10,000 | $0.00 |
| 2021-08-03 | WINSTON, ROY | Chief Medical Officer | 普通株式 | 購入 | 5,000 | $0.00 |
| 2021-08-03 | SLONIN, JONATHAN | Chief Clinical Officer | 普通株式 | 購入 | 5,000 | $0.00 |
| 2021-08-03 | SLONIN, JONATHAN | Chief Clinical Officer | ストックオプション | 購入 | 10,000 | $0.00 |
| 2021-08-03 | WINSTON, ROY | Chief Medical Officer | ストックオプション | 購入 | 10,000 | $0.00 |
| 2021-07-29 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 売却 | 90 | $60.81 |
| 2021-07-29 | RIKER, LAUREN BULLARO | Vice President, Finance | ストックオプション | 売却 | 90 | $0.00 |
| 2021-07-29 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 購入 | 90 | $10.81 |
| 2021-07-28 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 購入 | 2,410 | $10.81 |
| 2021-07-28 | RIKER, LAUREN BULLARO | Vice President, Finance | ストックオプション | 売却 | 2,410 | $0.00 |
| 2021-07-28 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 売却 | 2,410 | $60.85 |
| 2021-07-02 | REINHARDT, MAX | President, Rest of World | 普通株式 | 売却 | 421 | $59.76 |
| 2021-06-11 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 売却 | 2,003 | $59.85 |
| 2021-06-10 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 売却 | 847 | $60.57 |
| 2021-06-10 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 売却 | 4,842 | $59.43 |
| 2021-06-09 | GREENSTREET, YVONNE | Director | ストックオプション | 購入 | 7,626 | $0.00 |
| 2021-06-09 | KRONENFELD, MARK A. | Director | 普通株式 | 購入 | 1,066 | $0.00 |
| 2021-06-09 | LARANJEIRA, CHARLES ANTHONY | Chief Technical Officer | ストックオプション | 購入 | 17,500 | $0.00 |
| 2021-06-09 | LARANJEIRA, CHARLES ANTHONY | Chief Technical Officer | 普通株式 | 購入 | 7,000 | $0.00 |
| 2021-06-09 | LONGENECKER, JOHN P PHD | Director | ストックオプション | 購入 | 7,626 | $0.00 |
| 2021-06-09 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 購入 | 1,066 | $0.00 |
| 2021-06-09 | MANNING, DONALD C. | Chief Medical Officer | ストックオプション | 購入 | 15,000 | $0.00 |
| 2021-06-09 | MANNING, DONALD C. | Chief Medical Officer | 普通株式 | 購入 | 6,000 | $0.00 |
| 2021-06-09 | WINSTON, ROY | Chief Clinical Officer | ストックオプション | 購入 | 17,500 | $0.00 |
| 2021-06-09 | WINSTON, ROY | Chief Clinical Officer | 普通株式 | 購入 | 7,000 | $0.00 |
| 2021-06-09 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | ストックオプション | 購入 | 17,500 | $0.00 |
| 2021-06-09 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 購入 | 7,000 | $0.00 |
| 2021-06-09 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 17,800 | $0.00 |
| 2021-06-09 | REINHARDT, MAX | President, Rest of World | 普通株式 | 購入 | 7,000 | $0.00 |
| 2021-06-09 | PACE, GARY W | Director | ストックオプション | 購入 | 7,626 | $0.00 |
| 2021-06-09 | PACE, GARY W | Director | 普通株式 | 購入 | 1,066 | $0.00 |
| 2021-06-09 | MCLOUGHLIN, DENNIS | Chief Customer Officer | ストックオプション | 購入 | 15,000 | $0.00 |
| 2021-06-09 | MCLOUGHLIN, DENNIS | Chief Customer Officer | 普通株式 | 購入 | 6,000 | $0.00 |
| 2021-06-09 | KRONENFELD, MARK A. | Director | ストックオプション | 購入 | 7,626 | $0.00 |
| 2021-06-09 | FROIMSON, MARK | Director | 普通株式 | 購入 | 1,066 | $0.00 |
| 2021-06-09 | FROIMSON, MARK | Director | ストックオプション | 購入 | 7,626 | $0.00 |
| 2021-06-09 | CHRISTIE, CHRISTOPHER | Director | 普通株式 | 購入 | 1,066 | $0.00 |
| 2021-06-09 | CHRISTIE, CHRISTOPHER | Director | ストックオプション | 購入 | 7,626 | $0.00 |
| 2021-06-09 | BREGE, LAURA | Director | 普通株式 | 購入 | 1,066 | $0.00 |
| 2021-06-09 | BREGE, LAURA | Director | ストックオプション | 購入 | 7,626 | $0.00 |
| 2021-06-09 | REINHARDT, MAX | President, Rest of World | ストックオプション | 購入 | 17,500 | $0.00 |
| 2021-06-09 | REINHART, CHARLES A. III | Chief Financial Officer | 普通株式 | 購入 | 6,000 | $0.00 |
| 2021-06-09 | REINHART, CHARLES A. III | Chief Financial Officer | ストックオプション | 購入 | 15,000 | $0.00 |
| 2021-06-09 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 購入 | 2,600 | $0.00 |
| 2021-06-09 | RIKER, LAUREN BULLARO | Vice President, Finance | ストックオプション | 購入 | 6,500 | $0.00 |
| 2021-06-09 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 購入 | 133,400 | $0.00 |
| 2021-06-09 | GREENSTREET, YVONNE | Director | 普通株式 | 購入 | 1,066 | $0.00 |
| 2021-06-09 | HASTINGS, PAUL J | Director | ストックオプション | 購入 | 7,626 | $0.00 |
| 2021-06-09 | HASTINGS, PAUL J | Director | 普通株式 | 購入 | 1,066 | $0.00 |
| 2021-06-08 | MANNING, DONALD C. | Chief Medical Officer | 普通株式 | 売却 | 2,600 | $61.14 |
| 2021-06-07 | REINHARDT, MAX | President, Rest of World | 普通株式 | 売却 | 2,278 | $60.50 |
| 2021-06-04 | WINSTON, ROY | Chief Clinical Officer | 普通株式 | 売却 | 2,276 | $61.04 |
| 2021-06-04 | REINHART, CHARLES A. III | Chief Financial Officer | 普通株式 | 売却 | 2,648 | $61.04 |
| 2021-06-04 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 14,905 | $61.04 |
| 2021-06-04 | LARANJEIRA, CHARLES ANTHONY | Chief Technical Officer | 普通株式 | 売却 | 2,117 | $61.04 |
| 2021-06-04 | REINHARDT, MAX | President, Rest of World | 普通株式 | 売却 | 1,222 | $61.04 |
| 2021-06-04 | HASTINGS, PAUL J | Director | 普通株式 | 売却 | 630 | $62.19 |
| 2021-06-04 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 売却 | 3,930 | $61.04 |
| 2021-06-04 | MCLOUGHLIN, DENNIS | Chief Customer Officer | 普通株式 | 売却 | 1,895 | $61.04 |
| 2021-06-04 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 売却 | 1,047 | $61.04 |
| 2021-06-02 | MANNING, DONALD C. | Chief Medical Officer | 普通株式 | 売却 | 2,380 | $62.12 |
| 2021-05-13 | PACE, GARY W | Director | 普通株式 | 売却 | 1,485 | $0.00 |
| 2021-05-12 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 21,250 | $0.00 |
| 2021-05-12 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 3,611 | $62.41 |
| 2021-05-12 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 14,669 | $62.08 |
| 2021-05-12 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 2,970 | $60.76 |
| 2021-05-12 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 21,250 | $10.81 |
| 2021-05-11 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 21,250 | $10.81 |
| 2021-05-11 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 13,318 | $60.78 |
| 2021-05-11 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 21,250 | $0.00 |
| 2021-05-11 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 7,932 | $61.19 |
| 2021-04-13 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 購入 | 6,339 | $43.54 |
| 2021-04-13 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 売却 | 14,793 | $66.40 |
| 2021-04-13 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 購入 | 8,859 | $38.35 |
| 2021-04-13 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 購入 | 4,125 | $44.20 |
| 2021-04-13 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | ストックオプション | 売却 | 6,339 | $0.00 |
| 2021-04-13 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 売却 | 7,030 | $68.11 |
| 2021-04-13 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 購入 | 2,500 | $32.35 |
| 2021-04-13 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | ストックオプション | 売却 | 8,859 | $0.00 |
| 2021-04-13 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | ストックオプション | 売却 | 2,500 | $0.00 |
| 2021-04-13 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | ストックオプション | 売却 | 4,125 | $0.00 |
| 2021-03-31 | WINSTON, ROY | Chief Clinical Officer | 普通株式 | 売却 | 1,200 | $72.12 |
| 2021-03-31 | WINSTON, ROY | Chief Clinical Officer | 普通株式 | 売却 | 4,661 | $71.09 |
| 2021-03-31 | WINSTON, ROY | Chief Clinical Officer | ストックオプション | 売却 | 13,750 | $0.00 |
| 2021-03-31 | WINSTON, ROY | Chief Clinical Officer | 普通株式 | 売却 | 16,363 | $70.36 |
| 2021-03-31 | WINSTON, ROY | Chief Clinical Officer | 普通株式 | 購入 | 13,750 | $34.38 |
| 2021-03-24 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 1,080 | $0.00 |
| 2021-03-17 | RIKER, LAUREN BULLARO | Vice President, Finance | ストックオプション | 売却 | 2,000 | $0.00 |
| 2021-03-17 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 購入 | 2,000 | $10.81 |
| 2021-03-17 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 売却 | 2,000 | $70.01 |
| 2021-03-15 | FROIMSON, MARK | Director | 普通株式 | 売却 | 734 | $72.26 |
| 2021-03-15 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 売却 | 1,520 | $73.28 |
| 2021-03-15 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 購入 | 1,520 | $10.81 |
| 2021-03-15 | RIKER, LAUREN BULLARO | Vice President, Finance | ストックオプション | 売却 | 1,520 | $0.00 |
| 2021-03-15 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 10,601 | $73.68 |
| 2021-03-12 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 58,754 | $73.10 |
| 2021-03-11 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 60,574 | $72.70 |
| 2021-03-10 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 76,480 | $71.78 |
| 2021-03-09 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 35,137 | $70.90 |
| 2021-03-05 | HASTINGS, PAUL J | Director | ストックオプション | 売却 | 3,000 | $0.00 |
| 2021-03-05 | HASTINGS, PAUL J | Director | 普通株式 | 購入 | 3,000 | $13.98 |
| 2021-03-05 | HASTINGS, PAUL J | Director | 普通株式 | 売却 | 3,000 | $65.88 |
| 2021-03-01 | LONGENECKER, JOHN P PHD | Director | ストックオプション | 売却 | 5,000 | $0.00 |
| 2021-03-01 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 売却 | 5,000 | $72.26 |
| 2021-03-01 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 購入 | 5,000 | $13.98 |
| 2021-02-03 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 21,250 | $0.00 |
| 2021-02-03 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 6,900 | $70.78 |
| 2021-02-03 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 21,250 | $10.81 |
| 2021-02-03 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 14,350 | $71.42 |
| 2021-02-02 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 21,250 | $0.00 |
| 2021-02-02 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 4,100 | $70.20 |
| 2021-02-02 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 2,900 | $68.41 |
| 2021-02-02 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 14,250 | $69.38 |
| 2021-02-02 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 21,250 | $10.81 |
| 2021-01-06 | REINHARDT, MAX | President | 普通株式 | 売却 | 110 | $60.81 |
| 2020-11-16 | BREGE, LAURA | Director | 普通株式 | 購入 | 12,000 | $13.98 |
| 2020-11-16 | BREGE, LAURA | Director | 普通株式 | 売却 | 12,000 | $65.95 |
| 2020-11-16 | BREGE, LAURA | Director | ストックオプション | 売却 | 12,000 | $0.00 |
| 2020-11-13 | WINSTON, ROY | Chief Clinical Officer | 普通株式 | 売却 | 5,000 | $62.00 |
| 2020-11-13 | RIKER, LAUREN BULLARO | Vice President, Finance | ストックオプション | 売却 | 3,000 | $0.00 |
| 2020-11-13 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 売却 | 3,000 | $63.81 |
| 2020-11-13 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 購入 | 3,000 | $10.81 |
| 2020-11-13 | REINHARDT, MAX | President | ストックオプション | 売却 | 25,000 | $0.00 |
| 2020-11-13 | REINHARDT, MAX | President | 普通株式 | 売却 | 21,000 | $63.51 |
| 2020-11-13 | REINHARDT, MAX | President | 普通株式 | 売却 | 4,000 | $62.67 |
| 2020-11-13 | REINHARDT, MAX | President | 普通株式 | 購入 | 25,000 | $42.54 |
| 2020-10-16 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 30,000 | $0.00 |
| 2020-10-16 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 30,000 | $10.81 |
| 2020-10-16 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 30,000 | $55.56 |
| 2020-10-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 30,000 | $55.00 |
| 2020-10-15 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 30,000 | $0.00 |
| 2020-10-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 30,000 | $10.81 |
| 2020-10-14 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 30,000 | $0.00 |
| 2020-10-14 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 30,000 | $55.53 |
| 2020-10-14 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 30,000 | $10.81 |
| 2020-09-25 | PACE, GARY W | Director | 普通株式 | 購入 | 70,000 | $16.67 |
| 2020-09-25 | PACE, GARY W | Director | ストックオプション | 売却 | 70,000 | $0.00 |
| 2020-09-17 | REINHARDT, MAX | President | ストックオプション | 売却 | 25,000 | $0.00 |
| 2020-09-17 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | ストックオプション | 売却 | 2,819 | $0.00 |
| 2020-09-17 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | ストックオプション | 売却 | 7,878 | $0.00 |
| 2020-09-17 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | ストックオプション | 売却 | 5,502 | $0.00 |
| 2020-09-17 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | ストックオプション | 売却 | 5,836 | $0.00 |
| 2020-09-17 | REINHARDT, MAX | President | 普通株式 | 購入 | 25,000 | $42.54 |
| 2020-09-17 | REINHARDT, MAX | President | 普通株式 | 売却 | 22,532 | $59.75 |
