BMRN
バイオマリン・ファーマシューティカル
Biomarin Pharmaceutical Inc
株価・概要
$54.10
-1.17 (-2.1169%)
06:00AM 2026/04/17 (JST)
NASDAQ | USD
52週間レンジ
50.76
66.28
昨夜レンジ
53.79
55.62
前日終値
$55.27
出来高（数量）
1,459,410
ベータ値
0.291
50日移動平均値
$58.31
200日移動平均値
$56.56
1株あたりの利益（EPS）
1.8
予想PER（株価収益率）
11.14
配当金
$None
配当利回り
0%
インサイダー保有率
0.437%
機関投資家保有率
101.251%
BMRN - 会社概要
バイオマリン・ファーマシューティカル社は、希少な遺伝性疾患や重篤な医療状態を対象とした革新的な治療法の開発と商業化において先駆的な存在であり、バイオテクノロジー分野で確固たる地位を築いています。本社はカリフォルニア州サンラファエルにあり、同社は先進的な科学と技術を活用して、重要な未充足医療ニーズに対応する標的治療を創出しています。承認済み治療薬の強力なポートフォリオと研究開発への専念により、バイオマリンは持続的な成長が期待されており、希少疾患に苦しむ患者の生活向上に貢献することを使命としています。
本社住所
770 LINDARO STREET, SAN RAFAEL, CA, UNITED STATES, 94901
企業サイト
https://www.biomarin.com
会計年度終了
December
最新四半期
2025-12-31
利益・成長性
1株あたりの利益（EPS）
$1.80
希薄化後1株当たり利益EPS（直近12ヶ月）
$1.80
四半期利益成長率（前年比）
124.3%
四半期売上成長率（前年比）
17.0%
アナリスト予想・評価
目標株価
$88.87
強気
4
買い
14
ホールド
5
売り
0
弱気
0
EPS（1株当たり純利益）
| 7日前 | 30日前 | 60日前 | 90日前 | 予想レンジ | |||
|---|---|---|---|---|---|---|---|
配当履歴
| 権利落ち日 | 配当宣言日 | 権利確定日 | 配当金支払日 | 配当金額 |
|---|
株式分割
| 効力発生日 | 分割比率 |
|---|
インサイダーの売却・購入履歴
| 自社株取引日 | 役員・従業員名 | 役員・従業員の役職 | 株式の種類 | 売却／購入 | 株数 | 株価 |
|---|---|---|---|---|---|---|
| 2026-03-18 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 売却 | 1,273 | $56.05 |
| 2026-03-17 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 売却 | 1,693 | $56.05 |
| 2026-03-17 | FRIBERG, GREGORY R | EVP, Chief R&D Officer | 普通株式 | 売却 | 1,629 | $56.05 |
| 2026-03-17 | HUBBARD, CRISTIN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 1,245 | $56.05 |
| 2026-03-17 | HARDY, ALEXANDER | Director, Chief Executive Officer | 普通株式 | 売却 | 4,252 | $56.05 |
| 2026-03-17 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 2,117 | $56.05 |
| 2026-03-16 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 購入 | 14,990 | $0.00 |
| 2026-03-16 | HUBBARD, CRISTIN | EVP, Chief Commercial Officer | 普通株式 | 購入 | 15,410 | $0.00 |
| 2026-03-16 | FRIBERG, GREGORY R | EVP, Chief R&D Officer | 普通株式 | 購入 | 19,150 | $0.00 |
| 2026-03-16 | HUBBARD, CRISTIN | EVP, Chief Commercial Officer | 普通株式 | 購入 | 36,680 | $0.00 |
| 2026-03-16 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 購入 | 34,690 | $0.00 |
| 2026-03-16 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 売却 | 7,177 | $58.51 |
| 2026-03-16 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 購入 | 35,680 | $0.00 |
| 2026-03-16 | FRIBERG, GREGORY R | EVP, Chief R&D Officer | 普通株式 | 購入 | 45,600 | $0.00 |
| 2026-03-16 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 18,740 | $0.00 |
| 2026-03-16 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 44,600 | $0.00 |
| 2026-03-16 | HARDY, ALEXANDER | Director, Chief Executive Officer | 普通株式 | 購入 | 62,440 | $0.00 |
| 2026-03-16 | HARDY, ALEXANDER | Director, Chief Executive Officer | 普通株式 | 購入 | 89,200 | $0.00 |
| 2026-03-16 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 購入 | 14,570 | $0.00 |
| 2026-03-13 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 売却 | 9,109 | $58.51 |
| 2026-03-13 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 9,945 | $58.51 |
| 2026-03-13 | HARDY, ALEXANDER | Director, Chief Executive Officer | 普通株式 | 売却 | 2,941 | $58.51 |
| 2026-03-11 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 売却 | 16,486 | $60.46 |
| 2026-02-26 | FRIBERG, GREGORY R | EVP, Chief R&D Officer | 普通株式 | 売却 | 6,326 | $60.38 |
| 2026-02-26 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 売却 | 26,061 | $61.36 |
| 2026-02-25 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 購入 | 6,675 | $0.00 |
| 2026-02-25 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 2,569 | $0.00 |
| 2026-02-25 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 7,230 | $0.00 |
| 2026-02-25 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 6,683 | $0.00 |
| 2026-02-25 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 購入 | 2,372 | $0.00 |
| 2026-02-25 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 購入 | 6,675 | $0.00 |
| 2026-02-25 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 購入 | 6,177 | $0.00 |
| 2026-02-25 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 購入 | 2,371 | $0.00 |
| 2026-02-25 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 購入 | 6,176 | $0.00 |
| 2026-01-20 | RAMCHANDANI, RASHMI VIRENDRA | VP, Chief Accounting Officer | 普通株式 | 購入 | 18,220 | $0.00 |
| 2026-01-20 | RAMCHANDANI, RASHMI VIRENDRA | VP, Chief Accounting Officer | 普通株式 | 購入 | 7,070 | $0.00 |
| 2026-01-20 | RAMCHANDANI, RASHMI VIRENDRA | VP, Chief Accounting Officer | 普通株式 | 購入 | 18,540 | $0.00 |
| 2025-12-01 | HARDY, ALEXANDER | Director, Chief Executive Officer | 普通株式 | 売却 | 16,570 | $55.03 |
| 2025-09-30 | FRIBERG, GREGORY R | EVP, Chief R&D Officer | 普通株式 | 売却 | 3,304 | $54.16 |
| 2025-08-01 | CLARK, IAN T | Director | 普通株式 | 購入 | 7,000 | $0.00 |
| 2025-05-20 | BODEM, BARBARA W. | Director | 普通株式 | 購入 | 6,650 | $0.00 |
| 2025-05-20 | BURKHART, ERIN | GVP, Chief Accounting Officer | 普通株式 | 売却 | 1,786 | $59.31 |
| 2025-05-20 | DERE, WILLARD H | Director | 普通株式 | 購入 | 6,650 | $0.00 |
| 2025-05-20 | COUNTOURIOTIS, ATHENA | Director | 普通株式 | 購入 | 6,650 | $0.00 |
| 2025-05-20 | ANDERSON, ELIZABETH M | Director | 普通株式 | 購入 | 6,650 | $0.00 |
| 2025-05-20 | HUBBARD, CRISTIN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 2,155 | $59.93 |
| 2025-05-20 | ENYEDY, MARK J | Director | 普通株式 | 購入 | 6,650 | $0.00 |
| 2025-05-20 | HO, MAYKIN | Director | 普通株式 | 購入 | 6,650 | $0.00 |
| 2025-05-20 | WALBERT, TIMOTHY P | Director | 普通株式 | 購入 | 6,650 | $0.00 |
| 2025-05-20 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 6,650 | $0.00 |
| 2025-05-20 | HOMBACH, ROBERT J. | Director | 普通株式 | 購入 | 6,650 | $0.00 |
| 2025-05-19 | BURKHART, ERIN | GVP, Chief Accounting Officer | 普通株式 | 売却 | 996 | $59.27 |
| 2025-05-02 | HUBBARD, CRISTIN | EVP, Chief Commercial Officer | 普通株式 | 売却 | 273 | $64.92 |
| 2025-04-30 | HUBBARD, CRISTIN | EVP, Chief Commercial Officer | 普通株式 | 購入 | 273 | $54.14 |
| 2025-04-30 | HARDY, ALEXANDER | Director, Chief Executive Officer | 普通株式 | 購入 | 375 | $54.14 |
| 2025-03-19 | BURKHART, ERIN | GVP, Chief Accounting Officer | 普通株式 | 売却 | 1,295 | $71.52 |
| 2025-03-17 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 購入 | 13,310 | $0.00 |
| 2025-03-17 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 16,640 | $0.00 |
| 2025-03-17 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 38,590 | $0.00 |
| 2025-03-17 | HARDY, ALEXANDER | Director, Chief Executive Officer | 普通株式 | 購入 | 44,360 | $0.00 |
| 2025-03-17 | HARDY, ALEXANDER | Director, Chief Executive Officer | 普通株式 | 購入 | 61,750 | $0.00 |
| 2025-03-17 | FRIBERG, GREGORY R | EVP, Chief R&D Officer | 普通株式 | 購入 | 41,170 | $0.00 |
| 2025-03-17 | FRIBERG, GREGORY R | EVP, Chief R&D Officer | 普通株式 | 購入 | 17,750 | $0.00 |
| 2025-03-17 | HUBBARD, CRISTIN | EVP, Chief Commercial Officer | 普通株式 | 購入 | 30,880 | $0.00 |
| 2025-03-17 | HUBBARD, CRISTIN | EVP, Chief Commercial Officer | 普通株式 | 購入 | 13,310 | $0.00 |
| 2025-03-17 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 購入 | 30,020 | $0.00 |
| 2025-03-17 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 購入 | 12,940 | $0.00 |
| 2025-03-17 | BURKHART, ERIN | GVP, Chief Accounting Officer | 普通株式 | 購入 | 5,970 | $0.00 |
| 2025-03-17 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 購入 | 30,880 | $0.00 |
| 2025-03-17 | BURKHART, ERIN | GVP, Chief Accounting Officer | 普通株式 | 購入 | 9,230 | $0.00 |
| 2025-03-14 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 18,497 | $69.44 |
| 2025-03-14 | BURKHART, ERIN | GVP, Chief Accounting Officer | 普通株式 | 売却 | 823 | $69.44 |
| 2025-03-14 | HARDY, ALEXANDER | Director, Chief Executive Officer | 普通株式 | 売却 | 2,933 | $69.44 |
| 2025-03-14 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 売却 | 20,127 | $69.44 |
| 2025-03-14 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 売却 | 16,249 | $69.44 |
| 2025-03-06 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 売却 | 7,034 | $71.28 |
| 2025-02-28 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 売却 | 4,287 | $71.16 |
| 2025-02-25 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 購入 | 9,660 | $0.00 |
| 2025-02-25 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 購入 | 11,040 | $0.00 |
| 2025-02-25 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 購入 | 9,367 | $0.00 |
| 2025-02-25 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 購入 | 9,660 | $0.00 |
| 2025-02-25 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 購入 | 11,040 | $0.00 |
| 2025-02-25 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 9,367 | $0.00 |
| 2025-02-25 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 9,660 | $0.00 |
| 2025-02-25 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 11,040 | $0.00 |
| 2025-02-25 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 購入 | 9,367 | $0.00 |
| 2025-02-24 | BURKHART, ERIN | GVP, Chief Accounting Officer | 普通株式 | 売却 | 1,344 | $68.38 |
| 2025-02-24 | WALBERT, TIMOTHY P | Director | 普通株式 | 購入 | 3,130 | $0.00 |
| 2024-11-29 | HARDY, ALEXANDER | Director, Chief Executive Officer | 普通株式 | 売却 | 14,295 | $66.03 |
| 2024-11-12 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 売却 | 5,278 | $66.37 |
| 2024-10-31 | HARDY, ALEXANDER | Director, Chief Executive Officer | 普通株式 | 購入 | 300 | $56.01 |
| 2024-10-31 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 購入 | 55 | $56.01 |
| 2024-09-30 | FRIBERG, GREGORY R | EVP, Chief R&D Officer | 普通株式 | 購入 | 49,850 | $0.00 |
| 2024-09-30 | FRIBERG, GREGORY R | EVP, Chief R&D Officer | 普通株式 | 購入 | 21,190 | $0.00 |
| 2024-09-30 | FRIBERG, GREGORY R | EVP, Chief R&D Officer | 普通株式 | 購入 | 7,870 | $0.00 |
| 2024-09-13 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 12,098 | $84.90 |
| 2024-08-13 | BURKHART, ERIN | GVP, Chief Accounting Officer | 普通株式 | 売却 | 714 | $90.00 |
| 2024-06-28 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 588 | $82.33 |
| 2024-06-03 | HERON, ELAINE J | Director | 普通株式 | 購入 | 5,047 | $63.10 |
| 2024-06-03 | HERON, ELAINE J | Director | 普通株式 | 売却 | 4,168 | $76.41 |
| 2024-06-03 | HERON, ELAINE J | Director | 普通株式 | 売却 | 5,047 | $0.00 |
| 2024-06-03 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 6,600 | $63.10 |
| 2024-06-03 | MEIER, RICHARD A | Director | 普通株式 | 売却 | 5,451 | $76.41 |
| 2024-06-03 | MEIER, RICHARD A | Director | 普通株式 | 売却 | 6,600 | $0.00 |
| 2024-05-30 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 5,000 | $63.10 |
| 2024-05-30 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 5,000 | $75.19 |
| 2024-05-30 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2024-05-28 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 売却 | 40,850 | $0.00 |
| 2024-05-28 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 売却 | 38,071 | $74.46 |
| 2024-05-28 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 購入 | 40,850 | $63.10 |
| 2024-05-28 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 売却 | 2,779 | $75.29 |
| 2024-05-21 | HO, MAYKIN | Director | 普通株式 | 購入 | 4,720 | $0.00 |
| 2024-05-21 | COUNTOURIOTIS, ATHENA | Director | 普通株式 | 購入 | 4,720 | $0.00 |
| 2024-05-21 | BODEM, BARBARA W. | Director | 普通株式 | 購入 | 4,720 | $0.00 |
| 2024-05-21 | ANDERSON, ELIZABETH M | Director | 普通株式 | 購入 | 4,720 | $0.00 |
| 2024-05-21 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 7,080 | $0.00 |
| 2024-05-21 | PYOTT, DAVID E I | Director | 普通株式 | 購入 | 4,720 | $0.00 |
| 2024-05-21 | DERE, WILLARD H | Director | 普通株式 | 購入 | 4,720 | $0.00 |
| 2024-05-21 | ENYEDY, MARK J | Director | 普通株式 | 購入 | 4,720 | $0.00 |
| 2024-05-21 | HERON, ELAINE J | Director | 普通株式 | 購入 | 4,720 | $0.00 |
| 2024-05-21 | HOMBACH, ROBERT J. | Director | 普通株式 | 購入 | 4,720 | $0.00 |
| 2024-05-20 | HUBBARD, CRISTIN | EVP, Chief Commercial Officer | 普通株式 | 購入 | 14,690 | $0.00 |
| 2024-05-20 | HUBBARD, CRISTIN | EVP, Chief Commercial Officer | 普通株式 | 購入 | 4,700 | $0.00 |
| 2024-05-20 | HUBBARD, CRISTIN | EVP, Chief Commercial Officer | 普通株式 | 購入 | 33,520 | $0.00 |
| 2024-05-20 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 売却 | 1,202 | $77.05 |
| 2024-05-17 | BURKHART, ERIN | GVP, Chief Accounting Officer | 普通株式 | 売却 | 993 | $76.97 |
| 2024-05-10 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 売却 | 20,000 | $81.14 |
| 2024-05-10 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 売却 | 20,000 | $0.00 |
| 2024-05-10 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 20,000 | $63.10 |
| 2024-05-09 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 20,000 | $63.10 |
| 2024-05-09 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 売却 | 20,000 | $0.00 |
| 2024-05-09 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 売却 | 20,000 | $81.62 |
| 2024-05-03 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 売却 | 4,440 | $82.44 |
| 2024-05-02 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 5,000 | $82.91 |
| 2024-05-02 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 購入 | 1,850 | $63.10 |
| 2024-05-02 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 売却 | 1,850 | $85.01 |
| 2024-05-02 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 売却 | 1,850 | $0.00 |
| 2024-04-30 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 購入 | 245 | $68.65 |
| 2024-04-30 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 300 | $68.65 |
| 2024-04-30 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 購入 | 301 | $68.65 |
| 2024-04-30 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 300 | $68.65 |
| 2024-04-30 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 300 | $68.65 |
| 2024-04-12 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 売却 | 20,000 | $91.26 |
| 2024-04-12 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 売却 | 20,000 | $0.00 |
| 2024-04-12 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 20,000 | $63.10 |
| 2024-04-11 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 20,000 | $63.10 |
| 2024-04-11 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 売却 | 20,000 | $0.00 |
| 2024-04-11 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 売却 | 20,000 | $90.99 |
| 2024-04-10 | BURKHART, ERIN | GVP, Chief Accounting Officer | 普通株式 | 売却 | 2,286 | $90.00 |
| 2024-03-28 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 売却 | 24,602 | $88.34 |
| 2024-03-18 | BURKHART, ERIN | GVP, Chief Accounting Officer | 普通株式 | 売却 | 372 | $83.87 |
| 2024-03-18 | SLAMON, DENNIS | Director | 普通株式 | 購入 | 10,000 | $79.70 |
| 2024-03-18 | SLAMON, DENNIS | Director | 普通株式 | 売却 | 10,000 | $0.00 |
| 2024-03-18 | SLAMON, DENNIS | Director | 普通株式 | 売却 | 9,510 | $83.81 |
| 2024-03-15 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 22,580 | $83.87 |
| 2024-03-15 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 売却 | 85,209 | $83.87 |
| 2024-03-15 | HARDY, ALEXANDER | Director, Chief Executive Officer | 普通株式 | 購入 | 44,050 | $0.00 |
| 2024-03-15 | HARDY, ALEXANDER | Director, Chief Executive Officer | 普通株式 | 購入 | 32,780 | $0.00 |
| 2024-03-15 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 40,860 | $0.00 |
| 2024-03-15 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 33,485 | $83.87 |
| 2024-03-15 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 18,240 | $0.00 |
| 2024-03-15 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 25,540 | $0.00 |
| 2024-03-15 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 20,789 | $83.87 |
| 2024-03-15 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 11,400 | $0.00 |
| 2024-03-15 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 購入 | 23,630 | $0.00 |
| 2024-03-15 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 売却 | 20,424 | $83.87 |
| 2024-03-15 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 購入 | 10,550 | $0.00 |
| 2024-03-15 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 購入 | 22,990 | $0.00 |
| 2024-03-15 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 売却 | 21,699 | $83.87 |
| 2024-03-15 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 購入 | 10,260 | $0.00 |
| 2024-03-15 | BURKHART, ERIN | GVP, Chief Accounting Officer | 普通株式 | 購入 | 7,050 | $0.00 |
| 2024-03-15 | BURKHART, ERIN | GVP, Chief Accounting Officer | 普通株式 | 購入 | 4,720 | $0.00 |
| 2024-03-06 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 売却 | 1,000 | $86.71 |
| 2024-03-05 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 35,341 | $85.18 |
| 2024-03-05 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 売却 | 1,000 | $85.51 |
| 2024-03-05 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 4,000 | $87.07 |
| 2024-02-27 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 購入 | 9,063 | $0.00 |
| 2024-02-27 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 82,700 | $0.00 |
| 2024-02-27 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 9,238 | $0.00 |
| 2024-02-27 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 購入 | 20,840 | $0.00 |
| 2024-02-27 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 6,103 | $0.00 |
| 2024-02-27 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 8,802 | $0.00 |
| 2024-02-27 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 売却 | 1,000 | $90.35 |
| 2024-02-27 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 24,926 | $0.00 |
| 2024-02-27 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 35,975 | $0.00 |
| 2024-02-27 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 13,326 | $0.00 |
| 2024-02-27 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 30,640 | $0.00 |
| 2024-02-27 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 6,465 | $0.00 |
| 2024-02-27 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 9,338 | $0.00 |
| 2024-02-27 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 21,440 | $0.00 |
| 2024-02-27 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 購入 | 6,284 | $0.00 |
| 2024-02-27 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 購入 | 9,063 | $0.00 |
| 2024-02-27 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 購入 | 20,840 | $0.00 |
| 2024-02-27 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 購入 | 6,284 | $0.00 |
| 2024-02-27 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 20,220 | $0.00 |
| 2024-02-09 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 15,000 | $63.10 |
| 2024-02-09 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 売却 | 15,000 | $0.00 |
| 2024-02-09 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 売却 | 15,000 | $88.28 |
| 2024-02-08 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 売却 | 15,000 | $0.00 |
| 2024-02-08 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 15,000 | $63.10 |
| 2024-02-08 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 売却 | 15,000 | $89.77 |
| 2024-01-18 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 40 | $92.60 |
| 2024-01-10 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 売却 | 10,000 | $0.00 |
| 2024-01-10 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 売却 | 10,000 | $96.38 |
| 2024-01-10 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 10,000 | $63.10 |
| 2024-01-09 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 売却 | 10,000 | $0.00 |
| 2024-01-09 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 10,000 | $63.10 |
| 2024-01-09 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 売却 | 10,000 | $98.19 |
| 2024-01-08 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 50 | $99.05 |
| 2024-01-08 | MEIER, RICHARD A | Director | 普通株式 | 売却 | 3,000 | $0.00 |
| 2023-12-27 | BODEM, BARBARA W. | Director | 普通株式 | 購入 | 2,180 | $0.00 |
| 2023-12-27 | COUNTOURIOTIS, ATHENA | Director | 普通株式 | 購入 | 2,180 | $0.00 |
| 2023-12-27 | ENYEDY, MARK J | Director | 普通株式 | 購入 | 2,180 | $0.00 |
| 2023-12-21 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 売却 | 10,000 | $93.99 |
| 2023-12-21 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 10,000 | $63.10 |
| 2023-12-21 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 売却 | 10,000 | $0.00 |
| 2023-12-13 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 売却 | 13,764 | $95.30 |
| 2023-12-01 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 17,750 | $0.00 |
| 2023-12-01 | HARDY, ALEXANDER | Director, Chief Executive Officer | 普通株式 | 購入 | 150,529 | $0.00 |
| 2023-12-01 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 2,370 | $0.00 |
| 2023-12-01 | HARDY, ALEXANDER | Director, Chief Executive Officer | 普通株式 | 購入 | 68,039 | $0.00 |
| 2023-12-01 | HARDY, ALEXANDER | Director, Chief Executive Officer | 普通株式 | 購入 | 47,332 | $0.00 |
| 2023-12-01 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 購入 | 11,840 | $0.00 |
| 2023-10-31 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 購入 | 133 | $69.23 |
| 2023-10-04 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 10 | $85.57 |
| 2023-08-16 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 5,000 | $90.00 |
| 2023-08-10 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 12,000 | $90.43 |
| 2023-08-09 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 売却 | 5,360 | $93.30 |
| 2023-08-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 6,000 | $88.29 |
| 2023-08-08 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 売却 | 11,000 | $89.42 |
| 2023-08-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $88.10 |
| 2023-06-29 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 4,602 | $88.93 |
| 2023-06-29 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 576 | $88.93 |
| 2023-05-23 | HOMBACH, ROBERT J. | Director | 普通株式 | 購入 | 4,190 | $0.00 |
| 2023-05-23 | SLAMON, DENNIS | Director | 普通株式 | 購入 | 4,190 | $0.00 |
| 2023-05-23 | PYOTT, DAVID E I | Director | 普通株式 | 購入 | 4,190 | $0.00 |
| 2023-05-23 | ALLES, MARK J | Director | 普通株式 | 購入 | 4,190 | $0.00 |
| 2023-05-23 | ANDERSON, ELIZABETH M | Director | 普通株式 | 購入 | 4,190 | $0.00 |
| 2023-05-23 | DERE, WILLARD H | Director | 普通株式 | 購入 | 4,190 | $0.00 |
| 2023-05-23 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 4,190 | $0.00 |
| 2023-05-23 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 4,190 | $0.00 |
| 2023-05-23 | HERON, ELAINE J | Director | 普通株式 | 購入 | 4,190 | $0.00 |
| 2023-05-23 | HO, MAYKIN | Director | 普通株式 | 購入 | 4,190 | $0.00 |
| 2023-05-16 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 売却 | 210 | $0.00 |
| 2023-05-16 | BURKHART, ERIN | GVP, Chief Accounting Officer | 普通株式 | 売却 | 796 | $92.02 |
| 2023-05-12 | HERON, ELAINE J | Director | 普通株式 | 売却 | 8,500 | $0.00 |
| 2023-05-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 6,337 | $93.93 |
| 2023-05-12 | MEIER, RICHARD A | Director | 普通株式 | 売却 | 6,137 | $93.93 |
| 2023-05-12 | HERON, ELAINE J | Director | 普通株式 | 売却 | 6,137 | $93.93 |
| 2023-05-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 33,644 | $93.93 |
| 2023-05-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 7,370 | $0.00 |
| 2023-05-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 7,370 | $67.81 |
| 2023-05-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 39,130 | $67.81 |
| 2023-05-12 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 8,500 | $67.81 |
| 2023-05-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 39,130 | $0.00 |
| 2023-05-12 | HERON, ELAINE J | Director | 普通株式 | 購入 | 8,500 | $67.81 |
| 2023-05-12 | MEIER, RICHARD A | Director | 普通株式 | 売却 | 8,500 | $0.00 |
| 2023-05-11 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 30,000 | $0.00 |
| 2023-05-11 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,561 | $95.22 |
| 2023-05-11 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 24,439 | $94.55 |
| 2023-05-11 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 30,000 | $67.81 |
| 2023-05-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 21,453 | $94.65 |
| 2023-05-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 8,547 | $95.34 |
| 2023-05-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 30,000 | $67.81 |
| 2023-05-09 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 30,000 | $67.81 |
| 2023-05-09 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 13,626 | $94.22 |
| 2023-05-09 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,410 | $95.90 |
| 2023-05-09 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 14,964 | $95.49 |
| 2023-05-09 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 30,000 | $0.00 |
| 2023-05-04 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 売却 | 4,302 | $95.45 |
| 2023-04-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 317 | $66.88 |
| 2023-04-28 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 購入 | 317 | $66.88 |
| 2023-04-28 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 購入 | 239 | $66.88 |
| 2023-04-28 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 318 | $66.88 |
| 2023-04-28 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 317 | $66.88 |
| 2023-04-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $67.81 |
| 2023-04-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $0.00 |
| 2023-04-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $99.56 |
| 2023-04-06 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $67.81 |
| 2023-04-06 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $0.00 |
| 2023-04-06 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $96.13 |
| 2023-04-03 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 8,500 | $67.81 |
| 2023-04-03 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 8,500 | $97.09 |
| 2023-04-03 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 8,500 | $0.00 |
| 2023-03-16 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 36,000 | $93.41 |
| 2023-03-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 88,623 | $93.41 |
| 2023-03-16 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 20,510 | $93.41 |
| 2023-03-16 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 売却 | 19,957 | $93.41 |
| 2023-03-16 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 3,973 | $93.41 |
| 2023-03-15 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 購入 | 20,320 | $0.00 |
| 2023-03-15 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 2,708 | $87.74 |
| 2023-03-15 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 購入 | 20,320 | $0.00 |
| 2023-03-15 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 9,630 | $0.00 |
| 2023-03-15 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 売却 | 1,856 | $87.74 |
| 2023-03-15 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 購入 | 8,900 | $0.00 |
| 2023-03-15 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 23,070 | $0.00 |
| 2023-03-15 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 3,971 | $87.74 |
| 2023-03-15 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 10,110 | $0.00 |
| 2023-03-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 49,430 | $0.00 |
| 2023-03-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 9,437 | $87.74 |
| 2023-03-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 36,100 | $0.00 |
| 2023-03-15 | BURKHART, ERIN | GVP, Chief Accounting Officer | 普通株式 | 購入 | 5,720 | $0.00 |
| 2023-03-15 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 21,970 | $0.00 |
| 2023-03-15 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 16,840 | $0.00 |
| 2023-03-15 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 4,799 | $87.74 |
| 2023-03-15 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 38,450 | $0.00 |
| 2023-03-15 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 購入 | 8,900 | $0.00 |
| 2023-03-15 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 売却 | 3,025 | $87.74 |
| 2023-03-15 | BURKHART, ERIN | GVP, Chief Accounting Officer | 普通株式 | 購入 | 3,760 | $0.00 |
| 2023-03-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 8,000 | $0.00 |
| 2023-03-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 8,000 | $67.81 |
| 2023-03-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 8,000 | $90.45 |
| 2023-03-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 15,000 | $67.81 |
| 2023-03-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 15,000 | $0.00 |
| 2023-03-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 15,000 | $92.28 |
| 2023-02-28 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 購入 | 10,100 | $0.00 |
| 2023-02-28 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 12,660 | $0.00 |
| 2023-02-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 32,972 | $0.00 |
| 2023-02-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 44,860 | $0.00 |
| 2023-02-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 89,700 | $0.00 |
| 2023-02-28 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 13,392 | $0.00 |
| 2023-02-28 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 18,220 | $0.00 |
| 2023-02-28 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 7,629 | $0.00 |
| 2023-02-28 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 10,380 | $0.00 |
| 2023-02-28 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 20,760 | $0.00 |
| 2023-02-28 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 36,440 | $0.00 |
| 2023-02-28 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 1,250 | $0.00 |
| 2023-02-28 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 購入 | 7,424 | $0.00 |
| 2023-02-28 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 10,980 | $0.00 |
| 2023-02-28 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 購入 | 20,200 | $0.00 |
| 2023-02-24 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 購入 | 1,474 | $67.81 |
| 2023-02-24 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 売却 | 1,474 | $0.00 |
| 2023-02-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 6,000 | $109.15 |
| 2023-02-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 6,000 | $67.81 |
| 2023-02-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 15,000 | $110.11 |
| 2023-02-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 15,000 | $67.81 |
| 2023-02-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 6,000 | $0.00 |
| 2023-02-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 15,000 | $0.00 |
| 2023-02-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 200 | $0.00 |
| 2023-02-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 100 | $0.00 |
| 2023-01-25 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 49,000 | $67.81 |
| 2023-01-25 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 2,200 | $0.00 |
| 2023-01-25 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 4,175 | $116.15 |
| 2023-01-25 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 46,800 | $0.00 |
| 2023-01-25 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 44,825 | $115.65 |
| 2023-01-17 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $67.81 |
| 2023-01-17 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $111.55 |
| 2023-01-17 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $0.00 |
| 2023-01-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $112.25 |
| 2023-01-13 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 2,500 | $114.50 |
| 2023-01-13 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 2,500 | $0.00 |
| 2023-01-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $0.00 |
| 2023-01-13 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 2,500 | $63.10 |
| 2023-01-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $67.81 |
| 2022-12-13 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 2,500 | $107.50 |
| 2022-12-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $106.89 |
| 2022-12-13 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 2,500 | $63.10 |
| 2022-12-13 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 2,500 | $0.00 |
| 2022-12-02 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 1,101 | $104.50 |
| 2022-12-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 471 | $103.97 |
| 2022-12-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 260 | $103.98 |
| 2022-12-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 100 | $104.00 |
| 2022-12-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 69 | $104.06 |
| 2022-12-02 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 3,761 | $0.00 |
| 2022-12-02 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 2,139 | $0.00 |
| 2022-12-02 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 3,761 | $104.50 |
| 2022-12-02 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 3,761 | $67.81 |
| 2022-12-02 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 2,139 | $104.50 |
| 2022-12-02 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 2,139 | $67.81 |
| 2022-12-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 600 | $103.97 |
| 2022-11-23 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 3,500 | $0.00 |
| 2022-11-23 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 934 | $95.09 |
| 2022-11-23 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 945 | $99.50 |
| 2022-11-23 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 3,500 | $67.81 |
| 2022-11-23 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 3,500 | $99.50 |
| 2022-11-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 100 | $86.12 |
| 2022-11-02 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 3,000 | $86.12 |
| 2022-10-31 | ALLES, MARK J | Director | 普通株式 | 購入 | 3,625 | $86.75 |
| 2022-10-31 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,500 | $86.55 |
| 2022-10-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $89.89 |
| 2022-08-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $95.21 |
| 2022-08-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $94.75 |
| 2022-08-11 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 3,000 | $95.62 |
| 2022-08-09 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 売却 | 47,526 | $95.93 |
| 2022-08-09 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 売却 | 47,526 | $0.00 |
| 2022-08-09 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 売却 | 3,690 | $96.34 |
| 2022-08-09 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 購入 | 47,526 | $67.81 |
| 2022-08-08 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 売却 | 6,205 | $96.56 |
| 2022-08-05 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 3,500 | $67.81 |
| 2022-08-05 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 3,500 | $94.50 |
| 2022-08-05 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 3,500 | $0.00 |
| 2022-07-08 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 売却 | 7,398 | $90.00 |
| 2022-07-08 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 7,337 | $89.50 |
| 2022-06-29 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 576 | $83.92 |
| 2022-06-03 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 7,021 | $77.49 |
| 2022-05-26 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 1,308 | $78.94 |
| 2022-05-24 | HERON, ELAINE J | Director | 普通株式 | 購入 | 4,980 | $0.00 |
| 2022-05-24 | ALLES, MARK J | Director | 普通株式 | 購入 | 4,980 | $0.00 |
| 2022-05-24 | ANDERSON, ELIZABETH M | Director | 普通株式 | 購入 | 4,980 | $0.00 |
| 2022-05-24 | DERE, WILLARD H | Director | 普通株式 | 購入 | 4,980 | $0.00 |
| 2022-05-24 | HOMBACH, ROBERT J. | Director | 普通株式 | 購入 | 4,980 | $0.00 |
| 2022-05-24 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 4,980 | $0.00 |
| 2022-05-24 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 4,980 | $0.00 |
| 2022-05-24 | PYOTT, DAVID E I | Director | 普通株式 | 購入 | 4,980 | $0.00 |
| 2022-05-24 | SLAMON, DENNIS | Director | 普通株式 | 購入 | 4,980 | $0.00 |
| 2022-05-24 | HO, MAYKIN | Director | 普通株式 | 購入 | 4,980 | $0.00 |
| 2022-05-16 | BURKHART, ERIN | GVP, Chief Accounting Officer | 普通株式 | 購入 | 11,130 | $0.00 |
| 2022-05-16 | BURKHART, ERIN | GVP, Chief Accounting Officer | 普通株式 | 購入 | 17,490 | $0.00 |
| 2022-05-06 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 20,000 | $81.00 |
| 2022-05-06 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 20,000 | $0.00 |
| 2022-05-06 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 20,000 | $37.46 |
| 2022-05-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $37.46 |
| 2022-05-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $84.14 |
| 2022-05-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $0.00 |
| 2022-05-04 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 売却 | 3,926 | $84.65 |
| 2022-05-04 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 2,038 | $84.50 |
| 2022-05-04 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 9,762 | $84.50 |
| 2022-05-04 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 2,038 | $0.00 |
| 2022-05-04 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 9,762 | $0.00 |
| 2022-05-04 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 2,038 | $37.46 |
| 2022-05-04 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 9,762 | $37.46 |
| 2022-05-02 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 8,500 | $37.46 |
| 2022-05-02 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 売却 | 15,347 | $80.38 |
| 2022-05-02 | MEIER, RICHARD A | Director | 普通株式 | 売却 | 8,500 | $0.00 |
| 2022-05-02 | MEIER, RICHARD A | Director | 普通株式 | 売却 | 3,860 | $82.09 |
| 2022-05-02 | MEIER, RICHARD A | Director | 普通株式 | 売却 | 18 | $82.12 |
| 2022-05-02 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 売却 | 15,347 | $0.00 |
| 2022-05-02 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 購入 | 15,347 | $37.46 |
| 2022-04-29 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2022-04-29 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $81.95 |
| 2022-04-29 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $37.46 |
| 2022-04-29 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 341 | $62.41 |
| 2022-04-29 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 340 | $62.41 |
| 2022-04-29 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 購入 | 341 | $62.41 |
| 2022-04-29 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 340 | $62.41 |
| 2022-04-29 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 購入 | 243 | $62.41 |
| 2022-04-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 20,000 | $0.00 |
| 2022-04-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 20,000 | $37.46 |
| 2022-04-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 20,000 | $83.79 |
| 2022-04-25 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 売却 | 2,669 | $0.00 |
| 2022-04-25 | DAVIS, GEORGE ERIC | EVP, Chief Legal Officer | 普通株式 | 購入 | 2,669 | $37.46 |
| 2022-04-18 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 20,000 | $0.00 |
| 2022-04-18 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 20,000 | $37.46 |
| 2022-04-18 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 20,000 | $81.91 |
| 2022-04-14 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 4,250 | $83.66 |
| 2022-04-14 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 4,250 | $0.00 |
| 2022-04-14 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 4,250 | $37.46 |
| 2022-04-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $0.00 |
| 2022-04-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $83.66 |
| 2022-04-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $37.46 |
| 2022-04-13 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 1,180 | $82.47 |
| 2022-03-30 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 1,381 | $79.56 |
| 2022-03-29 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 1,618 | $79.43 |
| 2022-03-23 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 6,129 | $81.78 |
| 2022-03-22 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 2,073 | $81.00 |
| 2022-03-21 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 6,129 | $81.29 |
| 2022-03-16 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 582 | $80.72 |
| 2022-03-16 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 1,287 | $80.72 |
| 2022-03-16 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 1,252 | $80.72 |
| 2022-03-16 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 2,259 | $80.72 |
| 2022-03-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,560 | $80.72 |
| 2022-03-15 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 8,290 | $78.27 |
| 2022-03-15 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 26,520 | $0.00 |
| 2022-03-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 40,280 | $0.00 |
| 2022-03-15 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 11,940 | $0.00 |
| 2022-03-15 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 8,418 | $78.27 |
| 2022-03-15 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 28,670 | $0.00 |
| 2022-03-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 38,306 | $78.27 |
| 2022-03-15 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 購入 | 11,040 | $0.00 |
| 2022-03-15 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 35,830 | $0.00 |
| 2022-03-15 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 12,101 | $78.27 |
| 2022-03-15 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 38,790 | $0.00 |
| 2022-03-15 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 11,040 | $0.00 |
| 2022-03-15 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 1,868 | $78.27 |
| 2022-03-15 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 26,520 | $0.00 |
| 2022-03-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 58,040 | $0.00 |
| 2022-03-15 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 売却 | 920 | $78.27 |
| 2022-03-15 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 購入 | 26,520 | $0.00 |
| 2022-03-15 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 11,040 | $0.00 |
| 2022-03-11 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 15,000 | $77.81 |
| 2022-03-11 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 15,000 | $37.46 |
| 2022-03-11 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 15,000 | $0.00 |
| 2022-03-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 15,000 | $0.00 |
| 2022-03-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 15,000 | $37.46 |
| 2022-03-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 15,000 | $77.57 |
| 2022-03-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 34,780 | $0.00 |
| 2022-03-08 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 12,840 | $0.00 |
| 2022-03-08 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 9,370 | $0.00 |
| 2022-03-08 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 9,370 | $0.00 |
| 2022-02-28 | SLAMON, DENNIS | Director | 普通株式 | 売却 | 100 | $78.37 |
| 2022-02-28 | SLAMON, DENNIS | Director | 普通株式 | 売却 | 45 | $78.34 |
| 2022-02-28 | SLAMON, DENNIS | Director | 普通株式 | 売却 | 214 | $78.35 |
| 2022-02-28 | SLAMON, DENNIS | Director | 普通株式 | 売却 | 100 | $78.35 |
| 2022-02-28 | SLAMON, DENNIS | Director | 普通株式 | 売却 | 122 | $78.36 |
| 2022-02-28 | SLAMON, DENNIS | Director | 普通株式 | 売却 | 5,815 | $78.33 |
| 2022-02-25 | HERON, ELAINE J | Director | 普通株式 | 購入 | 8,500 | $37.46 |
| 2022-02-25 | HERON, ELAINE J | Director | 普通株式 | 売却 | 8,500 | $0.00 |
| 2022-02-03 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 1,072 | $87.77 |
| 2022-01-14 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 4,250 | $87.61 |
| 2022-01-14 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 4,250 | $37.46 |
| 2022-01-14 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 4,250 | $0.00 |
| 2022-01-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $37.46 |
| 2022-01-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2022-01-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $87.86 |
| 2022-01-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $89.00 |
| 2022-01-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $37.46 |
| 2022-01-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2022-01-03 | ALLES, MARK J | Director | 普通株式 | 購入 | 2,300 | $0.00 |
| 2021-12-21 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 100 | $89.22 |
| 2021-12-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 6,000 | $0.00 |
| 2021-12-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 6,000 | $84.68 |
| 2021-12-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 6,000 | $37.46 |
| 2021-12-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 6,000 | $0.00 |
| 2021-12-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 6,000 | $37.46 |
| 2021-12-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 6,000 | $82.71 |
| 2021-12-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 700 | $0.00 |
| 2021-12-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,500 | $87.22 |
| 2021-10-26 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 2,739 | $73.60 |
| 2021-10-20 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $37.46 |
| 2021-10-20 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $0.00 |
| 2021-09-09 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 50 | $78.77 |
| 2021-08-02 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 5,518 | $76.69 |
| 2021-07-16 | ACOSTA, ANDREA | GVP, Chief Accounting Officer | 普通株式 | 売却 | 285 | $78.84 |
| 2021-06-29 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 576 | $83.46 |
| 2021-06-21 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $37.46 |
| 2021-06-21 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $0.00 |
| 2021-05-25 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 5,120 | $0.00 |
| 2021-05-25 | HOMBACH, ROBERT J. | Director | 普通株式 | 購入 | 5,120 | $0.00 |
| 2021-05-25 | HERON, ELAINE J | Director | 普通株式 | 購入 | 5,120 | $0.00 |
| 2021-05-25 | SLAMON, DENNIS | Director | 普通株式 | 購入 | 5,120 | $0.00 |
| 2021-05-25 | PYOTT, DAVID E I | Director | 普通株式 | 購入 | 5,120 | $0.00 |
| 2021-05-25 | HO, MAYKIN | Director | 普通株式 | 購入 | 5,120 | $0.00 |
| 2021-05-25 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 5,120 | $0.00 |
| 2021-05-25 | DERE, WILLARD H | Director | 普通株式 | 購入 | 5,120 | $0.00 |
| 2021-05-25 | ANDERSON, ELIZABETH M | Director | 普通株式 | 購入 | 5,120 | $0.00 |
| 2021-05-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 8,513 | $26.49 |
| 2021-05-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 8,513 | $0.00 |
| 2021-05-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 8,513 | $77.29 |
| 2021-05-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 15,556 | $77.60 |
| 2021-05-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 25,000 | $0.00 |
| 2021-05-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,329 | $79.39 |
| 2021-05-07 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 6,709 | $0.00 |
| 2021-05-07 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 6,709 | $79.50 |
| 2021-05-07 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 6,709 | $28.23 |
| 2021-05-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 25,000 | $26.49 |
| 2021-05-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 6,115 | $78.77 |
| 2021-05-06 | MEIER, RICHARD A | Director | 普通株式 | 売却 | 15,000 | $0.00 |
| 2021-05-06 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,175 | $78.69 |
| 2021-05-06 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 14,825 | $78.01 |
| 2021-05-06 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 25,000 | $26.49 |
| 2021-05-06 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 25,000 | $0.00 |
| 2021-05-06 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 15,000 | $26.49 |
| 2021-05-06 | MEIER, RICHARD A | Director | 普通株式 | 売却 | 5,068 | $78.38 |
| 2021-05-04 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 売却 | 3,986 | $78.35 |
| 2021-05-03 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 2,089 | $78.30 |
| 2021-05-03 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 2,584 | $78.30 |
| 2021-04-30 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $37.46 |
| 2021-04-30 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $0.00 |
| 2021-04-30 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 341 | $62.41 |
| 2021-04-30 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 341 | $62.41 |
| 2021-04-30 | ACOSTA, ANDREA | GVP, Chief Accounting Officer | 普通株式 | 購入 | 271 | $62.41 |
| 2021-04-30 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 341 | $62.41 |
| 2021-04-30 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 342 | $62.41 |
| 2021-04-30 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 購入 | 221 | $62.41 |
| 2021-04-23 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $26.49 |
| 2021-04-23 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $79.34 |
| 2021-04-23 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $0.00 |
| 2021-04-22 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $26.49 |
| 2021-04-22 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $78.91 |
| 2021-04-22 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $0.00 |
| 2021-04-19 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 2,709 | $79.58 |
| 2021-04-19 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 2,709 | $0.00 |
| 2021-04-19 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 2,709 | $26.49 |
| 2021-04-15 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 7,500 | $76.90 |
| 2021-04-15 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 7,500 | $26.49 |
| 2021-04-15 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 7,500 | $0.00 |
| 2021-04-08 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 1,537 | $78.81 |
| 2021-04-01 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 5,692 | $76.30 |
| 2021-03-30 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 1,652 | $74.79 |
| 2021-03-24 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 1,181 | $76.30 |
| 2021-03-22 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 2,454 | $78.52 |
| 2021-03-22 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 516 | $78.52 |
| 2021-03-22 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 1,391 | $78.52 |
| 2021-03-22 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,519 | $78.52 |
| 2021-03-22 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 1,513 | $78.52 |
| 2021-03-18 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 1,308 | $77.99 |
| 2021-03-16 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 1,252 | $77.21 |
| 2021-03-16 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 2,259 | $77.21 |
| 2021-03-16 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 1,287 | $77.21 |
| 2021-03-16 | ACOSTA, ANDREA | GVP, Chief Accounting Officer | 普通株式 | 売却 | 379 | $77.21 |
| 2021-03-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,559 | $77.21 |
| 2021-03-16 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 582 | $77.21 |
| 2021-03-15 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 購入 | 10,420 | $0.00 |
| 2021-03-15 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 10,720 | $0.00 |
| 2021-03-15 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 5,273 | $78.39 |
| 2021-03-15 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 37,710 | $0.00 |
| 2021-03-15 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 10,420 | $0.00 |
| 2021-03-15 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 24,890 | $0.00 |
| 2021-03-15 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 994 | $78.39 |
| 2021-03-15 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 10,110 | $0.00 |
| 2021-03-15 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 購入 | 25,650 | $0.00 |
| 2021-03-15 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 7,460 | $78.39 |
| 2021-03-15 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 26,400 | $0.00 |
| 2021-03-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 41,350 | $0.00 |
| 2021-03-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 23,426 | $78.39 |
| 2021-03-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 101,820 | $0.00 |
| 2021-03-15 | ACOSTA, ANDREA | GVP, Chief Accounting Officer | 普通株式 | 購入 | 4,290 | $0.00 |
| 2021-03-15 | ACOSTA, ANDREA | GVP, Chief Accounting Officer | 普通株式 | 売却 | 553 | $78.39 |
| 2021-03-15 | ACOSTA, ANDREA | GVP, Chief Accounting Officer | 普通株式 | 購入 | 5,280 | $0.00 |
| 2021-03-15 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 15,320 | $0.00 |
| 2021-03-15 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 25,650 | $0.00 |
| 2021-03-15 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 5,014 | $78.39 |
| 2021-03-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 7,000 | $26.49 |
| 2021-03-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 7,000 | $77.10 |
| 2021-03-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 7,000 | $0.00 |
| 2021-03-11 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 7,000 | $26.49 |
| 2021-03-11 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 7,000 | $77.68 |
| 2021-03-11 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 7,000 | $0.00 |
| 2021-03-05 | GREY, MICHAEL G | Director | 普通株式 | 購入 | 5,000 | $26.49 |
| 2021-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 5,000 | $76.28 |
| 2021-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 5,000 | $0.00 |
| 2021-03-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 100 | $77.94 |
| 2021-02-19 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 7,000 | $0.00 |
| 2021-02-19 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 7,000 | $26.49 |
| 2021-02-19 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 7,000 | $83.58 |
| 2021-02-18 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 7,000 | $0.00 |
| 2021-02-18 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 7,000 | $85.08 |
| 2021-02-18 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 7,000 | $26.49 |
| 2021-02-17 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 8,000 | $84.54 |
| 2021-02-17 | HO, MAYKIN | Director | 普通株式 | 購入 | 2,350 | $0.00 |
| 2021-02-17 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 8,000 | $0.00 |
| 2021-02-17 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 8,000 | $26.49 |
| 2021-02-16 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 7,500 | $26.49 |
| 2021-02-16 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 7,500 | $87.41 |
| 2021-02-16 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 7,500 | $0.00 |
| 2021-02-03 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 売却 | 1,071 | $82.82 |
| 2021-01-29 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 8,334 | $0.00 |
| 2021-01-29 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 8,334 | $26.49 |
| 2021-01-29 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 8,334 | $82.67 |
| 2021-01-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 8,333 | $26.49 |
| 2021-01-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 8,333 | $82.91 |
| 2021-01-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 8,333 | $0.00 |
| 2021-01-27 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 8,333 | $85.49 |
| 2021-01-27 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 8,333 | $0.00 |
| 2021-01-27 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 8,333 | $26.49 |
| 2020-12-29 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,500 | $88.18 |
| 2020-12-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,500 | $88.77 |
| 2020-10-14 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 2,121 | $79.91 |
| 2020-10-07 | HERON, ELAINE J | Director | 普通株式 | 売却 | 15,000 | $0.00 |
| 2020-10-07 | HERON, ELAINE J | Director | 普通株式 | 購入 | 15,000 | $26.49 |
| 2020-08-31 | PYOTT, DAVID E I | Director | 普通株式 | 購入 | 900 | $78.84 |
| 2020-08-31 | PYOTT, DAVID E I | Director | 普通株式 | 購入 | 11,900 | $78.22 |
| 2020-08-03 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 2,500 | $0.00 |
| 2020-08-03 | GREY, MICHAEL G | Director | 普通株式 | 購入 | 2,500 | $26.49 |
| 2020-08-03 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 2,500 | $120.35 |
| 2020-07-20 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 49,423 | $63.10 |
| 2020-07-20 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 1,250 | $0.00 |
| 2020-07-20 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 75,716 | $0.00 |
| 2020-07-20 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 49,423 | $0.00 |
| 2020-07-20 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 126,389 | $130.00 |
