SGMO
サンガモ・セラピューティクス
Sangamo Therapeutics Inc
株価・概要
$0.14
0.02 (13.2550%)
06:00AM 2026/05/02 (JST)
NASDAQ | USD
52週間レンジ
0.118
0.766
昨夜レンジ
0.12
0.14
前日終値
$0.12
出来高（数量）
17,421,394
ベータ値
1.503
50日移動平均値
$0.32
200日移動平均値
$0.46
1株あたりの利益（EPS）
-0.44
予想PER（株価収益率）
0.395
配当金
$None
配当利回り
0%
インサイダー保有率
1.764%
機関投資家保有率
14.932%
SGMO - 会社概要
サンガモ・セラピューティクス社は、カリフォルニア州ブリスベンに本社を置く臨床段階のバイオテクノロジー企業であり、革新的なゲノム医薬品の開発を専門としています。遺伝子治療、細胞治療、ゲノム編集、ゲノム制御における独自のプラットフォーム技術を活用し、サンガモは満たされていない医療ニーズに対応し、患者の治療成果の向上に取り組んでいます。同社の最先端研究は、遺伝性および後天性疾患の治療法の進展に焦点を当てており、急速に進化するゲノム医療分野において重要な役割を果たしています。
本社住所
501 CANAL BLVD, RICHMOND, CA, UNITED STATES, 94804
企業サイト
https://www.sangamo.com
会計年度終了
December
最新四半期
2025-12-31
利益・成長性
1株あたりの利益（EPS）
-$0.44
希薄化後1株当たり利益EPS（直近12ヶ月）
-$0.44
四半期利益成長率（前年比）
0.0%
四半期売上成長率（前年比）
88.4%
アナリスト予想・評価
目標株価
$3.75
強気
0
買い
2
ホールド
2
売り
0
弱気
0
EPS（1株当たり純利益）
| 7日前 | 30日前 | 60日前 | 90日前 | 予想レンジ | |||
|---|---|---|---|---|---|---|---|
配当履歴
| 権利落ち日 | 配当宣言日 | 権利確定日 | 配当金支払日 | 配当金額 |
|---|
株式分割
| 効力発生日 | 分割比率 |
|---|
インサイダーの売却・購入履歴
| 自社株取引日 | 役員・従業員名 | 役員・従業員の役職 | 株式の種類 | 売却／購入 | 株数 | 株価 |
|---|---|---|---|---|---|---|
| 2026-04-01 | DUBOIS-STRINGFELLOW, NATHALIE | SVP-CHIEF DEVELOPMENT OFFICER | ストックオプション | 購入 | 800,000 | $0.00 |
| 2026-04-01 | JAIN, NIKUNJ | Principal Accounting Officer | ストックオプション | 購入 | 225,000 | $0.00 |
| 2026-04-01 | DAVIS, GREGORY D | Head of Research & Technology | ストックオプション | 購入 | 225,000 | $0.00 |
| 2026-04-01 | MACRAE, SANDY | Director, PRESIDENT, CEO AND DIRECTOR | ストックオプション | 購入 | 2,500,000 | $0.00 |
| 2026-04-01 | WILLOUGHBY, SCOTT B. | SVP, CHIEF LEGAL OFFICER, SECY | ストックオプション | 購入 | 800,000 | $0.00 |
| 2026-02-25 | WILLOUGHBY, SCOTT B. | SVP, CHIEF LEGAL OFFICER, SECY | 普通株式 | 売却 | 12,354 | $0.47 |
| 2026-02-25 | MACRAE, SANDY | Director, PRESIDENT, CEO AND DIRECTOR | 普通株式 | 売却 | 33,637 | $0.47 |
| 2026-02-25 | JAIN, NIKUNJ | Principal Accounting Officer | 普通株式 | 売却 | 5,119 | $0.47 |
| 2026-02-25 | DUBOIS-STRINGFELLOW, NATHALIE | SVP-CHIEF DEVELOPMENT OFFICER | 普通株式 | 売却 | 12,354 | $0.47 |
| 2026-02-25 | DAVIS, GREGORY D | Head of Research & Technology | 普通株式 | 売却 | 5,119 | $0.47 |
| 2026-02-24 | DUBOIS-STRINGFELLOW, NATHALIE | SVP-CHIEF DEVELOPMENT OFFICER | 普通株式 | 売却 | 2,063 | $0.47 |
| 2026-02-24 | MACRAE, SANDY | Director, PRESIDENT, CEO AND DIRECTOR | 普通株式 | 売却 | 5,291 | $0.47 |
| 2026-02-24 | WILLOUGHBY, SCOTT B. | SVP, CHIEF LEGAL OFFICER, SECY | 普通株式 | 売却 | 1,650 | $0.47 |
| 2026-02-24 | JAIN, NIKUNJ | Principal Accounting Officer | 普通株式 | 売却 | 666 | $0.47 |
| 2026-02-24 | DAVIS, GREGORY D | Head of Research & Technology | 普通株式 | 売却 | 832 | $0.47 |
| 2026-01-22 | WILLOUGHBY, SCOTT B. | SVP, CHIEF LEGAL OFFICER, SECY | 普通株式 | 売却 | 36,676 | $0.40 |
| 2026-01-22 | DURAIBABU, PRATHYUSHA | PRINCIPAL FINANCIAL OFFICER | 普通株式 | 売却 | 36,676 | $0.40 |
| 2026-01-22 | JAIN, NIKUNJ | Principal Accounting Officer | 普通株式 | 売却 | 7,721 | $0.40 |
| 2026-01-22 | DUBOIS-STRINGFELLOW, NATHALIE | SVP-CHIEF DEVELOPMENT OFFICER | 普通株式 | 売却 | 36,676 | $0.40 |
| 2026-01-22 | DAVIS, GREGORY D | Head of Research & Technology | 普通株式 | 売却 | 7,721 | $0.40 |
| 2026-01-22 | MACRAE, SANDY | Director, PRESIDENT, CEO AND DIRECTOR | 普通株式 | 売却 | 102,950 | $0.40 |
| 2025-11-24 | WILLOUGHBY, SCOTT B. | SVP, CHIEF LEGAL OFFICER, SECY | 普通株式 | 売却 | 2,035 | $0.42 |
| 2025-11-24 | JAIN, NIKUNJ | Principal Accounting Officer | 普通株式 | 売却 | 578 | $0.42 |
| 2025-11-24 | MACRAE, SANDY | Director, PRESIDENT, CEO AND DIRECTOR | 普通株式 | 売却 | 7,488 | $0.42 |
| 2025-11-24 | DURAIBABU, PRATHYUSHA | PRINCIPAL FINANCIAL OFFICER | 普通株式 | 売却 | 2,544 | $0.42 |
| 2025-11-24 | DUBOIS-STRINGFELLOW, NATHALIE | SVP-CHIEF DEVELOPMENT OFFICER | 普通株式 | 売却 | 2,544 | $0.42 |
| 2025-11-24 | DAVIS, GREGORY D | Head of Research & Technology | 普通株式 | 売却 | 723 | $0.42 |
| 2025-10-22 | DAVIS, GREGORY D | Head of Research & Technology | 普通株式 | 売却 | 6,708 | $0.66 |
| 2025-10-22 | JAIN, NIKUNJ | Principal Accounting Officer | 普通株式 | 売却 | 6,708 | $0.66 |
| 2025-10-22 | MACRAE, SANDY | Director, PRESIDENT, CEO AND DIRECTOR | 普通株式 | 売却 | 126,950 | $0.66 |
| 2025-10-22 | WILLOUGHBY, SCOTT B. | SVP, CHIEF LEGAL OFFICER, SECY | 普通株式 | 売却 | 44,122 | $0.66 |
| 2025-10-22 | DUBOIS-STRINGFELLOW, NATHALIE | SVP-CHIEF DEVELOPMENT OFFICER | 普通株式 | 売却 | 43,741 | $0.66 |
| 2025-10-22 | DURAIBABU, PRATHYUSHA | PRINCIPAL FINANCIAL OFFICER | 普通株式 | 売却 | 45,225 | $0.66 |
| 2025-08-24 | DURAIBABU, PRATHYUSHA | SVP, CHIEF FINANCIAL OFFICER | 普通株式 | 売却 | 1,792 | $0.59 |
| 2025-08-24 | MACRAE, SANDY | Director, PRESIDENT, CEO AND DIRECTOR | 普通株式 | 売却 | 7,488 | $0.59 |
| 2025-08-24 | DAVIS, GREGORY D | Head of Research & Technology | 普通株式 | 売却 | 723 | $0.59 |
| 2025-08-24 | WILLOUGHBY, SCOTT B. | SVP, CHIEF LEGAL OFFICER, SECY | 普通株式 | 売却 | 1,434 | $0.59 |
| 2025-08-24 | DUBOIS-STRINGFELLOW, NATHALIE | SVP-CHIEF DEVELOPMENT OFFICER | 普通株式 | 売却 | 1,792 | $0.59 |
| 2025-07-22 | DURAIBABU, PRATHYUSHA | SVP, CHIEF FINANCIAL OFFICER | 普通株式 | 売却 | 31,866 | $0.48 |
| 2025-07-22 | DAVIS, GREGORY D | Head of Research & Technology | 普通株式 | 売却 | 6,708 | $0.48 |
| 2025-07-22 | DUBOIS-STRINGFELLOW, NATHALIE | SVP-CHIEF DEVELOPMENT OFFICER | 普通株式 | 売却 | 31,866 | $0.48 |
| 2025-07-22 | WILLOUGHBY, SCOTT B. | SVP, CHIEF LEGAL OFFICER, SECY | 普通株式 | 売却 | 31,866 | $0.48 |
| 2025-07-22 | MACRAE, SANDY | Director, PRESIDENT, CEO AND DIRECTOR | 普通株式 | 売却 | 126,950 | $0.48 |
| 2025-06-12 | HORN, MARGARET A | Director | ストックオプション | 購入 | 50,000 | $0.00 |
| 2025-06-12 | SMITH, KAREN L. | Director | ストックオプション | 購入 | 50,000 | $0.00 |
| 2025-06-12 | PARKER, H STEWART | Director | 普通株式 | 購入 | 25,000 | $0.00 |
| 2025-06-12 | MEYERS, JAMES R | Director | ストックオプション | 購入 | 50,000 | $0.00 |
| 2025-06-12 | HILLAN, KENNETH J. | Director | 普通株式 | 購入 | 25,000 | $0.00 |
| 2025-06-12 | HILLAN, KENNETH J. | Director | ストックオプション | 購入 | 50,000 | $0.00 |
| 2025-06-12 | MARKELS, JOHN | Director | 普通株式 | 購入 | 25,000 | $0.00 |
| 2025-06-12 | MARKELS, JOHN | Director | ストックオプション | 購入 | 50,000 | $0.00 |
| 2025-06-12 | CAREY, ROBERT | Director | 普通株式 | 購入 | 25,000 | $0.00 |
| 2025-06-12 | CAREY, ROBERT | Director | ストックオプション | 購入 | 50,000 | $0.00 |
| 2025-06-12 | HORN, MARGARET A | Director | 普通株式 | 購入 | 25,000 | $0.00 |
| 2025-06-12 | PARKER, H STEWART | Director | ストックオプション | 購入 | 50,000 | $0.00 |
| 2025-06-12 | MEYERS, JAMES R | Director | 普通株式 | 購入 | 25,000 | $0.00 |
| 2025-06-12 | BEERS, COURTNEY | Director | 普通株式 | 購入 | 25,000 | $0.00 |
| 2025-06-12 | BEERS, COURTNEY | Director | ストックオプション | 購入 | 50,000 | $0.00 |
| 2025-06-12 | SMITH, KAREN L. | Director | 普通株式 | 購入 | 25,000 | $0.00 |
| 2025-05-24 | WILLOUGHBY, SCOTT B. | SVP, CHIEF LEGAL OFFICER, SECY | 普通株式 | 売却 | 1,433 | $0.47 |
| 2025-05-24 | DUBOIS-STRINGFELLOW, NATHALIE | SVP-CHIEF DEVELOPMENT OFFICER | 普通株式 | 売却 | 1,792 | $0.47 |
| 2025-05-24 | DURAIBABU, PRATHYUSHA | SVP, CHIEF FINANCIAL OFFICER | 普通株式 | 売却 | 1,792 | $0.47 |
| 2025-05-24 | MACRAE, SANDY | Director, PRESIDENT, CEO AND DIRECTOR | 普通株式 | 売却 | 7,488 | $0.47 |
| 2025-05-24 | DAVIS, GREGORY D | Head of Research & Technology | 普通株式 | 売却 | 723 | $0.47 |
| 2025-04-22 | WILLOUGHBY, SCOTT B. | SVP, GEN. COUNSEL & SECRETARY | 普通株式 | 売却 | 31,866 | $0.78 |
| 2025-04-22 | MACRAE, SANDY | Director, PRESIDENT, CEO AND DIRECTOR | 普通株式 | 売却 | 126,950 | $0.78 |
| 2025-04-22 | DUBOIS-STRINGFELLOW, NATHALIE | SVP-CHIEF DEVELOPMENT OFFICER | 普通株式 | 売却 | 31,866 | $0.78 |
| 2025-04-22 | DAVIS, GREGORY D | Head of Research & Technology | 普通株式 | 売却 | 6,708 | $0.78 |
| 2025-04-22 | DURAIBABU, PRATHYUSHA | SVP, CHIEF FINANCIAL OFFICER | 普通株式 | 売却 | 31,866 | $0.78 |
| 2025-02-25 | DUBOIS-STRINGFELLOW, NATHALIE | SVP-CHIEF DEVELOPMENT OFFICER | 普通株式 | 購入 | 120,000 | $0.00 |
| 2025-02-25 | DUBOIS-STRINGFELLOW, NATHALIE | SVP-CHIEF DEVELOPMENT OFFICER | ストックオプション | 購入 | 560,000 | $0.00 |
| 2025-02-25 | WILLOUGHBY, SCOTT B. | SVP, GEN. COUNSEL & SECRETARY | 普通株式 | 売却 | 1,375 | $0.96 |
| 2025-02-25 | WILLOUGHBY, SCOTT B. | SVP, GEN. COUNSEL & SECRETARY | 普通株式 | 購入 | 120,000 | $0.00 |
| 2025-02-25 | WILLOUGHBY, SCOTT B. | SVP, GEN. COUNSEL & SECRETARY | ストックオプション | 購入 | 560,000 | $0.00 |
| 2025-02-25 | DURAIBABU, PRATHYUSHA | SVP, CHIEF FINANCIAL OFFICER | 普通株式 | 売却 | 1,375 | $0.96 |
| 2025-02-25 | DURAIBABU, PRATHYUSHA | SVP, CHIEF FINANCIAL OFFICER | 普通株式 | 購入 | 120,000 | $0.00 |
| 2025-02-25 | DURAIBABU, PRATHYUSHA | SVP, CHIEF FINANCIAL OFFICER | ストックオプション | 購入 | 560,000 | $0.00 |
| 2025-02-25 | MACRAE, SANDY | Director, PRESIDENT, CEO AND DIRECTOR | 普通株式 | 売却 | 10,663 | $0.96 |
| 2025-02-25 | MACRAE, SANDY | Director, PRESIDENT, CEO AND DIRECTOR | 普通株式 | 購入 | 375,000 | $0.00 |
| 2025-02-25 | MACRAE, SANDY | Director, PRESIDENT, CEO AND DIRECTOR | ストックオプション | 購入 | 1,750,000 | $0.00 |
| 2025-02-25 | DAVIS, GREGORY D | Head of Research & Technology | 普通株式 | 売却 | 507 | $0.96 |
| 2025-02-25 | DAVIS, GREGORY D | Head of Research & Technology | 普通株式 | 購入 | 49,726 | $0.00 |
| 2025-02-25 | DAVIS, GREGORY D | Head of Research & Technology | ストックオプション | 購入 | 99,454 | $0.00 |
| 2025-02-25 | DUBOIS-STRINGFELLOW, NATHALIE | SVP-CHIEF DEVELOPMENT OFFICER | 普通株式 | 売却 | 1,513 | $0.96 |
| 2025-02-24 | MACRAE, SANDY | Director, PRESIDENT, CEO AND DIRECTOR | 普通株式 | 売却 | 7,488 | $1.00 |
| 2025-02-24 | DUBOIS-STRINGFELLOW, NATHALIE | SVP-CHIEF DEVELOPMENT OFFICER | 普通株式 | 売却 | 1,792 | $1.00 |
| 2025-02-24 | DAVIS, GREGORY D | Head of Research & Technology | 普通株式 | 売却 | 705 | $1.00 |
| 2025-02-24 | WILLOUGHBY, SCOTT B. | SVP, GEN. COUNSEL & SECRETARY | 普通株式 | 売却 | 1,434 | $1.00 |
| 2025-02-24 | DURAIBABU, PRATHYUSHA | SVP, CHIEF FINANCIAL OFFICER | 普通株式 | 売却 | 1,792 | $1.00 |
| 2025-01-22 | DUBOIS-STRINGFELLOW, NATHALIE | SVP-CHIEF DEVELOPMENT OFFICER | 普通株式 | 売却 | 129,593 | $1.15 |
| 2025-01-22 | DAVIS, GREGORY D | Head of Research & Technology | 普通株式 | 売却 | 30,456 | $1.15 |
| 2025-01-22 | DURAIBABU, PRATHYUSHA | SVP, CHIEF FINANCIAL OFFICER | 普通株式 | 売却 | 129,242 | $1.15 |
| 2025-01-22 | MACRAE, SANDY | Director, PRESIDENT, CEO AND DIRECTOR | 普通株式 | 売却 | 412,584 | $1.15 |
| 2025-01-22 | WILLOUGHBY, SCOTT B. | SVP, GEN. COUNSEL & SECRETARY | 普通株式 | 売却 | 129,549 | $1.15 |
| 2024-11-25 | DAVIS, GREGORY D | Head of Research & Technology | 普通株式 | 売却 | 505 | $1.94 |
| 2024-11-25 | WILLOUGHBY, SCOTT B. | SVP, GEN. COUNSEL & SECRETARY | 普通株式 | 売却 | 1,371 | $1.94 |
| 2024-11-25 | DUBOIS-STRINGFELLOW, NATHALIE | SVP-CHIEF DEVELOPMENT OFFICER | 普通株式 | 売却 | 1,508 | $1.94 |
| 2024-11-25 | MACRAE, SANDY | Director, PRESIDENT, CEO AND DIRECTOR | 普通株式 | 売却 | 10,642 | $1.94 |
| 2024-11-25 | DURAIBABU, PRATHYUSHA | SVP, CHIEF FINANCIAL OFFICER | 普通株式 | 売却 | 1,371 | $1.94 |
| 2024-11-24 | DUBOIS-STRINGFELLOW, NATHALIE | SVP-CHIEF DEVELOPMENT OFFICER | 普通株式 | 売却 | 1,787 | $1.88 |
| 2024-11-24 | DURAIBABU, PRATHYUSHA | SVP, CHIEF FINANCIAL OFFICER | 普通株式 | 売却 | 1,787 | $1.88 |
| 2024-11-24 | WILLOUGHBY, SCOTT B. | SVP, GEN. COUNSEL & SECRETARY | 普通株式 | 売却 | 1,430 | $1.88 |
| 2024-11-24 | MACRAE, SANDY | Director, PRESIDENT, CEO AND DIRECTOR | 普通株式 | 売却 | 7,473 | $1.88 |
| 2024-11-24 | DAVIS, GREGORY D | Head of Research & Technology | 普通株式 | 売却 | 721 | $1.88 |
| 2024-08-25 | DURAIBABU, PRATHYUSHA | SVP, CHIEF FINANCIAL OFFICER | 普通株式 | 売却 | 1,371 | $0.86 |
| 2024-08-25 | MACRAE, SANDY | Director, PRESIDENT, CEO AND DIRECTOR | 普通株式 | 売却 | 7,492 | $0.86 |
| 2024-08-25 | WILLOUGHBY, SCOTT B. | SVP, GEN. COUNSEL & SECRETARY | 普通株式 | 売却 | 1,371 | $0.86 |
| 2024-08-25 | POOLER, AMY | VP, HEAD OF RESEARCH | 普通株式 | 売却 | 493 | $0.86 |
| 2024-08-25 | DUBOIS-STRINGFELLOW, NATHALIE | SVP-CHIEF DEVELOPMENT OFFICER | 普通株式 | 売却 | 1,508 | $0.86 |
| 2024-08-24 | DUBOIS-STRINGFELLOW, NATHALIE | SVP-CHIEF DEVELOPMENT OFFICER | 普通株式 | 売却 | 1,787 | $0.86 |
| 2024-08-24 | WILLOUGHBY, SCOTT B. | SVP, GEN. COUNSEL & SECRETARY | 普通株式 | 売却 | 1,430 | $0.86 |
| 2024-08-24 | DURAIBABU, PRATHYUSHA | SVP, CHIEF FINANCIAL OFFICER | 普通株式 | 売却 | 1,787 | $0.86 |
| 2024-08-24 | POOLER, AMY | VP, HEAD OF RESEARCH | 普通株式 | 売却 | 703 | $0.86 |
| 2024-08-24 | MACRAE, SANDY | Director, PRESIDENT, CEO AND DIRECTOR | 普通株式 | 売却 | 5,261 | $0.86 |
| 2024-08-13 | WILLOUGHBY, SCOTT B. | SVP, GEN. COUNSEL & SECRETARY | 普通株式 | 売却 | 892 | $0.98 |
| 2024-06-11 | DURAIBABU, PRATHYUSHA | SVP, CHIEF FINANCIAL OFFICER | 普通株式 | 売却 | 892 | $0.61 |
| 2024-06-04 | BEERS, COURTNEY | Director | ストックオプション | 購入 | 50,000 | $0.00 |
| 2024-06-04 | SMITH, KAREN L. | Director | 普通株式 | 購入 | 25,000 | $0.00 |
| 2024-06-04 | SMITH, KAREN L. | Director | ストックオプション | 購入 | 50,000 | $0.00 |
| 2024-06-04 | PARKER, H STEWART | Director | 普通株式 | 購入 | 25,000 | $0.00 |
| 2024-06-04 | PARKER, H STEWART | Director | ストックオプション | 購入 | 50,000 | $0.00 |
| 2024-06-04 | MEYERS, JAMES R | Director | 普通株式 | 購入 | 25,000 | $0.00 |
| 2024-06-04 | MEYERS, JAMES R | Director | ストックオプション | 購入 | 50,000 | $0.00 |
| 2024-06-04 | MARKELS, JOHN | Director | 普通株式 | 購入 | 25,000 | $0.00 |
| 2024-06-04 | MARKELS, JOHN | Director | ストックオプション | 購入 | 50,000 | $0.00 |
| 2024-06-04 | HORN, MARGARET A | Director | 普通株式 | 購入 | 25,000 | $0.00 |
| 2024-06-04 | HORN, MARGARET A | Director | ストックオプション | 購入 | 50,000 | $0.00 |
| 2024-06-04 | HILLAN, KENNETH J. | Director | 普通株式 | 購入 | 25,000 | $0.00 |
| 2024-06-04 | HILLAN, KENNETH J. | Director | ストックオプション | 購入 | 50,000 | $0.00 |
| 2024-06-04 | CAREY, ROBERT | Director | 普通株式 | 購入 | 25,000 | $0.00 |
| 2024-06-04 | CAREY, ROBERT | Director | ストックオプション | 購入 | 50,000 | $0.00 |
| 2024-06-04 | BEERS, COURTNEY | Director | 普通株式 | 購入 | 25,000 | $0.00 |
| 2024-05-25 | MACRAE, SANDY | Director, PRESIDENT, CEO AND DIRECTOR | 普通株式 | 売却 | 7,492 | $0.60 |
| 2024-05-25 | DUBOIS-STRINGFELLOW, NATHALIE | SVP-CHIEF DEVELOPMENT OFFICER | 普通株式 | 売却 | 1,508 | $0.60 |
| 2024-05-25 | WILLOUGHBY, SCOTT B. | SVP, GEN. COUNSEL & SECRETARY | 普通株式 | 売却 | 1,336 | $0.60 |
| 2024-05-25 | POOLER, AMY | VP, HEAD OF RESEARCH | 普通株式 | 売却 | 493 | $0.60 |
| 2024-05-25 | DURAIBABU, PRATHYUSHA | SVP, CHIEF FINANCIAL OFFICER | 普通株式 | 売却 | 1,371 | $0.60 |
| 2024-05-24 | DUBOIS-STRINGFELLOW, NATHALIE | SVP-CHIEF DEVELOPMENT OFFICER | 普通株式 | 売却 | 1,787 | $0.60 |
| 2024-05-24 | MACRAE, SANDY | Director, PRESIDENT, CEO AND DIRECTOR | 普通株式 | 売却 | 5,261 | $0.60 |
| 2024-05-24 | DURAIBABU, PRATHYUSHA | SVP, CHIEF FINANCIAL OFFICER | 普通株式 | 売却 | 1,787 | $0.60 |
| 2024-05-24 | POOLER, AMY | VP, HEAD OF RESEARCH | 普通株式 | 売却 | 702 | $0.60 |
| 2024-05-24 | WILLOUGHBY, SCOTT B. | SVP, GEN. COUNSEL & SECRETARY | 普通株式 | 売却 | 1,400 | $0.60 |
| 2024-02-25 | MACRAE, SANDY | Director, PRESIDENT, CEO AND DIRECTOR | 普通株式 | 売却 | 24,157 | $1.13 |
| 2024-02-25 | DUBOIS-STRINGFELLOW, NATHALIE | SVP-CHIEF DEVELOPMENT OFFICER | 普通株式 | 売却 | 5,010 | $1.13 |
| 2024-02-25 | POOLER, AMY | VP, HEAD OF RESEARCH | 普通株式 | 売却 | 2,459 | $1.13 |
| 2024-02-25 | DURAIBABU, PRATHYUSHA | SVP, CHIEF FINANCIAL OFFICER | 普通株式 | 売却 | 3,453 | $1.13 |
| 2024-02-25 | WILLOUGHBY, SCOTT B. | SVP, GEN. COUNSEL & SECRETARY | 普通株式 | 売却 | 3,453 | $1.13 |
| 2024-02-24 | MACRAE, SANDY | Director, PRESIDENT, CEO AND DIRECTOR | 普通株式 | 売却 | 16,115 | $1.13 |
| 2024-02-24 | DURAIBABU, PRATHYUSHA | SVP, CHIEF FINANCIAL OFFICER | 普通株式 | 売却 | 5,474 | $1.13 |
| 2024-02-24 | DUBOIS-STRINGFELLOW, NATHALIE | SVP-CHIEF DEVELOPMENT OFFICER | 普通株式 | 売却 | 5,474 | $1.13 |
| 2024-02-24 | WILLOUGHBY, SCOTT B. | SVP, GEN. COUNSEL & SECRETARY | 普通株式 | 売却 | 4,379 | $1.13 |
| 2024-02-24 | POOLER, AMY | VP, HEAD OF RESEARCH | 普通株式 | 売却 | 2,209 | $1.13 |
| 2024-01-22 | WILLOUGHBY, SCOTT B. | SVP, GEN. COUNSEL & SECRETARY | 普通株式 | 購入 | 712,500 | $0.00 |
| 2024-01-22 | MACRAE, SANDY | Director, PRESIDENT, CEO AND DIRECTOR | 普通株式 | 購入 | 2,000,000 | $0.00 |
| 2024-01-22 | DUBOIS-STRINGFELLOW, NATHALIE | SVP-CHIEF DEVELOPMENT OFFICER | 普通株式 | 購入 | 712,500 | $0.00 |
| 2024-01-22 | DURAIBABU, PRATHYUSHA | SVP, CHIEF FINANCIAL OFFICER | 普通株式 | 購入 | 712,500 | $0.00 |
| 2024-01-22 | POOLER, AMY | VP, HEAD OF RESEARCH | 普通株式 | 購入 | 150,000 | $0.00 |
| 2023-11-25 | FONTENOT, JASON D. | SVP, Chief Scientific Officer | 普通株式 | 売却 | 1,030 | $0.38 |
| 2023-11-25 | MACRAE, SANDY | Director, President, CEO and Director | 普通株式 | 売却 | 10,411 | $0.38 |
| 2023-11-25 | MCCLUNG, DAVID MARK | EVP, Chief Operating Officer | 普通株式 | 売却 | 1,925 | $0.38 |
| 2023-11-25 | WILLOUGHBY, SCOTT B. | SVP, Gen. Counsel & Secretary | 普通株式 | 売却 | 1,329 | $0.38 |
| 2023-11-25 | DURAIBABU, PRATHYUSHA | SVP, Chief Financial Officer | 普通株式 | 売却 | 1,329 | $0.38 |
| 2023-11-25 | POOLER, AMY | VP, Head of Research | 普通株式 | 売却 | 490 | $0.38 |
| 2023-11-25 | DUBOIS-STRINGFELLOW, NATHALIE | SVP-Chief Development Officer | 普通株式 | 売却 | 1,462 | $0.38 |
| 2023-09-26 | BIOGEN, INC. | 10% Owner | 普通株式 | 売却 | 6,000,000 | $0.50 |
| 2023-08-25 | DURAIBABU, PRATHYUSHA | SVP, Chief Financial Officer | 普通株式 | 売却 | 1,329 | $0.77 |
| 2023-08-25 | MCCLUNG, DAVID MARK | EVP, Chief Operating Officer | 普通株式 | 売却 | 1,925 | $0.77 |
| 2023-08-25 | FONTENOT, JASON D. | SVP, Chief Scientific Officer | 普通株式 | 売却 | 1,029 | $0.77 |
| 2023-08-25 | MACRAE, SANDY | Director, President, CEO and Director | 普通株式 | 売却 | 10,411 | $0.77 |
| 2023-08-25 | DUBOIS-STRINGFELLOW, NATHALIE | SVP-Chief Development Officer | 普通株式 | 売却 | 1,462 | $0.77 |
| 2023-08-25 | WILLOUGHBY, SCOTT B. | SVP, Gen. Counsel & Secretary | 普通株式 | 売却 | 1,329 | $0.77 |
| 2023-08-13 | WILLOUGHBY, SCOTT B. | SVP, Gen. Counsel & Secretary | 普通株式 | 売却 | 864 | $1.08 |
| 2023-06-25 | MCCLUNG, DAVID MARK | EVP, Chief Operating Officer | 普通株式 | 売却 | 11,528 | $1.19 |
| 2023-06-11 | DURAIBABU, PRATHYUSHA | SVP, Chief Financial Officer | 普通株式 | 売却 | 864 | $1.19 |
| 2023-06-01 | PARKER, H STEWART | Director | ストックオプション | 購入 | 27,750 | $0.00 |
| 2023-06-01 | SMITH, KAREN L. | Director | ストックオプション | 購入 | 27,750 | $0.00 |
| 2023-06-01 | MEYERS, JAMES R | Director | ストックオプション | 購入 | 27,750 | $0.00 |
| 2023-06-01 | HILLAN, KENNETH J. | Director | 普通株式 | 購入 | 13,900 | $0.00 |
| 2023-06-01 | HILLAN, KENNETH J. | Director | ストックオプション | 購入 | 27,750 | $0.00 |
| 2023-06-01 | CAREY, ROBERT | Director | 普通株式 | 購入 | 13,900 | $0.00 |
| 2023-06-01 | CAREY, ROBERT | Director | ストックオプション | 購入 | 27,750 | $0.00 |
| 2023-06-01 | BEERS, COURTNEY | Director | 普通株式 | 購入 | 13,900 | $0.00 |
| 2023-06-01 | MARKELS, JOHN | Director | 普通株式 | 購入 | 13,900 | $0.00 |
| 2023-06-01 | BEERS, COURTNEY | Director | ストックオプション | 購入 | 27,750 | $0.00 |
| 2023-06-01 | SMITH, KAREN L. | Director | 普通株式 | 購入 | 13,900 | $0.00 |
| 2023-06-01 | HORN, MARGARET A | Director | ストックオプション | 購入 | 27,750 | $0.00 |
| 2023-06-01 | HORN, MARGARET A | Director | 普通株式 | 購入 | 13,900 | $0.00 |
| 2023-06-01 | MARKELS, JOHN | Director | ストックオプション | 購入 | 27,750 | $0.00 |
| 2023-06-01 | MEYERS, JAMES R | Director | 普通株式 | 購入 | 13,900 | $0.00 |
| 2023-06-01 | PARKER, H STEWART | Director | 普通株式 | 購入 | 13,900 | $0.00 |
| 2023-05-25 | MACRAE, SANDY | Director, President, CEO and Director | 普通株式 | 売却 | 10,411 | $1.33 |
| 2023-05-25 | WILLOUGHBY, SCOTT B. | SVP, Gen. Counsel & Secretary | 普通株式 | 売却 | 1,328 | $1.33 |
| 2023-05-25 | RAMELMEIER, ROLF ANDREW | EVP, Technical Operations | 普通株式 | 売却 | 1,750 | $1.33 |
| 2023-05-25 | MCCLUNG, DAVID MARK | EVP, Chief Operating Officer | 普通株式 | 売却 | 1,925 | $1.33 |
| 2023-05-25 | DUBOIS-STRINGFELLOW, NATHALIE | SVP-Chief Development Officer | 普通株式 | 売却 | 1,462 | $1.33 |
| 2023-05-25 | FONTENOT, JASON D. | SVP, Chief Scientific Officer | 普通株式 | 売却 | 1,029 | $1.33 |
| 2023-05-25 | DURAIBABU, PRATHYUSHA | SVP, Chief Financial Officer | 普通株式 | 売却 | 1,328 | $1.33 |
| 2023-04-24 | WILLOUGHBY, SCOTT B. | SVP, Gen. Counsel & Secretary | 普通株式 | 売却 | 3,977 | $1.65 |
| 2023-03-25 | DURAIBABU, PRATHYUSHA | SVP, Chief Financial Officer | 普通株式 | 売却 | 345 | $1.66 |
| 2023-02-25 | WILLOUGHBY, SCOTT B. | SVP, Gen. Counsel & Secretary | 普通株式 | 売却 | 5,128 | $2.66 |
| 2023-02-25 | FONTENOT, JASON D. | SVP, Chief Scientific Officer | 普通株式 | 売却 | 6,559 | $2.66 |
| 2023-02-25 | DURAIBABU, PRATHYUSHA | SVP, Chief Financial Officer | 普通株式 | 売却 | 7,030 | $2.66 |
| 2023-02-25 | RAMELMEIER, ROLF ANDREW | EVP, Technical Operations | 普通株式 | 売却 | 15,618 | $2.66 |
| 2023-02-25 | DUBOIS-STRINGFELLOW, NATHALIE | SVP-Chief Development Officer | 普通株式 | 売却 | 9,834 | $2.66 |
| 2023-02-25 | MCCLUNG, DAVID MARK | EVP, Chief Operating Officer | 普通株式 | 売却 | 9,745 | $2.66 |
| 2023-02-25 | MACRAE, SANDY | Director, President, CEO and Director | 普通株式 | 売却 | 54,767 | $2.66 |
| 2023-02-24 | DUBOIS-STRINGFELLOW, NATHALIE | SVP-Chief Development Officer | ストックオプション | 購入 | 249,375 | $0.00 |
| 2023-02-24 | MACRAE, SANDY | Director, President, CEO and Director | ストックオプション | 購入 | 734,050 | $0.00 |
| 2023-02-24 | MACRAE, SANDY | Director, President, CEO and Director | 普通株式 | 購入 | 157,300 | $0.00 |
| 2023-02-24 | DURAIBABU, PRATHYUSHA | SVP, Chief Financial Officer | ストックオプション | 購入 | 249,375 | $0.00 |
| 2023-02-24 | DURAIBABU, PRATHYUSHA | SVP, Chief Financial Officer | 普通株式 | 購入 | 53,438 | $0.00 |
| 2023-02-24 | FONTENOT, JASON D. | SVP, Chief Scientific Officer | ストックオプション | 購入 | 199,500 | $0.00 |
| 2023-02-24 | FONTENOT, JASON D. | SVP, Chief Scientific Officer | 普通株式 | 購入 | 42,750 | $0.00 |
| 2023-02-24 | DUBOIS-STRINGFELLOW, NATHALIE | SVP-Chief Development Officer | 普通株式 | 購入 | 53,438 | $0.00 |
| 2023-02-24 | MCCLUNG, DAVID MARK | EVP, Chief Operating Officer | ストックオプション | 購入 | 262,500 | $0.00 |
| 2023-02-24 | MCCLUNG, DAVID MARK | EVP, Chief Operating Officer | 普通株式 | 購入 | 56,250 | $0.00 |
| 2023-02-24 | RAMELMEIER, ROLF ANDREW | EVP, Technical Operations | ストックオプション | 購入 | 210,000 | $0.00 |
| 2023-02-24 | RAMELMEIER, ROLF ANDREW | EVP, Technical Operations | 普通株式 | 購入 | 45,000 | $0.00 |
| 2023-02-24 | WILLOUGHBY, SCOTT B. | SVP, Gen. Counsel & Secretary | ストックオプション | 購入 | 199,500 | $0.00 |
| 2023-02-24 | WILLOUGHBY, SCOTT B. | SVP, Gen. Counsel & Secretary | 普通株式 | 購入 | 42,750 | $0.00 |
| 2022-12-15 | BEERS, COURTNEY | Director | ストックオプション | 購入 | 37,500 | $0.00 |
| 2022-12-15 | BEERS, COURTNEY | Director | 普通株式 | 購入 | 18,750 | $0.00 |
| 2022-12-15 | HORN, MARGARET A | Director | ストックオプション | 購入 | 37,500 | $0.00 |
| 2022-12-15 | HORN, MARGARET A | Director | 普通株式 | 購入 | 18,750 | $0.00 |
| 2022-08-30 | BIOGEN, INC. | 10% Owner | 普通株式 | 売却 | 100,000 | $5.27 |
| 2022-08-29 | BIOGEN, INC. | 10% Owner | 普通株式 | 売却 | 400,000 | $5.33 |
| 2022-08-13 | WILLOUGHBY, SCOTT B. | SVP, Gen. Counsel & Secretary | 普通株式 | 売却 | 864 | $6.33 |
| 2022-06-25 | MCCLUNG, DAVID MARK | EVP, Chief Operating Officer | 普通株式 | 売却 | 11,525 | $4.31 |
| 2022-06-11 | DURAIBABU, PRATHYUSHA | Vice President, Finance | 普通株式 | 売却 | 842 | $3.76 |
| 2022-06-11 | DURAIBABU, PRATHYUSHA | SVP, Chief Financial Officer | 普通株式 | 売却 | 864 | $3.76 |
| 2022-06-03 | MARKELS, JOHN | Director | 普通株式 | 購入 | 6,784 | $3.69 |
| 2022-06-01 | PARKER, H STEWART | Director | 普通株式 | 購入 | 5,000 | $3.60 |
| 2022-04-29 | WILLOUGHBY, SCOTT B. | SVP, Gen. Counsel & Secretary | 普通株式 | 売却 | 140 | $4.15 |
| 2022-04-25 | DURAIBABU, PRATHYUSHA | Vice President, Finance | 普通株式 | 売却 | 662 | $4.83 |
| 2022-04-25 | FONTENOT, JASON D. | SVP, Chief Scientific Officer | 普通株式 | 売却 | 826 | $4.83 |
| 2022-04-24 | WILLOUGHBY, SCOTT B. | SVP, Gen. Counsel & Secretary | 普通株式 | 売却 | 3,976 | $4.70 |
| 2022-03-25 | DURAIBABU, PRATHYUSHA | Vice President, Finance | 普通株式 | 売却 | 345 | $5.75 |
| 2022-02-25 | SCHOTT, ROBERT J. | SVP, Head of Development | 普通株式 | 購入 | 41,000 | $0.00 |
| 2022-02-25 | MACRAE, SANDY | Director, President, CEO and Director | ストックオプション | 購入 | 604,800 | $0.00 |
| 2022-02-25 | ZAKRZEWSKI, JOSEPH S | Director | 普通株式 | 購入 | 12,500 | $0.00 |
| 2022-02-25 | ZAKRZEWSKI, JOSEPH S | Director | ストックオプション | 購入 | 25,000 | $0.00 |
| 2022-02-25 | SMITH, KAREN L. | Director | 普通株式 | 購入 | 12,500 | $0.00 |
| 2022-02-25 | SMITH, KAREN L. | Director | ストックオプション | 購入 | 25,000 | $0.00 |
| 2022-02-25 | RAMASASTRY, SAIRA | Director | 普通株式 | 購入 | 12,500 | $0.00 |
| 2022-02-25 | RAMELMEIER, ROLF ANDREW | EVP, Technical Operations | ストックオプション | 購入 | 145,800 | $0.00 |
| 2022-02-25 | CAREY, ROBERT | Director | ストックオプション | 購入 | 25,000 | $0.00 |
| 2022-02-25 | CAREY, ROBERT | Director | 普通株式 | 購入 | 12,500 | $0.00 |
| 2022-02-25 | HILLAN, KENNETH J. | Director | 普通株式 | 購入 | 12,500 | $0.00 |
| 2022-02-25 | MARKELS, JOHN | Director | ストックオプション | 購入 | 25,000 | $0.00 |
| 2022-02-25 | MACRAE, SANDY | Director, President, CEO and Director | 普通株式 | 購入 | 224,000 | $0.00 |
| 2022-02-25 | MACRAE, SANDY | Director, President, CEO and Director | 普通株式 | 売却 | 49,890 | $5.90 |
| 2022-02-25 | MCCLUNG, DAVID MARK | EVP, Chief Operating Officer | 普通株式 | 売却 | 4,610 | $5.90 |
| 2022-02-25 | DURAIBABU, PRATHYUSHA | Vice President, Finance | ストックオプション | 購入 | 110,700 | $0.00 |
| 2022-02-25 | DURAIBABU, PRATHYUSHA | Vice President, Finance | 普通株式 | 購入 | 41,000 | $0.00 |
| 2022-02-25 | DURAIBABU, PRATHYUSHA | Vice President, Finance | 普通株式 | 売却 | 3,474 | $5.90 |
| 2022-02-25 | FONTENOT, JASON D. | SVP, Chief Scientific Officer | ストックオプション | 購入 | 121,770 | $0.00 |
| 2022-02-25 | FONTENOT, JASON D. | SVP, Chief Scientific Officer | 普通株式 | 購入 | 45,100 | $0.00 |
| 2022-02-25 | FONTENOT, JASON D. | SVP, Chief Scientific Officer | 普通株式 | 売却 | 6,248 | $5.90 |
| 2022-02-25 | RAMELMEIER, ROLF ANDREW | EVP, Technical Operations | 普通株式 | 購入 | 54,000 | $0.00 |
| 2022-02-25 | RAMELMEIER, ROLF ANDREW | EVP, Technical Operations | 普通株式 | 売却 | 12,388 | $5.90 |
| 2022-02-25 | SCHOTT, ROBERT J. | SVP, Head of Development | ストックオプション | 購入 | 110,700 | $0.00 |
| 2022-02-25 | RAMASASTRY, SAIRA | Director | ストックオプション | 購入 | 25,000 | $0.00 |
| 2022-02-25 | PARKER, H STEWART | Director | 普通株式 | 購入 | 12,500 | $0.00 |
| 2022-02-25 | PARKER, H STEWART | Director | ストックオプション | 購入 | 25,000 | $0.00 |
| 2022-02-25 | MEYERS, JAMES R | Director | 普通株式 | 購入 | 12,500 | $0.00 |
| 2022-02-25 | MEYERS, JAMES R | Director | ストックオプション | 購入 | 25,000 | $0.00 |
| 2022-02-25 | MARKELS, JOHN | Director | 普通株式 | 購入 | 12,500 | $0.00 |
| 2022-02-25 | HILLAN, KENNETH J. | Director | ストックオプション | 購入 | 25,000 | $0.00 |
| 2022-02-25 | MCCLUNG, DAVID MARK | EVP, Chief Operating Officer | ストックオプション | 購入 | 160,380 | $0.00 |
| 2022-02-25 | MCCLUNG, DAVID MARK | EVP, Chief Operating Officer | 普通株式 | 購入 | 59,400 | $0.00 |
| 2022-02-25 | WILLOUGHBY, SCOTT B. | SVP, Gen. Counsel & Secretary | ストックオプション | 購入 | 110,700 | $0.00 |
| 2022-02-25 | WILLOUGHBY, SCOTT B. | SVP, Gen. Counsel & Secretary | 普通株式 | 購入 | 41,000 | $0.00 |
| 2022-02-25 | WILLOUGHBY, SCOTT B. | SVP, Gen. Counsel & Secretary | 普通株式 | 売却 | 1,566 | $5.90 |
| 2022-02-12 | SCHOTT, ROBERT J. | SVP, Head of Development | 普通株式 | 売却 | 5,463 | $5.76 |
| 2021-12-28 | BIOGEN, INC. | 10% Owner | 普通株式 | 売却 | 2,764 | $8.51 |
| 2021-12-27 | BIOGEN, INC. | 10% Owner | 普通株式 | 売却 | 600 | $8.56 |
| 2021-12-23 | BIOGEN, INC. | 10% Owner | 普通株式 | 売却 | 81,187 | $8.55 |
| 2021-12-09 | BIOGEN, INC. | 10% Owner | 普通株式 | 売却 | 23,660 | $8.56 |
| 2021-12-08 | BIOGEN, INC. | 10% Owner | 普通株式 | 売却 | 75,814 | $8.64 |
| 2021-12-07 | BIOGEN, INC. | 10% Owner | 普通株式 | 売却 | 52,178 | $8.52 |
| 2021-12-02 | BIOGEN, INC. | 10% Owner | 普通株式 | 売却 | 1,874 | $8.51 |
| 2021-12-01 | BIOGEN, INC. | 10% Owner | 普通株式 | 売却 | 730 | $8.52 |
| 2021-11-26 | BIOGEN, INC. | 10% Owner | 普通株式 | 売却 | 28,884 | $8.60 |
| 2021-10-29 | WILLOUGHBY, SCOTT B. | SVP, Gen. Counsel & Secretary | 普通株式 | 売却 | 140 | $8.12 |
| 2021-08-13 | WILLOUGHBY, SCOTT B. | SVP, Gen. Counsel & Secretary | 普通株式 | 購入 | 7,500 | $0.00 |
| 2021-08-13 | WILLOUGHBY, SCOTT B. | SVP, Gen. Counsel & Secretary | ストックオプション | 購入 | 15,000 | $0.00 |
| 2021-06-25 | MCCLUNG, DAVID MARK | EVP, Chief Business Officer | 普通株式 | 売却 | 11,525 | $12.02 |
| 2021-06-11 | DURAIBABU, PRATHYUSHA | SVP, CFO, PFO and PAO | ストックオプション | 購入 | 15,000 | $0.00 |
| 2021-06-11 | DURAIBABU, PRATHYUSHA | SVP, CFO, PFO and PAO | 普通株式 | 購入 | 7,500 | $0.00 |
| 2021-04-25 | DURAIBABU, PRATHYUSHA | VP, PFO and PAO | 普通株式 | 売却 | 662 | $11.71 |
| 2021-04-25 | FONTENOT, JASON D. | SVP, Chief Scientific Officer | 普通株式 | 売却 | 811 | $11.71 |
| 2021-03-25 | DURAIBABU, PRATHYUSHA | VP, PFO and PAO | 普通株式 | 売却 | 345 | $12.27 |
| 2021-03-23 | LOEB, GARY | EVP, General Counsel & Sec. | ストックオプション | 売却 | 11,981 | $0.00 |