| 2020-09-17 | REINHARDT, MAX | President | 普通株式 | 売却 | 2,888 | $60.26 |
| 2020-09-17 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 売却 | 3,200 | $60.22 |
| 2020-09-17 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 売却 | 24,671 | $59.77 |
| 2020-09-17 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 購入 | 2,819 | $43.54 |
| 2020-09-17 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 購入 | 7,878 | $38.35 |
| 2020-09-17 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 購入 | 5,502 | $44.20 |
| 2020-09-17 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 購入 | 5,836 | $32.35 |
| 2020-09-17 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 購入 | 5,836 | $40.34 |
| 2020-09-16 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 購入 | 3,000 | $10.81 |
| 2020-09-16 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | ストックオプション | 売却 | 7,874 | $0.00 |
| 2020-09-16 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | ストックオプション | 売却 | 5,499 | $0.00 |
| 2020-09-16 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | ストックオプション | 売却 | 5,832 | $0.00 |
| 2020-09-16 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 購入 | 7,874 | $38.35 |
| 2020-09-16 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 売却 | 3,000 | $60.34 |
| 2020-09-16 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 売却 | 21,244 | $60.33 |
| 2020-09-16 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 購入 | 5,832 | $32.35 |
| 2020-09-16 | RIKER, LAUREN BULLARO | Vice President, Finance | ストックオプション | 売却 | 3,000 | $0.00 |
| 2020-09-16 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 購入 | 5,499 | $44.20 |
| 2020-09-16 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 売却 | 6,609 | $59.54 |
| 2020-09-16 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 購入 | 5,832 | $40.34 |
| 2020-09-16 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 購入 | 2,816 | $43.54 |
| 2020-09-16 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | ストックオプション | 売却 | 2,816 | $0.00 |
| 2020-09-15 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 購入 | 2,816 | $43.54 |
| 2020-09-15 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | ストックオプション | 売却 | 2,816 | $0.00 |
| 2020-09-15 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | ストックオプション | 売却 | 7,874 | $0.00 |
| 2020-09-15 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | ストックオプション | 売却 | 5,499 | $0.00 |
| 2020-09-15 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | ストックオプション | 売却 | 5,832 | $0.00 |
| 2020-09-15 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 売却 | 14,622 | $59.01 |
| 2020-09-15 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 購入 | 7,874 | $38.35 |
| 2020-09-15 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 購入 | 5,499 | $44.20 |
| 2020-09-15 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 購入 | 5,832 | $32.35 |
| 2020-09-15 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 購入 | 5,832 | $40.34 |
| 2020-09-15 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 売却 | 13,231 | $59.80 |
| 2020-09-09 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 2,216 | $62.02 |
| 2020-08-17 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 11,783 | $61.79 |
| 2020-08-17 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 3,217 | $62.34 |
| 2020-08-13 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 34,904 | $61.47 |
| 2020-08-12 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 113,500 | $60.82 |
| 2020-08-11 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 購入 | 8,180 | $10.34 |
| 2020-08-11 | RIKER, LAUREN BULLARO | Vice President, Finance | ストックオプション | 売却 | 8,180 | $0.00 |
| 2020-08-11 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 売却 | 8,180 | $60.50 |
| 2020-08-11 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 46,151 | $61.90 |
| 2020-08-11 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 60,621 | $60.87 |
| 2020-08-03 | LARANJEIRA, CHARLES ANTHONY | SVP, Technical Operations | 普通株式 | 売却 | 2,500 | $0.00 |
| 2020-08-03 | LARANJEIRA, CHARLES ANTHONY | SVP, Technical Operations | 普通株式 | 購入 | 2,500 | $44.10 |
| 2020-08-03 | LARANJEIRA, CHARLES ANTHONY | SVP, Technical Operations | 普通株式 | 売却 | 2,500 | $52.68 |
| 2020-07-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 12,000 | $56.88 |
| 2020-06-29 | LARANJEIRA, CHARLES ANTHONY | SVP, Technical Operations | 普通株式 | 購入 | 7,500 | $43.54 |
| 2020-06-29 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 売却 | 2,000 | $50.34 |
| 2020-06-29 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 売却 | 2,000 | $49.34 |
| 2020-06-29 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 売却 | 2,000 | $48.72 |
| 2020-06-29 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 購入 | 6,000 | $10.34 |
| 2020-06-29 | LARANJEIRA, CHARLES ANTHONY | SVP, Technical Operations | ストックオプション | 売却 | 30,000 | $0.00 |
| 2020-06-29 | LARANJEIRA, CHARLES ANTHONY | SVP, Technical Operations | ストックオプション | 売却 | 7,500 | $0.00 |
| 2020-06-29 | LARANJEIRA, CHARLES ANTHONY | SVP, Technical Operations | ストックオプション | 売却 | 15,000 | $0.00 |
| 2020-06-29 | LARANJEIRA, CHARLES ANTHONY | SVP, Technical Operations | ストックオプション | 売却 | 3,750 | $0.00 |
| 2020-06-29 | LARANJEIRA, CHARLES ANTHONY | SVP, Technical Operations | 普通株式 | 売却 | 1,778 | $52.03 |
| 2020-06-29 | LARANJEIRA, CHARLES ANTHONY | SVP, Technical Operations | 普通株式 | 売却 | 6,859 | $51.77 |
| 2020-06-29 | LARANJEIRA, CHARLES ANTHONY | SVP, Technical Operations | 普通株式 | 購入 | 30,000 | $44.10 |
| 2020-06-29 | LARANJEIRA, CHARLES ANTHONY | SVP, Technical Operations | 普通株式 | 売却 | 51,464 | $50.01 |
| 2020-06-29 | RIKER, LAUREN BULLARO | Vice President, Finance | ストックオプション | 売却 | 6,000 | $0.00 |
| 2020-06-29 | LARANJEIRA, CHARLES ANTHONY | SVP, Technical Operations | 普通株式 | 購入 | 3,750 | $37.81 |
| 2020-06-29 | LARANJEIRA, CHARLES ANTHONY | SVP, Technical Operations | 普通株式 | 購入 | 15,000 | $38.35 |
| 2020-06-09 | GREENSTREET, YVONNE | Director | ストックオプション | 購入 | 8,027 | $0.00 |
| 2020-06-09 | HASTINGS, PAUL J | Director | ストックオプション | 購入 | 8,027 | $0.00 |
| 2020-06-09 | HASTINGS, PAUL J | Director | 普通株式 | 購入 | 1,260 | $0.00 |
| 2020-06-09 | KRONENFELD, MARK A. | Director | ストックオプション | 購入 | 8,027 | $0.00 |
| 2020-06-09 | KRONENFELD, MARK A. | Director | 普通株式 | 購入 | 1,260 | $0.00 |
| 2020-06-09 | REINHARDT, MAX | President | ストックオプション | 購入 | 35,000 | $0.00 |
| 2020-06-09 | REINHARDT, MAX | President | 普通株式 | 購入 | 14,000 | $0.00 |
| 2020-06-09 | REINHART, CHARLES A. III | Chief Financial Officer | ストックオプション | 購入 | 31,500 | $0.00 |
| 2020-06-09 | REINHART, CHARLES A. III | Chief Financial Officer | 普通株式 | 購入 | 12,600 | $0.00 |
| 2020-06-09 | RIKER, LAUREN BULLARO | Vice President, Finance | ストックオプション | 購入 | 12,000 | $0.00 |
| 2020-06-09 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 購入 | 4,800 | $0.00 |
| 2020-06-09 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 購入 | 275,000 | $0.00 |
| 2020-06-09 | LONGENECKER, JOHN P PHD | Director | ストックオプション | 購入 | 8,027 | $0.00 |
| 2020-06-09 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 購入 | 1,260 | $0.00 |
| 2020-06-09 | PACE, GARY W | Director | ストックオプション | 購入 | 8,027 | $0.00 |
| 2020-06-09 | PACE, GARY W | Director | 普通株式 | 購入 | 1,260 | $0.00 |
| 2020-06-09 | LARANJEIRA, CHARLES ANTHONY | SVP, Technical Operations | ストックオプション | 購入 | 35,000 | $0.00 |
| 2020-06-09 | FROIMSON, MARK | Director | 普通株式 | 購入 | 1,260 | $0.00 |
| 2020-06-09 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 33,300 | $0.00 |
| 2020-06-09 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | ストックオプション | 購入 | 35,000 | $0.00 |
| 2020-06-09 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 購入 | 14,000 | $0.00 |
| 2020-06-09 | WINSTON, ROY | Chief Clinical Officer | ストックオプション | 購入 | 35,000 | $0.00 |
| 2020-06-09 | WINSTON, ROY | Chief Clinical Officer | 普通株式 | 購入 | 14,000 | $0.00 |
| 2020-06-09 | MCLOUGHLIN, DENNIS | Chief Commercial Officer | 普通株式 | 購入 | 14,000 | $0.00 |
| 2020-06-09 | MCLOUGHLIN, DENNIS | Chief Commercial Officer | ストックオプション | 購入 | 35,000 | $0.00 |
| 2020-06-09 | LARANJEIRA, CHARLES ANTHONY | SVP, Technical Operations | 普通株式 | 購入 | 14,000 | $0.00 |
| 2020-06-09 | BREGE, LAURA | Director | ストックオプション | 購入 | 8,027 | $0.00 |
| 2020-06-09 | BREGE, LAURA | Director | 普通株式 | 購入 | 1,260 | $0.00 |
| 2020-06-09 | CHRISTIE, CHRISTOPHER | Director | ストックオプション | 購入 | 8,027 | $0.00 |
| 2020-06-09 | CHRISTIE, CHRISTOPHER | Director | 普通株式 | 購入 | 1,260 | $0.00 |
| 2020-06-09 | FROIMSON, MARK | Director | ストックオプション | 購入 | 8,027 | $0.00 |
| 2020-06-09 | GREENSTREET, YVONNE | Director | 普通株式 | 購入 | 1,260 | $0.00 |
| 2020-06-08 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 1,721 | $48.49 |
| 2020-06-08 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 15,390 | $48.08 |
| 2020-06-05 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 売却 | 5,904 | $48.61 |
| 2020-06-05 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 売却 | 1,752 | $48.37 |
| 2020-06-05 | BREGE, LAURA | Director | 普通株式 | 売却 | 2,100 | $48.70 |
| 2020-06-04 | MCLOUGHLIN, DENNIS | Chief Commercial Officer | 普通株式 | 売却 | 1,447 | $46.33 |
| 2020-06-04 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 売却 | 2,402 | $46.33 |
| 2020-06-04 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 14,314 | $46.33 |
| 2020-06-04 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 売却 | 879 | $46.33 |
| 2020-06-04 | HASTINGS, PAUL J | Director | 普通株式 | 売却 | 2,025 | $47.46 |
| 2020-06-04 | LARANJEIRA, CHARLES ANTHONY | SVP, Technical Operations | 普通株式 | 売却 | 863 | $46.33 |
| 2020-06-04 | REINHART, CHARLES A. III | Chief Financial Officer | 普通株式 | 売却 | 1,489 | $46.33 |
| 2020-06-02 | MANNING, DONALD C. | Chief Medical Officer | ストックオプション | 購入 | 71,300 | $0.00 |
| 2020-06-02 | MANNING, DONALD C. | Chief Medical Officer | 普通株式 | 購入 | 28,500 | $0.00 |
| 2020-05-21 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 売却 | 2,000 | $45.26 |
| 2020-05-21 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 購入 | 2,000 | $10.34 |
| 2020-05-21 | RIKER, LAUREN BULLARO | Vice President, Finance | ストックオプション | 売却 | 2,000 | $0.00 |
| 2020-05-19 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 購入 | 2,000 | $10.34 |
| 2020-05-19 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 売却 | 2,000 | $42.81 |
| 2020-05-19 | RIKER, LAUREN BULLARO | Vice President, Finance | ストックオプション | 売却 | 2,000 | $0.00 |
| 2020-03-12 | PACE, GARY W | Director | 普通株式 | 購入 | 7,438 | $1.61 |
| 2020-03-12 | LONGENECKER, JOHN P PHD | Director | ストックオプション | 売却 | 3,736 | $0.00 |
| 2020-03-12 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 購入 | 3,736 | $1.61 |
| 2020-03-12 | PACE, GARY W | Director | 普通株式 | 購入 | 4,649 | $1.61 |
| 2020-03-12 | PACE, GARY W | Director | ストックオプション | 売却 | 4,649 | $0.00 |
| 2020-03-12 | PACE, GARY W | Director | 普通株式 | 購入 | 5,000 | $13.98 |
| 2020-03-12 | PACE, GARY W | Director | ストックオプション | 売却 | 7,438 | $0.00 |
| 2020-03-12 | PACE, GARY W | Director | ストックオプション | 売却 | 5,000 | $0.00 |
| 2020-03-11 | WINSTON, ROY | Chief Clinical Officer | 普通株式 | 購入 | 2,500 | $36.50 |
| 2020-02-21 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 16,356 | $0.00 |
| 2020-02-21 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 19,500 | $0.00 |
| 2020-02-21 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 16,356 | $5.49 |
| 2020-02-21 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 19,500 | $1.61 |
| 2020-02-10 | RIKER, LAUREN BULLARO | Vice President, Finance | ストックオプション | 売却 | 3,000 | $0.00 |
| 2020-02-10 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 売却 | 1,000 | $48.81 |
| 2020-02-10 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 売却 | 1,000 | $49.81 |
| 2020-02-10 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 売却 | 1,000 | $47.81 |
| 2020-02-10 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 購入 | 3,000 | $10.81 |
| 2020-02-07 | RIKER, LAUREN BULLARO | Vice President, Finance | ストックオプション | 売却 | 170 | $0.00 |
| 2020-02-07 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 購入 | 170 | $10.81 |
| 2020-02-07 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 売却 | 170 | $46.81 |
| 2020-02-06 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 購入 | 830 | $10.81 |