| 2020-07-20 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 1,250 | $67.81 |
| 2020-07-20 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 75,716 | $67.81 |
| 2020-07-17 | ACOSTA, ANDREA | GVP, Chief Accouning Officer | 普通株式 | 売却 | 285 | $128.21 |
| 2020-07-13 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 13,810 | $67.81 |
| 2020-07-13 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 8,977 | $0.00 |
| 2020-07-13 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 13,810 | $0.00 |
| 2020-07-13 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 224 | $0.00 |
| 2020-07-13 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 23,011 | $130.00 |
| 2020-07-13 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 8,977 | $63.10 |
| 2020-07-13 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 224 | $67.81 |
| 2020-07-09 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 425 | $0.00 |
| 2020-06-29 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 4,640 | $0.00 |
| 2020-06-29 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 13,230 | $0.00 |
| 2020-06-26 | DERE, WILLARD H | Director | 普通株式 | 売却 | 4,430 | $123.61 |
| 2020-06-19 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 15,000 | $63.10 |
| 2020-06-19 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 15,000 | $124.00 |
| 2020-06-19 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 15,000 | $0.00 |
| 2020-06-05 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 4,430 | $107.46 |
| 2020-05-27 | HOMBACH, ROBERT J. | Director | 普通株式 | 購入 | 4,300 | $0.00 |
| 2020-05-27 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 4,300 | $0.00 |
| 2020-05-27 | SLAMON, DENNIS | Director | 普通株式 | 購入 | 4,300 | $0.00 |
| 2020-05-27 | PYOTT, DAVID E I | Director | 普通株式 | 購入 | 4,300 | $0.00 |
| 2020-05-27 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 4,300 | $0.00 |
| 2020-05-27 | ANDERSON, ELIZABETH M | Director | 普通株式 | 購入 | 4,300 | $0.00 |
| 2020-05-27 | GREY, MICHAEL G | Director | 普通株式 | 購入 | 4,300 | $0.00 |
| 2020-05-27 | DERE, WILLARD H | Director | 普通株式 | 購入 | 4,300 | $0.00 |
| 2020-05-27 | HERON, ELAINE J | Director | 普通株式 | 購入 | 4,300 | $0.00 |
| 2020-05-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 20,000 | $0.00 |
| 2020-05-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 20,000 | $21.51 |
| 2020-05-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 20,000 | $91.72 |
| 2020-05-04 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 購入 | 64,150 | $0.00 |
| 2020-05-04 | GUYER, CHARLES GREG | EVP, Chief Technical Officer | 普通株式 | 購入 | 35,040 | $0.00 |
| 2020-05-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $21.51 |
| 2020-05-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $88.00 |
| 2020-05-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2020-05-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 4,000 | $21.51 |
| 2020-05-01 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 12,504 | $89.38 |
| 2020-05-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $89.38 |
| 2020-05-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $0.00 |
| 2020-04-30 | MUELLER, BRIAN | EVP, Chief Financial Officer | 普通株式 | 購入 | 323 | $62.59 |
| 2020-04-30 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 338 | $62.59 |
| 2020-04-30 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 339 | $62.59 |
| 2020-04-30 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 339 | $62.59 |
| 2020-04-30 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 339 | $62.59 |
| 2020-04-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 20,000 | $21.51 |
| 2020-04-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 20,000 | $0.00 |
| 2020-04-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 20,000 | $97.58 |
| 2020-04-27 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 20,000 | $0.00 |
| 2020-04-27 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 20,000 | $21.51 |
| 2020-04-27 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 20,000 | $97.73 |
| 2020-04-24 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 13,642 | $95.34 |
| 2020-04-24 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 3,678 | $96.85 |
| 2020-04-24 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 2,680 | $97.32 |
| 2020-04-20 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 17,213 | $90.00 |
| 2020-04-09 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $79.06 |
| 2020-04-09 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $0.00 |
| 2020-04-09 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $21.51 |
| 2020-04-08 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 2,407 | $79.98 |
| 2020-04-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $26.49 |
| 2020-04-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $0.00 |
| 2020-04-01 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 1,537 | $82.00 |
| 2020-03-25 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 1,618 | $78.47 |
| 2020-03-24 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 2,041 | $74.36 |
| 2020-03-20 | BAFFI, ROBERT | President, Global Mfg/Tech Ops | 普通株式 | 売却 | 3,501 | $73.05 |
| 2020-03-20 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 3,599 | $73.05 |
| 2020-03-20 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 13,128 | $73.05 |
| 2020-03-20 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 5,836 | $73.05 |
| 2020-03-20 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 3,309 | $73.05 |
| 2020-03-20 | MUELLER, BRIAN | SVP, Acting CFO | 普通株式 | 売却 | 414 | $73.05 |
| 2020-03-17 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 3,750 | $75.39 |
| 2020-03-17 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 3,750 | $0.00 |
| 2020-03-17 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 3,750 | $21.51 |
| 2020-03-16 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 18,220 | $0.00 |
| 2020-03-16 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 4,610 | $76.52 |
| 2020-03-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 44,850 | $0.00 |
| 2020-03-16 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 10,100 | $0.00 |
| 2020-03-16 | MUELLER, BRIAN | SVP, Acting CFO | 普通株式 | 購入 | 9,600 | $0.00 |
| 2020-03-16 | MUELLER, BRIAN | SVP, Acting CFO | 普通株式 | 購入 | 6,730 | $0.00 |
| 2020-03-16 | BAFFI, ROBERT | President, Global Mfg/Tech Ops | 普通株式 | 購入 | 30,390 | $0.00 |
| 2020-03-16 | BAFFI, ROBERT | President, Global Mfg/Tech Ops | 普通株式 | 購入 | 10,660 | $0.00 |
| 2020-03-16 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 51,970 | $0.00 |
| 2020-03-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 127,920 | $0.00 |
| 2020-03-16 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 10,380 | $0.00 |
| 2020-03-16 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 29,590 | $0.00 |
| 2020-03-16 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 28,790 | $0.00 |
| 2020-03-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 30,952 | $84.50 |
| 2020-03-13 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 7,244 | $84.50 |
| 2020-03-13 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 10,496 | $84.50 |
| 2020-03-13 | BAFFI, ROBERT | President, Global Mfg/Tech Ops | 普通株式 | 売却 | 7,600 | $84.50 |
| 2020-03-13 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 7,644 | $84.50 |
| 2020-03-13 | MUELLER, BRIAN | SVP, Acting CFO | 普通株式 | 売却 | 1,303 | $84.50 |
| 2020-03-09 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $0.00 |
| 2020-03-09 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $89.52 |
| 2020-03-09 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $21.51 |
| 2020-03-03 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 9,586 | $0.00 |
| 2020-03-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 35,580 | $0.00 |
| 2020-03-03 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 13,136 | $0.00 |
| 2020-03-03 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 9,586 | $0.00 |
| 2020-03-03 | BAFFI, ROBERT | President, Global Mfg/Tech Ops | 普通株式 | 購入 | 9,852 | $0.00 |
| 2020-03-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 30 | $94.39 |
| 2020-02-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $21.51 |
| 2020-02-03 | MUELLER, BRIAN | SVP, Acting CFO | 普通株式 | 購入 | 5,800 | $0.00 |
| 2020-02-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $0.00 |
| 2020-02-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $83.50 |
| 2020-01-30 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $21.51 |
| 2020-01-30 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $0.00 |
| 2020-01-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 8,000 | $87.95 |
| 2020-01-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 8,000 | $0.00 |
| 2020-01-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 8,000 | $21.51 |
| 2020-01-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $84.92 |
| 2020-01-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 4,000 | $21.51 |
| 2020-01-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $0.00 |
| 2020-01-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $84.46 |
| 2020-01-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $0.00 |
| 2020-01-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 3,000 | $21.51 |
| 2019-12-27 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $21.51 |
| 2019-12-27 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2019-12-27 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $86.16 |
| 2019-12-26 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $86.43 |
| 2019-12-26 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $0.00 |
| 2019-12-26 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 3,000 | $21.51 |
| 2019-12-17 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 3,750 | $21.51 |
| 2019-12-17 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 3,750 | $83.36 |
| 2019-12-17 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 3,750 | $0.00 |
| 2019-12-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 630 | $0.00 |
| 2019-11-26 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 3,190 | $79.66 |
| 2019-11-22 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $77.60 |
| 2019-11-22 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $21.51 |
| 2019-11-22 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $0.00 |
| 2019-11-22 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 6,000 | $0.00 |
| 2019-11-11 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10 | $75.38 |
| 2019-11-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 450 | $0.00 |
| 2019-10-31 | MUELLER, BRIAN | SVP, Acting CFO | 普通株式 | 購入 | 9 | $62.23 |
| 2019-10-25 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $69.55 |
| 2019-10-25 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $21.51 |
| 2019-10-25 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2019-09-27 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $21.51 |
| 2019-09-27 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $0.00 |
| 2019-09-17 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 3,750 | $74.47 |
| 2019-09-17 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 3,750 | $0.00 |
| 2019-09-17 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 3,750 | $21.51 |
| 2019-08-07 | HERON, ELAINE J | Director | 普通株式 | 購入 | 1,553 | $63.10 |
| 2019-08-07 | HERON, ELAINE J | Director | 普通株式 | 売却 | 1,553 | $0.00 |
| 2019-07-09 | ANDERSON, ELIZABETH M | Director | 普通株式 | 購入 | 4,490 | $0.00 |
| 2019-06-17 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 3,750 | $21.51 |
| 2019-06-17 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 3,750 | $0.00 |
| 2019-06-17 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 3,750 | $81.08 |
| 2019-06-11 | MEIER, RICHARD A | Director | 普通株式 | 売却 | 6,000 | $0.00 |
| 2019-06-05 | BAFFI, ROBERT | President, Global Mfg/Tech Ops | 普通株式 | 購入 | 14,160 | $0.00 |
| 2019-06-05 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 300 | $0.00 |
| 2019-06-05 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 14,160 | $0.00 |
| 2019-06-04 | GREY, MICHAEL G | Director | 普通株式 | 購入 | 4,430 | $0.00 |
| 2019-06-04 | SLAMON, DENNIS | Director | 普通株式 | 購入 | 4,430 | $0.00 |
| 2019-06-04 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 4,430 | $0.00 |
| 2019-06-04 | HOMBACH, ROBERT J. | Director | 普通株式 | 購入 | 4,430 | $0.00 |
| 2019-06-04 | DERE, WILLARD H | Director | 普通株式 | 購入 | 4,430 | $0.00 |
| 2019-06-04 | HERON, ELAINE J | Director | 普通株式 | 購入 | 4,430 | $0.00 |
| 2019-06-04 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 4,430 | $0.00 |
| 2019-06-04 | PYOTT, DAVID E I | Director | 普通株式 | 購入 | 4,430 | $0.00 |
| 2019-06-04 | LEWIS, ALAN | Director | 普通株式 | 購入 | 4,430 | $0.00 |
| 2019-05-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $14.39 |
| 2019-05-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $82.52 |
| 2019-05-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $0.00 |
| 2019-05-09 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 4,000 | $14.39 |
| 2019-05-09 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $81.97 |
| 2019-05-09 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $0.00 |
| 2019-05-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $82.16 |
| 2019-05-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 4,000 | $14.39 |
| 2019-05-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $0.00 |
| 2019-04-30 | BAFFI, ROBERT | President, Global Mfg/Tech Ops | 普通株式 | 購入 | 309 | $68.78 |
| 2019-04-30 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 309 | $68.78 |
| 2019-04-30 | MUELLER, BRIAN | SVP, Finance and CAO | 普通株式 | 購入 | 299 | $68.78 |
| 2019-04-30 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 176 | $68.78 |
| 2019-04-30 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 309 | $68.78 |
| 2019-04-30 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 309 | $68.78 |
| 2019-04-30 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 309 | $68.78 |
| 2019-04-26 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 3,000 | $14.39 |
| 2019-04-26 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $0.00 |
| 2019-04-26 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 200 | $84.41 |
| 2019-04-26 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 800 | $83.59 |
| 2019-04-26 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $82.44 |
| 2019-04-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $0.00 |
| 2019-04-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $21.51 |
| 2019-04-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $0.00 |
| 2019-04-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $89.12 |
| 2019-04-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 4,000 | $14.39 |
| 2019-04-11 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $0.00 |
| 2019-04-11 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $14.39 |
| 2019-04-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,200 | $91.27 |
| 2019-04-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 100 | $92.39 |
| 2019-04-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 700 | $93.67 |
| 2019-04-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $0.00 |
| 2019-04-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 3,000 | $14.39 |
| 2019-04-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 3,000 | $14.39 |
| 2019-04-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $0.00 |
| 2019-04-05 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 売却 | 2,953 | $94.00 |
| 2019-04-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $93.37 |
| 2019-04-01 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 13,473 | $89.00 |
| 2019-03-27 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 2,150 | $89.76 |
| 2019-03-27 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 2,150 | $14.39 |
| 2019-03-27 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 2,150 | $0.00 |
| 2019-03-27 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 100 | $90.00 |
| 2019-03-27 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $14.39 |
| 2019-03-27 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $0.00 |
| 2019-03-26 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 3,656 | $89.18 |
| 2019-03-25 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 4,000 | $14.39 |
| 2019-03-25 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 5,932 | $87.86 |
| 2019-03-25 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 3,363 | $87.86 |
| 2019-03-25 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $0.00 |
| 2019-03-25 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $87.86 |
| 2019-03-22 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 13,127 | $88.05 |
| 2019-03-22 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 3,309 | $88.05 |
| 2019-03-22 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 3,598 | $88.05 |
| 2019-03-22 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 5,836 | $88.05 |
| 2019-03-22 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 3,598 | $88.05 |
| 2019-03-22 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 3,501 | $88.05 |
| 2019-03-22 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 売却 | 415 | $88.05 |
| 2019-03-21 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 2,589 | $89.62 |
| 2019-03-21 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 1,930 | $90.47 |
| 2019-03-19 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 7,907 | $93.92 |
| 2019-03-19 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $14.39 |
| 2019-03-19 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 3,728 | $93.07 |
| 2019-03-19 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $0.00 |
| 2019-03-18 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 9,597 | $94.09 |
| 2019-03-15 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 24,120 | $0.00 |
| 2019-03-15 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 7,169 | $94.53 |
| 2019-03-15 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 購入 | 5,780 | $0.00 |
| 2019-03-15 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 9,370 | $0.00 |
| 2019-03-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 28,143 | $94.53 |
| 2019-03-15 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 23,450 | $0.00 |
| 2019-03-15 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 9,370 | $0.00 |
| 2019-03-15 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 6,648 | $94.53 |
| 2019-03-15 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 売却 | 1,149 | $94.53 |
| 2019-03-15 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 購入 | 9,650 | $0.00 |
| 2019-03-15 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 9,443 | $94.53 |
| 2019-03-15 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 12,840 | $0.00 |
| 2019-03-15 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 32,160 | $0.00 |
| 2019-03-15 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 23,450 | $0.00 |
| 2019-03-15 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 9,370 | $0.00 |
| 2019-03-15 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 7,227 | $94.53 |
| 2019-03-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 34,780 | $0.00 |
| 2019-03-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 4,000 | $14.39 |
| 2019-03-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $94.40 |
| 2019-03-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 87,080 | $0.00 |
| 2019-03-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $0.00 |
| 2019-03-15 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 7,083 | $94.53 |
| 2019-03-15 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 9,630 | $0.00 |
| 2019-03-15 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 23,450 | $0.00 |
| 2019-03-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 3,000 | $14.39 |
| 2019-03-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $93.42 |
| 2019-03-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $0.00 |
| 2019-03-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $91.44 |
| 2019-03-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 4,000 | $14.39 |
| 2019-03-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $0.00 |
| 2019-03-11 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2019-03-11 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $88.96 |
| 2019-03-11 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $14.39 |
| 2019-03-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 4,000 | $14.39 |
| 2019-03-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $90.78 |
| 2019-03-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $0.00 |
| 2019-03-04 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 2,196 | $95.00 |
| 2019-03-01 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 12,205 | $0.00 |
| 2019-03-01 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 912 | $94.76 |
| 2019-03-01 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 917 | $94.76 |
| 2019-03-01 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 12,557 | $0.00 |
| 2019-03-01 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 840 | $94.76 |
| 2019-03-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,909 | $94.76 |
| 2019-03-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 45,320 | $0.00 |
| 2019-03-01 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 917 | $94.76 |
| 2019-03-01 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 11,853 | $0.00 |
| 2019-03-01 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 11,853 | $0.00 |
| 2019-03-01 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 1,154 | $94.76 |
| 2019-03-01 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 15,687 | $0.00 |
| 2019-02-27 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $91.78 |
| 2019-02-27 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 4,000 | $14.39 |
| 2019-02-27 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $0.00 |
| 2019-02-21 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $90.12 |
| 2019-02-21 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 3,000 | $14.39 |
| 2019-02-21 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $0.00 |
| 2019-02-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $0.00 |
| 2019-02-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $95.20 |
| 2019-02-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 4,000 | $14.39 |
| 2019-02-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $98.63 |
| 2019-02-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 4,000 | $14.39 |
| 2019-02-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $0.00 |
| 2019-01-22 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $96.82 |
| 2019-01-22 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $0.00 |
| 2019-01-22 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 3,000 | $14.39 |
| 2019-01-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $0.00 |
| 2019-01-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 4,000 | $14.39 |
| 2019-01-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $93.79 |
| 2019-01-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $0.00 |
| 2019-01-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $90.55 |
| 2019-01-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 3,000 | $14.39 |
| 2019-01-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 6,000 | $14.39 |
| 2019-01-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,599 | $91.55 |
| 2019-01-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,401 | $91.73 |
| 2019-01-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 6,000 | $0.00 |
| 2019-01-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $91.14 |
| 2019-01-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $0.00 |
| 2019-01-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 3,000 | $14.39 |
| 2019-01-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $87.58 |
| 2018-12-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $84.04 |
| 2018-12-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $0.00 |
| 2018-12-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 3,000 | $14.39 |
| 2018-12-27 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 2,150 | $0.00 |
| 2018-12-27 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 2,150 | $82.53 |
| 2018-12-27 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 2,150 | $14.39 |
| 2018-12-26 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 4,000 | $14.39 |
| 2018-12-26 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $0.00 |
| 2018-12-26 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $80.50 |
| 2018-12-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $0.00 |
| 2018-12-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 2,000 | $17.86 |
| 2018-12-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $92.64 |
| 2018-12-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $0.00 |
| 2018-12-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 2,000 | $17.86 |
| 2018-12-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $93.12 |
| 2018-11-20 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 540 | $0.00 |
| 2018-11-19 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 160 | $0.00 |
| 2018-11-14 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 2,400 | $92.21 |
| 2018-11-14 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 799 | $93.81 |
| 2018-11-14 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 600 | $94.35 |
| 2018-11-14 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 9,000 | $0.00 |
| 2018-11-14 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 5,201 | $91.62 |
| 2018-11-14 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 9,000 | $63.10 |
| 2018-11-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,500 | $17.86 |
| 2018-11-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,500 | $0.00 |
| 2018-11-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,500 | $97.88 |
| 2018-11-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $92.55 |
| 2018-11-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 4,000 | $14.39 |
| 2018-11-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $0.00 |
| 2018-10-31 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 購入 | 22 | $68.78 |
| 2018-10-31 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 175 | $68.78 |
| 2018-10-30 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $14.39 |
| 2018-10-30 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $0.00 |
| 2018-10-24 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $0.00 |
| 2018-10-24 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $14.39 |
| 2018-10-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,500 | $0.00 |
| 2018-10-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,500 | $99.36 |
| 2018-10-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,500 | $17.86 |
| 2018-10-03 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 1,000 | $98.98 |
| 2018-09-27 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 2,150 | $97.93 |
| 2018-09-27 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 2,150 | $14.39 |
| 2018-09-27 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 2,150 | $0.00 |
| 2018-09-25 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $14.39 |
| 2018-09-25 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $0.00 |
| 2018-09-14 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 200 | $99.46 |
| 2018-09-14 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 616 | $99.46 |
| 2018-09-14 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 1,400 | $99.45 |
| 2018-09-13 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 12,000 | $21.51 |
| 2018-09-13 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 12,000 | $99.57 |
| 2018-09-13 | MEIER, RICHARD A | Director | 普通株式 | 売却 | 12,000 | $0.00 |
| 2018-09-13 | MEIER, RICHARD A | Director | 普通株式 | 売却 | 3,000 | $0.00 |
| 2018-09-13 | MEIER, RICHARD A | Director | 普通株式 | 売却 | 200 | $99.25 |
| 2018-09-13 | MEIER, RICHARD A | Director | 普通株式 | 売却 | 2,800 | $99.24 |
| 2018-09-13 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 3,000 | $21.51 |
| 2018-09-05 | HERON, ELAINE J | Director | 普通株式 | 売却 | 1,000 | $96.94 |
| 2018-09-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,500 | $0.00 |
| 2018-09-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,500 | $98.16 |
| 2018-09-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,500 | $17.86 |
| 2018-08-28 | LEWIS, ALAN | Director | 普通株式 | 購入 | 7,500 | $14.39 |
| 2018-08-28 | LEWIS, ALAN | Director | 普通株式 | 売却 | 200 | $99.12 |
| 2018-08-28 | LEWIS, ALAN | Director | 普通株式 | 売却 | 7,500 | $0.00 |
| 2018-08-28 | LEWIS, ALAN | Director | 普通株式 | 売却 | 7,300 | $99.11 |
| 2018-08-27 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 2,000 | $14.39 |
| 2018-08-27 | MEIER, RICHARD A | Director | 普通株式 | 売却 | 2,000 | $100.12 |
| 2018-08-27 | MEIER, RICHARD A | Director | 普通株式 | 売却 | 2,000 | $0.00 |
| 2018-08-27 | MEIER, RICHARD A | Director | 普通株式 | 売却 | 13,000 | $0.00 |
| 2018-08-27 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 12,500 | $100.00 |
| 2018-08-27 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 13,000 | $14.39 |
| 2018-08-24 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 12,500 | $99.00 |
| 2018-08-21 | LEWIS, ALAN | Director | 普通株式 | 売却 | 4,200 | $100.09 |
| 2018-08-07 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 売却 | 2,500 | $104.50 |
| 2018-08-07 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 5,173 | $105.00 |
| 2018-08-07 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 売却 | 782 | $0.00 |
| 2018-08-07 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 購入 | 1,718 | $28.23 |
| 2018-08-07 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 売却 | 1,718 | $0.00 |
| 2018-08-07 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 購入 | 782 | $28.23 |
| 2018-07-23 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,500 | $101.69 |
| 2018-07-23 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,500 | $17.86 |
| 2018-07-23 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,500 | $0.00 |
| 2018-06-27 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 2,150 | $93.52 |
| 2018-06-27 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 2,150 | $0.00 |
| 2018-06-27 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 2,150 | $14.39 |
| 2018-06-22 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 9,528 | $99.00 |
| 2018-06-22 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 472 | $99.01 |
| 2018-06-22 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 6,949 | $14.39 |
| 2018-06-22 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 6,621 | $99.00 |
| 2018-06-22 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 328 | $99.01 |
| 2018-06-22 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 6,949 | $0.00 |
| 2018-06-22 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 売却 | 654 | $99.50 |
| 2018-06-22 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 購入 | 2,491 | $28.23 |
| 2018-06-22 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 売却 | 2,491 | $0.00 |
| 2018-06-22 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 売却 | 2,491 | $99.50 |
| 2018-06-15 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 売却 | 2,021 | $94.50 |
| 2018-06-14 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 2,000 | $0.00 |
| 2018-06-14 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 2,669 | $0.00 |
| 2018-06-14 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 2,000 | $90.00 |
| 2018-06-14 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 3,775 | $26.49 |
| 2018-06-14 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 20,681 | $90.00 |
| 2018-06-14 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 20,681 | $37.46 |
| 2018-06-14 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 1,875 | $90.00 |
| 2018-06-14 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 1,875 | $26.49 |
| 2018-06-14 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 2,669 | $90.00 |
| 2018-06-14 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 2,669 | $37.46 |
| 2018-06-14 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 3,775 | $90.00 |
| 2018-06-14 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 20,681 | $0.00 |
| 2018-06-14 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 1,875 | $0.00 |
| 2018-06-14 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 3,775 | $0.00 |
| 2018-06-14 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 2,000 | $21.51 |
| 2018-06-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $14.39 |
| 2018-06-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $0.00 |
| 2018-06-11 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 1,436 | $90.31 |
| 2018-06-05 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 4,300 | $0.00 |
| 2018-06-05 | HOMBACH, ROBERT J. | Director | 普通株式 | 購入 | 4,300 | $0.00 |
| 2018-06-05 | PYOTT, DAVID E I | Director | 普通株式 | 購入 | 4,300 | $0.00 |
| 2018-06-05 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 4,300 | $0.00 |
| 2018-06-05 | SLAMON, DENNIS | Director | 普通株式 | 購入 | 4,300 | $0.00 |
| 2018-06-05 | LEWIS, ALAN | Director | 普通株式 | 購入 | 4,300 | $0.00 |
| 2018-06-05 | HERON, ELAINE J | Director | 普通株式 | 購入 | 4,300 | $0.00 |
| 2018-06-05 | GREY, MICHAEL G | Director | 普通株式 | 購入 | 4,300 | $0.00 |
| 2018-06-05 | DERE, WILLARD H | Director | 普通株式 | 購入 | 4,300 | $0.00 |
| 2018-06-04 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 1,414 | $92.07 |
| 2018-06-04 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 1,934 | $92.07 |
| 2018-06-04 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 1,711 | $92.07 |
| 2018-06-04 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 売却 | 346 | $92.07 |
| 2018-06-04 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 1,414 | $92.07 |
| 2018-06-04 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 1,562 | $92.07 |
| 2018-06-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 6,310 | $92.07 |
| 2018-05-17 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 15,000 | $38.59 |
| 2018-05-17 | MEIER, RICHARD A | Director | 普通株式 | 売却 | 15,000 | $0.00 |
| 2018-05-17 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 18,750 | $38.59 |
| 2018-05-17 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 18,750 | $88.66 |
| 2018-05-17 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 18,750 | $0.00 |
| 2018-05-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 18,750 | $38.59 |
| 2018-05-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 18,750 | $89.13 |
| 2018-05-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 18,750 | $0.00 |
| 2018-05-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 18,750 | $0.00 |
| 2018-05-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 18,750 | $38.59 |
| 2018-05-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 18,750 | $88.29 |
| 2018-05-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 18,750 | $0.00 |
| 2018-05-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 18,750 | $89.22 |
| 2018-05-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 18,750 | $38.59 |
| 2018-05-11 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 18,750 | $88.42 |
| 2018-05-11 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 18,750 | $38.59 |
| 2018-05-11 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 18,750 | $0.00 |
| 2018-05-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 18,750 | $0.00 |
| 2018-05-10 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 売却 | 2,450 | $89.50 |
| 2018-05-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 18,750 | $89.59 |
| 2018-05-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 18,750 | $38.59 |
| 2018-05-07 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 309 | $85.96 |
| 2018-04-30 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 309 | $68.78 |
| 2018-04-30 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 購入 | 287 | $68.78 |
| 2018-04-30 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 309 | $68.78 |
| 2018-04-30 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 309 | $68.78 |
| 2018-04-30 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 167 | $68.78 |
| 2018-04-30 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 309 | $68.78 |
| 2018-04-30 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 309 | $68.78 |
| 2018-04-24 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $38.59 |
| 2018-04-24 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $0.00 |
| 2018-04-24 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $82.29 |
| 2018-04-23 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 11,059 | $82.15 |
| 2018-04-23 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $82.58 |
| 2018-04-23 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $38.59 |
| 2018-04-23 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $0.00 |
| 2018-04-20 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $83.65 |
| 2018-04-20 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $38.59 |
| 2018-04-20 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $0.00 |
| 2018-04-17 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 3,750 | $0.00 |
| 2018-04-17 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 3,750 | $85.00 |
| 2018-04-17 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 3,750 | $38.59 |
| 2018-04-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $14.39 |
| 2018-04-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $0.00 |
| 2018-04-02 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 6,650 | $37.46 |
| 2018-04-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $14.39 |
| 2018-04-02 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 2,119 | $80.12 |
| 2018-04-02 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 3,350 | $26.49 |
| 2018-04-02 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 3,350 | $80.12 |
| 2018-04-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $0.00 |
| 2018-04-02 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 6,650 | $80.12 |
| 2018-04-02 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 3,350 | $0.00 |
| 2018-04-02 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 6,650 | $0.00 |
| 2018-03-29 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 1,537 | $79.69 |
| 2018-03-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $17.86 |
| 2018-03-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $14.39 |
| 2018-03-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $0.00 |
| 2018-03-27 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $14.39 |
| 2018-03-27 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $0.00 |
| 2018-03-26 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $14.39 |
| 2018-03-26 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $0.00 |
| 2018-03-23 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 3,350 | $81.35 |
| 2018-03-22 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 3,500 | $81.36 |
| 2018-03-22 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 3,486 | $81.36 |
| 2018-03-22 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 3,295 | $81.36 |
| 2018-03-22 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 3,598 | $81.36 |
| 2018-03-22 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 5,835 | $81.36 |
| 2018-03-22 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 3,308 | $81.36 |
| 2018-03-22 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 3,583 | $81.36 |
| 2018-03-22 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 3,583 | $81.36 |
| 2018-03-22 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 売却 | 414 | $81.36 |
| 2018-03-22 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 13,127 | $81.36 |
| 2018-03-22 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 3,598 | $81.36 |
| 2018-03-22 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 5,812 | $81.36 |
| 2018-03-22 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $0.00 |
| 2018-03-22 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 13,075 | $81.36 |
| 2018-03-22 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $14.39 |
| 2018-03-21 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 4,368 | $83.90 |
| 2018-03-16 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 3,818 | $83.88 |
| 2018-03-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 15,000 | $38.59 |
| 2018-03-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 15,000 | $83.26 |
| 2018-03-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 15,000 | $0.00 |
| 2018-03-16 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 売却 | 346 | $84.10 |
| 2018-03-15 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 3,815 | $83.57 |
| 2018-03-15 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 購入 | 9,120 | $0.00 |
| 2018-03-15 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 購入 | 5,710 | $0.00 |
| 2018-03-15 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 41,040 | $0.00 |
| 2018-03-15 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 12,480 | $0.00 |
| 2018-03-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 15,000 | $38.59 |
| 2018-03-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 15,000 | $84.73 |
| 2018-03-15 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 39,900 | $0.00 |
| 2018-03-15 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 売却 | 309 | $83.57 |
| 2018-03-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 14,908 | $83.57 |
| 2018-03-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 46,340 | $0.00 |
| 2018-03-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 15,000 | $38.59 |
| 2018-03-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 148,190 | $0.00 |
| 2018-03-15 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 3,757 | $83.57 |
| 2018-03-15 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 12,120 | $0.00 |
| 2018-03-15 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 38,760 | $0.00 |
| 2018-03-15 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 4,861 | $83.57 |
| 2018-03-15 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 16,040 | $0.00 |
| 2018-03-15 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 51,300 | $0.00 |
| 2018-03-15 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 3,644 | $83.57 |
| 2018-03-15 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 12,120 | $0.00 |
| 2018-03-15 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 38,760 | $0.00 |
| 2018-03-15 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 3,651 | $83.57 |
| 2018-03-15 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 12,840 | $0.00 |
| 2018-03-09 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 2,972 | $82.39 |
| 2018-03-05 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 2,105 | $79.04 |
| 2018-03-02 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 1,615 | $79.86 |
| 2018-03-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $0.00 |
| 2018-03-02 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 1,609 | $79.86 |
| 2018-03-02 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 2,576 | $79.86 |
| 2018-03-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $14.39 |
| 2018-03-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 8,542 | $79.86 |
| 2018-03-02 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 2,071 | $79.86 |
| 2018-03-02 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 1,614 | $79.86 |
| 2018-02-26 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 12,529 | $0.00 |
| 2018-02-26 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 12,529 | $0.00 |
| 2018-02-26 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 45,722 | $0.00 |
| 2018-02-26 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 12,615 | $0.00 |
| 2018-02-26 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 46,034 | $0.00 |
| 2018-02-26 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 12,615 | $0.00 |
| 2018-02-26 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 11,523 | $0.00 |
| 2018-02-26 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 20,324 | $0.00 |
| 2018-02-26 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 11,601 | $0.00 |
| 2018-02-26 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 20,463 | $0.00 |
| 2018-02-26 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 12,274 | $0.00 |
| 2018-02-26 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 12,190 | $0.00 |
| 2018-02-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $0.00 |
| 2018-02-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $84.63 |
| 2018-02-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $38.59 |
| 2018-02-01 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 30,000 | $0.00 |
| 2018-02-01 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 30,000 | $38.59 |
| 2018-02-01 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 30,000 | $90.66 |
| 2018-01-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $90.32 |
| 2018-01-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $38.59 |
| 2018-01-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $0.00 |
| 2018-01-02 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 5,000 | $26.49 |
| 2018-01-02 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 3,750 | $38.59 |
| 2018-01-02 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 3,750 | $88.84 |
| 2018-01-02 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 3,750 | $0.00 |
| 2018-01-02 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 10,000 | $0.00 |
| 2018-01-02 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 5,000 | $0.00 |
| 2018-01-02 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 15,000 | $89.23 |
| 2018-01-02 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 10,000 | $37.46 |
| 2017-12-29 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $38.59 |
| 2017-12-29 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $89.61 |
| 2017-12-29 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $0.00 |
| 2017-12-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $38.59 |
| 2017-12-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $0.00 |
| 2017-12-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $89.89 |
| 2017-12-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 600 | $0.00 |
| 2017-12-14 | HERON, ELAINE J | Director | 普通株式 | 売却 | 800 | $88.90 |
| 2017-11-30 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 1,200 | $85.64 |
| 2017-09-29 | HOMBACH, ROBERT J. | Director | 普通株式 | 購入 | 3,180 | $0.00 |
| 2017-09-28 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 2,915 | $92.06 |
| 2017-09-28 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 15,500 | $92.50 |
| 2017-09-26 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 430 | $0.00 |
| 2017-09-22 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 2,166 | $0.00 |
| 2017-09-22 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 1,355 | $37.46 |
| 2017-09-22 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 1,355 | $95.00 |
| 2017-09-22 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 1,355 | $0.00 |
| 2017-09-22 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 2,166 | $95.00 |
| 2017-09-22 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 2,166 | $37.46 |
| 2017-09-15 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 10,000 | $0.00 |
| 2017-09-15 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 15,000 | $90.50 |
| 2017-09-15 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 5,000 | $26.49 |
| 2017-09-15 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 3,750 | $0.00 |
| 2017-09-15 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 3,750 | $91.26 |
| 2017-09-15 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 3,750 | $38.59 |
| 2017-09-15 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 10,000 | $37.46 |
| 2017-09-15 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 5,000 | $0.00 |
| 2017-06-23 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 9,844 | $38.59 |
| 2017-06-23 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 9,844 | $96.60 |
| 2017-06-23 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 9,844 | $0.00 |
| 2017-06-22 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 売却 | 2,671 | $100.00 |
| 2017-06-22 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 購入 | 2,671 | $21.51 |
| 2017-06-22 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 売却 | 2,671 | $0.00 |
| 2017-06-19 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 603 | $90.00 |
| 2017-06-19 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 603 | $37.46 |
| 2017-06-19 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 603 | $0.00 |
| 2017-06-16 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 5,000 | $26.49 |
| 2017-06-16 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 9,397 | $37.46 |
| 2017-06-16 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 5,000 | $90.00 |
| 2017-06-16 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 9,397 | $90.00 |
| 2017-06-16 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 5,000 | $0.00 |
| 2017-06-16 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 9,397 | $0.00 |
| 2017-06-16 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 3,750 | $38.59 |
| 2017-06-16 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 3,750 | $90.00 |
| 2017-06-16 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 3,750 | $0.00 |
| 2017-06-09 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 3,775 | $26.49 |
| 2017-06-09 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 5,464 | $21.51 |
| 2017-06-09 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 3,775 | $0.00 |
| 2017-06-09 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 5,464 | $0.00 |
| 2017-06-07 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 1,004 | $89.61 |
| 2017-06-06 | LEWIS, ALAN | Director | 普通株式 | 購入 | 2,050 | $0.00 |
| 2017-06-06 | LEWIS, ALAN | Director | 普通株式 | 購入 | 4,910 | $0.00 |
| 2017-06-06 | GREY, MICHAEL G | Director | 普通株式 | 購入 | 2,050 | $0.00 |
| 2017-06-06 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 2,050 | $0.00 |
| 2017-06-06 | DERE, WILLARD H | Director | 普通株式 | 購入 | 4,910 | $0.00 |
| 2017-06-06 | DERE, WILLARD H | Director | 普通株式 | 購入 | 2,050 | $0.00 |
| 2017-06-06 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 4,910 | $0.00 |
| 2017-06-06 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 2,050 | $0.00 |
| 2017-06-06 | HERON, ELAINE J | Director | 普通株式 | 購入 | 4,910 | $0.00 |
| 2017-06-06 | HERON, ELAINE J | Director | 普通株式 | 購入 | 2,050 | $0.00 |
| 2017-06-06 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 4,910 | $0.00 |
| 2017-06-06 | GREY, MICHAEL G | Director | 普通株式 | 購入 | 4,910 | $0.00 |
| 2017-06-06 | PYOTT, DAVID E I | Director | 普通株式 | 購入 | 2,050 | $0.00 |
| 2017-06-06 | PYOTT, DAVID E I | Director | 普通株式 | 購入 | 4,910 | $0.00 |
| 2017-06-06 | SLAMON, DENNIS | Director | 普通株式 | 購入 | 2,050 | $0.00 |
| 2017-06-06 | SLAMON, DENNIS | Director | 普通株式 | 購入 | 4,910 | $0.00 |
| 2017-06-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $90.56 |
| 2017-06-05 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 9,471 | $91.04 |
| 2017-06-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $17.33 |
| 2017-06-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2017-06-02 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 1,801 | $90.72 |
| 2017-06-02 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 売却 | 376 | $90.72 |
| 2017-06-02 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 2,036 | $90.72 |
| 2017-06-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 6,640 | $90.72 |
| 2017-06-02 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 1,488 | $90.72 |
| 2017-06-02 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 1,488 | $90.72 |
| 2017-06-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2017-06-02 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 1,644 | $90.72 |
| 2017-06-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $17.33 |
| 2017-06-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $89.70 |
| 2017-06-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2017-06-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $17.33 |
| 2017-06-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $87.53 |
| 2017-05-31 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 7,423 | $88.29 |
| 2017-05-31 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 7,423 | $17.33 |
| 2017-05-31 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 7,423 | $0.00 |
| 2017-05-24 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $17.33 |
| 2017-05-24 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $88.38 |
| 2017-05-24 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2017-05-17 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2017-05-17 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $17.33 |
| 2017-05-17 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $91.73 |
| 2017-05-16 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 1,146 | $14.39 |
| 2017-05-16 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 1,146 | $0.00 |
| 2017-05-15 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 売却 | 207 | $91.50 |
| 2017-05-15 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 1,096 | $91.50 |
| 2017-05-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,932 | $91.50 |
| 2017-05-15 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 1,722 | $91.50 |
| 2017-05-15 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 2,036 | $91.50 |
| 2017-05-15 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 1,566 | $91.50 |
| 2017-05-15 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 1,096 | $91.50 |
| 2017-05-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2017-05-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $17.33 |
| 2017-05-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $89.23 |
| 2017-05-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $17.33 |
| 2017-05-08 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 売却 | 2,600 | $0.00 |
| 2017-05-08 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 売却 | 2,600 | $93.17 |
| 2017-05-08 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 購入 | 2,600 | $21.51 |
| 2017-05-08 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 売却 | 4,882 | $91.17 |
| 2017-05-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2017-05-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $93.17 |
| 2017-05-05 | MEIER, RICHARD A | Director | 普通株式 | 売却 | 7,500 | $0.00 |
| 2017-05-05 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 988 | $99.00 |
| 2017-05-05 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 3,498 | $38.59 |
| 2017-05-05 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 3,498 | $99.00 |
| 2017-05-05 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 988 | $0.00 |
| 2017-05-05 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 3,498 | $0.00 |
| 2017-05-05 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 2,500 | $38.59 |
| 2017-05-05 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 2,500 | $100.34 |
| 2017-05-05 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 2,500 | $0.00 |
| 2017-05-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $17.33 |
| 2017-05-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $99.00 |
| 2017-05-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2017-05-05 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 7,500 | $17.33 |
| 2017-05-05 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 988 | $28.23 |
