INCY
インサイト・コーポレーション
Incyte Corporation
株価・概要
$95.32
-1.78 (-1.8332%)
06:00AM 2026/04/17 (JST)
NASDAQ | USD
52週間レンジ
56.13
112.29
昨夜レンジ
94.56
97.53
前日終値
$97.10
出来高（数量）
1,616,846
ベータ値
0.857
50日移動平均値
$97.45
200日移動平均値
$91.40
1株あたりの利益（EPS）
6.41
予想PER（株価収益率）
13.02
配当金
$None
配当利回り
0%
インサイダー保有率
1.871%
機関投資家保有率
105.331%
INCY - 会社概要
インサイト・コーポレーション（INCY）は、デラウェア州ウィルミントンに本社を置く、がんやその他の重篤な疾患のための革新的な治療法の開発に取り組む著名なバイオ医薬品企業です。1991年の設立以来、インサイトは骨髄線維症および真性多血症の治療薬である主力製品ジャカフィによって大きな商業的成功を収めるとともに、さまざまな悪性腫瘍を標的とした有望な新薬候補のパイプラインを推進しています。精密医療への取り組みと戦略的な提携により、同社は医療分野における重要な未充足医療ニーズへの対応の最前線に位置しています。科学的イノベーションと患者の治療成果の向上を重視することで、インサイトはバイオ医薬品業界における影響力のある役割を今後も維持していく態勢を整えています。
本社住所
1801 AUGUSTINE CUT-OFF, WILMINGTON, DE, UNITED STATES, 19803
企業サイト
https://www.incyte.com
会計年度終了
December
最新四半期
2025-12-31
利益・成長性
1株あたりの利益（EPS）
$6.41
希薄化後1株当たり利益EPS（直近12ヶ月）
$6.41
四半期利益成長率（前年比）
43.6%
四半期売上成長率（前年比）
27.8%
アナリスト予想・評価
目標株価
$107.27
強気
2
買い
9
ホールド
12
売り
1
弱気
1
EPS（1株当たり純利益）
| 7日前 | 30日前 | 60日前 | 90日前 | 予想レンジ | |||
|---|---|---|---|---|---|---|---|
配当履歴
| 権利落ち日 | 配当宣言日 | 権利確定日 | 配当金支払日 | 配当金額 |
|---|
株式分割
| 効力発生日 | 分割比率 |
|---|---|
| 2000-09-01 | 2.0000 |
インサイダーの売却・購入履歴
| 自社株取引日 | 役員・従業員名 | 役員・従業員の役職 | 株式の種類 | 売却／購入 | 株数 | 株価 |
|---|---|---|---|---|---|---|
| 2026-03-31 | CLANCY, PAUL J | Director | 普通株式 | 購入 | 265 | $94.12 |
| 2026-03-31 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 421 | $0.00 |
| 2026-03-31 | HARRIGAN, EDMUND | Director | 普通株式 | 購入 | 269 | $94.12 |
| 2026-03-25 | TROTTA, MATTEO | EVP, GM, Dermatology US | 普通株式 | 売却 | 537 | $92.23 |
| 2026-03-17 | CAGNONI, PABLO J | President, R&D | 普通株式 | 購入 | 11,501 | $64.25 |
| 2026-03-17 | CAGNONI, PABLO J | President, R&D | ストックオプション | 売却 | 11,501 | $0.00 |
| 2026-03-17 | CAGNONI, PABLO J | President, R&D | ストックオプション | 売却 | 7,166 | $0.00 |
| 2026-03-17 | CAGNONI, PABLO J | President, R&D | 普通株式 | 売却 | 18,667 | $94.24 |
| 2026-03-17 | CAGNONI, PABLO J | President, R&D | 普通株式 | 購入 | 7,166 | $61.18 |
| 2026-02-19 | CAGNONI, PABLO J | President, R&D | 普通株式 | 購入 | 5,575 | $61.18 |
| 2026-02-19 | CAGNONI, PABLO J | President, R&D | 普通株式 | 購入 | 13,093 | $61.76 |
| 2026-02-19 | CAGNONI, PABLO J | President, R&D | 普通株式 | 売却 | 18,668 | $100.91 |
| 2026-02-19 | CAGNONI, PABLO J | President, R&D | ストックオプション | 売却 | 13,093 | $0.00 |
| 2026-02-19 | CAGNONI, PABLO J | President, R&D | ストックオプション | 売却 | 5,575 | $0.00 |
| 2026-02-02 | HEESON, LEE | EVP, Head of Incyte Intl | 普通株式 | 売却 | 111 | $102.67 |
| 2026-02-02 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 売却 | 185 | $102.67 |
| 2026-01-20 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 売却 | 429 | $102.62 |
| 2026-01-16 | ISSA, MOHAMED KHAIRIE | EVP, Head of US Oncology | ストックオプション | 購入 | 14,237 | $0.00 |
| 2026-01-16 | HEESON, LEE | EVP, Head of Incyte Intl | 普通株式 | 購入 | 8,911 | $0.00 |
| 2026-01-16 | TROTTA, MATTEO | EVP, GM, Dermatology US | ストックオプション | 購入 | 8,542 | $0.00 |
| 2026-01-16 | CAGNONI, PABLO J | President, R&D | ストックオプション | 購入 | 28,475 | $0.00 |
| 2026-01-16 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 購入 | 19,932 | $0.00 |
| 2026-01-16 | TRAY, THOMAS | Principal Accounting Officer | ストックオプション | 購入 | 2,425 | $0.00 |
| 2026-01-16 | MAYES, PATRICK A | EVP & Chief Scientific Officer | ストックオプション | 購入 | 4,218 | $0.00 |
| 2026-01-16 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 購入 | 7,426 | $0.00 |
| 2026-01-07 | ISSA, MOHAMED KHAIRIE | EVP, Head of US Oncology | 普通株式 | 売却 | 10,856 | $109.07 |
| 2026-01-06 | ISSA, MOHAMED KHAIRIE | EVP, Head of US Oncology | 普通株式 | 売却 | 8,264 | $106.66 |
| 2026-01-05 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 15,634 | $101.70 |
| 2025-12-31 | HARRIGAN, EDMUND | Director | 普通株式 | 購入 | 245 | $98.77 |
| 2025-12-31 | CLANCY, PAUL J | Director | 普通株式 | 購入 | 241 | $98.77 |
| 2025-12-31 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 328 | $0.00 |
| 2025-12-31 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 売却 | 254 | $98.77 |
| 2025-12-31 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 13,292 | $98.77 |
| 2025-12-19 | TRAY, THOMAS | Principal Accounting Officer | 普通株式 | 購入 | 1,730 | $95.76 |
| 2025-12-19 | TRAY, THOMAS | Principal Accounting Officer | 普通株式 | 売却 | 2,774 | $100.00 |
| 2025-12-19 | TRAY, THOMAS | Principal Accounting Officer | 普通株式 | 購入 | 1,044 | $95.76 |
| 2025-12-19 | TRAY, THOMAS | Principal Accounting Officer | ストックオプション | 売却 | 1,044 | $0.00 |
| 2025-12-19 | TRAY, THOMAS | Principal Accounting Officer | ストックオプション | 売却 | 1,730 | $0.00 |
| 2025-12-18 | TRAY, THOMAS | Principal Accounting Officer | 普通株式 | 売却 | 600 | $98.25 |
| 2025-12-17 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 売却 | 4,323 | $97.26 |
| 2025-12-16 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 売却 | 53,175 | $97.29 |
| 2025-12-16 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 売却 | 833 | $97.42 |
| 2025-12-11 | MAYES, PATRICK A | EVP & Chief Scientific Officer | 普通株式 | 売却 | 255 | $94.94 |
| 2025-12-10 | MAYES, PATRICK A | EVP & Chief Scientific Officer | 普通株式 | 売却 | 5,553 | $95.58 |
| 2025-12-08 | HOPPENOT, HERVE | Director | 普通株式 | 売却 | 2,843 | $96.70 |
| 2025-12-02 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 20,105 | $102.51 |
| 2025-12-01 | HOFFMAN, RICHARD A. | EVP & General Counsel | 普通株式 | 購入 | 9,466 | $0.00 |
| 2025-12-01 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 売却 | 326 | $102.04 |
| 2025-12-01 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 17,093 | $102.04 |
| 2025-12-01 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 2,559 | $102.96 |
| 2025-12-01 | HOFFMAN, RICHARD A. | EVP & General Counsel | 普通株式 | 購入 | 23,665 | $0.00 |
| 2025-12-01 | HOFFMAN, RICHARD A. | EVP & General Counsel | ストックオプション | 購入 | 43,301 | $0.00 |
| 2025-11-24 | TRAY, THOMAS | Principal Accounting Officer | 普通株式 | 売却 | 600 | $103.00 |
| 2025-11-21 | TRAY, THOMAS | Principal Accounting Officer | 普通株式 | 売却 | 169 | $102.00 |
| 2025-11-17 | DENTON, SHEILA A. | EVP & General Counsel | 普通株式 | 購入 | 278 | $64.25 |
| 2025-11-17 | DENTON, SHEILA A. | EVP & General Counsel | ストックオプション | 売却 | 278 | $0.00 |
| 2025-11-17 | DENTON, SHEILA A. | EVP & General Counsel | 普通株式 | 売却 | 278 | $104.36 |
| 2025-11-10 | HOPPENOT, HERVE | Director | 普通株式 | 売却 | 187,500 | $105.46 |
| 2025-11-05 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 1,194 | $83.83 |
| 2025-11-05 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 2,995 | $95.76 |
| 2025-11-05 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 売却 | 1,044 | $0.00 |
| 2025-11-05 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 売却 | 2,995 | $0.00 |
| 2025-11-05 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 売却 | 1,194 | $0.00 |
| 2025-11-05 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 5,233 | $102.20 |
| 2025-11-05 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 1,044 | $95.76 |
| 2025-11-04 | DENTON, SHEILA A. | EVP & General Counsel | 普通株式 | 購入 | 598 | $58.06 |
| 2025-11-04 | DENTON, SHEILA A. | EVP & General Counsel | ストックオプション | 売却 | 598 | $0.00 |
| 2025-11-04 | DENTON, SHEILA A. | EVP & General Counsel | 普通株式 | 売却 | 598 | $101.36 |
| 2025-11-03 | HEESON, LEE | EVP, Head of Incyte Intl | 普通株式 | 売却 | 3,074 | $94.02 |
| 2025-10-15 | DENTON, SHEILA A. | EVP & General Counsel | 普通株式 | 売却 | 277 | $85.13 |
| 2025-10-15 | DENTON, SHEILA A. | EVP & General Counsel | 普通株式 | 購入 | 277 | $64.25 |
| 2025-10-15 | DENTON, SHEILA A. | EVP & General Counsel | ストックオプション | 売却 | 277 | $0.00 |
| 2025-10-03 | DENTON, SHEILA A. | EVP & General Counsel | 普通株式 | 売却 | 3,501 | $85.54 |
| 2025-10-02 | DENTON, SHEILA A. | EVP & General Counsel | 普通株式 | 購入 | 599 | $58.06 |
| 2025-10-02 | DENTON, SHEILA A. | EVP & General Counsel | 普通株式 | 売却 | 3,130 | $86.28 |
| 2025-10-02 | DENTON, SHEILA A. | EVP & General Counsel | ストックオプション | 売却 | 599 | $0.00 |
| 2025-10-02 | DENTON, SHEILA A. | EVP & General Counsel | 普通株式 | 売却 | 599 | $87.65 |
| 2025-10-01 | MAYES, PATRICK A | EVP & Chief Scientific Officer | 普通株式 | 売却 | 1,569 | $86.70 |
| 2025-10-01 | HEESON, LEE | EVP, Head of Incyte Intl | 普通株式 | 売却 | 463 | $86.70 |
| 2025-09-30 | CLANCY, PAUL J | Director | 普通株式 | 購入 | 285 | $84.81 |
| 2025-09-30 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 388 | $0.00 |
| 2025-09-30 | HARRIGAN, EDMUND | Director | 普通株式 | 購入 | 289 | $84.81 |
| 2025-09-22 | GARDNER, DAVID H | EVP, Chief Strategy Officer | 普通株式 | 購入 | 23,573 | $0.00 |
| 2025-09-22 | GARDNER, DAVID H | EVP, Chief Strategy Officer | 普通株式 | 購入 | 9,429 | $0.00 |