| 2020-02-06 | RIKER, LAUREN BULLARO | Vice President, Finance | ストックオプション | 売却 | 830 | $0.00 |
| 2020-02-06 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 売却 | 830 | $46.81 |
| 2020-01-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 25,000 | $10.81 |
| 2020-01-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 23,025 | $42.61 |
| 2020-01-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 1,975 | $43.48 |
| 2020-01-15 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 25,000 | $0.00 |
| 2019-12-26 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 10,000 | $0.00 |
| 2019-12-26 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 10,000 | $5.49 |
| 2019-12-26 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 10,000 | $1.61 |
| 2019-12-23 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 売却 | 1,000 | $45.92 |
| 2019-12-23 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 購入 | 1,000 | $10.81 |
| 2019-12-23 | RIKER, LAUREN BULLARO | Vice President, Finance | ストックオプション | 売却 | 1,000 | $0.00 |
| 2019-12-16 | MCLOUGHLIN, DENNIS | Chief Commercial Officer | 普通株式 | 売却 | 3,671 | $45.79 |
| 2019-12-16 | FROIMSON, MARK | Director | 普通株式 | 売却 | 300 | $0.00 |
| 2019-12-02 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 購入 | 3,128 | $1.61 |
| 2019-12-02 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 購入 | 872 | $1.61 |
| 2019-12-02 | LONGENECKER, JOHN P PHD | Director | ストックオプション | 売却 | 872 | $0.00 |
| 2019-12-02 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 売却 | 1,300 | $46.13 |
| 2019-12-02 | LONGENECKER, JOHN P PHD | Director | ストックオプション | 売却 | 3,128 | $0.00 |
| 2019-11-20 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 購入 | 1,000 | $10.81 |
| 2019-11-20 | RIKER, LAUREN BULLARO | Vice President, Finance | ストックオプション | 売却 | 1,000 | $0.00 |
| 2019-11-20 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 売却 | 1,176 | $44.14 |
| 2019-11-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 25,000 | $10.81 |
| 2019-11-15 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 25,000 | $0.00 |
| 2019-11-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 25,000 | $42.81 |
| 2019-11-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 45,000 | $42.81 |
| 2019-11-13 | ELLIS, RONALD J. JR. | Director, 10% Owner | 普通株式 | 売却 | 14,329,052 | $0.00 |
| 2019-11-13 | ELLIS, RONALD J. JR. | Director, 10% Owner | 普通株式 | 購入 | 580,357 | $ |
| 2019-11-11 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 売却 | 5,000 | $43.59 |
| 2019-11-11 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 購入 | 4,820 | $10.34 |
| 2019-11-11 | RIKER, LAUREN BULLARO | Vice President, Finance | ストックオプション | 売却 | 180 | $0.00 |
| 2019-11-11 | RIKER, LAUREN BULLARO | Vice President, Finance | ストックオプション | 売却 | 4,820 | $0.00 |
| 2019-11-11 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 購入 | 180 | $10.81 |
| 2019-11-08 | SCRANTON, RICHARD | Chief Scientific Officer | 普通株式 | 売却 | 19,448 | $45.00 |
| 2019-11-08 | SCRANTON, RICHARD | Chief Scientific Officer | ストックオプション | 売却 | 4,750 | $0.00 |
| 2019-11-08 | SCRANTON, RICHARD | Chief Scientific Officer | 普通株式 | 購入 | 4,750 | $25.37 |
| 2019-11-08 | SCRANTON, RICHARD | Chief Scientific Officer | 普通株式 | 購入 | 14,698 | $10.81 |
| 2019-11-08 | SCRANTON, RICHARD | Chief Scientific Officer | ストックオプション | 売却 | 14,698 | $0.00 |
| 2019-10-02 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 7,000 | $1.61 |
| 2019-10-02 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 10,000 | $5.49 |
| 2019-10-02 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 7,000 | $0.00 |
| 2019-10-02 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 10,000 | $0.00 |
| 2019-09-18 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 7,500 | $0.00 |
| 2019-09-18 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 7,500 | $1.61 |
| 2019-09-18 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 6,500 | $5.49 |
| 2019-09-18 | CHRISTIE, CHRISTOPHER | Director | ストックオプション | 購入 | 19,919 | $0.00 |
| 2019-09-18 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 6,500 | $0.00 |
| 2019-08-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 12,849 | $10.81 |
| 2019-08-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 10,458 | $39.05 |
| 2019-08-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 2,391 | $39.61 |
| 2019-08-15 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 12,849 | $0.00 |
| 2019-08-14 | WILLIAMS, KRISTEN MARIE | Chief Administrative Officer | 普通株式 | 売却 | 6,252 | $39.49 |
| 2019-07-08 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 12,415 | $42.85 |
| 2019-07-08 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 700 | $43.42 |
| 2019-07-02 | REINHARDT, MAX | President | ストックオプション | 購入 | 200,000 | $0.00 |
| 2019-06-11 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 15,000 | $1.61 |
| 2019-06-11 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 9,000 | $5.49 |
| 2019-06-11 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 9,000 | $0.00 |
| 2019-06-11 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 15,000 | $0.00 |
| 2019-06-10 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 売却 | 2,126 | $44.28 |
| 2019-06-05 | HASTINGS, PAUL J | Director | 普通株式 | 購入 | 4,134 | $0.00 |
| 2019-06-05 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 23,700 | $0.00 |
| 2019-06-05 | SCRANTON, RICHARD | Chief Scientific Officer | 普通株式 | 売却 | 4,114 | $43.50 |
| 2019-06-05 | SCRANTON, RICHARD | Chief Scientific Officer | 普通株式 | 購入 | 5,000 | $0.00 |
| 2019-06-05 | WINSTON, ROY | Chief Clinical Officer | 普通株式 | 購入 | 5,600 | $0.00 |
| 2019-06-05 | WINSTON, ROY | Chief Clinical Officer | ストックオプション | 購入 | 33,800 | $0.00 |
| 2019-06-05 | WILLIAMS, KRISTEN MARIE | CAO and General Counsel | 普通株式 | 購入 | 5,600 | $0.00 |
| 2019-06-05 | WILLIAMS, KRISTEN MARIE | CAO and General Counsel | ストックオプション | 購入 | 33,800 | $0.00 |
| 2019-06-05 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 購入 | 142,100 | $0.00 |
| 2019-06-05 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 購入 | 4,134 | $0.00 |
| 2019-06-05 | LONGENECKER, JOHN P PHD | Director | ストックオプション | 購入 | 8,437 | $0.00 |
| 2019-06-05 | LARANJEIRA, CHARLES ANTHONY | SVP, Technical Operations | 普通株式 | 購入 | 5,000 | $0.00 |
| 2019-06-05 | LARANJEIRA, CHARLES ANTHONY | SVP, Technical Operations | ストックオプション | 購入 | 30,000 | $0.00 |
| 2019-06-05 | KRONENFELD, MARK A. | Director | 普通株式 | 購入 | 4,134 | $0.00 |
| 2019-06-05 | KRONENFELD, MARK A. | Director | ストックオプション | 購入 | 8,437 | $0.00 |
| 2019-06-05 | HASTINGS, PAUL J | Director | ストックオプション | 購入 | 8,437 | $0.00 |
| 2019-06-05 | GREENSTREET, YVONNE | Director | 普通株式 | 購入 | 4,134 | $0.00 |
| 2019-06-05 | GREENSTREET, YVONNE | Director | ストックオプション | 購入 | 8,437 | $0.00 |
| 2019-06-05 | FROIMSON, MARK | Director | 普通株式 | 購入 | 4,134 | $0.00 |
| 2019-06-05 | FROIMSON, MARK | Director | ストックオプション | 購入 | 8,437 | $0.00 |
| 2019-06-05 | BREGE, LAURA | Director | 普通株式 | 購入 | 4,134 | $0.00 |
| 2019-06-05 | BREGE, LAURA | Director | ストックオプション | 購入 | 8,437 | $0.00 |
| 2019-06-05 | SCRANTON, RICHARD | Chief Scientific Officer | ストックオプション | 購入 | 30,000 | $0.00 |
| 2019-06-05 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 購入 | 1,900 | $0.00 |
| 2019-06-05 | RIKER, LAUREN BULLARO | Vice President, Finance | ストックオプション | 購入 | 11,200 | $0.00 |
| 2019-06-05 | REINHART, CHARLES A. III | Chief Financial Officer | 普通株式 | 購入 | 4,400 | $0.00 |
| 2019-06-05 | REINHART, CHARLES A. III | Chief Financial Officer | ストックオプション | 購入 | 26,300 | $0.00 |
| 2019-06-05 | PACE, GARY W | Director | 普通株式 | 購入 | 4,134 | $0.00 |
| 2019-06-05 | PACE, GARY W | Director | ストックオプション | 購入 | 8,437 | $0.00 |
| 2019-06-05 | MCLOUGHLIN, DENNIS | Chief Commercial Officer | 普通株式 | 購入 | 5,600 | $0.00 |
| 2019-06-05 | MCLOUGHLIN, DENNIS | Chief Commercial Officer | ストックオプション | 購入 | 33,800 | $0.00 |
| 2019-06-04 | SCRANTON, RICHARD | Chief Scientific Officer | 普通株式 | 売却 | 2,074 | $42.91 |
| 2019-06-04 | WINSTON, ROY | Chief Clinical Officer | 普通株式 | 売却 | 722 | $42.91 |
| 2019-06-04 | MCLOUGHLIN, DENNIS | Chief Commercial Officer | 普通株式 | 売却 | 1,099 | $42.91 |
| 2019-06-04 | HASTINGS, PAUL J | Director | 普通株式 | 売却 | 782 | $42.66 |
| 2019-06-04 | LARANJEIRA, CHARLES ANTHONY | SVP, Technical Operations | 普通株式 | 売却 | 430 | $42.91 |
| 2019-06-04 | REINHART, CHARLES A. III | Chief Financial Officer | 普通株式 | 売却 | 1,106 | $42.91 |
| 2019-06-04 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 12,385 | $42.91 |
| 2019-06-04 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 売却 | 967 | $42.91 |
| 2019-06-04 | WILLIAMS, KRISTEN MARIE | CAO and General Counsel | 普通株式 | 売却 | 2,529 | $42.91 |
| 2019-06-04 | SCRANTON, RICHARD | Chief Scientific Officer | 普通株式 | 売却 | 2,852 | $42.66 |
| 2019-06-03 | SCRANTON, RICHARD | Chief Scientific Officer | 普通株式 | 売却 | 15,510 | $43.21 |
| 2019-06-03 | SCRANTON, RICHARD | Chief Scientific Officer | 普通株式 | 購入 | 12,500 | $10.81 |
| 2019-06-03 | SCRANTON, RICHARD | Chief Scientific Officer | 普通株式 | 購入 | 3,010 | $10.52 |
| 2019-06-03 | SCRANTON, RICHARD | Chief Scientific Officer | ストックオプション | 売却 | 3,010 | $0.00 |
| 2019-06-03 | SCRANTON, RICHARD | Chief Scientific Officer | ストックオプション | 売却 | 12,500 | $0.00 |
| 2019-03-06 | KRONENFELD, MARK A. | Director | 普通株式 | 購入 | 700 | $38.72 |
| 2019-03-06 | KRONENFELD, MARK A. | Director | 普通株式 | 購入 | 1,000 | $39.14 |
| 2018-12-18 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 6,000 | $1.61 |
| 2018-12-18 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 6,000 | $0.00 |
| 2018-12-18 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 6,000 | $5.49 |
| 2018-12-13 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 8,720 | $46.18 |
| 2018-12-12 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 5,807 | $47.84 |
| 2018-11-19 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 990 | $47.08 |
| 2018-11-19 | PACE, GARY W | Director | 普通株式 | 購入 | 4,500 | $46.18 |
| 2018-11-16 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 3,500 | $47.07 |
| 2018-11-16 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 22,100 | $46.79 |
| 2018-11-15 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 26,089 | $47.63 |
| 2018-11-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 4,558 | $47.70 |
| 2018-11-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 10,442 | $47.25 |
| 2018-11-15 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 18,809 | $47.64 |
| 2018-11-12 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 5,478 | $49.83 |
| 2018-11-09 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 906 | $50.23 |
| 2018-11-08 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 57,339 | $51.13 |
| 2018-11-07 | PACE, GARY W | Director | 普通株式 | 購入 | 4,000 | $51.29 |
| 2018-11-02 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 購入 | 1,000 | $10.34 |
| 2018-11-02 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 売却 | 1,000 | $54.35 |
| 2018-11-02 | RIKER, LAUREN BULLARO | Vice President, Finance | ストックオプション | 売却 | 1,000 | $0.00 |
| 2018-10-11 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 11,810 | $0.00 |
| 2018-10-11 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 15,000 | $5.49 |
| 2018-10-11 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 15,000 | $0.00 |
| 2018-10-11 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 18,190 | $0.00 |
| 2018-10-11 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 11,810 | $1.61 |
| 2018-10-11 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 18,190 | $1.61 |
| 2018-09-24 | RIKER, LAUREN BULLARO | Vice President, Finance | ストックオプション | 売却 | 1,000 | $0.00 |
| 2018-09-24 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 購入 | 1,000 | $10.34 |
| 2018-09-24 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 売却 | 1,000 | $50.70 |
| 2018-09-05 | MCLOUGHLIN, DENNIS | Chief Commercial Officer | ストックオプション | 購入 | 20,000 | $0.00 |
| 2018-08-28 | KRONENFELD, MARK A. | Director | 普通株式 | 購入 | 1,000 | $44.61 |
| 2018-08-22 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 売却 | 1,667 | $44.48 |
| 2018-08-15 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 13,481 | $0.00 |
| 2018-08-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 610 | $5.49 |