| 2017-05-02 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 302 | $96.74 |
| 2017-04-28 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 155 | $70.30 |
| 2017-04-28 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 302 | $70.30 |
| 2017-04-28 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 購入 | 270 | $70.30 |
| 2017-04-28 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 302 | $70.30 |
| 2017-04-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 302 | $70.30 |
| 2017-04-28 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 302 | $70.30 |
| 2017-04-28 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 302 | $70.30 |
| 2017-04-27 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $17.33 |
| 2017-04-27 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $95.72 |
| 2017-04-27 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2017-04-25 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $94.00 |
| 2017-04-25 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $17.33 |
| 2017-04-25 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2017-04-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 3,000 | $14.39 |
| 2017-04-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $0.00 |
| 2017-03-29 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 3,890 | $89.15 |
| 2017-03-22 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 11,870 | $0.00 |
| 2017-03-22 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 38,420 | $0.00 |
| 2017-03-22 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 11,220 | $0.00 |
| 2017-03-22 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 36,280 | $0.00 |
| 2017-03-22 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 44,520 | $0.00 |
| 2017-03-22 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 144,050 | $0.00 |
| 2017-03-22 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 購入 | 4,790 | $0.00 |
| 2017-03-22 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 購入 | 7,740 | $0.00 |
| 2017-03-22 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 19,790 | $0.00 |
| 2017-03-22 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 64,030 | $0.00 |
| 2017-03-22 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 39,480 | $0.00 |
| 2017-03-22 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 12,200 | $0.00 |
| 2017-03-22 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 12,200 | $0.00 |
| 2017-03-22 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 39,480 | $0.00 |
| 2017-03-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2017-03-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $71.33 |
| 2017-03-16 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 1,989 | $91.96 |
| 2017-03-16 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 売却 | 376 | $90.96 |
| 2017-03-16 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 2,238 | $91.96 |
| 2017-03-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $91.96 |
| 2017-03-15 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 2,995 | $92.50 |
| 2017-03-15 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 3,288 | $92.50 |
| 2017-03-15 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 5,116 | $92.50 |
| 2017-03-15 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 3,289 | $92.50 |
| 2017-03-15 | MUELLER, BRIAN | SVP, Corporate Controller | 普通株式 | 売却 | 336 | $92.50 |
| 2017-03-15 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 4,301 | $92.50 |
| 2017-03-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $17.33 |
| 2017-03-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $91.42 |
| 2017-03-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 15,690 | $92.50 |
| 2017-03-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2017-03-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2017-03-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $17.33 |
| 2017-03-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $92.68 |
| 2017-03-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $17.33 |
| 2017-03-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $91.09 |
| 2017-03-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2017-03-09 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 6,000 | $0.00 |
| 2017-03-09 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 6,000 | $90.18 |
| 2017-03-09 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 6,000 | $17.33 |
| 2017-03-07 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 5,000 | $90.56 |
| 2017-03-06 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 1,498 | $93.32 |
| 2017-03-06 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 2,303 | $93.32 |
| 2017-03-03 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 1,749 | $93.95 |
| 2017-03-03 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 2,924 | $93.95 |
| 2017-03-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 8,989 | $93.95 |
| 2017-03-03 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 2,283 | $93.95 |
| 2017-03-03 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 1,596 | $93.95 |
| 2017-03-03 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 1,749 | $93.95 |
| 2017-03-01 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 7,500 | $95.00 |
| 2017-03-01 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 7,500 | $0.00 |
| 2017-03-01 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 5,000 | $94.50 |
| 2017-03-01 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 7,500 | $17.33 |
| 2017-02-28 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 30,000 | $94.00 |
| 2017-02-28 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 30,000 | $0.00 |
| 2017-02-28 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 30,000 | $63.10 |
| 2017-02-24 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 44,671 | $0.00 |
| 2017-02-24 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 12,247 | $0.00 |
| 2017-02-24 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 11,917 | $95.61 |
| 2017-02-24 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 11,917 | $0.00 |
| 2017-02-24 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 11,258 | $0.00 |
| 2017-02-24 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 15,000 | $0.00 |
| 2017-02-24 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 15,000 | $87.99 |
| 2017-02-24 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 15,000 | $26.49 |
| 2017-02-24 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 14,564 | $0.00 |
| 2017-01-26 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2017-01-26 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $84.00 |
| 2017-01-26 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $17.33 |
| 2017-01-25 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $17.33 |
| 2017-01-25 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $84.44 |
| 2017-01-25 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2017-01-11 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $89.84 |
| 2017-01-11 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 4,000 | $17.33 |
| 2017-01-11 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $0.00 |
| 2017-01-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 4,000 | $17.33 |
| 2017-01-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $91.31 |
| 2017-01-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $0.00 |
| 2017-01-09 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 4,000 | $17.33 |
| 2017-01-09 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 5,000 | $90.00 |
| 2017-01-09 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $0.00 |
| 2017-01-09 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $89.79 |
| 2017-01-06 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $87.19 |
| 2017-01-06 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 4,000 | $17.33 |
| 2017-01-06 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $0.00 |
| 2016-12-30 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $0.00 |
| 2016-12-30 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $83.35 |
| 2016-12-30 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 4,000 | $17.33 |
| 2016-12-29 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 4,000 | $17.33 |
| 2016-12-29 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $83.84 |
| 2016-12-29 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $0.00 |
| 2016-11-25 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 15,000 | $0.00 |
| 2016-11-25 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 15,000 | $26.49 |
| 2016-11-25 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 売却 | 15,000 | $87.40 |
| 2016-11-22 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 69,743 | $26.49 |
| 2016-11-22 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 69,743 | $85.69 |
| 2016-11-22 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 69,743 | $0.00 |
| 2016-11-21 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 69,744 | $0.00 |
| 2016-11-21 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 69,744 | $26.49 |
| 2016-11-21 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 69,744 | $87.56 |
| 2016-11-18 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 5,000 | $38.59 |
| 2016-11-18 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 5,000 | $90.42 |
| 2016-11-18 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 5,000 | $38.59 |
| 2016-11-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 41,670 | $17.54 |
| 2016-11-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 41,670 | $90.97 |
| 2016-11-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 41,670 | $0.00 |
| 2016-11-09 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 20,000 | $90.61 |
| 2016-11-09 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 7,500 | $17.33 |
| 2016-11-09 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 7,500 | $95.00 |
| 2016-11-09 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 7,500 | $0.00 |
| 2016-11-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 70,000 | $21.51 |
| 2016-11-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 70,000 | $0.00 |
| 2016-11-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 70,000 | $82.83 |
| 2016-11-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 70,000 | $21.51 |
| 2016-11-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 70,000 | $82.52 |
| 2016-11-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 70,000 | $0.00 |
| 2016-10-31 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 156 | $68.44 |
| 2016-10-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 60,000 | $14.39 |
| 2016-10-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 60,000 | $81.27 |
| 2016-10-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 60,000 | $0.00 |
| 2016-10-27 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 60,000 | $81.34 |
| 2016-10-27 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 60,000 | $0.00 |
| 2016-10-27 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 60,000 | $14.39 |
| 2016-10-17 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 41,666 | $17.54 |
| 2016-10-17 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 41,666 | $84.39 |
| 2016-10-17 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 41,666 | $0.00 |
| 2016-10-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 11,000 | $0.00 |
| 2016-10-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 11,000 | $86.89 |
| 2016-10-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 11,000 | $17.86 |
| 2016-10-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 53,125 | $0.00 |
| 2016-10-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 53,125 | $86.98 |
| 2016-10-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 53,125 | $38.59 |
| 2016-10-07 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 360 | $0.00 |
| 2016-09-30 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 53,125 | $38.59 |
| 2016-09-30 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 53,125 | $0.00 |
| 2016-09-30 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 53,125 | $92.02 |
| 2016-09-29 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 53,125 | $93.65 |
| 2016-09-29 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 53,125 | $0.00 |
| 2016-09-29 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 53,125 | $38.59 |
| 2016-09-27 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 18,467 | $95.61 |
| 2016-09-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 41,666 | $95.97 |
| 2016-09-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 53,125 | $95.25 |
| 2016-09-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 53,125 | $38.59 |
| 2016-09-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 41,666 | $0.00 |
| 2016-09-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 53,125 | $0.00 |
| 2016-09-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 41,666 | $17.54 |
| 2016-09-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 42,577 | $0.00 |
| 2016-09-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 42,577 | $17.33 |
| 2016-09-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 42,577 | $94.85 |
| 2016-08-26 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 15,000 | $0.00 |
| 2016-08-26 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 15,000 | $95.06 |
| 2016-08-26 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 15,000 | $26.49 |
| 2016-08-24 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 200 | $0.00 |
| 2016-08-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 41,666 | $91.49 |
| 2016-08-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 41,666 | $17.54 |
| 2016-08-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 41,666 | $0.00 |
| 2016-08-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 500 | $0.00 |
| 2016-08-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 400 | $0.00 |
| 2016-08-01 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 287 | $100.00 |
| 2016-08-01 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 2,167 | $100.00 |
| 2016-08-01 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 4,000 | $99.33 |
| 2016-07-27 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 1,100 | $95.39 |
| 2016-07-27 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 1,100 | $17.33 |
| 2016-07-27 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 1,100 | $0.00 |
| 2016-07-22 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 6,400 | $17.33 |
| 2016-07-22 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 6,400 | $95.01 |
| 2016-07-22 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 6,400 | $0.00 |
| 2016-07-18 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 41,666 | $0.00 |
| 2016-07-18 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 41,666 | $92.72 |
| 2016-07-18 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 41,666 | $17.54 |
| 2016-07-15 | DERE, WILLARD H | Director | 普通株式 | 購入 | 9,880 | $0.00 |
| 2016-07-15 | FALBERG, KATHRYN E | Director | 普通株式 | 購入 | 8,230 | $0.00 |
| 2016-07-15 | DERE, WILLARD H | Director | 普通株式 | 購入 | 3,300 | $0.00 |
| 2016-07-15 | DERE, WILLARD H | Director | 普通株式 | 購入 | 8,230 | $0.00 |
| 2016-07-15 | FALBERG, KATHRYN E | Director | 普通株式 | 購入 | 2,640 | $0.00 |
| 2016-07-15 | DERE, WILLARD H | Director | 普通株式 | 購入 | 2,640 | $0.00 |
| 2016-07-15 | FALBERG, KATHRYN E | Director | 普通株式 | 購入 | 9,880 | $0.00 |
| 2016-07-15 | FALBERG, KATHRYN E | Director | 普通株式 | 購入 | 3,300 | $0.00 |
| 2016-07-14 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 2,656 | $38.59 |
| 2016-07-14 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 2,656 | $38.59 |
| 2016-07-07 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 2,167 | $90.00 |
| 2016-06-20 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 550 | $82.77 |
| 2016-06-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 41,666 | $80.55 |
| 2016-06-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 41,666 | $0.00 |
| 2016-06-16 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 120 | $0.00 |
| 2016-06-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 41,666 | $17.54 |
| 2016-06-06 | LEWIS, ALAN | Director | 普通株式 | 購入 | 1,510 | $ |
| 2016-06-06 | LEWIS, ALAN | Director | 普通株式 | 購入 | 4,440 | $0.00 |
| 2016-06-06 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 1,510 | $0.00 |
| 2016-06-06 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 4,440 | $0.00 |
| 2016-06-06 | HERON, ELAINE J | Director | 普通株式 | 購入 | 1,510 | $0.00 |
| 2016-06-06 | GREY, MICHAEL G | Director | 普通株式 | 購入 | 4,440 | $0.00 |
| 2016-06-06 | SLAMON, DENNIS | Director | 普通株式 | 購入 | 4,440 | $0.00 |
| 2016-06-06 | SLAMON, DENNIS | Director | 普通株式 | 購入 | 1,510 | $ |
| 2016-06-06 | GREY, MICHAEL G | Director | 普通株式 | 購入 | 1,510 | $0.00 |
| 2016-06-06 | HERON, ELAINE J | Director | 普通株式 | 購入 | 4,440 | $0.00 |
| 2016-06-06 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 1,649 | $89.14 |
| 2016-06-06 | PYOTT, DAVID E I | Director | 普通株式 | 購入 | 2,220 | $0.00 |
| 2016-06-06 | PYOTT, DAVID E I | Director | 普通株式 | 購入 | 760 | $0.00 |
| 2016-06-06 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 1,510 | $ |
| 2016-06-06 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 0 | $0.00 |
| 2016-06-06 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 4,440 | $0.00 |
| 2016-06-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 6,640 | $90.00 |
| 2016-06-03 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 1,644 | $90.00 |
| 2016-06-03 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 1,488 | $90.00 |
| 2016-06-03 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 1,801 | $90.00 |
| 2016-06-03 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 376 | $90.00 |
| 2016-06-03 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 2,036 | $90.00 |
| 2016-06-03 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 1,488 | $90.00 |
| 2016-05-31 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 16,896 | $0.00 |
| 2016-05-31 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 16,896 | $39.06 |
| 2016-05-31 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 3,945 | $89.35 |
| 2016-05-31 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 16,896 | $0.00 |
| 2016-05-31 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 16,896 | $90.00 |
| 2016-05-27 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 4,305 | $89.09 |
| 2016-05-26 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 15,000 | $26.49 |
| 2016-05-26 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 5,000 | $87.34 |
| 2016-05-26 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 15,000 | $0.00 |
| 2016-05-26 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 10,000 | $88.04 |
| 2016-05-23 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 3,769 | $87.07 |
| 2016-05-18 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 5,000 | $87.05 |
| 2016-05-13 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 1,722 | $82.71 |
| 2016-05-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,932 | $82.71 |
| 2016-05-13 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 1,096 | $82.71 |
| 2016-05-13 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 1,096 | $82.71 |
| 2016-05-13 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 2,036 | $82.71 |
| 2016-05-13 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 207 | $82.71 |
| 2016-05-13 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 1,566 | $82.71 |
| 2016-05-10 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 4,658 | $86.32 |
| 2016-05-09 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 10,000 | $84.55 |
| 2016-05-06 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 679 | $80.80 |
| 2016-05-06 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 2,088 | $80.80 |
| 2016-05-06 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 1,696 | $80.80 |
| 2016-05-06 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,479 | $80.80 |
| 2016-05-06 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 3,131 | $80.80 |
| 2016-05-06 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 444 | $80.80 |
| 2016-05-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 20,000 | $12.99 |
| 2016-05-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 20,000 | $0.00 |
| 2016-05-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $12.99 |
| 2016-05-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 20,000 | $80.15 |
| 2016-05-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $80.15 |
| 2016-05-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $0.00 |
| 2016-05-03 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 売却 | 415 | $86.03 |
| 2016-05-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 36,500 | $0.00 |
| 2016-05-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 36,500 | $85.01 |
| 2016-05-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 36,500 | $12.99 |
| 2016-04-29 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 414 | $51.26 |
| 2016-04-29 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 327 | $51.26 |
| 2016-04-29 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 414 | $51.26 |
| 2016-04-29 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 415 | $51.26 |
| 2016-04-29 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 202 | $51.26 |
| 2016-04-29 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 414 | $51.26 |
| 2016-04-29 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 415 | $51.26 |
| 2016-04-06 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,500 | $14.39 |
| 2016-04-06 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,500 | $0.00 |
| 2016-04-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,500 | $14.39 |
| 2016-04-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,500 | $0.00 |
| 2016-03-16 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 376 | $80.34 |
| 2016-03-15 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 0 | $0.00 |
| 2016-03-15 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 44,340 | $0.00 |
| 2016-03-15 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 16,190 | $0.00 |
| 2016-03-15 | AJER, JEFFREY ROBERT | EVP, Chief Commercial Officer | 普通株式 | 購入 | 36,280 | $0.00 |
| 2016-03-15 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 15,290 | $0.00 |
| 2016-03-15 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 34,270 | $0.00 |
| 2016-03-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 60,710 | $0.00 |
| 2016-03-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 136,050 | $0.00 |
| 2016-03-15 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 16,640 | $0.00 |
| 2016-03-15 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 37,290 | $0.00 |
| 2016-03-15 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 16,190 | $0.00 |
| 2016-03-15 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 36,280 | $0.00 |
| 2016-03-15 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 19,790 | $0.00 |
| 2016-03-15 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 3,570 | $0.00 |
| 2016-03-15 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 7,000 | $0.00 |
| 2016-03-14 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 1,996 | $86.21 |
| 2016-03-07 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 2,191 | $0.00 |
| 2016-03-07 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 2,191 | $0.00 |
| 2016-03-04 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Officer | 普通株式 | 売却 | 1,255 | $88.42 |
| 2016-03-03 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 3,043 | $89.57 |
| 2016-03-03 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 2,180 | $89.57 |
| 2016-03-03 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 45,727 | $0.00 |
| 2016-03-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 8,989 | $89.57 |
| 2016-03-03 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 2,395 | $89.57 |
| 2016-03-03 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Officer | 普通株式 | 売却 | 2,395 | $89.57 |
| 2016-03-03 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 45,727 | $0.00 |
| 2016-03-03 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 2,395 | $89.57 |
| 2016-03-02 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 4,623 | $86.12 |
| 2016-03-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,151 | $84.22 |
| 2016-03-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,828 | $84.24 |
| 2016-03-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,021 | $84.33 |
| 2016-02-29 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 192,982 | $81.87 |
| 2016-02-29 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 47,273 | $81.87 |
| 2016-02-29 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 46,766 | $81.87 |
| 2016-02-29 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 売却 | 17,656 | $81.87 |
| 2016-02-29 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Officer | 普通株式 | 売却 | 17,656 | $81.87 |
| 2016-02-29 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 56,464 | $81.87 |
| 2016-02-24 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 5,883 | $0.00 |
| 2016-02-24 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 6,860 | $0.00 |
| 2016-02-24 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 19,840 | $0.00 |
| 2016-02-24 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 5,883 | $0.00 |
| 2016-02-24 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 17,150 | $0.00 |
| 2016-02-24 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 49,600 | $0.00 |
| 2016-02-24 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 17,150 | $0.00 |
| 2016-02-24 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 49,600 | $0.00 |
| 2016-02-24 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 5,883 | $0.00 |
| 2016-02-24 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 94,850 | $0.00 |
| 2016-02-24 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 198,400 | $0.00 |
| 2016-02-24 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 21,978 | $0.00 |
| 2016-02-24 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 6,860 | $0.00 |
| 2016-02-24 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 19,840 | $0.00 |
| 2016-02-24 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 5,328 | $0.00 |
| 2016-02-24 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 20,580 | $0.00 |
| 2016-02-24 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 59,520 | $0.00 |
| 2016-02-24 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 7,437 | $0.00 |
| 2016-02-22 | GREY, MICHAEL G | Director | 普通株式 | 購入 | 7,500 | $38.59 |
| 2016-02-22 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 7,500 | $80.00 |
| 2016-02-22 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 7,500 | $0.00 |
| 2016-01-07 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 2,675 | $0.00 |
| 2016-01-07 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 2,675 | $0.00 |
| 2016-01-04 | PYOTT, DAVID E I | Director | 普通株式 | 購入 | 2,100 | $0.00 |
| 2016-01-04 | PYOTT, DAVID E I | Director | 普通株式 | 購入 | 6,100 | $0.00 |
| 2015-12-16 | DAVIS, GEORGE ERIC | EVP, General Counsel | 普通株式 | 購入 | 0 | $0.00 |
| 2015-12-16 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 1,362 | $100.00 |
| 2015-11-30 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $94.74 |
| 2015-11-16 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 1,050 | $104.26 |
| 2015-11-16 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 7,500 | $107.27 |
| 2015-11-16 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 7,500 | $0.00 |
| 2015-11-16 | GREY, MICHAEL G | Director | 普通株式 | 購入 | 7,500 | $38.59 |
| 2015-11-16 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 7,500 | $104.27 |
| 2015-11-16 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 7,500 | $0.00 |
| 2015-11-16 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 20,000 | $39.06 |
| 2015-11-16 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 20,000 | $104.30 |
| 2015-11-16 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 20,000 | $0.00 |
| 2015-11-16 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 7,500 | $17.33 |
| 2015-11-02 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 26 | $117.56 |
| 2015-10-30 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 26 | $57.26 |
| 2015-10-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $108.24 |
| 2015-09-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $131.43 |
| 2015-09-08 | HERON, ELAINE J | Director | 普通株式 | 売却 | 15,000 | $0.00 |
| 2015-09-08 | HERON, ELAINE J | Director | 普通株式 | 購入 | 15,000 | $21.51 |
| 2015-08-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,500 | $134.72 |
| 2015-07-20 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 3,000 | $0.00 |
| 2015-07-20 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 3,000 | $63.10 |
| 2015-07-20 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 3,000 | $150.00 |
| 2015-07-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,500 | $139.07 |
| 2015-07-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 500 | $0.00 |
| 2015-06-10 | SLAMON, DENNIS | Director | ストックオプション | 購入 | 3,300 | $0.00 |
| 2015-06-10 | MEIER, RICHARD A | Director | ストックオプション | 購入 | 3,300 | $0.00 |
| 2015-06-10 | LEWIS, ALAN | Director | 普通株式 | 購入 | 1,100 | $ |
| 2015-06-10 | LEWIS, ALAN | Director | 普通株式 | 購入 | 3,300 | $0.00 |
| 2015-06-10 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 1,100 | $ |
| 2015-06-10 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 3,300 | $0.00 |
| 2015-06-10 | LAPALME, PIERRE | Director | 普通株式 | 購入 | 1,100 | $ |
| 2015-06-10 | LAPALME, PIERRE | Director | ストックオプション | 購入 | 3,300 | $0.00 |
| 2015-06-10 | BATE, KENNETH | Director | ストックオプション | 購入 | 3,300 | $0.00 |
| 2015-06-10 | BATE, KENNETH | Director | 普通株式 | 購入 | 1,100 | $ |
| 2015-06-10 | GREY, MICHAEL G | Director | 普通株式 | 購入 | 3,300 | $0.00 |
| 2015-06-10 | GREY, MICHAEL G | Director | 普通株式 | 購入 | 1,100 | $ |
| 2015-06-10 | HERON, ELAINE J | Director | 普通株式 | 購入 | 3,300 | $0.00 |
| 2015-06-10 | HERON, ELAINE J | Director | 普通株式 | 購入 | 1,100 | $ |
| 2015-06-10 | YOUNG, WILLIAM D | Director | 普通株式 | 購入 | 1,100 | $ |
| 2015-06-10 | YOUNG, WILLIAM D | Director | ストックオプション | 購入 | 3,300 | $0.00 |
| 2015-06-10 | SLAMON, DENNIS | Director | 普通株式 | 購入 | 1,100 | $ |
| 2015-06-10 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 1,100 | $ |
| 2015-06-08 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 120 | $0.00 |
| 2015-06-05 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 1,506 | $0.00 |
| 2015-06-05 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 1,864 | $122.32 |
| 2015-06-05 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 1,649 | $122.30 |
| 2015-06-05 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 1,506 | $0.00 |
| 2015-06-04 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 1,488 | $120.46 |
| 2015-06-04 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 1,488 | $120.46 |
| 2015-06-04 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 2,036 | $120.46 |
| 2015-06-04 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 522 | $120.46 |
| 2015-06-04 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 1,362 | $122.35 |
| 2015-06-04 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 1,644 | $120.46 |
| 2015-06-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 6,640 | $120.46 |
| 2015-06-04 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 1,801 | $120.46 |
| 2015-06-01 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 377 | $123.76 |
| 2015-06-01 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 3,945 | $124.16 |
| 2015-05-31 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 413 | $125.57 |
| 2015-05-31 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 308 | $125.57 |
| 2015-05-29 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 1,578 | $126.15 |
| 2015-05-29 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 4,305 | $125.57 |
| 2015-05-27 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 34,078 | $130.00 |
| 2015-05-27 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 34,078 | $0.00 |
| 2015-05-27 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 34,078 | $67.81 |
| 2015-05-26 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 1,625 | $126.55 |
| 2015-05-21 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,500 | $126.10 |
| 2015-05-19 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 1,434 | $0.00 |
| 2015-05-19 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 1,434 | $0.00 |
| 2015-05-18 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 2,558 | $125.26 |
| 2015-05-18 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 34,078 | $130.00 |
| 2015-05-18 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 2,059 | $124.77 |
| 2015-05-18 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 1,864 | $124.78 |
| 2015-05-15 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 1,566 | $122.78 |
| 2015-05-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,932 | $122.78 |
| 2015-05-15 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 1,096 | $122.78 |
| 2015-05-15 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 1,096 | $122.78 |
| 2015-05-15 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 2,036 | $122.78 |
| 2015-05-15 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 207 | $122.78 |
| 2015-05-15 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 1,722 | $122.78 |
| 2015-05-13 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 1,434 | $121.37 |
| 2015-05-12 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 1,566 | $121.09 |
| 2015-05-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,349 | $121.09 |
| 2015-05-11 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 2,869 | $121.64 |
| 2015-05-08 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 1,912 | $0.00 |
| 2015-05-08 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 1,912 | $0.00 |
| 2015-05-08 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 2,088 | $121.66 |
| 2015-05-08 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 1,696 | $121.66 |
| 2015-05-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,479 | $121.66 |
| 2015-05-08 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 679 | $121.66 |
| 2015-05-08 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 3,131 | $121.66 |
| 2015-05-08 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 444 | $121.66 |
| 2015-05-06 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 8,671 | $37.46 |
| 2015-05-06 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 33,631 | $119.14 |
| 2015-05-06 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 5,258 | $0.00 |
| 2015-05-06 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 625 | $0.00 |
| 2015-05-06 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 12,502 | $0.00 |
| 2015-05-06 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 12,502 | $38.59 |
| 2015-05-06 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 625 | $21.51 |
| 2015-05-06 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 3,125 | $21.51 |
| 2015-05-06 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 2,642 | $28.23 |
| 2015-05-06 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 5,258 | $28.23 |
| 2015-05-06 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 808 | $37.46 |
| 2015-05-06 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 8,671 | $0.00 |
| 2015-05-06 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 808 | $0.00 |
| 2015-05-06 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 2,642 | $0.00 |
| 2015-05-06 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 3,125 | $0.00 |
| 2015-05-06 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 388 | $119.20 |
| 2015-05-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,505 | $114.98 |
| 2015-05-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 414 | $114.59 |
| 2015-05-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 23,218 | $6.46 |
| 2015-05-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 23,218 | $114.98 |
| 2015-04-30 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 908 | $51.26 |
| 2015-04-30 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 1,425 | $51.26 |
| 2015-04-30 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 943 | $51.26 |
| 2015-04-30 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 389 | $0.00 |
| 2015-04-30 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 389 | $0.00 |
| 2015-04-30 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 389 | $51.26 |
| 2015-04-30 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 730 | $51.26 |
| 2015-04-30 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 607 | $51.26 |
| 2015-04-30 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 88 | $51.26 |
| 2015-04-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 23,218 | $0.00 |
| 2015-04-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 22,546 | $0.00 |
| 2015-04-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,506 | $120.53 |
| 2015-04-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 22,546 | $120.53 |
| 2015-04-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 22,546 | $6.46 |
| 2015-03-20 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $126.40 |
| 2015-03-17 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $124.87 |
| 2015-03-16 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 34,155 | $0.00 |
| 2015-03-16 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 4,000 | $0.00 |
| 2015-03-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $123.48 |
| 2015-03-16 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 41,315 | $123.57 |
| 2015-03-16 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 5,845 | $0.00 |
| 2015-03-16 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 5,845 | $21.51 |
| 2015-03-16 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 9,000 | $0.00 |
| 2015-03-16 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 34,155 | $21.51 |
| 2015-03-13 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 516 | $26.49 |
| 2015-03-13 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 14,484 | $37.46 |
| 2015-03-13 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 15,000 | $120.87 |
| 2015-03-13 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 516 | $0.00 |
| 2015-03-13 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 14,484 | $0.00 |
| 2015-03-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,021 | $114.89 |
| 2015-03-09 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 15,000 | $12.99 |
| 2015-03-09 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 15,000 | $112.12 |
| 2015-03-09 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $112.14 |
| 2015-03-09 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 15,000 | $0.00 |
| 2015-03-05 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 3,051 | $14.39 |
| 2015-03-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $0.00 |
| 2015-03-05 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 11,000 | $17.86 |
| 2015-03-05 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 3,051 | $0.00 |
| 2015-03-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $113.70 |
| 2015-03-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $12.99 |
| 2015-03-05 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 11,000 | $0.00 |
| 2015-03-05 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 14,051 | $116.37 |
| 2015-03-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 500 | $9.86 |
| 2015-03-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 916 | $107.71 |
| 2015-03-03 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 10,000 | $0.00 |
| 2015-03-03 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 21,900 | $0.00 |
| 2015-03-03 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 10,500 | $0.00 |
| 2015-03-03 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 23,900 | $0.00 |
| 2015-03-03 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 13,400 | $0.00 |
| 2015-03-03 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 30,500 | $0.00 |
| 2015-03-03 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 10,500 | $0.00 |
| 2015-03-03 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 23,900 | $0.00 |
| 2015-03-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $107.42 |
| 2015-03-03 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 20,000 | $106.57 |
| 2015-03-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 39,600 | $0.00 |
| 2015-03-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 90,500 | $0.00 |
| 2015-03-03 | FUCHS, HENRY J | President, Worldwide R&D | 普通株式 | 購入 | 0 | $0.00 |
| 2015-03-03 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 9,600 | $0.00 |
| 2015-03-03 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 10,500 | $0.00 |
| 2015-03-03 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 23,900 | $0.00 |
| 2015-03-03 | LAPALME, PIERRE | Director | 普通株式 | 購入 | 10,000 | $11.15 |
| 2015-03-03 | LAPALME, PIERRE | Director | 普通株式 | 購入 | 10,000 | $17.33 |
| 2015-03-03 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 7,000 | $28.23 |
| 2015-03-03 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 7,000 | $109.46 |
| 2015-03-02 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 23,000 | $26.49 |
| 2015-03-02 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 23,000 | $108.31 |
| 2015-03-02 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 15,500 | $0.00 |
| 2015-03-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $0.00 |
| 2015-03-02 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 15,500 | $107.00 |
| 2015-03-02 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 15,500 | $39.06 |
| 2015-03-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $108.44 |
| 2015-03-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $107.96 |
| 2015-03-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 3,000 | $12.99 |
| 2015-03-02 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 20,000 | $26.49 |
| 2015-01-09 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $94.14 |
| 2014-12-24 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $88.73 |
| 2014-12-24 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $88.73 |
| 2014-12-24 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $0.00 |
| 2014-12-24 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 3,000 | $12.99 |
| 2014-12-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $95.00 |
| 2014-12-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $0.00 |
| 2014-12-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 2,000 | $12.99 |
| 2014-12-04 | LEWIS, ALAN | Director | 普通株式 | 売却 | 7,500 | $89.90 |
| 2014-12-04 | LEWIS, ALAN | Director | ストックオプション | 売却 | 7,500 | $0.00 |
| 2014-12-04 | LEWIS, ALAN | Director | 普通株式 | 購入 | 7,500 | $21.51 |
| 2014-12-03 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 12,000 | $91.01 |
| 2014-12-03 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 12,000 | $38.59 |
| 2014-12-03 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 12,000 | $0.00 |
| 2014-12-02 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 5,000 | $0.00 |
| 2014-12-02 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 7,000 | $0.00 |
| 2014-12-02 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 5,000 | $28.23 |
| 2014-12-02 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 5,000 | $91.82 |
| 2014-12-01 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 6,429 | $0.00 |
| 2014-12-01 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 521 | $0.00 |
| 2014-12-01 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 521 | $14.39 |
| 2014-12-01 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 6,950 | $90.25 |
| 2014-12-01 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 6,429 | $21.51 |
| 2014-11-26 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 3,400 | $88.97 |
| 2014-11-25 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $0.00 |
| 2014-11-25 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 20,000 | $26.49 |
| 2014-11-25 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $90.00 |
| 2014-11-25 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 20,000 | $89.75 |
| 2014-11-25 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 2,000 | $12.99 |
| 2014-11-25 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 20,000 | $26.49 |
| 2014-11-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $85.51 |
| 2014-11-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $81.51 |
| 2014-11-10 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 20,000 | $86.55 |
| 2014-11-10 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 20,000 | $21.51 |
| 2014-11-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $87.00 |
| 2014-11-10 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 20,000 | $0.00 |
| 2014-11-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 4,000 | $12.99 |
| 2014-11-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $0.00 |
| 2014-11-03 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 47 | $83.54 |
| 2014-11-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $85.33 |
| 2014-10-31 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 47 | $31.26 |
| 2014-10-30 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 27,372 | $0.00 |
| 2014-10-30 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 15,000 | $26.49 |
| 2014-10-30 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 15,000 | $83.20 |
| 2014-10-30 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 15,000 | $26.49 |
| 2014-10-30 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 27,372 | $38.59 |
| 2014-10-30 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 2,591 | $38.59 |
| 2014-10-30 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 29,963 | $81.70 |
| 2014-10-30 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 2,591 | $0.00 |
| 2014-10-29 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 4,655 | $0.00 |
| 2014-10-29 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 35,037 | $0.00 |
| 2014-10-29 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 5,770 | $0.00 |
| 2014-10-29 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 35,037 | $38.59 |
| 2014-10-29 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 45,462 | $81.10 |
| 2014-10-29 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 5,770 | $17.33 |
| 2014-10-29 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 4,655 | $17.54 |
| 2014-10-24 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $80.00 |
| 2014-10-24 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 2,000 | $12.99 |
| 2014-10-24 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $0.00 |
| 2014-10-21 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 2,000 | $12.99 |
| 2014-10-21 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $75.00 |
| 2014-09-19 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 17,536 | $69.75 |
| 2014-09-19 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 17,536 | $21.51 |
| 2014-09-19 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 17,536 | $21.51 |
| 2014-09-03 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 9 | $69.83 |
| 2014-09-03 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 9 | $69.70 |
| 2014-09-02 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | ストックオプション | 売却 | 16,000 | $0.00 |
| 2014-09-02 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 16,000 | $69.83 |
| 2014-09-02 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 16,000 | $39.06 |
| 2014-08-20 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $0.00 |
| 2014-08-20 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2014-08-20 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $70.00 |
| 2014-08-20 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $12.99 |
| 2014-08-06 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 7 | $62.17 |
| 2014-08-06 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 7 | $62.18 |
| 2014-08-05 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 10,000 | $65.00 |
| 2014-08-05 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 10,000 | $21.51 |
| 2014-08-05 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 10,000 | $0.00 |
| 2014-08-01 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 2,229 | $61.76 |
| 2014-07-02 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 2,229 | $64.00 |
| 2014-06-06 | GREY, MICHAEL G | Director | 普通株式 | 購入 | 2,100 | $0.00 |
| 2014-06-04 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 11,400 | $0.00 |
| 2014-06-04 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 58,400 | $0.00 |
| 2014-06-04 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 15,600 | $0.00 |
| 2014-06-04 | BATE, KENNETH | Director | ストックオプション | 購入 | 6,600 | $0.00 |
| 2014-06-04 | BATE, KENNETH | Director | 普通株式 | 購入 | 2,100 | $ |
| 2014-06-04 | HERON, ELAINE J | Director | 普通株式 | 購入 | 6,600 | $0.00 |
| 2014-06-04 | HERON, ELAINE J | Director | 普通株式 | 購入 | 2,100 | $0.00 |
| 2014-06-04 | LAPALME, PIERRE | Director | 普通株式 | 購入 | 6,600 | $0.00 |
| 2014-06-04 | LAPALME, PIERRE | Director | 普通株式 | 購入 | 2,100 | $0.00 |
| 2014-06-04 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 6,600 | $0.00 |
| 2014-06-04 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 2,100 | $0.00 |
| 2014-06-04 | YOUNG, WILLIAM D | Director | ストックオプション | 購入 | 6,600 | $0.00 |
| 2014-06-04 | YOUNG, WILLIAM D | Director | 普通株式 | 購入 | 2,100 | $0.00 |
| 2014-06-04 | MEIER, RICHARD A | Director | ストックオプション | 購入 | 6,600 | $0.00 |
| 2014-06-04 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 2,100 | $0.00 |
| 2014-06-04 | LEWIS, ALAN | Director | ストックオプション | 購入 | 6,600 | $0.00 |
| 2014-06-04 | SLAMON, DENNIS | Director | ストックオプション | 購入 | 1,500 | $0.00 |
| 2014-06-04 | SLAMON, DENNIS | Director | 普通株式 | 購入 | 525 | $0.00 |
| 2014-06-04 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 11,400 | $0.00 |
| 2014-06-04 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 4,000 | $0.00 |
| 2014-06-04 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 10,000 | $0.00 |
| 2014-06-04 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 42,700 | $0.00 |
| 2014-06-04 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 51,700 | $0.00 |
| 2014-06-04 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 47,200 | $0.00 |
| 2014-06-04 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 12,600 | $0.00 |
| 2014-06-04 | LEWIS, ALAN | Director | 普通株式 | 購入 | 2,100 | $0.00 |
| 2014-06-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 191,000 | $0.00 |
| 2014-06-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 50,900 | $0.00 |
| 2014-06-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $62.52 |
| 2014-06-04 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 13,800 | $0.00 |
| 2014-06-04 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 42,700 | $0.00 |
| 2014-06-04 | GREY, MICHAEL G | Director | 普通株式 | 購入 | 6,600 | $0.00 |
| 2014-06-03 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 3,562 | $60.00 |
| 2014-06-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $59.88 |
| 2014-06-02 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 377 | $57.83 |
| 2014-05-31 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 297 | $57.96 |
| 2014-05-31 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 413 | $57.96 |
| 2014-05-30 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 180 | $23.21 |
| 2014-05-29 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 3,792 | $57.50 |
| 2014-05-22 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $56.88 |
| 2014-05-21 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,545 | $56.19 |
| 2014-05-16 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 1,864 | $56.86 |
| 2014-05-16 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 1,004 | $56.91 |
| 2014-05-16 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 1,700 | $56.87 |
| 2014-05-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,932 | $57.44 |
| 2014-05-15 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 1,096 | $57.44 |
| 2014-05-15 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 1,241 | $57.44 |
| 2014-05-15 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 207 | $57.44 |
| 2014-05-15 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 2,036 | $57.44 |
| 2014-05-13 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 1,434 | $58.23 |
| 2014-05-13 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 478 | $58.18 |
| 2014-05-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,567 | $59.30 |
| 2014-05-12 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 3,001 | $59.30 |
| 2014-05-12 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 1,096 | $57.44 |
| 2014-05-12 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 522 | $59.30 |
| 2014-05-12 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 1,096 | $59.30 |
| 2014-05-12 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 1,566 | $59.30 |
| 2014-05-12 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 282 | $59.30 |
| 2014-05-09 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 3,479 | $57.91 |
| 2014-05-09 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 621 | $57.96 |
| 2014-05-08 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 1,696 | $56.78 |
| 2014-05-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,479 | $56.78 |
| 2014-05-08 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 679 | $56.78 |
| 2014-05-08 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 444 | $56.78 |
| 2014-05-08 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 2,521 | $56.78 |
| 2014-05-02 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 3 | $58.02 |
| 2014-05-02 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 8 | $58.78 |
| 2014-05-01 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 666 | $59.55 |
| 2014-05-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 715 | $59.67 |
| 2014-04-30 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 666 | $29.70 |
| 2014-04-30 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 704 | $29.69 |
| 2014-04-30 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 94 | $49.50 |
| 2014-04-30 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 715 | $29.69 |
| 2014-04-30 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 498 | $29.69 |
| 2014-04-30 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 715 | $29.69 |
| 2014-03-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $0.00 |
| 2014-03-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 2,000 | $12.99 |
| 2014-03-19 | SLAMON, DENNIS | Director | 普通株式 | 購入 | 4,000 | $0.00 |
| 2014-03-19 | SLAMON, DENNIS | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2014-03-06 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 2,558 | $21.51 |
| 2014-03-06 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 14,812 | $0.00 |
| 2014-03-06 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 2,558 | $0.00 |
| 2014-03-06 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 17,370 | $78.63 |
| 2014-03-06 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 14,812 | $28.23 |
| 2014-03-05 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 12 | $82.93 |
| 2014-03-03 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | ストックオプション | 売却 | 8,000 | $0.00 |
| 2014-03-03 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 8,000 | $80.32 |
| 2014-03-03 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 8,000 | $39.06 |