| 2021-03-23 | LOEB, GARY | EVP, General Counsel & Sec. | 普通株式 | 購入 | 11,981 | $11.02 |
| 2021-03-23 | LOEB, GARY | EVP, General Counsel & Sec. | 普通株式 | 売却 | 11,981 | $13.10 |
| 2021-03-23 | LOEB, GARY | EVP, General Counsel & Sec. | 普通株式 | 売却 | 5,000 | $13.18 |
| 2021-03-23 | LOEB, GARY | EVP, General Counsel & Sec. | 普通株式 | 売却 | 543 | $13.17 |
| 2021-02-25 | RAMELMEIER, ROLF ANDREW | EVP, Technical Operations | ストックオプション | 購入 | 80,000 | $0.00 |
| 2021-02-25 | MCCLUNG, DAVID MARK | EVP, Chief Business Officer | ストックオプション | 購入 | 80,000 | $0.00 |
| 2021-02-25 | LOEB, GARY | EVP, General Counsel & Sec. | 普通株式 | 売却 | 5,762 | $11.19 |
| 2021-02-25 | LOEB, GARY | EVP, General Counsel & Sec. | 普通株式 | 購入 | 44,000 | $0.00 |
| 2021-02-25 | LOEB, GARY | EVP, General Counsel & Sec. | ストックオプション | 購入 | 88,000 | $0.00 |
| 2021-02-25 | MACRAE, SANDY | Director, President and CEO | 普通株式 | 売却 | 35,311 | $11.19 |
| 2021-02-25 | MACRAE, SANDY | Director, President and CEO | 普通株式 | 購入 | 138,375 | $0.00 |
| 2021-02-25 | MACRAE, SANDY | Director, President and CEO | ストックオプション | 購入 | 276,750 | $0.00 |
| 2021-02-25 | ZAKRZEWSKI, JOSEPH S | Director | 普通株式 | 購入 | 8,200 | $0.00 |
| 2021-02-25 | HILLAN, KENNETH J. | Director | 普通株式 | 購入 | 8,200 | $0.00 |
| 2021-02-25 | RAMELMEIER, ROLF ANDREW | EVP, Technical Operations | 普通株式 | 売却 | 7,779 | $11.19 |
| 2021-02-25 | DURAIBABU, PRATHYUSHA | VP, PFO and PAO | 普通株式 | 売却 | 1,863 | $11.19 |
| 2021-02-25 | DURAIBABU, PRATHYUSHA | VP, PFO and PAO | 普通株式 | 購入 | 13,750 | $0.00 |
| 2021-02-25 | DURAIBABU, PRATHYUSHA | VP, PFO and PAO | ストックオプション | 購入 | 27,500 | $0.00 |
| 2021-02-25 | DURAIBABU, PRATHYUSHA | VP Principal Acct. Officer | 普通株式 | 売却 | 1,863 | $11.19 |
| 2021-02-25 | DURAIBABU, PRATHYUSHA | VP Principal Acct. Officer | 普通株式 | 購入 | 13,750 | $0.00 |
| 2021-02-25 | DURAIBABU, PRATHYUSHA | VP Principal Acct. Officer | ストックオプション | 購入 | 27,500 | $0.00 |
| 2021-02-25 | RAMELMEIER, ROLF ANDREW | EVP, Technical Operations | 普通株式 | 購入 | 40,000 | $0.00 |
| 2021-02-25 | CAREY, ROBERT | Director | ストックオプション | 購入 | 16,400 | $0.00 |
| 2021-02-25 | CAREY, ROBERT | Director | 普通株式 | 購入 | 8,200 | $0.00 |
| 2021-02-25 | HILLAN, KENNETH J. | Director | ストックオプション | 購入 | 16,400 | $0.00 |
| 2021-02-25 | MARKELS, JOHN | Director | ストックオプション | 購入 | 16,400 | $0.00 |
| 2021-02-25 | MARKELS, JOHN | Director | 普通株式 | 購入 | 8,200 | $0.00 |
| 2021-02-25 | MEYERS, JAMES R | Director | ストックオプション | 購入 | 16,400 | $0.00 |
| 2021-02-25 | MEYERS, JAMES R | Director | 普通株式 | 購入 | 8,200 | $0.00 |
| 2021-02-25 | PARKER, H STEWART | Director | ストックオプション | 購入 | 16,400 | $0.00 |
| 2021-02-25 | PARKER, H STEWART | Director | 普通株式 | 購入 | 8,200 | $0.00 |
| 2021-02-25 | RAMASASTRY, SAIRA | Director | ストックオプション | 購入 | 16,400 | $0.00 |
| 2021-02-25 | RAMASASTRY, SAIRA | Director | 普通株式 | 購入 | 8,200 | $0.00 |
| 2021-02-25 | SMITH, KAREN L. | Director | ストックオプション | 購入 | 16,400 | $0.00 |
| 2021-02-25 | SMITH, KAREN L. | Director | 普通株式 | 購入 | 8,200 | $0.00 |
| 2021-02-25 | ZAKRZEWSKI, JOSEPH S | Director | ストックオプション | 購入 | 16,400 | $0.00 |
| 2021-02-25 | MCCLUNG, DAVID MARK | EVP, Chief Business Officer | 普通株式 | 購入 | 40,000 | $0.00 |
| 2021-02-12 | SCHOTT, ROBERT J. | SVP, Head of Development | 普通株式 | 購入 | 40,000 | $0.00 |
| 2021-02-12 | SCHOTT, ROBERT J. | SVP, Head of Development | ストックオプション | 購入 | 80,000 | $0.00 |
| 2021-01-24 | MACRAE, SANDY | Director, President and CEO | 普通株式 | 売却 | 3,977 | $14.95 |
| 2020-12-31 | RAMELMEIER, ROLF ANDREW | EVP, Technical Operations | 普通株式 | 売却 | 2,464 | $16.74 |
| 2020-12-24 | RAMELMEIER, ROLF ANDREW | EVP, Technical Operations | 普通株式 | 売却 | 3,331 | $18.13 |
| 2020-12-17 | RAMASASTRY, SAIRA | Director | 普通株式 | 購入 | 10,000 | $5.99 |
| 2020-12-17 | RAMASASTRY, SAIRA | Director | 普通株式 | 売却 | 10,000 | $13.27 |
| 2020-12-17 | RAMASASTRY, SAIRA | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2020-11-25 | LEE, SUNG | EVP, Chief Financial Officer | 普通株式 | 売却 | 5,042 | $9.77 |
| 2020-09-09 | HILLAN, KENNETH J. | Director | ストックオプション | 購入 | 30,000 | $0.00 |
| 2020-09-09 | HILLAN, KENNETH J. | Director | 普通株式 | 購入 | 15,000 | $0.00 |
| 2020-07-03 | BOISSEL, STEPHANE | EVP, Corp. Strategy | 普通株式 | 売却 | 1 | $0.00 |
| 2020-06-25 | MCCLUNG, DAVID MARK | EVP, Chief Business Officer | 普通株式 | 購入 | 100,000 | $0.00 |
| 2020-06-25 | MCCLUNG, DAVID MARK | EVP, Chief Business Officer | ストックオプション | 購入 | 200,000 | $0.00 |
| 2020-06-04 | BOISSEL, STEPHANE | EVP, Corp. Strategy | 普通株式 | 売却 | 1 | $0.00 |
| 2020-06-04 | BOISSEL, STEPHANE | EVP, Corp. Strategy | 普通株式 | 購入 | 14,907 | $ |
| 2020-06-04 | BOISSEL, STEPHANE | EVP, Corp. Strategy | 普通株式 | 売却 | 14,907 | $11.23 |
| 2020-05-18 | ZAKRZEWSKI, JOSEPH S | Director | 普通株式 | 購入 | 2,500 | $0.00 |
| 2020-05-18 | CAREY, ROBERT | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2020-05-18 | CAREY, ROBERT | Director | 普通株式 | 購入 | 10,000 | $0.00 |
| 2020-05-18 | DILLY, STEPHEN GEORGE | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2020-05-18 | DILLY, STEPHEN GEORGE | Director | 普通株式 | 購入 | 10,000 | $0.00 |
| 2020-05-18 | MEYERS, JAMES R | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2020-05-18 | PARKER, H STEWART | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2020-05-18 | ZAKRZEWSKI, JOSEPH S | Director | 普通株式 | 購入 | 10,000 | $0.00 |
| 2020-05-18 | MEYERS, JAMES R | Director | 普通株式 | 購入 | 10,000 | $0.00 |
| 2020-05-18 | MEYERS, JAMES R | Director | 普通株式 | 購入 | 2,500 | $0.00 |
| 2020-05-18 | CAREY, ROBERT | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2020-05-18 | CAREY, ROBERT | Director | 普通株式 | 購入 | 2,500 | $0.00 |
| 2020-05-18 | DILLY, STEPHEN GEORGE | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2020-05-18 | DILLY, STEPHEN GEORGE | Director | 普通株式 | 購入 | 2,500 | $0.00 |
| 2020-05-18 | RAMASASTRY, SAIRA | Director | 普通株式 | 購入 | 10,000 | $0.00 |
| 2020-05-18 | SMITH, KAREN L. | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2020-05-18 | SMITH, KAREN L. | Director | 普通株式 | 購入 | 10,000 | $0.00 |
| 2020-05-18 | RAMASASTRY, SAIRA | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2020-05-18 | RAMASASTRY, SAIRA | Director | 普通株式 | 購入 | 2,500 | $0.00 |
| 2020-05-18 | PARKER, H STEWART | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2020-05-18 | PARKER, H STEWART | Director | 普通株式 | 購入 | 10,000 | $0.00 |
| 2020-05-18 | RAMASASTRY, SAIRA | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2020-05-18 | SMITH, KAREN L. | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2020-05-18 | SMITH, KAREN L. | Director | 普通株式 | 購入 | 2,500 | $0.00 |
| 2020-05-18 | ZAKRZEWSKI, JOSEPH S | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2020-05-18 | MEYERS, JAMES R | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2020-05-18 | ZAKRZEWSKI, JOSEPH S | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2020-05-18 | PARKER, H STEWART | Director | 普通株式 | 購入 | 2,500 | $0.00 |
| 2020-05-09 | BOISSEL, STEPHANE | EVP, Corp. Strategy | 普通株式 | 売却 | 1 | $0.00 |
| 2020-04-25 | DURAIBABU, PRATHYUSHA | VP Principal Acct. Officer | 普通株式 | 売却 | 647 | $8.32 |
| 2020-03-25 | DURAIBABU, PRATHYUSHA | VP Principal Acct. Officer | 普通株式 | 購入 | 3,000 | $0.00 |
| 2020-03-19 | DILLY, STEPHEN GEORGE | Director | ストックオプション | 売却 | 35,000 | $0.00 |
| 2020-03-19 | DILLY, STEPHEN GEORGE | Director | 普通株式 | 購入 | 35,000 | $5.42 |
| 2020-03-19 | DILLY, STEPHEN GEORGE | Director | 普通株式 | 売却 | 35,000 | $6.00 |
| 2020-03-18 | PARKER, H STEWART | Director | 普通株式 | 購入 | 3,000 | $5.20 |
| 2020-03-17 | ZAKRZEWSKI, JOSEPH S | Director | 普通株式 | 購入 | 5,000 | $4.99 |
| 2020-03-16 | DILLY, STEPHEN GEORGE | Director | 普通株式 | 購入 | 15,000 | $5.42 |
| 2020-03-16 | DILLY, STEPHEN GEORGE | Director | 普通株式 | 売却 | 15,000 | $6.02 |
| 2020-03-16 | DILLY, STEPHEN GEORGE | Director | ストックオプション | 売却 | 15,000 | $0.00 |
| 2020-03-13 | ZAKRZEWSKI, JOSEPH S | Director | 普通株式 | 購入 | 5,000 | $5.67 |
| 2020-03-12 | ZAKRZEWSKI, JOSEPH S | Director | 普通株式 | 購入 | 15,000 | $6.31 |
| 2020-02-25 | MACRAE, SANDY | Director, President and CEO | 普通株式 | 購入 | 168,750 | $0.00 |
| 2020-02-25 | MACRAE, SANDY | Director, President and CEO | ストックオプション | 購入 | 337,500 | $0.00 |
| 2020-02-25 | LOEB, GARY | EVP, General Counsel & Sec. | ストックオプション | 購入 | 100,000 | $0.00 |
| 2020-02-25 | WOOLFSON, ADRIAN | EVP Research & Development | 普通株式 | 購入 | 50,000 | $0.00 |
| 2020-02-25 | WOOLFSON, ADRIAN | EVP Research & Development | ストックオプション | 購入 | 100,000 | $0.00 |
| 2020-02-25 | DURAIBABU, PRATHYUSHA | VP Principal Acct. Officer | 普通株式 | 購入 | 16,500 | $0.00 |
| 2020-02-25 | DURAIBABU, PRATHYUSHA | VP Principal Acct. Officer | ストックオプション | 購入 | 33,000 | $0.00 |
| 2020-02-25 | RAMELMEIER, ROLF ANDREW | EVP, Technical Operations | 普通株式 | 売却 | 1,703 | $6.80 |
| 2020-02-25 | RAMELMEIER, ROLF ANDREW | EVP, Technical Operations | 普通株式 | 購入 | 55,000 | $0.00 |
| 2020-02-25 | RAMELMEIER, ROLF ANDREW | EVP, Technical Operations | ストックオプション | 購入 | 110,000 | $0.00 |
| 2020-02-25 | LOEB, GARY | EVP, General Counsel & Sec. | 普通株式 | 購入 | 500,000 | $0.00 |
| 2020-02-25 | LEE, SUNG | EVP, Chief Financial Officer | 普通株式 | 購入 | 50,000 | $0.00 |
| 2020-02-25 | LEE, SUNG | EVP, Chief Financial Officer | ストックオプション | 購入 | 100,500 | $0.00 |
| 2020-02-25 | BOISSEL, STEPHANE | EVP, Corp. Strategy | 普通株式 | 売却 | 2,384 | $6.80 |
| 2020-02-25 | BOISSEL, STEPHANE | EVP, Corp. Strategy | 普通株式 | 購入 | 55,000 | $0.00 |
| 2020-02-25 | BOISSEL, STEPHANE | EVP, Corp. Strategy | ストックオプション | 購入 | 110,000 | $0.00 |
| 2020-02-25 | LOEB, GARY | EVP, General Counsel & Sec. | 普通株式 | 購入 | 50,000 | $0.00 |
| 2020-02-25 | MACRAE, SANDY | Director, President and CEO | 普通株式 | 売却 | 7,264 | $6.80 |
| 2020-02-11 | MARKELS, JOHN | Director | 普通株式 | 購入 | 5,000 | $0.00 |
| 2020-02-11 | MARKELS, JOHN | Director | ストックオプション | 購入 | 30,000 | $0.00 |
| 2020-01-24 | MACRAE, SANDY | Director, President and CEO | 普通株式 | 売却 | 4,283 | $7.50 |
| 2019-11-25 | LEE, SUNG | EVP, Chief Financial Officer | 普通株式 | 購入 | 43,750 | $0.00 |
| 2019-11-25 | LEE, SUNG | EVP, Chief Financial Officer | ストックオプション | 購入 | 262,000 | $0.00 |
| 2019-11-22 | MEYERS, JAMES R | Director | ストックオプション | 購入 | 30,000 | $0.00 |
| 2019-11-22 | MEYERS, JAMES R | Director | 普通株式 | 購入 | 5,000 | $0.00 |
| 2019-08-23 | LOEB, GARY | EVP, General Counsel & Sec. | ストックオプション | 購入 | 250,000 | $0.00 |
| 2019-08-12 | BOISSEL, STEPHANE | EVP, Corp. Strat. & Int. CFO | 普通株式 | 購入 | 11,137 | $ |
| 2019-08-12 | BOISSEL, STEPHANE | EVP, Corp. Strat. & Int. CFO | 普通株式 | 売却 | 11,137 | $11.23 |
| 2019-08-12 | BOISSEL, STEPHANE | EVP, Corp. Strat. & Int. CFO | 普通株式 | 売却 | 1 | $0.00 |
| 2019-06-10 | SMITH, KAREN L. | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2019-06-10 | SMITH, KAREN L. | Director | 普通株式 | 購入 | 2,500 | $0.00 |
| 2019-06-10 | ZAKRZEWSKI, JOSEPH S | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2019-06-10 | ZAKRZEWSKI, JOSEPH S | Director | 普通株式 | 購入 | 2,500 | $0.00 |
| 2019-06-10 | RAMASASTRY, SAIRA | Director | 普通株式 | 購入 | 2,500 | $0.00 |
| 2019-06-10 | RAMASASTRY, SAIRA | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2019-06-10 | PARKER, H STEWART | Director | 普通株式 | 購入 | 2,500 | $0.00 |
| 2019-06-10 | PARKER, H STEWART | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2019-06-10 | DILLY, STEPHEN GEORGE | Director | 普通株式 | 購入 | 2,500 | $0.00 |
| 2019-06-10 | DILLY, STEPHEN GEORGE | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2019-06-10 | CAREY, ROBERT | Director | 普通株式 | 購入 | 2,500 | $0.00 |
| 2019-06-10 | CAREY, ROBERT | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2019-05-15 | YI, KATHY | EVP & Chief Financial Officer | 普通株式 | 売却 | 5,000 | $10.00 |
| 2019-05-15 | YI, KATHY | EVP & Chief Financial Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2019-05-15 | YI, KATHY | EVP & Chief Financial Officer | 普通株式 | 購入 | 5,000 | $4.55 |
| 2019-04-15 | YI, KATHY | EVP & Chief Financial Officer | 普通株式 | 売却 | 5,000 | $12.11 |
| 2019-04-15 | YI, KATHY | EVP & Chief Financial Officer | 普通株式 | 購入 | 5,000 | $4.55 |
| 2019-04-15 | YI, KATHY | EVP & Chief Financial Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2019-03-15 | YI, KATHY | EVP & Chief Financial Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2019-03-15 | YI, KATHY | EVP & Chief Financial Officer | 普通株式 | 売却 | 5,000 | $10.00 |
| 2019-03-15 | YI, KATHY | EVP & Chief Financial Officer | 普通株式 | 購入 | 5,000 | $4.55 |
| 2019-03-01 | YI, KATHY | EVP & Chief Financial Officer | 普通株式 | 購入 | 5,000 | $4.55 |
| 2019-03-01 | YI, KATHY | EVP & Chief Financial Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2019-03-01 | YI, KATHY | EVP & Chief Financial Officer | 普通株式 | 売却 | 5,000 | $10.00 |
| 2019-02-25 | TURNER, HEATHER D | EVP, General Counsel & Sec. | 普通株式 | 購入 | 19,250 | $0.00 |
| 2019-02-25 | BOISSEL, STEPHANE | EVP, Corporate Strategy | ストックオプション | 購入 | 105,000 | $0.00 |
| 2019-02-25 | TURNER, HEATHER D | EVP, General Counsel & Sec. | ストックオプション | 購入 | 115,500 | $0.00 |
| 2019-02-25 | YI, KATHY | EVP & Chief Financial Officer | ストックオプション | 購入 | 115,500 | $0.00 |
| 2019-02-25 | BOISSEL, STEPHANE | EVP, Corporate Strategy | 普通株式 | 購入 | 17,500 | $0.00 |
| 2019-02-25 | WOOLFSON, ADRIAN | EVP, Research and Development | ストックオプション | 購入 | 250,000 | $0.00 |
| 2019-02-25 | MACRAE, SANDY | Director, President and CEO | ストックオプション | 購入 | 379,500 | $0.00 |
| 2019-02-25 | MACRAE, SANDY | Director, President and CEO | 普通株式 | 購入 | 63,250 | $0.00 |
| 2019-02-25 | YI, KATHY | EVP & Chief Financial Officer | 普通株式 | 購入 | 19,250 | $0.00 |
| 2019-01-24 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | 普通株式 | 売却 | 834 | $11.10 |
| 2019-01-24 | YI, KATHY | SVP & Chief Financial Officer | 普通株式 | 売却 | 988 | $11.10 |
| 2019-01-15 | YI, KATHY | SVP & Chief Financial Officer | 普通株式 | 売却 | 5,000 | $11.04 |
| 2019-01-15 | YI, KATHY | SVP & Chief Financial Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2019-01-15 | YI, KATHY | SVP & Chief Financial Officer | 普通株式 | 購入 | 5,000 | $4.55 |
| 2019-01-07 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | 普通株式 | 購入 | 5,000 | $3.20 |
| 2019-01-07 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | 普通株式 | 売却 | 5,000 | $12.33 |
| 2019-01-07 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2018-12-17 | YI, KATHY | SVP & Chief Financial Officer | 普通株式 | 購入 | 5,000 | $4.55 |
| 2018-12-17 | YI, KATHY | SVP & Chief Financial Officer | 普通株式 | 売却 | 5,000 | $11.44 |
| 2018-12-17 | YI, KATHY | SVP & Chief Financial Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2018-12-06 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | 普通株式 | 購入 | 5,000 | $3.20 |
| 2018-12-06 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | 普通株式 | 売却 | 5,000 | $11.49 |
| 2018-12-06 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2018-11-27 | BOISSEL, STEPHANE | EVP, Corp. Strat. & Int. CFO | 普通株式 | 売却 | 4 | $0.00 |
| 2018-11-27 | BOISSEL, STEPHANE | EVP, Corp. Strat. & Int. CFO | 普通株式 | 購入 | 4 | $0.00 |
| 2018-11-23 | BOISSEL, STEPHANE | EVP, Corporate Strategy | ストックオプション | 購入 | 283,523 | $0.00 |
| 2018-11-15 | YI, KATHY | SVP & Chief Financial Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2018-11-15 | YI, KATHY | SVP & Chief Financial Officer | 普通株式 | 売却 | 5,000 | $10.00 |
| 2018-11-15 | YI, KATHY | SVP & Chief Financial Officer | 普通株式 | 購入 | 5,000 | $4.55 |
| 2018-11-14 | PARKER, H STEWART | Director | 普通株式 | 購入 | 2,000 | $9.00 |
| 2018-11-06 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | 普通株式 | 売却 | 5,000 | $13.73 |
| 2018-11-06 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2018-11-06 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | 普通株式 | 購入 | 5,000 | $3.20 |
| 2018-10-15 | YI, KATHY | SVP & Chief Financial Officer | 普通株式 | 購入 | 5,000 | $4.55 |
| 2018-10-15 | YI, KATHY | SVP & Chief Financial Officer | 普通株式 | 売却 | 5,000 | $13.97 |
| 2018-10-15 | YI, KATHY | SVP & Chief Financial Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2018-10-08 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | 普通株式 | 売却 | 5,000 | $14.55 |
| 2018-10-08 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2018-10-08 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | 普通株式 | 購入 | 5,000 | $3.20 |
| 2018-09-17 | YI, KATHY | SVP & Chief Financial Officer | 普通株式 | 売却 | 5,000 | $14.66 |
| 2018-09-17 | YI, KATHY | SVP & Chief Financial Officer | 普通株式 | 購入 | 5,000 | $4.55 |
| 2018-09-17 | YI, KATHY | SVP & Chief Financial Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2018-09-07 | JEFFS, ROGER | Director | 普通株式 | 購入 | 7,408 | $13.56 |
| 2018-09-07 | PARKER, H STEWART | Director | 普通株式 | 購入 | 2,000 | $13.52 |
| 2018-09-06 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2018-09-06 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | 普通株式 | 購入 | 5,000 | $3.20 |
| 2018-09-06 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | 普通株式 | 売却 | 5,000 | $14.17 |
| 2018-08-16 | YI, KATHY | SVP & Chief Financial Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2018-08-16 | YI, KATHY | SVP & Chief Financial Officer | 普通株式 | 売却 | 5,000 | $15.39 |
| 2018-08-16 | YI, KATHY | SVP & Chief Financial Officer | 普通株式 | 購入 | 5,000 | $4.55 |
| 2018-08-06 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2018-08-06 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | 普通株式 | 売却 | 5,000 | $13.45 |
| 2018-08-06 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | 普通株式 | 購入 | 5,000 | $3.20 |
| 2018-07-16 | YI, KATHY | SVP & Chief Financial Officer | 普通株式 | 購入 | 5,000 | $4.55 |
| 2018-07-16 | YI, KATHY | SVP & Chief Financial Officer | 普通株式 | 売却 | 5,000 | $14.77 |
| 2018-07-16 | YI, KATHY | SVP & Chief Financial Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2018-07-06 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2018-07-06 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | 普通株式 | 購入 | 5,000 | $3.20 |
| 2018-07-06 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | 普通株式 | 売却 | 5,000 | $15.80 |
| 2018-06-26 | SMITH, KAREN L. | Director | 普通株式 | 購入 | 5,000 | $0.00 |
| 2018-06-26 | SMITH, KAREN L. | Director | ストックオプション | 購入 | 30,000 | $0.00 |
| 2018-06-15 | YI, KATHY | SVP & Chief Financial Officer | 普通株式 | 売却 | 5,000 | $15.67 |
| 2018-06-15 | YI, KATHY | SVP & Chief Financial Officer | 普通株式 | 購入 | 5,000 | $4.55 |
| 2018-06-15 | YI, KATHY | SVP & Chief Financial Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2018-06-11 | MENTO, STEVEN J | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2018-06-11 | MENTO, STEVEN J | Director | 普通株式 | 購入 | 2,500 | $0.00 |
| 2018-06-11 | RAMASASTRY, SAIRA | Director | 普通株式 | 購入 | 2,500 | $0.00 |
| 2018-06-11 | ZAKRZEWSKI, JOSEPH S | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2018-06-11 | ZAKRZEWSKI, JOSEPH S | Director | 普通株式 | 購入 | 2,500 | $0.00 |
| 2018-06-11 | RAMASASTRY, SAIRA | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2018-06-11 | PARKER, H STEWART | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2018-06-11 | CAREY, ROBERT | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2018-06-11 | CAREY, ROBERT | Director | 普通株式 | 購入 | 2,500 | $0.00 |
| 2018-06-11 | DILLY, STEPHEN GEORGE | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2018-06-11 | DILLY, STEPHEN GEORGE | Director | 普通株式 | 購入 | 2,500 | $0.00 |
| 2018-06-11 | JEFFS, ROGER | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2018-06-11 | JEFFS, ROGER | Director | 普通株式 | 購入 | 2,500 | $0.00 |
| 2018-06-11 | PARKER, H STEWART | Director | 普通株式 | 購入 | 2,500 | $0.00 |
| 2018-06-06 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | 普通株式 | 売却 | 5,000 | $16.67 |
| 2018-06-06 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2018-06-06 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | 普通株式 | 購入 | 5,000 | $3.20 |
| 2018-05-15 | YI, KATHY | SVP & Chief Financial Officer | 普通株式 | 売却 | 5,000 | $15.38 |
| 2018-05-15 | YI, KATHY | SVP & Chief Financial Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2018-05-15 | YI, KATHY | SVP & Chief Financial Officer | 普通株式 | 購入 | 5,000 | $4.55 |
| 2018-05-07 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | 普通株式 | 購入 | 5,000 | $3.20 |
| 2018-05-07 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2018-05-07 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | 普通株式 | 売却 | 5,000 | $16.36 |
| 2018-04-16 | YI, KATHY | SVP & Chief Financial Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2018-04-16 | YI, KATHY | SVP & Chief Financial Officer | 普通株式 | 売却 | 5,000 | $19.83 |
| 2018-04-16 | YI, KATHY | SVP & Chief Financial Officer | 普通株式 | 購入 | 5,000 | $4.55 |
| 2018-04-13 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 売却 | 8,163 | $20.00 |
| 2018-04-13 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 購入 | 8,163 | $14.07 |
| 2018-04-13 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | ストックオプション | 売却 | 8,163 | $0.00 |
| 2018-04-06 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | 普通株式 | 購入 | 5,000 | $3.20 |
| 2018-04-06 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | 普通株式 | 売却 | 5,000 | $17.41 |
| 2018-04-06 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2018-04-02 | MENTO, STEVEN J | Director | 普通株式 | 売却 | 100 | $18.90 |
| 2018-04-02 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | ストックオプション | 売却 | 1,563 | $0.00 |
| 2018-04-02 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | ストックオプション | 売却 | 715 | $0.00 |
| 2018-04-02 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 売却 | 2,278 | $18.30 |
| 2018-04-02 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 購入 | 1,563 | $3.50 |
| 2018-04-02 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 購入 | 715 | $9.41 |
| 2018-04-02 | MENTO, STEVEN J | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2018-04-02 | MENTO, STEVEN J | Director | 普通株式 | 売却 | 7,115 | $18.39 |
| 2018-04-02 | MENTO, STEVEN J | Director | 普通株式 | 購入 | 10,000 | $7.77 |
| 2018-03-15 | YI, KATHY | SVP & Chief Financial Officer | 普通株式 | 購入 | 5,000 | $4.55 |
| 2018-03-15 | YI, KATHY | SVP & Chief Financial Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2018-03-15 | YI, KATHY | SVP & Chief Financial Officer | 普通株式 | 売却 | 5,000 | $25.56 |
| 2018-03-06 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | 普通株式 | 購入 | 5,000 | $3.20 |
| 2018-03-06 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | 普通株式 | 売却 | 5,000 | $24.78 |
| 2018-03-06 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2018-03-01 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 購入 | 171 | $12.12 |
| 2018-03-01 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 購入 | 1,430 | $9.41 |
| 2018-03-01 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 購入 | 8,087 | $14.07 |
| 2018-03-01 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 購入 | 5,312 | $3.50 |
| 2018-03-01 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 売却 | 15,000 | $23.06 |
| 2018-03-01 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | ストックオプション | 売却 | 171 | $0.00 |
| 2018-03-01 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | ストックオプション | 売却 | 8,087 | $0.00 |
| 2018-03-01 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | ストックオプション | 売却 | 1,430 | $0.00 |
| 2018-03-01 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | ストックオプション | 売却 | 5,312 | $0.00 |
| 2018-03-01 | MENTO, STEVEN J | Director | 普通株式 | 購入 | 5,000 | $6.41 |
| 2018-03-01 | MENTO, STEVEN J | Director | 普通株式 | 購入 | 10,000 | $5.03 |
| 2018-03-01 | MENTO, STEVEN J | Director | 普通株式 | 売却 | 9,433 | $23.27 |
| 2018-03-01 | MENTO, STEVEN J | Director | ストックオプション | 売却 | 5,000 | $0.00 |
| 2018-03-01 | MENTO, STEVEN J | Director | 普通株式 | 売却 | 10,000 | $0.00 |
| 2018-02-28 | TURNER, HEATHER D | SVP and General Counsel | ストックオプション | 購入 | 200,000 | $0.00 |
| 2018-02-26 | RAMASASTRY, SAIRA | Director | 普通株式 | 売却 | 9,450 | $24.88 |
| 2018-02-26 | RAMASASTRY, SAIRA | Director | 普通株式 | 購入 | 9,450 | $5.03 |
| 2018-02-26 | RAMASASTRY, SAIRA | Director | ストックオプション | 売却 | 9,450 | $0.00 |
| 2018-02-06 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | 普通株式 | 売却 | 5,000 | $18.49 |
| 2018-02-06 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | 普通株式 | 購入 | 5,000 | $3.20 |
| 2018-02-06 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2018-02-01 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | ストックオプション | 売却 | 15,000 | $0.00 |
| 2018-02-01 | MENTO, STEVEN J | Director | 普通株式 | 購入 | 5,000 | $6.41 |
| 2018-02-01 | MENTO, STEVEN J | Director | 普通株式 | 購入 | 10,000 | $10.17 |
| 2018-02-01 | MENTO, STEVEN J | Director | 普通株式 | 売却 | 11,520 | $20.59 |
| 2018-02-01 | MENTO, STEVEN J | Director | ストックオプション | 売却 | 5,000 | $0.00 |
| 2018-02-01 | MENTO, STEVEN J | Director | 普通株式 | 売却 | 10,000 | $0.00 |
| 2018-02-01 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 購入 | 15,000 | $3.50 |
| 2018-02-01 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 売却 | 15,000 | $20.59 |
| 2018-01-24 | MACRAE, SANDY | Director, President, CEO and Director | 普通株式 | 購入 | 31,500 | $0.00 |
| 2018-01-24 | MACRAE, SANDY | Director, President, CEO and Director | ストックオプション | 購入 | 189,000 | $0.00 |
| 2018-01-24 | MACRAE, SANDY | Director, President and CEO | 普通株式 | 売却 | 3,974 | $11.10 |
| 2018-01-24 | YI, KATHY | SVP & Chief Financial Officer | 普通株式 | 購入 | 7,250 | $0.00 |
| 2018-01-24 | YI, KATHY | SVP & Chief Financial Officer | ストックオプション | 購入 | 43,500 | $0.00 |
| 2018-01-24 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 購入 | 8,375 | $0.00 |
| 2018-01-24 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | ストックオプション | 購入 | 50,250 | $0.00 |
| 2018-01-24 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | 普通株式 | 購入 | 6,125 | $0.00 |
| 2018-01-24 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | ストックオプション | 購入 | 36,750 | $0.00 |
| 2018-01-08 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2018-01-08 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | 普通株式 | 購入 | 5,000 | $3.20 |
| 2018-01-08 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | 普通株式 | 売却 | 5,000 | $17.11 |
| 2018-01-03 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 購入 | 8,026 | $12.12 |
| 2018-01-03 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 売却 | 8,026 | $18.05 |
| 2018-01-03 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | ストックオプション | 売却 | 8,026 | $0.00 |
| 2018-01-02 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | ストックオプション | 売却 | 782 | $0.00 |
| 2018-01-02 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | ストックオプション | 売却 | 209 | $0.00 |
| 2018-01-02 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 購入 | 782 | $9.41 |
| 2018-01-02 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 購入 | 209 | $8.87 |
| 2018-01-02 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 売却 | 6,974 | $16.35 |
| 2017-12-11 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 売却 | 1,252 | $15.85 |
| 2017-12-08 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 売却 | 2,348 | $16.90 |
| 2017-12-06 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2017-12-06 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | 普通株式 | 購入 | 5,000 | $3.20 |
| 2017-12-06 | CONNER, EDWARD R. | Sr. VP & Chief Medical Officer | 普通株式 | 売却 | 5,000 | $16.24 |
| 2017-12-04 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 購入 | 11,803 | $12.12 |
| 2017-12-04 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 売却 | 11,803 | $18.00 |
| 2017-12-04 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | ストックオプション | 売却 | 11,803 | $0.00 |
| 2017-12-01 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | ストックオプション | 売却 | 416 | $0.00 |
| 2017-12-01 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 購入 | 416 | $8.87 |
| 2017-12-01 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 売却 | 3,197 | $16.70 |
| 2017-12-01 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | ストックオプション | 売却 | 781 | $0.00 |
| 2017-12-01 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 購入 | 781 | $9.41 |
| 2017-11-30 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 売却 | 13,433 | $16.00 |
| 2017-11-30 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 購入 | 13,433 | $9.41 |
| 2017-11-30 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | ストックオプション | 売却 | 13,433 | $0.00 |
| 2017-11-17 | RAMASASTRY, SAIRA | Director | 普通株式 | 売却 | 5,000 | $14.67 |