| 2018-08-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 13,481 | $10.81 |
| 2018-08-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 21,198 | $47.11 |
| 2018-08-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 11,864 | $47.69 |
| 2018-08-15 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 610 | $0.00 |
| 2018-08-14 | WILLIAMS, KRISTEN MARIE | CAO and General Counsel | 普通株式 | 売却 | 4,773 | $47.04 |
| 2018-06-13 | FROIMSON, MARK | Director | 普通株式 | 購入 | 782 | $0.00 |
| 2018-06-13 | GREENSTREET, YVONNE | Director | ストックオプション | 購入 | 4,693 | $0.00 |
| 2018-06-13 | HASTINGS, PAUL J | Director | 普通株式 | 購入 | 782 | $0.00 |
| 2018-06-13 | KRONENFELD, MARK A. | Director | ストックオプション | 購入 | 4,693 | $0.00 |
| 2018-06-13 | KRONENFELD, MARK A. | Director | 普通株式 | 購入 | 782 | $0.00 |
| 2018-06-13 | LONGENECKER, JOHN P PHD | Director | ストックオプション | 購入 | 4,693 | $0.00 |
| 2018-06-13 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 購入 | 782 | $0.00 |
| 2018-06-13 | PACE, GARY W | Director | ストックオプション | 購入 | 4,693 | $0.00 |
| 2018-06-13 | RIKER, LAUREN BULLARO | Vice President, Finance | ストックオプション | 購入 | 25,000 | $0.00 |
| 2018-06-13 | LARANJEIRA, CHARLES ANTHONY | SVP, Technical Operations | ストックオプション | 購入 | 30,000 | $0.00 |
| 2018-06-13 | PACE, GARY W | Director | 普通株式 | 購入 | 782 | $0.00 |
| 2018-06-13 | WILLIAMS, KRISTEN MARIE | CAO and General Counsel | 普通株式 | 購入 | 7,875 | $0.00 |
| 2018-06-13 | WILLIAMS, KRISTEN MARIE | CAO and General Counsel | ストックオプション | 購入 | 47,250 | $0.00 |
| 2018-06-13 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 28,375 | $0.00 |
| 2018-06-13 | FROIMSON, MARK | Director | ストックオプション | 購入 | 4,693 | $0.00 |
| 2018-06-13 | BREGE, LAURA | Director | 普通株式 | 購入 | 782 | $0.00 |
| 2018-06-13 | BREGE, LAURA | Director | ストックオプション | 購入 | 4,693 | $0.00 |
| 2018-06-13 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 購入 | 170,250 | $0.00 |
| 2018-06-13 | SCRANTON, RICHARD | Chief Scientific Officer | 普通株式 | 購入 | 7,875 | $0.00 |
| 2018-06-13 | SCRANTON, RICHARD | Chief Scientific Officer | ストックオプション | 購入 | 47,250 | $0.00 |
| 2018-06-13 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 購入 | 2,500 | $0.00 |
| 2018-06-13 | GREENSTREET, YVONNE | Director | 普通株式 | 購入 | 782 | $0.00 |
| 2018-06-13 | HASTINGS, PAUL J | Director | ストックオプション | 購入 | 4,693 | $0.00 |
| 2018-06-13 | LARANJEIRA, CHARLES ANTHONY | SVP, Technical Operations | 普通株式 | 購入 | 5,000 | $0.00 |
| 2018-06-13 | REINHART, CHARLES A. III | Chief Financial Officer | ストックオプション | 購入 | 30,000 | $0.00 |
| 2018-06-13 | REINHART, CHARLES A. III | Chief Financial Officer | 普通株式 | 購入 | 5,000 | $0.00 |
| 2018-06-07 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 2,600 | $37.53 |
| 2018-06-07 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 7,191 | $36.63 |
| 2018-06-06 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 8,615 | $35.61 |
| 2018-06-04 | HASTINGS, PAUL J | Director | 普通株式 | 売却 | 771 | $33.90 |
| 2018-06-04 | SCRANTON, RICHARD | Chief Scientific Officer | 普通株式 | 売却 | 1,367 | $33.02 |
| 2018-06-04 | REINHART, CHARLES A. III | Chief Financial Officer | 普通株式 | 売却 | 708 | $33.02 |
| 2018-06-04 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 売却 | 801 | $33.02 |
| 2018-06-04 | WEILAND, ROBERT J. | Chief Commercial Officer | 普通株式 | 売却 | 373 | $33.02 |
| 2018-06-04 | WILLIAMS, KRISTEN MARIE | CAO and General Counsel | 普通株式 | 売却 | 2,040 | $33.02 |
| 2018-05-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 21,106 | $33.69 |
| 2018-05-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 15,000 | $5.49 |
| 2018-05-15 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 10,000 | $0.00 |
| 2018-05-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 3,894 | $34.34 |
| 2018-05-15 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 15,000 | $0.00 |
| 2018-05-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 10,000 | $10.81 |
| 2018-05-02 | SCRANTON, RICHARD | Chief Scientific Officer | ストックオプション | 購入 | 20,000 | $0.00 |
| 2018-01-10 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 28,885 | $0.00 |
| 2018-01-10 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 28,885 | $1.61 |
| 2018-01-10 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 23,372 | $39.96 |
| 2018-01-10 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 4,628 | $41.03 |
| 2018-01-10 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 885 | $41.97 |
| 2018-01-03 | BRAUNSTEIN, SCOTT | Chief Operating Officer | ストックオプション | 購入 | 60,000 | $0.00 |
| 2017-12-15 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 売却 | 340 | $43.70 |
| 2017-11-20 | JONES, JAMES B | SVP & Chief Medical Officer | 普通株式 | 売却 | 850 | $41.11 |
| 2017-11-17 | WILLIAMS, KRISTEN MARIE | CAO and General Counsel | ストックオプション | 売却 | 7,857 | $0.00 |
| 2017-11-17 | WILLIAMS, KRISTEN MARIE | CAO and General Counsel | 普通株式 | 購入 | 7,857 | $25.37 |
| 2017-11-17 | WILLIAMS, KRISTEN MARIE | CAO and General Counsel | 普通株式 | 売却 | 7,857 | $40.00 |
| 2017-11-16 | WILLIAMS, KRISTEN MARIE | CAO and General Counsel | ストックオプション | 売却 | 2,143 | $0.00 |
| 2017-11-16 | WILLIAMS, KRISTEN MARIE | CAO and General Counsel | 普通株式 | 購入 | 2,143 | $25.37 |
| 2017-11-16 | WILLIAMS, KRISTEN MARIE | CAO and General Counsel | 普通株式 | 売却 | 2,143 | $40.01 |
| 2017-11-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 28,885 | $1.61 |
| 2017-11-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 1,900 | $38.97 |
| 2017-11-15 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 28,885 | $0.00 |
| 2017-11-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 56,985 | $38.32 |
| 2017-11-10 | KRONENFELD, MARK A. | Director | 普通株式 | 購入 | 1,000 | $41.60 |
| 2017-08-22 | HASTINGS, PAUL J | Director | 普通株式 | 売却 | 1,044 | $36.15 |
| 2017-08-15 | WILLIAMS, KRISTEN MARIE | CAO and General Counsel | 普通株式 | 売却 | 3,461 | $36.75 |
| 2017-08-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 28,885 | $1.61 |
| 2017-08-15 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 28,885 | $0.00 |
| 2017-08-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 28,885 | $36.37 |
| 2017-08-08 | FROIMSON, MARK | Director | 普通株式 | 購入 | 100 | $37.13 |
| 2017-07-24 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 15,000 | $0.00 |
| 2017-07-24 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 15,000 | $1.61 |
| 2017-06-23 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 15,000 | $0.00 |
| 2017-06-23 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 15,000 | $1.61 |
| 2017-06-14 | SCRANTON, RICHARD | Chief Scientific Officer | 普通株式 | 購入 | 8,750 | $0.00 |
| 2017-06-14 | BRAUNSTEIN, SCOTT | SVP, Strategy & Corp. Dev. | ストックオプション | 購入 | 22,000 | $0.00 |
| 2017-06-14 | GREENSTREET, YVONNE | Director | 普通株式 | 購入 | 1,357 | $0.00 |
| 2017-06-14 | HASTINGS, PAUL J | Director | ストックオプション | 購入 | 2,714 | $0.00 |
| 2017-06-14 | HASTINGS, PAUL J | Director | 普通株式 | 購入 | 1,357 | $0.00 |
| 2017-06-14 | KRONENFELD, MARK A. | Director | ストックオプション | 購入 | 2,714 | $0.00 |
| 2017-06-14 | BREGE, LAURA | Director | 普通株式 | 購入 | 1,357 | $0.00 |
| 2017-06-14 | FROIMSON, MARK | Director | ストックオプション | 購入 | 8,144 | $0.00 |
| 2017-06-14 | GREENSTREET, YVONNE | Director | ストックオプション | 購入 | 2,714 | $0.00 |
| 2017-06-14 | KRONENFELD, MARK A. | Director | 普通株式 | 購入 | 1,357 | $0.00 |
| 2017-06-14 | LONGENECKER, JOHN P PHD | Director | ストックオプション | 購入 | 2,714 | $0.00 |
| 2017-06-14 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 購入 | 1,357 | $0.00 |
| 2017-06-14 | PACE, GARY W | Director | ストックオプション | 購入 | 2,714 | $0.00 |
| 2017-06-14 | PACE, GARY W | Director | 普通株式 | 購入 | 1,357 | $0.00 |
| 2017-06-14 | WINGER, DENNIS L | Director | ストックオプション | 購入 | 2,714 | $0.00 |
| 2017-06-14 | WINGER, DENNIS L | Director | 普通株式 | 購入 | 1,357 | $0.00 |
| 2017-06-14 | BREGE, LAURA | Director | ストックオプション | 購入 | 2,714 | $0.00 |
| 2017-06-14 | WILLIAMS, KRISTEN MARIE | CAO and General Counsel | 普通株式 | 購入 | 11,000 | $0.00 |
| 2017-06-14 | WILLIAMS, KRISTEN MARIE | CAO and General Counsel | ストックオプション | 購入 | 22,000 | $0.00 |
| 2017-06-14 | WEILAND, ROBERT J. | Chief Commercial Officer | 普通株式 | 購入 | 4,500 | $0.00 |
| 2017-06-14 | WEILAND, ROBERT J. | Chief Commercial Officer | ストックオプション | 購入 | 9,000 | $0.00 |
| 2017-06-14 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 40,500 | $0.00 |
| 2017-06-14 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 購入 | 81,000 | $0.00 |
| 2017-06-14 | SCRANTON, RICHARD | Chief Scientific Officer | ストックオプション | 購入 | 17,500 | $0.00 |
| 2017-06-14 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 購入 | 3,000 | $0.00 |
| 2017-06-14 | RIKER, LAUREN BULLARO | Vice President, Finance | ストックオプション | 購入 | 6,000 | $0.00 |
| 2017-06-14 | REINHART, CHARLES A. III | Chief Financial Officer | 普通株式 | 購入 | 8,750 | $0.00 |
| 2017-06-14 | REINHART, CHARLES A. III | Chief Financial Officer | ストックオプション | 購入 | 17,500 | $0.00 |
| 2017-06-14 | JONES, JAMES B | SVP & Chief Medical Officer | 普通株式 | 購入 | 7,500 | $0.00 |
| 2017-06-14 | JONES, JAMES B | SVP & Chief Medical Officer | ストックオプション | 購入 | 15,000 | $0.00 |
| 2017-06-14 | BRAUNSTEIN, SCOTT | SVP, Strategy & Corp. Dev. | 普通株式 | 購入 | 11,000 | $0.00 |
| 2017-06-07 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 売却 | 1,119 | $44.37 |
| 2017-06-05 | SCIBETTA, JAMES S | President | 普通株式 | 売却 | 1,966 | $43.32 |
| 2017-06-05 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 売却 | 601 | $43.32 |
| 2017-06-05 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 4,311 | $43.32 |
| 2017-06-05 | BRAUNSTEIN, SCOTT | SVP, Strategy & Corp. Dev. | 普通株式 | 売却 | 768 | $43.32 |
| 2017-06-05 | JONES, JAMES B | SVP & Chief Medical Officer | 普通株式 | 売却 | 767 | $43.32 |
| 2017-06-05 | WILLIAMS, KRISTEN MARIE | CAO and General Counsel | 普通株式 | 売却 | 1,877 | $43.32 |
| 2017-06-02 | BRAUNSTEIN, SCOTT | SVP, Strategy & Corp. Dev. | ストックオプション | 購入 | 10,000 | $0.00 |
| 2017-05-15 | WILLIAMS, KRISTEN MARIE | CAO and General Counsel | 普通株式 | 購入 | 5,937 | $10.52 |
| 2017-05-15 | WILLIAMS, KRISTEN MARIE | CAO and General Counsel | 普通株式 | 購入 | 3,125 | $9.25 |
| 2017-05-15 | SCIBETTA, JAMES S | President | 普通株式 | 購入 | 20,000 | $5.49 |
| 2017-05-15 | SCIBETTA, JAMES S | President | ストックオプション | 売却 | 20,000 | $0.00 |
| 2017-05-15 | SCIBETTA, JAMES S | President | 普通株式 | 売却 | 20,000 | $51.20 |
| 2017-05-15 | WILLIAMS, KRISTEN MARIE | CAO and General Counsel | ストックオプション | 売却 | 5,937 | $0.00 |
| 2017-05-15 | WILLIAMS, KRISTEN MARIE | CAO and General Counsel | 普通株式 | 購入 | 11,979 | $10.81 |
| 2017-05-15 | WILLIAMS, KRISTEN MARIE | CAO and General Counsel | ストックオプション | 売却 | 11,979 | $0.00 |
| 2017-05-15 | WILLIAMS, KRISTEN MARIE | CAO and General Counsel | ストックオプション | 売却 | 3,125 | $0.00 |
| 2017-05-15 | WILLIAMS, KRISTEN MARIE | CAO and General Counsel | 普通株式 | 売却 | 21,041 | $50.86 |
| 2017-01-17 | SCIBETTA, JAMES S | President | 普通株式 | 売却 | 4,997 | $38.97 |
| 2017-01-17 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 15,000 | $0.00 |
| 2017-01-17 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 1,300 | $38.81 |
| 2017-01-17 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 13,700 | $38.37 |
| 2017-01-17 | SCIBETTA, JAMES S | President | 普通株式 | 購入 | 2,373 | $1.61 |
| 2017-01-17 | SCIBETTA, JAMES S | President | 普通株式 | 購入 | 17,627 | $5.49 |
| 2017-01-17 | SCIBETTA, JAMES S | President | 普通株式 | 売却 | 15,003 | $38.39 |
| 2017-01-17 | SCIBETTA, JAMES S | President | ストックオプション | 売却 | 2,373 | $0.00 |
| 2017-01-17 | SCIBETTA, JAMES S | President | ストックオプション | 売却 | 17,627 | $0.00 |
| 2017-01-17 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 15,000 | $5.49 |
| 2016-12-07 | REINHART, CHARLES A. III | Chief Financial Officer | ストックオプション | 購入 | 16,000 | $0.00 |
| 2016-12-07 | WILLIAMS, KRISTEN MARIE | CAO and General Counsel | ストックオプション | 購入 | 20,000 | $0.00 |
| 2016-12-07 | WEILAND, ROBERT J. | Chief Commercial Officer | ストックオプション | 購入 | 16,000 | $0.00 |
| 2016-12-07 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 購入 | 60,000 | $0.00 |
| 2016-12-07 | SCIBETTA, JAMES S | President | ストックオプション | 購入 | 20,000 | $0.00 |
| 2016-12-07 | RIKER, LAUREN BULLARO | Vice President, Finance | ストックオプション | 購入 | 6,000 | $0.00 |
| 2016-12-07 | BRAUNSTEIN, SCOTT | SVP, Strategy & Corp. Dev. | ストックオプション | 購入 | 20,000 | $0.00 |