| 2025-09-22 | GARDNER, DAVID H | EVP, Chief Strategy Officer | ストックオプション | 購入 | 42,899 | $0.00 |
| 2025-09-16 | DENTON, SHEILA A. | EVP & General Counsel | 普通株式 | 売却 | 278 | $83.15 |
| 2025-09-16 | DENTON, SHEILA A. | EVP & General Counsel | 普通株式 | 購入 | 278 | $64.25 |
| 2025-09-16 | DENTON, SHEILA A. | EVP & General Counsel | ストックオプション | 売却 | 278 | $0.00 |
| 2025-09-02 | DENTON, SHEILA A. | EVP & General Counsel | 普通株式 | 購入 | 598 | $58.06 |
| 2025-09-02 | DENTON, SHEILA A. | EVP & General Counsel | ストックオプション | 売却 | 598 | $0.00 |
| 2025-09-02 | DENTON, SHEILA A. | EVP & General Counsel | 普通株式 | 売却 | 598 | $84.97 |
| 2025-08-25 | BASI, RAMITPAL K | EVP, Human Resources | 普通株式 | 購入 | 16,265 | $0.00 |
| 2025-08-25 | BASI, RAMITPAL K | EVP, Human Resources | 普通株式 | 購入 | 6,506 | $0.00 |
| 2025-08-25 | BASI, RAMITPAL K | EVP, Human Resources | ストックオプション | 購入 | 29,230 | $0.00 |
| 2025-08-15 | DENTON, SHEILA A. | EVP & General Counsel | 普通株式 | 購入 | 277 | $64.25 |
| 2025-08-15 | DENTON, SHEILA A. | EVP & General Counsel | ストックオプション | 売却 | 277 | $0.00 |
| 2025-08-15 | DENTON, SHEILA A. | EVP & General Counsel | 普通株式 | 売却 | 277 | $86.81 |
| 2025-08-04 | DENTON, SHEILA A. | EVP & General Counsel | 普通株式 | 購入 | 598 | $58.06 |
| 2025-08-04 | DENTON, SHEILA A. | EVP & General Counsel | ストックオプション | 売却 | 598 | $0.00 |
| 2025-08-04 | DENTON, SHEILA A. | EVP & General Counsel | 普通株式 | 売却 | 598 | $75.77 |
| 2025-07-21 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 3,706 | $67.94 |
| 2025-07-16 | IYENGAR, VIJAY K | EVP, GMAPPS | 普通株式 | 売却 | 983 | $68.36 |
| 2025-07-16 | DENTON, SHEILA A. | EVP & General Counsel | 普通株式 | 売却 | 785 | $68.36 |
| 2025-07-16 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 1,340 | $68.36 |
| 2025-07-15 | CAGNONI, PABLO J | President, R&D | ストックオプション | 購入 | 39,471 | $0.00 |
| 2025-07-15 | DENTON, SHEILA A. | EVP & General Counsel | 普通株式 | 売却 | 3,330 | $69.86 |
| 2025-07-15 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | ストックオプション | 購入 | 24,998 | $0.00 |
| 2025-07-15 | HEESON, LEE | EVP, Head of Incyte Intl | 普通株式 | 購入 | 6,577 | $0.00 |
| 2025-07-15 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | 普通株式 | 購入 | 27,769 | $0.00 |
| 2025-07-15 | HOPPENOT, HERVE | Director, Special Advisor to the CEO | 普通株式 | 売却 | 4,713 | $68.25 |
| 2025-07-15 | DENTON, SHEILA A. | EVP & General Counsel | ストックオプション | 売却 | 3,330 | $0.00 |
| 2025-07-15 | DENTON, SHEILA A. | EVP & General Counsel | 普通株式 | 購入 | 20,461 | $0.00 |
| 2025-07-15 | DENTON, SHEILA A. | EVP & General Counsel | ストックオプション | 購入 | 18,419 | $0.00 |
| 2025-07-15 | ISSA, MOHAMED KHAIRIE | EVP, Head of US Oncology | 普通株式 | 購入 | 8,769 | $0.00 |
| 2025-07-15 | ISSA, MOHAMED KHAIRIE | EVP, Head of US Oncology | 普通株式 | 購入 | 21,923 | $0.00 |
| 2025-07-15 | ISSA, MOHAMED KHAIRIE | EVP, Head of US Oncology | ストックオプション | 購入 | 19,735 | $0.00 |
| 2025-07-15 | TROTTA, MATTEO | EVP, GM, Dermatology US | 普通株式 | 売却 | 182 | $68.25 |
| 2025-07-15 | TROTTA, MATTEO | EVP, GM, Dermatology US | 普通株式 | 購入 | 5,261 | $0.00 |
| 2025-07-15 | TROTTA, MATTEO | EVP, GM, Dermatology US | 普通株式 | 購入 | 13,154 | $0.00 |
| 2025-07-15 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 1,596 | $68.25 |
| 2025-07-15 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 12,277 | $0.00 |
| 2025-07-15 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 購入 | 27,629 | $0.00 |
| 2025-07-15 | TRAY, THOMAS | Principal Accounting Officer | 普通株式 | 売却 | 583 | $68.25 |
| 2025-07-15 | DENTON, SHEILA A. | EVP & General Counsel | 普通株式 | 売却 | 703 | $68.25 |
| 2025-07-15 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 16,077 | $0.00 |
| 2025-07-15 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 563 | $68.25 |
| 2025-07-15 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 30,692 | $0.00 |
| 2025-07-15 | TROTTA, MATTEO | EVP, GM, Dermatology US | ストックオプション | 購入 | 11,841 | $0.00 |
| 2025-07-15 | TRAY, THOMAS | Principal Accounting Officer | 普通株式 | 購入 | 4,482 | $0.00 |
| 2025-07-15 | TRAY, THOMAS | Principal Accounting Officer | ストックオプション | 購入 | 3,362 | $0.00 |
| 2025-07-15 | DENTON, SHEILA A. | EVP & General Counsel | 普通株式 | 購入 | 3,330 | $64.25 |
| 2025-07-15 | IYENGAR, VIJAY K | EVP, GMAPPS | 普通株式 | 売却 | 1,177 | $69.86 |
| 2025-07-15 | IYENGAR, VIJAY K | EVP, GMAPPS | 普通株式 | 売却 | 836 | $68.25 |
| 2025-07-15 | IYENGAR, VIJAY K | EVP, GMAPPS | 普通株式 | 購入 | 6,430 | $0.00 |
| 2025-07-15 | IYENGAR, VIJAY K | EVP, GMAPPS | 普通株式 | 購入 | 16,077 | $0.00 |
| 2025-07-15 | IYENGAR, VIJAY K | EVP, GMAPPS | ストックオプション | 購入 | 14,472 | $0.00 |
| 2025-07-15 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 1,141 | $68.25 |
| 2025-07-15 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 14,472 | $0.00 |
| 2025-07-15 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | 普通株式 | 売却 | 1,445 | $68.25 |
| 2025-07-15 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | 普通株式 | 購入 | 11,107 | $0.00 |
| 2025-07-15 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 6,430 | $0.00 |
| 2025-07-15 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 購入 | 10,961 | $0.00 |
| 2025-07-15 | CAGNONI, PABLO J | President, R&D | 普通株式 | 売却 | 2,628 | $68.25 |
| 2025-07-15 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 1,192 | $69.86 |
| 2025-07-15 | CAGNONI, PABLO J | President, R&D | 普通株式 | 購入 | 17,538 | $0.00 |
| 2025-07-15 | CAGNONI, PABLO J | President, R&D | 普通株式 | 購入 | 43,846 | $0.00 |
| 2025-07-15 | DENTON, SHEILA A. | EVP & General Counsel | 普通株式 | 購入 | 8,184 | $0.00 |
| 2025-07-14 | TRAY, THOMAS | Principal Accounting Officer | 普通株式 | 売却 | 692 | $69.98 |
| 2025-07-14 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | 普通株式 | 売却 | 1,407 | $69.98 |
| 2025-07-14 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 14,952 | $68.47 |
| 2025-07-14 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 1,555 | $69.98 |
| 2025-07-14 | IYENGAR, VIJAY K | EVP, GMAPPS | 普通株式 | 売却 | 595 | $69.98 |
| 2025-07-14 | CAGNONI, PABLO J | President, R&D | 普通株式 | 売却 | 1,280 | $69.98 |
| 2025-07-14 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 444 | $69.98 |
| 2025-07-14 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 922 | $69.98 |
| 2025-07-14 | HOPPENOT, HERVE | Director, Special Advisor to the CEO | 普通株式 | 売却 | 4,961 | $69.98 |
| 2025-07-03 | IYENGAR, VIJAY K | EVP, GMAPPS | 普通株式 | 売却 | 5,935 | $68.15 |
| 2025-07-03 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 10,903 | $68.15 |
| 2025-07-03 | IYENGAR, VIJAY K | EVP, GMAPPS | 普通株式 | 売却 | 2,682 | $68.16 |
| 2025-07-02 | DENTON, SHEILA A. | EVP & General Counsel | 普通株式 | 売却 | 599 | $68.61 |
| 2025-07-02 | DENTON, SHEILA A. | EVP & General Counsel | 普通株式 | 購入 | 599 | $58.06 |
| 2025-07-02 | TRAY, THOMAS | Principal Accounting Officer | 普通株式 | 売却 | 897 | $68.17 |
| 2025-07-02 | MEURY, WILLIAM | Director, Chief Executive Officer, President | 普通株式 | 購入 | 108,303 | $0.00 |
| 2025-07-02 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 6,285 | $68.17 |
| 2025-07-02 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 12,714 | $68.17 |
| 2025-07-02 | HOPPENOT, HERVE | Director, Special Advisor to the CEO | 普通株式 | 売却 | 42,769 | $68.17 |
| 2025-07-02 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | 普通株式 | 売却 | 11,589 | $68.17 |
| 2025-07-02 | MEURY, WILLIAM | Director, Chief Executive Officer, President | 普通株式 | 購入 | 36,101 | $0.00 |
| 2025-07-02 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 9,055 | $68.17 |
| 2025-07-02 | MEURY, WILLIAM | Director, Chief Executive Officer, President | 普通株式 | 購入 | 125,000 | $0.00 |
| 2025-07-02 | IYENGAR, VIJAY K | EVP, GMAPPS | 普通株式 | 売却 | 6,809 | $68.17 |
| 2025-07-02 | DENTON, SHEILA A. | EVP & General Counsel | ストックオプション | 売却 | 599 | $0.00 |
| 2025-06-30 | CLANCY, PAUL J | Director | 普通株式 | 購入 | 361 | $68.10 |
| 2025-06-30 | HARRIGAN, EDMUND | Director | 普通株式 | 購入 | 367 | $68.10 |
| 2025-06-30 | ISSA, MOHAMED KHAIRIE | EVP, Head of US Oncology | 普通株式 | 購入 | 27,812 | $0.00 |
| 2025-06-30 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 492 | $0.00 |
| 2025-06-26 | MEURY, WILLIAM | Director, Chief Executive Officer, President | ストックオプション | 購入 | 110,630 | $0.00 |
| 2025-06-26 | HOPPENOT, HERVE | Director, Special Advisor to the CEO | 普通株式 | 購入 | 6,016 | $0.00 |
| 2025-06-26 | HOPPENOT, HERVE | Director, Special Advisor to the CEO | ストックオプション | 購入 | 18,438 | $0.00 |
| 2025-06-26 | HOPPENOT, HERVE | Director, Special Advisor to the CEO | 普通株式 | 購入 | 18,050 | $0.00 |