| 2014-02-20 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 20,000 | $80.00 |
| 2014-02-20 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 20,000 | $21.51 |
| 2014-02-20 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 8,000 | $80.00 |
| 2014-02-20 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 20,000 | $21.51 |
| 2014-02-14 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 31,500 | $0.00 |
| 2014-02-14 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 26,250 | $0.00 |
| 2014-02-14 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 10,500 | $0.00 |
| 2014-02-14 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 26,250 | $0.00 |
| 2014-02-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 78,750 | $0.00 |
| 2014-02-14 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 10,500 | $0.00 |
| 2014-02-06 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 4,000 | $12.99 |
| 2014-02-06 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $0.00 |
| 2014-02-04 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 2,675 | $0.00 |
| 2014-02-04 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 2,675 | $0.00 |
| 2014-02-03 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 10,000 | $21.51 |
| 2014-02-03 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 10,000 | $67.70 |
| 2014-02-03 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 10,000 | $0.00 |
| 2014-01-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2014-01-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $12.99 |
| 2014-01-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $70.00 |
| 2014-01-06 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $67.40 |
| 2014-01-06 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $0.00 |
| 2014-01-06 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $67.42 |
| 2014-01-06 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $12.99 |
| 2014-01-02 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 916 | $68.97 |
| 2014-01-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $12.99 |
| 2014-01-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2014-01-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $68.90 |
| 2013-12-24 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $0.00 |
| 2013-12-24 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $12.99 |
| 2013-12-24 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $68.71 |
| 2013-12-11 | GREY, MICHAEL G | Director | ストックオプション | 売却 | 7,500 | $0.00 |
| 2013-12-11 | GREY, MICHAEL G | Director | ストックオプション | 売却 | 7,500 | $0.00 |
| 2013-12-11 | GREY, MICHAEL G | Director | ストックオプション | 売却 | 15,000 | $0.00 |
| 2013-12-11 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 30,000 | $69.66 |
| 2013-12-11 | GREY, MICHAEL G | Director | 普通株式 | 購入 | 7,500 | $26.49 |
| 2013-12-11 | GREY, MICHAEL G | Director | 普通株式 | 購入 | 15,000 | $21.51 |
| 2013-12-11 | GREY, MICHAEL G | Director | 普通株式 | 購入 | 7,500 | $17.33 |
| 2013-12-09 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 2,900 | $69.76 |
| 2013-12-09 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 84 | $17.86 |
| 2013-12-09 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 3,750 | $14.39 |
| 2013-12-09 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 13,026 | $69.55 |
| 2013-12-09 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 9,192 | $21.51 |
| 2013-12-09 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 84 | $0.00 |
| 2013-12-09 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 3,125 | $0.00 |
| 2013-12-09 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 625 | $0.00 |
| 2013-12-09 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 9,192 | $0.00 |
| 2013-12-09 | LEWIS, ALAN | Director | 普通株式 | 購入 | 15,000 | $26.49 |
| 2013-12-09 | LEWIS, ALAN | Director | 普通株式 | 購入 | 7,500 | $38.59 |
| 2013-12-09 | LEWIS, ALAN | Director | 普通株式 | 売却 | 22,500 | $69.91 |
| 2013-12-09 | LEWIS, ALAN | Director | ストックオプション | 売却 | 15,000 | $0.00 |
| 2013-12-09 | LEWIS, ALAN | Director | ストックオプション | 売却 | 7,500 | $0.00 |
| 2013-12-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $12.99 |
| 2013-12-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $69.70 |
| 2013-12-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2013-12-02 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 9,000 | $39.06 |
| 2013-12-02 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | ストックオプション | 売却 | 9,000 | $0.00 |
| 2013-12-02 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 9,000 | $70.14 |
| 2013-11-20 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 8 | $65.89 |
| 2013-11-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $0.00 |
| 2013-11-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $12.99 |
| 2013-11-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $0.00 |
| 2013-11-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $62.36 |
| 2013-11-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $12.99 |
| 2013-11-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2013-11-01 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 99 | $63.16 |
| 2013-10-31 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 99 | $27.91 |
| 2013-10-31 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $0.00 |
| 2013-10-31 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $62.72 |
| 2013-10-31 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $12.99 |
| 2013-10-30 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 5 | $65.75 |
| 2013-10-30 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 4 | $66.48 |
| 2013-10-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $0.00 |
| 2013-10-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 2,000 | $12.99 |
| 2013-10-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $67.73 |
| 2013-10-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $66.76 |
| 2013-10-07 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 6 | $74.84 |
| 2013-10-04 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 5 | $74.07 |
| 2013-09-19 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 10,000 | $11.05 |
| 2013-09-19 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 10,000 | $0.00 |
| 2013-09-19 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 10,000 | $80.19 |
| 2013-09-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $73.08 |
| 2013-09-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 2,000 | $12.99 |
| 2013-09-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $0.00 |
| 2013-09-10 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 7 | $70.30 |
| 2013-09-10 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 8 | $70.06 |
| 2013-09-09 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 20,000 | $21.51 |
| 2013-09-09 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 20,000 | $0.00 |
| 2013-09-09 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 20,000 | $73.00 |
| 2013-09-05 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 10,000 | $70.00 |
| 2013-09-05 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 10,000 | $0.00 |
| 2013-09-05 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 10,000 | $11.05 |
| 2013-09-04 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | ストックオプション | 売却 | 9,000 | $0.00 |
| 2013-09-04 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 9,000 | $69.00 |
| 2013-09-04 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 9,000 | $39.06 |
| 2013-08-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $12.99 |
| 2013-08-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $64.36 |
| 2013-08-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $0.00 |
| 2013-07-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $0.00 |
| 2013-07-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $12.99 |
| 2013-07-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $63.70 |
| 2013-07-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 10,000 | $11.05 |
| 2013-07-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 10,000 | $60.00 |
| 2013-07-01 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 2,033 | $60.00 |
| 2013-07-01 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 2,033 | $59.56 |
| 2013-07-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 10,000 | $0.00 |
| 2013-06-19 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 9 | $58.85 |
| 2013-06-19 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 9 | $58.57 |
| 2013-06-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2013-06-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $12.99 |
| 2013-06-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 220,500 | $0.00 |
| 2013-06-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 220,500 | $0.00 |
| 2013-06-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $60.00 |
| 2013-06-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $58.68 |
| 2013-06-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $12.99 |
| 2013-06-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $0.00 |
| 2013-06-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $12.99 |
| 2013-06-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $60.72 |
| 2013-06-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $0.00 |
| 2013-06-03 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 493 | $58.34 |
| 2013-06-03 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 1,098 | $58.32 |
| 2013-05-31 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 413 | $62.70 |
| 2013-05-31 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 297 | $62.70 |
| 2013-05-31 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 3,000 | $12.99 |
| 2013-05-31 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $0.00 |
| 2013-05-29 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 4,184 | $64.46 |
| 2013-05-23 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,131 | $0.00 |
| 2013-05-23 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 8,710 | $67.16 |
| 2013-05-23 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,131 | $0.00 |
| 2013-05-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 938 | $14.39 |
| 2013-05-22 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 11,899 | $65.66 |
| 2013-05-22 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 10,000 | $11.05 |
| 2013-05-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 520 | $37.46 |
| 2013-05-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 812 | $26.49 |
| 2013-05-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 833 | $21.51 |
| 2013-05-22 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 10,000 | $0.00 |
| 2013-05-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 520 | $0.00 |
| 2013-05-22 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 812 | $0.00 |
| 2013-05-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 833 | $0.00 |
| 2013-05-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 938 | $0.00 |
| 2013-05-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 3,103 | $67.12 |
| 2013-05-21 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $64.14 |
| 2013-05-21 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 2,000 | $12.99 |
| 2013-05-17 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $64.01 |
| 2013-05-17 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $12.99 |
| 2013-05-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $64.65 |
| 2013-05-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2013-05-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $0.00 |
| 2013-05-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 2,000 | $12.99 |
| 2013-05-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $64.65 |
| 2013-05-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 37,800 | $0.00 |
| 2013-05-15 | HERON, ELAINE J | Director | 普通株式 | 購入 | 8,500 | $0.00 |
| 2013-05-15 | HERON, ELAINE J | Director | 普通株式 | 購入 | 3,400 | $0.00 |
| 2013-05-15 | BATE, KENNETH | Director | ストックオプション | 購入 | 8,500 | $0.00 |
| 2013-05-15 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 3,400 | $0.00 |
| 2013-05-15 | MEIER, RICHARD A | Director | ストックオプション | 購入 | 8,500 | $0.00 |
| 2013-05-15 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 15,600 | $0.00 |
| 2013-05-15 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 91,000 | $0.00 |
| 2013-05-15 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 13,200 | $0.00 |
| 2013-05-15 | BATE, KENNETH | Director | 普通株式 | 購入 | 3,400 | $ |
| 2013-05-15 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 3,400 | $0.00 |
| 2013-05-15 | LAWLIS, V BRYAN | Director | ストックオプション | 購入 | 8,500 | $0.00 |
| 2013-05-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $12.99 |
| 2013-05-15 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 8,400 | $0.00 |
| 2013-05-15 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 49,000 | $0.00 |
| 2013-05-15 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 8,400 | $0.00 |
| 2013-05-15 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 49,000 | $0.00 |
| 2013-05-15 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 2,200 | $0.00 |
| 2013-05-15 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 12,900 | $0.00 |
| 2013-05-15 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 12,000 | $0.00 |
| 2013-05-15 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 70,000 | $0.00 |
| 2013-05-15 | YOUNG, WILLIAM D | Director | 普通株式 | 購入 | 3,400 | $ |
| 2013-05-15 | YOUNG, WILLIAM D | Director | ストックオプション | 購入 | 8,500 | $0.00 |
| 2013-05-15 | LEWIS, ALAN | Director | 普通株式 | 購入 | 3,400 | $0.00 |
| 2013-05-15 | LEWIS, ALAN | Director | 普通株式 | 購入 | 8,500 | $0.00 |
| 2013-05-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $0.00 |
| 2013-05-15 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | ストックオプション | 売却 | 77,000 | $0.00 |
| 2013-05-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 220,500 | $0.00 |
| 2013-05-15 | LAPALME, PIERRE | Director | ストックオプション | 購入 | 8,500 | $0.00 |
| 2013-05-15 | LAPALME, PIERRE | Director | 普通株式 | 購入 | 3,400 | $0.00 |
| 2013-05-15 | GREY, MICHAEL G | Director | ストックオプション | 購入 | 8,500 | $0.00 |
| 2013-05-15 | GREY, MICHAEL G | Director | 普通株式 | 購入 | 3,400 | $0.00 |
| 2013-05-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $0.00 |
| 2013-05-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $68.55 |
| 2013-05-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 15,000 | $70.17 |
| 2013-05-14 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 20,000 | $21.51 |
| 2013-05-14 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 20,000 | $21.51 |
| 2013-05-14 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 20,000 | $21.51 |
| 2013-05-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 25,000 | $0.00 |
| 2013-05-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $70.74 |
| 2013-05-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $71.07 |
| 2013-05-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $71.08 |
| 2013-05-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $12.99 |
| 2013-05-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $12.99 |
| 2013-05-14 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 20,000 | $0.00 |
| 2013-05-14 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 20,000 | $70.00 |
| 2013-05-14 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 20,000 | $70.34 |
| 2013-05-14 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 3,500 | $21.51 |
| 2013-05-14 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 3,500 | $70.33 |
| 2013-05-14 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 3,500 | $21.51 |
| 2013-05-14 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 1,447 | $70.41 |
| 2013-05-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 15,000 | $0.00 |
| 2013-05-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 15,000 | $12.99 |
| 2013-05-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $0.00 |
| 2013-05-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $69.11 |
| 2013-05-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $69.11 |
| 2013-05-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $12.99 |
| 2013-05-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 3,000 | $12.99 |
| 2013-05-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $69.56 |
| 2013-05-13 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 2,590 | $69.29 |
| 2013-05-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 7,064 | $0.00 |
| 2013-05-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 7,064 | $0.00 |
| 2013-05-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $68.12 |
| 2013-05-13 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 1,248 | $69.26 |
| 2013-05-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2013-05-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 8,873 | $67.68 |
| 2013-05-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 8,742 | $67.68 |
| 2013-05-12 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 2,258 | $67.68 |
| 2013-05-12 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 817 | $67.68 |
| 2013-05-12 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 3,001 | $67.68 |
| 2013-05-12 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 752 | $67.68 |
| 2013-05-12 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 1,096 | $67.68 |
| 2013-05-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 800 | $67.48 |
| 2013-05-09 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 811 | $66.00 |
| 2013-05-08 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 3,131 | $65.32 |
| 2013-05-08 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 2,088 | $65.32 |
| 2013-05-08 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 1,664 | $65.32 |
| 2013-05-08 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 479 | $65.32 |
| 2013-05-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,479 | $65.32 |
| 2013-05-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $65.88 |
| 2013-05-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $0.00 |
| 2013-05-08 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 489 | $65.32 |
| 2013-05-08 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 1,305 | $65.32 |
| 2013-05-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $65.87 |
| 2013-05-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 3,000 | $12.99 |
| 2013-05-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $0.00 |
| 2013-05-03 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 5,854 | $67.19 |
| 2013-05-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2013-05-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $0.00 |
| 2013-05-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $67.26 |
| 2013-05-03 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 4,874 | $0.00 |
| 2013-05-03 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 3,562 | $0.00 |
| 2013-05-03 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 7,500 | $67.11 |
| 2013-05-03 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 7,500 | $21.51 |
| 2013-05-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $12.99 |
| 2013-05-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $67.21 |
| 2013-05-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 3,000 | $12.99 |
| 2013-05-03 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 2,292 | $0.00 |
| 2013-05-03 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 2,292 | $14.39 |
| 2013-05-03 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 20,000 | $0.00 |
| 2013-05-03 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 3,562 | $17.54 |
| 2013-05-03 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 20,000 | $67.00 |
| 2013-05-03 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 20,000 | $14.39 |
| 2013-05-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $0.00 |
| 2013-05-02 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 7,500 | $0.00 |
| 2013-05-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 2,000 | $12.99 |
| 2013-05-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $65.62 |
| 2013-05-02 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 4,457 | $65.48 |
| 2013-05-02 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 4,874 | $14.39 |
| 2013-05-02 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 4,874 | $65.35 |
| 2013-05-01 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | ストックオプション | 売却 | 28,000 | $0.00 |
| 2013-05-01 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 売却 | 28,000 | $64.42 |
| 2013-05-01 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 805 | $0.00 |
| 2013-05-01 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 805 | $0.00 |
| 2013-05-01 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 28,000 | $39.06 |
| 2013-05-01 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 797 | $64.52 |
| 2013-04-30 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 20,000 | $63.29 |
| 2013-04-30 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 858 | $23.21 |
| 2013-04-30 | FUCHS, HENRY J | EVP, Chief Medical Officer | ストックオプション | 売却 | 20,000 | $0.00 |
| 2013-04-30 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 20,000 | $11.05 |
| 2013-04-30 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 916 | $23.21 |
| 2013-04-30 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $63.74 |
| 2013-04-30 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 581 | $23.21 |
| 2013-04-30 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 797 | $23.20 |
| 2013-04-30 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 916 | $22.21 |
| 2013-04-30 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 805 | $23.21 |
| 2013-04-30 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 595 | $27.91 |
| 2013-04-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 937 | $0.00 |
| 2013-04-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 3,102 | $65.57 |
| 2013-04-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 520 | $37.46 |
| 2013-04-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 812 | $26.49 |
| 2013-04-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 833 | $21.51 |
| 2013-04-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 937 | $14.39 |
| 2013-04-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 520 | $0.00 |
| 2013-04-22 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 812 | $0.00 |
| 2013-04-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 833 | $0.00 |
| 2013-04-19 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 5,000 | $21.51 |
| 2013-04-19 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 5,000 | $0.00 |
| 2013-04-19 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 5,000 | $65.00 |
| 2013-04-10 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 20,000 | $14.39 |
| 2013-04-10 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 20,000 | $64.00 |
| 2013-04-10 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 20,000 | $0.00 |
| 2013-03-26 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 12,000 | $60.68 |
| 2013-03-26 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 12,000 | $0.00 |
| 2013-03-26 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 12,000 | $12.99 |
| 2013-03-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 3,103 | $60.21 |
| 2013-03-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 833 | $21.51 |
| 2013-03-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 812 | $26.49 |
| 2013-03-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 520 | $37.46 |
| 2013-03-22 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 812 | $0.00 |
| 2013-03-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 833 | $0.00 |
| 2013-03-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 938 | $0.00 |
| 2013-03-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 520 | $37.46 |
| 2013-03-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 938 | $14.39 |
| 2013-03-20 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 5 | $61.99 |
| 2013-03-20 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 4 | $61.43 |
| 2013-03-18 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 20,000 | $14.39 |
| 2013-03-18 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 7 | $61.38 |
| 2013-03-18 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 20,000 | $0.00 |
| 2013-03-18 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 20,000 | $61.02 |
| 2013-03-18 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 7 | $61.48 |
| 2013-03-06 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 15,000 | $60.61 |
| 2013-03-06 | GREY, MICHAEL G | Director | ストックオプション | 売却 | 15,000 | $0.00 |
| 2013-03-04 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 4,000 | $17.86 |
| 2013-03-04 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 4,000 | $0.00 |
| 2013-03-04 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 4,000 | $21.51 |
| 2013-03-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $12.99 |
| 2013-03-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $60.00 |
| 2013-03-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2013-03-04 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 4,000 | $60.18 |
| 2013-03-04 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 4,000 | $17.86 |
| 2013-03-04 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 4,000 | $60.00 |
| 2013-03-03 | GREY, MICHAEL G | Director | 普通株式 | 購入 | 15,000 | $14.39 |
| 2013-03-01 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 3,605 | $0.00 |
| 2013-03-01 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 688 | $38.59 |
| 2013-03-01 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 730 | $17.86 |
| 2013-03-01 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 3,605 | $14.39 |
| 2013-03-01 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 5,023 | $59.74 |
| 2013-03-01 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 2,015 | $59.81 |
| 2013-03-01 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 688 | $0.00 |
| 2013-03-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $59.14 |
| 2013-03-01 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 730 | $0.00 |
| 2013-03-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 1,908 | $59.61 |
| 2013-02-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $58.00 |
| 2013-02-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $12.99 |
| 2013-02-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2013-02-27 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 8,000 | $56.90 |
| 2013-02-27 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,500 | $56.46 |
| 2013-02-27 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 4,583 | $14.39 |
| 2013-02-27 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 3,417 | $0.00 |
| 2013-02-27 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 4,583 | $14.39 |
| 2013-02-27 | LEWIS, ALAN | Director | 普通株式 | 購入 | 7,500 | $38.59 |
| 2013-02-27 | LEWIS, ALAN | Director | 普通株式 | 購入 | 7,500 | $14.39 |
| 2013-02-27 | LEWIS, ALAN | Director | 普通株式 | 購入 | 7,500 | $21.51 |
| 2013-02-27 | LEWIS, ALAN | Director | 普通株式 | 売却 | 22,500 | $56.57 |
| 2013-02-27 | LEWIS, ALAN | Director | 普通株式 | 売却 | 7,500 | $0.00 |
| 2013-02-27 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 3,417 | $17.54 |
| 2013-02-26 | LAPALME, PIERRE | Director | ストックオプション | 売却 | 20,000 | $0.00 |
| 2013-02-26 | LAPALME, PIERRE | Director | ストックオプション | 売却 | 9,900 | $0.00 |
| 2013-02-26 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 29,900 | $55.34 |
| 2013-02-26 | LAPALME, PIERRE | Director | 普通株式 | 購入 | 20,000 | $11.15 |
| 2013-02-26 | LAPALME, PIERRE | Director | 普通株式 | 購入 | 9,900 | $8.47 |
| 2013-02-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 834 | $21.51 |
| 2013-02-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 520 | $37.46 |
| 2013-02-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 937 | $0.00 |
| 2013-02-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 812 | $26.49 |
| 2013-02-22 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 812 | $0.00 |
| 2013-02-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 937 | $14.39 |
| 2013-02-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 520 | $55.00 |
| 2013-02-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 834 | $0.00 |
| 2013-02-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 520 | $37.46 |
| 2013-02-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 2,583 | $55.26 |
| 2013-02-19 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 5,000 | $16.92 |
| 2013-02-19 | MEIER, RICHARD A | Director | 普通株式 | 売却 | 5,000 | $57.50 |
| 2013-02-19 | MEIER, RICHARD A | Director | ストックオプション | 売却 | 5,000 | $0.00 |
| 2013-02-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 2,000 | $12.99 |
| 2013-02-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $0.00 |
| 2013-02-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $55.77 |
| 2013-01-23 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $55.22 |
| 2013-01-22 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 3,000 | $0.00 |
| 2013-01-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 40,000 | $38.59 |
| 2013-01-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 939 | $14.39 |
| 2013-01-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 812 | $26.49 |
| 2013-01-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 833 | $21.51 |
| 2013-01-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 2,584 | $54.81 |
| 2013-01-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 44,165 | $55.00 |
| 2013-01-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 40,000 | $38.59 |
| 2013-01-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 4,165 | $37.46 |
| 2013-01-22 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 812 | $0.00 |
| 2013-01-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 939 | $0.00 |
| 2013-01-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 833 | $0.00 |
| 2013-01-22 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 19,575 | $17.54 |
| 2013-01-22 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 2,675 | $0.00 |
| 2013-01-22 | MEIER, RICHARD A | Director | 普通株式 | 売却 | 5,000 | $55.00 |
| 2013-01-22 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 5,000 | $16.92 |
| 2013-01-22 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 19,575 | $0.00 |
| 2013-01-22 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 19,575 | $55.00 |
| 2013-01-22 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 2,675 | $0.00 |
| 2013-01-22 | MEIER, RICHARD A | Director | ストックオプション | 売却 | 5,000 | $0.00 |
| 2013-01-22 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $55.00 |
| 2013-01-22 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 3,000 | $21.51 |
| 2013-01-22 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 3,000 | $55.00 |
| 2013-01-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 4,165 | $37.46 |
| 2013-01-18 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2013-01-18 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $54.00 |
| 2013-01-18 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $12.99 |
| 2013-01-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 3,000 | $12.99 |
| 2013-01-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $0.00 |
| 2013-01-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $52.24 |
| 2013-01-03 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 20,000 | $0.00 |
| 2013-01-03 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 20,000 | $17.54 |
| 2013-01-03 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 20,000 | $53.00 |
| 2013-01-02 | MEIER, RICHARD A | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2013-01-02 | MEIER, RICHARD A | Director | 普通株式 | 売却 | 5,000 | $52.50 |
| 2013-01-02 | MEIER, RICHARD A | Director | 普通株式 | 売却 | 5,000 | $50.00 |
| 2013-01-02 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 10,000 | $16.92 |
| 2012-12-31 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $48.62 |
| 2012-12-31 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $12.99 |
| 2012-12-31 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2012-12-27 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $0.00 |
| 2012-12-27 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $48.34 |
| 2012-12-27 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 4,000 | $12.99 |
| 2012-12-26 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 7,000 | $0.00 |
| 2012-12-26 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 7,000 | $12.99 |
| 2012-12-26 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 7,000 | $48.38 |
| 2012-12-24 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 6,000 | $48.38 |
| 2012-12-24 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 6,000 | $0.00 |
| 2012-12-24 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 6,000 | $12.99 |
| 2012-12-21 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $48.57 |
| 2012-12-21 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 3,000 | $12.99 |
| 2012-12-21 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 6,000 | $12.99 |
| 2012-12-21 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 6,000 | $48.57 |
| 2012-12-21 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $0.00 |
| 2012-12-21 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 6,000 | $0.00 |
| 2012-12-17 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 170 | $0.00 |
| 2012-12-17 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 170 | $17.86 |
| 2012-12-17 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 833 | $21.51 |
| 2012-12-17 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 833 | $0.00 |
| 2012-12-17 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 941 | $0.00 |
| 2012-12-17 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 812 | $0.00 |
| 2012-12-17 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 2,756 | $49.32 |
| 2012-12-17 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 812 | $26.49 |
| 2012-12-17 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 941 | $14.39 |
| 2012-12-13 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 7,659 | $49.11 |
| 2012-12-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2012-12-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $12.99 |
| 2012-12-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $50.00 |
| 2012-12-11 | MEIER, RICHARD A | Director | ストックオプション | 売却 | 5,000 | $0.00 |
| 2012-12-11 | MEIER, RICHARD A | Director | 普通株式 | 売却 | 5,000 | $49.71 |
| 2012-12-11 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 5,000 | $16.92 |
| 2012-12-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $0.00 |
| 2012-12-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 3,000 | $12.99 |
| 2012-12-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $48.03 |
| 2012-12-08 | BIOMARIN, PHARMACEUTICAL INC | 10% Owner | 普通株式 | 売却 | 5,000,000 | $ |
| 2012-12-08 | BIOMARIN, PHARMACEUTICAL INC | 10% Owner | 普通株式 | 購入 | 5,000,000 | $0.75 |
| 2012-12-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $0.00 |
| 2012-12-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 3,000 | $9.86 |
| 2012-12-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $47.04 |
| 2012-12-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $12.99 |
| 2012-12-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $0.00 |
| 2012-12-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $47.94 |
| 2012-11-29 | MEIER, RICHARD A | Director | ストックオプション | 売却 | 5,000 | $0.00 |
| 2012-11-29 | MEIER, RICHARD A | Director | 普通株式 | 売却 | 5,000 | $49.17 |
| 2012-11-29 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 5,000 | $16.92 |
| 2012-11-28 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 5,916 | $48.31 |
| 2012-11-28 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 2,500 | $0.00 |
| 2012-11-28 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 916 | $0.00 |
| 2012-11-28 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 2,500 | $14.39 |
| 2012-11-28 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 916 | $17.86 |
| 2012-11-28 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 2,500 | $21.51 |
| 2012-11-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 937 | $14.39 |
| 2012-11-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 812 | $0.00 |
| 2012-11-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 833 | $0.00 |
| 2012-11-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 2,665 | $48.92 |
| 2012-11-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 83 | $0.00 |
| 2012-11-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 937 | $0.00 |
| 2012-11-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 812 | $26.49 |
| 2012-11-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 83 | $17.86 |
| 2012-11-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 833 | $21.51 |
| 2012-11-19 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 7,363 | $0.00 |
| 2012-11-19 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 7,363 | $48.50 |
| 2012-11-19 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 7,363 | $17.54 |
| 2012-11-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 8,000 | $0.00 |
| 2012-11-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 8,000 | $12.99 |
| 2012-11-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 8,000 | $48.05 |
| 2012-11-15 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 5,500 | $14.39 |
| 2012-11-15 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 15,812 | $50.00 |
| 2012-11-15 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 20,000 | $0.00 |
| 2012-11-15 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 20,000 | $51.00 |
| 2012-11-15 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 20,000 | $17.54 |
| 2012-11-15 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 10,312 | $0.00 |
| 2012-11-15 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 5,500 | $0.00 |
| 2012-11-15 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 10,312 | $38.59 |
| 2012-11-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 4,000 | $12.99 |
| 2012-11-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $0.00 |
| 2012-11-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $48.50 |
| 2012-11-12 | HERON, ELAINE J | Director | 普通株式 | 売却 | 300 | $48.35 |
| 2012-11-12 | HERON, ELAINE J | Director | 普通株式 | 売却 | 1,575 | $48.32 |
| 2012-11-12 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 10,137 | $0.00 |
| 2012-11-12 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 10,137 | $48.63 |
| 2012-11-12 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 売却 | 265 | $48.11 |
| 2012-11-12 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 1,438 | $48.70 |
| 2012-11-12 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 10,137 | $17.54 |
| 2012-11-12 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 1,329 | $38.00 |
| 2012-11-09 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 45,000 | $17.33 |
| 2012-11-09 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 6,979 | $14.39 |
| 2012-11-09 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $48.42 |
| 2012-11-09 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 35,521 | $17.54 |
| 2012-11-09 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 35,521 | $0.00 |
| 2012-11-09 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 6,979 | $0.00 |
| 2012-11-09 | DAVIS, GEORGE ERIC | SVP, General Counsel | ストックオプション | 売却 | 45,000 | $0.00 |
| 2012-11-09 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 17,500 | $48.55 |
| 2012-11-09 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 50,000 | $48.55 |
| 2012-11-09 | HERON, ELAINE J | Director | 普通株式 | 売却 | 30,000 | $48.01 |
| 2012-11-09 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 20,000 | $48.00 |
| 2012-11-07 | LEWIS, ALAN | Director | 普通株式 | 購入 | 15,000 | $17.33 |
| 2012-11-07 | LEWIS, ALAN | Director | 普通株式 | 売却 | 15,000 | $46.80 |
| 2012-11-07 | LEWIS, ALAN | Director | 普通株式 | 売却 | 15,000 | $0.00 |
| 2012-11-07 | HERON, ELAINE J | Director | 普通株式 | 購入 | 30,000 | $7.46 |
| 2012-11-07 | HERON, ELAINE J | Director | 普通株式 | 購入 | 30,000 | $14.93 |
| 2012-11-07 | HERON, ELAINE J | Director | 普通株式 | 購入 | 15,000 | $17.33 |
| 2012-11-07 | HERON, ELAINE J | Director | 普通株式 | 購入 | 15,000 | $38.59 |
| 2012-11-07 | HERON, ELAINE J | Director | 普通株式 | 購入 | 15,000 | $14.39 |
| 2012-11-07 | HERON, ELAINE J | Director | 普通株式 | 売却 | 105,000 | $46.44 |
| 2012-11-07 | HERON, ELAINE J | Director | ストックオプション | 売却 | 30,000 | $0.00 |
| 2012-11-07 | HERON, ELAINE J | Director | 普通株式 | 売却 | 30,000 | $0.00 |
| 2012-11-07 | HERON, ELAINE J | Director | 普通株式 | 売却 | 15,000 | $0.00 |
| 2012-11-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $47.73 |
| 2012-11-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $47.00 |
| 2012-11-05 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 5,770 | $47.00 |
| 2012-11-05 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 14,230 | $47.00 |
| 2012-11-05 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 10,000 | $46.00 |
| 2012-11-05 | FUCHS, HENRY J | EVP, Chief Medical Officer | ストックオプション | 売却 | 10,000 | $0.00 |
| 2012-11-05 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 34,230 | $17.33 |
| 2012-11-05 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 5,500 | $47.50 |
| 2012-11-05 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 2,500 | $46.00 |
| 2012-11-05 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 8,000 | $0.00 |
| 2012-11-05 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 8,000 | $14.39 |
| 2012-11-05 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 25,770 | $0.00 |
| 2012-11-05 | BAFFI, ROBERT | EVP, Technical Operations | ストックオプション | 売却 | 34,230 | $0.00 |
| 2012-11-05 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 20,000 | $49.00 |
| 2012-11-05 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 25,770 | $17.54 |
| 2012-11-05 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 20,000 | $46.00 |
| 2012-11-05 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 10,000 | $11.05 |
| 2012-11-02 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 161 | $0.00 |
| 2012-11-02 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 161 | $0.00 |
| 2012-11-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 5,000 | $37.08 |
| 2012-11-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 5,000 | $11.05 |
| 2012-11-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2012-10-31 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 3,000 | $9.86 |
| 2012-10-31 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 3,000 | $0.00 |
| 2012-10-31 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 109 | $21.76 |
| 2012-10-31 | AJER, JEFFREY ROBERT | SVP, Chief Commercial Of | 普通株式 | 購入 | 265 | $21.76 |
| 2012-10-31 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $37.68 |
| 2012-10-31 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $38.81 |
| 2012-10-22 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 3,000 | $0.00 |
| 2012-10-22 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 3,000 | $9.86 |
| 2012-10-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 937 | $0.00 |
| 2012-10-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 83 | $0.00 |
| 2012-10-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 812 | $0.00 |
| 2012-10-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 2,665 | $41.86 |
| 2012-10-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 833 | $21.51 |
| 2012-10-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 937 | $14.39 |
| 2012-10-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 83 | $17.86 |
| 2012-10-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 833 | $0.00 |
| 2012-10-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 812 | $26.49 |
| 2012-10-22 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $41.86 |
| 2012-10-19 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $42.72 |
| 2012-10-16 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 20,000 | $17.33 |
| 2012-10-16 | BAFFI, ROBERT | EVP, Technical Operations | ストックオプション | 売却 | 20,000 | $0.00 |
| 2012-10-16 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 20,000 | $43.00 |
| 2012-10-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 3,000 | $0.00 |
| 2012-10-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 3,000 | $9.86 |
| 2012-10-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $41.32 |
| 2012-10-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 5,000 | $11.05 |
| 2012-10-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 5,000 | $39.75 |
| 2012-10-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2012-09-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 4,000 | $0.00 |
| 2012-09-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $40.20 |
| 2012-09-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 4,000 | $9.86 |
| 2012-09-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 937 | $14.39 |
| 2012-09-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 83 | $17.86 |
| 2012-09-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 812 | $26.49 |
| 2012-09-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 812 | $0.00 |
| 2012-09-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 2,665 | $40.48 |
| 2012-09-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 83 | $0.00 |
| 2012-09-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 937 | $0.00 |
| 2012-09-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 833 | $0.00 |
| 2012-09-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 833 | $21.51 |
| 2012-09-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 4,000 | $9.86 |
| 2012-09-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 4,000 | $9.86 |
| 2012-09-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 4,000 | $37.91 |
| 2012-09-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $38.62 |
| 2012-09-04 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 5,000 | $37.76 |
| 2012-09-04 | FUCHS, HENRY J | EVP, Chief Medical Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2012-09-04 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 5,000 | $11.05 |
| 2012-08-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 812 | $38.00 |
| 2012-08-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 83 | $17.86 |
| 2012-08-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 937 | $0.00 |
| 2012-08-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 833 | $0.00 |
| 2012-08-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 833 | $21.51 |
| 2012-08-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 1,853 | $37.90 |
| 2012-08-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 813 | $0.00 |
| 2012-08-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 83 | $0.00 |
| 2012-08-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 937 | $14.39 |
| 2012-08-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 812 | $26.49 |
| 2012-08-06 | LEWIS, ALAN | Director | 普通株式 | 購入 | 30,000 | $14.21 |
| 2012-08-06 | LEWIS, ALAN | Director | 普通株式 | 売却 | 40,000 | $37.57 |
| 2012-08-06 | LEWIS, ALAN | Director | 普通株式 | 売却 | 30,000 | $0.00 |
| 2012-08-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 5,000 | $11.05 |
| 2012-08-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 5,000 | $38.63 |
| 2012-08-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2012-07-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 813 | $0.00 |
| 2012-07-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 813 | $26.49 |
| 2012-07-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 83 | $17.86 |
| 2012-07-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 937 | $14.39 |
| 2012-07-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 833 | $21.51 |
| 2012-07-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 2,666 | $39.25 |
| 2012-07-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 83 | $0.00 |
| 2012-07-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 937 | $0.00 |
| 2012-07-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 833 | $0.00 |
| 2012-07-10 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 2,500 | $42.50 |
| 2012-07-10 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 2,500 | $14.39 |
| 2012-07-10 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 2,500 | $0.00 |
| 2012-07-02 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 10,000 | $40.00 |
| 2012-07-02 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 5,000 | $40.56 |
| 2012-07-02 | FUCHS, HENRY J | EVP, Chief Medical Officer | ストックオプション | 売却 | 15,000 | $0.00 |
| 2012-07-02 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 2,770 | $17.86 |
| 2012-07-02 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 2,770 | $40.00 |
| 2012-07-02 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 2,770 | $0.00 |
| 2012-07-02 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 売却 | 95,345 | $40.00 |
| 2012-07-02 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 購入 | 95,345 | $17.54 |
| 2012-07-02 | ASELAGE, STEVE | EVP, Chief Business Officer | ストックオプション | 売却 | 95,345 | $17.54 |
| 2012-07-02 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 15,000 | $11.05 |
| 2012-06-27 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 812 | $38.00 |
| 2012-06-27 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 812 | $26.49 |
| 2012-06-27 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 812 | $26.49 |
| 2012-06-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 83 | $17.86 |
| 2012-06-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 833 | $21.51 |
| 2012-06-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 937 | $14.39 |
| 2012-06-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 83 | $17.86 |
| 2012-06-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 937 | $14.39 |
| 2012-06-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 833 | $21.51 |
| 2012-06-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 1,853 | $36.83 |
| 2012-06-06 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 1,250 | $0.00 |
| 2012-06-06 | WOOD, MARK | VP, Human Resources | 譲渡制限付株式ユニット | 売却 | 1,250 | $0.00 |
| 2012-06-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2012-06-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 5,000 | $11.05 |
| 2012-06-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 5,000 | $35.02 |
| 2012-05-31 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 8,000 | $6.46 |
| 2012-05-31 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 2,000 | $6.46 |
| 2012-05-31 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 2,000 | $6.46 |
| 2012-05-31 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 8,000 | $6.46 |
| 2012-05-29 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | ストックオプション | 購入 | 125,000 | $0.00 |
| 2012-05-29 | SPIEGELMAN, DANIEL K | EVP, Chief Financial Officer | 普通株式 | 購入 | 33,000 | $ |
| 2012-05-22 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 150 | $0.00 |
| 2012-05-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 83 | $17.86 |
| 2012-05-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 937 | $14.39 |
| 2012-05-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 833 | $21.51 |
| 2012-05-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 813 | $26.49 |
| 2012-05-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 2,666 | $38.01 |
| 2012-05-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 83 | $17.86 |
| 2012-05-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 937 | $14.39 |
| 2012-05-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 833 | $21.51 |
| 2012-05-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 813 | $26.49 |
| 2012-05-22 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 56 | $37.98 |
| 2012-05-22 | MUELLER, BRIAN | VP, Corporate Controller | 譲渡制限付株式ユニット | 購入 | 150 | $0.00 |
| 2012-05-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $38.53 |
| 2012-05-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 10,000 | $9.86 |
| 2012-05-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 5,000 | $9.86 |
| 2012-05-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $9.86 |
| 2012-05-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $9.86 |
| 2012-05-16 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $38.47 |
| 2012-05-15 | LAWLIS, V BRYAN | Director | ストックオプション | 売却 | 6,400 | $14.39 |
| 2012-05-15 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 購入 | 10,000 | $17.33 |
| 2012-05-15 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 売却 | 10,000 | $38.64 |
| 2012-05-15 | ASELAGE, STEVE | EVP, Chief Business Officer | ストックオプション | 売却 | 10,000 | $17.33 |
| 2012-05-15 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 1,741 | $38.64 |
| 2012-05-15 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 6,400 | $14.39 |
| 2012-05-15 | LAWLIS, V BRYAN | Director | 普通株式 | 売却 | 8,900 | $38.51 |
| 2012-05-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 15,000 | $9.86 |
| 2012-05-14 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 25,250 | $38.09 |
| 2012-05-14 | COOPER, JEFFREY H | SVP, Chief Financial Officer | ストックオプション | 売却 | 15,000 | $26.49 |
| 2012-05-14 | COOPER, JEFFREY H | SVP, Chief Financial Officer | ストックオプション | 売却 | 6,500 | $21.51 |
| 2012-05-14 | COOPER, JEFFREY H | SVP, Chief Financial Officer | ストックオプション | 売却 | 3,750 | $14.39 |
| 2012-05-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 15,000 | $9.86 |
| 2012-05-14 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 15,000 | $26.49 |
| 2012-05-14 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 6,500 | $21.51 |
| 2012-05-14 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 3,750 | $14.39 |
| 2012-05-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 15,000 | $38.13 |
| 2012-05-12 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 750 | $0.00 |
| 2012-05-12 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 812 | $0.00 |
| 2012-05-12 | MUELLER, BRIAN | VP, Corporate Controller | 譲渡制限付株式ユニット | 購入 | 812 | $0.00 |
| 2012-05-12 | MUELLER, BRIAN | VP, Corporate Controller | 譲渡制限付株式ユニット | 購入 | 750 | $0.00 |
| 2012-05-11 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $6.46 |
| 2012-05-11 | DAVIS, GEORGE ERIC | SVP, General Counsel | ストックオプション | 売却 | 40,000 | $14.39 |
| 2012-05-11 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 購入 | 16,875 | $14.39 |
| 2012-05-11 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 売却 | 16,875 | $37.98 |
| 2012-05-11 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 2,437 | $17.86 |
| 2012-05-11 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 500 | $38.13 |
| 2012-05-11 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $38.08 |
| 2012-05-11 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 20,000 | $38.01 |
| 2012-05-11 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 15,000 | $9.86 |
| 2012-05-11 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 5,000 | $38.08 |
| 2012-05-11 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 2,437 | $38.00 |
| 2012-05-11 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 2,437 | $26.49 |
| 2012-05-11 | ASELAGE, STEVE | EVP, Chief Business Officer | ストックオプション | 売却 | 4,655 | $17.54 |
| 2012-05-11 | ASELAGE, STEVE | EVP, Chief Business Officer | ストックオプション | 売却 | 16,875 | $0.00 |
| 2012-05-11 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 売却 | 4,630 | $37.07 |
| 2012-05-11 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 売却 | 4,655 | $37.98 |
| 2012-05-11 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 購入 | 4,655 | $17.54 |
| 2012-05-11 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 15,000 | $9.86 |