| 2016-12-07 | JONES, JAMES B | SVP & Chief Medical Officer | ストックオプション | 購入 | 10,000 | $0.00 |
| 2016-11-15 | SCIBETTA, JAMES S | President | ストックオプション | 売却 | 20,000 | $0.00 |
| 2016-11-15 | SCIBETTA, JAMES S | President | 普通株式 | 購入 | 20,000 | $1.61 |
| 2016-11-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 15,000 | $5.49 |
| 2016-11-15 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 15,000 | $0.00 |
| 2016-11-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 1,800 | $37.76 |
| 2016-11-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 13,200 | $37.21 |
| 2016-11-15 | SCIBETTA, JAMES S | President | 普通株式 | 売却 | 20,000 | $36.50 |
| 2016-10-05 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 30,000 | $1.61 |
| 2016-10-05 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 30,000 | $0.00 |
| 2016-08-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 15,000 | $5.49 |
| 2016-08-15 | SCIBETTA, JAMES S | President | 普通株式 | 購入 | 15,877 | $1.61 |
| 2016-08-15 | SCIBETTA, JAMES S | President | 普通株式 | 売却 | 25,000 | $45.21 |
| 2016-08-15 | SCIBETTA, JAMES S | President | ストックオプション | 売却 | 9,123 | $0.00 |
| 2016-08-15 | SCIBETTA, JAMES S | President | ストックオプション | 売却 | 15,877 | $0.00 |
| 2016-08-15 | SCIBETTA, JAMES S | President | 普通株式 | 購入 | 9,123 | $1.61 |
| 2016-08-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 15,000 | $45.32 |
| 2016-08-15 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 15,000 | $0.00 |
| 2016-06-15 | WINGER, DENNIS L | Director | ストックオプション | 購入 | 2,975 | $0.00 |
| 2016-06-15 | PACE, GARY W | Director | ストックオプション | 購入 | 2,975 | $0.00 |
| 2016-06-15 | JONES, JAMES B | SVP & Chief Medical Officer | 普通株式 | 購入 | 8,750 | $0.00 |
| 2016-06-15 | BREGE, LAURA | Director | ストックオプション | 購入 | 2,975 | $0.00 |
| 2016-06-15 | BREGE, LAURA | Director | 普通株式 | 購入 | 1,488 | $0.00 |
| 2016-06-15 | WILLIAMS, KRISTEN MARIE | CAO and General Counsel | ストックオプション | 購入 | 17,500 | $0.00 |
| 2016-06-15 | WEILAND, ROBERT J. | Chief Commercial Officer | ストックオプション | 購入 | 10,000 | $0.00 |
| 2016-06-15 | SCIBETTA, JAMES S | President & CFO | 普通株式 | 購入 | 16,250 | $0.00 |
| 2016-06-15 | JONES, JAMES B | SVP & Chief Medical Officer | ストックオプション | 購入 | 17,500 | $0.00 |
| 2016-06-15 | SCIBETTA, JAMES S | President & CFO | ストックオプション | 購入 | 32,500 | $0.00 |
| 2016-06-15 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 購入 | 3,125 | $0.00 |
| 2016-06-15 | RIKER, LAUREN BULLARO | Vice President, Finance | ストックオプション | 購入 | 6,250 | $0.00 |
| 2016-06-15 | WILLIAMS, KRISTEN MARIE | CAO and General Counsel | 普通株式 | 購入 | 8,750 | $0.00 |
| 2016-06-15 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 購入 | 1,488 | $0.00 |
| 2016-06-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 33,125 | $0.00 |
| 2016-06-15 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 購入 | 66,250 | $0.00 |
| 2016-06-15 | GREENSTREET, YVONNE | Director | 普通株式 | 購入 | 1,488 | $0.00 |
| 2016-06-15 | HASTINGS, PAUL J | Director | ストックオプション | 購入 | 2,975 | $0.00 |
| 2016-06-15 | HASTINGS, PAUL J | Director | 普通株式 | 購入 | 1,488 | $0.00 |
| 2016-06-15 | KRONENFELD, MARK A. | Director | ストックオプション | 購入 | 2,975 | $0.00 |
| 2016-06-15 | KRONENFELD, MARK A. | Director | 普通株式 | 購入 | 1,488 | $0.00 |
| 2016-06-15 | LONGENECKER, JOHN P PHD | Director | ストックオプション | 購入 | 2,975 | $0.00 |
| 2016-06-15 | GREENSTREET, YVONNE | Director | ストックオプション | 購入 | 2,975 | $0.00 |
| 2016-06-15 | BRAUNSTEIN, SCOTT | SVP, Strategy & Corp. Dev. | 普通株式 | 購入 | 8,750 | $0.00 |
| 2016-06-15 | BRAUNSTEIN, SCOTT | SVP, Strategy & Corp. Dev. | ストックオプション | 購入 | 17,500 | $0.00 |
| 2016-06-15 | WINGER, DENNIS L | Director | 普通株式 | 購入 | 1,488 | $0.00 |
| 2016-06-15 | PACE, GARY W | Director | 普通株式 | 購入 | 1,488 | $0.00 |
| 2016-06-07 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 売却 | 517 | $47.90 |
| 2016-06-07 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 売却 | 100 | $47.90 |
| 2016-06-06 | BREGE, LAURA | Director | 普通株式 | 売却 | 1,000 | $46.95 |
| 2016-06-06 | HASTINGS, PAUL J | Director | 普通株式 | 売却 | 1,136 | $46.95 |
| 2016-06-06 | WILLIAMS, KRISTEN MARIE | CAO and General Counsel | 普通株式 | 売却 | 600 | $47.20 |
| 2016-06-06 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 売却 | 321 | $47.20 |
| 2016-06-06 | KRONENFELD, MARK A. | Director | 普通株式 | 売却 | 900 | $46.95 |
| 2016-05-03 | WEILAND, ROBERT J. | Chief Commercial Officer | ストックオプション | 購入 | 40,000 | $0.00 |
| 2016-05-03 | REINHART, CHARLES A. III | Chief Financial Officer | ストックオプション | 購入 | 70,000 | $0.00 |
| 2016-04-15 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 25,000 | $0.00 |
| 2016-04-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 25,000 | $5.49 |
| 2016-04-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 18,650 | $63.97 |
| 2016-04-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 6,350 | $64.62 |
| 2016-02-17 | HASTINGS, PAUL J | Director | 普通株式 | 購入 | 1,000 | $10.81 |
| 2016-02-17 | HASTINGS, PAUL J | Director | 普通株式 | 売却 | 3,000 | $60.00 |
| 2016-02-17 | HASTINGS, PAUL J | Director | ストックオプション | 売却 | 2,000 | $0.00 |
| 2016-02-17 | HASTINGS, PAUL J | Director | ストックオプション | 売却 | 1,000 | $0.00 |
| 2016-02-17 | HASTINGS, PAUL J | Director | 普通株式 | 購入 | 2,000 | $13.98 |
| 2016-01-29 | BRAUNSTEIN, SCOTT | SVP, Strategy & Corp. Dev. | 普通株式 | 購入 | 2,000 | $58.92 |
| 2016-01-27 | JONES, JAMES B | SVP & Chief Medical Officer | 普通株式 | 購入 | 500 | $62.50 |
| 2016-01-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 4,392 | $64.46 |
| 2016-01-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 購入 | 15,000 | $1.61 |
| 2016-01-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 1,000 | $62.55 |
| 2016-01-15 | STACK, DAVID M | Director, CEO and Chairman | ストックオプション | 売却 | 15,000 | $0.00 |
| 2016-01-15 | STACK, DAVID M | Director, CEO and Chairman | 普通株式 | 売却 | 9,608 | $63.69 |
| 2016-01-12 | JONES, JAMES B | SVP & Chief Medical Officer | 普通株式 | 購入 | 1,000 | $66.00 |
| 2016-01-12 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 購入 | 300 | $66.55 |
| 2015-11-20 | HASTINGS, PAUL J | Director | 普通株式 | 購入 | 3,000 | $10.81 |
| 2015-11-20 | HASTINGS, PAUL J | Director | ストックオプション | 売却 | 3,000 | $0.00 |
| 2015-11-20 | HASTINGS, PAUL J | Director | 普通株式 | 売却 | 3,000 | $60.00 |
| 2015-11-03 | SCIBETTA, JAMES S | President & CFO | ストックオプション | 購入 | 40,000 | $0.00 |
| 2015-10-15 | STACK, DAVID M | Director, President, CEO and Chairman | ストックオプション | 売却 | 15,000 | $0.00 |
| 2015-10-15 | STACK, DAVID M | Director, President, CEO and Chairman | 普通株式 | 購入 | 15,000 | $1.61 |
| 2015-10-15 | STACK, DAVID M | Director, President, CEO and Chairman | 普通株式 | 売却 | 6,601 | $37.11 |
| 2015-10-15 | STACK, DAVID M | Director, President, CEO and Chairman | 普通株式 | 売却 | 7,799 | $37.89 |
| 2015-10-15 | STACK, DAVID M | Director, President, CEO and Chairman | 普通株式 | 売却 | 600 | $38.49 |
| 2015-09-11 | SCIBETTA, JAMES S | SVP, Chief Financial Officer | 普通株式 | 購入 | 5,000 | $61.37 |
| 2015-08-17 | JONES, JAMES B | SVP & Chief Medical Officer | ストックオプション | 購入 | 40,000 | $0.00 |
| 2015-08-17 | HASTINGS, PAUL J | Director | ストックオプション | 売却 | 3,000 | $0.00 |
| 2015-08-17 | HASTINGS, PAUL J | Director | 普通株式 | 売却 | 3,000 | $60.02 |
| 2015-08-17 | HASTINGS, PAUL J | Director | 普通株式 | 購入 | 3,000 | $10.81 |
| 2015-07-15 | STACK, DAVID M | Director, President, CEO and Chairman | 普通株式 | 売却 | 15,000 | $67.78 |
| 2015-07-15 | STACK, DAVID M | Director, President, CEO and Chairman | 普通株式 | 購入 | 15,000 | $1.61 |
| 2015-07-15 | STACK, DAVID M | Director, President, CEO and Chairman | ストックオプション | 売却 | 15,000 | $0.00 |
| 2015-07-13 | BRAUNSTEIN, SCOTT | SVP, Strategy & Corp. Dev. | ストックオプション | 購入 | 75,000 | $0.00 |
| 2015-06-03 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 購入 | 2,000 | $0.00 |
| 2015-06-03 | WILLIAMS, KRISTEN MARIE | CAO and General Counsel | ストックオプション | 購入 | 15,000 | $0.00 |
| 2015-06-03 | WILLIAMS, KRISTEN MARIE | CAO and General Counsel | 普通株式 | 購入 | 7,500 | $0.00 |
| 2015-06-03 | HASTINGS, PAUL J | Director | 普通株式 | 購入 | 2,000 | $0.00 |
| 2015-06-03 | WINGER, DENNIS L | Director | ストックオプション | 購入 | 4,000 | $0.00 |
| 2015-06-03 | PACE, GARY W | Director | 普通株式 | 購入 | 2,000 | $0.00 |
| 2015-06-03 | PACE, GARY W | Director | ストックオプション | 購入 | 4,000 | $0.00 |
| 2015-06-03 | BREGE, LAURA | Director | ストックオプション | 購入 | 4,000 | $0.00 |
| 2015-06-03 | BREGE, LAURA | Director | 普通株式 | 購入 | 2,000 | $0.00 |
| 2015-06-03 | GREENSTREET, YVONNE | Director | ストックオプション | 購入 | 4,000 | $0.00 |
| 2015-06-03 | GREENSTREET, YVONNE | Director | 普通株式 | 購入 | 2,000 | $0.00 |
| 2015-06-03 | KRONENFELD, MARK A. | Director | ストックオプション | 購入 | 4,000 | $0.00 |
| 2015-06-03 | KRONENFELD, MARK A. | Director | 普通株式 | 購入 | 2,000 | $0.00 |
| 2015-06-03 | LONGENECKER, JOHN P PHD | Director | ストックオプション | 購入 | 4,000 | $0.00 |
| 2015-06-03 | HASTINGS, PAUL J | Director | ストックオプション | 購入 | 4,000 | $0.00 |
| 2015-06-03 | WINGER, DENNIS L | Director | 普通株式 | 購入 | 2,000 | $0.00 |
| 2015-06-03 | RIKER, LAUREN BULLARO | Vice President, Finance | ストックオプション | 購入 | 7,500 | $0.00 |
| 2015-06-03 | RIKER, LAUREN BULLARO | Vice President, Finance | 普通株式 | 購入 | 3,750 | $0.00 |
| 2015-04-15 | STACK, DAVID M | Director, President, CEO and Chairman | 普通株式 | 購入 | 25,000 | $1.61 |
| 2015-04-15 | STACK, DAVID M | Director, President, CEO and Chairman | 普通株式 | 売却 | 25,000 | $90.50 |
| 2015-04-15 | STACK, DAVID M | Director, President, CEO and Chairman | ストックオプション | 売却 | 25,000 | $0.00 |
| 2015-04-10 | HASTINGS, PAUL J | Director | 普通株式 | 購入 | 2,500 | $13.98 |
| 2015-04-10 | HASTINGS, PAUL J | Director | 普通株式 | 売却 | 2,500 | $88.00 |
| 2015-04-10 | HASTINGS, PAUL J | Director | ストックオプション | 売却 | 2,500 | $0.00 |
| 2015-03-17 | MARKVICKA, TAUNIA | SVP, Chief Commercial Officer | ストックオプション | 売却 | 8,349 | $0.00 |
| 2015-03-17 | MARKVICKA, TAUNIA | SVP, Chief Commercial Officer | 普通株式 | 購入 | 8,349 | $5.49 |
| 2015-03-16 | RIKER, LAUREN BULLARO | Executive Director, Finance | ストックオプション | 売却 | 5,000 | $0.00 |
| 2015-03-16 | RIKER, LAUREN BULLARO | Executive Director, Finance | 普通株式 | 購入 | 5,000 | $10.34 |
| 2015-03-16 | RIKER, LAUREN BULLARO | Executive Director, Finance | 普通株式 | 売却 | 5,000 | $95.34 |
| 2015-03-13 | PACE, GARY W | Director | 普通株式 | 購入 | 1,000 | $93.83 |
| 2015-03-12 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 売却 | 3,000 | $95.28 |
| 2015-03-12 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 購入 | 3,000 | $29.90 |
| 2015-03-12 | LONGENECKER, JOHN P PHD | Director | ストックオプション | 売却 | 3,000 | $0.00 |
| 2015-02-06 | SCIBETTA, JAMES S | SVP, Chief Financial Officer | 普通株式 | 売却 | 3,103 | $111.98 |
| 2015-02-06 | SCIBETTA, JAMES S | SVP, Chief Financial Officer | 普通株式 | 購入 | 15,000 | $1.61 |
| 2015-02-06 | SCIBETTA, JAMES S | SVP, Chief Financial Officer | ストックオプション | 売却 | 15,000 | $0.00 |
| 2015-02-06 | SCIBETTA, JAMES S | SVP, Chief Financial Officer | 普通株式 | 売却 | 1,700 | $112.91 |
| 2015-02-06 | SCIBETTA, JAMES S | SVP, Chief Financial Officer | 普通株式 | 売却 | 4,293 | $110.17 |
| 2015-02-06 | SCIBETTA, JAMES S | SVP, Chief Financial Officer | 普通株式 | 売却 | 5,904 | $111.11 |
| 2015-01-15 | STACK, DAVID M | Director, President, CEO and Chairman | 普通株式 | 売却 | 2,500 | $97.71 |
| 2015-01-15 | STACK, DAVID M | Director, President, CEO and Chairman | ストックオプション | 売却 | 15,000 | $0.00 |
| 2015-01-15 | STACK, DAVID M | Director, President, CEO and Chairman | 普通株式 | 売却 | 1,600 | $98.74 |
| 2015-01-15 | STACK, DAVID M | Director, President, CEO and Chairman | 普通株式 | 売却 | 10,900 | $97.30 |
| 2015-01-15 | STACK, DAVID M | Director, President, CEO and Chairman | 普通株式 | 購入 | 15,000 | $1.61 |
| 2015-01-12 | HASTINGS, PAUL J | Director | 普通株式 | 購入 | 2,500 | $13.98 |
| 2015-01-12 | HASTINGS, PAUL J | Director | ストックオプション | 売却 | 2,500 | $0.00 |
| 2015-01-12 | HASTINGS, PAUL J | Director | 普通株式 | 売却 | 2,500 | $94.06 |
| 2014-12-29 | LONGENECKER, JOHN P PHD | Director | ストックオプション | 売却 | 1,000 | $0.00 |
| 2014-12-29 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 売却 | 1,000 | $93.32 |
| 2014-12-29 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 購入 | 1,000 | $29.90 |
| 2014-12-05 | WINGER, DENNIS L | Director | 普通株式 | 購入 | 2,645 | $94.54 |
| 2014-11-07 | SCIBETTA, JAMES S | SVP, Chief Financial Officer | 普通株式 | 売却 | 3,100 | $87.65 |