| 2025-06-10 | SCHAFFERT, SUSANNE | Director | 普通株式 | 売却 | 849 | $70.07 |
| 2025-06-10 | SCHAFFERT, SUSANNE | Director | 普通株式 | 購入 | 2,518 | $0.00 |
| 2025-06-10 | SCHAFFERT, SUSANNE | Director | ストックオプション | 購入 | 9,216 | $0.00 |
| 2025-06-10 | HARRIGAN, EDMUND | Director | 普通株式 | 購入 | 2,518 | $0.00 |
| 2025-06-10 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 2,518 | $0.00 |
| 2025-06-10 | HIGH, KATHERINE A | Director | ストックオプション | 購入 | 9,216 | $0.00 |
| 2025-06-10 | HIGH, KATHERINE A | Director | 普通株式 | 購入 | 2,518 | $0.00 |
| 2025-06-10 | BIENAIME, JEAN JACQUES | Director | ストックオプション | 購入 | 9,216 | $0.00 |
| 2025-06-10 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 2,518 | $0.00 |
| 2025-06-10 | FOUSE, JACQUALYN A | Director | ストックオプション | 購入 | 9,216 | $0.00 |
| 2025-06-10 | FOUSE, JACQUALYN A | Director | 普通株式 | 購入 | 2,518 | $0.00 |
| 2025-06-10 | BRAWLEY, OTIS W | Director | ストックオプション | 購入 | 9,216 | $0.00 |
| 2025-06-10 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | ストックオプション | 購入 | 9,216 | $0.00 |
| 2025-06-10 | BRAWLEY, OTIS W | Director | 普通株式 | 購入 | 2,518 | $0.00 |
| 2025-06-10 | HARRIGAN, EDMUND | Director | ストックオプション | 購入 | 9,216 | $0.00 |
| 2025-06-10 | CLANCY, PAUL J | Director | 普通株式 | 購入 | 2,518 | $0.00 |
| 2025-06-10 | CLANCY, PAUL J | Director | ストックオプション | 購入 | 9,216 | $0.00 |
| 2025-06-03 | DENTON, SHEILA A. | EVP & General Counsel | 普通株式 | 売却 | 1,795 | $68.00 |
| 2025-06-03 | DENTON, SHEILA A. | EVP & General Counsel | ストックオプション | 売却 | 1,795 | $0.00 |
| 2025-06-03 | DENTON, SHEILA A. | EVP & General Counsel | 普通株式 | 購入 | 1,795 | $58.06 |
| 2025-06-02 | TRAY, THOMAS | Principal Accounting Officer | 普通株式 | 売却 | 651 | $64.88 |
| 2025-05-30 | TRAY, THOMAS | Principal Accounting Officer | 普通株式 | 売却 | 963 | $65.71 |
| 2025-04-01 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | 普通株式 | 購入 | 18,970 | $0.00 |
| 2025-04-01 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 購入 | 11,159 | $0.00 |
| 2025-04-01 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 購入 | 14,976 | $0.00 |
| 2025-04-01 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | 普通株式 | 購入 | 18,598 | $0.00 |
| 2025-04-01 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 37,198 | $0.00 |
| 2025-04-01 | IYENGAR, VIJAY K | EVP, GMAPPS | 普通株式 | 購入 | 11,159 | $0.00 |
| 2025-04-01 | IYENGAR, VIJAY K | EVP, GMAPPS | 普通株式 | 購入 | 10,982 | $0.00 |
| 2025-04-01 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 購入 | 4,649 | $0.00 |
| 2025-04-01 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 購入 | 66,899 | $0.00 |
| 2025-04-01 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 10,982 | $0.00 |
| 2025-04-01 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 11,159 | $0.00 |
| 2025-04-01 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 20,967 | $0.00 |
| 2025-03-31 | CLANCY, PAUL J | Director | 普通株式 | 購入 | 358 | $60.55 |
| 2025-03-31 | HARRIGAN, EDMUND | Director | 普通株式 | 購入 | 363 | $60.55 |
| 2025-03-31 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 487 | $0.00 |
| 2025-03-25 | TROTTA, MATTEO | EVP, GM, Dermatology US | 普通株式 | 売却 | 537 | $62.08 |
| 2025-03-14 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 19,147 | $67.68 |
| 2025-03-14 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 461 | $67.85 |
| 2025-03-14 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 199 | $67.88 |
| 2025-03-04 | DENTON, SHEILA A. | EVP & General Counsel | 普通株式 | 売却 | 599 | $69.99 |
| 2025-03-04 | DENTON, SHEILA A. | EVP & General Counsel | 普通株式 | 購入 | 599 | $58.06 |
| 2025-03-04 | DENTON, SHEILA A. | EVP & General Counsel | ストックオプション | 売却 | 599 | $0.00 |
| 2025-02-26 | DENTON, SHEILA A. | EVP & General Counsel | ストックオプション | 売却 | 9,574 | $0.00 |
| 2025-02-26 | DENTON, SHEILA A. | EVP & General Counsel | 普通株式 | 売却 | 9,574 | $74.07 |
| 2025-02-26 | DENTON, SHEILA A. | EVP & General Counsel | 普通株式 | 売却 | 4,495 | $74.08 |
| 2025-02-26 | DENTON, SHEILA A. | EVP & General Counsel | 普通株式 | 購入 | 9,574 | $58.06 |
| 2025-01-31 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 購入 | 10,552 | $0.00 |
| 2025-01-31 | HEESON, LEE | EVP, Head of Incyte Intl | 普通株式 | 購入 | 6,331 | $0.00 |
| 2025-01-21 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 売却 | 429 | $73.47 |
| 2025-01-21 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 12,352 | $72.69 |
| 2025-01-17 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 購入 | 20,144 | $0.00 |
| 2025-01-17 | HOPPENOT, HERVE | Director, Chairman / CEO, President | ストックオプション | 購入 | 55,510 | $0.00 |
| 2025-01-17 | TRAY, THOMAS | Principal Accounting Officer | ストックオプション | 購入 | 3,432 | $0.00 |
| 2025-01-17 | CAGNONI, PABLO J | President, R&D | ストックオプション | 購入 | 40,289 | $0.00 |
| 2025-01-17 | DENTON, SHEILA A. | EVP & General Counsel | ストックオプション | 購入 | 12,086 | $0.00 |
| 2025-01-17 | TROTTA, MATTEO | EVP, GM, Dermatology US | ストックオプション | 購入 | 5,371 | $0.00 |
| 2025-01-17 | IYENGAR, VIJAY K | EVP, GMAPPS | ストックオプション | 購入 | 14,772 | $0.00 |
| 2025-01-17 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 購入 | 28,202 | $0.00 |
| 2025-01-17 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 14,772 | $0.00 |
| 2025-01-17 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | ストックオプション | 購入 | 25,516 | $0.00 |
| 2025-01-15 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | 普通株式 | 売却 | 3,672 | $72.46 |
| 2025-01-15 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 3,158 | $72.46 |
| 2025-01-15 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 売却 | 908 | $72.46 |
| 2025-01-15 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 10,692 | $72.46 |
| 2025-01-06 | ISSA, MOHAMED KHAIRIE | EVP, Head of US Oncology | 普通株式 | 購入 | 48,671 | $0.00 |
| 2024-12-31 | HARRIGAN, EDMUND | Director | 普通株式 | 購入 | 339 | $69.07 |
| 2024-12-31 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 446 | $0.00 |
| 2024-12-31 | CLANCY, PAUL J | Director | 普通株式 | 購入 | 331 | $69.07 |
| 2024-12-16 | TRAY, THOMAS | Principal Accounting Officer | 普通株式 | 売却 | 650 | $69.31 |
| 2024-12-13 | TRAY, THOMAS | Principal Accounting Officer | 普通株式 | 売却 | 650 | $70.64 |
| 2024-12-09 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 1,510 | $72.11 |
| 2024-12-09 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 873 | $72.11 |
| 2024-11-29 | IYENGAR, VIJAY K | EVP, GMAPPS | 普通株式 | 売却 | 360 | $75.60 |
| 2024-11-29 | IYENGAR, VIJAY K | EVP, GMAPPS | 普通株式 | 売却 | 5,683 | $75.37 |
| 2024-11-06 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 購入 | 2,256 | $68.62 |
| 2024-11-06 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 2,256 | $78.21 |
| 2024-11-06 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 1,424 | $82.00 |
| 2024-11-06 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 購入 | 1,424 | $72.27 |
| 2024-11-06 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 売却 | 1,424 | $0.00 |
| 2024-11-06 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 売却 | 2,256 | $0.00 |
| 2024-10-02 | DENTON, SHEILA A. | EVP & General Counsel | 普通株式 | 売却 | 2,136 | $67.63 |
| 2024-10-01 | HEESON, LEE | EVP, Head of Incyte Intl | 普通株式 | 購入 | 26,447 | $0.00 |
| 2024-09-30 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 496 | $0.00 |
| 2024-09-30 | HARRIGAN, EDMUND | Director | 普通株式 | 購入 | 378 | $66.10 |
| 2024-09-30 | CLANCY, PAUL J | Director | 普通株式 | 購入 | 368 | $66.10 |
| 2024-09-13 | TRAY, THOMAS | Principal Accounting Officer | 普通株式 | 売却 | 382 | $63.37 |
| 2024-09-12 | DICKINSON, JONATHAN ELLIOTT | EVP, General Manager, Europe | 普通株式 | 売却 | 7,333 | $62.37 |
| 2024-09-12 | DICKINSON, JONATHAN ELLIOTT | EVP, General Manager, Europe | 普通株式 | 売却 | 1,117 | $62.30 |
| 2024-09-12 | TRAY, THOMAS | Principal Accounting Officer | 普通株式 | 売却 | 572 | $62.94 |
| 2024-08-12 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 11,608 | $60.63 |
| 2024-07-25 | IYENGAR, VIJAY K | EVP, GMAPPS | 普通株式 | 売却 | 15,571 | $70.00 |
| 2024-07-16 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 1,306 | $64.19 |
| 2024-07-15 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 1,555 | $64.25 |
| 2024-07-15 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 13,895 | $0.00 |
| 2024-07-15 | CAGNONI, PABLO J | President, R&D | 普通株式 | 購入 | 19,851 | $0.00 |
| 2024-07-15 | CAGNONI, PABLO J | President, R&D | 普通株式 | 売却 | 749 | $64.25 |
| 2024-07-15 | CAGNONI, PABLO J | President, R&D | ストックオプション | 購入 | 44,411 | $0.00 |