| 2017-11-17 | RAMASASTRY, SAIRA | Director | ストックオプション | 売却 | 5,000 | $0.00 |
| 2017-11-17 | RAMASASTRY, SAIRA | Director | 普通株式 | 購入 | 5,000 | $5.03 |
| 2017-10-02 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | ストックオプション | 売却 | 3,754 | $0.00 |
| 2017-10-02 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | ストックオプション | 売却 | 5,830 | $0.00 |
| 2017-10-02 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 売却 | 3,754 | $16.00 |
| 2017-10-02 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 購入 | 5,830 | $5.41 |
| 2017-10-02 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 売却 | 5,830 | $15.00 |
| 2017-10-02 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 購入 | 5,416 | $8.87 |
| 2017-10-02 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 売却 | 5,416 | $15.00 |
| 2017-10-02 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 購入 | 3,754 | $9.41 |
| 2017-10-02 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | ストックオプション | 売却 | 5,416 | $0.00 |
| 2017-09-20 | RINGO, WILLIAM R | Director | ストックオプション | 売却 | 31,000 | $0.00 |
| 2017-09-20 | RINGO, WILLIAM R | Director | 普通株式 | 購入 | 31,000 | $6.05 |
| 2017-09-20 | RINGO, WILLIAM R | Director | 普通株式 | 売却 | 31,000 | $14.37 |
| 2017-09-01 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 購入 | 10,316 | $5.41 |
| 2017-09-01 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 売却 | 4,684 | $15.00 |
| 2017-09-01 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | ストックオプション | 売却 | 10,316 | $0.00 |
| 2017-09-01 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 売却 | 10,316 | $15.00 |
| 2017-08-14 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 購入 | 5,000 | $5.12 |
| 2017-08-14 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2017-08-14 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 売却 | 5,000 | $11.00 |
| 2017-08-11 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | ストックオプション | 売却 | 3,000 | $0.00 |
| 2017-08-11 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 購入 | 3,474 | $3.99 |
| 2017-08-11 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 購入 | 3,000 | $2.55 |
| 2017-08-11 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 売却 | 6,474 | $10.00 |
| 2017-08-11 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | ストックオプション | 売却 | 3,474 | $0.00 |
| 2017-07-14 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 売却 | 172 | $10.00 |
| 2017-07-14 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 売却 | 14,828 | $10.00 |
| 2017-07-14 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | 普通株式 | 購入 | 172 | $3.99 |
| 2017-07-14 | HERBERTS, CURT A. III | Sr.VP & Chief Business Officer | ストックオプション | 売却 | 172 | $0.00 |
| 2017-06-27 | JEFFS, ROGER | Director | ストックオプション | 購入 | 30,000 | $0.00 |
| 2017-06-27 | ZAKRZEWSKI, JOSEPH S | Director | ストックオプション | 購入 | 30,000 | $0.00 |
| 2017-06-05 | RINGO, WILLIAM R | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2017-06-05 | MENTO, STEVEN J | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2017-06-05 | DILLY, STEPHEN GEORGE | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2017-06-05 | RAMASASTRY, SAIRA | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2017-06-05 | PARKER, H STEWART | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2017-06-05 | CAREY, ROBERT | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2017-06-01 | HERBERTS, CURT A. III | Senior VP & CBO | 普通株式 | 売却 | 2,000 | $6.80 |
| 2017-05-12 | HERBERTS, CURT A. III | Senior VP & CBO | 普通株式 | 売却 | 2,000 | $8.50 |
| 2017-05-11 | HERBERTS, CURT A. III | Senior VP & CBO | 普通株式 | 売却 | 639 | $6.50 |
| 2017-02-28 | YI, KATHY | Senior VP & CFO | ストックオプション | 購入 | 200,000 | $0.00 |
| 2017-01-26 | HERBERTS, CURT A. III | Senior VP & CBO | ストックオプション | 購入 | 75,000 | $0.00 |
| 2017-01-26 | MACRAE, SANDY | President and CEO | ストックオプション | 購入 | 360,000 | $0.00 |
| 2016-12-12 | HERBERTS, CURT A. III | Senior VP & CBO | 普通株式 | 売却 | 4,852 | $3.05 |
| 2016-11-30 | CONNER, EDWARD R. | Senior VP & CMO | ストックオプション | 購入 | 200,000 | $0.00 |
| 2016-06-14 | CLEVELAND, PAUL B | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2016-06-14 | RINGO, WILLIAM R | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2016-06-14 | MENTO, STEVEN J | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2016-06-14 | DILLY, STEPHEN GEORGE | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2016-06-14 | RAMASASTRY, SAIRA | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2016-06-14 | PARKER, H STEWART | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2016-06-14 | CAREY, ROBERT | Director | ストックオプション | 購入 | 30,000 | $0.00 |
| 2016-06-13 | LANPHIER, EDWARD O II | Director | 普通株式 | 売却 | 21,741 | $6.23 |
| 2016-06-13 | LANPHIER, EDWARD O II | Director | 普通株式 | 売却 | 9,395 | $6.23 |
| 2016-06-13 | LANPHIER, EDWARD O II | Director | 普通株式 | 売却 | 15,658 | $6.23 |
| 2016-06-13 | LANPHIER, EDWARD O II | Director | 普通株式 | 売却 | 16,107 | $6.23 |
| 2016-06-07 | LANPHIER, EDWARD O II | Director | 普通株式 | 売却 | 50,000 | $0.00 |
| 2016-06-03 | MACRAE, SANDY | President and CEO | ストックオプション | 購入 | 700,000 | $0.00 |
| 2016-03-11 | LANPHIER, EDWARD O II | Director | 普通株式 | 売却 | 8,000 | $0.00 |
| 2015-12-12 | NICHOL, GEOFFREY | Executive Vice President, R&D | 普通株式 | 売却 | 4,384 | $8.68 |
| 2015-12-12 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 13,045 | $8.68 |
| 2015-12-12 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 13,778 | $3.05 |
| 2015-12-12 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 4,000 | $8.68 |
| 2015-12-12 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 6,087 | $8.68 |
| 2015-12-11 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 4,348 | $8.68 |
| 2015-12-11 | NICHOL, GEOFFREY | Executive Vice President, R&D | 普通株式 | 売却 | 4,697 | $8.68 |
| 2015-12-11 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 21,741 | $8.68 |
| 2015-12-11 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 6,522 | $8.68 |
| 2015-12-08 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 購入 | 50,000 | $0.00 |
| 2015-12-08 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 購入 | 37,500 | $0.00 |
| 2015-12-08 | NICHOL, GEOFFREY | Executive Vice President, R&D | ストックオプション | 購入 | 75,000 | $0.00 |
| 2015-12-08 | NICHOL, GEOFFREY | Executive Vice President, R&D | 普通株式 | 購入 | 37,500 | $0.00 |
| 2015-12-08 | LANPHIER, EDWARD O II | Director, President & CEO | ストックオプション | 売却 | 250,000 | $0.00 |
| 2015-12-08 | WOLFF, HENRY WARD | Exec VP & CFO | ストックオプション | 購入 | 75,000 | $0.00 |
| 2015-12-08 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 購入 | 125,000 | $0.00 |
| 2015-12-08 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 25,000 | $0.00 |
| 2015-12-07 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 13,000 | $0.00 |
| 2015-12-07 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 7,060 | $9.69 |
| 2015-12-07 | NICHOL, GEOFFREY | Executive Vice President, R&D | 普通株式 | 売却 | 6,889 | $9.69 |
| 2015-12-07 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 31,308 | $9.69 |
| 2015-12-07 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 6,087 | $9.69 |
| 2015-07-15 | LANPHIER, EDWARD O II | Director, President & CEO | ストックオプション | 売却 | 25,000 | $0.00 |
| 2015-07-15 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 25,000 | $10.43 |
| 2015-07-15 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 購入 | 25,000 | $6.82 |
| 2015-07-13 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 3,898 | $10.00 |
| 2015-07-13 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 2,000 | $10.00 |
| 2015-07-13 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 購入 | 3,898 | $3.45 |
| 2015-07-13 | WOLFF, HENRY WARD | Exec VP & CFO | ストックオプション | 購入 | 3,898 | $0.00 |
| 2015-07-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 購入 | 6,102 | $3.45 |
| 2015-07-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 6,102 | $10.00 |
| 2015-07-10 | WOLFF, HENRY WARD | Exec VP & CFO | ストックオプション | 購入 | 6,102 | $0.00 |
| 2015-06-22 | PARKER, H STEWART | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2015-06-22 | RINGO, WILLIAM R | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2015-06-22 | DILLY, STEPHEN GEORGE | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2015-06-22 | CLEVELAND, PAUL B | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2015-06-22 | LARSON, JOHN WILLIAM | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2015-06-22 | MENTO, STEVEN J | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2015-06-22 | RAMASASTRY, SAIRA | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2015-06-15 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 購入 | 25,000 | $6.82 |
| 2015-06-15 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 25,000 | $11.08 |
| 2015-06-15 | LANPHIER, EDWARD O II | Director, President & CEO | ストックオプション | 購入 | 25,000 | $0.00 |
| 2015-06-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 購入 | 10,000 | $3.45 |
| 2015-06-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 10,000 | $12.21 |
| 2015-06-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 2,000 | $12.21 |
| 2015-06-10 | WOLFF, HENRY WARD | Exec VP & CFO | ストックオプション | 購入 | 10,000 | $0.00 |
| 2015-06-05 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 購入 | 15,000 | $0.00 |
| 2015-06-05 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 15,000 | $12.29 |
| 2015-06-05 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 15,000 | $3.45 |
| 2015-06-03 | RINGO, WILLIAM R | Director | ストックオプション | 売却 | 2,200 | $0.00 |
| 2015-06-03 | RINGO, WILLIAM R | Director | 普通株式 | 売却 | 2,200 | $12.44 |
| 2015-06-03 | RINGO, WILLIAM R | Director | 普通株式 | 購入 | 2,200 | $6.05 |
| 2015-06-01 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 7,000 | $5.70 |
| 2015-06-01 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 購入 | 3,000 | $0.00 |
| 2015-06-01 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 購入 | 5,000 | $0.00 |
| 2015-06-01 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 購入 | 7,000 | $0.00 |
| 2015-06-01 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 3,000 | $3.45 |
| 2015-06-01 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 売却 | 15,000 | $12.39 |
| 2015-06-01 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 5,000 | $5.35 |
| 2015-05-15 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 購入 | 25,000 | $6.82 |
| 2015-05-15 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 25,000 | $11.51 |
| 2015-05-15 | LANPHIER, EDWARD O II | Director, President & CEO | ストックオプション | 売却 | 25,000 | $0.00 |
| 2015-05-11 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 購入 | 10,000 | $3.45 |
| 2015-05-11 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 10,000 | $13.25 |
| 2015-05-11 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 2,000 | $13.25 |
| 2015-05-11 | WOLFF, HENRY WARD | Exec VP & CFO | ストックオプション | 購入 | 10,000 | $0.00 |
| 2015-05-05 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 15,000 | $3.45 |
| 2015-05-05 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 15,000 | $12.29 |
| 2015-05-05 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 購入 | 15,000 | $0.00 |
| 2015-05-04 | RINGO, WILLIAM R | Director | 普通株式 | 売却 | 3,000 | $12.98 |
| 2015-05-04 | RINGO, WILLIAM R | Director | 普通株式 | 購入 | 1,200 | $6.41 |
| 2015-05-04 | RINGO, WILLIAM R | Director | 普通株式 | 購入 | 1,800 | $6.05 |
| 2015-05-04 | RINGO, WILLIAM R | Director | ストックオプション | 購入 | 1,200 | $0.00 |
| 2015-05-04 | RINGO, WILLIAM R | Director | ストックオプション | 購入 | 1,800 | $0.00 |
| 2015-05-01 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 3,000 | $3.45 |
| 2015-05-01 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 5,000 | $5.35 |
| 2015-05-01 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 7,000 | $5.70 |
| 2015-05-01 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 売却 | 15,000 | $12.62 |
| 2015-05-01 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 購入 | 3,000 | $0.00 |
| 2015-05-01 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 購入 | 5,000 | $0.00 |
| 2015-05-01 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 購入 | 7,000 | $0.00 |
| 2015-04-15 | LANPHIER, EDWARD O II | Director, President & CEO | ストックオプション | 売却 | 25,000 | $0.00 |
| 2015-04-15 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 25,000 | $15.33 |
| 2015-04-15 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 購入 | 25,000 | $6.82 |
| 2015-04-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 971 | $15.43 |
| 2015-04-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 購入 | 10,000 | $3.45 |
| 2015-04-10 | WOLFF, HENRY WARD | Exec VP & CFO | ストックオプション | 購入 | 10,000 | $0.00 |
| 2015-04-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 1,029 | $15.37 |
| 2015-04-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 10,000 | $15.30 |
| 2015-04-06 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 15,000 | $14.94 |
| 2015-04-06 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 15,000 | $3.45 |
| 2015-04-06 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 購入 | 15,000 | $0.00 |
| 2015-04-06 | RINGO, WILLIAM R | Director | 普通株式 | 購入 | 2,200 | $6.41 |
| 2015-04-06 | RINGO, WILLIAM R | Director | 普通株式 | 売却 | 2,200 | $14.95 |
| 2015-04-06 | RINGO, WILLIAM R | Director | ストックオプション | 売却 | 2,200 | $0.00 |
| 2015-04-01 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 5,000 | $5.35 |
| 2015-04-01 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 7,000 | $5.70 |
| 2015-04-01 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 売却 | 3,000 | $0.00 |
| 2015-04-01 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 売却 | 5,000 | $0.00 |
| 2015-04-01 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 売却 | 15,000 | $15.15 |
| 2015-04-01 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 売却 | 7,000 | $0.00 |
| 2015-04-01 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 3,000 | $3.45 |
| 2015-03-19 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 10,000 | $18.00 |
| 2015-03-19 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 購入 | 10,000 | $14.27 |
| 2015-03-19 | WOLFF, HENRY WARD | Exec VP & CFO | ストックオプション | 購入 | 10,000 | $0.00 |
| 2015-03-17 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 3,500 | $0.00 |
| 2015-03-16 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 購入 | 25,000 | $6.82 |
| 2015-03-16 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 25,000 | $17.29 |
| 2015-03-16 | LANPHIER, EDWARD O II | Director, President & CEO | ストックオプション | 売却 | 25,000 | $0.00 |
| 2015-03-10 | WOLFF, HENRY WARD | Exec VP & CFO | ストックオプション | 購入 | 10,000 | $0.00 |
| 2015-03-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 10,000 | $16.68 |
| 2015-03-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 購入 | 10,000 | $3.45 |
| 2015-03-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 2,000 | $16.68 |
| 2015-03-05 | MENTO, STEVEN J | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2015-03-05 | MENTO, STEVEN J | Director | 普通株式 | 売却 | 6,501 | $18.30 |
| 2015-03-05 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 15,000 | $3.45 |
| 2015-03-05 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 15,000 | $18.29 |
| 2015-03-05 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 15,000 | $0.00 |
| 2015-03-05 | MENTO, STEVEN J | Director | 普通株式 | 購入 | 10,000 | $4.54 |
| 2015-03-04 | WOLFF, HENRY WARD | Exec VP & CFO | ストックオプション | 購入 | 10,000 | $0.00 |
| 2015-03-04 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 10,000 | $18.00 |
| 2015-03-04 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 購入 | 10,000 | $14.27 |
| 2015-03-03 | RINGO, WILLIAM R | Director | 普通株式 | 売却 | 2,200 | $17.21 |
| 2015-03-03 | RINGO, WILLIAM R | Director | ストックオプション | 売却 | 2,200 | $0.00 |
| 2015-03-03 | RINGO, WILLIAM R | Director | 普通株式 | 購入 | 2,200 | $6.41 |
| 2015-03-02 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 3,000 | $3.45 |
| 2015-03-02 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 3,000 | $5.70 |
| 2015-03-02 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 5,000 | $5.35 |
| 2015-03-02 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 売却 | 15,000 | $17.26 |
| 2015-03-02 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 売却 | 5,000 | $0.00 |
| 2015-03-02 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 売却 | 3,000 | $0.00 |
| 2015-03-02 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 売却 | 4,000 | $0.00 |
| 2015-03-02 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 4,000 | $13.98 |
| 2015-02-17 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 購入 | 25,000 | $6.82 |
| 2015-02-17 | LANPHIER, EDWARD O II | Director, President & CEO | ストックオプション | 売却 | 25,000 | $0.00 |
| 2015-02-17 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 25,000 | $15.69 |
| 2015-02-12 | RAMASASTRY, SAIRA | Director | 普通株式 | 購入 | 10,000 | $5.03 |
| 2015-02-12 | RAMASASTRY, SAIRA | Director | 普通株式 | 売却 | 10,000 | $15.00 |
| 2015-02-12 | RAMASASTRY, SAIRA | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2015-02-10 | WOLFF, HENRY WARD | Exec VP & CFO | ストックオプション | 購入 | 10,000 | $0.00 |
| 2015-02-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 1,029 | $12.65 |
| 2015-02-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 購入 | 10,000 | $3.45 |
| 2015-02-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 10,000 | $12.65 |
| 2015-02-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 971 | $12.63 |
| 2015-02-05 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 11,798 | $0.00 |
| 2015-02-05 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 3,202 | $0.00 |
| 2015-02-05 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 3,202 | $3.45 |
| 2015-02-05 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 11,798 | $6.82 |
| 2015-02-05 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 15,000 | $12.93 |
| 2015-02-03 | RINGO, WILLIAM R | Director | ストックオプション | 売却 | 2,200 | $0.00 |
| 2015-02-03 | RINGO, WILLIAM R | Director | 普通株式 | 売却 | 2,200 | $12.70 |
| 2015-02-03 | RINGO, WILLIAM R | Director | 普通株式 | 購入 | 2,200 | $6.41 |
| 2015-02-02 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 売却 | 5,000 | $0.00 |
| 2015-02-02 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 売却 | 3,000 | $0.00 |
| 2015-02-02 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 売却 | 15,000 | $12.86 |
| 2015-02-02 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 7,000 | $5.70 |
| 2015-02-02 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 5,000 | $5.35 |
| 2015-02-02 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 3,000 | $3.45 |
| 2015-02-02 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 売却 | 7,000 | $0.00 |
| 2015-01-16 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 10,000 | $14.29 |
| 2015-01-16 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 10,000 | $6.82 |
| 2015-01-16 | LANPHIER, EDWARD O II | Director, President & CEO | ストックオプション | 売却 | 10,000 | $0.00 |
| 2015-01-15 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 購入 | 15,000 | $6.82 |
| 2015-01-15 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 13,400 | $14.09 |
| 2015-01-15 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 1,600 | $14.97 |
| 2015-01-15 | LANPHIER, EDWARD O II | Director, President & CEO | ストックオプション | 売却 | 15,000 | $0.00 |
| 2015-01-12 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 10,000 | $15.87 |
| 2015-01-12 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 購入 | 10,000 | $3.45 |
| 2015-01-12 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 2,000 | $15.87 |
| 2015-01-12 | WOLFF, HENRY WARD | Exec VP & CFO | ストックオプション | 購入 | 10,000 | $0.00 |
| 2015-01-05 | LARSON, JOHN WILLIAM | Director | ストックオプション | 売却 | 5,000 | $0.00 |
| 2015-01-05 | LARSON, JOHN WILLIAM | Director | 普通株式 | 購入 | 5,000 | $5.03 |
| 2015-01-05 | RINGO, WILLIAM R | Director | ストックオプション | 売却 | 2,200 | $0.00 |
| 2015-01-05 | LARSON, JOHN WILLIAM | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2015-01-05 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 1,500 | $0.00 |
| 2015-01-05 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 600 | $15.66 |
| 2015-01-05 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 15,000 | $15.10 |
| 2015-01-05 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 14,400 | $15.17 |
| 2015-01-05 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 15,000 | $6.82 |
| 2015-01-05 | LARSON, JOHN WILLIAM | Director | 普通株式 | 購入 | 10,000 | $7.77 |
| 2015-01-05 | RINGO, WILLIAM R | Director | 普通株式 | 購入 | 2,200 | $6.41 |
| 2015-01-05 | RINGO, WILLIAM R | Director | 普通株式 | 売却 | 2,200 | $15.20 |
| 2015-01-02 | GREGORY, PHILIP D | SVP, Research & CSO | 普通株式 | 購入 | 3,000 | $3.45 |
| 2015-01-02 | GREGORY, PHILIP D | SVP, Research & CSO | ストックオプション | 売却 | 5,000 | $0.00 |
| 2015-01-02 | GREGORY, PHILIP D | SVP, Research & CSO | 普通株式 | 購入 | 4,000 | $13.98 |
| 2015-01-02 | GREGORY, PHILIP D | SVP, Research & CSO | 普通株式 | 売却 | 15,000 | $15.78 |
| 2015-01-02 | GREGORY, PHILIP D | SVP, Research & CSO | ストックオプション | 売却 | 3,000 | $0.00 |
| 2015-01-02 | GREGORY, PHILIP D | SVP, Research & CSO | ストックオプション | 売却 | 4,000 | $0.00 |
| 2015-01-02 | GREGORY, PHILIP D | SVP, Research & CSO | 普通株式 | 購入 | 5,000 | $5.35 |
| 2015-01-02 | GREGORY, PHILIP D | SVP, Research & CSO | 普通株式 | 購入 | 3,000 | $5.70 |
| 2014-12-15 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 96,533 | $14.74 |
| 2014-12-15 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 27,480 | $14.74 |
| 2014-12-15 | NICHOL, GEOFFREY | Executive Vice President, R&D | 普通株式 | 売却 | 41,743 | $14.74 |
| 2014-12-15 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 購入 | 25,000 | $4.11 |
| 2014-12-15 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 9,000 | $16.47 |
| 2014-12-15 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 16,000 | $14.79 |
| 2014-12-15 | LANPHIER, EDWARD O II | Director, President & CEO | ストックオプション | 売却 | 25,000 | $0.00 |
| 2014-12-15 | LARSON, JOHN WILLIAM | Director | 普通株式 | 購入 | 10,000 | $6.41 |
| 2014-12-15 | LARSON, JOHN WILLIAM | Director | 普通株式 | 購入 | 5,000 | $5.03 |
| 2014-12-15 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 10,000 | $16.28 |
| 2014-12-15 | LARSON, JOHN WILLIAM | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2014-12-15 | LARSON, JOHN WILLIAM | Director | ストックオプション | 売却 | 5,000 | $0.00 |
| 2014-12-15 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 売却 | 30,437 | $14.74 |
| 2014-12-15 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 40,004 | $14.74 |
| 2014-12-11 | LANPHIER, EDWARD O II | Director, President & CEO | ストックオプション | 購入 | 250,000 | $0.00 |
| 2014-12-11 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 購入 | 125,000 | $0.00 |
| 2014-12-11 | NICHOL, GEOFFREY | Executive Vice President, R&D | ストックオプション | 購入 | 75,000 | $0.00 |
| 2014-12-11 | NICHOL, GEOFFREY | Executive Vice President, R&D | 普通株式 | 購入 | 37,500 | $0.00 |
| 2014-12-11 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 25,000 | $0.00 |
| 2014-12-11 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 購入 | 37,500 | $0.00 |
| 2014-12-11 | WOLFF, HENRY WARD | Exec VP & CFO | ストックオプション | 購入 | 75,000 | $0.00 |
| 2014-12-11 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 購入 | 37,500 | $0.00 |
| 2014-12-11 | GREGORY, PHILIP D | Vice President, Research & CSO | ストックオプション | 購入 | 75,000 | $0.00 |
| 2014-12-11 | MENTO, STEVEN J | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2014-12-11 | MENTO, STEVEN J | Director | 普通株式 | 売却 | 6,354 | $15.00 |
| 2014-12-11 | MENTO, STEVEN J | Director | 普通株式 | 購入 | 10,000 | $4.10 |
| 2014-12-11 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 購入 | 50,000 | $0.00 |
| 2014-12-09 | LARSON, JOHN WILLIAM | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2014-12-09 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 10,000 | $12.00 |
| 2014-12-09 | LARSON, JOHN WILLIAM | Director | 普通株式 | 購入 | 10,000 | $4.54 |
| 2014-12-05 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 15,000 | $11.21 |
| 2014-12-05 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 15,000 | $0.00 |
| 2014-12-05 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 15,000 | $6.82 |
| 2014-12-01 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 売却 | 3,000 | $0.00 |
| 2014-12-01 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 売却 | 15,000 | $11.68 |
| 2014-12-01 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 7,000 | $5.70 |
| 2014-12-01 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 3,000 | $3.45 |
| 2014-12-01 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 5,000 | $5.35 |
| 2014-12-01 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 売却 | 7,000 | $0.00 |
| 2014-12-01 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 売却 | 5,000 | $0.00 |
| 2014-11-17 | LANPHIER, EDWARD O II | Director, President & CEO | ストックオプション | 売却 | 25,000 | $0.00 |
| 2014-11-17 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 購入 | 25,000 | $4.11 |
| 2014-11-17 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 25,000 | $11.23 |
| 2014-11-12 | LARSON, JOHN WILLIAM | Director | 普通株式 | 購入 | 10,000 | $4.10 |
| 2014-11-12 | LARSON, JOHN WILLIAM | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2014-11-12 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 10,000 | $12.00 |
| 2014-11-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 2,000 | $11.37 |
| 2014-11-05 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 15,000 | $11.35 |
| 2014-11-05 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 8,202 | $6.82 |
| 2014-11-05 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 6,798 | $0.00 |
| 2014-11-05 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 6,798 | $4.11 |
| 2014-11-05 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 8,202 | $0.00 |
| 2014-11-03 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 売却 | 15,000 | $11.91 |
| 2014-11-03 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 2,000 | $6.82 |
| 2014-11-03 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 3,000 | $3.45 |
| 2014-11-03 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 5,000 | $5.35 |
| 2014-11-03 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 5,000 | $5.70 |
| 2014-11-03 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 売却 | 2,000 | $0.00 |
| 2014-11-03 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 売却 | 3,000 | $0.00 |
| 2014-11-03 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 売却 | 5,000 | $0.00 |
| 2014-10-28 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 10,000 | $12.02 |
| 2014-10-28 | LARSON, JOHN WILLIAM | Director | 普通株式 | 購入 | 10,000 | $7.28 |
| 2014-10-28 | LARSON, JOHN WILLIAM | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2014-10-15 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 25,000 | $10.49 |
| 2014-10-15 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 購入 | 25,000 | $4.11 |
| 2014-10-15 | LANPHIER, EDWARD O II | Director, President & CEO | ストックオプション | 売却 | 25,000 | $0.00 |
| 2014-10-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 2,000 | $10.10 |
| 2014-10-06 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 15,000 | $4.11 |
| 2014-10-06 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 購入 | 15,000 | $0.00 |
| 2014-10-06 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 15,000 | $10.72 |
| 2014-10-01 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 3,000 | $3.45 |
| 2014-10-01 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 売却 | 15,000 | $10.80 |
| 2014-10-01 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 7,000 | $6.82 |
| 2014-10-01 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 5,000 | $5.35 |
| 2014-10-01 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 売却 | 7,000 | $0.00 |
| 2014-10-01 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 売却 | 3,000 | $0.00 |
| 2014-10-01 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 売却 | 5,000 | $0.00 |
| 2014-09-15 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 購入 | 25,000 | $4.11 |