| 2014-11-07 | SCIBETTA, JAMES S | SVP, Chief Financial Officer | 普通株式 | 売却 | 8,600 | $86.99 |
| 2014-11-07 | SCIBETTA, JAMES S | SVP, Chief Financial Officer | 普通株式 | 売却 | 2,300 | $86.13 |
| 2014-11-07 | SCIBETTA, JAMES S | SVP, Chief Financial Officer | ストックオプション | 売却 | 15,000 | $0.00 |
| 2014-11-07 | SCIBETTA, JAMES S | SVP, Chief Financial Officer | 普通株式 | 売却 | 200 | $90.33 |
| 2014-11-07 | SCIBETTA, JAMES S | SVP, Chief Financial Officer | 普通株式 | 購入 | 15,000 | $1.61 |
| 2014-11-07 | MARKVICKA, TAUNIA | SVP, Chief Commercial Officer | 普通株式 | 購入 | 230 | $86.62 |
| 2014-11-07 | SCIBETTA, JAMES S | SVP, Chief Financial Officer | 普通株式 | 売却 | 800 | $89.56 |
| 2014-11-03 | KRONENFELD, MARK A. | Director | 普通株式 | 購入 | 850 | $90.48 |
| 2014-10-15 | STACK, DAVID M | Director, President, CEO and Chairman | ストックオプション | 売却 | 15,000 | $0.00 |
| 2014-10-15 | STACK, DAVID M | Director, President, CEO and Chairman | 普通株式 | 売却 | 1,198 | $101.20 |
| 2014-10-15 | STACK, DAVID M | Director, President, CEO and Chairman | 普通株式 | 売却 | 7,485 | $99.80 |
| 2014-10-15 | STACK, DAVID M | Director, President, CEO and Chairman | 普通株式 | 売却 | 5,417 | $99.05 |
| 2014-10-15 | STACK, DAVID M | Director, President, CEO and Chairman | 普通株式 | 売却 | 600 | $97.74 |
| 2014-10-15 | STACK, DAVID M | Director, President, CEO and Chairman | 普通株式 | 売却 | 300 | $96.60 |
| 2014-10-15 | STACK, DAVID M | Director, President, CEO and Chairman | 普通株式 | 購入 | 15,000 | $1.61 |
| 2014-10-10 | HASTINGS, PAUL J | Director | ストックオプション | 売却 | 2,500 | $0.00 |
| 2014-10-10 | HASTINGS, PAUL J | Director | 普通株式 | 購入 | 2,500 | $13.98 |
| 2014-10-10 | HASTINGS, PAUL J | Director | 普通株式 | 売却 | 2,500 | $94.87 |
| 2014-09-29 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 購入 | 1,000 | $29.90 |
| 2014-09-29 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 売却 | 1,000 | $96.40 |
| 2014-09-29 | LONGENECKER, JOHN P PHD | Director | ストックオプション | 売却 | 1,000 | $0.00 |
| 2014-09-09 | STACK, DAVID M | Director, President, CEO and Chairman | ストックオプション | 購入 | 350,000 | $0.00 |
| 2014-09-09 | STACK, DAVID M | Director, President, CEO and Chairman | ストックオプション | 購入 | 150,000 | $0.00 |
| 2014-09-09 | STACK, DAVID M | Director, President, CEO and Chairman | ストックオプション | 売却 | 350,000 | $0.00 |
| 2014-09-09 | STACK, DAVID M | Director, President, CEO and Chairman | ストックオプション | 売却 | 150,000 | $0.00 |
| 2014-08-29 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 10,481 | $108.15 |
| 2014-08-28 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 11,013 | $108.06 |
| 2014-08-27 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 1,606 | $108.05 |
| 2014-08-26 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 24,207 | $108.11 |
| 2014-08-25 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 30,000 | $108.07 |
| 2014-08-11 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 37,786 | $101.82 |
| 2014-08-11 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 30,114 | $101.20 |
| 2014-08-08 | SCIBETTA, JAMES S | SVP, Chief Financial Officer | 普通株式 | 購入 | 6,134 | $1.61 |
| 2014-08-08 | SCIBETTA, JAMES S | SVP, Chief Financial Officer | 普通株式 | 売却 | 5,000 | $99.22 |
| 2014-08-08 | SCIBETTA, JAMES S | SVP, Chief Financial Officer | 普通株式 | 売却 | 10,000 | $99.83 |
| 2014-08-08 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 82,100 | $101.00 |
| 2014-08-08 | SCIBETTA, JAMES S | SVP, Chief Financial Officer | 普通株式 | 購入 | 8,866 | $1.61 |
| 2014-08-08 | SCIBETTA, JAMES S | SVP, Chief Financial Officer | ストックオプション | 売却 | 6,134 | $0.00 |
| 2014-08-08 | SCIBETTA, JAMES S | SVP, Chief Financial Officer | ストックオプション | 売却 | 8,866 | $0.00 |
| 2014-08-07 | PATOU, GARY | Chief Medical Officer | ストックオプション | 売却 | 3,524 | $0.00 |
| 2014-08-07 | PATOU, GARY | Chief Medical Officer | ストックオプション | 売却 | 882 | $0.00 |
| 2014-08-07 | PATOU, GARY | Chief Medical Officer | ストックオプション | 売却 | 1,230 | $0.00 |
| 2014-08-07 | PATOU, GARY | Chief Medical Officer | 普通株式 | 売却 | 20,000 | $100.26 |
| 2014-08-07 | PATOU, GARY | Chief Medical Officer | 普通株式 | 購入 | 3,524 | $11.68 |
| 2014-08-07 | PATOU, GARY | Chief Medical Officer | 普通株式 | 購入 | 14,364 | $10.81 |
| 2014-08-07 | PATOU, GARY | Chief Medical Officer | 普通株式 | 購入 | 882 | $5.49 |
| 2014-08-07 | PATOU, GARY | Chief Medical Officer | 普通株式 | 購入 | 1,230 | $1.61 |
| 2014-08-07 | PATOU, GARY | Chief Medical Officer | ストックオプション | 売却 | 14,364 | $0.00 |
| 2014-07-15 | STACK, DAVID M | Director, President, CEO and Chairman | ストックオプション | 売却 | 15,000 | $0.00 |
| 2014-07-15 | STACK, DAVID M | Director, President, CEO and Chairman | 普通株式 | 売却 | 6,600 | $87.05 |
| 2014-07-15 | STACK, DAVID M | Director, President, CEO and Chairman | 普通株式 | 売却 | 7,400 | $86.28 |
| 2014-07-15 | STACK, DAVID M | Director, President, CEO and Chairman | 普通株式 | 売却 | 1,000 | $88.23 |
| 2014-07-15 | STACK, DAVID M | Director, President, CEO and Chairman | 普通株式 | 購入 | 15,000 | $1.61 |
| 2014-07-14 | PATOU, GARY | Chief Medical Officer | 普通株式 | 売却 | 2,107 | $87.58 |
| 2014-07-14 | PATOU, GARY | Chief Medical Officer | 普通株式 | 購入 | 20,237 | $5.49 |
| 2014-07-14 | PATOU, GARY | Chief Medical Officer | 普通株式 | 購入 | 2,460 | $1.61 |
| 2014-07-14 | PATOU, GARY | Chief Medical Officer | 普通株式 | 売却 | 27,593 | $86.91 |
| 2014-07-14 | PATOU, GARY | Chief Medical Officer | ストックオプション | 売却 | 7,303 | $0.00 |
| 2014-07-14 | PATOU, GARY | Chief Medical Officer | ストックオプション | 売却 | 20,237 | $0.00 |
| 2014-07-14 | PATOU, GARY | Chief Medical Officer | ストックオプション | 売却 | 2,460 | $0.00 |
| 2014-07-14 | PATOU, GARY | Chief Medical Officer | 普通株式 | 購入 | 7,303 | $10.81 |
| 2014-07-10 | HASTINGS, PAUL J | Director | 普通株式 | 売却 | 600 | $82.46 |
| 2014-07-10 | HASTINGS, PAUL J | Director | 普通株式 | 購入 | 2,500 | $13.98 |
| 2014-07-10 | HASTINGS, PAUL J | Director | ストックオプション | 売却 | 2,500 | $0.00 |
| 2014-07-10 | HASTINGS, PAUL J | Director | 普通株式 | 売却 | 698 | $85.96 |
| 2014-07-10 | HASTINGS, PAUL J | Director | 普通株式 | 売却 | 502 | $85.03 |
| 2014-07-10 | HASTINGS, PAUL J | Director | 普通株式 | 売却 | 700 | $84.08 |
| 2014-06-30 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 売却 | 1,000 | $91.60 |
| 2014-06-30 | LONGENECKER, JOHN P PHD | Director | ストックオプション | 売却 | 1,000 | $0.00 |
| 2014-06-30 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 購入 | 1,000 | $29.90 |
| 2014-06-09 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 9,289 | $86.43 |
| 2014-06-09 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 33,653 | $85.81 |
| 2014-06-09 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 25,058 | $84.55 |
| 2014-06-06 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 40,200 | $82.71 |
| 2014-06-05 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 23,200 | $82.53 |
| 2014-06-04 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 4,500 | $82.40 |
| 2014-06-03 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 57,400 | $80.72 |
| 2014-06-03 | RIKER, LAUREN BULLARO | Executive Director, Finance | ストックオプション | 購入 | 15,000 | $0.00 |
| 2014-06-03 | MARKVICKA, TAUNIA | Vice President, Commercial | ストックオプション | 購入 | 70,000 | $0.00 |
| 2014-06-03 | SCIBETTA, JAMES S | SVP, Chief Financial Officer | ストックオプション | 購入 | 70,000 | $0.00 |
| 2014-06-03 | GREENSTREET, YVONNE | Director | ストックオプション | 購入 | 8,000 | $0.00 |
| 2014-06-03 | LONGENECKER, JOHN P PHD | Director | ストックオプション | 購入 | 8,000 | $0.00 |
| 2014-06-03 | HASTINGS, PAUL J | Director | ストックオプション | 購入 | 8,000 | $0.00 |
| 2014-06-03 | BREGE, LAURA | Director | ストックオプション | 購入 | 8,000 | $0.00 |
| 2014-06-03 | PACE, GARY W | Director | ストックオプション | 購入 | 8,000 | $0.00 |
| 2014-06-03 | WINGER, DENNIS L | Director | ストックオプション | 購入 | 8,000 | $0.00 |
| 2014-06-03 | KRONENFELD, MARK A. | Director | ストックオプション | 購入 | 8,000 | $0.00 |
| 2014-06-03 | STACK, DAVID M | Director, President, CEO and Chairman | ストックオプション | 購入 | 150,000 | $0.00 |
| 2014-06-03 | PATOU, GARY | Chief Medical Officer | ストックオプション | 購入 | 25,000 | $0.00 |
| 2014-06-02 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 10,600 | $80.52 |
| 2014-05-27 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 64,400 | $77.93 |
| 2014-05-21 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 3,600 | $77.80 |
| 2014-05-12 | PATOU, GARY | Chief Medical Officer | 普通株式 | 購入 | 10,000 | $5.49 |
| 2014-05-12 | PATOU, GARY | Chief Medical Officer | 普通株式 | 売却 | 10,000 | $75.00 |
| 2014-05-12 | PATOU, GARY | Chief Medical Officer | ストックオプション | 売却 | 10,000 | $0.00 |
| 2014-05-09 | BREGE, LAURA | Director | 普通株式 | 購入 | 3,000 | $13.98 |
| 2014-05-09 | BREGE, LAURA | Director | 普通株式 | 売却 | 7,500 | $73.57 |
| 2014-05-09 | BREGE, LAURA | Director | 普通株式 | 売却 | 2,500 | $74.67 |
| 2014-05-09 | BREGE, LAURA | Director | ストックオプション | 売却 | 7,000 | $0.00 |
| 2014-05-09 | BREGE, LAURA | Director | ストックオプション | 売却 | 3,000 | $0.00 |
| 2014-05-09 | STACK, DAVID M | Director, President, CEO and Chairman | 普通株式 | 売却 | 7,400 | $73.40 |
| 2014-05-09 | STACK, DAVID M | Director, President, CEO and Chairman | ストックオプション | 売却 | 25,000 | $0.00 |
| 2014-05-09 | BREGE, LAURA | Director | 普通株式 | 購入 | 7,000 | $10.81 |
| 2014-05-09 | PATOU, GARY | Chief Medical Officer | 普通株式 | 購入 | 6,836 | $5.49 |
| 2014-05-09 | PATOU, GARY | Chief Medical Officer | 普通株式 | 売却 | 20,000 | $74.08 |
| 2014-05-09 | PATOU, GARY | Chief Medical Officer | ストックオプション | 売却 | 6,836 | $0.00 |
| 2014-05-09 | PATOU, GARY | Chief Medical Officer | ストックオプション | 売却 | 13,164 | $0.00 |
| 2014-05-09 | PATOU, GARY | Chief Medical Officer | 普通株式 | 購入 | 13,164 | $1.61 |
| 2014-05-09 | STACK, DAVID M | Director, President, CEO and Chairman | 普通株式 | 売却 | 17,300 | $74.15 |
| 2014-05-09 | STACK, DAVID M | Director, President, CEO and Chairman | 普通株式 | 購入 | 25,000 | $1.61 |
| 2014-05-09 | STACK, DAVID M | Director, President, CEO and Chairman | 普通株式 | 売却 | 300 | $74.80 |
| 2014-05-08 | SCIBETTA, JAMES S | SVP, Chief Financial Officer | 普通株式 | 売却 | 3,300 | $74.27 |
| 2014-05-08 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 23,220 | $75.76 |
| 2014-05-08 | SCIBETTA, JAMES S | SVP, Chief Financial Officer | 普通株式 | 売却 | 11,400 | $75.25 |
| 2014-05-08 | SCIBETTA, JAMES S | SVP, Chief Financial Officer | 普通株式 | 売却 | 300 | $75.80 |
| 2014-05-08 | SCIBETTA, JAMES S | SVP, Chief Financial Officer | ストックオプション | 売却 | 15,000 | $0.00 |
| 2014-05-08 | SCIBETTA, JAMES S | SVP, Chief Financial Officer | 普通株式 | 購入 | 15,000 | $1.61 |
| 2014-05-07 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 600 | $75.64 |
| 2014-05-06 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 44,180 | $75.78 |
| 2014-03-28 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 購入 | 1,000 | $29.90 |
| 2014-03-28 | LONGENECKER, JOHN P PHD | Director | ストックオプション | 売却 | 1,000 | $0.00 |
| 2014-03-28 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 売却 | 1,000 | $64.63 |
| 2014-03-11 | PATOU, GARY | Chief Medical Officer | 普通株式 | 購入 | 504 | $0.00 |
| 2014-03-11 | STACK, DAVID M | Director, President, CEO and Chairman | 普通株式 | 購入 | 221 | $0.00 |
| 2014-03-06 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 2,200 | $80.11 |
| 2014-03-05 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 22,687 | $80.16 |
| 2014-03-04 | GREENSTREET, YVONNE | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2013-12-30 | SCIBETTA, JAMES S | Chief Financial Officer | 普通株式 | 売却 | 10,000 | $55.55 |
| 2013-12-30 | STACK, DAVID M | Director, President and CEO | 普通株式 | 購入 | 15,000 | $1.61 |
| 2013-12-30 | STACK, DAVID M | Director, President and CEO | 普通株式 | 売却 | 15,000 | $55.84 |
| 2013-12-30 | STACK, DAVID M | Director, President and CEO | ストックオプション | 売却 | 15,000 | $0.00 |
| 2013-12-30 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 購入 | 581 | $1.61 |
| 2013-12-30 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 購入 | 1,345 | $1.61 |
| 2013-12-30 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 購入 | 574 | $1.61 |
| 2013-12-30 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 売却 | 2,500 | $55.55 |
| 2013-12-30 | LONGENECKER, JOHN P PHD | Director | ストックオプション | 売却 | 581 | $0.00 |
| 2013-12-30 | LONGENECKER, JOHN P PHD | Director | ストックオプション | 売却 | 1,345 | $0.00 |
| 2013-12-30 | LONGENECKER, JOHN P PHD | Director | ストックオプション | 売却 | 574 | $0.00 |
| 2013-12-30 | SCIBETTA, JAMES S | Chief Financial Officer | 普通株式 | 購入 | 10,000 | $1.61 |