| 2012-05-11 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 10,000 | $6.46 |
| 2012-05-11 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 2,309 | $37.07 |
| 2012-05-11 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 40,000 | $14.39 |
| 2012-05-11 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 35,000 | $37.94 |
| 2012-05-08 | DAVIS, GEORGE ERIC | SVP, General Counsel | ストックオプション | 購入 | 32,500 | $0.00 |
| 2012-05-08 | WOOD, MARK | VP, Human Resources | ストックオプション | 購入 | 25,000 | $0.00 |
| 2012-05-08 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 13,000 | $ |
| 2012-05-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 15,000 | $0.00 |
| 2012-05-08 | MUELLER, BRIAN | VP, Corporate Controller | ストックオプション | 売却 | 4,291 | $0.00 |
| 2012-05-08 | MUELLER, BRIAN | VP, Corporate Controller | ストックオプション | 売却 | 10,000 | $0.00 |
| 2012-05-08 | MUELLER, BRIAN | VP, Corporate Controller | ストックオプション | 購入 | 11,800 | $0.00 |
| 2012-05-08 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 15,708 | $37.50 |
| 2012-05-08 | LEWIS, ALAN | Director | ストックオプション | 購入 | 8,500 | $0.00 |
| 2012-05-08 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 375 | $17.89 |
| 2012-05-08 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 625 | $17.89 |
| 2012-05-08 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 4,291 | $17.33 |
| 2012-05-08 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 417 | $17.54 |
| 2012-05-08 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 3,400 | $ |
| 2012-05-08 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 10,000 | $11.74 |
| 2012-05-08 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 4,720 | $ |
| 2012-05-08 | BATE, KENNETH | Director | 普通株式 | 購入 | 3,400 | $ |
| 2012-05-08 | BATE, KENNETH | Director | ストックオプション | 購入 | 8,500 | $0.00 |
| 2012-05-08 | YOUNG, WILLIAM D | Director | 普通株式 | 購入 | 3,400 | $ |
| 2012-05-08 | YOUNG, WILLIAM D | Director | ストックオプション | 購入 | 8,500 | $0.00 |
| 2012-05-08 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 3,400 | $ |
| 2012-05-08 | MEIER, RICHARD A | Director | ストックオプション | 購入 | 8,500 | $0.00 |
| 2012-05-08 | BAFFI, ROBERT | EVP, Technical Operations | ストックオプション | 購入 | 40,000 | $0.00 |
| 2012-05-08 | MUELLER, BRIAN | VP, Corporate Controller | ストックオプション | 売却 | 675 | $37.50 |
| 2012-05-08 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 24,000 | $ |
| 2012-05-08 | FUCHS, HENRY J | EVP, Chief Medical Officer | ストックオプション | 購入 | 60,000 | $0.00 |
| 2012-05-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 15,000 | $9.86 |
| 2012-05-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 15,000 | $36.52 |
| 2012-05-08 | MUELLER, BRIAN | VP, Corporate Controller | ストックオプション | 売却 | 625 | $37.50 |
| 2012-05-08 | MUELLER, BRIAN | VP, Corporate Controller | ストックオプション | 売却 | 375 | $0.00 |
| 2012-05-08 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 購入 | 16,000 | $ |
| 2012-05-08 | MUELLER, BRIAN | VP, Corporate Controller | ストックオプション | 売却 | 417 | $0.00 |
| 2012-05-08 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 10,000 | $ |
| 2012-05-08 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 16,000 | $ |
| 2012-05-08 | LAPALME, PIERRE | Director | ストックオプション | 購入 | 8,500 | $0.00 |
| 2012-05-08 | LAPALME, PIERRE | Director | 普通株式 | 購入 | 3,400 | $ |
| 2012-05-08 | LEWIS, ALAN | Director | 普通株式 | 購入 | 3,400 | $ |
| 2012-05-08 | ASELAGE, STEVE | EVP, Chief Business Officer | ストックオプション | 購入 | 40,000 | $0.00 |
| 2012-05-08 | HERON, ELAINE J | Director | 普通株式 | 購入 | 3,400 | $ |
| 2012-05-08 | HERON, ELAINE J | Director | ストックオプション | 購入 | 8,500 | $0.00 |
| 2012-05-08 | GREY, MICHAEL G | Director | 普通株式 | 購入 | 3,400 | $ |
| 2012-05-08 | GREY, MICHAEL G | Director | ストックオプション | 購入 | 8,500 | $0.00 |
| 2012-05-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 56,000 | $ |
| 2012-05-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 購入 | 140,000 | $0.00 |
| 2012-05-08 | LAWLIS, V BRYAN | Director | ストックオプション | 購入 | 8,500 | $0.00 |
| 2012-05-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $35.96 |
| 2012-05-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $9.86 |
| 2012-05-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2012-05-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $36.00 |
| 2012-05-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 10,000 | $0.00 |
| 2012-05-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $9.86 |
| 2012-05-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $36.68 |
| 2012-05-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 10,000 | $0.00 |
| 2012-05-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $9.86 |
| 2012-05-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 10,000 | $0.00 |
| 2012-05-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $35.72 |
| 2012-05-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $9.86 |
| 2012-05-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 20,000 | $0.00 |
| 2012-05-01 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 920 | $0.00 |
| 2012-05-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 5,000 | $11.05 |
| 2012-05-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 20,000 | $35.00 |
| 2012-05-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 5,000 | $34.99 |
| 2012-05-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 20,000 | $9.86 |
| 2012-05-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2012-05-01 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 920 | $0.00 |
| 2012-04-30 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 920 | $19.35 |
| 2012-04-30 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 1,098 | $19.35 |
| 2012-04-30 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 購入 | 1,006 | $19.35 |
| 2012-04-30 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 985 | $19.35 |
| 2012-04-30 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 480 | $27.91 |
| 2012-04-30 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 980 | $19.35 |
| 2012-04-30 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,098 | $19.35 |
| 2012-04-30 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 664 | $19.35 |
| 2012-04-27 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 20,000 | $35.03 |
| 2012-04-27 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 20,000 | $9.86 |
| 2012-04-27 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 20,000 | $0.00 |
| 2012-04-27 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $34.66 |
| 2012-04-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 83 | $17.86 |
| 2012-04-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 937 | $14.39 |
| 2012-04-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 833 | $21.51 |
| 2012-04-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 83 | $17.86 |
| 2012-04-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 937 | $14.39 |
| 2012-04-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 833 | $21.51 |
| 2012-04-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 1,853 | $34.54 |
| 2012-04-20 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 7,691 | $35.00 |
| 2012-04-02 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 5,000 | $11.05 |
| 2012-04-02 | FUCHS, HENRY J | EVP, Chief Medical Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2012-04-02 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 5,000 | $34.08 |
| 2012-03-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 84 | $17.86 |
| 2012-03-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 938 | $14.39 |
| 2012-03-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 833 | $21.51 |
| 2012-03-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 938 | $14.39 |
| 2012-03-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 84 | $17.86 |
| 2012-03-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 1,855 | $35.65 |
| 2012-03-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 833 | $21.51 |
| 2012-03-09 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 15,000 | $6.47 |
| 2012-03-09 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 15,000 | $34.46 |
| 2012-03-09 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 15,000 | $0.00 |
| 2012-03-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $35.00 |
| 2012-02-29 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $36.26 |
| 2012-02-28 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 20,000 | $36.01 |
| 2012-02-28 | LAPALME, PIERRE | Director | ストックオプション | 売却 | 20,000 | $0.00 |
| 2012-02-28 | LAPALME, PIERRE | Director | 普通株式 | 購入 | 20,000 | $8.47 |
| 2012-02-27 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $35.94 |
| 2012-02-24 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 41,964 | $17.33 |
| 2012-02-24 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 5,000 | $11.74 |
| 2012-02-24 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 25,000 | $21.51 |
| 2012-02-24 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $35.20 |
| 2012-02-24 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 4,864 | $17.54 |
| 2012-02-24 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 8,708 | $17.86 |
| 2012-02-24 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 41,964 | $17.33 |
| 2012-02-24 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 4,864 | $17.54 |
| 2012-02-24 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 83,036 | $35.07 |
| 2012-02-24 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 25,000 | $21.51 |
| 2012-02-24 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 2,500 | $14.39 |
| 2012-02-24 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 8,708 | $17.86 |
| 2012-02-24 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 2,500 | $14.39 |
| 2012-02-24 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 16,313 | $6.13 |
| 2012-02-24 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 75,000 | $11.74 |
| 2012-02-24 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 91,313 | $34.84 |
| 2012-02-24 | BAFFI, ROBERT | EVP, Technical Operations | ストックオプション | 売却 | 16,313 | $6.13 |
| 2012-02-24 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 75,000 | $11.74 |
| 2012-02-24 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 売却 | 5,000 | $35.07 |
| 2012-02-24 | MUELLER, BRIAN | VP, Corporate Controller | ストックオプション | 売却 | 5,000 | $0.00 |
| 2012-02-23 | GREY, MICHAEL G | Director | 普通株式 | 購入 | 30,000 | $35.36 |
| 2012-02-23 | GREY, MICHAEL G | Director | 普通株式 | 購入 | 30,000 | $16.92 |
| 2012-02-23 | GREY, MICHAEL G | Director | ストックオプション | 購入 | 30,000 | $0.00 |
| 2012-02-23 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $35.31 |
| 2012-02-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 834 | $21.51 |
| 2012-02-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 834 | $21.51 |
| 2012-02-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 1,854 | $35.14 |
| 2012-02-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 83 | $17.86 |
| 2012-02-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 937 | $14.39 |
| 2012-02-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 83 | $17.86 |
| 2012-02-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 937 | $14.39 |
| 2012-02-02 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 6,500 | $26.49 |
| 2012-02-02 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 6,500 | $38.00 |
| 2012-02-02 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 6,500 | $26.49 |
| 2012-01-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 833 | $21.51 |
| 2012-01-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 83 | $17.86 |
| 2012-01-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 938 | $14.39 |
| 2012-01-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 1,854 | $34.96 |
| 2012-01-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 833 | $21.51 |
| 2012-01-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 938 | $14.39 |
| 2012-01-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 83 | $17.86 |
| 2012-01-03 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 2,500 | $11.05 |
| 2012-01-03 | FUCHS, HENRY J | EVP, Chief Medical Officer | ストックオプション | 売却 | 2,500 | $0.00 |
| 2012-01-03 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 2,500 | $34.75 |
| 2012-01-03 | COOPER, JEFFREY H | SVP, Chief Financial Officer | ストックオプション | 売却 | 2,500 | $0.00 |
| 2012-01-03 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 2,500 | $34.75 |
| 2012-01-03 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 2,500 | $14.39 |
| 2011-12-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 84 | $17.86 |
| 2011-12-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 833 | $21.51 |
| 2011-12-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 1,854 | $33.79 |
| 2011-12-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 84 | $17.86 |
| 2011-12-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 833 | $21.51 |
| 2011-12-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 937 | $14.39 |
| 2011-12-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 937 | $14.39 |
| 2011-11-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 938 | $14.39 |
| 2011-11-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 83 | $17.86 |
| 2011-11-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 1,855 | $32.18 |
| 2011-11-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 834 | $21.51 |
| 2011-11-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 834 | $21.51 |
| 2011-11-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 83 | $17.86 |
| 2011-11-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 938 | $14.39 |
| 2011-11-14 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 333 | $0.00 |
| 2011-11-14 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 333 | $0.00 |
| 2011-11-01 | COOPER, JEFFREY H | SVP, Chief Financial Officer | ストックオプション | 売却 | 2,500 | $0.00 |
| 2011-11-01 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 260 | $33.23 |
| 2011-11-01 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 2,500 | $33.26 |
| 2011-11-01 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 2,500 | $14.39 |
| 2011-10-31 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 156 | $13.23 |
| 2011-10-31 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 260 | $13.23 |
| 2011-10-31 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 228 | $13.23 |
| 2011-10-28 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 購入 | 16,875 | $14.39 |
| 2011-10-28 | ASELAGE, STEVE | EVP, Chief Business Officer | ストックオプション | 売却 | 16,875 | $0.00 |
| 2011-10-28 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 売却 | 16,875 | $35.00 |
| 2011-10-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 937 | $14.39 |
| 2011-10-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 83 | $17.86 |
| 2011-10-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 937 | $14.39 |
| 2011-10-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 833 | $21.51 |
| 2011-10-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 83 | $17.86 |
| 2011-10-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 833 | $21.51 |
| 2011-10-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 1,853 | $33.32 |
| 2011-10-10 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 18,379 | $17.54 |
| 2011-10-10 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 18,379 | $34.00 |
| 2011-10-10 | COOPER, JEFFREY H | SVP, Chief Financial Officer | ストックオプション | 売却 | 18,379 | $0.00 |
| 2011-10-03 | FUCHS, HENRY J | EVP, Chief Medical Officer | ストックオプション | 売却 | 2,500 | $0.00 |
| 2011-10-03 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 2,500 | $11.05 |
| 2011-10-03 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 2,500 | $31.00 |
| 2011-09-28 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 18,379 | $32.00 |
| 2011-09-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $32.00 |
| 2011-09-28 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 18,379 | $17.54 |
| 2011-09-28 | COOPER, JEFFREY H | SVP, Chief Financial Officer | ストックオプション | 売却 | 18,379 | $0.00 |
| 2011-09-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 938 | $14.39 |
| 2011-09-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 83 | $17.86 |
| 2011-09-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 938 | $14.39 |
| 2011-09-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 833 | $21.51 |
| 2011-09-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 1,854 | $29.92 |
| 2011-09-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 83 | $17.86 |
| 2011-09-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 833 | $21.51 |
| 2011-09-01 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 2,500 | $29.41 |
| 2011-09-01 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 2,500 | $14.39 |
| 2011-09-01 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 2,500 | $0.00 |
| 2011-08-31 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 834 | $21.51 |
| 2011-08-31 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 834 | $30.00 |
| 2011-08-31 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 834 | $21.51 |
| 2011-08-30 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 2,000 | $6.46 |
| 2011-08-30 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 2,000 | $0.00 |
| 2011-08-30 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $29.01 |
| 2011-08-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 937 | $14.39 |
| 2011-08-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 83 | $17.86 |
| 2011-08-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 937 | $14.39 |
| 2011-08-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 83 | $17.86 |
| 2011-08-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 1,020 | $27.03 |
| 2011-08-19 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 2,000 | $0.00 |
| 2011-08-19 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $26.75 |
| 2011-08-19 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 2,000 | $6.46 |
| 2011-08-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 3,000 | $0.00 |
| 2011-08-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 3,000 | $6.46 |
| 2011-08-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $27.10 |
| 2011-08-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $30.30 |
| 2011-08-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $30.23 |
| 2011-08-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 4,000 | $6.46 |
| 2011-08-02 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 18,687 | $0.00 |
| 2011-08-02 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 18,687 | $30.55 |
| 2011-08-02 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 18,687 | $6.13 |
| 2011-08-02 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 18,036 | $0.00 |
| 2011-08-02 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 18,036 | $30.47 |
| 2011-08-02 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 18,036 | $17.33 |
| 2011-08-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 4,000 | $0.00 |
| 2011-07-29 | DAVIS, GEORGE ERIC | SVP, General Counsel | ストックオプション | 売却 | 3,800 | $0.00 |
| 2011-07-29 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 3,800 | $31.00 |
| 2011-07-29 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 3,800 | $11.74 |
| 2011-07-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 84 | $17.86 |
| 2011-07-22 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 3,800 | $11.74 |
| 2011-07-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 938 | $14.39 |
| 2011-07-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 833 | $21.51 |
| 2011-07-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 1,855 | $30.29 |
| 2011-07-22 | DAVIS, GEORGE ERIC | SVP, General Counsel | ストックオプション | 売却 | 3,800 | $0.00 |
| 2011-07-22 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 3,800 | $30.50 |
| 2011-07-22 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 833 | $21.51 |
| 2011-07-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 938 | $14.39 |
| 2011-07-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 84 | $17.86 |
| 2011-07-14 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 5,000 | $11.05 |
| 2011-07-14 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 18,378 | $30.00 |
| 2011-07-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $30.00 |
| 2011-07-14 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 18,378 | $17.54 |
| 2011-07-14 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 10,833 | $0.00 |
| 2011-07-14 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 10,833 | $30.00 |
| 2011-07-14 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 10,833 | $21.51 |
| 2011-07-14 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 5,000 | $30.00 |
| 2011-07-14 | FUCHS, HENRY J | EVP, Chief Medical Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2011-07-14 | COOPER, JEFFREY H | SVP, Chief Financial Officer | ストックオプション | 売却 | 18,378 | $0.00 |
| 2011-07-01 | COOPER, JEFFREY H | SVP, Chief Financial Officer | ストックオプション | 売却 | 2,500 | $0.00 |
| 2011-07-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 2,500 | $11.05 |
| 2011-07-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 2,500 | $27.68 |
| 2011-07-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | ストックオプション | 売却 | 2,500 | $0.00 |
| 2011-07-01 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 2,500 | $14.39 |
| 2011-07-01 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 2,500 | $27.50 |
| 2011-06-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 371 | $25.56 |
| 2011-06-22 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 937 | $0.00 |
| 2011-06-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 1,645 | $25.93 |
| 2011-06-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 83 | $17.86 |
| 2011-06-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 625 | $17.33 |
| 2011-06-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 937 | $14.39 |
| 2011-06-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 1,000 | $0.00 |
| 2011-06-22 | WOOD, MARK | VP, Human Resources | 譲渡制限付株式ユニット | 売却 | 1,000 | $0.00 |
| 2011-06-22 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 625 | $0.00 |
| 2011-06-22 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 83 | $0.00 |
| 2011-06-07 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 2,000 | $0.00 |
| 2011-06-07 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 2,000 | $0.00 |
| 2011-06-07 | BAFFI, ROBERT | EVP, Technical Operations | 譲渡制限付株式ユニット | 売却 | 2,000 | $0.00 |
| 2011-06-07 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 1,500 | $0.00 |
| 2011-06-07 | DAVIS, GEORGE ERIC | SVP, General Counsel | 譲渡制限付株式ユニット | 売却 | 1,500 | $0.00 |
| 2011-06-07 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 譲渡制限付株式ユニット | 売却 | 2,000 | $0.00 |
| 2011-06-07 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 購入 | 2,500 | $0.00 |
| 2011-06-07 | ASELAGE, STEVE | EVP, Chief Business Officer | 譲渡制限付株式ユニット | 売却 | 2,500 | $0.00 |
| 2011-06-07 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 456 | $27.46 |
| 2011-06-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $0.00 |
| 2011-06-06 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $27.39 |
| 2011-06-06 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 1,250 | $0.00 |
| 2011-06-06 | WOOD, MARK | VP, Human Resources | 譲渡制限付株式ユニット | 売却 | 1,250 | $0.00 |
| 2011-05-31 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 3,160 | $ |
| 2011-05-31 | DAVIS, GEORGE ERIC | SVP, General Counsel | ストックオプション | 売却 | 3,800 | $0.00 |
| 2011-05-31 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 710 | $28.00 |
| 2011-05-31 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 3,800 | $28.50 |
| 2011-05-31 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 3,800 | $11.74 |
| 2011-05-31 | MUELLER, BRIAN | VP, Corporate Controller | ストックオプション | 購入 | 23,700 | $0.00 |
| 2011-05-27 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 290 | $28.00 |
| 2011-05-26 | COOPER, JEFFREY H | SVP, Chief Financial Officer | ストックオプション | 売却 | 17,500 | $0.00 |
| 2011-05-26 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 3,800 | $11.74 |
| 2011-05-26 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 3,800 | $27.50 |
| 2011-05-26 | DAVIS, GEORGE ERIC | SVP, General Counsel | ストックオプション | 売却 | 3,800 | $0.00 |
| 2011-05-26 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 17,500 | $27.50 |
| 2011-05-26 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 17,500 | $14.39 |
| 2011-05-26 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 購入 | 40,512 | $17.33 |
| 2011-05-26 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 売却 | 40,512 | $27.00 |
| 2011-05-26 | ASELAGE, STEVE | EVP, Chief Business Officer | ストックオプション | 売却 | 40,512 | $0.00 |
| 2011-05-25 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 購入 | 9,177 | $17.33 |
| 2011-05-25 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 売却 | 9,177 | $27.00 |
| 2011-05-25 | ASELAGE, STEVE | EVP, Chief Business Officer | ストックオプション | 売却 | 9,177 | $0.00 |
| 2011-05-25 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $26.94 |
| 2011-05-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 625 | $17.33 |
| 2011-05-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 708 | $26.00 |
| 2011-05-24 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 83 | $0.00 |
| 2011-05-24 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 625 | $0.00 |
| 2011-05-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 83 | $17.86 |
| 2011-05-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 938 | $14.39 |
| 2011-05-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 938 | $25.66 |
| 2011-05-23 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 938 | $0.00 |
| 2011-05-20 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 2,000 | $0.00 |
| 2011-05-20 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 2,000 | $0.00 |
| 2011-05-20 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 譲渡制限付株式ユニット | 売却 | 2,000 | $0.00 |
| 2011-05-20 | BAFFI, ROBERT | EVP, Technical Operations | 譲渡制限付株式ユニット | 売却 | 2,000 | $0.00 |
| 2011-05-20 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 7,500 | $0.00 |
| 2011-05-20 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 譲渡制限付株式ユニット | 売却 | 7,500 | $0.00 |
| 2011-05-20 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 1,750 | $0.00 |
| 2011-05-20 | DAVIS, GEORGE ERIC | SVP, General Counsel | 譲渡制限付株式ユニット | 売却 | 1,750 | $0.00 |
| 2011-05-20 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 購入 | 2,500 | $0.00 |
| 2011-05-20 | ASELAGE, STEVE | EVP, Chief Business Officer | 譲渡制限付株式ユニット | 売却 | 2,500 | $0.00 |
| 2011-05-13 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 1,032 | $26.68 |
| 2011-05-12 | LEWIS, ALAN | Director | 普通株式 | 購入 | 2,500 | $ |
| 2011-05-12 | MUELLER, BRIAN | VP, Corporate Controller | 譲渡制限付株式ユニット | 購入 | 750 | $0.00 |
| 2011-05-12 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 750 | $0.00 |
| 2011-05-12 | MUELLER, BRIAN | VP, Corporate Controller | 譲渡制限付株式ユニット | 購入 | 812 | $0.00 |
| 2011-05-12 | BATE, KENNETH | Director | 普通株式 | 購入 | 1,875 | $ |
| 2011-05-12 | BATE, KENNETH | Director | ストックオプション | 購入 | 11,250 | $0.00 |
| 2011-05-12 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 6,000 | $ |
| 2011-05-12 | LEWIS, ALAN | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2011-05-12 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 2,500 | $ |
| 2011-05-12 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 812 | $0.00 |
| 2011-05-12 | WOOD, MARK | VP, Human Resources | ストックオプション | 購入 | 39,000 | $0.00 |
| 2011-05-12 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 10,000 | $ |
| 2011-05-12 | BAFFI, ROBERT | EVP, Technical Operations | ストックオプション | 購入 | 80,000 | $0.00 |
| 2011-05-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 36,000 | $ |
| 2011-05-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 購入 | 280,000 | $0.00 |
| 2011-05-12 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 購入 | 10,000 | $ |
| 2011-05-12 | ASELAGE, STEVE | EVP, Chief Business Officer | ストックオプション | 購入 | 80,000 | $0.00 |
| 2011-05-12 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 12,000 | $ |
| 2011-05-12 | FUCHS, HENRY J | EVP, Chief Medical Officer | ストックオプション | 購入 | 84,000 | $0.00 |
| 2011-05-12 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 7,500 | $ |
| 2011-05-12 | COOPER, JEFFREY H | SVP, Chief Financial Officer | ストックオプション | 購入 | 60,000 | $0.00 |
| 2011-05-12 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 8,500 | $ |
| 2011-05-12 | DAVIS, GEORGE ERIC | SVP, General Counsel | ストックオプション | 購入 | 65,000 | $0.00 |
| 2011-05-12 | GREY, MICHAEL G | Director | 普通株式 | 購入 | 2,500 | $ |
| 2011-05-12 | GREY, MICHAEL G | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2011-05-12 | LAPALME, PIERRE | Director | 普通株式 | 購入 | 2,500 | $ |
| 2011-05-12 | LAPALME, PIERRE | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2011-05-12 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 2,500 | $ |
| 2011-05-12 | MEIER, RICHARD A | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2011-05-12 | LAWLIS, V BRYAN | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2011-05-12 | YOUNG, WILLIAM D | Director | 普通株式 | 購入 | 1,875 | $ |
| 2011-05-12 | YOUNG, WILLIAM D | Director | ストックオプション | 購入 | 11,250 | $0.00 |
| 2011-05-12 | HERON, ELAINE J | Director | 普通株式 | 購入 | 2,500 | $ |
| 2011-05-12 | HERON, ELAINE J | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2011-05-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 400 | $25.87 |
| 2011-05-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 200 | $25.64 |
| 2011-05-04 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 1,447 | $0.00 |
| 2011-05-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 1,000 | $0.00 |
| 2011-05-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,700 | $26.30 |
| 2011-05-04 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 1,447 | $0.00 |
| 2011-05-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $9.86 |
| 2011-05-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $25.84 |
| 2011-05-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $27.11 |
| 2011-05-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 3,000 | $9.86 |
| 2011-05-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $26.68 |
| 2011-05-03 | ASELAGE, STEVE | EVP, Chief Business Officer | ストックオプション | 売却 | 10,311 | $0.00 |
| 2011-05-03 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 売却 | 10,311 | $27.15 |
| 2011-05-03 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 購入 | 10,311 | $17.33 |
| 2011-05-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 3,000 | $0.00 |
| 2011-05-02 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 1,530 | $27.09 |
| 2011-04-29 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,826 | $11.64 |
| 2011-04-29 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 1,530 | $11.64 |
| 2011-04-29 | MUELLER, BRIAN | VP, Corporate Controller | 普通株式 | 購入 | 1,501 | $11.64 |
| 2011-04-29 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 購入 | 1,597 | $11.64 |
| 2011-04-29 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 1,620 | $13.23 |
| 2011-04-29 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 1,447 | $11.64 |
| 2011-04-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 1,566 | $11.64 |
| 2011-04-25 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 937 | $0.00 |
| 2011-04-25 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 84 | $17.86 |
| 2011-04-25 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 83 | $0.00 |
| 2011-04-25 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 1,646 | $26.35 |
| 2011-04-25 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 937 | $14.39 |
| 2011-04-25 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 625 | $17.33 |
| 2011-04-25 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 625 | $0.00 |
| 2011-04-20 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 5,000 | $11.05 |
| 2011-04-20 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 8,165 | $27.00 |
| 2011-04-20 | FUCHS, HENRY J | EVP, Chief Medical Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2011-04-20 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 5,000 | $27.00 |
| 2011-04-13 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 625 | $17.33 |
| 2011-04-13 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 83 | $0.00 |
| 2011-04-13 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 625 | $0.00 |
| 2011-04-13 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 3,800 | $11.74 |
| 2011-04-13 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 3,800 | $26.50 |
| 2011-04-13 | DAVIS, GEORGE ERIC | SVP, General Counsel | ストックオプション | 売却 | 3,800 | $0.00 |
| 2011-04-13 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 708 | $26.00 |
| 2011-04-13 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 83 | $17.86 |
| 2011-04-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 2,500 | $11.05 |
| 2011-04-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 2,500 | $25.45 |
| 2011-04-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | ストックオプション | 売却 | 2,500 | $0.00 |
| 2011-03-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 938 | $14.39 |
| 2011-03-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 938 | $23.42 |
| 2011-03-22 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 938 | $0.00 |
| 2011-03-09 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 6,000 | $24.49 |
| 2011-03-09 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 6,000 | $11.74 |
| 2011-03-09 | DAVIS, GEORGE ERIC | SVP, General Counsel | ストックオプション | 売却 | 6,000 | $0.00 |
| 2011-03-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 834 | $11.05 |
| 2011-03-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | ストックオプション | 売却 | 834 | $0.00 |
| 2011-03-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 834 | $24.18 |
| 2011-02-24 | LAPALME, PIERRE | Director | 普通株式 | 購入 | 15,000 | $5.92 |
| 2011-02-24 | LAPALME, PIERRE | Director | ストックオプション | 売却 | 15,000 | $0.00 |
| 2011-02-24 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 15,000 | $24.94 |
| 2011-02-23 | LAPALME, PIERRE | Director | ストックオプション | 売却 | 100 | $0.00 |
| 2011-02-23 | LAPALME, PIERRE | Director | 普通株式 | 購入 | 100 | $8.47 |
| 2011-02-23 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 100 | $26.00 |
| 2011-02-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 1,645 | $26.34 |
| 2011-02-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 83 | $17.86 |
| 2011-02-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 625 | $17.33 |
| 2011-02-22 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 937 | $0.00 |
| 2011-02-22 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 625 | $0.00 |
| 2011-02-22 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 83 | $0.00 |
| 2011-02-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 937 | $14.39 |
| 2011-02-01 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 1,250 | $0.00 |
| 2011-02-01 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 1,334 | $26.00 |
| 2011-02-01 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 84 | $0.00 |
| 2011-02-01 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 1,250 | $17.33 |
| 2011-02-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | ストックオプション | 売却 | 833 | $0.00 |
| 2011-02-01 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 84 | $14.39 |
| 2011-02-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 833 | $25.76 |
| 2011-02-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 833 | $11.05 |
| 2011-01-24 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 938 | $0.00 |
| 2011-01-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 938 | $25.73 |
| 2011-01-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 938 | $14.39 |
| 2011-01-18 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,500 | $26.58 |
| 2011-01-03 | FUCHS, HENRY J | EVP, Chief Medical Officer | ストックオプション | 売却 | 833 | $0.00 |
| 2011-01-03 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 833 | $26.99 |
| 2011-01-03 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 833 | $11.05 |
| 2010-12-22 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 625 | $0.00 |
| 2010-12-22 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 937 | $0.00 |
| 2010-12-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 2,479 | $28.21 |
| 2010-12-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 83 | $17.86 |
| 2010-12-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 834 | $17.54 |
| 2010-12-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 625 | $17.33 |
| 2010-12-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 937 | $14.39 |
| 2010-12-22 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 83 | $0.00 |
| 2010-12-20 | FUCHS, HENRY J | EVP, Chief Medical Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2010-12-20 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 5,000 | $28.00 |
| 2010-12-20 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 5,000 | $11.05 |
| 2010-12-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $6.46 |
| 2010-12-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 1,000 | $0.00 |
| 2010-12-13 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $27.43 |
| 2010-12-06 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 2,000 | $6.46 |
| 2010-12-06 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 2,000 | $0.00 |
| 2010-12-06 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 1,000 | $0.00 |
| 2010-12-06 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $27.17 |
| 2010-12-06 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $27.17 |
| 2010-12-06 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $6.46 |
| 2010-12-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 834 | $27.08 |
| 2010-12-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | ストックオプション | 売却 | 834 | $0.00 |
| 2010-12-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 834 | $11.05 |
| 2010-11-24 | COOPER, JEFFREY H | SVP, Chief Financial Officer | ストックオプション | 売却 | 11,250 | $0.00 |
| 2010-11-24 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 11,250 | $27.50 |
| 2010-11-24 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 11,250 | $14.39 |
| 2010-11-24 | DAVIS, GEORGE ERIC | SVP, General Counsel | ストックオプション | 売却 | 5,000 | $0.00 |
| 2010-11-24 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 5,000 | $27.50 |
| 2010-11-24 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 5,000 | $11.74 |
| 2010-11-23 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $27.02 |
| 2010-11-23 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $6.46 |
| 2010-11-23 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 1,000 | $0.00 |
| 2010-11-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 83 | $17.86 |
| 2010-11-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 938 | $14.39 |
| 2010-11-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 2,479 | $26.60 |
| 2010-11-22 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 938 | $0.00 |
| 2010-11-22 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 625 | $0.00 |
| 2010-11-22 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 833 | $0.00 |
| 2010-11-22 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 83 | $0.00 |
| 2010-11-22 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 834 | $0.00 |
| 2010-11-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 833 | $17.54 |
| 2010-11-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 625 | $17.33 |
| 2010-11-18 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 売却 | 31,375 | $25.87 |
| 2010-11-18 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $25.99 |
| 2010-11-18 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 購入 | 31,375 | $14.39 |
| 2010-11-18 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $6.46 |
| 2010-11-18 | ASELAGE, STEVE | EVP, Chief Business Officer | ストックオプション | 売却 | 31,375 | $0.00 |
| 2010-11-17 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 購入 | 8,000 | $25.75 |
| 2010-11-17 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 購入 | 500 | $14.39 |
| 2010-11-17 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 売却 | 500 | $25.80 |
| 2010-11-17 | ASELAGE, STEVE | EVP, Chief Business Officer | ストックオプション | 売却 | 500 | $0.00 |
| 2010-11-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $25.78 |
| 2010-11-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 1,000 | $0.00 |
| 2010-11-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 2,000 | $6.46 |
| 2010-11-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 2,000 | $0.00 |
| 2010-11-04 | DAVIS, GEORGE ERIC | SVP, General Counsel | ストックオプション | 売却 | 10,000 | $0.00 |
| 2010-11-04 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 10,000 | $11.74 |
| 2010-11-04 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 10,000 | $25.83 |
| 2010-11-04 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 371 | $25.90 |
| 2010-11-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 4,000 | $0.00 |
| 2010-11-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 4,000 | $6.46 |
| 2010-11-03 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 2,000 | $25.24 |
| 2010-11-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $25.46 |
| 2010-11-02 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 473 | $0.00 |
| 2010-11-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $25.64 |
| 2010-11-02 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 473 | $0.00 |
| 2010-11-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 2,000 | $0.00 |
| 2010-11-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 2,000 | $6.46 |
| 2010-11-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,500 | $25.65 |
| 2010-11-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | ストックオプション | 売却 | 833 | $0.00 |
| 2010-11-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 1,602 | $25.75 |
| 2010-11-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 833 | $11.05 |
| 2010-11-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 833 | $25.76 |
| 2010-10-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 19,635 | $25.00 |
| 2010-10-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 324 | $11.64 |
| 2010-10-29 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 15,000 | $17.33 |
| 2010-10-29 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 473 | $11.64 |
| 2010-10-29 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 20,000 | $17.54 |
| 2010-10-29 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 1,750 | $17.86 |
| 2010-10-29 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 購入 | 294 | $11.64 |
| 2010-10-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 28,750 | $11.74 |
| 2010-10-29 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 371 | $11.64 |
| 2010-10-29 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 1,602 | $13.23 |
| 2010-10-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | ストックオプション | 売却 | 28,750 | $0.00 |
| 2010-10-29 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 36,750 | $26.00 |
| 2010-10-29 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 15,000 | $0.00 |
| 2010-10-29 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 20,000 | $0.00 |
| 2010-10-29 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 1,750 | $0.00 |
| 2010-10-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 9,115 | $26.00 |
| 2010-10-25 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 15,209 | $24.00 |
| 2010-10-25 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 1,459 | $5.15 |
| 2010-10-25 | COOPER, JEFFREY H | SVP, Chief Financial Officer | ストックオプション | 購入 | 13,750 | $0.00 |
| 2010-10-25 | COOPER, JEFFREY H | SVP, Chief Financial Officer | ストックオプション | 購入 | 1,459 | $0.00 |
| 2010-10-25 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 13,750 | $6.13 |
| 2010-10-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 937 | $14.39 |
| 2010-10-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 937 | $23.52 |
| 2010-10-22 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 937 | $0.00 |
| 2010-10-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | ストックオプション | 売却 | 833 | $0.00 |
| 2010-10-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 833 | $11.05 |
| 2010-10-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 833 | $22.30 |
| 2010-09-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 938 | $22.92 |
| 2010-09-22 | BATE, KENNETH | Director | ストックオプション | 購入 | 30,000 | $22.70 |
| 2010-09-22 | YOUNG, WILLIAM D | Director | ストックオプション | 購入 | 30,000 | $22.70 |
| 2010-09-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 938 | $14.39 |
| 2010-09-22 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 938 | $0.00 |
| 2010-09-13 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 6,000 | $22.85 |
| 2010-09-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $6.46 |
| 2010-09-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 1,000 | $0.00 |
| 2010-09-08 | ASELAGE, STEVE | EVP, Chief Business Officer | ストックオプション | 売却 | 35,000 | $0.00 |
| 2010-09-08 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 売却 | 35,000 | $22.00 |
| 2010-09-08 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 購入 | 35,000 | $11.74 |
| 2010-09-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $22.22 |
| 2010-09-07 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 937 | $21.51 |
| 2010-09-07 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 937 | $0.00 |
| 2010-09-07 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 937 | $14.39 |
| 2010-09-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $20.89 |
| 2010-09-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | ストックオプション | 売却 | 834 | $0.00 |
| 2010-09-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 834 | $20.88 |
| 2010-09-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $21.00 |
| 2010-09-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 834 | $11.05 |
| 2010-08-30 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 3,000 | $6.46 |
| 2010-08-30 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 3,000 | $0.00 |
| 2010-08-30 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $20.71 |
| 2010-08-27 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 3,000 | $0.00 |
| 2010-08-27 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $20.68 |
| 2010-08-27 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 3,000 | $6.46 |
| 2010-08-20 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 5,657 | $20.62 |
| 2010-08-20 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 売却 | 10,000 | $20.54 |
| 2010-08-20 | DAVIS, GEORGE ERIC | SVP, General Counsel | ストックオプション | 売却 | 10,000 | $0.00 |
| 2010-08-20 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 10,000 | $11.74 |
| 2010-08-02 | FUCHS, HENRY J | EVP, Chief Medical Officer | ストックオプション | 購入 | 833 | $0.00 |
| 2010-08-02 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 833 | $11.05 |
| 2010-08-02 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 833 | $22.03 |
| 2010-07-26 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 1,875 | $14.39 |
| 2010-07-26 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 625 | $14.00 |
| 2010-07-26 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 1,875 | $21.00 |
| 2010-07-26 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 625 | $21.00 |
| 2010-07-26 | WOOD, MARK | VP, Human Resources | ストックオプション | 購入 | 1,875 | $0.00 |
| 2010-07-26 | WOOD, MARK | VP, Human Resources | ストックオプション | 購入 | 625 | $0.00 |
| 2010-07-23 | FUCHS, HENRY J | EVP, Chief Medical Officer | ストックオプション | 購入 | 833 | $0.00 |
| 2010-07-23 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 833 | $20.00 |
| 2010-07-23 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 833 | $11.05 |
| 2010-06-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 372 | $19.79 |
| 2010-06-08 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 470 | $18.87 |
| 2010-06-07 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 2,000 | $0.00 |
| 2010-06-07 | BAFFI, ROBERT | EVP, Technical Operations | 譲渡制限付株式ユニット | 売却 | 2,000 | $0.00 |
| 2010-06-07 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 購入 | 2,500 | $0.00 |
| 2010-06-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $0.00 |
| 2010-06-07 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 1,000 | $0.00 |
| 2010-06-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 譲渡制限付株式ユニット | 売却 | 5,000 | $0.00 |
| 2010-06-07 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 2,000 | $0.00 |
| 2010-06-07 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 譲渡制限付株式ユニット | 売却 | 2,000 | $0.00 |
| 2010-06-07 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 1,500 | $0.00 |
| 2010-06-07 | DAVIS, GEORGE ERIC | SVP, General Counsel | 譲渡制限付株式ユニット | 売却 | 1,500 | $0.00 |
| 2010-06-07 | ASELAGE, STEVE | EVP, Chief Business Officer | 譲渡制限付株式ユニット | 売却 | 2,500 | $0.00 |
| 2010-06-06 | WOOD, MARK | VP, Human Resources | 譲渡制限付株式ユニット | 売却 | 1,000 | $0.00 |
| 2010-06-06 | WOOD, MARK | VP, Human Resources | 譲渡制限付株式ユニット | 売却 | 1,250 | $0.00 |
| 2010-06-06 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 1,250 | $0.00 |
| 2010-06-02 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 834 | $11.05 |
| 2010-06-02 | FUCHS, HENRY J | EVP, Chief Medical Officer | ストックオプション | 購入 | 834 | $0.00 |
| 2010-06-02 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 834 | $20.00 |
| 2010-05-30 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 1,502 | $11.64 |
| 2010-05-22 | ASELAGE, STEVE | EVP, Chief Business Officer | 譲渡制限付株式ユニット | 売却 | 2,500 | $0.00 |
| 2010-05-22 | BAFFI, ROBERT | EVP, Technical Operations | 譲渡制限付株式ユニット | 売却 | 2,000 | $0.00 |
| 2010-05-22 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 2,000 | $0.00 |
| 2010-05-22 | DAVIS, GEORGE ERIC | SVP, General Counsel | 譲渡制限付株式ユニット | 売却 | 1,750 | $0.00 |
| 2010-05-22 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 1,750 | $0.00 |
| 2010-05-22 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 譲渡制限付株式ユニット | 売却 | 2,000 | $0.00 |
| 2010-05-22 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 7,500 | $0.00 |
| 2010-05-22 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 購入 | 2,500 | $0.00 |
| 2010-05-22 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 2,000 | $0.00 |
| 2010-05-22 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 譲渡制限付株式ユニット | 売却 | 7,500 | $0.00 |
| 2010-05-13 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 546 | $21.75 |
| 2010-05-12 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 購入 | 11,200 | $ |
| 2010-05-12 | LAWLIS, V BRYAN | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2010-05-12 | GREY, MICHAEL G | Director | 普通株式 | 購入 | 2,500 | $ |
| 2010-05-12 | GREY, MICHAEL G | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2010-05-12 | HERON, ELAINE J | Director | 普通株式 | 購入 | 2,500 | $ |
| 2010-05-12 | HERON, ELAINE J | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2010-05-12 | LAPALME, PIERRE | Director | 普通株式 | 購入 | 2,500 | $ |
| 2010-05-12 | LAPALME, PIERRE | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2010-05-12 | ASELAGE, STEVE | EVP, Chief Business Officer | ストックオプション | 購入 | 84,000 | $0.00 |
| 2010-05-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 36,000 | $ |
| 2010-05-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 購入 | 280,000 | $0.00 |
| 2010-05-12 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 11,000 | $ |
| 2010-05-12 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 2,500 | $ |
| 2010-05-12 | MEIER, RICHARD A | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2010-05-12 | FUCHS, HENRY J | EVP, Chief Medical Officer | ストックオプション | 購入 | 82,000 | $0.00 |
| 2010-05-12 | LEWIS, ALAN | Director | 普通株式 | 購入 | 2,500 | $ |
| 2010-05-12 | LEWIS, ALAN | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2010-05-12 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 10,700 | $ |
| 2010-05-12 | BAFFI, ROBERT | EVP, Technical Operations | ストックオプション | 購入 | 80,000 | $0.00 |
| 2010-05-12 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 2,500 | $ |
| 2010-05-12 | WOOD, MARK | VP, Human Resources | ストックオプション | 購入 | 40,000 | $0.00 |
| 2010-05-12 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 938 | $14.39 |
| 2010-05-12 | WOOD, MARK | VP, Human Resources | ストックオプション | 購入 | 938 | $0.00 |
| 2010-05-12 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 8,400 | $ |
| 2010-05-12 | DAVIS, GEORGE ERIC | SVP, General Counsel | ストックオプション | 購入 | 63,000 | $0.00 |
| 2010-05-12 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 8,400 | $ |
| 2010-05-12 | COOPER, JEFFREY H | SVP, Chief Financial Officer | ストックオプション | 購入 | 63,000 | $0.00 |
| 2010-05-12 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 5,300 | $ |
| 2010-05-12 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 938 | $21.41 |
| 2010-05-06 | WOOD, MARK | VP, Human Resources | ストックオプション | 購入 | 313 | $0.00 |
| 2010-05-06 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 313 | $21.03 |
| 2010-05-06 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 313 | $14.00 |
| 2010-05-05 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 1,353 | $0.00 |
| 2010-05-05 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 1,353 | $0.00 |
| 2010-05-04 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 876 | $0.00 |
| 2010-05-04 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 876 | $0.00 |
| 2010-05-03 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 833 | $11.05 |
| 2010-05-03 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 833 | $22.82 |
| 2010-05-03 | FUCHS, HENRY J | EVP, Chief Medical Officer | ストックオプション | 購入 | 833 | $0.00 |
| 2010-05-03 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 1,442 | $22.79 |
| 2010-04-30 | DAVIS, GEORGE ERIC | SVP, General Counsel | 普通株式 | 購入 | 1,456 | $11.64 |
| 2010-04-30 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 1,353 | $11.64 |
| 2010-04-30 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,827 | $11.64 |
| 2010-04-30 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 購入 | 1,532 | $11.64 |
| 2010-04-30 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 1,442 | $13.23 |
| 2010-04-12 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 937 | $23.81 |
| 2010-04-12 | WOOD, MARK | VP, Human Resources | ストックオプション | 購入 | 937 | $0.00 |
| 2010-04-12 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 937 | $14.39 |
| 2010-04-05 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 312 | $14.00 |
| 2010-04-05 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 312 | $24.63 |
| 2010-04-05 | WOOD, MARK | VP, Human Resources | ストックオプション | 購入 | 312 | $0.00 |
| 2010-04-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 売却 | 5,833 | $24.00 |
| 2010-04-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | ストックオプション | 購入 | 5,833 | $0.00 |
| 2010-04-01 | FUCHS, HENRY J | EVP, Chief Medical Officer | 普通株式 | 購入 | 5,833 | $11.05 |
| 2010-03-12 | WOOD, MARK | VP, Human Resources | ストックオプション | 購入 | 938 | $0.00 |
| 2010-03-12 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 938 | $22.17 |
| 2010-03-12 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 938 | $14.39 |
| 2010-03-10 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 購入 | 163,888 | $22.00 |
| 2010-03-10 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 163,888 | $22.52 |
| 2010-03-10 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 8,335 | $0.00 |
| 2010-03-10 | BAFFI, ROBERT | EVP, Technical Operations | 普通株式 | 売却 | 155,553 | $0.00 |
| 2010-03-08 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 購入 | 24,090 | $7.16 |
| 2010-03-08 | WOOD, MARK | VP, Human Resources | ストックオプション | 購入 | 313 | $0.00 |