| 2014-09-15 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 25,000 | $12.14 |
| 2014-09-15 | LANPHIER, EDWARD O II | Director, President & CEO | ストックオプション | 売却 | 25,000 | $0.00 |
| 2014-09-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 2,000 | $12.31 |
| 2014-09-05 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 15,000 | $0.00 |
| 2014-09-05 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 15,000 | $4.11 |
| 2014-09-05 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 15,000 | $12.20 |
| 2014-09-04 | LARSON, JOHN WILLIAM | Director | 普通株式 | 購入 | 10,000 | $7.73 |
| 2014-09-04 | LARSON, JOHN WILLIAM | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2014-09-04 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 10,000 | $12.81 |
| 2014-09-02 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 1,000 | $0.00 |
| 2014-09-02 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 売却 | 15,000 | $13.45 |
| 2014-09-02 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 売却 | 7,000 | $0.00 |
| 2014-09-02 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 売却 | 3,000 | $0.00 |
| 2014-09-02 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 売却 | 5,000 | $0.00 |
| 2014-09-02 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 5,000 | $5.35 |
| 2014-09-02 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 7,000 | $6.82 |
| 2014-09-02 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 3,000 | $3.45 |
| 2014-08-15 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 購入 | 25,000 | $4.11 |
| 2014-08-15 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 25,000 | $13.95 |
| 2014-08-15 | LANPHIER, EDWARD O II | Director, President & CEO | ストックオプション | 売却 | 25,000 | $0.00 |
| 2014-08-11 | WOLFF, HENRY WARD | Exec VP & CFO | ストックオプション | 売却 | 8,000 | $0.00 |
| 2014-08-11 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 購入 | 8,000 | $7.28 |
| 2014-08-11 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 8,000 | $14.17 |
| 2014-08-11 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 2,000 | $14.14 |
| 2014-08-08 | RAMASASTRY, SAIRA | Director | 普通株式 | 売却 | 10,000 | $14.00 |
| 2014-08-08 | RAMASASTRY, SAIRA | Director | 普通株式 | 購入 | 10,000 | $5.03 |
| 2014-08-08 | RAMASASTRY, SAIRA | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2014-08-05 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 1,798 | $12.98 |
| 2014-08-05 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 13,202 | $4.11 |
| 2014-08-05 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 13,202 | $12.99 |
| 2014-08-05 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 13,202 | $0.00 |
| 2014-08-04 | LARSON, JOHN WILLIAM | Director | 普通株式 | 購入 | 10,000 | $4.00 |
| 2014-08-04 | LARSON, JOHN WILLIAM | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2014-08-04 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 10,000 | $12.56 |
| 2014-08-01 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 売却 | 7,000 | $0.00 |
| 2014-08-01 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 27,770 | $12.82 |
| 2014-08-01 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 3,000 | $3.45 |
| 2014-08-01 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 売却 | 5,000 | $0.00 |
| 2014-08-01 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 売却 | 3,000 | $0.00 |
| 2014-08-01 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 7,000 | $6.82 |
| 2014-08-01 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 5,000 | $5.35 |
| 2014-08-01 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 売却 | 15,000 | $12.54 |
| 2014-07-30 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 20,592 | $12.35 |
| 2014-07-30 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 57,890 | $12.36 |
| 2014-07-30 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 31,108 | $12.59 |
| 2014-07-29 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 1,407 | $12.41 |
| 2014-07-28 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 35,271 | $12.11 |
| 2014-07-28 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 24,810 | $12.10 |
| 2014-07-25 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 47,429 | $12.31 |
| 2014-07-24 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 124,050 | $12.28 |
| 2014-07-18 | LANPHIER, EDWARD O II | Director, President & CEO | ストックオプション | 売却 | 25,000 | $0.00 |
| 2014-07-18 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 25,000 | $12.16 |
| 2014-07-18 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 購入 | 25,000 | $4.11 |
| 2014-07-17 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 37,215 | $12.26 |
| 2014-07-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 2,000 | $13.19 |
| 2014-07-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 購入 | 11,000 | $7.73 |
| 2014-07-10 | WOLFF, HENRY WARD | Exec VP & CFO | ストックオプション | 売却 | 11,000 | $0.00 |
| 2014-07-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 購入 | 2,000 | $7.28 |
| 2014-07-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 13,000 | $13.27 |
| 2014-07-10 | WOLFF, HENRY WARD | Exec VP & CFO | ストックオプション | 売却 | 2,000 | $0.00 |
| 2014-07-01 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 33,080 | $15.96 |
| 2014-07-01 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 49,620 | $16.05 |
| 2014-07-01 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 売却 | 5,000 | $0.00 |
| 2014-07-01 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 7,000 | $6.82 |
| 2014-07-01 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 3,000 | $3.45 |
| 2014-07-01 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 5,000 | $5.35 |
| 2014-07-01 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 売却 | 15,000 | $15.66 |
| 2014-07-01 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 売却 | 7,000 | $0.00 |
| 2014-07-01 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 売却 | 3,000 | $0.00 |
| 2014-06-23 | RAMASASTRY, SAIRA | Director | 普通株式 | 購入 | 5,550 | $5.03 |
| 2014-06-23 | RAMASASTRY, SAIRA | Director | ストックオプション | 売却 | 5,550 | $0.00 |
| 2014-06-23 | RAMASASTRY, SAIRA | Director | 普通株式 | 売却 | 5,550 | $15.53 |
| 2014-06-17 | PARKER, H STEWART | Director | ストックオプション | 売却 | 50,000 | $0.00 |
| 2014-06-16 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 107,796 | $16.60 |
| 2014-06-16 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 137,171 | $16.52 |
| 2014-06-16 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 3,695 | $16.52 |
| 2014-06-16 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 1,838 | $16.35 |
| 2014-06-16 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 25,000 | $16.41 |
| 2014-06-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 13,000 | $15.62 |
| 2014-06-10 | WOLFF, HENRY WARD | Exec VP & CFO | ストックオプション | 売却 | 13,000 | $0.00 |
| 2014-06-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 2,000 | $15.63 |
| 2014-06-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 購入 | 13,000 | $7.73 |
| 2014-06-09 | MENTO, STEVEN J | Director | 普通株式 | 購入 | 5,834 | $7.28 |
| 2014-06-09 | MENTO, STEVEN J | Director | 普通株式 | 売却 | 4,328 | $15.00 |
| 2014-06-09 | MENTO, STEVEN J | Director | ストックオプション | 購入 | 5,834 | $0.00 |
| 2014-06-09 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 60,955 | $15.50 |
| 2014-06-09 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 22,545 | $15.50 |
| 2014-06-06 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 41,749 | $14.13 |
| 2014-06-06 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 9,852 | $14.07 |
| 2014-06-06 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 83,500 | $14.40 |
| 2014-06-05 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 586 | $13.11 |
| 2014-06-05 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 18,377 | $13.98 |
| 2014-06-05 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 66,253 | $14.13 |
| 2014-06-05 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 48,849 | $14.14 |
| 2014-06-05 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 918,499 | $13.00 |
| 2014-06-05 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 32,899 | $14.13 |
| 2014-06-04 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 20,826 | $13.11 |
| 2014-06-04 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 29,155 | $13.11 |
| 2014-06-04 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 20,659 | $13.08 |
| 2014-06-03 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 76,833 | $12.86 |
| 2014-06-02 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 3,000 | $3.45 |
| 2014-06-02 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 売却 | 5,000 | $0.00 |
| 2014-06-02 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 売却 | 3,000 | $0.00 |
| 2014-06-02 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 売却 | 7,000 | $0.00 |
| 2014-06-02 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 売却 | 15,000 | $12.85 |
| 2014-06-02 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 7,000 | $6.82 |
| 2014-06-02 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 5,000 | $5.35 |
| 2014-05-30 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 41,651 | $13.38 |
| 2014-05-30 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 24,233 | $13.45 |
| 2014-05-29 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 146,285 | $13.53 |
| 2014-05-29 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 9,390 | $13.51 |
| 2014-05-28 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 24,302 | $13.47 |
| 2014-05-28 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 124,387 | $13.42 |
| 2014-05-27 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 13,000 | $0.00 |
| 2014-05-27 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 2,000 | $0.00 |
| 2014-05-27 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 108,863 | $13.56 |
| 2014-05-27 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 154,574 | $13.55 |
| 2014-05-27 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 2,000 | $5.19 |
| 2014-05-27 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 2,000 | $13.57 |
| 2014-05-27 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 13,000 | $3.45 |
| 2014-05-27 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 13,000 | $13.57 |
| 2014-05-23 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 51,597 | $13.27 |
| 2014-05-22 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 40,818 | $13.58 |
| 2014-05-22 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 15,578 | $13.51 |
| 2014-05-15 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 25,000 | $13.14 |
| 2014-05-13 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 56,060 | $13.12 |
| 2014-05-12 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 10,270 | $13.06 |
| 2014-05-12 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 購入 | 13,000 | $7.73 |
| 2014-05-12 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 13,000 | $12.85 |
| 2014-05-12 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 2,000 | $12.85 |
| 2014-05-12 | WOLFF, HENRY WARD | Exec VP & CFO | ストックオプション | 売却 | 13,000 | $0.00 |
| 2014-05-12 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 19,389 | $13.01 |
| 2014-05-08 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 20,825 | $12.39 |
| 2014-05-08 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 62,475 | $12.40 |
| 2014-05-07 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 40,566 | $11.74 |
| 2014-05-07 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 6,998 | $11.71 |
| 2014-05-07 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 35,736 | $12.09 |
| 2014-05-01 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 7,000 | $6.82 |
| 2014-05-01 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 売却 | 3,000 | $0.00 |
| 2014-05-01 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 3,000 | $3.45 |
| 2014-05-01 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 売却 | 5,000 | $0.00 |
| 2014-05-01 | GREGORY, PHILIP D | SVP of Research & CSO | ストックオプション | 売却 | 7,000 | $0.00 |
| 2014-05-01 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 売却 | 15,000 | $13.68 |
| 2014-05-01 | GREGORY, PHILIP D | SVP of Research & CSO | 普通株式 | 購入 | 5,000 | $5.35 |
| 2014-04-30 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 73,289 | $13.57 |
| 2014-04-30 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 51,211 | $13.29 |
| 2014-04-28 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 13,000 | $3.45 |
| 2014-04-28 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 74,844 | $13.29 |
| 2014-04-28 | LARSON, JOHN WILLIAM | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2014-04-28 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 10,000 | $13.48 |
| 2014-04-28 | LARSON, JOHN WILLIAM | Director | 普通株式 | 購入 | 10,000 | $5.66 |
| 2014-04-28 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 2,000 | $0.00 |
| 2014-04-28 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 13,000 | $0.00 |
| 2014-04-28 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 2,000 | $13.63 |
| 2014-04-28 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 2,000 | $5.19 |
| 2014-04-28 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 13,000 | $13.64 |
| 2014-04-25 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 166,000 | $13.63 |
| 2014-04-22 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 39,591 | $14.70 |
| 2014-04-22 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 43,409 | $14.86 |
| 2014-04-22 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 166,000 | $14.86 |
| 2014-04-22 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 62,250 | $14.88 |
| 2014-04-22 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 41,500 | $15.02 |
| 2014-04-21 | DILLY, STEPHEN GEORGE | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2014-04-21 | RINGO, WILLIAM R | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2014-04-21 | MENTO, STEVEN J | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2014-04-21 | RAMASASTRY, SAIRA | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2014-04-21 | LARSON, JOHN WILLIAM | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2014-04-21 | CLEVELAND, PAUL B | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2014-04-17 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 41,500 | $14.02 |
| 2014-04-16 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 21,829 | $14.09 |
| 2014-04-15 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 1,079 | $13.10 |
| 2014-04-15 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 25,000 | $14.20 |
| 2014-04-15 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 20,750 | $13.16 |
| 2014-04-14 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 3,055 | $14.78 |
| 2014-04-11 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 83,000 | $14.48 |
| 2014-04-11 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 33,992 | $14.49 |
| 2014-04-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 2,000 | $15.74 |
| 2014-04-10 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 3,403 | $15.67 |
| 2014-04-10 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 83,000 | $14.91 |
| 2014-04-10 | WOLFF, HENRY WARD | Exec VP & CFO | ストックオプション | 売却 | 13,000 | $0.00 |
| 2014-04-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 13,000 | $15.72 |
| 2014-04-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 購入 | 13,000 | $7.73 |
| 2014-04-09 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 69,856 | $16.27 |
| 2014-04-08 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 121,876 | $15.49 |
| 2014-04-07 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 33,667 | $15.42 |
| 2014-04-04 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 179,031 | $15.38 |
| 2014-04-03 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 195,126 | $16.61 |
| 2014-04-01 | GREGORY, PHILIP D | Sr. VP Res. & CSO | ストックオプション | 売却 | 4,000 | $0.00 |
| 2014-04-01 | GREGORY, PHILIP D | Sr. VP Res. & CSO | ストックオプション | 売却 | 3,000 | $0.00 |
| 2014-04-01 | GREGORY, PHILIP D | Sr. VP Res. & CSO | 普通株式 | 売却 | 15,000 | $17.80 |
| 2014-04-01 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 24,900 | $17.89 |
| 2014-04-01 | GREGORY, PHILIP D | Sr. VP Res. & CSO | 普通株式 | 購入 | 5,000 | $5.35 |
| 2014-04-01 | GREGORY, PHILIP D | Sr. VP Res. & CSO | 普通株式 | 購入 | 3,000 | $3.45 |
| 2014-04-01 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 75,100 | $18.14 |
| 2014-04-01 | GREGORY, PHILIP D | Sr. VP Res. & CSO | 普通株式 | 購入 | 4,000 | $13.98 |
| 2014-04-01 | GREGORY, PHILIP D | Sr. VP Res. & CSO | 普通株式 | 購入 | 3,000 | $6.82 |
| 2014-04-01 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 50,000 | $17.95 |
| 2014-04-01 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 48,500 | $17.88 |
| 2014-04-01 | GREGORY, PHILIP D | Sr. VP Res. & CSO | ストックオプション | 売却 | 5,000 | $0.00 |
| 2014-04-01 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 51,500 | $18.08 |
| 2014-03-28 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 21,840 | $17.07 |
| 2014-03-28 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 62,160 | $17.11 |
| 2014-03-27 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 4,200 | $17.35 |
| 2014-03-27 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 251,987 | $17.66 |
| 2014-03-26 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 19,320 | $17.88 |
| 2014-03-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 12,800 | $18.64 |
| 2014-03-26 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 190,693 | $18.16 |
| 2014-03-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 13,000 | $3.45 |
| 2014-03-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 2,000 | $18.64 |
| 2014-03-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 2,000 | $5.19 |
| 2014-03-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 200 | $19.10 |
| 2014-03-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 2,000 | $0.00 |
| 2014-03-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 13,000 | $0.00 |
| 2014-03-25 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 21,000 | $19.33 |
| 2014-03-25 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 42,000 | $19.44 |
| 2014-03-25 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 21,000 | $19.46 |
| 2014-03-21 | GREGORY, PHILIP D | See Remarks | 普通株式 | 購入 | 1,791 | $4.11 |
| 2014-03-21 | GREGORY, PHILIP D | See Remarks | ストックオプション | 売却 | 1,209 | $0.00 |
| 2014-03-21 | GREGORY, PHILIP D | See Remarks | ストックオプション | 売却 | 4,000 | $0.00 |
| 2014-03-21 | GREGORY, PHILIP D | See Remarks | ストックオプション | 売却 | 3,000 | $0.00 |
| 2014-03-21 | GREGORY, PHILIP D | See Remarks | ストックオプション | 売却 | 1,791 | $0.00 |
| 2014-03-21 | GREGORY, PHILIP D | See Remarks | 普通株式 | 売却 | 15,000 | $22.38 |
| 2014-03-21 | GREGORY, PHILIP D | See Remarks | ストックオプション | 売却 | 5,000 | $0.00 |
| 2014-03-21 | GREGORY, PHILIP D | See Remarks | 普通株式 | 購入 | 5,000 | $5.35 |
| 2014-03-21 | GREGORY, PHILIP D | See Remarks | 普通株式 | 購入 | 1,209 | $3.45 |
| 2014-03-21 | GREGORY, PHILIP D | See Remarks | 普通株式 | 購入 | 4,000 | $13.98 |
| 2014-03-21 | GREGORY, PHILIP D | See Remarks | 普通株式 | 購入 | 3,000 | $6.82 |
| 2014-03-21 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 101,808 | $21.22 |
| 2014-03-19 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 17,808 | $24.28 |
| 2014-03-18 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 34,440 | $23.74 |
| 2014-03-18 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 49,560 | $23.75 |
| 2014-03-17 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 52,161 | $23.02 |
| 2014-03-17 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 購入 | 50,000 | $5.19 |
| 2014-03-17 | RAMASASTRY, SAIRA | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2014-03-17 | RAMASASTRY, SAIRA | Director | 普通株式 | 売却 | 10,000 | $23.26 |
| 2014-03-17 | LANPHIER, EDWARD O II | Director, President & CEO | ストックオプション | 売却 | 50,000 | $0.00 |
| 2014-03-17 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 50,000 | $23.22 |
| 2014-03-17 | RAMASASTRY, SAIRA | Director | 普通株式 | 購入 | 10,000 | $5.03 |
| 2014-03-14 | MENTO, STEVEN J | Director | 普通株式 | 売却 | 6,103 | $22.77 |
| 2014-03-14 | MENTO, STEVEN J | Director | 普通株式 | 購入 | 9,722 | $3.87 |
| 2014-03-14 | MENTO, STEVEN J | Director | ストックオプション | 購入 | 9,722 | $0.00 |
| 2014-03-13 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 71,319 | $22.76 |
| 2014-03-12 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 123,480 | $23.40 |
| 2014-03-11 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 2,500 | $0.00 |
| 2014-03-10 | WOLFF, HENRY WARD | Exec VP & CFO | ストックオプション | 購入 | 10,000 | $0.00 |
| 2014-03-10 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 12,522 | $22.30 |
| 2014-03-10 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 4,000 | $0.00 |
| 2014-03-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 10,000 | $22.31 |
| 2014-03-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 購入 | 10,000 | $3.45 |
| 2014-03-07 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 258,377 | $22.25 |
| 2014-03-06 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 42,000 | $22.56 |
| 2014-03-06 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 42,001 | $22.45 |
| 2014-03-06 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 21,001 | $24.10 |
| 2014-03-06 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 40,482 | $24.10 |
| 2014-03-06 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 20,415 | $24.00 |
| 2014-03-06 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 241,471 | $23.24 |
| 2014-03-06 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 31,531 | $23.18 |
| 2014-03-03 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 16,800 | $18.23 |
| 2014-03-03 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 67,200 | $18.21 |
| 2014-02-28 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 42,000 | $18.10 |
| 2014-02-27 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 17,243 | $19.46 |
| 2014-02-27 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 14,953 | $19.26 |
| 2014-02-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 13,000 | $19.72 |
| 2014-02-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 2,000 | $0.00 |
| 2014-02-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 2,000 | $5.19 |
| 2014-02-26 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 32,194 | $19.15 |
| 2014-02-26 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 42,000 | $19.90 |
| 2014-02-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 2,000 | $19.73 |
| 2014-02-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 13,000 | $0.00 |
| 2014-02-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 13,000 | $3.45 |
| 2014-02-20 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 39 | $18.39 |
| 2014-02-20 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 35,280 | $18.40 |
| 2014-02-19 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 6,720 | $18.51 |
| 2014-02-18 | LANPHIER, EDWARD O II | Director, President & CEO | ストックオプション | 売却 | 50,000 | $0.00 |
| 2014-02-18 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 購入 | 50,000 | $5.19 |
| 2014-02-18 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 50,000 | $18.09 |
| 2014-02-18 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 11,172 | $18.11 |
| 2014-02-14 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 15,380 | $18.61 |
| 2014-02-14 | RINGO, WILLIAM R | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2014-02-14 | RINGO, WILLIAM R | Director | ストックオプション | 売却 | 15,000 | $0.00 |
| 2014-02-14 | RINGO, WILLIAM R | Director | 普通株式 | 購入 | 10,000 | $5.03 |
| 2014-02-14 | RINGO, WILLIAM R | Director | 普通株式 | 売却 | 25,000 | $18.06 |
| 2014-02-14 | RINGO, WILLIAM R | Director | 普通株式 | 購入 | 15,000 | $6.05 |
| 2014-02-13 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 15,409 | $18.46 |
| 2014-02-12 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 42,000 | $18.04 |
| 2014-02-11 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 42,000 | $19.65 |
| 2014-02-10 | WOLFF, HENRY WARD | Exec VP & CFO | ストックオプション | 購入 | 10,000 | $0.00 |
| 2014-02-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 購入 | 10,000 | $3.45 |
| 2014-02-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 10,000 | $19.26 |
| 2014-02-07 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 34,688 | $18.52 |
| 2014-02-06 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 7,312 | $18.42 |
| 2014-02-05 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 10,666 | $18.36 |
| 2014-02-05 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 13,694 | $18.17 |
| 2014-02-05 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 17,640 | $18.21 |
| 2014-02-03 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 購入 | 8,000 | $3.45 |
| 2014-02-03 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 売却 | 15,000 | $18.83 |
| 2014-02-03 | GREGORY, PHILIP D | Vice President, Research & CSO | ストックオプション | 売却 | 8,000 | $0.00 |
| 2014-02-03 | GREGORY, PHILIP D | Vice President, Research & CSO | ストックオプション | 売却 | 7,000 | $0.00 |
| 2014-02-03 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 購入 | 7,000 | $4.11 |
| 2014-01-29 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 8,275 | $5.00 |
| 2014-01-29 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 8,275 | $3.90 |
| 2014-01-29 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 8,275 | $7.00 |
| 2014-01-29 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 8,275 | $2.60 |
| 2014-01-27 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 13,000 | $3.45 |
| 2014-01-27 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 2,000 | $18.73 |
| 2014-01-27 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 2,000 | $0.00 |
| 2014-01-27 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 13,000 | $0.00 |
| 2014-01-27 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 2,000 | $5.19 |
| 2014-01-27 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 13,000 | $18.56 |
| 2014-01-15 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 購入 | 5,281 | $6.39 |
| 2014-01-15 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 購入 | 44,719 | $6.39 |
| 2014-01-15 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 50,000 | $18.51 |
| 2014-01-15 | LANPHIER, EDWARD O II | Director, President & CEO | ストックオプション | 売却 | 5,281 | $0.00 |
| 2014-01-15 | LANPHIER, EDWARD O II | Director, President & CEO | ストックオプション | 売却 | 44,719 | $0.00 |
| 2014-01-15 | CLEVELAND, PAUL B | Director | 普通株式 | 売却 | 8,333 | $18.68 |
| 2014-01-15 | CLEVELAND, PAUL B | Director | ストックオプション | 売却 | 8,333 | $0.00 |
| 2014-01-15 | CLEVELAND, PAUL B | Director | 普通株式 | 購入 | 8,333 | $5.03 |
| 2014-01-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 購入 | 10,000 | $3.45 |
| 2014-01-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 10,000 | $18.69 |
| 2014-01-10 | WOLFF, HENRY WARD | Exec VP & CFO | ストックオプション | 購入 | 10,000 | $0.00 |
| 2014-01-09 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner. | 普通株式 | 売却 | 44,957 | $18.28 |
| 2014-01-09 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner. | 普通株式 | 売却 | 27,483 | $18.47 |
| 2014-01-02 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 売却 | 15,000 | $13.56 |
| 2014-01-02 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 購入 | 7,000 | $4.11 |
| 2014-01-02 | GREGORY, PHILIP D | Vice President, Research & CSO | ストックオプション | 売却 | 7,000 | $0.00 |
| 2014-01-02 | GREGORY, PHILIP D | Vice President, Research & CSO | ストックオプション | 売却 | 8,000 | $0.00 |
| 2014-01-02 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 購入 | 8,000 | $3.45 |
| 2013-12-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 13,000 | $3.45 |
| 2013-12-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 2,000 | $0.00 |
| 2013-12-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 13,000 | $0.00 |
| 2013-12-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 2,000 | $14.22 |