| 2013-12-30 | SCIBETTA, JAMES S | Chief Financial Officer | ストックオプション | 売却 | 10,000 | $0.00 |
| 2013-11-18 | PATOU, GARY | Chief Medical Officer | 普通株式 | 購入 | 83 | $0.00 |
| 2013-11-18 | STACK, DAVID M | Director, President and CEO | 普通株式 | 購入 | 414 | $0.00 |
| 2013-11-06 | MARKVICKA, TAUNIA | Vice President, Commercial | 普通株式 | 売却 | 1,802 | $53.61 |
| 2013-11-06 | MARKVICKA, TAUNIA | Vice President, Commercial | 普通株式 | 売却 | 5,681 | $52.49 |
| 2013-11-06 | MARKVICKA, TAUNIA | Vice President, Commercial | 普通株式 | 売却 | 14,123 | $51.36 |
| 2013-11-06 | MARKVICKA, TAUNIA | Vice President, Commercial | 普通株式 | 売却 | 28,394 | $50.60 |
| 2013-11-06 | MARKVICKA, TAUNIA | Vice President, Commercial | 普通株式 | 購入 | 50,000 | $10.81 |
| 2013-11-06 | MARKVICKA, TAUNIA | Vice President, Commercial | ストックオプション | 売却 | 50,000 | $0.00 |
| 2013-10-01 | PATOU, GARY | Chief Medical Officer | 普通株式 | 購入 | 20,000 | $1.61 |
| 2013-10-01 | PATOU, GARY | Chief Medical Officer | 普通株式 | 売却 | 20,000 | $48.92 |
| 2013-10-01 | PATOU, GARY | Chief Medical Officer | ストックオプション | 売却 | 20,000 | $0.00 |
| 2013-09-30 | STACK, DAVID M | Director, President and CEO | 普通株式 | 購入 | 15,000 | $1.61 |
| 2013-09-30 | STACK, DAVID M | Director, President and CEO | 普通株式 | 売却 | 1,094 | $47.55 |
| 2013-09-30 | STACK, DAVID M | Director, President and CEO | ストックオプション | 売却 | 15,000 | $0.00 |
| 2013-09-30 | LONGENECKER, JOHN P PHD | Director | ストックオプション | 売却 | 2,500 | $0.00 |
| 2013-09-30 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 売却 | 2,500 | $46.74 |
| 2013-09-30 | SCIBETTA, JAMES S | Chief Financial Officer | 普通株式 | 購入 | 10,000 | $1.61 |
| 2013-09-30 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 購入 | 2,500 | $1.61 |
| 2013-09-30 | STACK, DAVID M | Director, President and CEO | 普通株式 | 売却 | 13,906 | $47.01 |
| 2013-09-30 | SCIBETTA, JAMES S | Chief Financial Officer | 普通株式 | 売却 | 10,000 | $46.74 |
| 2013-09-30 | SCIBETTA, JAMES S | Chief Financial Officer | ストックオプション | 売却 | 10,000 | $0.00 |
| 2013-09-25 | MARKVICKA, TAUNIA | Vice President, Commercial | 普通株式 | 購入 | 10,000 | $5.49 |
| 2013-09-25 | MARKVICKA, TAUNIA | Vice President, Commercial | 普通株式 | 売却 | 10,000 | $47.00 |
| 2013-09-25 | MARKVICKA, TAUNIA | Vice President, Commercial | ストックオプション | 売却 | 10,000 | $0.00 |
| 2013-09-11 | WINGER, DENNIS L | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2013-09-11 | KRONENFELD, MARK A. | Director | 普通株式 | 購入 | 1,000 | $37.01 |
| 2013-09-11 | WICKI, ANDREAS | Director | 普通株式 | 購入 | 37,192 | $2.69 |
| 2013-09-11 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 2,686 | $37.25 |
| 2013-09-11 | WICKI, ANDREAS | Director | 普通株式 | 購入 | 41,841 | $13.44 |
| 2013-09-11 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 15,097 | $37.25 |
| 2013-09-11 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 37,192 | $0.00 |
| 2013-09-11 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 41,841 | $0.00 |
| 2013-08-14 | MARKVICKA, TAUNIA | Vice President, Commercial | 普通株式 | 購入 | 14,700 | $1.61 |
| 2013-08-14 | MARKVICKA, TAUNIA | Vice President, Commercial | 普通株式 | 売却 | 14,700 | $37.00 |
| 2013-08-14 | MARKVICKA, TAUNIA | Vice President, Commercial | ストックオプション | 売却 | 14,700 | $0.00 |
| 2013-07-22 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 19,938 | $35.28 |
| 2013-07-19 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 56,020 | $34.98 |
| 2013-07-18 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 4,042 | $34.80 |
| 2013-07-17 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 21,518 | $33.20 |
| 2013-07-16 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 350 | $33.20 |
| 2013-07-15 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 48,132 | $33.28 |
| 2013-07-12 | MARKVICKA, TAUNIA | Vice President, Commercial | 普通株式 | 売却 | 29,754 | $32.00 |
| 2013-07-12 | MARKVICKA, TAUNIA | Vice President, Commercial | 普通株式 | 購入 | 29,754 | $1.61 |
| 2013-07-12 | MARKVICKA, TAUNIA | Vice President, Commercial | ストックオプション | 売却 | 29,754 | $0.00 |
| 2013-07-11 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 80,000 | $31.48 |
| 2013-07-05 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 44,021 | $30.80 |
| 2013-07-03 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 50,000 | $30.67 |
| 2013-07-02 | PATOU, GARY | Chief Medical Officer | ストックオプション | 売却 | 10,000 | $0.00 |
| 2013-07-02 | PATOU, GARY | Chief Medical Officer | 普通株式 | 購入 | 10,000 | $1.61 |
| 2013-07-02 | PATOU, GARY | Chief Medical Officer | 普通株式 | 売却 | 10,000 | $30.00 |
| 2013-07-02 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 60,597 | $29.85 |
| 2013-07-01 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 3,851 | $29.85 |
| 2013-07-01 | PATOU, GARY | Chief Medical Officer | ストックオプション | 売却 | 10,958 | $0.00 |
| 2013-07-01 | PATOU, GARY | Chief Medical Officer | ストックオプション | 売却 | 19,042 | $0.00 |
| 2013-07-01 | PATOU, GARY | Chief Medical Officer | 普通株式 | 売却 | 30,000 | $29.25 |
| 2013-07-01 | PATOU, GARY | Chief Medical Officer | 普通株式 | 購入 | 30,000 | $1.61 |
| 2013-06-28 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 購入 | 1,196 | $1.61 |
| 2013-06-28 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 購入 | 804 | $1.61 |
| 2013-06-28 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 売却 | 2,000 | $28.09 |
| 2013-06-28 | LONGENECKER, JOHN P PHD | Director | ストックオプション | 売却 | 1,196 | $0.00 |
| 2013-06-28 | LONGENECKER, JOHN P PHD | Director | ストックオプション | 売却 | 804 | $0.00 |
| 2013-06-28 | SCIBETTA, JAMES S | Chief Financial Officer | 普通株式 | 購入 | 10,000 | $1.61 |
| 2013-06-28 | SCIBETTA, JAMES S | Chief Financial Officer | 普通株式 | 売却 | 10,000 | $28.05 |
| 2013-06-28 | SCIBETTA, JAMES S | Chief Financial Officer | ストックオプション | 売却 | 10,000 | $0.00 |
| 2013-06-28 | STACK, DAVID M | Director, President and CEO | 普通株式 | 購入 | 15,000 | $1.61 |
| 2013-06-28 | STACK, DAVID M | Director, President and CEO | 普通株式 | 売却 | 15,000 | $28.73 |
| 2013-06-28 | STACK, DAVID M | Director, President and CEO | ストックオプション | 売却 | 15,000 | $0.00 |
| 2013-06-24 | MIDDLETON, FRED A | Director | 普通株式 | 売却 | 5,900 | $28.70 |
| 2013-06-21 | MIDDLETON, FRED A | Director | 普通株式 | 売却 | 2,828 | $28.49 |
| 2013-06-21 | MIDDLETON, FRED A | Director | 普通株式 | 売却 | 36,374 | $29.22 |
| 2013-06-21 | MIDDLETON, FRED A | Director | 普通株式 | 売却 | 2,222 | $28.49 |
| 2013-06-21 | MIDDLETON, FRED A | Director | 普通株式 | 売却 | 28,576 | $29.22 |
| 2013-06-20 | MIDDLETON, FRED A | Director | 普通株式 | 売却 | 66,100 | $28.93 |
| 2013-06-19 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 35,407 | $29.90 |
| 2013-06-19 | MIDDLETON, FRED A | Director | 普通株式 | 売却 | 48,400 | $29.76 |
| 2013-06-18 | MIDDLETON, FRED A | Director | 普通株式 | 売却 | 29,600 | $29.48 |
| 2013-06-17 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 50,145 | $29.86 |
| 2013-06-13 | PRATT, JOHN | General Manager, San Diego | 普通株式 | 購入 | 1,875 | $8.73 |
| 2013-06-13 | EVNIN, LUKE | Director | 普通株式 | 売却 | 20,311 | $30.07 |
| 2013-06-13 | PRATT, JOHN | General Manager, San Diego | 普通株式 | 売却 | 18,232 | $30.00 |
| 2013-06-13 | PRATT, JOHN | General Manager, San Diego | ストックオプション | 売却 | 18,232 | $0.00 |
| 2013-06-13 | PRATT, JOHN | General Manager, San Diego | 普通株式 | 購入 | 18,232 | $10.81 |
| 2013-06-13 | PRATT, JOHN | General Manager, San Diego | ストックオプション | 売却 | 1,875 | $0.00 |
| 2013-06-13 | PRATT, JOHN | General Manager, San Diego | 普通株式 | 売却 | 1,875 | $30.00 |
| 2013-06-12 | MIDDLETON, FRED A | Director | ストックオプション | 購入 | 7,000 | $0.00 |
| 2013-06-12 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 4,409 | $30.00 |
| 2013-06-12 | PRATT, JOHN | General Manager, San Diego | ストックオプション | 売却 | 925 | $0.00 |
| 2013-06-12 | EVNIN, LUKE | Director | ストックオプション | 購入 | 7,000 | $0.00 |
| 2013-06-12 | BREGE, LAURA | Director | ストックオプション | 購入 | 7,000 | $0.00 |
| 2013-06-12 | HASTINGS, PAUL J | Director | ストックオプション | 購入 | 7,000 | $0.00 |
| 2013-06-12 | EVNIN, LUKE | Director | 普通株式 | 売却 | 2,435 | $30.00 |
| 2013-06-12 | PRATT, JOHN | General Manager, San Diego | 普通株式 | 購入 | 925 | $10.81 |
| 2013-06-12 | PRATT, JOHN | General Manager, San Diego | 普通株式 | 売却 | 925 | $30.00 |
| 2013-06-12 | PACE, GARY W | Director | ストックオプション | 購入 | 7,000 | $0.00 |
| 2013-06-12 | LONGENECKER, JOHN P PHD | Director | ストックオプション | 購入 | 7,000 | $0.00 |
| 2013-06-12 | KRONENFELD, MARK A. | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2013-06-11 | PRATT, JOHN | General Manager, San Diego | 普通株式 | 売却 | 12,945 | $30.00 |
| 2013-06-11 | PRATT, JOHN | General Manager, San Diego | 普通株式 | 購入 | 12,945 | $10.81 |
| 2013-06-11 | PRATT, JOHN | General Manager, San Diego | ストックオプション | 売却 | 12,945 | $0.00 |
| 2013-06-11 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 9,000 | $30.00 |
| 2013-06-10 | PRATT, JOHN | General Manager, San Diego | 普通株式 | 売却 | 5,398 | $30.00 |
| 2013-06-10 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 2,500 | $30.00 |
| 2013-06-10 | PRATT, JOHN | General Manager, San Diego | ストックオプション | 売却 | 5,398 | $0.00 |
| 2013-06-10 | PRATT, JOHN | General Manager, San Diego | 普通株式 | 購入 | 5,398 | $10.81 |
| 2013-06-05 | MIDDLETON, FRED A | Director | 普通株式 | 売却 | 241,185 | $0.00 |
| 2013-06-05 | MIDDLETON, FRED A | Director | 普通株式 | 購入 | 7,433 | $0.00 |
| 2013-06-05 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 2,500 | $30.00 |
| 2013-06-05 | MIDDLETON, FRED A | Director | 普通株式 | 売却 | 316,660 | $0.00 |
| 2013-06-04 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 13,000 | $30.31 |
| 2013-06-03 | EVNIN, LUKE | Director | 普通株式 | 売却 | 82,072 | $30.00 |
| 2013-06-03 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 1,900 | $30.00 |
| 2013-05-31 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 3,033 | $30.00 |
| 2013-05-31 | EVNIN, LUKE | Director | 普通株式 | 売却 | 9,935 | $30.00 |
| 2013-05-30 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 2,500 | $30.00 |
| 2013-05-30 | EVNIN, LUKE | Director | 普通株式 | 売却 | 44,582 | $30.00 |
| 2013-05-29 | EVNIN, LUKE | Director | 普通株式 | 売却 | 20,411 | $30.00 |
| 2013-05-28 | EVNIN, LUKE | Director | 普通株式 | 売却 | 74,980 | $31.38 |
| 2013-05-28 | EVNIN, LUKE | Director | 普通株式 | 売却 | 114,837 | $30.62 |
| 2013-05-28 | EVNIN, LUKE | Director | 普通株式 | 売却 | 5,300 | $32.14 |
| 2013-05-22 | EVNIN, LUKE | Director | 普通株式 | 売却 | 7,340 | $30.00 |
| 2013-05-22 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 18,471 | $30.00 |
| 2013-05-20 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 14,374 | $30.00 |
| 2013-05-20 | EVNIN, LUKE | Director | 普通株式 | 売却 | 13,550 | $30.00 |
| 2013-05-15 | HASTINGS, PAUL J | Director | 普通株式 | 購入 | 853 | $29.30 |
| 2013-04-24 | EVNIN, LUKE | Director | 普通株式 | 売却 | 6,303 | $30.04 |
| 2013-04-24 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 401 | $30.04 |
| 2013-04-23 | EVNIN, LUKE | Director | 普通株式 | 売却 | 108,115 | $30.00 |
| 2013-04-23 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 15,646 | $30.00 |
| 2013-04-15 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 6,400 | $30.00 |
| 2013-04-15 | EVNIN, LUKE | Director | 普通株式 | 売却 | 2,575 | $30.00 |
| 2013-04-12 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 34,294 | $30.00 |
| 2013-04-12 | EVNIN, LUKE | Director | 普通株式 | 購入 | 37,192 | $2.69 |
| 2013-04-12 | EVNIN, LUKE | Director | 普通株式 | 売却 | 3,416 | $29.30 |
| 2013-04-12 | EVNIN, LUKE | Director | 普通株式 | 売却 | 37,192 | $0.00 |
| 2013-04-12 | PATOU, GARY | Chief Medical Officer | 普通株式 | 売却 | 10,000 | $30.00 |
| 2013-04-12 | PATOU, GARY | Chief Medical Officer | ストックオプション | 購入 | 10,000 | $0.00 |
| 2013-04-12 | EVNIN, LUKE | Director | 普通株式 | 売却 | 10,000 | $30.00 |
| 2013-04-12 | PATOU, GARY | Chief Medical Officer | 普通株式 | 購入 | 10,000 | $1.61 |
| 2013-04-11 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 600 | $30.00 |
| 2013-04-01 | PATOU, GARY | Chief Medical Officer | 普通株式 | 売却 | 11,300 | $28.82 |
| 2013-04-01 | PATOU, GARY | Chief Medical Officer | 普通株式 | 購入 | 30,000 | $1.61 |
| 2013-04-01 | PATOU, GARY | Chief Medical Officer | 普通株式 | 売却 | 18,700 | $27.75 |
| 2013-04-01 | PATOU, GARY | Chief Medical Officer | ストックオプション | 購入 | 30,000 | $0.00 |
| 2013-03-28 | SCIBETTA, JAMES S | Chief Financial Officer | ストックオプション | 売却 | 10,000 | $0.00 |
| 2013-03-28 | STACK, DAVID M | Director, President and CEO | ストックオプション | 売却 | 15,000 | $0.00 |