| 2024-07-15 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 購入 | 41,025 | $0.00 |
| 2024-07-15 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 売却 | 4,961 | $64.25 |
| 2024-07-15 | TROTTA, MATTEO | EVP, GM, Dermatology US | 普通株式 | 購入 | 2,646 | $0.00 |
| 2024-07-15 | HOPPENOT, HERVE | Director, Chairman / CEO, President | ストックオプション | 購入 | 61,189 | $0.00 |
| 2024-07-15 | IYENGAR, VIJAY K | EVP, GMAPPS | 普通株式 | 購入 | 7,278 | $0.00 |
| 2024-07-15 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | 普通株式 | 購入 | 12,572 | $0.00 |
| 2024-07-15 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | 普通株式 | 売却 | 948 | $64.25 |
| 2024-07-15 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | ストックオプション | 購入 | 28,127 | $0.00 |
| 2024-07-15 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 購入 | 9,925 | $0.00 |
| 2024-07-15 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 1,111 | $64.25 |
| 2024-07-15 | IYENGAR, VIJAY K | EVP, GMAPPS | ストックオプション | 購入 | 16,284 | $0.00 |
| 2024-07-15 | IYENGAR, VIJAY K | EVP, GMAPPS | 普通株式 | 売却 | 549 | $64.25 |
| 2024-07-15 | TROTTA, MATTEO | EVP, GM, Dermatology US | ストックオプション | 購入 | 5,921 | $0.00 |
| 2024-07-15 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 購入 | 22,205 | $0.00 |
| 2024-07-15 | DENTON, SHEILA A. | EVP & General Counsel | ストックオプション | 購入 | 13,323 | $0.00 |
| 2024-07-15 | DENTON, SHEILA A. | EVP & General Counsel | 普通株式 | 購入 | 5,955 | $0.00 |
| 2024-07-15 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 16,284 | $0.00 |
| 2024-07-15 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 549 | $64.25 |
| 2024-07-15 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 7,278 | $0.00 |
| 2024-07-15 | TRAY, THOMAS | Principal Accounting Officer | ストックオプション | 購入 | 3,783 | $0.00 |
| 2024-07-15 | TRAY, THOMAS | Principal Accounting Officer | 普通株式 | 売却 | 466 | $64.25 |
| 2024-07-15 | TRAY, THOMAS | Principal Accounting Officer | 普通株式 | 購入 | 5,073 | $0.00 |
| 2024-07-15 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 購入 | 31,088 | $0.00 |
| 2024-07-09 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 8,148 | $60.00 |
| 2024-07-02 | IYENGAR, VIJAY K | EVP, GMAPPS | 普通株式 | 売却 | 5,706 | $59.02 |
| 2024-07-02 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 8,316 | $59.02 |
| 2024-07-02 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 5,560 | $59.02 |
| 2024-07-02 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | 普通株式 | 売却 | 6,870 | $59.02 |
| 2024-07-02 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 7,695 | $59.02 |
| 2024-07-02 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 売却 | 41,723 | $59.02 |
| 2024-07-02 | TRAY, THOMAS | Principal Accounting Officer | 普通株式 | 売却 | 844 | $59.02 |
| 2024-06-28 | CLANCY, PAUL J | Director | 普通株式 | 購入 | 399 | $60.62 |
| 2024-06-28 | HARRIGAN, EDMUND | Director | 普通株式 | 購入 | 409 | $60.62 |
| 2024-06-28 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 537 | $0.00 |
| 2024-06-12 | HIGH, KATHERINE A | Director | ストックオプション | 購入 | 12,517 | $0.00 |
| 2024-06-12 | CLANCY, PAUL J | Director | ストックオプション | 購入 | 12,517 | $0.00 |
| 2024-06-12 | BIENAIME, JEAN JACQUES | Director | ストックオプション | 購入 | 12,517 | $0.00 |
| 2024-06-12 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 2,830 | $0.00 |
| 2024-06-12 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 19,164 | $60.00 |
| 2024-06-12 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | ストックオプション | 購入 | 12,517 | $0.00 |
| 2024-06-12 | HARRIGAN, EDMUND | Director | ストックオプション | 購入 | 12,517 | $0.00 |
| 2024-06-12 | HARRIGAN, EDMUND | Director | 普通株式 | 購入 | 2,830 | $0.00 |
| 2024-06-12 | SCHAFFERT, SUSANNE | Director | ストックオプション | 購入 | 12,517 | $0.00 |
| 2024-06-12 | SCHAFFERT, SUSANNE | Director | 普通株式 | 購入 | 2,830 | $0.00 |
| 2024-06-12 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 売却 | 5,283,206 | $60.00 |
| 2024-06-12 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 売却 | 175,977 | $60.00 |
| 2024-06-12 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 2,830 | $0.00 |
| 2024-06-12 | SCHAFFERT, SUSANNE | Director | 普通株式 | 売却 | 752 | $59.94 |
| 2024-06-12 | BRAWLEY, OTIS W | Director | 普通株式 | 購入 | 2,830 | $0.00 |
| 2024-06-12 | HIGH, KATHERINE A | Director | 普通株式 | 購入 | 2,830 | $0.00 |
| 2024-06-12 | CLANCY, PAUL J | Director | 普通株式 | 購入 | 2,830 | $0.00 |
| 2024-06-12 | BRAWLEY, OTIS W | Director | ストックオプション | 購入 | 12,517 | $0.00 |
| 2024-06-12 | FOUSE, JACQUALYN A | Director | ストックオプション | 購入 | 12,517 | $0.00 |
| 2024-06-12 | FOUSE, JACQUALYN A | Director | 普通株式 | 購入 | 2,830 | $0.00 |
| 2024-06-06 | TRAY, THOMAS | Principal Accounting Officer | 普通株式 | 売却 | 1,093 | $58.91 |
| 2024-05-07 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 15,000 | $49.01 |
| 2024-05-07 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | ストックオプション | 売却 | 15,000 | $0.00 |
| 2024-03-28 | CLANCY, PAUL J | Director | 普通株式 | 購入 | 403 | $56.97 |
| 2024-03-28 | HARRIGAN, EDMUND | Director | 普通株式 | 購入 | 413 | $56.97 |
| 2024-03-28 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 543 | $0.00 |
| 2024-03-25 | TROTTA, MATTEO | EVP, GM, Dermatology US | ストックオプション | 購入 | 21,868 | $0.00 |
| 2024-03-25 | TROTTA, MATTEO | EVP, GM, Dermatology US | 普通株式 | 購入 | 7,828 | $0.00 |
| 2024-02-14 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | 普通株式 | 購入 | 7,377 | $0.00 |
| 2024-02-14 | IYENGAR, VIJAY K | EVP, GMAPPS | 普通株式 | 購入 | 7,377 | $0.00 |
| 2024-02-14 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 7,377 | $0.00 |
| 2024-02-14 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 購入 | 41,577 | $0.00 |
| 2024-02-14 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 購入 | 7,377 | $0.00 |
| 2024-02-14 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 7,377 | $0.00 |
| 2024-02-12 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | 普通株式 | 売却 | 387 | $57.84 |
| 2024-01-22 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 売却 | 108 | $61.50 |
| 2024-01-22 | DICKINSON, JONATHAN ELLIOTT | EVP, General Manager, Europe | 普通株式 | 売却 | 108 | $61.50 |
| 2024-01-19 | DICKINSON, JONATHAN ELLIOTT | EVP, General Manager, Europe | 普通株式 | 売却 | 122 | $61.49 |
| 2024-01-19 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 売却 | 122 | $61.49 |
| 2024-01-18 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 購入 | 11,359 | $61.18 |
| 2024-01-18 | HOPPENOT, HERVE | Director, Chairman / CEO, President | ストックオプション | 購入 | 97,566 | $0.00 |
| 2024-01-18 | DICKINSON, JONATHAN ELLIOTT | EVP, General Manager, Europe | 普通株式 | 購入 | 8,114 | $61.18 |
| 2024-01-18 | TRAY, THOMAS | Principal Accounting Officer | ストックオプション | 購入 | 4,530 | $0.00 |
| 2024-01-18 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 16,018 | $0.00 |
| 2024-01-18 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 購入 | 30,580 | $0.00 |
| 2024-01-18 | IYENGAR, VIJAY K | EVP, GMAPPS | ストックオプション | 購入 | 16,018 | $0.00 |
| 2024-01-18 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | ストックオプション | 購入 | 27,668 | $0.00 |
| 2024-01-18 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 購入 | 21,843 | $0.00 |
| 2024-01-18 | CAGNONI, PABLO J | President, R&D | ストックオプション | 購入 | 21,843 | $0.00 |
| 2024-01-17 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 売却 | 101 | $61.48 |
| 2024-01-17 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 3,675 | $61.48 |
| 2024-01-17 | TRAY, THOMAS | Principal Accounting Officer | 普通株式 | 売却 | 1,021 | $61.48 |
| 2024-01-17 | DICKINSON, JONATHAN ELLIOTT | EVP, General Manager, Europe | 普通株式 | 売却 | 101 | $61.48 |
| 2024-01-16 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 売却 | 101 | $61.34 |
| 2024-01-16 | DICKINSON, JONATHAN ELLIOTT | EVP, General Manager, Europe | 普通株式 | 売却 | 101 | $61.34 |
| 2024-01-03 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 7,365 | $65.51 |
| 2024-01-02 | IYENGAR, VIJAY K | EVP, GMAPPS | 普通株式 | 売却 | 657 | $65.00 |
| 2023-12-29 | CLANCY, PAUL J | Director | 普通株式 | 購入 | 412 | $62.79 |
| 2023-12-29 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 556 | $0.00 |
| 2023-12-29 | HARRIGAN, EDMUND | Director | 普通株式 | 購入 | 423 | $62.79 |
| 2023-12-13 | TRAY, THOMAS | Principal Accounting Officer | 普通株式 | 売却 | 1,067 | $62.37 |
| 2023-12-12 | TRAY, THOMAS | Principal Accounting Officer | 普通株式 | 売却 | 210 | $57.36 |
| 2023-10-02 | DENTON, SHEILA A. | EVP & General Counsel | 普通株式 | 購入 | 26,524 | $0.00 |
| 2023-10-02 | DENTON, SHEILA A. | EVP & General Counsel | ストックオプション | 購入 | 28,725 | $0.00 |
| 2023-09-29 | HARRIGAN, EDMUND | Director | 普通株式 | 購入 | 389 | $57.77 |