| 2013-12-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 2,000 | $5.19 |
| 2013-12-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 13,000 | $14.39 |
| 2013-12-18 | LANPHIER, EDWARD O II | Director, President & CEO | ストックオプション | 売却 | 50,000 | $0.00 |
| 2013-12-18 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 50,000 | $12.47 |
| 2013-12-18 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 購入 | 50,000 | $6.39 |
| 2013-12-13 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner. | 普通株式 | 購入 | 5,040 | $12.09 |
| 2013-12-12 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 23,000 | $0.00 |
| 2013-12-12 | WOLFF, HENRY WARD | Exec VP & CFO | ストックオプション | 購入 | 70,000 | $0.00 |
| 2013-12-12 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 20,872 | $12.12 |
| 2013-12-12 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 購入 | 35,000 | $0.00 |
| 2013-12-12 | NICHOL, GEOFFREY | Executive Vice President, R&D | ストックオプション | 購入 | 70,000 | $0.00 |
| 2013-12-12 | NICHOL, GEOFFREY | Executive Vice President, R&D | 普通株式 | 売却 | 22,611 | $12.12 |
| 2013-12-12 | NICHOL, GEOFFREY | Executive Vice President, R&D | 普通株式 | 購入 | 35,000 | $0.00 |
| 2013-12-12 | LANPHIER, EDWARD O II | Director, President & CEO | ストックオプション | 購入 | 150,000 | $0.00 |
| 2013-12-12 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 57,398 | $12.12 |
| 2013-12-12 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 購入 | 35,000 | $0.00 |
| 2013-12-12 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 売却 | 15,653 | $12.12 |
| 2013-12-12 | GREGORY, PHILIP D | Vice President, Research & CSO | ストックオプション | 購入 | 70,000 | $0.00 |
| 2013-12-12 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 14,783 | $12.12 |
| 2013-12-12 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 購入 | 46,000 | $0.00 |
| 2013-12-12 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 購入 | 75,000 | $0.00 |
| 2013-12-12 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner. | 普通株式 | 購入 | 9,600 | $12.09 |
| 2013-12-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 10,000 | $11.97 |
| 2013-12-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 購入 | 10,000 | $3.45 |
| 2013-12-10 | WOLFF, HENRY WARD | Exec VP & CFO | ストックオプション | 売却 | 10,000 | $0.00 |
| 2013-12-02 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 購入 | 8,000 | $3.45 |
| 2013-12-02 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 売却 | 15,000 | $11.66 |
| 2013-12-02 | GREGORY, PHILIP D | Vice President, Research & CSO | ストックオプション | 売却 | 8,000 | $0.00 |
| 2013-12-02 | GREGORY, PHILIP D | Vice President, Research & CSO | ストックオプション | 売却 | 7,000 | $0.00 |
| 2013-12-02 | CLEVELAND, PAUL B | Director | 普通株式 | 売却 | 10,000 | $11.64 |
| 2013-12-02 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 購入 | 7,000 | $4.11 |
| 2013-12-02 | CLEVELAND, PAUL B | Director | 普通株式 | 購入 | 10,000 | $6.41 |
| 2013-12-02 | CLEVELAND, PAUL B | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2013-11-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 3,000 | $11.83 |
| 2013-11-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 3,000 | $5.19 |
| 2013-11-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 12,000 | $11.83 |
| 2013-11-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 2,000 | $3.45 |
| 2013-11-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 10,000 | $3.61 |
| 2013-11-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 2,000 | $0.00 |
| 2013-11-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 3,000 | $0.00 |
| 2013-11-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 10,000 | $0.00 |
| 2013-11-15 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 25,000 | $10.11 |
| 2013-11-13 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 購入 | 10,000 | $3.45 |
| 2013-11-13 | WOLFF, HENRY WARD | Exec VP & CFO | ストックオプション | 売却 | 10,000 | $0.00 |
| 2013-11-13 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 10,000 | $10.00 |
| 2013-11-05 | GREGORY, PHILIP D | Vice President, Research & CSO | ストックオプション | 売却 | 7,000 | $0.00 |
| 2013-11-05 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 購入 | 7,000 | $4.11 |
| 2013-11-05 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 売却 | 7,000 | $10.00 |
| 2013-11-01 | GREGORY, PHILIP D | Vice President, Research & CSO | ストックオプション | 売却 | 8,000 | $0.00 |
| 2013-11-01 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 売却 | 8,000 | $9.26 |
| 2013-11-01 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 購入 | 8,000 | $3.45 |
| 2013-10-28 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 10,000 | $3.61 |
| 2013-10-28 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 2,000 | $0.00 |
| 2013-10-28 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 10,000 | $0.00 |
| 2013-10-28 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 3,000 | $0.00 |
| 2013-10-28 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 3,000 | $5.19 |
| 2013-10-28 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 3,000 | $10.39 |
| 2013-10-28 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 12,000 | $10.39 |
| 2013-10-28 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 2,000 | $3.45 |
| 2013-10-21 | CLEVELAND, PAUL B | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2013-10-21 | CLEVELAND, PAUL B | Director | 普通株式 | 購入 | 10,000 | $4.54 |
| 2013-10-21 | CLEVELAND, PAUL B | Director | 普通株式 | 売却 | 10,000 | $10.93 |
| 2013-10-15 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 25,000 | $11.32 |
| 2013-10-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 購入 | 10,000 | $3.45 |
| 2013-10-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 10,000 | $11.28 |
| 2013-10-10 | WOLFF, HENRY WARD | Exec VP & CFO | ストックオプション | 売却 | 10,000 | $0.00 |
| 2013-10-03 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 13,500 | $0.00 |
| 2013-10-01 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 購入 | 8,000 | $3.45 |
| 2013-10-01 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 購入 | 7,000 | $5.19 |
| 2013-10-01 | GREGORY, PHILIP D | Vice President, Research & CSO | ストックオプション | 売却 | 7,000 | $0.00 |
| 2013-10-01 | GREGORY, PHILIP D | Vice President, Research & CSO | ストックオプション | 売却 | 8,000 | $0.00 |
| 2013-10-01 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 売却 | 15,000 | $10.54 |
| 2013-09-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 3,000 | $10.56 |
| 2013-09-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 10,000 | $0.00 |
| 2013-09-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 2,000 | $0.00 |
| 2013-09-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 3,000 | $0.00 |
| 2013-09-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 10,000 | $3.61 |
| 2013-09-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 2,000 | $3.45 |
| 2013-09-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 12,000 | $10.57 |
| 2013-09-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 3,000 | $5.19 |
| 2013-09-16 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 25,000 | $11.29 |
| 2013-09-10 | WOLFF, HENRY WARD | Exec VP & CFO | ストックオプション | 売却 | 10,000 | $0.00 |
| 2013-09-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 10,000 | $10.86 |
| 2013-09-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 購入 | 10,000 | $3.45 |
| 2013-09-03 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 売却 | 15,000 | $10.33 |
| 2013-09-03 | CLEVELAND, PAUL B | Director | 普通株式 | 売却 | 7,278 | $10.30 |
| 2013-09-03 | CLEVELAND, PAUL B | Director | 普通株式 | 購入 | 7,278 | $2.04 |
| 2013-09-03 | GREGORY, PHILIP D | Vice President, Research & CSO | ストックオプション | 売却 | 8,000 | $0.00 |
| 2013-09-03 | GREGORY, PHILIP D | Vice President, Research & CSO | ストックオプション | 売却 | 7,000 | $0.00 |
| 2013-09-03 | CLEVELAND, PAUL B | Director | ストックオプション | 売却 | 7,278 | $0.00 |
| 2013-09-03 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 購入 | 8,000 | $3.45 |
| 2013-09-03 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 購入 | 7,000 | $5.19 |
| 2013-08-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 2,000 | $10.04 |
| 2013-08-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 2,000 | $0.00 |
| 2013-08-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 2,000 | $5.19 |
| 2013-08-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 11,000 | $10.04 |
| 2013-08-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 1,000 | $3.45 |
| 2013-08-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 1,000 | $0.00 |
| 2013-08-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 10,000 | $0.00 |
| 2013-08-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 10,000 | $3.61 |
| 2013-08-15 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 25,000 | $10.12 |
| 2013-08-13 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 購入 | 10,000 | $3.45 |
| 2013-08-13 | WOLFF, HENRY WARD | Exec VP & CFO | ストックオプション | 売却 | 10,000 | $0.00 |
| 2013-08-13 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 10,000 | $10.00 |
| 2013-08-01 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 購入 | 8,000 | $3.45 |
| 2013-08-01 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 購入 | 7,000 | $5.19 |
| 2013-08-01 | GREGORY, PHILIP D | Vice President, Research & CSO | ストックオプション | 売却 | 8,000 | $0.00 |
| 2013-08-01 | GREGORY, PHILIP D | Vice President, Research & CSO | ストックオプション | 売却 | 7,000 | $0.00 |
| 2013-08-01 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 売却 | 15,000 | $9.89 |
| 2013-07-29 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 購入 | 4,000 | $5.19 |
| 2013-07-29 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 購入 | 3,000 | $4.92 |
| 2013-07-29 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 売却 | 7,000 | $10.06 |
| 2013-07-29 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 購入 | 8,000 | $3.45 |
| 2013-07-29 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 売却 | 8,000 | $10.02 |
| 2013-07-29 | GREGORY, PHILIP D | Vice President, Research & CSO | ストックオプション | 売却 | 3,000 | $0.00 |
| 2013-07-29 | GREGORY, PHILIP D | Vice President, Research & CSO | ストックオプション | 売却 | 4,000 | $0.00 |
| 2013-07-29 | GREGORY, PHILIP D | Vice President, Research & CSO | ストックオプション | 売却 | 8,000 | $0.00 |
| 2013-07-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 2,000 | $10.12 |
| 2013-07-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 10,000 | $0.00 |
| 2013-07-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 1,000 | $0.00 |
| 2013-07-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 2,000 | $0.00 |
| 2013-07-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 10,000 | $3.61 |
| 2013-07-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 1,000 | $3.45 |
| 2013-07-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 11,000 | $10.08 |
| 2013-07-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 2,000 | $5.19 |
| 2013-07-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 2,000 | $10.12 |
| 2013-07-25 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 4,071 | $9.51 |
| 2013-07-25 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 191,999 | $9.50 |
| 2013-07-25 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 76,800 | $10.00 |
| 2013-07-25 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 76,800 | $9.91 |
| 2013-07-25 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 19,200 | $10.00 |
| 2013-07-23 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 5,012 | $9.37 |
| 2013-07-22 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 76,801 | $9.56 |
| 2013-07-22 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 23,042 | $9.60 |
| 2013-07-22 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 11,520 | $9.57 |
| 2013-07-19 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 4,532 | $9.85 |
| 2013-07-19 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 76,800 | $9.85 |
| 2013-07-19 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 105,522 | $9.85 |
| 2013-07-19 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 23,040 | $9.77 |
| 2013-07-18 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 74,035 | $10.02 |
| 2013-07-17 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 購入 | 19,200 | $9.79 |
| 2013-07-17 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 29,070 | $10.21 |
| 2013-07-17 | RA, CAPITAL MANAGEMENT, LLC | Former 10% Owner | 普通株式 | 売却 | 19,200 | $10.24 |
| 2013-07-17 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 25,000 | $10.00 |
| 2013-07-17 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 購入 | 10,000 | $3.45 |
| 2013-07-17 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 10,000 | $10.00 |
| 2013-07-17 | WOLFF, HENRY WARD | Exec VP & CFO | ストックオプション | 売却 | 10,000 | $0.00 |
| 2013-07-15 | CLEVELAND, PAUL B | Director | 普通株式 | 売却 | 8,000 | $9.59 |
| 2013-07-15 | CLEVELAND, PAUL B | Director | 普通株式 | 購入 | 8,000 | $2.04 |
| 2013-07-15 | CLEVELAND, PAUL B | Director | ストックオプション | 購入 | 8,000 | $0.00 |
| 2013-06-12 | DILLY, STEPHEN GEORGE | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2013-06-12 | RINGO, WILLIAM R | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2013-06-12 | RAMASASTRY, SAIRA | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2013-06-12 | MENTO, STEVEN J | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2013-06-12 | CLEVELAND, PAUL B | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2013-06-12 | LARSON, JOHN WILLIAM | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2013-06-03 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 購入 | 3,000 | $3.45 |
| 2013-06-03 | GREGORY, PHILIP D | Vice President, Research & CSO | ストックオプション | 売却 | 3,000 | $0.00 |
| 2013-06-03 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 売却 | 3,000 | $7.88 |
| 2013-05-28 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 15,000 | $3.61 |
| 2013-05-28 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 15,000 | $0.00 |
| 2013-05-28 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 15,000 | $8.32 |
| 2013-05-07 | LARSON, JOHN WILLIAM | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2013-05-07 | LARSON, JOHN WILLIAM | Director | 普通株式 | 購入 | 10,000 | $2.45 |
| 2013-05-01 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 購入 | 6,000 | $3.45 |
| 2013-05-01 | GREGORY, PHILIP D | Vice President, Research & CSO | ストックオプション | 売却 | 6,000 | $0.00 |
| 2013-05-01 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 売却 | 6,000 | $10.09 |
| 2013-04-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 15,000 | $10.72 |
| 2013-04-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 15,000 | $3.61 |
| 2013-04-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 15,000 | $0.00 |
| 2013-04-16 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 190 | $10.00 |
| 2013-04-15 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 5,000 | $10.00 |
| 2013-04-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 10,000 | $10.00 |
| 2013-04-10 | WOLFF, HENRY WARD | Exec VP & CFO | ストックオプション | 売却 | 10,000 | $0.00 |
| 2013-04-10 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 購入 | 10,000 | $3.45 |
| 2013-04-01 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 売却 | 6,000 | $9.54 |
| 2013-04-01 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 購入 | 6,000 | $3.45 |
| 2013-04-01 | GREGORY, PHILIP D | Vice President, Research & CSO | ストックオプション | 売却 | 6,000 | $0.00 |
| 2013-03-28 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 12,000 | $0.00 |
| 2013-03-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 9,200 | $0.00 |
| 2013-03-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 5,800 | $3.61 |
| 2013-03-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 9,200 | $3.61 |
| 2013-03-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 15,000 | $9.18 |
| 2013-03-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 5,800 | $0.00 |
| 2013-03-01 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 売却 | 6,000 | $10.00 |
| 2013-03-01 | GREGORY, PHILIP D | Vice President, Research & CSO | ストックオプション | 売却 | 6,000 | $0.00 |
| 2013-03-01 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 購入 | 6,000 | $4.92 |
| 2013-02-28 | WOLFF, HENRY WARD | Exec VP & CFO | ストックオプション | 売却 | 10,000 | $0.00 |
| 2013-02-28 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 購入 | 10,000 | $3.45 |
| 2013-02-28 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 10,000 | $10.00 |
| 2013-02-28 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 25,000 | $10.00 |
| 2013-02-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 15,000 | $0.00 |
| 2013-02-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 15,000 | $8.64 |
| 2013-02-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 15,000 | $3.61 |
| 2013-02-01 | GREGORY, PHILIP D | Vice President, Research & CSO | ストックオプション | 売却 | 6,000 | $0.00 |
| 2013-02-01 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 購入 | 6,000 | $4.92 |
| 2013-02-01 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 売却 | 6,000 | $9.53 |
| 2013-01-28 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 15,000 | $3.61 |
| 2013-01-28 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 15,000 | $0.00 |
| 2013-01-28 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 15,000 | $9.68 |
| 2013-01-24 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 300 | $10.00 |
| 2013-01-23 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 購入 | 8,000 | $3.45 |
| 2013-01-23 | WOLFF, HENRY WARD | Exec VP & CFO | ストックオプション | 売却 | 8,000 | $0.00 |
| 2013-01-23 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 8,300 | $10.00 |
| 2013-01-23 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 10,000 | $10.00 |
| 2013-01-02 | GREGORY, PHILIP D | Vice President, Research & CSO | ストックオプション | 売却 | 6,000 | $0.00 |
| 2013-01-02 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 売却 | 6,000 | $6.05 |
| 2013-01-02 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 購入 | 6,000 | $4.92 |
| 2012-12-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 15,000 | $5.92 |
| 2012-12-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 15,000 | $3.61 |
| 2012-12-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 15,000 | $0.00 |
| 2012-12-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 2,000 | $5.94 |
| 2012-12-10 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 売却 | 12,000 | $6.00 |
| 2012-12-10 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 購入 | 12,000 | $4.92 |
| 2012-12-10 | GREGORY, PHILIP D | Vice President, Research & CSO | ストックオプション | 購入 | 12,000 | $0.00 |
| 2012-12-06 | LANPHIER, EDWARD O II | Director, President & CEO | ストックオプション | 購入 | 250,000 | $0.00 |
| 2012-12-06 | GREGORY, PHILIP D | Vice President, Research & CSO | 普通株式 | 購入 | 40,000 | $0.00 |
| 2012-12-06 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 購入 | 45,000 | $0.00 |
| 2012-12-06 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 購入 | 180,000 | $0.00 |
| 2012-12-06 | GREGORY, PHILIP D | Vice President, Research & CSO | ストックオプション | 購入 | 80,000 | $0.00 |
| 2012-12-06 | WOLFF, HENRY WARD | Exec VP & CFO | ストックオプション | 購入 | 90,000 | $0.00 |
| 2012-12-06 | NICHOL, GEOFFREY | Executive Vice President, R&D | 普通株式 | 購入 | 55,000 | $0.00 |
| 2012-12-06 | NICHOL, GEOFFREY | Executive Vice President, R&D | ストックオプション | 購入 | 110,000 | $0.00 |
| 2012-12-06 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 35,000 | $0.00 |
| 2012-12-06 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 購入 | 70,000 | $0.00 |
| 2012-12-03 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 1,000 | $5.48 |
| 2012-12-03 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 100 | $5.63 |
| 2012-12-03 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 300 | $5.62 |
| 2012-12-03 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 100 | $5.60 |
| 2012-12-03 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 400 | $5.70 |
| 2012-12-03 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 3,195 | $5.54 |
| 2012-12-03 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 7,500 | $5.71 |
| 2012-12-03 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 1,805 | $5.61 |
| 2012-12-03 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 600 | $5.69 |
| 2012-11-27 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 15,000 | $3.61 |
| 2012-11-27 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 15,000 | $0.00 |
| 2012-11-27 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 15,000 | $5.60 |
| 2012-11-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 4,736 | $5.33 |
| 2012-11-01 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 15,000 | $5.52 |
| 2012-10-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 15,000 | $0.00 |
| 2012-10-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 15,000 | $3.61 |
| 2012-10-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 15,000 | $5.69 |
| 2012-10-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 5,000 | $5.72 |
| 2012-10-17 | GREGORY, PHILIP D | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 6,000 | $0.00 |
| 2012-10-17 | GREGORY, PHILIP D | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 6,000 | $6.00 |
| 2012-10-17 | GREGORY, PHILIP D | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 6,000 | $4.92 |
| 2012-10-15 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 14 | $5.71 |
| 2012-10-15 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 1,000 | $5.72 |
| 2012-10-15 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 1,500 | $5.62 |
| 2012-10-15 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 300 | $5.69 |
| 2012-10-15 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 1,500 | $5.62 |
| 2012-10-15 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 500 | $5.69 |
| 2012-10-15 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 186 | $5.70 |
| 2012-10-01 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 506 | $6.16 |
| 2012-10-01 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 300 | $6.15 |
| 2012-10-01 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 6,676 | $6.21 |
| 2012-10-01 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 1,869 | $6.17 |
| 2012-10-01 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 1,258 | $6.18 |
| 2012-10-01 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 995 | $6.19 |
| 2012-10-01 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 58 | $6.20 |
| 2012-10-01 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 1,398 | $6.24 |
| 2012-10-01 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 1,940 | $6.22 |
| 2012-09-05 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 15,000 | $5.60 |
| 2012-09-05 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 15,000 | $3.61 |
| 2012-09-05 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 15,000 | $0.00 |
| 2012-09-04 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 500 | $5.22 |
| 2012-09-04 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 100 | $5.35 |
| 2012-09-04 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 99 | $5.34 |
| 2012-09-04 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 100 | $5.23 |
| 2012-09-04 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 100 | $5.20 |
| 2012-09-04 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 601 | $5.21 |
| 2012-09-04 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 100 | $5.24 |
| 2012-09-04 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 299 | $5.25 |
| 2012-09-04 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 1,068 | $5.26 |
| 2012-09-04 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 429 | $5.27 |
| 2012-09-04 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 2,702 | $5.30 |
| 2012-09-04 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 803 | $5.31 |
| 2012-09-04 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 7,603 | $5.32 |
| 2012-09-04 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 196 | $5.32 |
| 2012-09-04 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 300 | $5.33 |
| 2012-08-27 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 250 | $5.23 |
| 2012-08-27 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 200 | $5.22 |
| 2012-08-27 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 1,630 | $5.16 |
| 2012-08-27 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 1,170 | $5.15 |
| 2012-08-27 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 200 | $5.17 |
| 2012-08-27 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 550 | $5.21 |
| 2012-08-27 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 1,000 | $5.22 |
| 2012-08-01 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 100 | $5.24 |
| 2012-08-01 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 7,900 | $5.28 |
| 2012-08-01 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 700 | $5.20 |
| 2012-08-01 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 2,400 | $5.21 |
| 2012-08-01 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 1,500 | $5.27 |
| 2012-08-01 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 100 | $5.26 |
| 2012-08-01 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 1,500 | $5.22 |
| 2012-08-01 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 800 | $5.23 |
| 2012-07-27 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 15,000 | $0.00 |
| 2012-07-27 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 15,000 | $5.60 |
| 2012-07-27 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 15,000 | $3.61 |
| 2012-07-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 1,500 | $5.04 |
| 2012-07-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 1,000 | $5.12 |
| 2012-07-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 1,500 | $5.09 |
| 2012-07-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 500 | $4.99 |
| 2012-07-26 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 500 | $5.02 |
| 2012-07-02 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 359 | $5.27 |
| 2012-07-02 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 1,541 | $5.20 |
| 2012-07-02 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 1,927 | $5.23 |
| 2012-07-02 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 100 | $5.23 |
| 2012-07-02 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 100 | $5.24 |
| 2012-07-02 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 4,100 | $5.24 |
| 2012-07-02 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 1,600 | $5.25 |
| 2012-07-02 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 2,500 | $5.26 |
| 2012-07-02 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 400 | $5.21 |
| 2012-07-02 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 100 | $5.22 |
| 2012-07-02 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 100 | $5.28 |
| 2012-07-02 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 300 | $5.29 |
| 2012-07-02 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 200 | $5.20 |
| 2012-07-02 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 100 | $5.21 |
| 2012-07-02 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 100 | $5.22 |
| 2012-07-02 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 1,473 | $5.22 |
| 2012-06-21 | RAMASASTRY, SAIRA | Director | ストックオプション | 購入 | 50,000 | $0.00 |
| 2012-06-21 | MENTO, STEVEN J | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2012-06-21 | RINGO, WILLIAM R | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2012-06-21 | DILLY, STEPHEN GEORGE | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2012-06-21 | LARSON, JOHN WILLIAM | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2012-06-21 | CLEVELAND, PAUL B | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2012-06-15 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 15,000 | $5.00 |
| 2012-06-13 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 11,000 | $0.00 |
| 2012-01-28 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 売却 | 15,000 | $0.00 |
| 2012-01-28 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 売却 | 15,000 | $9.68 |