| 2013-03-28 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 購入 | 2,000 | $1.61 |
| 2013-03-28 | SCIBETTA, JAMES S | Chief Financial Officer | 普通株式 | 売却 | 10,000 | $28.49 |
| 2013-03-28 | LONGENECKER, JOHN P PHD | Director | ストックオプション | 売却 | 2,000 | $0.00 |
| 2013-03-28 | STACK, DAVID M | Director, President and CEO | 普通株式 | 売却 | 15,000 | $28.66 |
| 2013-03-28 | STACK, DAVID M | Director, President and CEO | 普通株式 | 購入 | 15,000 | $1.61 |
| 2013-03-28 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 売却 | 2,000 | $28.49 |
| 2013-03-28 | SCIBETTA, JAMES S | Chief Financial Officer | 普通株式 | 購入 | 10,000 | $1.61 |
| 2013-03-25 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 165,541 | $28.28 |
| 2013-03-25 | HBM, HEALTHCARE INVESTMENTS (CAYMAN) LTD. | 10% Owner | 普通株式 | 売却 | 165,541 | $28.28 |
| 2013-03-22 | HBM, HEALTHCARE INVESTMENTS (CAYMAN) LTD. | 10% Owner | 普通株式 | 売却 | 113,928 | $27.52 |
| 2013-03-22 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 113,928 | $27.52 |
| 2013-03-21 | HBM, HEALTHCARE INVESTMENTS (CAYMAN) LTD. | 10% Owner | 普通株式 | 売却 | 11,431 | $27.50 |
| 2013-03-21 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 11,431 | $27.50 |
| 2013-03-19 | SANDERLING, VENTURE PARTNERS VI LP | Director | 普通株式 | 売却 | 38,250 | $27.66 |
| 2013-03-19 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 9,100 | $27.86 |
| 2013-03-19 | HBM, BIOVENTURES CAYMAN LTD | 10% Owner | 普通株式 | 売却 | 9,100 | $27.86 |
| 2013-03-19 | SANDERLING, VENTURE PARTNERS VI LP | Director | 普通株式 | 売却 | 46,339 | $26.95 |
| 2013-03-18 | STACK, DAVID M | Director, President and CEO | 普通株式 | 購入 | 573 | $0.00 |
| 2013-03-18 | SANDERLING, VENTURE PARTNERS VI LP | Director | 普通株式 | 売却 | 23,969 | $29.20 |
| 2013-03-18 | EVNIN, LUKE | Director | 普通株式 | 売却 | 500,000 | $28.44 |
| 2013-03-18 | SANDERLING, VENTURE PARTNERS VI LP | Director | 普通株式 | 売却 | 28,956 | $29.20 |
| 2013-03-18 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 400,000 | $28.19 |
| 2013-03-18 | HBM, BIOVENTURES CAYMAN LTD | 10% Owner | 普通株式 | 売却 | 400,000 | $28.19 |
| 2013-03-18 | SANDERLING, VENTURE PARTNERS VI LP | Director | 普通株式 | 売却 | 28,558 | $29.20 |
| 2013-03-18 | SANDERLING, VENTURE PARTNERS VI LP | Director | 普通株式 | 売却 | 29,825 | $28.19 |
| 2013-03-18 | SANDERLING, VENTURE PARTNERS VI LP | Director | 普通株式 | 売却 | 29,415 | $28.19 |
| 2013-03-18 | SANDERLING, VENTURE PARTNERS VI LP | Director | 普通株式 | 売却 | 24,688 | $28.19 |
| 2013-03-15 | SANDERLING, VENTURE PARTNERS VI LP | Director | 普通株式 | 購入 | 25,133 | $0.00 |
| 2013-03-15 | SANDERLING, VENTURE PARTNERS VI LP | Director | 普通株式 | 売却 | 200,000 | $0.00 |
| 2013-03-15 | SANDERLING, VENTURE PARTNERS VI LP | 10% Owner | 普通株式 | 売却 | 1,000,000 | $0.00 |
| 2013-03-15 | SANDERLING, VENTURE PARTNERS VI LP | 10% Owner | 普通株式 | 購入 | 200,000 | $0.00 |
| 2013-03-14 | RIKER, LAUREN BULLARO | Executive Director, Accounting | 普通株式 | 売却 | 10,000 | $30.00 |
| 2013-03-14 | RIKER, LAUREN BULLARO | Executive Director, Accounting | 普通株式 | 購入 | 10,000 | $10.34 |
| 2013-03-14 | RIKER, LAUREN BULLARO | Executive Director, Accounting | ストックオプション | 売却 | 10,000 | $0.00 |
| 2013-03-12 | PRATT, JOHN | General Manager, San Diego | 普通株式 | 売却 | 9,375 | $28.46 |
| 2013-03-12 | PRATT, JOHN | General Manager, San Diego | ストックオプション | 売却 | 9,375 | $0.00 |
| 2013-03-12 | PRATT, JOHN | General Manager, San Diego | 普通株式 | 購入 | 9,375 | $8.73 |
| 2013-03-11 | MPM, BIOVENTURES IV QP LP | Former 10% Owner | 普通株式 | 売却 | 500,000 | $27.86 |
| 2013-03-11 | EVNIN, LUKE | Director | 普通株式 | 売却 | 500,000 | $27.86 |
| 2013-03-11 | KAILIAN, VAUGHN M | Former 10% Owner | 普通株式 | 売却 | 500,000 | $27.86 |
| 2013-03-11 | SANDERLING, VENTURE PARTNERS VI LP | 10% Owner | 普通株式 | 売却 | 348,951 | $27.86 |
| 2013-03-11 | WICKI, ANDREAS | Director | 普通株式 | 売却 | 500,000 | $27.86 |
| 2013-03-11 | HBM, BIOVENTURES CAYMAN LTD | 10% Owner | 普通株式 | 売却 | 500,000 | $27.86 |
| 2013-03-07 | SANDERLING, VENTURE PARTNERS VI LP | 10% Owner | 普通株式 | 売却 | 10,485 | $25.92 |
| 2013-03-07 | SANDERLING, VENTURE PARTNERS VI LP | 10% Owner | 普通株式 | 売却 | 66 | $25.92 |
| 2013-03-07 | SANDERLING, VENTURE PARTNERS VI LP | 10% Owner | 普通株式 | 売却 | 78 | $25.92 |
| 2013-03-07 | SANDERLING, VENTURE PARTNERS VI LP | 10% Owner | 普通株式 | 売却 | 1,852 | $25.92 |
| 2013-03-07 | SANDERLING, VENTURE PARTNERS VI LP | 10% Owner | 普通株式 | 購入 | 20,220 | $13.44 |
| 2013-03-07 | SANDERLING, VENTURE PARTNERS VI LP | 10% Owner | 普通株式 | 売却 | 843 | $0.00 |
| 2013-03-07 | SANDERLING, VENTURE PARTNERS VI LP | 10% Owner | 普通株式 | 売却 | 708 | $0.00 |
| 2013-03-07 | SANDERLING, VENTURE PARTNERS VI LP | 10% Owner | 普通株式 | 売却 | 20,220 | $0.00 |
| 2013-03-07 | SANDERLING, VENTURE PARTNERS VI LP | 10% Owner | 普通株式 | 売却 | 17,839 | $0.00 |
| 2013-03-07 | SANDERLING, VENTURE PARTNERS VI LP | 10% Owner | 普通株式 | 売却 | 750 | $0.00 |
| 2013-03-07 | SANDERLING, VENTURE PARTNERS VI LP | 10% Owner | 普通株式 | 売却 | 629 | $0.00 |
| 2013-03-07 | SANDERLING, VENTURE PARTNERS VI LP | 10% Owner | 普通株式 | 売却 | 17,973 | $0.00 |
| 2013-03-07 | SANDERLING, VENTURE PARTNERS VI LP | 10% Owner | 普通株式 | 売却 | 10,407 | $25.92 |
| 2013-03-07 | SANDERLING, VENTURE PARTNERS VI LP | 10% Owner | 普通株式 | 売却 | 438 | $25.92 |
| 2013-03-07 | SANDERLING, VENTURE PARTNERS VI LP | 10% Owner | 普通株式 | 売却 | 368 | $25.92 |
| 2013-03-07 | SANDERLING, VENTURE PARTNERS VI LP | 10% Owner | 普通株式 | 売却 | 1,866 | $25.92 |
| 2013-03-07 | SANDERLING, VENTURE PARTNERS VI LP | 10% Owner | 普通株式 | 購入 | 17,839 | $2.69 |
| 2013-03-07 | SANDERLING, VENTURE PARTNERS VI LP | 10% Owner | 普通株式 | 購入 | 750 | $2.69 |
| 2013-03-07 | SANDERLING, VENTURE PARTNERS VI LP | 10% Owner | 普通株式 | 購入 | 629 | $2.69 |
| 2013-03-07 | SANDERLING, VENTURE PARTNERS VI LP | 10% Owner | 普通株式 | 購入 | 17,973 | $2.69 |
| 2013-03-07 | SANDERLING, VENTURE PARTNERS VI LP | 10% Owner | 普通株式 | 売却 | 20,069 | $0.00 |
| 2013-03-07 | SANDERLING, VENTURE PARTNERS VI LP | 10% Owner | 普通株式 | 購入 | 708 | $13.44 |
| 2013-03-07 | SANDERLING, VENTURE PARTNERS VI LP | 10% Owner | 普通株式 | 購入 | 843 | $13.44 |
| 2013-03-07 | SANDERLING, VENTURE PARTNERS VI LP | 10% Owner | 普通株式 | 購入 | 20,069 | $13.44 |
| 2013-01-24 | SANDERLING, VENTURE PARTNERS VI LP | 10% Owner | 普通株式 | 売却 | 500,000 | $18.93 |
| 2012-12-06 | SANDERLING, VENTURE PARTNERS VI LP | 10% Owner | 普通株式 | 売却 | 98,596 | $0.00 |
| 2012-08-17 | PACE, GARY W | Director | ストックオプション | 購入 | 70,000 | $0.00 |
| 2012-06-07 | PATOU, GARY | Chief Medical Officer | ストックオプション | 購入 | 60,000 | $0.00 |
| 2012-06-05 | LONGENECKER, JOHN P PHD | Director | 普通株式 | 購入 | 7,000 | $0.00 |
| 2012-06-05 | PACE, GARY W | Director | 普通株式 | 購入 | 7,000 | $0.00 |
| 2012-06-05 | SCIBETTA, JAMES S | Chief Financial Officer | 普通株式 | 購入 | 150,000 | $0.00 |
| 2012-06-05 | PATOU, GARY | Chief Medical Officer | ストックオプション | 購入 | 40,000 | $0.00 |
| 2012-06-05 | EVNIN, LUKE | Director, 10% Owner | ストックオプション | 購入 | 7,000 | $0.00 |
| 2012-06-05 | PATOU, GARY | Director | ストックオプション | 購入 | 40,000 | $0.00 |
| 2012-06-05 | MARKVICKA, TAUNIA | Vice President, Commercial | 普通株式 | 購入 | 150,000 | $0.00 |
| 2012-06-05 | BREGE, LAURA | Director | 普通株式 | 購入 | 7,000 | $0.00 |
| 2012-06-05 | PRATT, JOHN | General Manager, San Diego | 普通株式 | 購入 | 150,000 | $0.00 |
| 2012-06-05 | STACK, DAVID M | Director, President and CEO | 普通株式 | 購入 | 350,000 | $0.00 |
| 2012-06-05 | HASTINGS, PAUL J | Director | 普通株式 | 購入 | 7,000 | $0.00 |
| 2012-06-05 | MIDDLETON, FRED A | Director, 10% Owner | 普通株式 | 購入 | 7,000 | $0.00 |
| 2012-06-05 | RIKER, LAUREN BULLARO | Executive Director, Accounting | 普通株式 | 購入 | 30,000 | $0.00 |
| 2012-04-17 | PACE, GARY W | Director | 普通株式 | 購入 | 10,000 | $9.75 |
| 2012-04-03 | PACE, GARY W | Director | 普通株式 | 購入 | 20,000 | $0.00 |
| 2012-04-03 | PACE, GARY W | Director | 普通株式 | 購入 | 10,000 | $0.00 |
| 2012-03-25 | MIDDLETON, FRED A | Director | 普通株式 | 売却 | 5,000 | $0.00 |
| 2012-03-12 | ORBIMED, ADVISORS LLC | 10% Owner | 普通株式 | 売却 | 700 | $11.03 |
| 2012-03-12 | ORBIMED, ADVISORS LLC | 10% Owner | 普通株式 | 売却 | 62,400 | $11.03 |
| 2012-03-09 | ORBIMED, ADVISORS LLC | 10% Owner | 普通株式 | 売却 | 300 | $11.25 |
| 2012-03-09 | ORBIMED, ADVISORS LLC | 10% Owner | 普通株式 | 売却 | 36,700 | $11.25 |
| 2012-02-29 | ORBIMED, ADVISORS LLC | 10% Owner | 普通株式 | 売却 | 3,000 | $10.86 |
| 2012-02-28 | ORBIMED, ADVISORS LLC | 10% Owner | 普通株式 | 売却 | 10,000 | $11.12 |
| 2012-02-28 | ORBIMED, ADVISORS LLC | 10% Owner | 普通株式 | 売却 | 100 | $11.12 |
| 2012-02-27 | ORBIMED, ADVISORS LLC | 10% Owner | 普通株式 | 売却 | 28,700 | $11.05 |
| 2012-02-27 | ORBIMED, ADVISORS LLC | 10% Owner | 普通株式 | 売却 | 300 | $11.05 |
| 2012-02-03 | ORBIMED, ADVISORS LLC | 10% Owner | 普通株式 | 売却 | 49,500 | $10.79 |
| 2012-02-03 | ORBIMED, ADVISORS LLC | 10% Owner | 普通株式 | 売却 | 500 | $10.79 |
| 2012-02-02 | ORBIMED, ADVISORS LLC | 10% Owner | 普通株式 | 売却 | 23,100 | $10.85 |
| 2012-02-02 | ORBIMED, ADVISORS LLC | 10% Owner | 普通株式 | 売却 | 200 | $10.85 |
| 2012-02-01 | ORBIMED, ADVISORS LLC | 10% Owner | 普通株式 | 売却 | 69,300 | $11.01 |
| 2012-02-01 | ORBIMED, ADVISORS LLC | 10% Owner | 普通株式 | 売却 | 700 | $11.01 |
| 2012-01-03 | PRATT, JOHN | General Manager, San Diego | ストックオプション | 購入 | 30,000 | $0.00 |
| 2011-11-21 | MIDDLETON, FRED A | Director, 10% Owner | 普通株式 | 購入 | 10,000 | $6.50 |
| 2011-11-21 | HBM, BIOVENTURES CAYMAN LTD | 10% Owner | 普通株式 | 購入 | 307,692 | $6.50 |
| 2011-11-21 | WICKI, ANDREAS | Director | 普通株式 | 購入 | 307,692 | $6.50 |
| 2011-11-21 | PACE, GARY W | Director | 普通株式 | 購入 | 7,692 | $6.50 |
売上・収益性
売上高（直近12ヶ月）
$72,641万ドル
一株あたり売上高（直近12ヶ月）
$16.30
売上総利益（直近12ヶ月）
$45,935万ドル
営業利益（EBITDA：減価償却前）
$12,432万ドル
利益率
0.97%
営業利益率（直近12ヶ月）
-1.17%
配当・収入
配当金額（1株あたり）
$None
配当利回り
0%
支払日
None
権利落ち日
None
バリュエーション指標
株価収益率（PER）
153.19倍
実績PER
153.19倍
予想PER
10.44倍
株価収益成長率（PEG）
11.21
株価売上高倍率（直近12ヶ月）
1.452倍
株価純資産倍率 (PBR)
1.482倍
1株当たり純資産（BPS）
$16.86
企業価値倍率（EV）
EV/売上高倍率
1.661倍
EV/EBITDA倍率
9.85倍
投資リターン
総資産利益率（直近12ヶ月）
1.48%
自己資本利益率（直近12ヶ月）
0.96%
リターン分析
| 日数 | リターンレンジ | リターン中央値 | 累積リターン | 分散（バリアンス） | 標準偏差 | 最大下落率 | 最大下落期間 | SPYとの相関係数 | ||
|---|---|---|---|---|---|---|---|---|---|---|
| 15日間 | -3.3517% | 4.2432% | 0.8511% | 7.3263% | 0.0004380606751879413 | 0.020929899072569397 | -3.3517% | 1日 | -0.43417444537411526 | |
| 30日間 | -3.3517% | 4.2432% | 0.7844% | 9.5402% | 0.0003918596975240346 | 0.019795446383550803 | -3.3517% | 1日 | -0.1843144651612361 | |
| 90日間 | -3.762% | 4.4557% | 0.7116% | 24.0993% | 0.0004480484385378368 | 0.02116715471049042 | -9.2924% | 5日 | 0.049580884887514755 |
損益計算書
会計期末日
2025-12-31
報告通貨
USD
売上高・粗利益
売上原価
営業経費
営業利益・税引前指標
売上高
$726,411,000
粗利益
$519,374,000
売上コスト
$207,037,000
商品・サービス原価
$207,037,000
販売管理費
$368,759,000
研究開発
$117,312,000
運営コスト
$491,271,000
減価償却
$None
減価償却・償却費
$91,023,000
営業利益
$28,103,000
営業利益EBIT
$28,103,000
償却前営業利益EBITA
$119,126,000
税引前利益
$16,874,000
利息・投資・その他営業外項目
税金関連
当期純・包括利益
純投資収益
$None
純金利収入
$5,286,000
利息収入
$22,732,000
金利コスト
$17,446,000
利息・債務コスト
$None
非利息収益
$None
営業外収益（その他）
$None
法人税等
$9,840,000
継続事業純利益
$7,034,000
純利益
$7,034,000
税引後包括利益
$None
貸借対照表
会計期末日
2025-12-31
報告通貨
USD
総資産
$1,264,917,000
現金及び現金同等物
$158,545,000
現金及び短期投資
$158,545,000
短期投資
$79,879,000
在庫資産
$152,863,000
流動売掛金（純額）
$124,069,000
その他流動資産
$32,618,000
流動資産合計
$547,974,000
有形固定資産
$None
減価償却累計額（PPE）
$None
無形資産
$368,100,000
無形資産（のれん除く）
$368,100,000
のれん（無形資産）
$20,214,000
投資
$None
長期投資
$None
その他固定資産
$None
固定資産合計
$716,943,000
総負債
$571,806,000
買掛金（短期）
$15,150,000
前受金
$None
流動債務
$None
短期借入金
$9,839,000
固定長期負債
$None
その他流動負債
$95,601,000
流動負債合計
$120,590,000
リース債務
$46,015,000
長期債務
$372,189,000
長期債務（流動外）
$None
短期・長期借入金合計
$454,380,000
その他固定負債
$38,638,000
固定負債合計
$451,216,000
純資産
$693,111,000
自己株式（金庫株）
$None
利益剰余金
-$199,322,000
普通株式
$48,000
発行済株式数（普通株）
$45,042,000
キャッシュフロー計算書
会計期末日
2025-12-31
報告通貨
USD
損益計算・収益性
営業活動
投資活動
損益
$None
純利益
$7,034,000
営業キャッシュフロー
$151,994,000
営業活動による支払い
$None
営業活動によるキャッシュフロー
$None
営業活動に関連する負債の増減額
$None
営業活動に関連する資産の増減額
$None
売掛金の増減額
$None
在庫資産の増減額
-$27,567,000
減価償却・減耗費・償却費
$91,023,000
投資活動によるキャッシュフロー
$99,481,000
設備投資
$15,333,000
財務活動
資金・為替照合
財務活動によるキャッシュフロー
-$369,627,000
短期融資回収金
$None
自社株買い支出（普通株）
$None
自社株買い支出（優先株）
$None
自社株買い支出
$None
配当支払い（普通株）
$None
配当支払い（優先株）
$None
配当支払い
$None
資金調達（普通株）
$None
資金調達（優先株）
$None
資金調達（長期債・資本証券）
$None
自社株売却による収益
$None
自社株再取得による収益
-$148,328,000
現金及び現金同等物の増減額
$None
為替レートの変動による増減額
$None
発行済株式数
広告パネル
スポンサー紹介
本物のネイティブ講師による
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