| 2023-09-29 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 510 | $0.00 |
| 2023-09-29 | CLANCY, PAUL J | Director | 普通株式 | 購入 | 379 | $57.77 |
| 2023-09-01 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 8,449 | $65.13 |
| 2023-08-01 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 21,511 | $63.28 |
| 2023-07-14 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 13,535 | $0.00 |
| 2023-07-14 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | 普通株式 | 購入 | 12,246 | $0.00 |
| 2023-07-14 | TRAY, THOMAS | Principal Accounting Officer | 普通株式 | 購入 | 6,015 | $0.00 |
| 2023-07-14 | TRAY, THOMAS | Principal Accounting Officer | ストックオプション | 購入 | 4,204 | $0.00 |
| 2023-07-14 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 購入 | 20,275 | $0.00 |
| 2023-07-14 | IYENGAR, VIJAY K | EVP, GMAPPS | 普通株式 | 購入 | 7,089 | $0.00 |
| 2023-07-14 | HOPPENOT, HERVE | Director, Chairman / CEO, President | ストックオプション | 購入 | 90,563 | $0.00 |
| 2023-07-14 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | ストックオプション | 購入 | 25,682 | $0.00 |
| 2023-07-14 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 購入 | 8,056 | $0.00 |
| 2023-07-14 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | ストックオプション | 購入 | 16,896 | $0.00 |
| 2023-07-14 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 7,089 | $0.00 |
| 2023-07-14 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 9,668 | $0.00 |
| 2023-07-14 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 14,868 | $0.00 |
| 2023-07-14 | IYENGAR, VIJAY K | EVP, GMAPPS | ストックオプション | 購入 | 14,868 | $0.00 |
| 2023-07-14 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 購入 | 20,275 | $0.00 |
| 2023-07-14 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 購入 | 9,668 | $0.00 |
| 2023-07-14 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 購入 | 28,385 | $0.00 |
| 2023-07-14 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 購入 | 43,184 | $0.00 |
| 2023-07-14 | CAGNONI, PABLO J | President, R&D | ストックオプション | 購入 | 20,275 | $0.00 |
| 2023-07-14 | CAGNONI, PABLO J | President, R&D | 普通株式 | 購入 | 9,668 | $0.00 |
| 2023-07-03 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 売却 | 43,467 | $62.08 |
| 2023-07-03 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 8,442 | $62.08 |
| 2023-07-03 | IYENGAR, VIJAY K | EVP, GMAPPS | 普通株式 | 売却 | 6,215 | $62.08 |
| 2023-07-03 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | 普通株式 | 売却 | 6,073 | $62.08 |
| 2023-07-03 | TRAY, THOMAS | Principal Accounting Officer | 普通株式 | 売却 | 1,136 | $62.08 |
| 2023-07-03 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 5,783 | $62.08 |
| 2023-07-03 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 6,304 | $62.08 |
| 2023-07-03 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 売却 | 8,468 | $62.08 |
| 2023-07-03 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 売却 | 6,044 | $62.08 |
| 2023-06-30 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 512 | $0.00 |
| 2023-06-30 | CLANCY, PAUL J | Director | 普通株式 | 購入 | 380 | $62.25 |
| 2023-06-30 | HARRIGAN, EDMUND | Director | 普通株式 | 購入 | 390 | $62.25 |
| 2023-06-14 | HIGH, KATHERINE A | Director | 普通株式 | 購入 | 2,505 | $0.00 |
| 2023-06-14 | HIGH, KATHERINE A | Director | ストックオプション | 購入 | 11,294 | $0.00 |
| 2023-06-14 | FOUSE, JACQUALYN A | Director | ストックオプション | 購入 | 11,294 | $0.00 |
| 2023-06-14 | FOUSE, JACQUALYN A | Director | 普通株式 | 購入 | 2,505 | $0.00 |
| 2023-06-14 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | ストックオプション | 購入 | 11,294 | $0.00 |
| 2023-06-14 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 2,505 | $0.00 |
| 2023-06-14 | HARRIGAN, EDMUND | Director | ストックオプション | 購入 | 11,294 | $0.00 |
| 2023-06-14 | BRAWLEY, OTIS W | Director | 普通株式 | 購入 | 2,505 | $0.00 |
| 2023-06-14 | BRAWLEY, OTIS W | Director | ストックオプション | 購入 | 11,294 | $0.00 |
| 2023-06-14 | BIENAIME, JEAN JACQUES | Director | ストックオプション | 購入 | 11,294 | $0.00 |
| 2023-06-14 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 2,505 | $0.00 |
| 2023-06-14 | CLANCY, PAUL J | Director | ストックオプション | 購入 | 11,294 | $0.00 |
| 2023-06-14 | CLANCY, PAUL J | Director | 普通株式 | 購入 | 2,505 | $0.00 |
| 2023-06-14 | SCHAFFERT, SUSANNE | Director | ストックオプション | 購入 | 11,294 | $0.00 |
| 2023-06-14 | SCHAFFERT, SUSANNE | Director | 普通株式 | 売却 | 488 | $61.44 |
| 2023-06-14 | SCHAFFERT, SUSANNE | Director | 普通株式 | 購入 | 2,505 | $0.00 |
| 2023-06-14 | HARRIGAN, EDMUND | Director | 普通株式 | 購入 | 2,505 | $0.00 |
| 2023-06-05 | CAGNONI, PABLO J | President, R&D | 普通株式 | 購入 | 192,400 | $0.00 |
| 2023-06-05 | CAGNONI, PABLO J | President, R&D | 普通株式 | 購入 | 179,613 | $0.00 |
| 2023-03-31 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 429 | $0.00 |
| 2023-03-31 | CLANCY, PAUL J | Director | 普通株式 | 購入 | 318 | $72.27 |
| 2023-03-31 | HARRIGAN, EDMUND | Director | 普通株式 | 購入 | 326 | $72.27 |
| 2023-03-13 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 20,000 | $22.74 |
| 2023-03-13 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | ストックオプション | 売却 | 20,000 | $0.00 |
| 2023-02-16 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 購入 | 3,693 | $65.42 |
| 2023-02-16 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | ストックオプション | 売却 | 3,693 | $0.00 |
| 2023-02-13 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | 普通株式 | 売却 | 848 | $80.08 |
| 2023-02-13 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | 普通株式 | 売却 | 331 | $80.08 |
| 2023-01-31 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 売却 | 802 | $84.06 |
| 2023-01-31 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 802 | $74.78 |
| 2023-01-31 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 802 | $0.00 |
| 2023-01-30 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 12,865 | $0.00 |
| 2023-01-30 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 12,865 | $65.36 |
| 2023-01-30 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 売却 | 12,865 | $84.69 |
| 2023-01-30 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 10,438 | $68.62 |
| 2023-01-30 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 売却 | 10,438 | $84.70 |
| 2023-01-30 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 11,861 | $72.27 |
| 2023-01-30 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 売却 | 11,861 | $84.70 |
| 2023-01-30 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 14,374 | $80.50 |
| 2023-01-30 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 売却 | 14,374 | $84.73 |
| 2023-01-30 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 5,644 | $83.58 |
| 2023-01-30 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 売却 | 5,644 | $85.07 |
| 2023-01-30 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 4,842 | $74.78 |
| 2023-01-30 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 売却 | 4,842 | $84.73 |
| 2023-01-30 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 10,438 | $0.00 |
| 2023-01-30 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 11,861 | $0.00 |
| 2023-01-30 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 14,374 | $0.00 |
| 2023-01-30 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 5,644 | $0.00 |
| 2023-01-30 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 4,842 | $0.00 |
| 2023-01-26 | IYENGAR, VIJAY K | EVP, GMAPPS | 普通株式 | 購入 | 7,000 | $68.62 |
| 2023-01-26 | IYENGAR, VIJAY K | EVP, GMAPPS | 普通株式 | 売却 | 7,000 | $85.00 |
| 2023-01-26 | IYENGAR, VIJAY K | EVP, GMAPPS | ストックオプション | 売却 | 7,000 | $0.00 |
| 2023-01-26 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 売却 | 2,419 | $85.00 |
| 2023-01-20 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 14,194 | $0.00 |
| 2023-01-20 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 購入 | 6,159 | $0.00 |
| 2023-01-20 | DICKINSON, JONATHAN ELLIOTT | EVP, General Manager, Europe | 普通株式 | 購入 | 6,159 | $0.00 |
| 2023-01-20 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 購入 | 4,980 | $0.00 |
| 2023-01-20 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | ストックオプション | 購入 | 16,128 | $0.00 |
| 2023-01-20 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 購入 | 19,354 | $0.00 |
| 2023-01-20 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 購入 | 29,196 | $0.00 |
| 2023-01-20 | HOPPENOT, HERVE | Director, Chairman / CEO, President | ストックオプション | 購入 | 86,449 | $0.00 |
| 2023-01-20 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 4,980 | $0.00 |
| 2023-01-20 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 購入 | 4,980 | $0.00 |