| 2012-01-28 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 15,000 | $3.61 |
| 2011-12-30 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 2,234 | $2.84 |
| 2011-12-08 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 購入 | 150,000 | $0.00 |
| 2011-12-08 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 購入 | 75,000 | $0.00 |
| 2011-12-08 | NICHOL, GEOFFREY | Executive Vice President, R&D | 普通株式 | 購入 | 75,000 | $0.00 |
| 2011-12-08 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 購入 | 50,000 | $0.00 |
| 2011-12-08 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 購入 | 25,000 | $0.00 |
| 2011-12-08 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | 普通株式 | 購入 | 50,000 | $0.00 |
| 2011-09-30 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 2,234 | $4.35 |
| 2011-09-09 | GREGORY, PHILIP D | CSO & Vice President, Research | ストックオプション | 売却 | 2,500 | $0.00 |
| 2011-09-09 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 購入 | 2,500 | $3.45 |
| 2011-09-09 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 購入 | 2,500 | $3.00 |
| 2011-09-09 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 2,500 | $6.00 |
| 2011-07-11 | NICHOL, GEOFFREY | Executive Vice President, R&D | ストックオプション | 購入 | 300,000 | $0.00 |
| 2011-07-07 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 購入 | 4,000 | $5.19 |
| 2011-07-07 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | ストックオプション | 売却 | 4,000 | $0.00 |
| 2011-07-07 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 4,000 | $6.47 |
| 2011-07-01 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 購入 | 15,000 | $3.45 |
| 2011-07-01 | GREGORY, PHILIP D | CSO & Vice President, Research | ストックオプション | 売却 | 15,000 | $0.00 |
| 2011-07-01 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 15,000 | $6.00 |
| 2011-06-30 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 2,234 | $5.89 |
| 2011-06-06 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | ストックオプション | 売却 | 4,000 | $0.00 |
| 2011-06-06 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 購入 | 4,000 | $5.19 |
| 2011-06-06 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 4,000 | $6.52 |
| 2011-06-01 | MENTO, STEVEN J | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2011-06-01 | WIGGANS, THOMAS G | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2011-06-01 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 106 | $6.82 |
| 2011-06-01 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 15,000 | $0.00 |
| 2011-06-01 | LARSON, JOHN WILLIAM | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2011-06-01 | RINGO, WILLIAM R | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2011-06-01 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 購入 | 15,000 | $3.45 |
| 2011-06-01 | GREGORY, PHILIP D | CSO & Vice President, Research | ストックオプション | 売却 | 15,000 | $0.00 |
| 2011-06-01 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 13,894 | $6.80 |
| 2011-06-01 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 1,000 | $6.81 |
| 2011-06-01 | DILLY, STEPHEN GEORGE | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2011-06-01 | CLEVELAND, PAUL B | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2011-05-05 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 購入 | 4,000 | $5.19 |
| 2011-05-05 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 4,000 | $6.74 |
| 2011-05-05 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | ストックオプション | 売却 | 4,000 | $0.00 |
| 2011-05-02 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 7,400 | $7.34 |
| 2011-05-02 | GREGORY, PHILIP D | CSO & Vice President, Research | ストックオプション | 売却 | 15,000 | $0.00 |
| 2011-05-02 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 2,200 | $7.34 |
| 2011-05-02 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 800 | $7.33 |
| 2011-05-02 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 299 | $7.32 |
| 2011-05-02 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 101 | $7.32 |
| 2011-05-02 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 1,600 | $7.31 |
| 2011-05-02 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 1,000 | $7.31 |
| 2011-05-02 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 1,500 | $7.30 |
| 2011-05-02 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 購入 | 15,000 | $3.45 |
| 2011-05-02 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 100 | $7.35 |
| 2011-04-25 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 購入 | 4,209 | $3.00 |
| 2011-04-25 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 1,648 | $7.50 |
| 2011-04-25 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 1,600 | $7.52 |
| 2011-04-25 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 90 | $7.53 |
| 2011-04-25 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 7,005 | $7.54 |
| 2011-04-25 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 200 | $7.55 |
| 2011-04-25 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 4,900 | $7.55 |
| 2011-04-25 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 800 | $7.56 |
| 2011-04-25 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 300 | $7.56 |
| 2011-04-25 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 1,705 | $7.56 |
| 2011-04-25 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 200 | $7.59 |
| 2011-04-25 | GREGORY, PHILIP D | CSO & Vice President, Research | ストックオプション | 売却 | 4,209 | $0.00 |
| 2011-04-25 | GREGORY, PHILIP D | CSO & Vice President, Research | ストックオプション | 売却 | 10,791 | $0.00 |
| 2011-04-25 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 購入 | 10,791 | $3.45 |
| 2011-04-25 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 985 | $7.51 |
| 2011-04-21 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 1,600 | $7.71 |
| 2011-04-21 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 1,500 | $7.67 |
| 2011-04-21 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 381 | $7.66 |
| 2011-04-21 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 1,000 | $7.73 |
| 2011-04-21 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 1,728 | $7.75 |
| 2011-04-21 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | ストックオプション | 売却 | 8,000 | $0.00 |
| 2011-04-21 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 購入 | 8,000 | $5.19 |
| 2011-04-21 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 1,269 | $7.68 |
| 2011-04-21 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 100 | $7.64 |
| 2011-04-21 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 322 | $7.65 |
| 2011-04-21 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 100 | $7.70 |
| 2011-03-31 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 2,235 | $8.33 |
| 2011-03-01 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 1,000 | $8.30 |
| 2011-03-01 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 200 | $8.34 |
| 2011-03-01 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 200 | $8.33 |
| 2011-03-01 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 40 | $8.24 |
| 2011-03-01 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 360 | $8.25 |
| 2011-03-01 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 700 | $8.26 |
| 2011-02-28 | CLEVELAND, PAUL B | Director | 普通株式 | 売却 | 1,388 | $9.00 |
| 2011-02-28 | CLEVELAND, PAUL B | Director | 普通株式 | 購入 | 1,388 | $2.04 |
| 2011-02-28 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 2,500 | $9.00 |
| 2011-02-28 | CLEVELAND, PAUL B | Director | ストックオプション | 売却 | 1,388 | $0.00 |
| 2011-02-01 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 300 | $7.98 |
| 2011-02-01 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 1,900 | $7.97 |
| 2011-02-01 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 300 | $7.96 |
| 2011-01-03 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 2,500 | $6.80 |
| 2010-12-31 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 2,234 | $6.64 |
| 2010-12-22 | CLEVELAND, PAUL B | Director | 普通株式 | 売却 | 22,037 | $7.00 |
| 2010-12-22 | CLEVELAND, PAUL B | Director | 普通株式 | 購入 | 10,000 | $4.10 |
| 2010-12-22 | CLEVELAND, PAUL B | Director | 普通株式 | 売却 | 10,000 | $7.00 |
| 2010-12-22 | CLEVELAND, PAUL B | Director | ストックオプション | 売却 | 22,037 | $0.00 |
| 2010-12-22 | CLEVELAND, PAUL B | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2010-12-22 | CLEVELAND, PAUL B | Director | 普通株式 | 購入 | 22,037 | $2.04 |
| 2010-12-20 | CLEVELAND, PAUL B | Director | ストックオプション | 売却 | 11,297 | $0.00 |
| 2010-12-20 | CLEVELAND, PAUL B | Director | 普通株式 | 購入 | 11,297 | $2.04 |
| 2010-12-20 | CLEVELAND, PAUL B | Director | 普通株式 | 売却 | 11,297 | $7.00 |
| 2010-12-08 | WOLFF, HENRY WARD | Exec VP & CFO | ストックオプション | 購入 | 150,000 | $0.00 |
| 2010-12-08 | LANPHIER, EDWARD O II | Director, President & CEO | ストックオプション | 購入 | 300,000 | $0.00 |
| 2010-12-08 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 購入 | 100,000 | $0.00 |
| 2010-12-08 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | ストックオプション | 購入 | 50,000 | $0.00 |
| 2010-12-08 | GREGORY, PHILIP D | CSO & Vice President, Research | ストックオプション | 購入 | 100,000 | $0.00 |
| 2010-12-08 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 2,500 | $6.00 |
| 2010-09-30 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 2,239 | $3.43 |
| 2010-08-30 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 購入 | 10,000 | $3.01 |
| 2010-08-30 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 購入 | 9,000 | $3.00 |
| 2010-06-30 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 2,234 | $3.71 |
| 2010-06-02 | CLEVELAND, PAUL B | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2010-06-02 | MENTO, STEVEN J | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2010-06-02 | LARSON, JOHN WILLIAM | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2010-06-02 | GERBER, WILLIAM G | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2010-06-02 | WIGGANS, THOMAS G | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2010-05-03 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 200 | $6.23 |
| 2010-05-03 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 1,493 | $6.29 |
| 2010-05-03 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 300 | $6.28 |
| 2010-05-03 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 300 | $6.25 |
| 2010-05-03 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 7 | $6.21 |
| 2010-05-03 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 200 | $6.24 |
| 2010-04-16 | RINGO, WILLIAM R | Director | ストックオプション | 購入 | 50,000 | $0.00 |
| 2010-04-16 | RINGO, WILLIAM R | Director | 普通株式 | 購入 | 10,000 | $6.05 |
| 2010-04-14 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 500 | $6.12 |
| 2010-04-14 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 1,000 | $6.14 |
| 2010-04-14 | GREGORY, PHILIP D | CSO & Vice President, Research | 普通株式 | 売却 | 1,000 | $6.17 |
| 2010-03-31 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 2,233 | $5.42 |
| 2010-03-31 | DILLY, STEPHEN GEORGE | Director | ストックオプション | 購入 | 50,000 | $0.00 |
| 2009-12-31 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 2,233 | $5.92 |
| 2009-12-07 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 購入 | 100,000 | $0.00 |
| 2009-12-07 | WOLFF, HENRY WARD | Exec VP & CFO | ストックオプション | 購入 | 200,000 | $0.00 |
| 2009-12-07 | GREGORY, PHILIP D | CSO & Vice President, Research | ストックオプション | 購入 | 100,000 | $0.00 |
| 2009-12-07 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | ストックオプション | 購入 | 50,000 | $0.00 |
| 2009-12-07 | LANPHIER, EDWARD O II | Director, President & CEO | ストックオプション | 購入 | 300,000 | $0.00 |
| 2009-09-30 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 2,233 | $8.21 |
| 2009-06-30 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 2,234 | $4.94 |
| 2009-06-04 | MENTO, STEVEN J | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2009-06-04 | LARSON, JOHN WILLIAM | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2009-06-04 | GERBER, WILLIAM G | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2009-06-04 | WIGGANS, THOMAS G | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2009-06-04 | CLEVELAND, PAUL B | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2009-03-31 | WOLFF, HENRY WARD | Exec VP & CFO | 普通株式 | 売却 | 2,237 | $4.23 |
| 2008-12-31 | WOLFF, HENRY WARD | Exe VP & CFO | 普通株式 | 売却 | 8,938 | $3.48 |
| 2008-12-10 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 購入 | 200,000 | $0.00 |
| 2008-12-10 | WOLFF, HENRY WARD | Exe VP & CFO | ストックオプション | 購入 | 300,000 | $0.00 |
| 2008-12-10 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | ストックオプション | 購入 | 100,000 | $0.00 |
| 2008-12-10 | LANPHIER, EDWARD O II | Director, President & CEO | ストックオプション | 購入 | 350,000 | $0.00 |
| 2008-12-10 | GREGORY, PHILIP D | Vice President, Research | ストックオプション | 購入 | 200,000 | $0.00 |
| 2008-11-19 | CLEVELAND, PAUL B | Director | ストックオプション | 売却 | 50,000 | $0.00 |
| 2008-09-02 | GREGORY, PHILIP D | Vice President, Research | ストックオプション | 売却 | 1,000 | $0.00 |
| 2008-09-02 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 売却 | 1,000 | $10.12 |
| 2008-09-02 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 購入 | 1,000 | $3.00 |
| 2008-08-15 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 売却 | 100 | $10.63 |
| 2008-08-15 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 売却 | 200 | $10.64 |
| 2008-08-15 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 売却 | 150 | $10.65 |
| 2008-08-15 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 売却 | 5,600 | $10.60 |
| 2008-08-15 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 売却 | 1,500 | $10.61 |
| 2008-08-15 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 売却 | 200 | $10.62 |
| 2008-08-15 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 売却 | 100 | $10.75 |
| 2008-08-15 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 売却 | 100 | $10.74 |
| 2008-08-15 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 売却 | 100 | $10.73 |
| 2008-08-15 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 売却 | 400 | $10.70 |
| 2008-08-15 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 売却 | 600 | $10.68 |
| 2008-08-15 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 売却 | 450 | $10.67 |
| 2008-08-15 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 売却 | 100 | $10.66 |
| 2008-08-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 300 | $10.59 |
| 2008-08-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 2,500 | $10.60 |
| 2008-08-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 15,563 | $10.60 |
| 2008-08-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,600 | $10.61 |
| 2008-08-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,900 | $10.62 |
| 2008-08-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 237 | $10.63 |
| 2008-08-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 300 | $10.64 |
| 2008-08-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 2,300 | $10.65 |
| 2008-08-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 300 | $10.66 |
| 2008-08-15 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 売却 | 300 | $10.59 |
| 2008-08-15 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 売却 | 100 | $10.76 |
| 2008-08-01 | GREGORY, PHILIP D | Vice President, Research | ストックオプション | 売却 | 680 | $0.00 |
| 2008-08-01 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 売却 | 900 | $10.85 |
| 2008-08-01 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 売却 | 100 | $10.80 |
| 2008-08-01 | GREGORY, PHILIP D | Vice President, Research | ストックオプション | 売却 | 320 | $0.00 |
| 2008-07-31 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 5,700 | $11.02 |
| 2008-07-30 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 3,500 | $11.04 |
| 2008-07-29 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 2,200 | $11.28 |
| 2008-07-29 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 1,000 | $11.28 |
| 2008-07-29 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 3,000 | $11.29 |
| 2008-07-29 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 2,500 | $11.20 |
| 2008-07-29 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 500 | $11.20 |
| 2008-07-29 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 2,000 | $11.21 |
| 2008-07-29 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 1,000 | $11.20 |
| 2008-07-29 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 1,000 | $11.21 |
| 2008-07-29 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 1,000 | $11.22 |
| 2008-07-29 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 1,200 | $11.22 |
| 2008-07-29 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 1,600 | $11.22 |
| 2008-07-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 200 | $10.29 |
| 2008-07-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 200 | $10.30 |
| 2008-07-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 11,600 | $10.30 |
| 2008-07-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 200 | $10.31 |
| 2008-07-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,115 | $10.32 |
| 2008-07-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 300 | $10.33 |
| 2008-07-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 2,600 | $10.13 |
| 2008-07-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 273 | $10.15 |
| 2008-07-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 900 | $10.16 |
| 2008-07-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,000 | $10.18 |
| 2008-07-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 400 | $10.21 |
| 2008-07-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 100 | $10.21 |
| 2008-07-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 227 | $10.21 |
| 2008-07-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 100 | $10.24 |
| 2008-07-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 2,886 | $10.24 |
| 2008-07-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 814 | $10.25 |
| 2008-07-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 100 | $10.26 |
| 2008-07-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 100 | $10.26 |
| 2008-07-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 100 | $10.26 |
| 2008-07-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,320 | $10.27 |
| 2008-07-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 161 | $10.28 |
| 2008-07-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 304 | $10.29 |
| 2008-07-01 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 購入 | 1,000 | $4.92 |
| 2008-07-01 | GREGORY, PHILIP D | Vice President, Research | ストックオプション | 売却 | 1,000 | $0.00 |
| 2008-07-01 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 売却 | 500 | $10.01 |
| 2008-07-01 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 売却 | 500 | $10.00 |
| 2008-06-30 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 100 | $10.30 |
| 2008-06-30 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 12,000 | $10.00 |
| 2008-06-30 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 5,000 | $10.05 |
| 2008-06-30 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 5,500 | $10.15 |
| 2008-06-30 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 153 | $10.24 |
| 2008-06-30 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 200 | $10.26 |
| 2008-06-30 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 100 | $10.27 |
| 2008-06-30 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,100 | $10.28 |
| 2008-06-30 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 747 | $10.29 |
| 2008-06-30 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 100 | $10.30 |
| 2008-06-04 | GERBER, WILLIAM G | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2008-06-04 | MENTO, STEVEN J | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2008-06-04 | LIU, MARGARET | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2008-06-04 | LARSON, JOHN WILLIAM | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2008-06-04 | WOOD, MICHAEL C | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2008-06-04 | WIGGANS, THOMAS G | Director | ストックオプション | 売却 | 50,000 | $0.00 |
| 2008-06-02 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 売却 | 349 | $10.70 |
| 2008-06-02 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 売却 | 551 | $10.71 |
| 2008-06-02 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 売却 | 100 | $10.74 |
| 2008-06-02 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 購入 | 1,000 | $4.92 |
| 2008-06-02 | GREGORY, PHILIP D | Vice President, Research | ストックオプション | 売却 | 1,000 | $0.00 |
| 2008-05-20 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 200 | $13.61 |
| 2008-05-20 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 100 | $13.50 |
| 2008-05-20 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 1,950 | $13.30 |
| 2008-05-20 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 2,000 | $13.37 |
| 2008-05-20 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 900 | $13.33 |
| 2008-05-20 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 1,900 | $13.39 |
| 2008-05-20 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 1,300 | $13.35 |
| 2008-05-20 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 500 | $13.34 |
| 2008-05-20 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 100 | $13.28 |
| 2008-05-20 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 200 | $13.56 |
| 2008-05-20 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 1,000 | $13.50 |
| 2008-05-20 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 300 | $13.76 |
| 2008-05-20 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 購入 | 15,000 | $5.19 |
| 2008-05-20 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 100 | $13.29 |
| 2008-05-20 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 1,000 | $13.26 |
| 2008-05-20 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 100 | $13.27 |
| 2008-05-20 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 100 | $13.38 |
| 2008-05-20 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 200 | $13.47 |
| 2008-05-20 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 300 | $13.40 |
| 2008-05-20 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 650 | $13.32 |
| 2008-05-20 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 100 | $13.32 |
| 2008-05-20 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 1,500 | $13.31 |
| 2008-05-20 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 300 | $13.28 |
| 2008-05-20 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 200 | $13.38 |
| 2008-05-20 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | ストックオプション | 売却 | 15,000 | $0.00 |
| 2008-05-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 352 | $13.27 |
| 2008-05-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 200 | $13.50 |
| 2008-05-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 100 | $13.51 |
| 2008-05-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 631 | $13.24 |
| 2008-05-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 300 | $13.26 |
| 2008-05-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 550 | $13.49 |
| 2008-05-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,100 | $13.25 |
| 2008-05-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 814 | $13.29 |
| 2008-05-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,724 | $13.30 |
| 2008-05-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 967 | $13.31 |
| 2008-05-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,648 | $13.32 |
| 2008-05-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 800 | $13.33 |
| 2008-05-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 300 | $13.34 |
| 2008-05-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 100 | $13.35 |
| 2008-05-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 2,532 | $13.36 |
| 2008-05-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,980 | $13.37 |
| 2008-05-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 700 | $13.38 |
| 2008-05-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 600 | $13.39 |
| 2008-05-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 3,700 | $13.40 |
| 2008-05-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 400 | $13.42 |
| 2008-05-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 500 | $13.43 |
| 2008-05-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,815 | $13.44 |
| 2008-05-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 100 | $13.45 |
| 2008-05-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 900 | $13.46 |
| 2008-05-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 500 | $13.47 |
| 2008-05-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,687 | $13.48 |
| 2008-05-01 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 購入 | 1,000 | $4.92 |
| 2008-05-01 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 売却 | 1,000 | $12.69 |
| 2008-05-01 | GREGORY, PHILIP D | Vice President, Research | ストックオプション | 売却 | 1,000 | $0.00 |
| 2008-04-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 100 | $11.43 |
| 2008-04-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 700 | $11.44 |
| 2008-04-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,800 | $11.45 |
| 2008-04-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 900 | $11.46 |
| 2008-04-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 600 | $11.47 |
| 2008-04-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,000 | $11.41 |
| 2008-04-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 600 | $11.48 |
| 2008-04-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,600 | $11.50 |
| 2008-04-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 600 | $11.51 |
| 2008-04-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 800 | $11.52 |
| 2008-04-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 600 | $11.53 |
| 2008-04-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 500 | $11.54 |
| 2008-04-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,500 | $11.55 |
| 2008-04-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,100 | $11.56 |
| 2008-04-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 700 | $11.58 |
| 2008-04-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 600 | $11.60 |
| 2008-04-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 500 | $11.61 |
| 2008-04-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 300 | $11.62 |
| 2008-04-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 200 | $11.63 |
| 2008-04-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 200 | $11.27 |
| 2008-04-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 200 | $11.28 |
| 2008-04-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 200 | $11.28 |
| 2008-04-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 200 | $11.29 |
| 2008-04-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 100 | $11.32 |
| 2008-04-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 200 | $11.34 |
| 2008-04-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 143 | $11.34 |
| 2008-04-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 200 | $11.35 |
| 2008-04-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,118 | $11.35 |
| 2008-04-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 3,339 | $11.36 |
| 2008-04-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 800 | $11.37 |
| 2008-04-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,400 | $11.38 |
| 2008-04-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 200 | $11.39 |
| 2008-04-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 600 | $11.40 |
| 2008-04-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 300 | $11.65 |
| 2008-04-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 400 | $11.66 |
| 2008-04-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 700 | $11.57 |
| 2008-04-01 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 売却 | 700 | $10.20 |
| 2008-04-01 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 売却 | 100 | $10.22 |
| 2008-04-01 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 売却 | 200 | $10.17 |