| 2010-03-08 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 313 | $22.14 |
| 2010-03-08 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 313 | $14.00 |
| 2010-03-08 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 売却 | 24,090 | $22.11 |
| 2010-03-08 | KLEIN, JOSEPH III | Director | 普通株式 | 売却 | 10,000 | $22.12 |
| 2010-03-05 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 売却 | 6,416 | $21.95 |
| 2010-03-04 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 売却 | 5,000 | $21.50 |
| 2010-03-03 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 売却 | 10,000 | $21.00 |
| 2010-03-02 | WOOD, MARK | VP, Human Resources | ストックオプション | 購入 | 312 | $0.00 |
| 2010-03-02 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 1,249 | $21.00 |
| 2010-03-02 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 937 | $14.39 |
| 2010-03-02 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 312 | $14.00 |
| 2010-03-02 | ASELAGE, STEVE | EVP, Chief Business Officer | 普通株式 | 売却 | 10,000 | $21.00 |
| 2010-03-02 | WOOD, MARK | VP, Human Resources | ストックオプション | 購入 | 937 | $0.00 |
| 2010-02-26 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 800 | $20.08 |
| 2010-02-03 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 377 | $21.00 |
| 2010-02-03 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 377 | $11.74 |
| 2010-02-03 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 377 | $0.00 |
| 2010-01-26 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,500 | $19.75 |
| 2010-01-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 144 | $0.00 |
| 2010-01-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 144 | $21.05 |
| 2010-01-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 144 | $11.74 |
| 2010-01-19 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 7,499 | $14.39 |
| 2010-01-19 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 7,499 | $0.00 |
| 2010-01-19 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 3,750 | $14.00 |
| 2010-01-19 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 6,250 | $11.74 |
| 2010-01-19 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,500 | $20.89 |
| 2010-01-19 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 17,499 | $21.00 |
| 2010-01-19 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 6,250 | $0.00 |
| 2010-01-19 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 3,750 | $0.00 |
| 2009-12-22 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,500 | $18.83 |
| 2009-12-02 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 購入 | 5,000 | $8.05 |
| 2009-12-02 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 購入 | 9,000 | $7.84 |
| 2009-12-02 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 購入 | 7,000 | $6.13 |
| 2009-12-02 | DAVIS, GEORGE ERIC | VP, General Counsel | ストックオプション | 売却 | 5,000 | $0.00 |
| 2009-12-02 | DAVIS, GEORGE ERIC | VP, General Counsel | ストックオプション | 売却 | 7,000 | $0.00 |
| 2009-12-02 | DAVIS, GEORGE ERIC | VP, General Counsel | ストックオプション | 売却 | 9,000 | $0.00 |
| 2009-12-02 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 21,000 | $17.25 |
| 2009-08-28 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 177 | $0.00 |
| 2009-08-28 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 177 | $16.50 |
| 2009-08-28 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 177 | $6.13 |
| 2009-08-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 49 | $15.69 |
| 2009-08-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,951 | $15.95 |
| 2009-08-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $15.95 |
| 2009-07-08 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 456 | $13.89 |
| 2009-07-07 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 1,250 | $0.00 |
| 2009-07-07 | WOOD, MARK | VP, Human Resources | 譲渡制限付株式ユニット | 売却 | 1,250 | $0.00 |
| 2009-06-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 363 | $14.75 |
| 2009-06-22 | ASELAGE, STEVE | SVP, Chief Business Officer | 譲渡制限付株式ユニット | 売却 | 2,500 | $0.00 |
| 2009-06-22 | BAFFI, ROBERT | SVP, Technical Operations | 譲渡制限付株式ユニット | 売却 | 2,000 | $0.00 |
| 2009-06-22 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 譲渡制限付株式ユニット | 売却 | 7,500 | $0.00 |
| 2009-06-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 1,000 | $0.00 |
| 2009-06-22 | DAVIS, GEORGE ERIC | VP, General Counsel | 譲渡制限付株式ユニット | 売却 | 1,750 | $0.00 |
| 2009-06-22 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 購入 | 1,750 | $0.00 |
| 2009-06-22 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 購入 | 2,000 | $0.00 |
| 2009-06-22 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 7,500 | $0.00 |
| 2009-06-22 | WOOD, MARK | VP, Human Resources | 譲渡制限付株式ユニット | 売却 | 1,000 | $0.00 |
| 2009-06-22 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 譲渡制限付株式ユニット | 売却 | 2,000 | $0.00 |
| 2009-06-22 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 2,000 | $0.00 |
| 2009-06-22 | ASELAGE, STEVE | SVP, Chief Business Officer | 普通株式 | 購入 | 2,500 | $0.00 |
| 2009-06-19 | BIOMARIN, PHARMACEUTICAL INC | 10% Owner | 普通株式 | 売却 | 2,546,958 | $0.21 |
| 2009-06-18 | BIOMARIN, PHARMACEUTICAL INC | 10% Owner | 普通株式 | 売却 | 2,198,825 | $0.21 |
| 2009-06-17 | BIOMARIN, PHARMACEUTICAL INC | 10% Owner | 普通株式 | 売却 | 960,950 | $0.22 |
| 2009-06-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,500 | $14.52 |
| 2009-06-11 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 2,500 | $14.47 |
| 2009-06-07 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 譲渡制限付株式ユニット | 売却 | 2,000 | $0.00 |
| 2009-06-07 | BAFFI, ROBERT | SVP, Technical Operations | 譲渡制限付株式ユニット | 売却 | 2,000 | $0.00 |
| 2009-06-07 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 購入 | 2,000 | $ |
| 2009-06-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 譲渡制限付株式ユニット | 売却 | 5,000 | $0.00 |
| 2009-06-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $ |
| 2009-06-07 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 購入 | 1,500 | $ |
| 2009-06-07 | DAVIS, GEORGE ERIC | VP, General Counsel | 譲渡制限付株式ユニット | 売却 | 1,500 | $0.00 |
| 2009-06-07 | ASELAGE, STEVE | SVP, Chief Business Officer | 譲渡制限付株式ユニット | 売却 | 2,500 | $0.00 |
| 2009-06-07 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 2,000 | $ |
| 2009-06-07 | ASELAGE, STEVE | SVP, Chief Business Officer | 普通株式 | 購入 | 2,500 | $ |
| 2009-06-05 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 2,000 | $13.70 |
| 2009-05-22 | LAWLIS, V BRYAN | Director | 譲渡制限付株式ユニット | 売却 | 2,500 | $0.00 |
| 2009-05-22 | KLEIN, JOSEPH III | Director | 普通株式 | 購入 | 2,500 | $ |
| 2009-05-22 | KLEIN, JOSEPH III | Director | 譲渡制限付株式ユニット | 売却 | 2,500 | $0.00 |
| 2009-05-22 | HERON, ELAINE J | Director | 普通株式 | 購入 | 2,500 | $ |
| 2009-05-22 | HERON, ELAINE J | Director | 譲渡制限付株式ユニット | 売却 | 2,500 | $0.00 |
| 2009-05-22 | LEWIS, ALAN | Director | 普通株式 | 購入 | 2,500 | $ |
| 2009-05-22 | MEIER, RICHARD A | Director | 譲渡制限付株式ユニット | 売却 | 2,500 | $0.00 |
| 2009-05-22 | LAPALME, PIERRE | Director | 普通株式 | 購入 | 2,500 | $ |
| 2009-05-22 | LAPALME, PIERRE | Director | 譲渡制限付株式ユニット | 売却 | 2,500 | $0.00 |
| 2009-05-22 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 2,500 | $ |
| 2009-05-22 | GREY, MICHAEL G | Director | 普通株式 | 購入 | 2,500 | $ |
| 2009-05-22 | GREY, MICHAEL G | Director | 譲渡制限付株式ユニット | 売却 | 2,500 | $0.00 |
| 2009-05-22 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 2,500 | $ |
| 2009-05-22 | LEWIS, ALAN | Director | 譲渡制限付株式ユニット | 売却 | 2,500 | $0.00 |
| 2009-05-12 | DAVIS, GEORGE ERIC | VP, General Counsel | ストックオプション | 購入 | 55,000 | $0.00 |
| 2009-05-12 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 2,500 | $ |
| 2009-05-12 | MEIER, RICHARD A | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2009-05-12 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 6,000 | $ |
| 2009-05-12 | WOOD, MARK | VP, Human Resources | ストックオプション | 購入 | 45,000 | $0.00 |
| 2009-05-12 | LAWLIS, V BRYAN | Director | 普通株式 | 購入 | 2,500 | $ |
| 2009-05-12 | LAWLIS, V BRYAN | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2009-05-12 | KLEIN, JOSEPH III | Director | 普通株式 | 購入 | 2,500 | $ |
| 2009-05-12 | COOPER, JEFFREY H | SVP, Chief Financial Officer | ストックオプション | 購入 | 60,000 | $0.00 |
| 2009-05-12 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 8,000 | $ |
| 2009-05-12 | BAFFI, ROBERT | SVP, Technical Operations | ストックオプション | 購入 | 70,000 | $0.00 |
| 2009-05-12 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 購入 | 9,000 | $ |
| 2009-05-12 | LEWIS, ALAN | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2009-05-12 | LEWIS, ALAN | Director | 普通株式 | 購入 | 2,500 | $ |
| 2009-05-12 | ASELAGE, STEVE | SVP, Global Commercial Dev | ストックオプション | 購入 | 90,000 | $0.00 |
| 2009-05-12 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 購入 | 12,000 | $ |
| 2009-05-12 | KLEIN, JOSEPH III | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2009-05-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 購入 | 240,000 | $0.00 |
| 2009-05-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 32,000 | $ |
| 2009-05-12 | HERON, ELAINE J | Director | 普通株式 | 購入 | 2,500 | $ |
| 2009-05-12 | HERON, ELAINE J | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2009-05-12 | LAPALME, PIERRE | Director | 普通株式 | 購入 | 2,500 | $ |
| 2009-05-12 | LAPALME, PIERRE | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2009-05-12 | GREY, MICHAEL G | Director | 普通株式 | 購入 | 2,500 | $ |
| 2009-05-12 | GREY, MICHAEL G | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2009-05-12 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 購入 | 7,500 | $ |
| 2009-04-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 購入 | 1,524 | $10.93 |
| 2009-04-30 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 購入 | 1,523 | $10.93 |
| 2009-04-30 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,523 | $10.93 |
| 2009-04-30 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 購入 | 1,515 | $10.93 |
| 2009-04-30 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 1,456 | $10.93 |
| 2009-03-27 | BIOMARIN, PHARMACEUTICAL INC | 10% Owner | 普通株式 | 購入 | 10,173,120 | $ |
| 2009-03-27 | BIOMARIN, PHARMACEUTICAL INC | 10% Owner | 普通株式 | 売却 | 339,104 | $0.00 |
| 2009-03-13 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 1,000 | $11.45 |
| 2009-03-05 | KLEIN, JOSEPH III | Director | 普通株式 | 購入 | 5,000 | $10.07 |
| 2009-03-05 | BIENAIME, JEAN JACQUES | Chief Executive Officer | 普通株式 | 購入 | 1,000 | $10.04 |
| 2009-03-05 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 1,000 | $10.04 |
| 2009-03-03 | KLEIN, JOSEPH III | Director | 普通株式 | 購入 | 5,000 | $10.56 |
| 2009-03-03 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 1,000 | $10.75 |
| 2009-03-02 | FUCHS, HENRY J | Chief Medical Officer | ストックオプション | 購入 | 160,000 | $11.05 |
| 2009-03-02 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 7,897 | $11.70 |
| 2009-03-02 | KAKKIS, EMIL D | Chief Medical Officer | ストックオプション | 売却 | 7,897 | $0.00 |
| 2009-03-02 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 1,000 | $11.10 |
| 2009-03-02 | FUCHS, HENRY J | Chief Medical Officer | 普通株式 | 購入 | 20,000 | $ |
| 2009-03-02 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 購入 | 7,897 | $6.43 |
| 2009-02-24 | KLEIN, JOSEPH III | Director | 普通株式 | 購入 | 10,000 | $12.08 |
| 2009-02-03 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 購入 | 17,000 | $6.43 |
| 2009-02-03 | KAKKIS, EMIL D | Chief Medical Officer | ストックオプション | 売却 | 17,000 | $0.00 |
| 2009-02-03 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 17,000 | $19.14 |
| 2009-01-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 1 | $6.13 |
| 2009-01-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 1 | $19.05 |
| 2009-01-22 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 1 | $0.00 |
| 2009-01-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 177 | $6.13 |
| 2009-01-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 177 | $0.00 |
| 2009-01-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 177 | $19.30 |
| 2009-01-16 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 938 | $0.00 |
| 2009-01-16 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 1,563 | $11.74 |
| 2009-01-16 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 938 | $14.00 |
| 2009-01-16 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 2,501 | $21.00 |
| 2009-01-16 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 1,563 | $0.00 |
| 2009-01-02 | KAKKIS, EMIL D | Chief Medical officer | ストックオプション | 売却 | 10,417 | $0.00 |
| 2009-01-02 | KAKKIS, EMIL D | Chief Medical officer | 普通株式 | 購入 | 10,417 | $6.43 |
| 2009-01-02 | KAKKIS, EMIL D | Chief Medical officer | 普通株式 | 購入 | 6,583 | $6.13 |
| 2009-01-02 | KAKKIS, EMIL D | Chief Medical officer | ストックオプション | 売却 | 6,583 | $0.00 |
| 2009-01-02 | KAKKIS, EMIL D | Chief Medical officer | 普通株式 | 売却 | 17,000 | $17.57 |
| 2008-12-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 177 | $6.13 |
| 2008-12-22 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 177 | $0.00 |
| 2008-12-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 177 | $17.18 |
| 2008-12-17 | DAVIS, GEORGE ERIC | VP, General Counsel | ストックオプション | 購入 | 4,000 | $0.00 |
| 2008-12-17 | COOPER, JEFFREY H | SVP, Chief Financial Officer | ストックオプション | 購入 | 11,000 | $0.00 |
| 2008-12-17 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 購入 | 11,000 | $0.00 |
| 2008-12-17 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 購入 | 22,000 | $0.00 |
| 2008-12-17 | WOOD, MARK | VP, Human Resources | ストックオプション | 購入 | 4,000 | $0.00 |
| 2008-12-17 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 購入 | 11,000 | $0.00 |
| 2008-12-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 4,000 | $17.20 |
| 2008-12-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $17.00 |
| 2008-12-04 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 7,000 | $16.30 |
| 2008-12-03 | LAPALME, PIERRE | Director | 普通株式 | 購入 | 400 | $15.29 |
| 2008-12-03 | LAPALME, PIERRE | Director | 普通株式 | 購入 | 2,000 | $15.30 |
| 2008-12-01 | KAKKIS, EMIL D | CHIEF MEDICAL OFFICER | 普通株式 | 購入 | 17,000 | $6.13 |
| 2008-12-01 | KAKKIS, EMIL D | CHIEF MEDICAL OFFICER | 普通株式 | 売却 | 17,000 | $15.87 |
| 2008-12-01 | KAKKIS, EMIL D | CHIEF MEDICAL OFFICER | ストックオプション | 売却 | 17,000 | $0.00 |
| 2008-11-28 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 177 | $6.13 |
| 2008-11-28 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 177 | $0.00 |
| 2008-11-28 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 177 | $16.50 |
| 2008-11-25 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 75,000 | $15.98 |
| 2008-11-03 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 購入 | 16,000 | $6.13 |
| 2008-11-03 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 17,000 | $18.11 |
| 2008-11-03 | KAKKIS, EMIL D | Chief Medical Officer | ストックオプション | 売却 | 16,000 | $0.00 |
| 2008-10-31 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 購入 | 186 | $13.35 |
| 2008-10-31 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 購入 | 317 | $13.35 |
| 2008-10-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 177 | $20.22 |
| 2008-10-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 177 | $6.13 |
| 2008-10-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 177 | $0.00 |
| 2008-10-01 | KAKKIS, EMIL D | Chief Medical Officer | ストックオプション | 売却 | 18,000 | $0.00 |
| 2008-10-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 購入 | 18,000 | $6.13 |
| 2008-10-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 18,000 | $26.27 |
| 2008-09-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 177 | $6.13 |
| 2008-09-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 2,000 | $27.85 |
| 2008-09-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 468 | $28.81 |
| 2008-09-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 625 | $17.33 |
| 2008-09-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 833 | $17.54 |
| 2008-09-22 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 177 | $0.00 |
| 2008-09-22 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 521 | $0.00 |
| 2008-09-22 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 312 | $0.00 |
| 2008-09-22 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 833 | $0.00 |
| 2008-09-22 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 625 | $0.00 |
| 2008-09-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 312 | $14.00 |
| 2008-09-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 521 | $11.74 |
| 2008-09-02 | BAFFI, ROBERT | SVP, Technical Operations | ストックオプション | 売却 | 555 | $0.00 |
| 2008-09-02 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 購入 | 6,000 | $6.13 |
| 2008-09-02 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 18,000 | $30.19 |
| 2008-09-02 | KAKKIS, EMIL D | Chief Medical Officer | ストックオプション | 売却 | 6,000 | $0.00 |
| 2008-09-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 11,528 | $31.31 |
| 2008-09-02 | BAFFI, ROBERT | SVP, Technical Operations | ストックオプション | 売却 | 10,973 | $0.00 |
| 2008-09-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 購入 | 11,528 | $22.00 |
| 2008-08-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 625 | $17.33 |
| 2008-08-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 177 | $6.13 |
| 2008-08-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 834 | $17.54 |
| 2008-08-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 177 | $0.00 |
| 2008-08-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 2,469 | $26.10 |
| 2008-08-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 520 | $0.00 |
| 2008-08-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 520 | $11.74 |
| 2008-08-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 313 | $14.00 |
| 2008-08-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 625 | $0.00 |
| 2008-08-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 834 | $0.00 |
| 2008-08-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 313 | $0.00 |
| 2008-08-11 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 600 | $6.46 |
| 2008-08-11 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 600 | $0.00 |
| 2008-08-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 650 | $6.46 |
| 2008-08-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 650 | $0.00 |
| 2008-08-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Office | 普通株式 | 購入 | 500 | $6.46 |
| 2008-08-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Office | ストックオプション | 売却 | 500 | $0.00 |
| 2008-08-06 | BIENAIME, JEAN JACQUES | Director, Chief Executive Office | ストックオプション | 売却 | 600 | $0.00 |
| 2008-08-06 | BIENAIME, JEAN JACQUES | Director, Chief Executive Office | 普通株式 | 購入 | 600 | $6.46 |
| 2008-08-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 300 | $32.45 |
| 2008-08-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 2,000 | $32.46 |
| 2008-08-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 1,100 | $32.45 |
| 2008-08-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 4,500 | $32.45 |
| 2008-08-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 100 | $32.48 |
| 2008-08-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 100 | $32.53 |
| 2008-08-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 100 | $32.49 |
| 2008-08-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 100 | $32.42 |
| 2008-08-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 100 | $32.46 |
| 2008-08-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 300 | $32.47 |
| 2008-08-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 1,900 | $32.51 |
| 2008-08-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 1,000 | $32.51 |
| 2008-08-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 5,300 | $32.50 |
| 2008-08-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 100 | $32.51 |
| 2008-08-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 100 | $32.47 |
| 2008-08-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 100 | $32.34 |
| 2008-08-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 200 | $32.44 |
| 2008-08-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 200 | $32.43 |
| 2008-08-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 400 | $32.46 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 550 | $31.82 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 3,100 | $31.90 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $31.89 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $31.85 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $31.84 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 400 | $31.79 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $31.68 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 600 | $31.51 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 700 | $31.91 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 500 | $31.92 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $31.93 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,300 | $31.94 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 700 | $31.94 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 321 | $31.95 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 879 | $31.96 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $31.97 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 700 | $31.97 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,900 | $31.98 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $31.99 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 600 | $32.00 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 2,100 | $32.09 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 購入 | 19,528 | $22.00 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 28 | $31.04 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $31.05 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $31.08 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $31.15 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 500 | $31.24 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $31.30 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $31.33 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $31.35 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $31.36 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $31.37 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 66 | $31.46 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $31.47 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $31.49 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $31.51 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $31.56 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $31.57 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 234 | $31.63 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $31.65 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $31.69 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 600 | $31.78 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 250 | $31.91 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | ストックオプション | 売却 | 18,418 | $0.00 |
| 2008-07-30 | BAFFI, ROBERT | SVP, Technical Operations | ストックオプション | 売却 | 1,110 | $0.00 |
| 2008-07-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 200 | $30.31 |
| 2008-07-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 150 | $30.15 |
| 2008-07-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 833 | $17.54 |
| 2008-07-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 312 | $14.00 |
| 2008-07-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 521 | $11.74 |
| 2008-07-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 177 | $6.13 |
| 2008-07-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 625 | $0.00 |
| 2008-07-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 833 | $0.00 |
| 2008-07-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 312 | $0.00 |
| 2008-07-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 521 | $0.00 |
| 2008-07-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 177 | $0.00 |
| 2008-07-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 625 | $17.33 |
| 2008-07-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 250 | $30.13 |
| 2008-07-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 250 | $30.48 |
| 2008-07-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 50 | $30.10 |
| 2008-07-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 350 | $30.12 |
| 2008-07-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 500 | $30.21 |
| 2008-07-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 50 | $30.20 |
| 2008-07-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 268 | $30.55 |
| 2008-07-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 250 | $30.32 |
| 2008-07-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 150 | $30.19 |
| 2008-07-15 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 購入 | 5,000 | $6.13 |
| 2008-07-15 | DAVIS, GEORGE ERIC | VP, General Counsel | ストックオプション | 売却 | 5,000 | $0.00 |
| 2008-07-15 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 5,000 | $28.00 |
| 2008-07-08 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 10 | $28.05 |
| 2008-07-08 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 10 | $28.00 |
| 2008-07-08 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 10 | $28.28 |
| 2008-07-08 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 20 | $28.69 |
| 2008-07-08 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 40 | $27.65 |
| 2008-07-08 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 40 | $27.51 |
| 2008-07-08 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 10 | $28.68 |
| 2008-07-08 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 40 | $27.28 |
| 2008-07-08 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 10 | $28.75 |
| 2008-07-08 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 10 | $28.65 |
| 2008-07-08 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 10 | $28.60 |
| 2008-07-08 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 10 | $28.58 |
| 2008-07-08 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 10 | $28.57 |
| 2008-07-08 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 10 | $28.50 |
| 2008-07-08 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 10 | $28.40 |
| 2008-07-08 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 10 | $28.34 |
| 2008-07-08 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 10 | $27.95 |
| 2008-07-08 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 10 | $27.90 |
| 2008-07-08 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 20 | $27.75 |
| 2008-07-08 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 10 | $27.85 |
| 2008-07-08 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 30 | $28.22 |
| 2008-07-08 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 10 | $28.15 |
| 2008-07-07 | MEIER, RICHARD A | Director | 譲渡制限付株式ユニット | 売却 | 1,250 | $0.00 |
| 2008-07-07 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 購入 | 2,000 | $ |
| 2008-07-07 | SWIEDLER, STUART J | SVP, Clinical Affairs | 譲渡制限付株式ユニット | 売却 | 2,000 | $0.00 |
| 2008-07-07 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 購入 | 2,500 | $ |
| 2008-07-07 | ASELAGE, STEVE | SVP, Global Commercial Dev | 譲渡制限付株式ユニット | 売却 | 2,500 | $0.00 |
| 2008-07-07 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 1,000 | $28.03 |
| 2008-07-07 | HERON, ELAINE J | Director | 譲渡制限付株式ユニット | 売却 | 2,500 | $0.00 |
| 2008-07-07 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 3,800 | $28.06 |
| 2008-07-07 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 100 | $28.17 |
| 2008-07-07 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 100 | $28.20 |
| 2008-07-07 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 100 | $28.21 |
| 2008-07-07 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 300 | $28.22 |
| 2008-07-07 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 3,500 | $28.26 |
| 2008-07-07 | GREY, MICHAEL G | Director | 普通株式 | 購入 | 1,250 | $ |
| 2008-07-07 | GREY, MICHAEL G | Director | 譲渡制限付株式ユニット | 売却 | 1,250 | $0.00 |
| 2008-07-07 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 購入 | 2,500 | $ |
| 2008-07-07 | KAKKIS, EMIL D | Chief Medical Officer | 譲渡制限付株式ユニット | 売却 | 2,500 | $0.00 |
| 2008-07-07 | HERON, ELAINE J | Director | 普通株式 | 購入 | 2,500 | $ |
| 2008-07-07 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 1,700 | $28.01 |
| 2008-07-07 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 600 | $28.02 |
| 2008-07-07 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 900 | $27.90 |
| 2008-07-07 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 800 | $27.91 |
| 2008-07-07 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 200 | $27.93 |
| 2008-07-07 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 400 | $27.94 |
| 2008-07-07 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 100 | $27.95 |
| 2008-07-07 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 600 | $27.96 |
| 2008-07-07 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 800 | $27.98 |
| 2008-07-07 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 3,000 | $28.00 |
| 2008-07-07 | LAPALME, PIERRE | Director | 譲渡制限付株式ユニット | 売却 | 3,750 | $0.00 |
| 2008-07-07 | KLEIN, JOSEPH III | Director | 普通株式 | 購入 | 2,500 | $ |
| 2008-07-07 | KLEIN, JOSEPH III | Director | 譲渡制限付株式ユニット | 売却 | 2,500 | $0.00 |
| 2008-07-07 | LAPALME, PIERRE | Director | 普通株式 | 購入 | 3,750 | $ |
| 2008-07-07 | LEWIS, ALAN | Director | 普通株式 | 購入 | 2,500 | $ |
| 2008-07-07 | LEWIS, ALAN | Director | 譲渡制限付株式ユニット | 売却 | 2,500 | $0.00 |
| 2008-07-07 | MEIER, RICHARD A | Director | 普通株式 | 購入 | 1,250 | $ |
| 2008-07-07 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 1,000 | $ |
| 2008-07-07 | WOOD, MARK | VP, Human Resources | 譲渡制限付株式ユニット | 売却 | 1,000 | $0.00 |
| 2008-07-07 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 購入 | 1,500 | $ |
| 2008-07-07 | DAVIS, GEORGE ERIC | VP, General Counsel | 譲渡制限付株式ユニット | 売却 | 1,500 | $0.00 |
| 2008-07-07 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 2,000 | $ |
| 2008-07-07 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 譲渡制限付株式ユニット | 売却 | 2,000 | $0.00 |
| 2008-07-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $ |
| 2008-07-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 譲渡制限付株式ユニット | 売却 | 5,000 | $0.00 |
| 2008-07-07 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 購入 | 2,000 | $ |
| 2008-07-07 | BAFFI, ROBERT | SVP, Technical Operations | 譲渡制限付株式ユニット | 売却 | 2,000 | $0.00 |
| 2008-07-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,500 | $28.43 |
| 2008-07-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,500 | $28.24 |
| 2008-07-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,500 | $28.30 |
| 2008-07-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,500 | $28.34 |
| 2008-07-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | ストックオプション | 売却 | 15,000 | $0.00 |
| 2008-07-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,500 | $28.47 |
| 2008-07-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,500 | $28.46 |
| 2008-07-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,500 | $28.44 |
| 2008-07-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,500 | $28.06 |
| 2008-07-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 購入 | 15,000 | $6.13 |
| 2008-07-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 900 | $28.35 |
| 2008-07-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 600 | $28.36 |
| 2008-07-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,500 | $28.35 |
| 2008-06-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $30.02 |
| 2008-06-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $30.01 |
| 2008-06-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 購入 | 3,528 | $22.00 |
| 2008-06-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 528 | $30.03 |
| 2008-06-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 2,500 | $30.00 |
| 2008-06-30 | BAFFI, ROBERT | SVP, Technical Operations | ストックオプション | 売却 | 3,528 | $0.00 |
| 2008-06-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $30.06 |
| 2008-06-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 833 | $17.54 |
| 2008-06-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 313 | $14.00 |
| 2008-06-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 521 | $11.74 |
| 2008-06-23 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 833 | $0.00 |
| 2008-06-23 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 625 | $0.00 |
| 2008-06-23 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 313 | $0.00 |
| 2008-06-23 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 521 | $0.00 |
| 2008-06-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 230 | $32.96 |
| 2008-06-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 229 | $33.15 |
| 2008-06-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 229 | $32.89 |
| 2008-06-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 229 | $32.76 |
| 2008-06-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 229 | $32.70 |
| 2008-06-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 229 | $32.66 |
| 2008-06-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 225 | $32.21 |
| 2008-06-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 224 | $31.57 |
| 2008-06-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 625 | $17.33 |
| 2008-06-23 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 468 | $32.57 |
| 2008-06-16 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 購入 | 10,000 | $7.84 |
| 2008-06-16 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 2,313 | $33.89 |
| 2008-06-16 | DAVIS, GEORGE ERIC | VP, General Counsel | ストックオプション | 売却 | 10,000 | $0.00 |
| 2008-06-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 3,000 | $6.46 |
| 2008-06-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,000 | $39.00 |
| 2008-06-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 3,000 | $0.00 |
| 2008-06-04 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 140 | $37.67 |
| 2008-06-04 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 177 | $0.00 |
| 2008-06-04 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 321 | $0.00 |
| 2008-06-04 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 834 | $0.00 |
| 2008-06-04 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 130 | $37.44 |
| 2008-06-04 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 133 | $37.30 |
| 2008-06-04 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 130 | $37.40 |
| 2008-06-04 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 177 | $6.13 |
| 2008-06-04 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 312 | $14.00 |
| 2008-06-04 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 834 | $17.54 |
| 2008-06-04 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 130 | $37.83 |
| 2008-06-04 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 130 | $38.02 |
| 2008-06-04 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 130 | $37.70 |
| 2008-06-04 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 130 | $37.68 |
| 2008-06-04 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 130 | $37.79 |
| 2008-06-04 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 140 | $37.78 |
| 2008-06-02 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 600 | $37.59 |
| 2008-06-02 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 458 | $37.57 |
| 2008-06-02 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 購入 | 16,000 | $4.00 |
| 2008-06-02 | KAKKIS, EMIL D | Chief Medical Officer | ストックオプション | 売却 | 16,000 | $0.00 |
| 2008-06-02 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 1,300 | $37.71 |
| 2008-06-02 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 1,000 | $37.67 |
| 2008-06-02 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 1,648 | $37.66 |
| 2008-06-02 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 3,252 | $37.65 |
| 2008-06-02 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 1,200 | $37.64 |
| 2008-06-02 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 1,400 | $37.63 |
| 2008-06-02 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 1,200 | $37.62 |
| 2008-06-02 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 1,300 | $37.61 |
| 2008-06-02 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 3,911 | $37.60 |
| 2008-06-02 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 731 | $37.58 |
| 2008-05-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $38.39 |
| 2008-05-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 598 | $38.38 |
| 2008-05-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $38.37 |
| 2008-05-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $38.36 |
| 2008-05-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 500 | $38.35 |
| 2008-05-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 500 | $38.34 |
| 2008-05-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 2 | $38.32 |
| 2008-05-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $38.31 |
| 2008-05-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $38.30 |
| 2008-05-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $38.29 |
| 2008-05-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 購入 | 11,528 | $22.00 |
| 2008-05-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,100 | $38.42 |
| 2008-05-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 400 | $38.60 |
| 2008-05-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $38.56 |
| 2008-05-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $38.59 |
| 2008-05-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 400 | $38.45 |
| 2008-05-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 600 | $38.44 |
| 2008-05-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $38.43 |
| 2008-05-30 | BAFFI, ROBERT | SVP, Technical Operatons | 普通株式 | 売却 | 400 | $38.77 |
| 2008-05-30 | BAFFI, ROBERT | SVP, Technical Operatons | 普通株式 | 売却 | 100 | $38.76 |
| 2008-05-30 | BAFFI, ROBERT | SVP, Technical Operatons | 普通株式 | 売却 | 200 | $38.70 |
| 2008-05-30 | BAFFI, ROBERT | SVP, Technical Operatons | 普通株式 | 売却 | 200 | $38.68 |
| 2008-05-30 | BAFFI, ROBERT | SVP, Technical Operatons | 普通株式 | 売却 | 100 | $38.64 |
| 2008-05-30 | BAFFI, ROBERT | SVP, Technical Operatons | 普通株式 | 売却 | 100 | $38.62 |
| 2008-05-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $38.41 |
| 2008-05-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 228 | $38.54 |
| 2008-05-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 500 | $38.53 |
| 2008-05-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $38.52 |
| 2008-05-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $38.51 |
| 2008-05-30 | BAFFI, ROBERT | SVP, Technical Operations | ストックオプション | 売却 | 11,528 | $0.00 |
| 2008-05-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $38.50 |
| 2008-05-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,300 | $38.49 |
| 2008-05-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 600 | $38.48 |
| 2008-05-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $38.48 |
| 2008-05-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,000 | $38.47 |
| 2008-05-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $38.46 |
| 2008-05-22 | MEIER, RICHARD A | Director | 譲渡制限付株式ユニット | 購入 | 2,500 | $0.00 |
| 2008-05-22 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 購入 | 425,000 | $0.00 |
| 2008-05-22 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 譲渡制限付株式ユニット | 購入 | 30,000 | $0.00 |
| 2008-05-22 | BAFFI, ROBERT | SVP, Technical Operations | ストックオプション | 購入 | 65,000 | $0.00 |
| 2008-05-22 | BAFFI, ROBERT | SVP, Technical Operations | 譲渡制限付株式ユニット | 購入 | 8,000 | $0.00 |
| 2008-05-22 | LAPALME, PIERRE | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2008-05-22 | LAPALME, PIERRE | Director | 譲渡制限付株式ユニット | 購入 | 2,500 | $0.00 |
| 2008-05-22 | ASELAGE, STEVE | SVP, Global Commercial Dev. | ストックオプション | 購入 | 80,000 | $0.00 |
| 2008-05-22 | ASELAGE, STEVE | SVP, Global Commercial Dev. | 譲渡制限付株式ユニット | 購入 | 10,000 | $0.00 |
| 2008-05-22 | KLEIN, JOSEPH III | Director | 普通株式 | 購入 | 15,000 | $0.00 |
| 2008-05-22 | KLEIN, JOSEPH III | Director | 譲渡制限付株式ユニット | 購入 | 2,500 | $0.00 |
| 2008-05-22 | HERON, ELAINE J | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2008-05-22 | HERON, ELAINE J | Director | 譲渡制限付株式ユニット | 購入 | 2,500 | $0.00 |
| 2008-05-22 | GREY, MICHAEL G | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2008-05-22 | GREY, MICHAEL G | Director | 譲渡制限付株式ユニット | 購入 | 2,500 | $0.00 |
| 2008-05-22 | COOPER, JEFFREY H | SVP, Chief Financial Officer | ストックオプション | 購入 | 60,000 | $0.00 |
| 2008-05-22 | KAKKIS, EMIL D | Chief Medical Officer | 譲渡制限付株式ユニット | 購入 | 9,000 | $0.00 |
| 2008-05-22 | KAKKIS, EMIL D | Chief Medical Officer | ストックオプション | 購入 | 70,000 | $0.00 |
| 2008-05-22 | SWIEDLER, STUART J | SVP, Clinical Affairs | 譲渡制限付株式ユニット | 購入 | 7,000 | $0.00 |
| 2008-05-22 | LAWLIS, V BRYAN | Director | 譲渡制限付株式ユニット | 購入 | 2,500 | $0.00 |
| 2008-05-22 | LAWLIS, V BRYAN | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2008-05-22 | DAVIS, GEORGE ERIC | VP, General Counsel | 譲渡制限付株式ユニット | 購入 | 7,000 | $0.00 |
| 2008-05-22 | DAVIS, GEORGE ERIC | VP, General Counsel | ストックオプション | 購入 | 50,000 | $0.00 |
| 2008-05-22 | LEWIS, ALAN | Director | 譲渡制限付株式ユニット | 購入 | 2,500 | $0.00 |
| 2008-05-22 | LEWIS, ALAN | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2008-05-22 | WOOD, MARK | VP, Human Resources | ストックオプション | 購入 | 40,000 | $0.00 |
| 2008-05-22 | WOOD, MARK | VP, Human Resources | 譲渡制限付株式ユニット | 購入 | 5,000 | $0.00 |
| 2008-05-22 | SWIEDLER, STUART J | SVP, Clinical Affairs | ストックオプション | 購入 | 55,000 | $0.00 |
| 2008-05-22 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 譲渡制限付株式ユニット | 購入 | 8,000 | $0.00 |
| 2008-05-22 | MEIER, RICHARD A | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2008-05-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 521 | $6.37 |
| 2008-05-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 200 | $38.92 |
| 2008-05-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 200 | $38.90 |
| 2008-05-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 200 | $38.84 |
| 2008-05-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 200 | $38.86 |
| 2008-05-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 200 | $39.05 |
| 2008-05-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 300 | $38.89 |
| 2008-05-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 150 | $39.63 |
| 2008-05-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 167 | $39.83 |
| 2008-05-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 625 | $17.33 |
| 2008-05-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 521 | $11.74 |
| 2008-05-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 521 | $0.00 |
| 2008-05-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 625 | $0.00 |
| 2008-05-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 50 | $39.62 |
| 2008-05-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 400 | $39.10 |
| 2008-05-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,600 | $39.11 |
| 2008-05-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2008-05-15 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $6.46 |
| 2008-05-13 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 購入 | 10,000 | $11.74 |
| 2008-05-13 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 5,188 | $39.10 |
| 2008-05-13 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 100 | $39.18 |
| 2008-05-13 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 300 | $39.17 |
| 2008-05-13 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 200 | $39.16 |
| 2008-05-13 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 4,212 | $39.15 |
| 2008-05-13 | DAVIS, GEORGE ERIC | VP, General Counsel | ストックオプション | 売却 | 10,000 | $0.00 |
| 2008-05-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 200 | $39.18 |
| 2008-05-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2008-05-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $6.46 |
| 2008-05-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 100 | $39.20 |
| 2008-05-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 3,366 | $39.15 |
| 2008-05-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 100 | $39.16 |
| 2008-05-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 100 | $39.21 |
| 2008-05-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,134 | $39.17 |
| 2008-05-09 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 8,000 | $6.46 |
| 2008-05-09 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 8,000 | $0.00 |
| 2008-05-09 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 100 | $39.37 |
| 2008-05-09 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $38.39 |
| 2008-05-09 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,900 | $39.36 |
| 2008-05-06 | ASELAGE, STEVE | SVP, Global Commercial Dev. | 普通株式 | 売却 | 16,200 | $37.75 |
| 2008-05-06 | ASELAGE, STEVE | SVP, Global Commercial Dev. | 普通株式 | 購入 | 205 | $7.16 |
| 2008-05-06 | ASELAGE, STEVE | SVP, Global Commercial Dev. | 普通株式 | 購入 | 12,000 | $11.74 |
| 2008-05-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,605 | $36.53 |
| 2008-05-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 400 | $36.56 |
| 2008-05-05 | ASELAGE, STEVE | SVP, Global Commercial Dev. | ストックオプション | 売却 | 205 | $0.00 |
| 2008-05-05 | ASELAGE, STEVE | SVP, Global Commercial Dev. | ストックオプション | 売却 | 12,000 | $0.00 |
| 2008-05-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $6.46 |
| 2008-05-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 400 | $36.57 |
| 2008-05-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 700 | $36.58 |
| 2008-05-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 200 | $36.54 |
| 2008-05-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 695 | $36.55 |
| 2008-05-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2008-05-02 | ASELAGE, STEVE | SVP, Global Commercial Dev. | 普通株式 | 購入 | 2,900 | $7.16 |
| 2008-05-02 | ASELAGE, STEVE | SVP, Global Commercial Dev. | ストックオプション | 売却 | 2,900 | $0.00 |
| 2008-05-02 | ASELAGE, STEVE | SVP, Global Commercial Dev. | 普通株式 | 売却 | 3,800 | $37.75 |
| 2008-05-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $6.46 |
| 2008-05-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 100 | $36.50 |
| 2008-05-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $37.24 |
| 2008-05-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 10,000 | $0.00 |
| 2008-05-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 900 | $37.65 |
| 2008-05-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 800 | $37.59 |
| 2008-05-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 1,399 | $37.57 |
| 2008-05-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 300 | $37.36 |
| 2008-05-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $6.46 |
| 2008-05-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 406 | $37.56 |
| 2008-05-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,553 | $37.24 |
| 2008-05-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,500 | $36.00 |
| 2008-05-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 500 | $37.60 |
| 2008-05-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 500 | $37.70 |
| 2008-05-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $37.50 |
| 2008-05-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 100 | $37.45 |
| 2008-05-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 300 | $37.00 |
| 2008-05-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 2,000 | $37.55 |
| 2008-05-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 2,900 | $37.54 |
| 2008-05-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 900 | $37.51 |
| 2008-05-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 800 | $37.50 |
| 2008-05-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 1,095 | $37.49 |
| 2008-05-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2008-05-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 599 | $37.48 |
| 2008-05-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 1,200 | $37.47 |
| 2008-05-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 購入 | 18,000 | $4.00 |
| 2008-05-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 1,501 | $37.31 |
| 2008-05-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 100 | $37.33 |
| 2008-05-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 300 | $37.34 |
| 2008-05-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 200 | $37.41 |
| 2008-05-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 500 | $37.35 |
| 2008-05-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 400 | $37.40 |
| 2008-05-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 100 | $37.42 |
| 2008-05-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 200 | $37.43 |
| 2008-05-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 900 | $37.46 |
| 2008-05-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 500 | $37.39 |
| 2008-05-01 | KAKKIS, EMIL D | Chief Medical Officer | ストックオプション | 売却 | 18,000 | $0.00 |
| 2008-04-30 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 100 | $36.81 |
| 2008-04-30 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 100 | $36.59 |
| 2008-04-30 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 1,070 | $13.95 |
| 2008-04-30 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 200 | $36.57 |
| 2008-04-30 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 100 | $36.50 |
| 2008-04-30 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 300 | $36.48 |
| 2008-04-30 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 100 | $36.46 |
| 2008-04-30 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 100 | $36.43 |
| 2008-04-30 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 200 | $36.41 |
| 2008-04-30 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 200 | $36.40 |
| 2008-04-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 購入 | 1,754 | $10.37 |
| 2008-04-30 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 100 | $36.38 |
| 2008-04-30 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 200 | $36.36 |
| 2008-04-30 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 100 | $36.35 |
| 2008-04-30 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 500 | $36.33 |
| 2008-04-30 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 300 | $36.29 |
| 2008-04-30 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 100 | $36.28 |
| 2008-04-30 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 100 | $36.25 |
| 2008-04-30 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 8 | $36.23 |
| 2008-04-30 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 392 | $36.22 |
| 2008-04-30 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 200 | $36.21 |
| 2008-04-30 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 100 | $36.21 |
| 2008-04-30 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 100 | $36.18 |
| 2008-04-30 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 100 | $36.16 |
| 2008-04-30 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 200 | $36.17 |
| 2008-04-30 | DAVIS, GEORGE ERIC | VP, General Counsel | ストックオプション | 売却 | 5,000 | $0.00 |
| 2008-04-30 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 100 | $36.61 |
| 2008-04-30 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 100 | $36.60 |
| 2008-04-30 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 100 | $36.10 |
| 2008-04-30 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 300 | $36.03 |
| 2008-04-30 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 100 | $35.81 |
| 2008-04-30 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 100 | $35.52 |
| 2008-04-30 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 購入 | 5,000 | $7.84 |
| 2008-04-30 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 購入 | 1,810 | $10.37 |
| 2008-04-30 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 100 | $36.74 |
| 2008-04-30 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 100 | $36.70 |
| 2008-04-30 | ASELAGE, STEVE | SVP, Global Commercial Dev. | 普通株式 | 購入 | 1,526 | $10.37 |
| 2008-04-30 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 100 | $36.68 |
| 2008-04-30 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 2,049 | $10.37 |
| 2008-04-30 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 購入 | 1,640 | $10.37 |
| 2008-04-29 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 購入 | 75,000 | $4.00 |
| 2008-04-29 | KAKKIS, EMIL D | Chief Medical Officer | ストックオプション | 売却 | 75,000 | $0.00 |
| 2008-04-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 313 | $14.00 |
| 2008-04-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 833 | $17.54 |
| 2008-04-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 625 | $17.33 |
| 2008-04-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 290 | $33.79 |
| 2008-04-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 600 | $33.95 |
| 2008-04-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 300 | $33.90 |
| 2008-04-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 521 | $6.37 |
| 2008-04-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 177 | $6.13 |
| 2008-04-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 521 | $11.74 |
| 2008-04-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 500 | $34.07 |
| 2008-04-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 300 | $33.92 |
| 2008-04-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 300 | $34.11 |
| 2008-04-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 300 | $34.10 |
| 2008-04-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 400 | $34.06 |
| 2008-04-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 521 | $0.00 |
| 2008-04-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 177 | $0.00 |
| 2008-04-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 313 | $0.00 |
| 2008-04-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 833 | $0.00 |
| 2008-04-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 625 | $0.00 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,300 | $36.99 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,200 | $37.17 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 116 | $37.18 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $37.22 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $37.22 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $37.23 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $37.23 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $37.26 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 購入 | 23,762 | $7.76 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 購入 | 15,000 | $6.13 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 900 | $36.66 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 575 | $36.69 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 125 | $36.70 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $36.71 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,300 | $36.72 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $36.76 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $36.77 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,361 | $36.80 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 500 | $36.80 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,280 | $36.81 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 900 | $36.82 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 539 | $36.83 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 320 | $36.84 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 950 | $36.85 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 900 | $36.86 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 583 | $36.87 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $36.89 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,929 | $36.90 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $36.92 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $36.92 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 303 | $36.94 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,300 | $36.95 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,200 | $36.96 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,200 | $36.97 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,400 | $36.98 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,900 | $37.00 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,400 | $37.01 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | ストックオプション | 売却 | 23,762 | $0.00 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | ストックオプション | 売却 | 15,000 | $0.00 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,400 | $37.02 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,400 | $37.03 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $37.04 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 600 | $37.05 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 497 | $37.06 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $37.07 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $37.08 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,100 | $37.09 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,000 | $37.10 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 600 | $37.11 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 514 | $37.12 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,269 | $37.13 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 901 | $37.14 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,900 | $37.15 |