| 2023-01-20 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 購入 | 19,354 | $0.00 |
| 2023-01-20 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 4,980 | $0.00 |
| 2023-01-20 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | ストックオプション | 購入 | 24,515 | $0.00 |
| 2023-01-20 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | 普通株式 | 購入 | 4,980 | $0.00 |
| 2023-01-20 | TRAY, THOMAS | Principal Accounting Officer | ストックオプション | 購入 | 2,968 | $0.00 |
| 2023-01-20 | TRAY, THOMAS | Principal Accounting Officer | 普通株式 | 購入 | 2,833 | $0.00 |
| 2023-01-20 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 購入 | 27,096 | $0.00 |
| 2023-01-20 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 4,980 | $0.00 |
| 2023-01-20 | IYENGAR, VIJAY K | EVP, GMAPPS | ストックオプション | 購入 | 14,194 | $0.00 |
| 2023-01-20 | IYENGAR, VIJAY K | EVP, GMAPPS | 普通株式 | 購入 | 4,980 | $0.00 |
| 2023-01-19 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 売却 | 105 | $83.88 |
| 2023-01-19 | DICKINSON, JONATHAN ELLIOTT | EVP, General Manager, Europe | 普通株式 | 売却 | 105 | $83.88 |
| 2023-01-17 | DICKINSON, JONATHAN ELLIOTT | EVP, General Manager, Europe | 普通株式 | 売却 | 87 | $81.26 |
| 2023-01-17 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 売却 | 87 | $81.26 |
| 2023-01-15 | DICKINSON, JONATHAN ELLIOTT | EVP, General Manager, Europe | 普通株式 | 売却 | 87 | $81.26 |
| 2023-01-15 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 売却 | 87 | $81.26 |
| 2023-01-04 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 売却 | 117 | $79.08 |
| 2023-01-04 | DICKINSON, JONATHAN ELLIOTT | EVP, General Manager, Europe | 普通株式 | 売却 | 117 | $79.08 |
| 2023-01-04 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 28,399 | $79.78 |
| 2022-12-30 | FOUSE, JACQUALYN A | Director | 普通株式 | 購入 | 252 | $80.32 |
| 2022-12-30 | CLANCY, PAUL J | Director | 普通株式 | 購入 | 294 | $80.32 |
| 2022-12-30 | HARRIGAN, EDMUND | Director | 普通株式 | 購入 | 302 | $80.32 |
| 2022-12-30 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 397 | $0.00 |
| 2022-12-23 | IYENGAR, VIJAY K | EVP, GMAPPS | 普通株式 | 売却 | 1,654 | $80.79 |
| 2022-12-23 | IYENGAR, VIJAY K | EVP, GMAPPS | 普通株式 | 売却 | 7,000 | $80.80 |
| 2022-12-23 | IYENGAR, VIJAY K | EVP, GMAPPS | 普通株式 | 購入 | 7,000 | $68.62 |
| 2022-12-23 | IYENGAR, VIJAY K | EVP, GMAPPS | ストックオプション | 売却 | 7,866 | $0.00 |
| 2022-12-23 | IYENGAR, VIJAY K | EVP, GMAPPS | ストックオプション | 売却 | 7,000 | $0.00 |
| 2022-12-23 | IYENGAR, VIJAY K | EVP, GMAPPS | 普通株式 | 売却 | 7,866 | $80.80 |
| 2022-12-23 | IYENGAR, VIJAY K | EVP, GMAPPS | 普通株式 | 購入 | 7,866 | $72.86 |
| 2022-12-23 | IYENGAR, VIJAY K | EVP, GMAPPS | 普通株式 | 売却 | 804 | $80.77 |
| 2022-12-19 | TRAY, THOMAS | Principal Accounting Officer | 普通株式 | 売却 | 1,223 | $82.16 |
| 2022-12-12 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 売却 | 533 | $82.36 |
| 2022-10-19 | HARRIGAN, EDMUND | Director | 普通株式 | 購入 | 165 | $69.59 |
| 2022-10-03 | SCHAFFERT, SUSANNE | Director | ストックオプション | 購入 | 6,751 | $0.00 |
| 2022-10-03 | SCHAFFERT, SUSANNE | Director | 普通株式 | 購入 | 1,625 | $0.00 |
| 2022-09-30 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 457 | $0.00 |
| 2022-09-30 | FOUSE, JACQUALYN A | Director | 普通株式 | 購入 | 291 | $66.64 |
| 2022-09-30 | CLANCY, PAUL J | Director | 普通株式 | 購入 | 339 | $66.64 |
| 2022-09-30 | HARRIGAN, EDMUND | Director | 普通株式 | 購入 | 250 | $66.64 |
| 2022-07-22 | TRAY, THOMAS | Principal Accounting Officer | 普通株式 | 売却 | 1,564 | $83.13 |
| 2022-07-07 | IYENGAR, VIJAY K | EVP, GMAPPS | 普通株式 | 売却 | 5,787 | $79.38 |
| 2022-07-07 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 2,873 | $79.38 |
| 2022-07-05 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 2,599 | $79.25 |
| 2022-07-05 | TRAY, THOMAS | Principal Accounting Officer | 普通株式 | 売却 | 987 | $79.25 |
| 2022-07-05 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 3,856 | $79.25 |
| 2022-07-05 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | 普通株式 | 売却 | 1,124 | $79.25 |
| 2022-07-05 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 売却 | 2,181 | $79.25 |
| 2022-07-05 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 売却 | 21,174 | $79.25 |
| 2022-07-05 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 3,506 | $79.25 |
| 2022-07-05 | IYENGAR, VIJAY K | EVP, GMAPPS | 普通株式 | 売却 | 2,599 | $79.25 |
| 2022-07-05 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 売却 | 3,043 | $79.25 |
| 2022-07-02 | TRAY, THOMAS | Principal Accounting Officer | 普通株式 | 購入 | 4,149 | $0.00 |
| 2022-07-02 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 13,529 | $0.00 |
| 2022-07-02 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 13,443 | $0.00 |
| 2022-07-02 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 9,921 | $0.00 |
| 2022-07-02 | TRAY, THOMAS | Principal Accounting Officer | ストックオプション | 購入 | 2,810 | $0.00 |
| 2022-07-02 | IYENGAR, VIJAY K | EVP, GMAPPS | 普通株式 | 購入 | 9,921 | $0.00 |
| 2022-07-02 | IYENGAR, VIJAY K | EVP, GMAPPS | ストックオプション | 購入 | 13,443 | $0.00 |
| 2022-07-02 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 購入 | 60,433 | $0.00 |
| 2022-07-02 | HOPPENOT, HERVE | Director, Chairman / CEO, President | ストックオプション | 購入 | 81,885 | $0.00 |
| 2022-07-02 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 購入 | 13,529 | $0.00 |
| 2022-07-02 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 購入 | 18,332 | $0.00 |
| 2022-07-02 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 購入 | 11,274 | $0.00 |
| 2022-07-02 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | ストックオプション | 購入 | 23,221 | $0.00 |
| 2022-07-02 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | 普通株式 | 購入 | 17,317 | $0.00 |
| 2022-07-02 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 購入 | 25,665 | $0.00 |
| 2022-07-02 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 18,941 | $0.00 |
| 2022-07-02 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | ストックオプション | 購入 | 15,277 | $0.00 |
| 2022-07-02 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 購入 | 18,332 | $0.00 |
| 2022-06-30 | HARRIGAN, EDMUND | Director | 普通株式 | 購入 | 236 | $75.97 |
| 2022-06-30 | FOUSE, JACQUALYN A | Director | 普通株式 | 購入 | 275 | $75.97 |
| 2022-06-30 | CLANCY, PAUL J | Director | 普通株式 | 購入 | 321 | $75.97 |
| 2022-06-30 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 433 | $0.00 |
| 2022-06-28 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 11,488 | $75.63 |
| 2022-06-15 | BIENAIME, JEAN JACQUES | Director | ストックオプション | 購入 | 9,124 | $0.00 |
| 2022-06-15 | FOUSE, JACQUALYN A | Director | ストックオプション | 購入 | 9,124 | $0.00 |
| 2022-06-15 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 2,144 | $0.00 |
| 2022-06-15 | CLANCY, PAUL J | Director | 普通株式 | 購入 | 2,144 | $0.00 |
| 2022-06-15 | BRAWLEY, OTIS W | Director | ストックオプション | 購入 | 9,124 | $0.00 |
| 2022-06-15 | HIGH, KATHERINE A | Director | 普通株式 | 購入 | 2,144 | $0.00 |
| 2022-06-15 | HIGH, KATHERINE A | Director | ストックオプション | 購入 | 9,124 | $0.00 |
| 2022-06-15 | FOUSE, JACQUALYN A | Director | 普通株式 | 購入 | 2,144 | $0.00 |
| 2022-06-15 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | ストックオプション | 購入 | 9,124 | $0.00 |
| 2022-06-15 | CLANCY, PAUL J | Director | ストックオプション | 購入 | 9,124 | $0.00 |
| 2022-06-15 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 2,144 | $0.00 |
| 2022-06-15 | BRAWLEY, OTIS W | Director | 普通株式 | 購入 | 2,144 | $0.00 |
| 2022-06-15 | HARRIGAN, EDMUND | Director | 普通株式 | 購入 | 2,144 | $0.00 |
| 2022-06-15 | HARRIGAN, EDMUND | Director | ストックオプション | 購入 | 9,124 | $0.00 |
| 2022-04-09 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 売却 | 517 | $80.95 |
| 2022-04-08 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 21,348 | $84.00 |
| 2022-04-08 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 購入 | 20,516 | $68.62 |
| 2022-04-08 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 20,516 | $83.01 |
| 2022-04-08 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 購入 | 21,348 | $72.27 |
| 2022-04-08 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 881 | $82.96 |
| 2022-04-08 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 1,248 | $82.96 |
| 2022-04-08 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 売却 | 20,516 | $0.00 |
| 2022-04-08 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 売却 | 21,348 | $0.00 |
| 2022-03-31 | HARRIGAN, EDMUND | Director | 普通株式 | 購入 | 240 | $79.42 |
| 2022-03-31 | FOUSE, JACQUALYN A | Director | 普通株式 | 購入 | 280 | $79.42 |