| 2008-04-01 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 購入 | 1,000 | $4.92 |
| 2008-04-01 | GREGORY, PHILIP D | Vice President, Research | ストックオプション | 売却 | 1,000 | $0.00 |
| 2008-03-19 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 売却 | 1,000 | $10.01 |
| 2008-03-19 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 購入 | 1,000 | $4.92 |
| 2008-03-19 | GREGORY, PHILIP D | Vice President, Research | ストックオプション | 売却 | 1,000 | $0.00 |
| 2008-03-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,400 | $8.72 |
| 2008-03-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,303 | $8.77 |
| 2008-03-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,000 | $8.76 |
| 2008-03-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 100 | $8.76 |
| 2008-03-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 200 | $8.76 |
| 2008-03-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 100 | $8.88 |
| 2008-03-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,000 | $8.58 |
| 2008-03-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 100 | $8.29 |
| 2008-03-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 3,105 | $8.60 |
| 2008-03-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 695 | $8.61 |
| 2008-03-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 700 | $8.62 |
| 2008-03-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 200 | $8.63 |
| 2008-03-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 500 | $8.64 |
| 2008-03-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,701 | $8.65 |
| 2008-03-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,499 | $8.66 |
| 2008-03-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 300 | $8.67 |
| 2008-03-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 600 | $8.68 |
| 2008-03-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 200 | $8.69 |
| 2008-03-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 200 | $8.70 |
| 2008-03-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 200 | $8.71 |
| 2008-03-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 2,300 | $8.73 |
| 2008-03-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 2,000 | $8.74 |
| 2008-03-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,500 | $8.75 |
| 2008-03-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 100 | $8.76 |
| 2008-03-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 200 | $8.84 |
| 2008-03-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 200 | $8.85 |
| 2008-03-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 400 | $8.86 |
| 2008-03-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 200 | $8.87 |
| 2008-03-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,600 | $8.78 |
| 2008-03-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 697 | $8.79 |
| 2008-03-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 100 | $8.79 |
| 2008-03-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 200 | $8.80 |
| 2008-03-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 400 | $8.83 |
| 2008-03-06 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 100 | $12.69 |
| 2008-03-06 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 5,000 | $12.60 |
| 2008-03-06 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 300 | $12.71 |
| 2008-03-06 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 200 | $12.67 |
| 2008-03-06 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 10,000 | $12.40 |
| 2008-03-06 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 3,400 | $12.64 |
| 2008-03-06 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 600 | $12.70 |
| 2008-03-06 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 400 | $12.68 |
| 2008-03-06 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 4,600 | $12.57 |
| 2008-03-06 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 400 | $12.50 |
| 2008-03-05 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 10,000 | $12.67 |
| 2008-03-05 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 25,000 | $12.55 |
| 2008-03-05 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 購入 | 400,000 | $0.17 |
| 2008-03-05 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 5,000 | $12.72 |
| 2008-03-05 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 5,000 | $12.77 |
| 2008-03-05 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 5,000 | $12.74 |
| 2008-03-05 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | ストックオプション | 売却 | 400,000 | $0.00 |
| 2008-02-21 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 600 | $12.16 |
| 2008-02-21 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 655 | $12.21 |
| 2008-02-21 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 335 | $12.05 |
| 2008-02-21 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 100 | $12.14 |
| 2008-02-21 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 100 | $12.13 |
| 2008-02-21 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 500 | $12.15 |
| 2008-02-21 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 799 | $12.12 |
| 2008-02-21 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 100 | $12.10 |
| 2008-02-21 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 500 | $12.09 |
| 2008-02-21 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 272 | $12.02 |
| 2008-02-21 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 300 | $12.07 |
| 2008-02-21 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 900 | $12.06 |
| 2008-02-21 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 864 | $12.04 |
| 2008-02-21 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 564 | $12.08 |
| 2008-02-21 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 200 | $12.01 |
| 2008-02-21 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 200 | $12.27 |
| 2008-02-21 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 100 | $12.03 |
| 2008-02-21 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 200 | $12.17 |
| 2008-02-21 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 100 | $12.20 |
| 2008-02-21 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 100 | $12.24 |
| 2008-02-21 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 購入 | 10,000 | $5.19 |
| 2008-02-21 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | ストックオプション | 売却 | 10,000 | $0.00 |
| 2008-02-21 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 2,511 | $12.00 |
| 2008-02-20 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 購入 | 5,000 | $5.19 |
| 2008-02-20 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | ストックオプション | 売却 | 5,000 | $0.00 |
| 2008-02-20 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 5,000 | $12.00 |
| 2008-02-15 | LANPHIER, EDWARD O II | Director, President & Chief Exec Officer | 普通株式 | 売却 | 1,300 | $11.67 |
| 2008-02-15 | LANPHIER, EDWARD O II | Director, President & Chief Exec Officer | 普通株式 | 売却 | 100 | $11.81 |
| 2008-02-15 | LANPHIER, EDWARD O II | Director, President & Chief Exec Officer | 普通株式 | 売却 | 1,600 | $11.81 |
| 2008-02-15 | LANPHIER, EDWARD O II | Director, President & Chief Exec Officer | 普通株式 | 売却 | 200 | $11.82 |
| 2008-02-15 | LANPHIER, EDWARD O II | Director, President & Chief Exec Officer | 普通株式 | 売却 | 1,700 | $11.84 |
| 2008-02-15 | LANPHIER, EDWARD O II | Director, President & Chief Exec Officer | 普通株式 | 売却 | 100 | $11.85 |
| 2008-02-15 | LANPHIER, EDWARD O II | Director, President & Chief Exec Officer | 普通株式 | 売却 | 300 | $11.89 |
| 2008-02-15 | LANPHIER, EDWARD O II | Director, President & Chief Exec Officer | 普通株式 | 売却 | 1,300 | $11.90 |
| 2008-02-15 | LANPHIER, EDWARD O II | Director, President & Chief Exec Officer | 普通株式 | 売却 | 2,100 | $11.90 |
| 2008-02-15 | LANPHIER, EDWARD O II | Director, President & Chief Exec Officer | 普通株式 | 売却 | 300 | $11.91 |
| 2008-02-15 | LANPHIER, EDWARD O II | Director, President & Chief Exec Officer | 普通株式 | 売却 | 400 | $11.92 |
| 2008-02-15 | LANPHIER, EDWARD O II | Director, President & Chief Exec Officer | 普通株式 | 売却 | 2,900 | $12.00 |
| 2008-02-15 | LANPHIER, EDWARD O II | Director, President & Chief Exec Officer | 普通株式 | 売却 | 800 | $11.66 |
| 2008-02-15 | LANPHIER, EDWARD O II | Director, President & Chief Exec Officer | 普通株式 | 売却 | 100 | $11.66 |
| 2008-02-15 | LANPHIER, EDWARD O II | Director, President & Chief Exec Officer | 普通株式 | 売却 | 500 | $11.85 |
| 2008-02-15 | LANPHIER, EDWARD O II | Director, President & Chief Exec Officer | 普通株式 | 売却 | 500 | $11.87 |
| 2008-02-15 | LANPHIER, EDWARD O II | Director, President & Chief Exec Officer | 普通株式 | 売却 | 100 | $11.88 |
| 2008-02-15 | LANPHIER, EDWARD O II | Director, President & Chief Exec Officer | 普通株式 | 売却 | 100 | $11.88 |
| 2008-02-15 | LANPHIER, EDWARD O II | Director, President & Chief Exec Officer | 普通株式 | 売却 | 700 | $11.65 |
| 2008-02-15 | LANPHIER, EDWARD O II | Director, President & Chief Exec Officer | 普通株式 | 売却 | 100 | $11.64 |
| 2008-02-15 | LANPHIER, EDWARD O II | Director, President & Chief Exec Officer | 普通株式 | 売却 | 1,400 | $11.63 |
| 2008-02-15 | LANPHIER, EDWARD O II | Director, President & Chief Exec Officer | 普通株式 | 売却 | 200 | $11.66 |
| 2008-02-15 | LANPHIER, EDWARD O II | Director, President & Chief Exec Officer | 普通株式 | 売却 | 700 | $11.80 |
| 2008-02-15 | LANPHIER, EDWARD O II | Director, President & Chief Exec Officer | 普通株式 | 売却 | 400 | $11.66 |
| 2008-02-15 | LANPHIER, EDWARD O II | Director, President & Chief Exec Officer | 普通株式 | 売却 | 6,900 | $11.60 |
| 2008-02-15 | LANPHIER, EDWARD O II | Director, President & Chief Exec Officer | 普通株式 | 売却 | 200 | $11.62 |
| 2008-02-14 | ZANTE, GREG | Vice President, Fin. & Admin. | 普通株式 | 購入 | 1,041 | $4.11 |
| 2008-02-14 | ZANTE, GREG | VP, Finance & Administration | ストックオプション | 売却 | 100 | $0.00 |
| 2008-02-14 | ZANTE, GREG | VP, Finance & Administration | 普通株式 | 売却 | 100 | $12.00 |
| 2008-02-14 | ZANTE, GREG | VP, Finance & Administration | 普通株式 | 購入 | 100 | $4.11 |
| 2008-02-14 | ZANTE, GREG | Vice President, Fin. & Admin. | 普通株式 | 購入 | 3,959 | $5.19 |
| 2008-02-14 | ZANTE, GREG | Vice President, Fin. & Admin. | ストックオプション | 売却 | 1,041 | $0.00 |
| 2008-02-14 | ZANTE, GREG | Vice President, Fin. & Admin. | 普通株式 | 売却 | 250 | $12.00 |
| 2008-02-14 | ZANTE, GREG | Vice President, Fin. & Admin. | 普通株式 | 売却 | 4,750 | $12.02 |
| 2008-02-14 | ZANTE, GREG | Vice President, Fin. & Admin. | ストックオプション | 売却 | 3,959 | $0.00 |
| 2008-01-15 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 購入 | 20,000 | $4.11 |
| 2008-01-15 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | ストックオプション | 売却 | 15,000 | $0.00 |
| 2008-01-15 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 1,000 | $13.01 |
| 2008-01-15 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 2,000 | $12.78 |
| 2008-01-15 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 1,000 | $12.76 |
| 2008-01-15 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 1,800 | $12.75 |
| 2008-01-15 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 1,091 | $12.89 |
| 2008-01-15 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 909 | $12.81 |
| 2008-01-15 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 200 | $12.83 |
| 2008-01-15 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 1,600 | $12.88 |
| 2008-01-15 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 100 | $12.86 |
| 2008-01-15 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 900 | $12.85 |
| 2008-01-15 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 400 | $12.84 |
| 2008-01-15 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 2,000 | $13.40 |
| 2008-01-15 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 1,000 | $13.42 |
| 2008-01-15 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 売却 | 1,000 | $13.22 |
| 2008-01-15 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | 普通株式 | 購入 | 15,000 | $5.19 |
| 2008-01-15 | LANPHIER, EDWARD O II | Director, President & Chief Exec Officer | 普通株式 | 売却 | 25,000 | $13.13 |
| 2008-01-15 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 売却 | 20,000 | $0.00 |
| 2008-01-08 | ZANTE, GREG | Vice President, Fin. & Admin. | 普通株式 | 売却 | 1,000 | $12.98 |
| 2008-01-08 | ZANTE, GREG | Vice President, Fin. & Admin. | 普通株式 | 売却 | 300 | $12.72 |
| 2008-01-08 | ZANTE, GREG | Vice President, Fin. & Admin. | 普通株式 | 売却 | 400 | $12.67 |
| 2008-01-08 | ZANTE, GREG | Vice President, Fin. & Admin. | 普通株式 | 売却 | 200 | $12.66 |
| 2008-01-08 | ZANTE, GREG | Vice President, Fin. & Admin. | 普通株式 | 購入 | 1,042 | $4.11 |
| 2008-01-08 | ZANTE, GREG | Vice President, Fin. & Admin. | ストックオプション | 売却 | 3,350 | $0.00 |
| 2008-01-08 | ZANTE, GREG | Vice President, Fin. & Admin. | ストックオプション | 売却 | 1,042 | $0.00 |
| 2008-01-08 | ZANTE, GREG | Vice President, Fin. & Admin. | ストックオプション | 売却 | 608 | $0.00 |
| 2008-01-08 | ZANTE, GREG | Vice President, Fin. & Admin. | 普通株式 | 購入 | 3,350 | $4.92 |
| 2008-01-08 | ZANTE, GREG | Vice President, Fin. & Admin. | 普通株式 | 売却 | 100 | $12.60 |
| 2008-01-08 | ZANTE, GREG | Vice President, Fin. & Admin. | 普通株式 | 売却 | 100 | $12.59 |
| 2008-01-08 | ZANTE, GREG | Vice President, Fin. & Admin. | 普通株式 | 売却 | 1,200 | $12.86 |
| 2008-01-08 | ZANTE, GREG | Vice President, Fin. & Admin. | 普通株式 | 購入 | 608 | $5.19 |
| 2008-01-08 | ZANTE, GREG | Vice President, Fin. & Admin. | 普通株式 | 売却 | 200 | $12.63 |
| 2008-01-08 | ZANTE, GREG | Vice President, Fin. & Admin. | 普通株式 | 売却 | 1,200 | $13.00 |
| 2008-01-08 | ZANTE, GREG | Vice President, Fin. & Admin. | 普通株式 | 売却 | 300 | $12.99 |
| 2007-12-17 | LANPHIER, EDWARD O II | Director, President & Chief Exec Officer | 普通株式 | 売却 | 25,000 | $13.13 |
| 2007-12-12 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 購入 | 100,000 | $0.00 |
| 2007-12-12 | GREGORY, PHILIP D | Vice President, Research | ストックオプション | 購入 | 90,000 | $0.00 |
| 2007-12-12 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | ストックオプション | 購入 | 30,000 | $0.00 |
| 2007-12-12 | LANPHIER, EDWARD O II | Director, President & Chief Exec Officer | ストックオプション | 購入 | 250,000 | $0.00 |
| 2007-12-12 | ZANTE, GREG | Vice President, Fin. & Admin. | ストックオプション | 購入 | 50,000 | $0.00 |
| 2007-12-07 | ZANTE, GREG | Vice President, Fin. & Admin. | 普通株式 | 売却 | 249 | $15.53 |
| 2007-12-07 | ZANTE, GREG | Vice President, Fin. & Admin. | 普通株式 | 売却 | 400 | $15.98 |
| 2007-12-07 | ZANTE, GREG | Vice President, Fin. & Admin. | 普通株式 | 購入 | 1,650 | $4.92 |
| 2007-12-07 | ZANTE, GREG | Vice President, Fin. & Admin. | 普通株式 | 売却 | 800 | $15.59 |
| 2007-12-07 | ZANTE, GREG | Vice President, Fin. & Admin. | 普通株式 | 売却 | 100 | $15.57 |
| 2007-12-07 | ZANTE, GREG | Vice President, Fin. & Admin. | 普通株式 | 売却 | 101 | $15.56 |
| 2007-12-07 | ZANTE, GREG | Vice President, Fin. & Admin. | 普通株式 | 購入 | 3,350 | $4.11 |
| 2007-12-07 | ZANTE, GREG | Vice President, Fin. & Admin. | ストックオプション | 売却 | 3,350 | $0.00 |
| 2007-12-07 | ZANTE, GREG | Vice President, Fin. & Admin. | ストックオプション | 売却 | 1,650 | $0.00 |
| 2007-12-07 | ZANTE, GREG | Vice President, Fin. & Admin. | 普通株式 | 売却 | 100 | $16.02 |
| 2007-12-07 | ZANTE, GREG | Vice President, Fin. & Admin. | 普通株式 | 売却 | 1,900 | $15.97 |
| 2007-12-07 | ZANTE, GREG | Vice President, Fin. & Admin. | 普通株式 | 売却 | 150 | $15.80 |
| 2007-12-07 | ZANTE, GREG | Vice President, Fin. & Admin. | 普通株式 | 売却 | 100 | $15.70 |
| 2007-12-07 | ZANTE, GREG | Vice President, Fin. & Admin. | 普通株式 | 売却 | 200 | $15.69 |
| 2007-12-07 | ZANTE, GREG | Vice President, Fin. & Admin. | 普通株式 | 売却 | 900 | $15.68 |
| 2007-12-06 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 購入 | 5,000 | $4.92 |
| 2007-12-06 | GERBER, WILLIAM G | Director | 普通株式 | 売却 | 6,100 | $16.00 |
| 2007-12-06 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 売却 | 5,000 | $16.00 |
| 2007-12-06 | GREGORY, PHILIP D | Vice President, Research | ストックオプション | 売却 | 5,000 | $0.00 |
| 2007-12-03 | WOLFF, HENRY WARD | Executive VP and CFO | 普通株式 | 購入 | 100,000 | $0.00 |
| 2007-12-03 | WOLFF, HENRY WARD | Executive VP and CFO | ストックオプション | 購入 | 300,000 | $0.00 |
| 2007-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 100 | $14.82 |
| 2007-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 458 | $14.60 |
| 2007-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 900 | $14.61 |
| 2007-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 500 | $14.63 |
| 2007-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 600 | $14.70 |
| 2007-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 200 | $14.71 |
| 2007-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,173 | $14.72 |
| 2007-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 563 | $14.73 |
| 2007-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 300 | $14.75 |
| 2007-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 400 | $14.77 |
| 2007-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 200 | $14.78 |
| 2007-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 600 | $14.80 |
| 2007-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 500 | $14.81 |
| 2007-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 100 | $14.83 |
| 2007-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 300 | $14.84 |
| 2007-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 2,100 | $14.85 |
| 2007-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,900 | $14.86 |
| 2007-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 200 | $14.87 |
| 2007-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 900 | $14.87 |
| 2007-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,000 | $14.88 |
| 2007-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 600 | $14.89 |
| 2007-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 900 | $14.90 |
| 2007-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,100 | $14.97 |
| 2007-11-15 | MENTO, STEVEN J | Director | 普通株式 | 売却 | 13,600 | $14.75 |
| 2007-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 300 | $14.98 |
| 2007-11-15 | MENTO, STEVEN J | Director | 普通株式 | 売却 | 13,600 | $14.75 |
| 2007-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 500 | $14.91 |
| 2007-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 700 | $14.92 |
| 2007-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 900 | $14.93 |
| 2007-11-15 | MENTO, STEVEN J | Director | 普通株式 | 売却 | 1,400 | $14.76 |
| 2007-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 800 | $14.94 |
| 2007-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 3,306 | $14.95 |
| 2007-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 2,900 | $14.96 |
| 2007-11-15 | MENTO, STEVEN J | Director | 普通株式 | 売却 | 1,400 | $14.76 |
| 2007-11-14 | MENTO, STEVEN J | Director | 普通株式 | 売却 | 1,400 | $14.90 |
| 2007-11-14 | MENTO, STEVEN J | Director | 普通株式 | 売却 | 1,000 | $14.84 |
| 2007-11-14 | MENTO, STEVEN J | Director | 普通株式 | 売却 | 1,000 | $14.82 |
| 2007-11-14 | MENTO, STEVEN J | Director | 普通株式 | 売却 | 1,000 | $14.75 |
| 2007-11-14 | MENTO, STEVEN J | Director | 普通株式 | 売却 | 3,900 | $14.87 |
| 2007-11-14 | MENTO, STEVEN J | Director | 普通株式 | 売却 | 500 | $14.77 |
| 2007-11-14 | MENTO, STEVEN J | Director | 普通株式 | 売却 | 3,000 | $14.91 |
| 2007-11-14 | MENTO, STEVEN J | Director | 普通株式 | 売却 | 2,200 | $14.86 |
| 2007-11-14 | MENTO, STEVEN J | Director | 普通株式 | 売却 | 2,000 | $14.78 |
| 2007-11-14 | MENTO, STEVEN J | Director | 普通株式 | 売却 | 2,000 | $14.77 |
| 2007-11-14 | MENTO, STEVEN J | Director | 普通株式 | 売却 | 1,500 | $14.89 |
| 2007-11-13 | MENTO, STEVEN J | Director | 普通株式 | 購入 | 10,000 | $7.73 |
| 2007-11-13 | MENTO, STEVEN J | Director | ストックオプション | 売却 | 4,166 | $0.00 |
| 2007-11-13 | MENTO, STEVEN J | Director | ストックオプション | 売却 | 40,278 | $0.00 |
| 2007-11-13 | MENTO, STEVEN J | Director | 普通株式 | 購入 | 4,166 | $7.28 |
| 2007-11-13 | MENTO, STEVEN J | Director | 普通株式 | 購入 | 40,278 | $3.87 |
| 2007-11-13 | MENTO, STEVEN J | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2007-11-08 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 1,269 | $19.01 |
| 2007-11-08 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 1,231 | $18.96 |
| 2007-11-08 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 400 | $19.03 |
| 2007-11-08 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 7,100 | $18.90 |
| 2007-11-08 | ZANTE, GREG | Vice President, Fin. & Admin. | 普通株式 | 売却 | 642 | $18.03 |
| 2007-11-08 | ZANTE, GREG | Vice President, Fin. & Admin. | 普通株式 | 購入 | 3,750 | $3.00 |
| 2007-11-08 | ZANTE, GREG | Vice President, Fin. & Admin. | 普通株式 | 売却 | 3,750 | $18.03 |
| 2007-11-08 | ZANTE, GREG | Vice President, Fin. & Admin. | 普通株式 | 購入 | 8,108 | $4.11 |
| 2007-11-08 | ZANTE, GREG | Vice President, Fin. & Admin. | 普通株式 | 売却 | 8,108 | $18.03 |
| 2007-11-08 | ZANTE, GREG | Vice President, Fin. & Admin. | ストックオプション | 売却 | 3,750 | $0.00 |
| 2007-11-08 | ZANTE, GREG | Vice President, Fin. & Admin. | ストックオプション | 売却 | 8,108 | $0.00 |
| 2007-11-08 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 売却 | 6,171 | $17.58 |
| 2007-11-08 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 購入 | 6,171 | $3.00 |
| 2007-11-08 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 売却 | 13,620 | $17.58 |
| 2007-11-08 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 購入 | 13,620 | $3.00 |
| 2007-11-08 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 購入 | 5,000 | $3.99 |
| 2007-11-08 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 売却 | 5,000 | $17.58 |
| 2007-11-08 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 購入 | 209 | $4.11 |
| 2007-11-08 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 売却 | 209 | $17.58 |
| 2007-11-08 | GREGORY, PHILIP D | Vice President, Research | ストックオプション | 売却 | 13,620 | $0.00 |
| 2007-11-08 | GREGORY, PHILIP D | Vice President, Research | ストックオプション | 売却 | 6,171 | $0.00 |
| 2007-11-08 | GREGORY, PHILIP D | Vice President, Research | ストックオプション | 売却 | 5,000 | $0.00 |
| 2007-11-08 | GREGORY, PHILIP D | Vice President, Research | ストックオプション | 売却 | 209 | $0.00 |
| 2007-10-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 7,600 | $16.20 |
| 2007-10-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 100 | $15.92 |
| 2007-10-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 400 | $16.32 |
| 2007-10-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 700 | $16.10 |
| 2007-10-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 200 | $16.12 |
| 2007-10-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 4,867 | $15.90 |
| 2007-10-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 33 | $15.89 |
| 2007-10-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,100 | $16.11 |
| 2007-10-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,600 | $16.33 |
| 2007-10-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 3,000 | $16.13 |
| 2007-10-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 3,000 | $16.30 |
| 2007-10-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 2,400 | $16.25 |
| 2007-09-24 | GERBER, WILLIAM G | Director | 普通株式 | 売却 | 5,000 | $13.34 |
| 2007-09-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 4,920 | $12.13 |
| 2007-09-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 2,165 | $12.00 |
| 2007-09-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 300 | $12.01 |
| 2007-09-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 2,515 | $12.01 |
| 2007-09-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,325 | $12.02 |
| 2007-09-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 400 | $12.03 |
| 2007-09-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 26 | $12.08 |
| 2007-09-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 100 | $12.07 |
| 2007-09-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 631 | $12.06 |
| 2007-09-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 4,849 | $12.05 |
| 2007-09-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 554 | $12.04 |
| 2007-09-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 175 | $12.04 |
| 2007-09-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 160 | $12.03 |
| 2007-09-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 2,242 | $12.15 |
| 2007-09-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 200 | $12.17 |
| 2007-09-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 200 | $12.19 |
| 2007-09-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 100 | $12.19 |
| 2007-09-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 2,738 | $12.20 |
| 2007-09-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 100 | $12.21 |
| 2007-09-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 400 | $12.21 |
| 2007-09-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 100 | $12.22 |
| 2007-09-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 800 | $12.10 |
| 2007-08-24 | GERBER, WILLIAM G | Director | 普通株式 | 売却 | 4,554 | $10.87 |
| 2007-08-24 | GERBER, WILLIAM G | Director | 普通株式 | 売却 | 446 | $10.86 |
| 2007-08-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 100 | $10.02 |
| 2007-08-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 7,692 | $10.03 |
| 2007-08-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 14,588 | $10.00 |
| 2007-08-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 220 | $10.01 |
| 2007-08-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 2,400 | $10.03 |
| 2007-07-23 | GERBER, WILLIAM G | Director | 普通株式 | 売却 | 5,000 | $9.66 |
| 2007-07-16 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 25,000 | $10.05 |
| 2007-06-25 | GERBER, WILLIAM G | Director | 普通株式 | 売却 | 5,000 | $8.50 |
| 2007-06-18 | GERBER, WILLIAM G | Director | 普通株式 | 売却 | 5,000 | $8.00 |
| 2007-06-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 463 | $7.38 |
| 2007-06-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 300 | $7.37 |
| 2007-06-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 7,132 | $7.32 |
| 2007-06-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 2,348 | $7.36 |
| 2007-06-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 300 | $7.35 |
| 2007-06-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 2,599 | $7.34 |
| 2007-06-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 7,050 | $7.30 |
| 2007-06-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 508 | $7.29 |
| 2007-06-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 4,200 | $7.28 |
| 2007-06-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 100 | $7.39 |
| 2007-06-07 | MENTO, STEVEN J | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2007-06-07 | WOOD, MICHAEL C | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2007-06-07 | WOLFF, HENRY WARD | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2007-06-07 | LIU, MARGARET | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2007-06-07 | LARSON, JOHN WILLIAM | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2007-06-07 | GERBER, WILLIAM G | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2007-05-21 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 25,000 | $7.32 |
| 2007-05-18 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 12,000 | $7.01 |
| 2007-05-15 | LANPHIER, EDWARD O II | Director, Pres and Chief Ex Officer | 普通株式 | 売却 | 600 | $6.73 |
| 2007-05-15 | LANPHIER, EDWARD O II | Director, Pres and Chief Ex Officer | 普通株式 | 売却 | 500 | $6.71 |
| 2007-05-15 | LANPHIER, EDWARD O II | Director, Pres and Chief Ex Officer | 普通株式 | 売却 | 1,500 | $6.72 |
| 2007-05-15 | LANPHIER, EDWARD O II | Director, Pres and Chief Ex Officer | 普通株式 | 売却 | 2,600 | $6.75 |
| 2007-05-15 | LANPHIER, EDWARD O II | Director, Pres and Chief Ex Officer | 普通株式 | 売却 | 1,400 | $6.76 |
| 2007-05-15 | LANPHIER, EDWARD O II | Director, Pres and Chief Ex Officer | 普通株式 | 売却 | 7,700 | $6.80 |
| 2007-05-15 | LANPHIER, EDWARD O II | Director, Pres and Chief Ex Officer | 普通株式 | 売却 | 10,000 | $6.82 |
| 2007-05-15 | LANPHIER, EDWARD O II | Director, Pres and Chief Ex Officer | 普通株式 | 売却 | 300 | $6.87 |
| 2007-05-15 | LANPHIER, EDWARD O II | Director, Pres and Chief Ex Officer | 普通株式 | 売却 | 100 | $6.88 |
| 2007-05-15 | LANPHIER, EDWARD O II | Director, Pres and Chief Ex Officer | 普通株式 | 売却 | 200 | $6.89 |
| 2007-05-15 | LANPHIER, EDWARD O II | Director, Pres and Chief Ex Officer | 普通株式 | 売却 | 100 | $6.90 |