| 2008-04-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 2,000 | $37.16 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 1,300 | $35.91 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 200 | $36.09 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 200 | $36.12 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 300 | $36.09 |
| 2008-04-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 50 | $35.84 |
| 2008-04-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,500 | $35.84 |
| 2008-04-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,250 | $35.83 |
| 2008-04-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,250 | $35.76 |
| 2008-04-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 購入 | 12,500 | $6.13 |
| 2008-04-01 | ASELAGE, STEVE | SVP, Global Commercial Dev | ストックオプション | 売却 | 805 | $0.00 |
| 2008-04-01 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 165 | $36.47 |
| 2008-04-01 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 149 | $36.24 |
| 2008-04-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | ストックオプション | 売却 | 12,500 | $0.00 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 57 | $36.00 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 269 | $35.87 |
| 2008-04-01 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 購入 | 805 | $7.16 |
| 2008-04-01 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 80 | $35.83 |
| 2008-04-01 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 80 | $35.78 |
| 2008-04-01 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 80 | $35.75 |
| 2008-04-01 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 80 | $35.83 |
| 2008-04-01 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 80 | $35.88 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 200 | $35.99 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 200 | $35.93 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 500 | $35.92 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 400 | $36.13 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 200 | $36.11 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 100 | $35.97 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 200 | $35.69 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 100 | $35.90 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 700 | $35.81 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 1,162 | $35.86 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 100 | $35.87 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 800 | $35.85 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 400 | $35.82 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 700 | $35.71 |
| 2008-04-01 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 91 | $36.05 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 購入 | 18,000 | $4.00 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 200 | $35.73 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 300 | $35.68 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 200 | $35.70 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 200 | $35.66 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 300 | $35.65 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 200 | $35.68 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 200 | $35.67 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 200 | $35.70 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 100 | $35.80 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 670 | $35.78 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 30 | $35.74 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 200 | $35.76 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 250 | $35.84 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 550 | $35.83 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 200 | $36.09 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 537 | $36.08 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 106 | $36.01 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | ストックオプション | 売却 | 18,000 | $0.00 |
| 2008-04-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,000 | $35.84 |
| 2008-04-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 2,000 | $36.24 |
| 2008-04-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,000 | $36.06 |
| 2008-04-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,200 | $35.85 |
| 2008-04-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 315 | $35.87 |
| 2008-04-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 935 | $35.88 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 800 | $35.71 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 200 | $35.71 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 200 | $35.70 |
| 2008-04-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 2,000 | $36.46 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 100 | $35.69 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 200 | $35.70 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 100 | $35.69 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 200 | $35.68 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 200 | $35.65 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 700 | $35.66 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 100 | $35.72 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 700 | $35.68 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 100 | $35.82 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 200 | $35.86 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 200 | $35.87 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 569 | $35.88 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 100 | $35.88 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 100 | $35.92 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 200 | $35.89 |
| 2008-04-01 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 500 | $35.90 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $35.80 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 870 | $36.22 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $36.23 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 600 | $35.46 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $35.46 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 500 | $35.47 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $35.47 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $35.48 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $35.48 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $35.49 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,000 | $35.50 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,000 | $35.51 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $35.52 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $35.54 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 400 | $35.55 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $35.60 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $35.61 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,400 | $36.04 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 190 | $36.05 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,100 | $36.06 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 219 | $36.07 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 403 | $36.08 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $36.09 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 497 | $36.10 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $36.14 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 600 | $36.15 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 700 | $36.16 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 800 | $36.17 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $36.19 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,300 | $36.20 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $36.21 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 230 | $36.25 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $36.33 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $36.36 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $36.39 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $36.40 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $36.41 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 400 | $36.42 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 600 | $36.43 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 500 | $36.45 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $35.70 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $35.71 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,700 | $35.74 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,200 | $35.75 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $35.76 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 400 | $35.77 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $35.78 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 600 | $35.79 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $35.80 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 600 | $35.81 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 500 | $35.83 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $35.84 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $35.85 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $35.86 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $35.87 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 800 | $35.88 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,798 | $35.90 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $35.91 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $35.93 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $35.94 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $35.95 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $35.96 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $35.98 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 400 | $35.99 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,000 | $36.00 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $36.00 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,491 | $36.01 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 400 | $36.02 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $36.03 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 購入 | 8,760 | $12.10 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 購入 | 26,238 | $7.76 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $35.32 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 400 | $35.35 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 600 | $35.36 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $35.38 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $35.44 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $35.45 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | ストックオプション | 売却 | 26,238 | $0.00 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $35.62 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 500 | $35.63 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $35.64 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 400 | $35.65 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $35.66 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $35.67 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $35.68 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 700 | $35.69 |
| 2008-03-25 | BAFFI, ROBERT | SVP, Technical Operations | ストックオプション | 売却 | 8,760 | $0.00 |
| 2008-03-24 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 833 | $0.00 |
| 2008-03-24 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 625 | $0.00 |
| 2008-03-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 177 | $6.13 |
| 2008-03-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 521 | $11.74 |
| 2008-03-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 625 | $17.33 |
| 2008-03-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 300 | $34.00 |
| 2008-03-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 300 | $35.16 |
| 2008-03-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 300 | $35.31 |
| 2008-03-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 312 | $14.00 |
| 2008-03-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 833 | $17.54 |
| 2008-03-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 250 | $35.20 |
| 2008-03-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 300 | $35.05 |
| 2008-03-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 300 | $35.24 |
| 2008-03-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 300 | $34.75 |
| 2008-03-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 339 | $35.22 |
| 2008-03-24 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 521 | $0.00 |
| 2008-03-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 300 | $35.12 |
| 2008-03-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 300 | $35.43 |
| 2008-03-24 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 177 | $0.00 |
| 2008-03-24 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 312 | $0.00 |
| 2008-03-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 521 | $6.37 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 2,400 | $32.25 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 700 | $32.28 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $32.29 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 500 | $32.30 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | ストックオプション | 売却 | 41,240 | $0.00 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | ストックオプション | 売却 | 5,000 | $0.00 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,300 | $32.47 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,800 | $32.48 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $32.49 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,305 | $32.50 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 395 | $32.51 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,800 | $32.52 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,000 | $32.53 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $32.54 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 900 | $32.55 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 336 | $32.56 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 900 | $32.57 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 700 | $32.58 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 900 | $32.59 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 600 | $32.60 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $32.84 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $32.85 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,100 | $32.86 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $32.89 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $32.92 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $32.31 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 900 | $32.32 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 800 | $32.33 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $32.34 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,400 | $32.35 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $32.36 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 400 | $32.37 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $32.38 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $32.39 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 3,400 | $32.40 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 2,300 | $32.41 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $32.42 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 600 | $32.43 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 600 | $32.44 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 2,000 | $32.45 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 600 | $32.46 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $32.61 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $32.62 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $32.63 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $32.65 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,400 | $32.66 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $32.67 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 112 | $32.76 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $32.76 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,500 | $32.75 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $32.75 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $32.74 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 700 | $32.73 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $32.72 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $32.71 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 364 | $32.70 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $32.69 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $32.82 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $32.77 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $32.78 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 購入 | 46,240 | $12.10 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $31.76 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $31.85 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 700 | $31.86 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $31.92 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 700 | $31.88 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $31.95 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $31.96 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 555 | $31.98 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 11 | $31.99 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 89 | $32.00 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $32.01 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 245 | $32.08 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $32.09 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $32.09 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,240 | $32.10 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 700 | $32.12 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $32.14 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 88 | $32.15 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $32.18 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $32.19 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $32.20 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 600 | $32.21 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $32.22 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 600 | $32.23 |
| 2008-03-18 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 800 | $32.24 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $34.31 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $34.15 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $33.13 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 400 | $33.14 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 400 | $33.15 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 500 | $33.17 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $33.19 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $33.20 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $33.20 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 400 | $33.21 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $32.55 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $32.57 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $32.59 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $32.79 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $32.81 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $33.14 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $33.16 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $33.16 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $33.18 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $33.19 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 2,100 | $33.20 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 21 | $33.22 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $33.23 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,079 | $33.24 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $33.25 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 421 | $33.26 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 79 | $33.27 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 購入 | 38,243 | $9.50 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $32.60 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $32.61 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $32.62 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 800 | $32.64 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $32.68 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $32.70 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 600 | $32.71 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 400 | $32.72 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $32.83 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $32.85 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $32.87 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $32.91 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $32.92 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $32.93 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $32.96 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | ストックオプション | 売却 | 33,333 | $0.00 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $33.40 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $33.46 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,100 | $34.19 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $34.28 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $34.30 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $34.32 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $34.33 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $34.35 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 2,043 | $34.44 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,000 | $34.50 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $33.28 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $33.29 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $33.30 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,457 | $33.31 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $33.33 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 400 | $33.34 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $33.35 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 700 | $33.36 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $33.48 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $33.49 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 900 | $33.50 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 900 | $33.51 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $33.60 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $33.71 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $33.76 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $33.78 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $33.85 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $34.10 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,000 | $34.11 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $33.03 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 400 | $33.04 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 668 | $33.05 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 475 | $33.06 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $33.07 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,250 | $33.09 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 600 | $33.12 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 600 | $33.54 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $33.61 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 98 | $33.62 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 102 | $33.63 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $33.64 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 500 | $33.65 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 500 | $33.66 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 2,200 | $33.70 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $33.86 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 700 | $33.08 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 650 | $33.10 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $33.11 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $32.88 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $32.89 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $32.93 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $32.94 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 700 | $32.95 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $32.97 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 800 | $32.99 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $33.01 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $33.02 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | ストックオプション | 売却 | 4,910 | $0.00 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $34.38 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $34.36 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $34.32 |
| 2008-03-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,000 | $34.14 |
| 2008-03-06 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 400 | $38.14 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 300 | $37.64 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 700 | $37.65 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 600 | $37.66 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 200 | $37.67 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 793 | $37.68 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 600 | $37.69 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 900 | $37.70 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 100 | $37.71 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 100 | $37.72 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 900 | $37.73 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 700 | $37.74 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 800 | $37.75 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 100 | $37.76 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 100 | $37.77 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 200 | $37.78 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 200 | $37.80 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 100 | $37.82 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 100 | $37.83 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 1,000 | $37.85 |
| 2008-03-06 | HERON, ELAINE J | Director | ストックオプション | 売却 | 30,000 | $0.00 |
| 2008-03-06 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 購入 | 18,000 | $4.00 |
| 2008-03-06 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 100 | $37.99 |
| 2008-03-06 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 300 | $38.00 |
| 2008-03-06 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 1,300 | $38.01 |
| 2008-03-06 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 1,200 | $38.02 |
| 2008-03-06 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 500 | $38.03 |
| 2008-03-06 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 1,200 | $38.04 |
| 2008-03-06 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 500 | $38.05 |
| 2008-03-06 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 500 | $38.06 |
| 2008-03-06 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 400 | $38.07 |
| 2008-03-06 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 200 | $38.08 |
| 2008-03-06 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 300 | $38.10 |
| 2008-03-06 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 400 | $38.11 |
| 2008-03-06 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 200 | $38.12 |
| 2008-03-06 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 800 | $38.13 |
| 2008-03-06 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 500 | $38.23 |
| 2008-03-06 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 2,300 | $38.26 |
| 2008-03-06 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 1,500 | $38.27 |
| 2008-03-06 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 200 | $38.29 |
| 2008-03-06 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 200 | $38.31 |
| 2008-03-06 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 100 | $38.34 |
| 2008-03-06 | KAKKIS, EMIL D | Chief Medical Officer | ストックオプション | 売却 | 18,000 | $0.00 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 138 | $38.31 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 100 | $37.86 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 100 | $37.90 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 547 | $38.06 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 1,000 | $38.07 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 800 | $38.09 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 900 | $38.14 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 600 | $38.15 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 100 | $38.19 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 400 | $38.20 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 200 | $38.21 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 300 | $38.22 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 200 | $38.25 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 200 | $38.26 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 2,100 | $38.10 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 1,004 | $38.16 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 300 | $38.17 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 1,000 | $38.24 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 400 | $38.27 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 購入 | 30,000 | $10.38 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 購入 | 30,000 | $5.12 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 100 | $37.47 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 67 | $37.49 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 200 | $37.50 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 100 | $37.51 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 33 | $37.55 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 218 | $37.59 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 100 | $37.61 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 500 | $37.62 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 100 | $37.63 |
| 2008-03-06 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 300 | $38.15 |
| 2008-03-06 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 200 | $38.16 |
| 2008-03-06 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 200 | $38.20 |
| 2008-03-06 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 300 | $38.21 |
| 2008-03-06 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 200 | $38.22 |
| 2008-03-06 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 700 | $38.24 |
| 2008-03-06 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 3,000 | $38.25 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 300 | $38.28 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 400 | $38.29 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 200 | $38.30 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 600 | $38.32 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 300 | $38.33 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 500 | $38.34 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 300 | $38.39 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 700 | $38.41 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 100 | $38.42 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 100 | $37.95 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 100 | $37.96 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 200 | $38.00 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 300 | $38.01 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 500 | $38.02 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 700 | $38.03 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 700 | $38.04 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 700 | $38.05 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 1,200 | $38.08 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 600 | $38.11 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 800 | $38.12 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 300 | $38.13 |
| 2008-03-06 | HERON, ELAINE J | Director | 普通株式 | 売却 | 100 | $38.38 |
| 2008-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 300 | $38.19 |
| 2008-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 500 | $38.04 |
| 2008-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 800 | $38.03 |
| 2008-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 600 | $38.42 |
| 2008-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 204 | $38.13 |
| 2008-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 600 | $38.24 |
| 2008-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 1,100 | $38.23 |
| 2008-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 600 | $38.22 |
| 2008-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 1,000 | $38.31 |
| 2008-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 700 | $38.33 |
| 2008-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 500 | $38.34 |
| 2008-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 500 | $38.35 |
| 2008-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 100 | $38.36 |
| 2008-03-05 | GREY, MICHAEL G | Director | ストックオプション | 売却 | 30,000 | $0.00 |
| 2008-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 1,700 | $38.16 |
| 2008-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 500 | $38.27 |
| 2008-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 300 | $38.30 |
| 2008-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 100 | $38.15 |
| 2008-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 1,100 | $38.14 |
| 2008-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 1,200 | $38.10 |
| 2008-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 100 | $38.39 |
| 2008-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 900 | $38.40 |
| 2008-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 1,400 | $38.41 |
| 2008-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 100 | $38.43 |
| 2008-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 200 | $38.44 |
| 2008-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 200 | $38.45 |
| 2008-03-05 | GREY, MICHAEL G | Director | 普通株式 | 購入 | 30,000 | $10.33 |
| 2008-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 1,000 | $38.06 |
| 2008-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 1,600 | $38.07 |
| 2008-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 100 | $38.08 |
| 2008-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 1,900 | $38.11 |
| 2008-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 900 | $38.21 |
| 2008-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 443 | $38.18 |
| 2008-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 950 | $38.17 |
| 2008-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 900 | $38.20 |
| 2008-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 800 | $38.05 |
| 2008-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 200 | $38.26 |
| 2008-03-05 | GREY, MICHAEL G | Director | 普通株式 | 売却 | 903 | $38.25 |
| 2008-03-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 4,000 | $6.46 |
| 2008-03-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 4,000 | $0.00 |
| 2008-03-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 4,000 | $38.00 |
| 2008-03-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 500 | $38.10 |
| 2008-03-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 700 | $38.11 |
| 2008-03-03 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 購入 | 28,000 | $11.74 |
| 2008-03-03 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 40,000 | $38.00 |
| 2008-03-03 | ASELAGE, STEVE | SVP, Global Commercial Dev | ストックオプション | 売却 | 28,000 | $0.00 |
| 2008-03-03 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 購入 | 37,000 | $7.16 |
| 2008-03-03 | ASELAGE, STEVE | SVP, Global Commercial Dev | ストックオプション | 売却 | 37,000 | $0.00 |
| 2008-03-03 | DAVIS, GEORGE ERIC | VP, General Counsel | ストックオプション | 売却 | 4,000 | $0.00 |
| 2008-03-03 | KLEIN, JOSEPH III | Director | 普通株式 | 売却 | 10,000 | $37.80 |
| 2008-03-03 | KLEIN, JOSEPH III | Director | 普通株式 | 売却 | 1,300 | $38.10 |
| 2008-03-03 | KLEIN, JOSEPH III | Director | 普通株式 | 売却 | 200 | $38.09 |
| 2008-03-03 | KLEIN, JOSEPH III | Director | 普通株式 | 売却 | 1,004 | $38.08 |
| 2008-03-03 | KLEIN, JOSEPH III | Director | 普通株式 | 売却 | 914 | $38.07 |
| 2008-03-03 | KLEIN, JOSEPH III | Director | 普通株式 | 売却 | 100 | $38.06 |
| 2008-03-03 | KLEIN, JOSEPH III | Director | 普通株式 | 売却 | 1,000 | $38.03 |
| 2008-03-03 | KLEIN, JOSEPH III | Director | 普通株式 | 売却 | 500 | $38.01 |
| 2008-03-03 | KLEIN, JOSEPH III | Director | 普通株式 | 売却 | 4,982 | $38.00 |
| 2008-03-03 | HERON, ELAINE J | Director | 普通株式 | 売却 | 20,000 | $38.47 |
| 2008-03-03 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 購入 | 16,000 | $7.84 |
| 2008-03-03 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 購入 | 4,000 | $6.13 |
| 2008-03-03 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 20,000 | $38.00 |
| 2008-03-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 2,000 | $6.46 |
| 2008-03-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 200 | $38.12 |
| 2008-03-03 | DAVIS, GEORGE ERIC | VP, General Counsel | ストックオプション | 売却 | 16,000 | $0.00 |
| 2008-03-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 100 | $38.17 |
| 2008-03-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 300 | $38.13 |
| 2008-03-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 200 | $38.16 |
| 2008-03-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 2,000 | $0.00 |
| 2008-02-29 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 25 | $37.65 |
| 2008-02-29 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 18,000 | $6.46 |
| 2008-02-29 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 8,942 | $38.00 |
| 2008-02-29 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,600 | $38.01 |
| 2008-02-29 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 200 | $38.02 |
| 2008-02-29 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,953 | $37.92 |
| 2008-02-29 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 25 | $38.06 |
| 2008-02-29 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 58 | $37.59 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 31,250 | $11.74 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 1,100 | $37.53 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 400 | $37.55 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 33 | $37.64 |
| 2008-02-29 | KLEIN, JOSEPH III | Director | 普通株式 | 購入 | 30,000 | $14.21 |
| 2008-02-29 | KLEIN, JOSEPH III | Director | ストックオプション | 売却 | 30,000 | $0.00 |
| 2008-02-29 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,189 | $37.91 |
| 2008-02-29 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 18,000 | $0.00 |
| 2008-02-29 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 183 | $38.03 |
| 2008-02-29 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 825 | $38.06 |
| 2008-02-29 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 200 | $38.08 |
| 2008-02-29 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 450 | $38.16 |
| 2008-02-29 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 200 | $38.18 |
| 2008-02-29 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 200 | $38.25 |
| 2008-02-29 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 200 | $38.33 |
| 2008-02-29 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 5,000 | $38.47 |
| 2008-02-29 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 250 | $38.16 |
| 2008-02-29 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 200 | $38.18 |
| 2008-02-29 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 200 | $38.24 |
| 2008-02-29 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 200 | $38.28 |
| 2008-02-29 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 100 | $38.33 |
| 2008-02-29 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 5,000 | $38.47 |
| 2008-02-29 | LAPALME, PIERRE | Director | 普通株式 | 購入 | 15,000 | $5.92 |
| 2008-02-29 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 400 | $37.53 |
| 2008-02-29 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 100 | $37.56 |
| 2008-02-29 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 1,000 | $37.57 |
| 2008-02-29 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 200 | $37.60 |
| 2008-02-29 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 342 | $37.61 |
| 2008-02-29 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 175 | $37.62 |
| 2008-02-29 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 200 | $37.68 |
| 2008-02-29 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 100 | $37.69 |
| 2008-02-29 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 400 | $37.70 |
| 2008-02-29 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 300 | $37.71 |
| 2008-02-29 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 700 | $37.75 |
| 2008-02-29 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 600 | $37.76 |
| 2008-02-29 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 100 | $37.79 |
| 2008-02-29 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 100 | $37.82 |
| 2008-02-29 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 200 | $37.83 |
| 2008-02-29 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 200 | $37.85 |
| 2008-02-29 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 400 | $37.88 |
| 2008-02-29 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 200 | $37.89 |
| 2008-02-29 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 525 | $37.92 |
| 2008-02-29 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 200 | $37.94 |
| 2008-02-29 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 100 | $37.95 |
| 2008-02-29 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 200 | $37.96 |
| 2008-02-29 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 700 | $37.97 |
| 2008-02-29 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 100 | $37.98 |
| 2008-02-29 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 400 | $37.99 |
| 2008-02-29 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 658 | $38.01 |
| 2008-02-29 | LAPALME, PIERRE | Director | 普通株式 | 売却 | 342 | $38.02 |
| 2008-02-29 | LAPALME, PIERRE | Director | ストックオプション | 売却 | 15,000 | $0.00 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 300 | $37.82 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 500 | $37.89 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 1,800 | $37.92 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 1,100 | $37.96 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 800 | $37.97 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 300 | $37.98 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 600 | $37.99 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 405 | $38.00 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 100 | $38.01 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 2,084 | $8.10 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 1,042 | $7.76 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 1,250 | $5.15 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 19,999 | $6.13 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 7,400 | $37.56 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 8,900 | $37.57 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 3,350 | $37.58 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 525 | $37.59 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 10,800 | $37.60 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 1,666 | $37.61 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 1,208 | $37.62 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 200 | $37.63 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 2,381 | $37.65 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 700 | $37.66 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 900 | $37.67 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 1,900 | $37.68 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 1,017 | $37.69 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 883 | $37.70 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 557 | $37.72 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 100 | $37.73 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 100 | $37.74 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 1,400 | $37.75 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 1,100 | $37.76 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 2,300 | $37.77 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 500 | $37.78 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 300 | $37.79 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | ストックオプション | 売却 | 2,084 | $0.00 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | ストックオプション | 売却 | 1,042 | $0.00 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | ストックオプション | 売却 | 1,250 | $0.00 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | ストックオプション | 売却 | 19,999 | $0.00 |
| 2008-02-29 | COOPER, JEFFREY H | SVP, Chief Financial Officer | ストックオプション | 売却 | 31,250 | $0.00 |
| 2008-02-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 625 | $17.33 |
| 2008-02-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 300 | $35.93 |
| 2008-02-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 100 | $36.03 |
| 2008-02-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 190 | $36.04 |
| 2008-02-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 521 | $0.00 |
| 2008-02-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 300 | $37.73 |
| 2008-02-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 625 | $0.00 |
| 2008-02-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 834 | $0.00 |
| 2008-02-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 313 | $0.00 |
| 2008-02-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 520 | $0.00 |
| 2008-02-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 177 | $0.00 |
| 2008-02-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 300 | $37.24 |
| 2008-02-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 300 | $36.41 |
| 2008-02-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 300 | $36.32 |
| 2008-02-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 600 | $36.24 |
| 2008-02-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 300 | $36.23 |
| 2008-02-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 300 | $36.19 |
| 2008-02-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 521 | $6.37 |
| 2008-02-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 177 | $6.13 |
| 2008-02-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 520 | $11.74 |
| 2008-02-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 313 | $14.00 |
| 2008-02-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 834 | $17.54 |
| 2008-01-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 299 | $36.24 |
| 2008-01-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 299 | $35.00 |
| 2008-01-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 100 | $36.44 |
| 2008-01-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 299 | $36.39 |
| 2008-01-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 521 | $11.74 |
| 2008-01-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 312 | $14.00 |
| 2008-01-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 178 | $6.13 |
| 2008-01-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 299 | $36.37 |
| 2008-01-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 299 | $36.34 |
| 2008-01-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 521 | $6.37 |
| 2008-01-22 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 625 | $0.00 |
| 2008-01-22 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 833 | $0.00 |
| 2008-01-22 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 312 | $0.00 |
| 2008-01-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 234 | $36.70 |
| 2008-01-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 199 | $36.43 |
| 2008-01-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 625 | $17.33 |
| 2008-01-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 833 | $17.54 |
| 2008-01-22 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 178 | $0.00 |
| 2008-01-22 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 521 | $0.00 |
| 2008-01-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 65 | $36.70 |
| 2008-01-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 299 | $36.48 |
| 2008-01-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 299 | $36.35 |
| 2008-01-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 299 | $36.32 |
| 2008-01-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | ストックオプション | 売却 | 12,500 | $0.00 |
| 2008-01-02 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 100 | $36.30 |
| 2008-01-02 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 400 | $36.31 |
| 2008-01-02 | ASELAGE, STEVE | SVP, Global Commercial Dev | ストックオプション | 売却 | 5,000 | $0.00 |
| 2008-01-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $36.09 |
| 2008-01-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 500 | $36.10 |
| 2008-01-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,200 | $36.13 |
| 2008-01-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 300 | $36.15 |
| 2008-01-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,500 | $36.18 |
| 2008-01-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,500 | $36.30 |
| 2008-01-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 900 | $36.34 |
| 2008-01-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 600 | $36.36 |
| 2008-01-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,500 | $35.28 |
| 2008-01-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 500 | $35.95 |
| 2008-01-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,100 | $36.40 |
| 2008-01-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 400 | $36.42 |
| 2008-01-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 15,000 | $0.00 |
| 2008-01-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 購入 | 12,500 | $6.13 |
| 2008-01-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 642 | $35.96 |
| 2008-01-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 100 | $35.97 |
| 2008-01-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 500 | $35.99 |
| 2008-01-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 750 | $36.00 |
| 2008-01-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 400 | $36.00 |
| 2008-01-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 100 | $36.00 |
| 2008-01-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 8 | $36.05 |
| 2008-01-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 150 | $36.10 |
| 2008-01-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,100 | $36.11 |
| 2008-01-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,250 | $36.14 |
| 2008-01-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,250 | $36.18 |
| 2008-01-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 40 | $36.32 |
| 2008-01-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 209 | $36.48 |
| 2008-01-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 300 | $36.49 |
| 2008-01-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,250 | $36.03 |
| 2008-01-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 300 | $36.38 |
| 2008-01-02 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 購入 | 5,000 | $7.16 |
| 2008-01-02 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 200 | $35.97 |
| 2008-01-02 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 300 | $35.97 |
| 2008-01-02 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 200 | $35.98 |
| 2008-01-02 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 300 | $35.99 |
| 2008-01-02 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 100 | $36.12 |
| 2008-01-02 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 500 | $36.13 |
| 2008-01-02 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 500 | $36.18 |
| 2008-01-02 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 260 | $36.31 |
| 2008-01-02 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 240 | $36.32 |
| 2008-01-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 567 | $35.99 |
| 2008-01-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 733 | $36.00 |
| 2008-01-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $35.94 |
| 2008-01-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 470 | $36.30 |
| 2008-01-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 740 | $36.31 |
| 2008-01-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 441 | $36.50 |
| 2008-01-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 300 | $36.51 |
| 2008-01-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,250 | $35.28 |
| 2008-01-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 750 | $36.31 |
| 2008-01-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 200 | $36.35 |
| 2008-01-02 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 400 | $36.11 |
| 2008-01-02 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 500 | $36.48 |
| 2008-01-02 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 500 | $35.28 |
| 2008-01-02 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 300 | $36.03 |
| 2008-01-02 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 200 | $36.04 |
| 2008-01-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 15,000 | $6.46 |
| 2008-01-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,500 | $35.97 |
| 2008-01-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 200 | $36.01 |
| 2007-12-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 607 | $36.12 |
| 2007-12-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 606 | $36.19 |