| 2022-03-31 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 440 | $0.00 |
| 2022-03-31 | DIXON, WENDY L | Director | 普通株式 | 購入 | 249 | $79.42 |
| 2022-03-31 | CLANCY, PAUL J | Director | 普通株式 | 購入 | 326 | $79.42 |
| 2022-03-10 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 2,070 | $71.90 |
| 2022-03-10 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 14,490 | $73.31 |
| 2022-03-10 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 84 | $71.95 |
| 2022-03-10 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 25,107 | $71.90 |
| 2022-03-10 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 175,795 | $73.31 |
| 2022-03-10 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 1,017 | $71.95 |
| 2022-03-09 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 5,370 | $71.72 |
| 2022-03-09 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 65,147 | $71.72 |
| 2022-03-08 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 20,000 | $22.05 |
| 2022-03-08 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 92,385 | $70.68 |
| 2022-03-08 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | ストックオプション | 売却 | 20,000 | $0.00 |
| 2022-03-08 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 7,615 | $70.68 |
| 2022-02-22 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 92,234 | $68.07 |
| 2022-02-22 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 7,566 | $68.07 |
| 2022-02-18 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 100,731 | $68.37 |
| 2022-02-18 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 22,178 | $68.43 |
| 2022-02-18 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 8,296 | $68.37 |
| 2022-02-18 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 1,827 | $68.43 |
| 2022-02-17 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 7,300 | $67.40 |
| 2022-02-17 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 285,672 | $67.74 |
| 2022-02-14 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 182,326 | $66.04 |
| 2022-02-14 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 320,526 | $66.02 |
| 2022-02-11 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 10,985 | $66.95 |
| 2022-02-11 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 265,522 | $66.81 |
| 2022-02-11 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | 普通株式 | 売却 | 846 | $66.76 |
| 2022-02-11 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | 普通株式 | 売却 | 331 | $66.76 |
| 2022-02-10 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 40,164 | $66.57 |
| 2022-02-10 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 6,100 | $67.20 |
| 2022-02-10 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 772,751 | $67.54 |
| 2022-01-31 | DICKINSON, JONATHAN ELLIOTT | EVP, General Manager, Europe | 普通株式 | 売却 | 7,375 | $74.19 |
| 2022-01-24 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 売却 | 78 | $75.34 |
| 2022-01-24 | DICKINSON, JONATHAN ELLIOTT | EVP, General Manager, Europe | 普通株式 | 売却 | 78 | $75.34 |
| 2022-01-19 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 15,054 | $0.00 |
| 2022-01-19 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 購入 | 6,959 | $0.00 |
| 2022-01-19 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 購入 | 15,054 | $0.00 |
| 2022-01-19 | DICKINSON, JONATHAN ELLIOTT | EVP, General Manager, Europe | 普通株式 | 購入 | 6,959 | $0.00 |
| 2022-01-19 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 購入 | 15,054 | $0.00 |
| 2022-01-19 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | ストックオプション | 購入 | 15,054 | $0.00 |
| 2022-01-19 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | ストックオプション | 購入 | 15,054 | $0.00 |
| 2022-01-19 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | ストックオプション | 購入 | 15,054 | $0.00 |
| 2022-01-19 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 購入 | 15,054 | $0.00 |
| 2022-01-19 | HOPPENOT, HERVE | Director, Chairman / CEO, President | ストックオプション | 購入 | 84,852 | $0.00 |
| 2022-01-19 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 購入 | 3,250 | $0.00 |
| 2022-01-18 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 売却 | 101 | $75.01 |
| 2022-01-18 | DICKINSON, JONATHAN ELLIOTT | EVP, General Manager, Europe | 普通株式 | 売却 | 101 | $75.01 |
| 2022-01-07 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 10,870 | $73.31 |
| 2022-01-07 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 10,870 | $73.21 |
| 2022-01-07 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 10,870 | $0.00 |
| 2022-01-04 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 9,319 | $0.00 |
| 2022-01-04 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 売却 | 136 | $71.81 |
| 2022-01-04 | DICKINSON, JONATHAN ELLIOTT | EVP, General Manager, Europe | 普通株式 | 売却 | 136 | $71.81 |
| 2022-01-04 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 9,319 | $73.21 |
| 2022-01-04 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 9,319 | $73.46 |
| 2022-01-03 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 購入 | 1,396 | $73.21 |
| 2022-01-03 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 売却 | 1,396 | $73.31 |
| 2022-01-03 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 売却 | 6,818 | $0.00 |
| 2022-01-03 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 売却 | 1,396 | $0.00 |
| 2022-01-03 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 購入 | 6,818 | $73.21 |
| 2022-01-03 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 売却 | 6,818 | $73.31 |
| 2022-01-01 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 購入 | 8,678 | $0.00 |
| 2022-01-01 | DICKINSON, JONATHAN ELLIOTT | EVP, General Manager, Europe | 普通株式 | 購入 | 3,615 | $0.00 |
| 2022-01-01 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 購入 | 8,678 | $0.00 |
| 2022-01-01 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | 普通株式 | 購入 | 8,678 | $0.00 |
| 2022-01-01 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 購入 | 3,615 | $0.00 |
| 2022-01-01 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 14,463 | $0.00 |
| 2022-01-01 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | 普通株式 | 購入 | 14,463 | $0.00 |
| 2022-01-01 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 28,926 | $0.00 |
| 2022-01-01 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 8,678 | $0.00 |
| 2021-12-31 | HARRIGAN, EDMUND | Director | 普通株式 | 購入 | 253 | $73.40 |
| 2021-12-31 | CLANCY, PAUL J | Director | 普通株式 | 購入 | 343 | $73.40 |
| 2021-12-31 | DIXON, WENDY L | Director | 普通株式 | 購入 | 260 | $73.40 |
| 2021-12-31 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 419 | $0.00 |
| 2021-12-31 | FOUSE, JACQUALYN A | Director | 普通株式 | 購入 | 289 | $73.40 |
| 2021-12-23 | DIXON, WENDY L | Director | 普通株式 | 購入 | 20,000 | $73.25 |
| 2021-12-23 | DIXON, WENDY L | Director | ストックオプション | 売却 | 20,000 | $0.00 |
| 2021-12-23 | DIXON, WENDY L | Director | 普通株式 | 売却 | 20,000 | $22.05 |
| 2021-12-17 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 881,875 | $72.77 |
| 2021-12-17 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 193,997 | $72.91 |
| 2021-12-16 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 139,612 | $71.96 |
| 2021-12-16 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 29,703 | $72.00 |
| 2021-12-15 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 36,476 | $69.63 |
| 2021-12-15 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 9,893 | $70.24 |
| 2021-12-15 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 5,382 | $71.03 |
| 2021-12-15 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 288,368 | $71.91 |
| 2021-12-15 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 861 | $67.90 |
| 2021-12-15 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 9,352 | $68.52 |
| 2021-12-10 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 売却 | 533 | $65.40 |
| 2021-11-19 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 2,355 | $0.00 |
| 2021-11-19 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 379 | $0.00 |
| 2021-11-19 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 2,355 | $0.00 |
| 2021-11-19 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 379 | $0.00 |
| 2021-11-19 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 2,355 | $0.00 |
| 2021-11-19 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | 普通株式 | 購入 | 379 | $0.00 |
| 2021-11-19 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | 普通株式 | 購入 | 2,355 | $0.00 |
| 2021-11-19 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 379 | $0.00 |