| 2007-04-16 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 100 | $6.94 |
| 2007-04-16 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 600 | $6.77 |
| 2007-04-16 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 700 | $6.78 |
| 2007-04-16 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 700 | $6.81 |
| 2007-04-16 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 800 | $6.90 |
| 2007-04-16 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,000 | $6.82 |
| 2007-04-16 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 5,000 | $6.96 |
| 2007-04-16 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,500 | $6.75 |
| 2007-04-16 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 4,129 | $7.00 |
| 2007-04-16 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 5,000 | $6.95 |
| 2007-04-16 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 200 | $6.76 |
| 2007-04-16 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 5,100 | $6.91 |
| 2007-04-16 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 71 | $6.80 |
| 2007-04-16 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 100 | $6.93 |
| 2007-03-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 6,944 | $6.65 |
| 2007-03-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,521 | $6.63 |
| 2007-03-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 2,372 | $6.62 |
| 2007-03-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,782 | $6.60 |
| 2007-03-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,500 | $6.71 |
| 2007-03-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 7,330 | $6.70 |
| 2007-03-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 3,551 | $6.69 |
| 2007-02-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 2,100 | $8.10 |
| 2007-02-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 9,100 | $7.95 |
| 2007-02-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 9,400 | $8.00 |
| 2007-02-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,900 | $8.06 |
| 2007-02-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 100 | $8.07 |
| 2007-02-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 500 | $8.08 |
| 2007-02-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 900 | $8.09 |
| 2007-02-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,000 | $8.11 |
| 2007-02-13 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 購入 | 6,000 | $3.20 |
| 2007-02-13 | GREGORY, PHILIP D | Vice President, Research | ストックオプション | 売却 | 6,000 | $0.00 |
| 2007-02-13 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 売却 | 6,000 | $8.18 |
| 2007-02-13 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 売却 | 2,000 | $8.18 |
| 2007-02-02 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 50,000 | $8.70 |
| 2007-02-01 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 25,000 | $8.20 |
| 2007-01-31 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 25,000 | $7.79 |
| 2007-01-30 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 25,000 | $7.43 |
| 2007-01-29 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 25,000 | $7.10 |
| 2007-01-16 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 3,400 | $6.41 |
| 2007-01-16 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 3,866 | $6.34 |
| 2007-01-16 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 6,034 | $6.35 |
| 2007-01-16 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 900 | $6.38 |
| 2007-01-16 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 3,800 | $6.40 |
| 2007-01-16 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 100 | $6.39 |
| 2007-01-16 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 200 | $6.43 |
| 2007-01-16 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 6,700 | $6.42 |
| 2006-12-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 5,200 | $6.52 |
| 2006-12-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 12,295 | $6.50 |
| 2006-12-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 400 | $6.51 |
| 2006-12-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 800 | $6.53 |
| 2006-12-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 100 | $6.54 |
| 2006-12-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 700 | $6.56 |
| 2006-12-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 4,854 | $6.57 |
| 2006-12-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 651 | $6.58 |
| 2006-12-13 | ZANTE, GREG | VP, Finance & Administration | ストックオプション | 購入 | 50,000 | $0.00 |
| 2006-12-13 | LANPHIER, EDWARD O II | Director, President & CEO | ストックオプション | 購入 | 200,000 | $0.00 |
| 2006-12-13 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 購入 | 50,000 | $0.00 |
| 2006-12-13 | GREGORY, PHILIP D | Vice President, Research | ストックオプション | 購入 | 50,000 | $0.00 |
| 2006-12-13 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | ストックオプション | 購入 | 50,000 | $0.00 |
| 2006-12-12 | ZANTE, GREG | VP, Finance & Administration | 普通株式 | 購入 | 12,500 | $4.11 |
| 2006-12-12 | ZANTE, GREG | VP, Finance & Administration | ストックオプション | 売却 | 12,500 | $0.00 |
| 2006-12-12 | ZANTE, GREG | VP, Finance & Administration | 普通株式 | 売却 | 12,500 | $6.98 |
| 2006-12-11 | ZANTE, GREG | VP, Finance & Administration | 普通株式 | 売却 | 2,834 | $7.04 |
| 2006-12-11 | ZANTE, GREG | VP, Finance & Administration | 普通株式 | 売却 | 827 | $7.04 |
| 2006-12-11 | ZANTE, GREG | VP, Finance & Administration | 普通株式 | 購入 | 2,834 | $3.00 |
| 2006-12-11 | ZANTE, GREG | VP, Finance & Administration | 普通株式 | 売却 | 9,583 | $7.04 |
| 2006-12-11 | ZANTE, GREG | VP, Finance & Administration | ストックオプション | 売却 | 2,834 | $0.00 |
| 2006-12-11 | ZANTE, GREG | VP, Finance & Administration | ストックオプション | 売却 | 15,000 | $0.00 |
| 2006-12-11 | ZANTE, GREG | VP, Finance & Administration | ストックオプション | 売却 | 9,583 | $0.00 |
| 2006-12-11 | ZANTE, GREG | VP, Finance & Administration | 普通株式 | 購入 | 15,000 | $4.92 |
| 2006-12-11 | ZANTE, GREG | VP, Finance & Administration | 普通株式 | 売却 | 15,000 | $7.04 |
| 2006-12-11 | ZANTE, GREG | VP, Finance & Administration | 普通株式 | 購入 | 9,583 | $5.19 |
| 2006-12-01 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 20,000 | $7.54 |
| 2006-11-30 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 20,000 | $7.96 |
| 2006-11-28 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 20,000 | $7.77 |
| 2006-11-27 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 20,000 | $7.64 |
| 2006-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 900 | $5.49 |
| 2006-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 600 | $5.48 |
| 2006-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 4,701 | $5.47 |
| 2006-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 2,108 | $5.46 |
| 2006-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 6,191 | $5.45 |
| 2006-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 200 | $5.44 |
| 2006-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 101 | $5.42 |
| 2006-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,720 | $5.41 |
| 2006-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 2,548 | $5.40 |
| 2006-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 431 | $5.39 |
| 2006-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 2,000 | $5.38 |
| 2006-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 100 | $5.36 |
| 2006-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 2,900 | $5.35 |
| 2006-11-15 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 500 | $5.50 |
| 2006-10-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,000 | $5.41 |
| 2006-10-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 2,100 | $5.45 |
| 2006-10-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 2,000 | $5.43 |
| 2006-10-16 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 14,989 | $5.45 |
| 2006-10-16 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 2,433 | $5.46 |
| 2006-10-16 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,978 | $5.47 |
| 2006-10-16 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 500 | $5.50 |
| 2006-09-28 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,800 | $6.08 |
| 2006-09-28 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 700 | $6.10 |
| 2006-09-28 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,750 | $5.70 |
| 2006-09-28 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 2,350 | $5.77 |
| 2006-09-28 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 900 | $5.80 |
| 2006-09-28 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 5,000 | $5.90 |
| 2006-09-28 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 2,500 | $5.91 |
| 2006-09-28 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 10,000 | $5.93 |
| 2006-08-31 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 500 | $5.41 |
| 2006-08-31 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 3,700 | $5.40 |
| 2006-08-31 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 200 | $5.61 |
| 2006-08-31 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 700 | $5.60 |
| 2006-08-31 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 100 | $5.56 |
| 2006-08-31 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,300 | $5.55 |
| 2006-08-31 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 100 | $5.52 |
| 2006-08-31 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 100 | $5.51 |
| 2006-08-31 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 7,600 | $5.50 |
| 2006-08-31 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 1,500 | $5.48 |
| 2006-08-31 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 3,500 | $5.45 |
| 2006-08-31 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 200 | $5.44 |
| 2006-08-31 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 5,500 | $5.42 |
| 2006-06-07 | WOOD, MICHAEL C | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2006-06-07 | LARSON, JOHN WILLIAM | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2006-06-07 | GERBER, WILLIAM G | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2006-06-07 | MENTO, STEVEN J | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2006-06-07 | WOLFF, HENRY WARD | Director | ストックオプション | 購入 | 50,000 | $0.00 |
| 2006-06-07 | LIU, MARGARET | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2006-06-02 | GREGORY, PHILIP D | Vice President, Research | 普通株式 | 売却 | 6,000 | $7.43 |
| 2006-06-01 | ZANTE, GREG | Sr. Director Finance & Admin | 普通株式 | 購入 | 8,000 | $3.00 |
| 2006-06-01 | ZANTE, GREG | Sr. Director Finance & Admin | 普通株式 | 売却 | 8,000 | $7.90 |
| 2006-06-01 | ZANTE, GREG | Sr. Director Finance & Admin | ストックオプション | 購入 | 8,000 | $0.00 |
| 2006-05-30 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 19,000 | $6.61 |
| 2006-05-24 | LANPHIER, EDWARD O II | Director, President & CEO, 10% Owner | 普通株式 | 売却 | 6,000 | $5.38 |
| 2006-05-24 | LANPHIER, EDWARD O II | Director, President & CEO, 10% Owner | 普通株式 | 売却 | 100 | $5.50 |
| 2006-05-24 | LANPHIER, EDWARD O II | Director, President & CEO, 10% Owner | 普通株式 | 売却 | 10,000 | $5.45 |
| 2006-05-24 | LANPHIER, EDWARD O II | Director, President & CEO, 10% Owner | 普通株式 | 売却 | 4,000 | $5.40 |
| 2006-05-24 | LANPHIER, EDWARD O II | Director, President & CEO, 10% Owner | 普通株式 | 売却 | 4,900 | $5.37 |
| 2006-01-31 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 30,000 | $4.76 |
| 2006-01-06 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 20,000 | $4.55 |
| 2005-12-16 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 2,000 | $0.00 |
| 2005-12-16 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 5,000 | $0.00 |
| 2005-12-16 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 500 | $0.00 |
| 2005-12-16 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 3,000 | $0.00 |
| 2005-12-16 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 7,000 | $0.00 |
| 2005-12-16 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 1,000 | $0.00 |
| 2005-12-14 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 20,000 | $4.04 |
| 2005-12-12 | LANPHIER, EDWARD O II | Director, President & CEO | ストックオプション | 購入 | 150,000 | $0.00 |
| 2005-12-12 | ANDO, DALE G | VP, Therapeutic Dev. & CMO | ストックオプション | 購入 | 50,000 | $0.00 |
| 2005-12-12 | GREGORY, PHILIP D | Vice President, Research | ストックオプション | 購入 | 50,000 | $0.00 |
| 2005-12-12 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 20,000 | $4.14 |
| 2005-12-12 | ZANTE, GREG | VP, Finance & Administration | ストックオプション | 購入 | 50,000 | $0.00 |
| 2005-12-12 | ICHIKAWA, DAVID G | Senior VP, Bus. Dev. | ストックオプション | 購入 | 25,000 | $0.00 |
| 2005-12-09 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 20,000 | $4.16 |
| 2005-12-08 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 20,000 | $4.14 |
| 2005-12-07 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 30,000 | $4.05 |
| 2005-12-06 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 30,000 | $4.01 |
| 2005-12-05 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 30,000 | $3.96 |
| 2005-10-05 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 20,000 | $4.58 |
| 2005-10-04 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 20,000 | $4.55 |
| 2005-07-11 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 20,000 | $4.00 |
| 2005-06-06 | LARSON, JOHN WILLIAM | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2005-06-06 | WOOD, MICHAEL C | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2005-06-06 | JACOBY, JON E M | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2005-06-06 | GERBER, WILLIAM G | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2005-05-24 | MENTO, STEVEN J | Director | ストックオプション | 購入 | 50,000 | $3.88 |
| 2005-03-04 | LIU, MARGARET | Director | ストックオプション | 購入 | 50,000 | $5.19 |
| 2005-03-01 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 3,000 | $5.15 |
| 2005-02-25 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 3,000 | $5.17 |
| 2005-02-09 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 3,000 | $5.37 |
| 2005-02-08 | LANPHIER, EDWARD O II | Director, President and CEO | 普通株式 | 売却 | 5,000 | $5.33 |
| 2005-02-07 | LANPHIER, EDWARD O II | Director, President and CEO | 普通株式 | 売却 | 15,000 | $5.43 |
| 2005-02-01 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 3,000 | $5.34 |
| 2005-01-28 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 3,000 | $5.07 |
| 2005-01-19 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 3,000 | $5.31 |
| 2005-01-11 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 3,000 | $5.45 |
| 2005-01-04 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 3,000 | $5.51 |
| 2004-12-29 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 3,000 | $5.80 |
| 2004-12-22 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 3,000 | $5.52 |
| 2004-12-22 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 5,000 | $0.00 |
| 2004-12-22 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 7,000 | $0.00 |
| 2004-12-22 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 1,000 | $0.00 |
| 2004-12-22 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 4,000 | $0.00 |
| 2004-12-22 | LANPHIER, EDWARD O II | Director, President & CEO | 普通株式 | 売却 | 3,000 | $0.00 |
| 2004-12-20 | ZANTE, GREG | Sr. Director Finance & Admin | ストックオプション | 購入 | 20,000 | $0.00 |
| 2004-12-20 | LANPHIER, EDWARD O II | Director, President & CEO | ストックオプション | 購入 | 100,000 | $0.00 |
| 2004-12-20 | CASE, CASEY C | VP, Research & Operations | ストックオプション | 購入 | 20,000 | $0.00 |
| 2004-12-16 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 3,000 | $5.26 |
| 2004-11-24 | LANPHIER, EDWARD O II | Director, President and CEO | 普通株式 | 売却 | 5,000 | $0.00 |
| 2004-10-08 | LANPHIER, EDWARD O II | Director, President and CEO | 普通株式 | 売却 | 2,600 | $5.00 |
| 2004-10-07 | LANPHIER, EDWARD O II | Director, President and CEO | 普通株式 | 売却 | 6,550 | $5.01 |
| 2004-09-29 | ZANTE, GREG | Sr Dir., Finance & Admin | ストックオプション | 売却 | 5,416 | $ |
| 2004-09-29 | ZANTE, GREG | Sr Dir., Finance & Admin | 普通株式 | 売却 | 5,416 | $5.05 |
| 2004-09-29 | ZANTE, GREG | Sr Dir., Finance & Admin | 普通株式 | 購入 | 5,416 | $3.00 |
| 2004-09-29 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 3,000 | $5.06 |
| 2004-09-29 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 3,000 | $5.03 |
| 2004-09-27 | BLUFORD, PETER | VP, Corporate Development | 普通株式 | 売却 | 500 | $5.30 |
| 2004-09-27 | BLUFORD, PETER | VP, Corporate Development | 普通株式 | 売却 | 500 | $5.00 |
| 2004-09-21 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 3,000 | $5.04 |
| 2004-09-20 | BLUFORD, PETER | VP, Corporate Development | 普通株式 | 売却 | 500 | $5.00 |
| 2004-09-17 | LANPHIER, EDWARD O II | Director, President and CEO | 普通株式 | 売却 | 700 | $5.00 |
| 2004-09-16 | LANPHIER, EDWARD O II | Director, President and CEO | 普通株式 | 売却 | 6,900 | $5.11 |
| 2004-09-15 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 3,000 | $5.36 |
| 2004-09-15 | BLUFORD, PETER | VP, Corporate Development | 普通株式 | 売却 | 500 | $5.15 |
| 2004-07-12 | BLUFORD, PETER | VP, Corporate Development | 普通株式 | 売却 | 500 | $5.56 |
| 2004-07-06 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 3,000 | $5.65 |
| 2004-07-06 | BLUFORD, PETER | VP, Corporate Development | 普通株式 | 売却 | 500 | $5.50 |
| 2004-06-30 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 3,000 | $5.90 |
| 2004-06-28 | BLUFORD, PETER | VP, Corporate Development | 普通株式 | 売却 | 500 | $5.64 |
| 2004-06-23 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 3,000 | $5.90 |
| 2004-06-21 | BLUFORD, PETER | VP, Corporate Development | 普通株式 | 売却 | 500 | $5.80 |
| 2004-06-17 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 3,000 | $5.81 |
| 2004-06-14 | BLUFORD, PETER | VP, Corporate Development | 普通株式 | 売却 | 500 | $5.41 |
| 2004-06-10 | RUTTER, WILLIAM J | Director | ストックオプション | 購入 | 10,000 | $5.66 |
| 2004-06-10 | LARSON, JOHN WILLIAM | Director | ストックオプション | 購入 | 10,000 | $5.66 |
| 2004-06-10 | JACOBY, JON E M | Director | ストックオプション | 購入 | 10,000 | $5.66 |
| 2004-06-10 | WOOD, MICHAEL C | Director | ストックオプション | 購入 | 10,000 | $5.66 |
| 2004-06-10 | GERBER, WILLIAM G | Director | ストックオプション | 購入 | 10,000 | $5.66 |
| 2004-06-08 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 3,000 | $6.24 |
| 2004-06-07 | BLUFORD, PETER | VP, Corporate Development | 普通株式 | 売却 | 500 | $6.17 |
| 2004-06-04 | LARSON, JOHN WILLIAM | Director | 普通株式 | 売却 | 3,000 | $6.06 |
| 2004-06-03 | LANPHIER, EDWARD O II | Director, President and CEO | 普通株式 | 売却 | 10,500 | $6.01 |
| 2004-06-02 | LANPHIER, EDWARD O II | Director, President and CEO | 普通株式 | 売却 | 7,500 | $6.04 |
| 2004-06-01 | BLUFORD, PETER | VP, Corporate Development | 普通株式 | 売却 | 500 | $5.95 |
| 2004-05-24 | BLUFORD, PETER | VP, Corporate Development | 普通株式 | 売却 | 500 | $5.65 |
| 2004-05-18 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 7,500 | $6.18 |
| 2004-05-17 | LANPHIER, EDWARD O II | Director, Pres & Chief Ex Officer | 普通株式 | 売却 | 12,500 | $6.16 |
| 2004-05-17 | BLUFORD, PETER | VP, Corporate Development | 普通株式 | 売却 | 500 | $5.95 |
| 2004-05-10 | BLUFORD, PETER | VP, Corporate Development | 普通株式 | 売却 | 500 | $6.12 |
| 2004-05-03 | BLUFORD, PETER | VP, Corporate Development | 普通株式 | 売却 | 500 | $6.41 |
| 2004-04-26 | BLUFORD, PETER | VP, Corporate Development | 普通株式 | 売却 | 500 | $6.54 |
| 2004-04-22 | LANPHIER, EDWARD O II | Director, President and CEO | ストックオプション | 購入 | 100,000 | $ |
| 2004-04-19 | BLUFORD, PETER | VP, Corporate Development | 普通株式 | 売却 | 500 | $5.87 |
| 2004-04-12 | BLUFORD, PETER | V.P., Corporate Development | 普通株式 | 売却 | 500 | $6.18 |
| 2004-04-05 | BLUFORD, PETER | V.P., Corporate Development | 普通株式 | 売却 | 500 | $6.51 |
| 2004-04-02 | LANPHIER, EDWARD O II | Director, President and CEO | 普通株式 | 売却 | 14,000 | $6.22 |
| 2004-04-01 | LANPHIER, EDWARD O II | Director, President and CEO | 普通株式 | 売却 | 6,000 | $6.14 |
| 2004-03-29 | BLUFORD, PETER | V.P., Corporate Development | 普通株式 | 売却 | 500 | $5.67 |
| 2004-03-22 | BLUFORD, PETER | VP, Corporate Development | 普通株式 | 売却 | 500 | $5.71 |
| 2004-03-17 | LANPHIER, EDWARD O II | Director, President and CEO | 普通株式 | 売却 | 17,620 | $6.04 |
| 2004-03-16 | LANPHIER, EDWARD O II | Director, President and CEO | 普通株式 | 売却 | 2,380 | $6.13 |
| 2004-03-15 | BLUFORD, PETER | VP, Corporate Development | 普通株式 | 売却 | 500 | $6.21 |
| 2004-03-08 | BLUFORD, PETER | VP, Corporate Finance | 普通株式 | 売却 | 500 | $6.57 |
| 2004-03-01 | BLUFORD, PETER | VP, Corporate Development | 普通株式 | 売却 | 500 | $5.53 |
| 2004-02-23 | BLUFORD, PETER | VP, Corporate Development | 普通株式 | 売却 | 500 | $5.91 |
| 2004-02-17 | BLUFORD, PETER | VP, Corporate Development | 普通株式 | 売却 | 500 | $6.26 |
| 2004-02-11 | JACOBY, JON E M | Director | 普通株式 | 購入 | 10,500 | $0.00 |
| 2004-02-11 | JACOBY, JON E M | Director | 普通株式 | 売却 | 10,500 | $0.00 |
| 2004-02-09 | BLUFORD, PETER | VP, Corporate Development | 普通株式 | 売却 | 500 | $5.56 |
| 2004-01-16 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 20,000 | $7.51 |
| 2004-01-15 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 20,000 | $7.68 |
| 2004-01-14 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 20,000 | $7.94 |
| 2004-01-13 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 20,000 | $6.51 |
| 2004-01-12 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 20,000 | $6.28 |
| 2004-01-08 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 20,000 | $5.64 |
| 2004-01-07 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 20,000 | $5.50 |
| 2003-12-02 | BLUFORD, PETER | VP Corporate Development | ストックオプション | 購入 | 10,000 | $ |
| 2003-12-02 | ZANTE, GREG | Sr Dir., Finance and Admin | ストックオプション | 購入 | 20,000 | $ |
| 2003-12-02 | CASE, CASEY C | Vice President, Research | ストックオプション | 購入 | 20,000 | $ |
| 2003-10-21 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 16,000 | $5.00 |
| 2003-05-30 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 30,000 | $4.14 |
| 2003-05-28 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 30,000 | $3.76 |
| 2003-05-27 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 30,000 | $2.87 |
| 2002-12-02 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 20,000 | $4.79 |
| 2002-11-25 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 20,000 | $4.46 |
| 2002-11-18 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 20,000 | $4.45 |
| 2002-11-07 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 10,000 | $3.02 |
| 2002-11-06 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 10,000 | $3.03 |
| 2002-11-05 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 5,000 | $2.98 |
| 2002-10-23 | KOPP, LEROY C | 10% Owner | 普通株式 | 売却 | 5,000 | $1.82 |
| 2001-11-07 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 5,000 | $8.34 |
| 2001-11-06 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 1,100 | $8.77 |
| 2001-11-06 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 3,800 | $8.72 |
| 2001-11-06 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 100 | $8.76 |
| 2001-11-05 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 100 | $8.29 |
| 2001-11-05 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 800 | $8.06 |
| 2001-11-05 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 100 | $8.08 |
| 2001-11-05 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 100 | $8.05 |
| 2001-11-05 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 100 | $8.34 |
| 2001-11-05 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 100 | $8.32 |
| 2001-11-05 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 100 | $8.19 |
| 2001-11-05 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 1,700 | $8.42 |
| 2001-11-05 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 100 | $8.37 |
| 2001-11-05 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 100 | $8.35 |
| 2001-11-05 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 1,100 | $8.09 |
| 2001-11-05 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 500 | $8.10 |
| 2001-11-05 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 100 | $8.12 |
| 2001-08-31 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 10,000 | $10.11 |
| 2001-07-19 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 5,000 | $15.01 |
| 2001-07-18 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 5,000 | $14.97 |
| 2001-06-29 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 10,000 | $14.14 |
| 2001-06-28 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 10,000 | $14.07 |
| 2001-01-26 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 10,000 | $23.46 |
| 2001-01-24 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 10,000 | $21.22 |
| 2000-10-23 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 7,000 | $31.18 |
| 2000-10-23 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 5,000 | $31.18 |
| 2000-09-15 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 5,000 | $43.77 |
| 2000-09-12 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 5,000 | $46.40 |
| 2000-08-25 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 5,000 | $43.60 |
| 2000-08-25 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 3,000 | $43.59 |
| 2000-08-24 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 5,000 | $39.77 |
| 2000-08-24 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 5,000 | $40.65 |
| 2000-08-22 | KOPP, LEROY C | 10% Owner | 普通株式 | 購入 | 5,000 | $38.96 |
売上・収益性
売上高（直近12ヶ月）
$3,955万ドル
一株あたり売上高（直近12ヶ月）
$0.14
売上総利益（直近12ヶ月）
$-7,312万ドル
営業利益（EBITDA：減価償却前）
$-10,405万ドル
利益率
0.0%
営業利益率（直近12ヶ月）
-175.5%
配当・収入
配当金額（1株あたり）
$None
配当利回り
0%
支払日
None
権利落ち日
None
バリュエーション指標
株価収益率（PER）
None倍
実績PER
-倍
予想PER
0.395倍
株価収益成長率（PEG）
0
株価売上高倍率（直近12ヶ月）
1.414倍
株価純資産倍率 (PBR)
18.13倍
1株当たり純資産（BPS）
-$0.04
企業価値倍率（EV）
EV/売上高倍率
1.401倍
EV/EBITDA倍率
-0.996倍
投資リターン
総資産利益率（直近12ヶ月）
-83.7%
自己資本利益率（直近12ヶ月）
-2892.0%
リターン分析
| 日数 | リターンレンジ | リターン中央値 | 累積リターン | 分散（バリアンス） | 標準偏差 | 最大下落率 | 最大下落期間 | SPYとの相関係数 | ||
|---|---|---|---|---|---|---|---|---|---|---|
| 15日間 | -33.9303% | 10.4682% | -2.963% | -56.6703% | 0.014736265230072071 | 0.1213930196925345 | -43.2381% | 3日 | -0.14129700277278665 | |
| 30日間 | -33.9303% | 15.3787% | -0.8356% | -45.322% | 0.011961550335296887 | 0.1093688727897334 | -43.2381% | 3日 | -0.03561150188114946 | |
| 90日間 | -33.9303% | 20.628% | -1.1245% | -74.7899% | 0.008143763208689026 | 0.09024280142309982 | -43.2381% | 3日 | -0.009342157442566048 |
損益計算書
会計期末日
2025-12-31
報告通貨
USD
売上高・粗利益
売上原価
営業経費
営業利益・税引前指標
売上高
$39,552,000
粗利益
$31,950,000
売上コスト
$7,602,000
商品・サービス原価
$7,602,000
販売管理費
$34,886,000
研究開発
$112,670,000
運営コスト
$139,954,000
減価償却
$None
減価償却・償却費
$7,602,000
営業利益
-$108,004,000
営業利益EBIT
-$108,004,000
償却前営業利益EBITA
-$100,402,000
税引前利益
-$123,500,000
利息・投資・その他営業外項目
税金関連
当期純・包括利益
純投資収益
$None
純金利収入
$1,302,000
利息収入
$1,302,000
金利コスト
$None
利息・債務コスト
$None
非利息収益
$None
営業外収益（その他）
$None
法人税等
-$568,000
継続事業純利益
-$122,932,000
純利益
-$122,932,000
税引後包括利益
$None
貸借対照表
会計期末日
2025-12-31
報告通貨
USD
総資産
$59,745,000
現金及び現金同等物
$20,948,000
現金及び短期投資
$20,948,000
短期投資
$None
在庫資産
$None
流動売掛金（純額）
$10,513,000
その他流動資産
$4,369,000
流動資産合計
$35,830,000
有形固定資産
$None
減価償却累計額（PPE）
$None
無形資産
$None
無形資産（のれん除く）
$None
のれん（無形資産）
$None
投資
$None
長期投資
$None
その他固定資産
$None
固定資産合計
$23,915,000
総負債
$74,013,000
買掛金（短期）
$14,437,000
前受金
$None
流動債務
$None
短期借入金
$1,702,000
固定長期負債
$None
その他流動負債
$15,286,000
流動負債合計
$42,466,000
リース債務
$26,795,000
長期債務
$None
長期債務（流動外）
$None
短期・長期借入金合計
$26,795,000
その他固定負債
$580,000
固定負債合計
$31,547,000
純資産
-$14,268,000
自己株式（金庫株）
$None
利益剰余金
-$1,627,249,000
普通株式
$3,507,000
発行済株式数（普通株）
$280,193,000
キャッシュフロー計算書
会計期末日
2025-12-31
報告通貨
USD
損益計算・収益性
営業活動
投資活動
損益
$None
純利益
-$122,932,000
営業キャッシュフロー
-$97,208,000
営業活動による支払い
$None
営業活動によるキャッシュフロー
$None
営業活動に関連する負債の増減額
$None
営業活動に関連する資産の増減額
$None
売掛金の増減額
$None
在庫資産の増減額
$None
減価償却・減耗費・償却費
$7,602,000
投資活動によるキャッシュフロー
-$102,000
設備投資
$102,000
財務活動
資金・為替照合
財務活動によるキャッシュフロー
$70,749,000
短期融資回収金
$None
自社株買い支出（普通株）
$None
自社株買い支出（優先株）
$None
自社株買い支出
$None
配当支払い（普通株）
$None
配当支払い（優先株）
$None
配当支払い
$None
資金調達（普通株）
$None
資金調達（優先株）
$None
資金調達（長期債・資本証券）
$None
自社株売却による収益
$None
自社株再取得による収益
$344,000
現金及び現金同等物の増減額
$None
為替レートの変動による増減額
$None
発行済株式数
広告パネル
スポンサー紹介
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