| 2007-12-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 606 | $36.23 |
| 2007-12-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 60 | $36.20 |
| 2007-12-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 520 | $0.00 |
| 2007-12-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 177 | $0.00 |
| 2007-12-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 521 | $0.00 |
| 2007-12-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 313 | $0.00 |
| 2007-12-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 833 | $0.00 |
| 2007-12-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 3,750 | $0.00 |
| 2007-12-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 600 | $36.04 |
| 2007-12-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 606 | $35.82 |
| 2007-12-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 833 | $17.54 |
| 2007-12-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 313 | $14.00 |
| 2007-12-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 521 | $11.74 |
| 2007-12-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 177 | $6.13 |
| 2007-12-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 520 | $6.37 |
| 2007-12-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 811 | $36.09 |
| 2007-12-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 200 | $36.10 |
| 2007-12-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 3,750 | $17.33 |
| 2007-12-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 200 | $36.11 |
| 2007-12-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 607 | $36.11 |
| 2007-12-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 606 | $36.06 |
| 2007-12-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 605 | $35.83 |
| 2007-12-17 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,125 | $35.92 |
| 2007-12-17 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 15,000 | $0.00 |
| 2007-12-17 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 売却 | 10,000 | $0.00 |
| 2007-12-17 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 15,000 | $6.46 |
| 2007-12-17 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,500 | $35.15 |
| 2007-12-17 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,500 | $35.28 |
| 2007-12-17 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,310 | $35.43 |
| 2007-12-17 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 190 | $35.44 |
| 2007-12-17 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 100 | $35.49 |
| 2007-12-17 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,400 | $35.49 |
| 2007-12-17 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,500 | $35.54 |
| 2007-12-17 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,500 | $35.67 |
| 2007-12-17 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,500 | $35.67 |
| 2007-12-17 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,500 | $35.40 |
| 2007-12-17 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,500 | $35.81 |
| 2007-12-17 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 375 | $35.64 |
| 2007-11-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 153 | $25.93 |
| 2007-11-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 4 | $25.97 |
| 2007-11-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 153 | $25.98 |
| 2007-11-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 521 | $11.74 |
| 2007-11-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 177 | $6.13 |
| 2007-11-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 521 | $6.37 |
| 2007-11-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 834 | $0.00 |
| 2007-11-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 312 | $0.00 |
| 2007-11-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 177 | $0.00 |
| 2007-11-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 521 | $0.00 |
| 2007-11-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 834 | $26.00 |
| 2007-11-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 153 | $25.71 |
| 2007-11-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 312 | $14.00 |
| 2007-11-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 153 | $25.61 |
| 2007-11-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 154 | $25.70 |
| 2007-11-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 153 | $25.80 |
| 2007-11-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 153 | $26.03 |
| 2007-11-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 834 | $17.54 |
| 2007-11-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 153 | $25.27 |
| 2007-11-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 153 | $25.84 |
| 2007-11-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 149 | $25.94 |
| 2007-10-31 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 購入 | 2,038 | $6.92 |
| 2007-10-31 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 購入 | 2,139 | $6.92 |
| 2007-10-31 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 518 | $6.92 |
| 2007-10-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 833 | $17.54 |
| 2007-10-24 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 833 | $0.00 |
| 2007-10-24 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 833 | $26.00 |
| 2007-10-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 306 | $25.31 |
| 2007-10-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 153 | $25.33 |
| 2007-10-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 154 | $25.36 |
| 2007-10-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 153 | $25.37 |
| 2007-10-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 153 | $25.39 |
| 2007-10-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 521 | $11.74 |
| 2007-10-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 153 | $25.46 |
| 2007-10-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 177 | $6.13 |
| 2007-10-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 521 | $0.00 |
| 2007-10-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 177 | $0.00 |
| 2007-10-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 313 | $0.00 |
| 2007-10-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 153 | $25.19 |
| 2007-10-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 153 | $25.30 |
| 2007-10-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 521 | $6.37 |
| 2007-10-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 313 | $14.00 |
| 2007-10-22 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 154 | $25.00 |
| 2007-10-11 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 5,000 | $27.34 |
| 2007-10-11 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 購入 | 5,000 | $8.05 |
| 2007-10-11 | DAVIS, GEORGE ERIC | VP, General Counsel | ストックオプション | 売却 | 5,000 | $0.00 |
| 2007-10-08 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 12,380 | $8.10 |
| 2007-10-08 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 12,380 | $0.00 |
| 2007-10-08 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 8,333 | $26.00 |
| 2007-10-08 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 8,333 | $17.54 |
| 2007-10-08 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 8,333 | $0.00 |
| 2007-10-08 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 12,380 | $26.00 |
| 2007-10-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,250 | $24.99 |
| 2007-10-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 購入 | 10,000 | $6.13 |
| 2007-10-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,202 | $24.90 |
| 2007-10-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 購入 | 2,500 | $4.00 |
| 2007-10-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 48 | $24.91 |
| 2007-10-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 644 | $25.00 |
| 2007-10-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,250 | $25.22 |
| 2007-10-01 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 5,000 | $25.10 |
| 2007-10-01 | DAVIS, GEORGE ERIC | VP, General Counsel | ストックオプション | 売却 | 5,000 | $0.00 |
| 2007-10-01 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 購入 | 5,000 | $7.16 |
| 2007-10-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 100 | $25.00 |
| 2007-10-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,250 | $25.08 |
| 2007-10-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,756 | $25.10 |
| 2007-10-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,250 | $25.11 |
| 2007-10-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,250 | $25.13 |
| 2007-10-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,250 | $25.14 |
| 2007-10-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,250 | $25.30 |
| 2007-10-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | ストックオプション | 売却 | 2,500 | $0.00 |
| 2007-10-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | ストックオプション | 売却 | 10,000 | $0.00 |
| 2007-10-01 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 購入 | 5,000 | $6.13 |
| 2007-10-01 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 500 | $24.90 |
| 2007-10-01 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 500 | $25.00 |
| 2007-10-01 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 400 | $25.05 |
| 2007-10-01 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 500 | $25.05 |
| 2007-10-01 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 100 | $25.06 |
| 2007-10-01 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 500 | $25.07 |
| 2007-10-01 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 500 | $25.10 |
| 2007-10-01 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 500 | $25.14 |
| 2007-10-01 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 500 | $25.15 |
| 2007-10-01 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 500 | $25.20 |
| 2007-10-01 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 500 | $25.28 |
| 2007-10-01 | ASELAGE, STEVE | SVP, Global Commercial Dev | ストックオプション | 売却 | 5,000 | $0.00 |
| 2007-10-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 793 | $6.46 |
| 2007-10-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 793 | $25.10 |
| 2007-10-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 793 | $0.00 |
| 2007-09-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 19,207 | $0.00 |
| 2007-09-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 19,207 | $25.00 |
| 2007-09-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 19,207 | $6.46 |
| 2007-09-26 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 12,500 | $8.10 |
| 2007-09-26 | COOPER, JEFFREY H | SVP, Chief Financial Officer | ストックオプション | 売却 | 12,500 | $0.00 |
| 2007-09-26 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 12,500 | $24.50 |
| 2007-09-25 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $24.00 |
| 2007-09-25 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $6.46 |
| 2007-09-25 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 10,000 | $0.00 |
| 2007-09-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 590 | $23.46 |
| 2007-09-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 521 | $0.00 |
| 2007-09-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 177 | $0.00 |
| 2007-09-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 590 | $23.11 |
| 2007-09-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 291 | $23.19 |
| 2007-09-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 300 | $23.20 |
| 2007-09-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 100 | $23.27 |
| 2007-09-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 981 | $23.28 |
| 2007-09-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 690 | $23.30 |
| 2007-09-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 1,082 | $23.34 |
| 2007-09-21 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 4,687 | $0.00 |
| 2007-09-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 100 | $23.33 |
| 2007-09-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 4,687 | $14.00 |
| 2007-09-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 591 | $23.00 |
| 2007-09-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 591 | $23.18 |
| 2007-09-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 521 | $6.37 |
| 2007-09-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 177 | $6.13 |
| 2007-09-21 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 521 | $11.74 |
| 2007-09-19 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 10,000 | $0.00 |
| 2007-09-19 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $23.00 |
| 2007-09-19 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $6.46 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 3,852 | $22.45 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 3,700 | $22.55 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 5,507 | $22.61 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 3,619 | $22.62 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 3,890 | $22.63 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 2,349 | $22.64 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 3,251 | $22.65 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,200 | $22.66 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 700 | $22.67 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $22.72 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $22.68 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 800 | $22.69 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 500 | $22.70 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 591 | $22.71 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 5,000 | $22.50 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 200 | $22.51 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 900 | $22.53 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 2,700 | $22.57 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 4,000 | $22.58 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 900 | $22.59 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 5,693 | $22.60 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | ストックオプション | 売却 | 90,000 | $0.00 |
| 2007-09-14 | ASELAGE, STEVE | SVP, Global Commercial Dev. | 普通株式 | 購入 | 10,000 | $7.16 |
| 2007-09-14 | ASELAGE, STEVE | SVP, Global Commercial Dev. | 普通株式 | 売却 | 10,000 | $22.40 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 500 | $22.52 |
| 2007-09-14 | ASELAGE, STEVE | SVP, Global Commercial Dev. | ストックオプション | 売却 | 10,000 | $0.00 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 3,500 | $22.54 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 購入 | 90,000 | $6.13 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $22.34 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 2,800 | $22.35 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,150 | $22.36 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 2,550 | $22.37 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 4,450 | $22.38 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 500 | $22.39 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 2,776 | $22.40 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 996 | $22.41 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,628 | $22.42 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,100 | $22.43 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 3,500 | $22.44 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 300 | $22.45 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,000 | $22.56 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 100 | $22.46 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 3,600 | $22.46 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 3,501 | $22.47 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 4,597 | $22.48 |
| 2007-09-14 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 売却 | 1,500 | $22.49 |
| 2007-09-06 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 13,536 | $22.50 |
| 2007-09-06 | COOPER, JEFFREY H | SVP, Chief Financial Officer | ストックオプション | 売却 | 13,536 | $0.00 |
| 2007-09-06 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 13,536 | $8.10 |
| 2007-08-17 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 10,000 | $21.00 |
| 2007-08-17 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 8,958 | $7.76 |
| 2007-08-17 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 6,751 | $6.13 |
| 2007-08-17 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 1,500 | $20.12 |
| 2007-08-17 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 644 | $20.13 |
| 2007-08-17 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 200 | $20.14 |
| 2007-08-17 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 100 | $20.15 |
| 2007-08-17 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 100 | $20.18 |
| 2007-08-17 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 4,291 | $5.15 |
| 2007-08-17 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 100 | $20.23 |
| 2007-08-17 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 200 | $20.25 |
| 2007-08-17 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 2,286 | $20.26 |
| 2007-08-17 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 4,854 | $20.27 |
| 2007-08-17 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 4,800 | $20.28 |
| 2007-08-17 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 616 | $20.29 |
| 2007-08-17 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 1,000 | $20.35 |
| 2007-08-17 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 500 | $20.36 |
| 2007-08-17 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 900 | $20.37 |
| 2007-08-17 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 2,000 | $20.46 |
| 2007-08-17 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 100 | $20.47 |
| 2007-08-17 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 100 | $20.50 |
| 2007-08-17 | COOPER, JEFFREY H | SVP, Chief Financial Officer | ストックオプション | 売却 | 8,958 | $0.00 |
| 2007-08-17 | COOPER, JEFFREY H | SVP, Chief Financial Officer | ストックオプション | 売却 | 4,291 | $0.00 |
| 2007-08-17 | COOPER, JEFFREY H | SVP, Chief Financial Officer | ストックオプション | 売却 | 6,751 | $0.00 |
| 2007-08-17 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $6.46 |
| 2007-08-17 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 10,000 | $0.00 |
| 2007-08-15 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 4,000 | $20.26 |
| 2007-08-15 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 購入 | 4,000 | $6.13 |
| 2007-08-15 | DAVIS, GEORGE ERIC | VP, General Counsel | ストックオプション | 売却 | 4,000 | $0.00 |
| 2007-08-10 | LEWIS, ALAN | Director | 普通株式 | 売却 | 1,000 | $20.09 |
| 2007-08-10 | LEWIS, ALAN | Director | 普通株式 | 売却 | 200 | $20.08 |
| 2007-08-10 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 531 | $0.00 |
| 2007-08-10 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 1,049 | $0.00 |
| 2007-08-10 | LEWIS, ALAN | Director | 普通株式 | 売却 | 100 | $20.24 |
| 2007-08-10 | LEWIS, ALAN | Director | 普通株式 | 売却 | 100 | $20.23 |
| 2007-08-10 | LEWIS, ALAN | Director | 普通株式 | 売却 | 300 | $20.21 |
| 2007-08-10 | LEWIS, ALAN | Director | 普通株式 | 売却 | 1,100 | $20.19 |
| 2007-08-10 | LEWIS, ALAN | Director | 普通株式 | 売却 | 600 | $20.15 |
| 2007-08-10 | LEWIS, ALAN | Director | 普通株式 | 売却 | 1,600 | $20.07 |
| 2007-08-10 | LEWIS, ALAN | Director | 普通株式 | 売却 | 200 | $20.03 |
| 2007-08-10 | LEWIS, ALAN | Director | 普通株式 | 売却 | 200 | $20.01 |
| 2007-08-10 | LEWIS, ALAN | Director | 普通株式 | 売却 | 8,300 | $20.00 |
| 2007-08-10 | LEWIS, ALAN | Director | 普通株式 | 売却 | 400 | $20.25 |
| 2007-08-10 | LEWIS, ALAN | Director | ストックオプション | 売却 | 30,000 | $0.00 |
| 2007-08-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 35,886 | $6.46 |
| 2007-08-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 33,886 | $20.20 |
| 2007-08-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,000 | $20.21 |
| 2007-08-10 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 35,886 | $0.00 |
| 2007-08-10 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 1,600 | $20.34 |
| 2007-08-10 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 1,053 | $0.00 |
| 2007-08-10 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 購入 | 20,000 | $7.16 |
| 2007-08-10 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 300 | $20.22 |
| 2007-08-10 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 700 | $20.23 |
| 2007-08-10 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 2,100 | $20.25 |
| 2007-08-10 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 800 | $20.30 |
| 2007-08-10 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 1,000 | $20.35 |
| 2007-08-10 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 3,400 | $20.33 |
| 2007-08-10 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 100 | $20.32 |
| 2007-08-10 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 700 | $20.36 |
| 2007-08-10 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 100 | $20.37 |
| 2007-08-10 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 7,500 | $20.21 |
| 2007-08-10 | ASELAGE, STEVE | SVP, Global Commercial Dev | ストックオプション | 売却 | 20,000 | $0.00 |
| 2007-08-10 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 1,049 | $11.74 |
| 2007-08-10 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 300 | $20.31 |
| 2007-08-10 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 200 | $20.29 |
| 2007-08-10 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 1,053 | $6.37 |
| 2007-08-10 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 531 | $6.13 |
| 2007-08-10 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 1,100 | $20.28 |
| 2007-08-10 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 売却 | 100 | $20.26 |
| 2007-08-10 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 2,633 | $21.08 |
| 2007-08-10 | LEWIS, ALAN | Director | 普通株式 | 購入 | 30,000 | $7.72 |
| 2007-08-10 | LEWIS, ALAN | Director | 普通株式 | 売却 | 1,500 | $20.18 |
| 2007-08-10 | LEWIS, ALAN | Director | 普通株式 | 売却 | 600 | $20.17 |
| 2007-08-10 | LEWIS, ALAN | Director | 普通株式 | 売却 | 1,000 | $20.16 |
| 2007-08-10 | LEWIS, ALAN | Director | 普通株式 | 売却 | 800 | $20.14 |
| 2007-08-10 | LEWIS, ALAN | Director | 普通株式 | 売却 | 1,600 | $20.13 |
| 2007-08-10 | LEWIS, ALAN | Director | 普通株式 | 売却 | 200 | $20.12 |
| 2007-08-10 | LEWIS, ALAN | Director | 普通株式 | 売却 | 200 | $20.11 |
| 2007-08-08 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 売却 | 12,500 | $21.00 |
| 2007-08-08 | COOPER, JEFFREY H | SVP, Chief Financial Officer | 普通株式 | 購入 | 12,500 | $8.10 |
| 2007-08-08 | COOPER, JEFFREY H | SVP, Chief Financial Officer | ストックオプション | 売却 | 12,500 | $0.00 |
| 2007-08-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 600 | $18.04 |
| 2007-08-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 300 | $18.05 |
| 2007-08-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 400 | $18.02 |
| 2007-08-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 600 | $18.01 |
| 2007-08-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 100 | $18.00 |
| 2007-07-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $18.31 |
| 2007-07-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 500 | $18.21 |
| 2007-07-05 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 500 | $18.33 |
| 2007-07-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 600 | $18.15 |
| 2007-07-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,750 | $18.16 |
| 2007-07-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 900 | $18.17 |
| 2007-07-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,250 | $18.09 |
| 2007-07-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 300 | $18.15 |
| 2007-07-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 200 | $18.16 |
| 2007-07-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,100 | $18.18 |
| 2007-07-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 400 | $18.20 |
| 2007-07-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 450 | $18.20 |
| 2007-07-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 100 | $18.26 |
| 2007-07-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 100 | $18.27 |
| 2007-07-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 購入 | 12,500 | $4.00 |
| 2007-07-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,150 | $18.27 |
| 2007-07-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 400 | $18.21 |
| 2007-07-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 200 | $18.19 |
| 2007-07-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 450 | $18.18 |
| 2007-07-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,150 | $18.26 |
| 2007-07-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | ストックオプション | 売却 | 12,500 | $0.00 |
| 2007-07-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 100 | $18.12 |
| 2007-07-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,150 | $18.12 |
| 2007-07-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 450 | $18.13 |
| 2007-07-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 300 | $18.14 |
| 2007-06-25 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 2,500 | $17.65 |
| 2007-06-07 | DAVIS, GEORGE ERIC | VP, General Counsel | ストックオプション | 購入 | 45,000 | $17.33 |
| 2007-06-07 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 514 | $6.37 |
| 2007-06-07 | WOOD, MARK | VP, Human Resources | ストックオプション | 購入 | 30,000 | $17.33 |
| 2007-06-07 | ASELAGE, STEVE | SVP, Global Commercial Ops | ストックオプション | 購入 | 70,000 | $17.33 |
| 2007-06-07 | ASELAGE, STEVE | SVP, Global Commercial Ops | 譲渡制限付株式ユニット | 購入 | 10,000 | $0.00 |
| 2007-06-07 | COOPER, JEFFREY H | Chief Financial Officer | ストックオプション | 購入 | 60,000 | $17.33 |
| 2007-06-07 | COOPER, JEFFREY H | Chief Financial Officer | 譲渡制限付株式ユニット | 購入 | 8,000 | $0.00 |
| 2007-06-07 | DAVIS, GEORGE ERIC | VP, General Counsel | 譲渡制限付株式ユニット | 購入 | 6,000 | $0.00 |
| 2007-06-07 | WOOD, MARK | VP, Human Resources | 譲渡制限付株式ユニット | 売却 | 4,000 | $0.00 |
| 2007-06-07 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 520 | $0.00 |
| 2007-06-07 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 11 | $0.00 |
| 2007-06-07 | WOOD, MARK | VP, Human Resources | ストックオプション | 売却 | 514 | $0.00 |
| 2007-06-07 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 11 | $6.13 |
| 2007-06-07 | HERON, ELAINE J | Director | 譲渡制限付株式ユニット | 購入 | 2,500 | $0.00 |
| 2007-06-07 | LEWIS, ALAN | Director | ストックオプション | 購入 | 15,000 | $17.33 |
| 2007-06-07 | WOOD, MARK | VP, Human Resources | 普通株式 | 売却 | 1,045 | $17.54 |
| 2007-06-07 | WOOD, MARK | VP, Human Resources | 普通株式 | 購入 | 520 | $11.74 |
| 2007-06-07 | MEIER, RICHARD A | Director | ストックオプション | 購入 | 7,500 | $17.33 |
| 2007-06-07 | MEIER, RICHARD A | Director | 譲渡制限付株式ユニット | 購入 | 1,250 | $0.00 |
| 2007-06-07 | GREY, MICHAEL G | Director | ストックオプション | 購入 | 7,500 | $17.33 |
| 2007-06-07 | GREY, MICHAEL G | Director | 譲渡制限付株式ユニット | 購入 | 1,250 | $0.00 |
| 2007-06-07 | LAPALME, PIERRE | Director | ストックオプション | 購入 | 22,500 | $17.33 |
| 2007-06-07 | LAPALME, PIERRE | Director | 譲渡制限付株式ユニット | 購入 | 3,750 | $0.00 |
| 2007-06-07 | LEWIS, ALAN | Director | 譲渡制限付株式ユニット | 購入 | 2,500 | $0.00 |
| 2007-06-07 | HERON, ELAINE J | Director | ストックオプション | 購入 | 15,000 | $17.33 |
| 2007-06-07 | KLEIN, JOSEPH III | Director | ストックオプション | 購入 | 15,000 | $17.33 |
| 2007-06-07 | KLEIN, JOSEPH III | Director | 譲渡制限付株式ユニット | 購入 | 2,500 | $0.00 |
| 2007-06-07 | LAWLIS, V BRYAN | Director | ストックオプション | 売却 | 30,000 | $0.00 |
| 2007-06-07 | SWIEDLER, STUART J | SVP, Clinical Affairs | ストックオプション | 購入 | 60,000 | $17.33 |
| 2007-06-07 | SWIEDLER, STUART J | SVP, Clinical Affairs | 譲渡制限付株式ユニット | 購入 | 8,000 | $0.00 |
| 2007-06-07 | KAKKIS, EMIL D | Chief Medical Officer | ストックオプション | 購入 | 70,000 | $17.33 |
| 2007-06-07 | KAKKIS, EMIL D | Chief Medical Officer | 譲渡制限付株式ユニット | 購入 | 10,000 | $0.00 |
| 2007-06-07 | BAFFI, ROBERT | SVP, Technical Operations | ストックオプション | 購入 | 60,000 | $17.33 |
| 2007-06-07 | BAFFI, ROBERT | SVP, Technical Operations | 譲渡制限付株式ユニット | 購入 | 8,000 | $0.00 |
| 2007-06-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 譲渡制限付株式ユニット | 購入 | 20,000 | $0.00 |
| 2007-06-07 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 購入 | 160,000 | $0.00 |
| 2007-06-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 500 | $18.40 |
| 2007-06-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 200 | $18.39 |
| 2007-06-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,800 | $18.38 |
| 2007-06-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,800 | $18.35 |
| 2007-06-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 200 | $18.35 |
| 2007-06-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $18.33 |
| 2007-06-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 10,000 | $6.46 |
| 2007-06-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 900 | $18.26 |
| 2007-06-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 400 | $18.25 |
| 2007-06-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 10,000 | $0.00 |
| 2007-06-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 100 | $18.18 |
| 2007-06-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 900 | $18.37 |
| 2007-06-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 100 | $18.37 |
| 2007-06-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 700 | $18.40 |
| 2007-06-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 900 | $18.18 |
| 2007-06-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 700 | $18.26 |
| 2007-06-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 900 | $18.38 |
| 2007-06-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 100 | $18.38 |
| 2007-06-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 900 | $18.41 |
| 2007-06-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 100 | $18.41 |
| 2007-06-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 300 | $18.40 |
| 2007-05-21 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 900 | $18.58 |
| 2007-05-21 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 100 | $18.54 |
| 2007-05-21 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 900 | $18.54 |
| 2007-05-21 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 100 | $18.58 |
| 2007-05-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 400 | $16.85 |
| 2007-05-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,400 | $16.78 |
| 2007-05-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $16.80 |
| 2007-05-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 600 | $16.80 |
| 2007-05-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,400 | $16.85 |
| 2007-05-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 700 | $16.86 |
| 2007-05-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 1,500 | $0.00 |
| 2007-05-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 15,000 | $6.46 |
| 2007-05-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 100 | $16.70 |
| 2007-05-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 500 | $16.75 |
| 2007-05-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,400 | $16.70 |
| 2007-05-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,400 | $16.73 |
| 2007-05-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 100 | $16.74 |
| 2007-05-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 700 | $16.75 |
| 2007-05-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,300 | $16.76 |
| 2007-05-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 500 | $16.76 |
| 2007-05-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 100 | $16.78 |
| 2007-05-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 582 | $16.81 |
| 2007-05-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 400 | $16.81 |
| 2007-05-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 418 | $16.82 |
| 2007-05-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,500 | $16.83 |
| 2007-05-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 500 | $16.84 |
| 2007-05-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 500 | $16.44 |
| 2007-05-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 500 | $16.36 |
| 2007-05-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 500 | $16.49 |
| 2007-04-30 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 購入 | 2,607 | $5.19 |
| 2007-04-30 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 購入 | 2,684 | $5.19 |
| 2007-04-30 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 2,553 | $6.92 |
| 2007-04-30 | ASELAGE, STEVE | SVP, Global Commercial Dev | 普通株式 | 購入 | 2,066 | $6.92 |
| 2007-04-30 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 購入 | 2,982 | $5.19 |
| 2007-04-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 500 | $17.85 |
| 2007-04-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 500 | $17.83 |
| 2007-04-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 400 | $17.72 |
| 2007-04-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 100 | $17.89 |
| 2007-04-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 400 | $17.89 |
| 2007-04-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 100 | $17.90 |
| 2007-04-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 100 | $17.94 |
| 2007-04-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 400 | $17.94 |
| 2007-04-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 100 | $17.95 |
| 2007-04-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 400 | $17.95 |
| 2007-04-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 200 | $17.96 |
| 2007-04-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 800 | $17.96 |
| 2007-04-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 100 | $17.70 |
| 2007-04-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 400 | $17.70 |
| 2007-04-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 500 | $17.80 |
| 2007-04-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2007-04-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 200 | $17.91 |
| 2007-04-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 400 | $17.90 |
| 2007-04-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $6.46 |
| 2007-04-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 100 | $17.71 |
| 2007-04-04 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 800 | $17.91 |
| 2007-04-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 500 | $17.23 |
| 2007-04-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 購入 | 12,500 | $4.00 |
| 2007-04-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 500 | $17.18 |
| 2007-04-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 750 | $17.18 |
| 2007-04-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 400 | $17.26 |
| 2007-04-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 500 | $17.41 |
| 2007-04-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 350 | $17.40 |
| 2007-04-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 900 | $17.40 |
| 2007-04-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 800 | $17.38 |
| 2007-04-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 450 | $17.37 |
| 2007-04-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,250 | $17.37 |
| 2007-04-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,500 | $17.29 |
| 2007-04-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 1,000 | $17.29 |
| 2007-04-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | ストックオプション | 売却 | 12,500 | $0.00 |
| 2007-04-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 750 | $17.41 |
| 2007-04-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 350 | $17.25 |
| 2007-04-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 500 | $17.25 |
| 2007-04-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 750 | $17.24 |
| 2007-04-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 500 | $17.24 |
| 2007-04-02 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 750 | $17.23 |
| 2007-03-07 | KLEIN, JOSEPH III | Director | 普通株式 | 売却 | 300 | $16.36 |
| 2007-03-07 | KLEIN, JOSEPH III | Director | 普通株式 | 売却 | 7,800 | $16.36 |
| 2007-03-07 | KLEIN, JOSEPH III | Director | 普通株式 | 売却 | 900 | $16.37 |
| 2007-03-07 | KLEIN, JOSEPH III | Director | 普通株式 | 売却 | 800 | $16.39 |
| 2007-03-07 | KLEIN, JOSEPH III | Director | 普通株式 | 売却 | 2,200 | $16.38 |
| 2007-03-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 500 | $16.56 |
| 2007-03-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 700 | $16.44 |
| 2007-03-02 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 300 | $16.45 |
| 2007-02-22 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 1,000 | $18.40 |
| 2007-02-22 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 2,284 | $18.39 |
| 2007-02-22 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 購入 | 13,000 | $6.13 |
| 2007-02-22 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 900 | $18.38 |
| 2007-02-22 | DAVIS, GEORGE ERIC | VP, General Counsel | ストックオプション | 売却 | 13,000 | $0.00 |
| 2007-02-22 | DAVIS, GEORGE ERIC | VP, General Counsel | 普通株式 | 売却 | 9,816 | $18.37 |
| 2007-02-20 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 売却 | 13,000 | $16.96 |
| 2007-02-14 | ASELAGE, STEVE | SVP, Global Commercial Ops | 普通株式 | 購入 | 15,000 | $7.16 |
| 2007-02-14 | ASELAGE, STEVE | SVP, Global Commercial Ops | ストックオプション | 売却 | 15,000 | $0.00 |
| 2007-02-14 | ASELAGE, STEVE | SVP, Global Commercial Ops | 普通株式 | 売却 | 15,000 | $20.00 |
| 2007-01-04 | KAKKIS, EMIL D | Chief Medical Officer | ストックオプション | 売却 | 50,000 | $0.00 |
| 2007-01-03 | SWIEDLER, STUART J | SVP, Clinical Affairs | ストックオプション | 売却 | 12,500 | $0.00 |
| 2007-01-03 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 購入 | 12,500 | $4.00 |
| 2007-01-03 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 12,500 | $16.30 |
| 2006-12-14 | MEIER, RICHARD A | Director | ストックオプション | 購入 | 30,000 | $0.00 |
| 2006-12-14 | GREY, MICHAEL G | Director | ストックオプション | 購入 | 30,000 | $0.00 |
| 2006-12-12 | LAPALME, PIERRE | Director | 普通株式 | 購入 | 1,100 | $17.89 |
| 2006-12-12 | LAPALME, PIERRE | Director | 普通株式 | 購入 | 1,000 | $17.88 |
| 2006-12-06 | COOPER, JEFFREY H | Chief Financial Officer | ストックオプション | 売却 | 14,500 | $0.00 |
| 2006-12-06 | COOPER, JEFFREY H | Chief Financial Officer | 普通株式 | 購入 | 14,500 | $8.10 |
| 2006-12-06 | COOPER, JEFFREY H | Chief Financial Officer | 普通株式 | 売却 | 14,500 | $18.00 |
| 2006-11-29 | ASELAGE, STEVE | SVP, Global Commercial Ops | 普通株式 | 売却 | 5,000 | $17.23 |
| 2006-11-29 | ASELAGE, STEVE | SVP, Global Commercial Ops | 普通株式 | 購入 | 5,000 | $7.16 |
| 2006-11-29 | ASELAGE, STEVE | SVP, Global Commercial Ops | ストックオプション | 売却 | 5,000 | $0.00 |
| 2006-11-20 | SWIEDLER, STUART J | SVP, Clinical Affairs | ストックオプション | 購入 | 80,000 | $0.00 |
| 2006-11-20 | DAVIS, GEORGE ERIC | VP, General Counsel | ストックオプション | 購入 | 60,000 | $0.00 |
| 2006-11-20 | BAFFI, ROBERT | SVP, Technical Operations | ストックオプション | 購入 | 90,000 | $0.00 |
| 2006-11-20 | ASELAGE, STEVE | SVP, Global Commercial Ops | ストックオプション | 購入 | 100,000 | $0.00 |
| 2006-11-20 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 購入 | 250,000 | $0.00 |
| 2006-11-20 | COOPER, JEFFREY H | Chief Financial Officer | ストックオプション | 購入 | 60,000 | $0.00 |
| 2006-11-20 | KAKKIS, EMIL D | Chief Medical Officer | ストックオプション | 購入 | 100,000 | $0.00 |
| 2006-11-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | ストックオプション | 売却 | 12,500 | $0.00 |
| 2006-11-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 12,500 | $15.92 |
| 2006-11-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 購入 | 12,500 | $4.00 |
| 2006-10-31 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 購入 | 3,894 | $3.43 |
| 2006-10-31 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 2,761 | $6.92 |
| 2006-10-31 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 購入 | 4,368 | $3.43 |
| 2006-10-31 | ASELAGE, STEVE | SVP, Global Commercial Ops | 普通株式 | 購入 | 1,870 | $6.92 |
| 2006-08-29 | COOPER, JEFFREY H | VP, Chief Financial Officer | 普通株式 | 購入 | 20,000 | $8.10 |
| 2006-08-29 | COOPER, JEFFREY H | VP, Chief Financial Officer | ストックオプション | 売却 | 6,000 | $0.00 |
| 2006-08-29 | COOPER, JEFFREY H | VP, Chief Financial Officer | ストックオプション | 売却 | 20,000 | $0.00 |
| 2006-08-29 | COOPER, JEFFREY H | VP, Chief Financial Officer | 普通株式 | 売却 | 6,000 | $16.00 |
| 2006-08-29 | COOPER, JEFFREY H | VP, Chief Financial Officer | 普通株式 | 売却 | 20,000 | $16.00 |
| 2006-08-29 | COOPER, JEFFREY H | VP, Chief Financial Officer | 普通株式 | 購入 | 6,000 | $6.13 |
| 2006-08-09 | KLEIN, JOSEPH III | Director | 普通株式 | 売却 | 20,000 | $15.52 |
| 2006-08-09 | KLEIN, JOSEPH III | Director | ストックオプション | 売却 | 30,000 | $0.00 |
| 2006-08-09 | KLEIN, JOSEPH III | Director | 普通株式 | 購入 | 30,000 | $7.72 |
| 2006-08-07 | LAPALME, PIERRE | Director | 普通株式 | 購入 | 1,000 | $15.35 |
| 2006-08-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,500 | $14.50 |
| 2006-08-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 購入 | 12,500 | $4.00 |
| 2006-08-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 12,500 | $14.34 |
| 2006-08-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | ストックオプション | 売却 | 12,500 | $0.00 |
| 2006-07-19 | HERON, ELAINE J | Director | ストックオプション | 売却 | 20,000 | $0.00 |
| 2006-07-19 | HERON, ELAINE J | Director | 普通株式 | 購入 | 20,000 | $4.72 |
| 2006-07-12 | HERON, ELAINE J | Director | ストックオプション | 購入 | 30,000 | $0.00 |
| 2006-07-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 500 | $14.44 |
| 2006-07-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $14.44 |
| 2006-06-28 | LEWIS, ALAN | Director | ストックオプション | 購入 | 30,000 | $0.00 |
| 2006-06-28 | KLEIN, JOSEPH III | Director | ストックオプション | 購入 | 30,000 | $0.00 |
| 2006-06-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 500 | $13.20 |
| 2006-06-14 | CRISTIANI, FRANZ L | Director | ストックオプション | 購入 | 30,000 | $0.00 |
| 2006-06-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 500 | $13.15 |
| 2006-06-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 500 | $13.23 |
| 2006-06-14 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $13.30 |
| 2006-06-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,500 | $13.05 |
| 2006-05-18 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $12.00 |
| 2006-05-11 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 購入 | 250,000 | $0.00 |
| 2006-05-11 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 購入 | 162,500 | $0.00 |
| 2006-05-08 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $12.78 |
| 2006-05-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 500 | $12.55 |
| 2006-05-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 500 | $12.65 |
| 2006-05-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 500 | $12.56 |
| 2006-04-28 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 購入 | 3,797 | $3.43 |
| 2006-04-28 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 3,381 | $6.92 |
| 2006-04-28 | ASELAGE, STEVE | SVP, Global Commercial Ops | 普通株式 | 購入 | 959 | $6.92 |
| 2006-04-28 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 購入 | 4,202 | $3.43 |
| 2006-04-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,200 | $13.35 |
| 2006-04-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 300 | $13.33 |
| 2006-03-16 | COOPER, JEFFREY H | Chief Financial Officer | 普通株式 | 購入 | 12,500 | $8.10 |
| 2006-03-16 | COOPER, JEFFREY H | Chief Financial Officer | 普通株式 | 売却 | 12,500 | $14.85 |
| 2006-03-16 | COOPER, JEFFREY H | Chief Financial Officer | ストックオプション | 売却 | 12,500 | $0.00 |
| 2006-03-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 500 | $13.00 |
| 2006-03-01 | COOPER, JEFFREY H | Chief Financial Officer | ストックオプション | 売却 | 13,500 | $0.00 |
| 2006-03-01 | COOPER, JEFFREY H | Chief Financial Officer | 普通株式 | 売却 | 13,500 | $13.25 |
| 2006-03-01 | COOPER, JEFFREY H | Chief Financial Officer | 普通株式 | 売却 | 2,000 | $13.25 |
| 2006-03-01 | COOPER, JEFFREY H | Chief Financial Officer | 普通株式 | 購入 | 2,000 | $5.15 |
| 2006-03-01 | COOPER, JEFFREY H | Chief Financial Officer | 普通株式 | 購入 | 13,500 | $6.13 |
| 2006-03-01 | COOPER, JEFFREY H | Chief Financial Officer | ストックオプション | 売却 | 2,000 | $0.00 |
| 2006-03-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 500 | $12.96 |
| 2006-03-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 500 | $13.02 |
| 2006-02-27 | COOPER, JEFFREY H | Chief Financial Officer | ストックオプション | 売却 | 1,000 | $0.00 |
| 2006-02-27 | LAPALME, PIERRE | Director | 普通株式 | 購入 | 1,200 | $12.97 |
| 2006-02-27 | COOPER, JEFFREY H | Chief Financial Officer | 普通株式 | 購入 | 1,000 | $5.15 |
| 2006-02-27 | LAPALME, PIERRE | Director | 普通株式 | 購入 | 400 | $12.98 |
| 2006-02-27 | LAPALME, PIERRE | Director | 普通株式 | 購入 | 1,900 | $13.00 |
| 2006-02-27 | COOPER, JEFFREY H | Chief Financial Officer | 普通株式 | 売却 | 1,000 | $13.25 |
| 2006-02-24 | SAGER, ERICH | Director | 普通株式 | 購入 | 11,500 | $7.00 |
| 2006-02-24 | SAGER, ERICH | Director | 普通株式 | 売却 | 11,500 | $12.64 |
| 2006-02-24 | SAGER, ERICH | Director | ストックオプション | 売却 | 11,500 | $0.00 |
| 2006-02-22 | SAGER, ERICH | Director | 普通株式 | 購入 | 1,000 | $7.00 |
| 2006-02-22 | SAGER, ERICH | Director | ストックオプション | 売却 | 1,000 | $0.00 |
| 2006-02-22 | SAGER, ERICH | Director | 普通株式 | 売却 | 1,000 | $12.20 |
| 2006-02-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 500 | $11.65 |
| 2006-02-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 500 | $11.62 |
| 2006-02-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 500 | $11.73 |
| 2006-02-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | ストックオプション | 売却 | 10,000 | $0.00 |
| 2006-02-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 10,000 | $11.55 |
| 2006-02-01 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 購入 | 10,000 | $4.00 |
| 2006-01-27 | SAGER, ERICH | Director | 普通株式 | 売却 | 2,500 | $12.20 |
| 2006-01-27 | SAGER, ERICH | Director | 普通株式 | 購入 | 2,500 | $7.00 |
| 2006-01-27 | LAPALME, PIERRE | Director | ストックオプション | 購入 | 30,000 | $0.00 |
| 2006-01-27 | SAGER, ERICH | Director | ストックオプション | 売却 | 2,500 | $0.00 |
| 2006-01-06 | KAKKIS, EMIL D | SVP, Chief Medical Officer | ストックオプション | 購入 | 75,000 | $0.00 |
| 2006-01-06 | COOPER, JEFFREY H | Chief Financial Officer | ストックオプション | 購入 | 60,000 | $0.00 |
| 2006-01-06 | ASELAGE, STEVE | SVP, Global Commercial Ops | ストックオプション | 購入 | 75,000 | $0.00 |
| 2006-01-06 | BAFFI, ROBERT | SVP, Commercial Operations | ストックオプション | 購入 | 75,000 | $0.00 |
| 2006-01-06 | SWIEDLER, STUART J | SVP, Clinical Affairs | ストックオプション | 購入 | 75,000 | $0.00 |
| 2006-01-04 | KAKKIS, EMIL D | Chief Medical Officer | 普通株式 | 購入 | 50,000 | $4.00 |
| 2006-01-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $10.81 |
| 2006-01-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 500 | $10.76 |
| 2005-12-14 | GREY, MICHAEL G | Director | ストックオプション | 購入 | 30,000 | $0.00 |
| 2005-12-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 500 | $10.21 |
| 2005-12-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 500 | $10.21 |
| 2005-12-05 | SAGER, ERICH | Director | ストックオプション | 売却 | 7,500 | $0.00 |
| 2005-12-05 | SAGER, ERICH | Director | 普通株式 | 売却 | 7,500 | $10.70 |
| 2005-12-01 | SAGER, ERICH | Director | ストックオプション | 売却 | 22,500 | $0.00 |
| 2005-12-01 | STARR, CHRISTOPHER M | SVP, Chief Scientific Officer | ストックオプション | 売却 | 5,571 | $0.00 |
| 2005-12-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 300 | $9.92 |
| 2005-12-01 | STARR, CHRISTOPHER M | SVP, Chief Scientific Officer | 普通株式 | 売却 | 10,571 | $10.00 |
| 2005-12-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 500 | $9.89 |
| 2005-12-01 | SAGER, ERICH | Director | 普通株式 | 売却 | 22,500 | $10.42 |
| 2005-12-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 200 | $10.05 |
| 2005-12-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 500 | $9.97 |
| 2005-11-30 | SAGER, ERICH | Director | ストックオプション | 購入 | 30,000 | $0.00 |
| 2005-11-21 | SWIEDLER, STUART J | SVP, Clinical Affairs | 普通株式 | 売却 | 30,000 | $10.00 |
| 2005-11-21 | STARR, CHRISTOPHER M | SVP, Chief Scientific Officer | ストックオプション | 購入 | 2,260 | $0.00 |
| 2005-11-21 | STARR, CHRISTOPHER M | SVP, Chief Scientific Officer | 普通株式 | 売却 | 3,311 | $10.00 |
| 2005-11-21 | STARR, CHRISTOPHER M | SVP, Chief Scientific Officer | 普通株式 | 売却 | 2,260 | $10.00 |
| 2005-11-21 | STARR, CHRISTOPHER M | SVP, Chief Scientific Officer | 普通株式 | 売却 | 5,000 | $10.00 |
| 2005-11-21 | SWIEDLER, STUART J | SVP, Clinical Affairs | ストックオプション | 売却 | 30,000 | $0.00 |
| 2005-11-21 | STARR, CHRISTOPHER M | SVP, Chief Scientific Officer | ストックオプション | 購入 | 3,311 | $0.00 |
| 2005-11-11 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 購入 | 162,500 | $0.00 |
| 2005-11-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $8.36 |
| 2005-11-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 500 | $8.38 |
| 2005-10-31 | KAKKIS, EMIL D | SVP, Chief Medical Officer | 普通株式 | 購入 | 2,572 | $3.43 |
| 2005-10-31 | BAFFI, ROBERT | SVP, Commercial Operations | 普通株式 | 購入 | 3,640 | $3.43 |
| 2005-10-12 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 500 | $7.00 |
| 2005-10-06 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 500 | $8.00 |
| 2005-10-03 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 1,500 | $8.51 |
| 2005-09-01 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | 普通株式 | 購入 | 4,500 | $8.58 |
| 2005-07-18 | KAKKIS, EMIL D | SVP, Business Operations | ストックオプション | 購入 | 20,000 | $0.00 |
| 2005-07-12 | HERON, ELAINE J | Director | ストックオプション | 購入 | 30,000 | $0.00 |
| 2005-07-01 | ASELAGE, STEVE | SVP, Global Commercial Ops | ストックオプション | 購入 | 125,000 | $0.00 |
| 2005-06-28 | KLEIN, JOSEPH III | Director | ストックオプション | 購入 | 30,000 | $0.00 |
| 2005-06-28 | LEWIS, ALAN | Director | ストックオプション | 購入 | 30,000 | $0.00 |
| 2005-06-14 | CRISTIANI, FRANZ L | Director | ストックオプション | 購入 | 30,000 | $0.00 |
| 2005-05-11 | BIENAIME, JEAN JACQUES | Director, Chief Executive Officer | ストックオプション | 購入 | 325,000 | $0.00 |
| 2005-05-02 | KAKKIS, EMIL D | SVP, Business Operations | 普通株式 | 購入 | 1,968 | $3.43 |
| 2005-05-02 | DRAPEAU, LOUIS | Chief Executive Officer | 普通株式 | 購入 | 4,004 | $3.43 |
| 2005-05-02 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 購入 | 616 | $3.43 |
| 2005-01-27 | LAPALME, PIERRE | Director | ストックオプション | 購入 | 30,000 | $0.00 |
| 2005-01-07 | DRAPEAU, LOUIS | Chief Executive Officer | ストックオプション | 購入 | 100,000 | $0.00 |
| 2005-01-07 | KAKKIS, EMIL D | SVP, Business Operations | ストックオプション | 購入 | 100,000 | $0.00 |
| 2005-01-07 | STARR, CHRISTOPHER M | SVP, Chief Scientific Officer | ストックオプション | 購入 | 60,000 | $0.00 |
| 2005-01-07 | SWIEDLER, STUART J | SVP, Clinical Affairs | ストックオプション | 購入 | 80,000 | $0.00 |
| 2005-01-07 | COOPER, JEFFREY H | Chief Financial Officer | ストックオプション | 購入 | 60,000 | $0.00 |
| 2005-01-07 | BAFFI, ROBERT | SVP, Technical Operations | ストックオプション | 購入 | 140,000 | $0.00 |
| 2004-11-30 | SAGER, ERICH | Director | ストックオプション | 購入 | 30,000 | $0.00 |
| 2004-11-30 | SAGER, ERICH | Director | ストックオプション | 購入 | 22,500 | $0.00 |
| 2004-11-30 | WILLIAMS, GWYNN | Director | ストックオプション | 購入 | 30,000 | $0.00 |
| 2004-10-31 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 購入 | 3,562 | $3.51 |
| 2004-10-31 | LANDAU, JEFFREY | SVP, Administration | 普通株式 | 購入 | 712 | $3.51 |
| 2004-10-31 | DRAPEAU, LOUIS | Chief Executive Officer | 普通株式 | 購入 | 3,687 | $3.51 |
| 2004-10-31 | KAKKIS, EMIL D | SVP, Business Operations | 普通株式 | 購入 | 1,924 | $3.51 |
| 2004-08-19 | DRAPEAU, LOUIS | Chief Executive Officer | ストックオプション | 購入 | 25,000 | $0.00 |
| 2004-08-19 | COOPER, JEFFREY H | Chief Financial Officer | ストックオプション | 購入 | 10,000 | $0.00 |
| 2004-07-28 | URQUHART, JOHN | Director | ストックオプション | 購入 | 30,000 | $0.00 |
| 2004-07-12 | HERON, ELAINE J | Director | ストックオプション | 購入 | 30,000 | $0.00 |
| 2004-06-14 | CRISTIANI, FRANZ L | Director | ストックオプション | 購入 | 30,000 | $0.00 |
| 2004-06-03 | STARR, CHRISTOPHER M | SVP, Chief Scientific Officer | 普通株式 | 売却 | 5,000 | $7.61 |
| 2004-06-03 | STARR, CHRISTOPHER M | SVP, Chief Scientific Officer | 普通株式 | 売却 | 5,000 | $7.66 |
| 2004-05-10 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 購入 | 1,200 | $6.11 |
| 2004-05-10 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 購入 | 8,000 | $6.12 |
| 2004-05-10 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 購入 | 6,800 | $6.12 |
| 2004-05-06 | KAKKIS, EMIL D | SVP, Business Operations | 普通株式 | 購入 | 5,000 | $6.48 |
| 2004-05-06 | PRICE, FREDRIC D | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $6.37 |
| 2004-05-06 | PRICE, FREDRIC D | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $6.27 |
| 2004-05-06 | KAKKIS, EMIL D | SVP, Business Operations | 普通株式 | 購入 | 10,000 | $6.50 |
| 2004-05-06 | PRICE, FREDRIC D | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $6.33 |
| 2004-05-03 | DRAPEAU, LOUIS | CFO, VP, Finance & Secretary | 普通株式 | 購入 | 2,192 | $5.70 |
| 2004-05-03 | BAFFI, ROBERT | SVP, Technical Operations | 普通株式 | 購入 | 2,423 | $5.10 |
| 2004-05-03 | LANDAU, JEFFREY | SVP, Administration | 普通株式 | 購入 | 491 | $5.10 |
| 2004-04-02 | STARR, CHRISTOPHER M | SVP, Chief Scientific Officer | ストックオプション | 売却 | 5,570 | $0.00 |
| 2004-04-02 | STARR, CHRISTOPHER M | SVP, Chief Scientific Officer | 普通株式 | 売却 | 5,570 | $8.00 |
| 2004-04-02 | STARR, CHRISTOPHER M | SVP, Chief Scientific Officer | 普通株式 | 購入 | 5,570 | $4.00 |
| 2004-04-01 | STARR, CHRISTOPHER M | SVP, Chief Scientific Officer | 普通株式 | 売却 | 5,000 | $7.56 |
売上・収益性
売上高（直近12ヶ月）
$322,125万ドル
一株あたり売上高（直近12ヶ月）
$16.80
売上総利益（直近12ヶ月）
$170,108万ドル
営業利益（EBITDA：減価償却前）
$72,288万ドル
利益率
10.8%
営業利益率（直近12ヶ月）
22.5%
配当・収入
配当金額（1株あたり）
$None
配当利回り
0%
支払日
None
権利落ち日
None
バリュエーション指標
株価収益率（PER）
30.29倍
実績PER
30.29倍
予想PER
11.14倍
株価収益成長率（PEG）
0.655
株価売上高倍率（直近12ヶ月）
3.256倍
株価純資産倍率 (PBR)
1.779倍
1株当たり純資産（BPS）
$31.65
企業価値倍率（EV）
EV/売上高倍率
3.065倍
EV/EBITDA倍率
17.23倍
投資リターン
総資産利益率（直近12ヶ月）
5.58%
自己資本利益率（直近12ヶ月）
5.94%
リターン分析
| 日数 | リターンレンジ | リターン中央値 | 累積リターン | 分散（バリアンス） | 標準偏差 | 最大下落率 | 最大下落期間 | SPYとの相関係数 | ||
|---|---|---|---|---|---|---|---|---|---|---|
| 15日間 | -3.1439% | 1.7432% | 0.3298% | -2.1597% | 0.0002932283127017884 | 0.017123910555179513 | -4.6678% | 2日 | -0.28619244168533153 | |
| 30日間 | -3.1439% | 3.1028% | -0.2163% | -5.7984% | 0.00032370908572484713 | 0.017991917233159092 | -5.7461% | 4日 | -0.07024268204322899 | |
| 90日間 | -3.2237% | 3.2462% | -0.0944% | -1.7614% | 0.0002793463993225362 | 0.016713659064445947 | -11.102% | 10日 | 0.040858494407225575 |
損益計算書
会計期末日
2025-12-31
報告通貨
USD
売上高・粗利益
売上原価
営業経費
営業利益・税引前指標
売上高
$3,221,253,000
粗利益
$2,484,425,000
売上コスト
$736,828,000
商品・サービス原価
$736,828,000
販売管理費
$1,153,017,000
研究開発
$921,930,000
運営コスト
$1,950,947,000
減価償却
$None
減価償却・償却費
$79,557,000
営業利益
$533,477,999
営業利益EBIT
$493,379,000
償却前営業利益EBITA
$572,936,000
税引前利益
$482,480,000
利息・投資・その他営業外項目
税金関連
当期純・包括利益
純投資収益
$None
純金利収入
$64,005,000
利息収入
$74,904,000
金利コスト
$10,899,000
利息・債務コスト
$None
非利息収益
$None
営業外収益（その他）
$None
法人税等
$133,579,000
継続事業純利益
$348,901,000
純利益
$348,901,000
税引後包括利益
$None
貸借対照表
会計期末日
2025-12-31
報告通貨
USD
総資産
$7,594,022,000
現金及び現金同等物
$1,311,679,000
現金及び短期投資
$1,311,679,000
短期投資
$248,930,000
在庫資産
$1,298,883,000
流動売掛金（純額）
$908,214,000
その他流動資産
$185,784,000
流動資産合計
$3,953,490,000
有形固定資産
$None
減価償却累計額（PPE）
$None
無形資産
$213,837,000
無形資産（のれん除く）
$213,837,000
のれん（無形資産）
$196,199,000
投資
$None
長期投資
$492,242,000
その他固定資産
$None
固定資産合計
$3,640,532,000
総負債
$1,507,023,000
買掛金（短期）
$312,768,000
前受金
$None
流動債務
$None
短期借入金
$8,685,000
固定長期負債
$None
その他流動負債
$437,578,000
流動負債合計
$759,031,000
リース債務
$8,685,000
長期債務
$597,176,000
長期債務（流動外）
$None
短期・長期借入金合計
$642,873,000
その他固定負債
$150,816,000
固定負債合計
$747,992,000
純資産
$6,086,999,000
自己株式（金庫株）
$None
利益剰余金
$154,206,000
普通株式
$192,000
発行済株式数（普通株）
$197,394,000
キャッシュフロー計算書
会計期末日
2025-12-31
報告通貨
USD
損益計算・収益性
営業活動
投資活動
損益
$None
純利益
$348,901,000
営業キャッシュフロー
$827,994,000
営業活動による支払い
$None
営業活動によるキャッシュフロー
$None
営業活動に関連する負債の増減額
$None
営業活動に関連する資産の増減額
$None
売掛金の増減額
$None
在庫資産の増減額
$119,208,000
減価償却・減耗費・償却費
$79,557,000
投資活動によるキャッシュフロー
-$414,242,000
設備投資
$103,038,000
財務活動
資金・為替照合
財務活動によるキャッシュフロー
-$42,394,000
短期融資回収金
$None
自社株買い支出（普通株）
$None
自社株買い支出（優先株）
$None
自社株買い支出
$None
配当支払い（普通株）
$None
配当支払い（優先株）
$None
配当支払い
$None
資金調達（普通株）
$None
資金調達（優先株）
$None
資金調達（長期債・資本証券）
$None
自社株売却による収益
$None
自社株再取得による収益
$None
現金及び現金同等物の増減額
$None
為替レートの変動による増減額
$None
発行済株式数
広告パネル
スポンサー紹介
本物のネイティブ講師による
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