| 2021-11-19 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | 普通株式 | 購入 | 379 | $0.00 |
| 2021-11-19 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | 普通株式 | 購入 | 2,355 | $0.00 |
| 2021-11-19 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 購入 | 2,227 | $0.00 |
| 2021-11-19 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 購入 | 13,279 | $0.00 |
| 2021-11-19 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 購入 | 379 | $0.00 |
| 2021-11-19 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 購入 | 2,355 | $0.00 |
| 2021-11-19 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 購入 | 379 | $0.00 |
| 2021-11-19 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 購入 | 2,355 | $0.00 |
| 2021-10-01 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 売却 | 389 | $68.67 |
| 2021-09-30 | FOUSE, JACQUALYN A | Director | 普通株式 | 購入 | 271 | $68.78 |
| 2021-09-30 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 393 | $0.00 |
| 2021-09-30 | HARRIGAN, EDMUND | Director | 普通株式 | 購入 | 237 | $68.78 |
| 2021-09-30 | CLANCY, PAUL J | Director | 普通株式 | 購入 | 321 | $68.78 |
| 2021-09-30 | DIXON, WENDY L | Director | 普通株式 | 購入 | 244 | $68.78 |
| 2021-09-27 | BRAWLEY, OTIS W | Director | 普通株式 | 購入 | 1,255 | $0.00 |
| 2021-09-27 | BRAWLEY, OTIS W | Director | ストックオプション | 購入 | 5,910 | $0.00 |
| 2021-09-24 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 382 | $65.36 |
| 2021-09-24 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 382 | $0.00 |
| 2021-09-20 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 1,356 | $0.00 |
| 2021-09-20 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 1,356 | $73.21 |
| 2021-09-01 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 売却 | 388 | $76.71 |
| 2021-08-02 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 売却 | 389 | $77.49 |
| 2021-07-29 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | 普通株式 | 売却 | 4,911 | $78.29 |
| 2021-07-06 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | 普通株式 | 売却 | 401 | $83.34 |
| 2021-07-06 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 売却 | 1,562 | $83.34 |
| 2021-07-06 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 273 | $83.34 |
| 2021-07-06 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 売却 | 104 | $83.34 |
| 2021-07-06 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 402 | $83.34 |
| 2021-07-06 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 273 | $83.34 |
| 2021-07-06 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 売却 | 405 | $83.34 |
| 2021-07-02 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 7,853 | $0.00 |
| 2021-07-02 | WENQING, YAO | EVP, Head of Discovery Chem | ストックオプション | 購入 | 15,054 | $0.00 |
| 2021-07-02 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 売却 | 2,953 | $83.58 |
| 2021-07-02 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 購入 | 7,853 | $0.00 |
| 2021-07-02 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 購入 | 3,250 | $0.00 |
| 2021-07-02 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 売却 | 872 | $83.58 |
| 2021-07-02 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 購入 | 4,521 | $0.00 |
| 2021-07-02 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 購入 | 15,054 | $0.00 |
| 2021-07-02 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 購入 | 44,264 | $0.00 |
| 2021-07-02 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 売却 | 16,089 | $83.58 |
| 2021-07-02 | HOPPENOT, HERVE | Director, Chairman / CEO, President | ストックオプション | 購入 | 84,851 | $0.00 |
| 2021-07-02 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 購入 | 7,853 | $0.00 |
| 2021-07-02 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 1,990 | $83.58 |
| 2021-07-02 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 購入 | 15,054 | $0.00 |
| 2021-07-02 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 購入 | 7,853 | $0.00 |
| 2021-07-02 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 売却 | 1,573 | $83.58 |
| 2021-07-02 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | ストックオプション | 購入 | 15,054 | $0.00 |
| 2021-07-02 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | 普通株式 | 売却 | 1,990 | $83.58 |
| 2021-07-02 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | 普通株式 | 購入 | 7,853 | $0.00 |
| 2021-07-02 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 売却 | 2,241 | $83.58 |
| 2021-07-02 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 7,853 | $0.00 |
| 2021-07-02 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | ストックオプション | 購入 | 15,054 | $0.00 |
| 2021-07-02 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | 普通株式 | 売却 | 516 | $0.00 |
| 2021-07-02 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | 普通株式 | 購入 | 7,853 | $0.00 |
| 2021-07-02 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 15,054 | $0.00 |
| 2021-07-02 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 1,990 | $83.58 |
| 2021-07-02 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 7,853 | $0.00 |
| 2021-07-02 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 購入 | 15,054 | $0.00 |
| 2021-07-02 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 2,953 | $83.58 |
| 2021-07-02 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | ストックオプション | 購入 | 15,054 | $0.00 |
| 2021-07-01 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 売却 | 396 | $84.09 |
| 2021-06-30 | CLANCY, PAUL J | Director | 普通株式 | 購入 | 283 | $84.13 |
| 2021-06-30 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 345 | $0.00 |
| 2021-06-30 | FOUSE, JACQUALYN A | Director | 普通株式 | 購入 | 238 | $84.13 |
| 2021-06-30 | DIXON, WENDY L | Director | 普通株式 | 購入 | 214 | $84.13 |
| 2021-06-30 | HARRIGAN, EDMUND | Director | 普通株式 | 購入 | 208 | $84.13 |
| 2021-06-29 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 売却 | 27,194 | $85.37 |
| 2021-06-28 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 22,079 | $85.61 |
| 2021-06-28 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 売却 | 22,806 | $85.61 |
| 2021-06-18 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 255 | $65.36 |
| 2021-06-18 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 255 | $0.00 |
| 2021-06-10 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | ストックオプション | 売却 | 3,845 | $0.00 |
| 2021-06-10 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 売却 | 3,845 | $87.00 |
| 2021-06-10 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 購入 | 3,845 | $65.42 |
| 2021-06-01 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 売却 | 395 | $84.13 |
| 2021-05-26 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | ストックオプション | 購入 | 8,010 | $0.00 |
| 2021-05-26 | BIENAIME, JEAN JACQUES | Director | ストックオプション | 購入 | 8,010 | $0.00 |
| 2021-05-26 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 1,923 | $0.00 |
| 2021-05-26 | CLANCY, PAUL J | Director | ストックオプション | 購入 | 8,010 | $0.00 |
| 2021-05-26 | CLANCY, PAUL J | Director | 普通株式 | 購入 | 1,923 | $0.00 |
| 2021-05-26 | DIXON, WENDY L | Director | ストックオプション | 購入 | 8,010 | $0.00 |
| 2021-05-26 | DIXON, WENDY L | Director | 普通株式 | 購入 | 1,923 | $0.00 |
| 2021-05-26 | FOUSE, JACQUALYN A | Director | ストックオプション | 購入 | 8,010 | $0.00 |
| 2021-05-26 | FOUSE, JACQUALYN A | Director | 普通株式 | 購入 | 1,923 | $0.00 |
| 2021-05-26 | HARRIGAN, EDMUND | Director | ストックオプション | 購入 | 8,010 | $0.00 |
| 2021-05-26 | HARRIGAN, EDMUND | Director | 普通株式 | 購入 | 1,923 | $0.00 |
| 2021-05-26 | HIGH, KATHERINE A | Director | ストックオプション | 購入 | 8,010 | $0.00 |
| 2021-05-26 | HIGH, KATHERINE A | Director | 普通株式 | 購入 | 1,923 | $0.00 |
| 2021-05-26 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 1,923 | $0.00 |
| 2021-05-14 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | ストックオプション | 売却 | 20,000 | $0.00 |
| 2021-05-14 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 20,000 | $18.97 |
| 2021-05-03 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 売却 | 396 | $85.40 |
| 2021-04-23 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 127 | $65.36 |
| 2021-04-23 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 127 | $0.00 |
| 2021-04-09 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 売却 | 517 | $79.96 |
| 2021-04-01 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 売却 | 396 | $81.57 |
| 2021-03-31 | CLANCY, PAUL J | Director | 普通株式 | 購入 | 298 | $81.27 |
| 2021-03-31 | FOUSE, JACQUALYN A | Director | 普通株式 | 購入 | 251 | $81.27 |
| 2021-03-31 | HARRIGAN, EDMUND | Director | 普通株式 | 購入 | 219 | $81.27 |
| 2021-03-31 | DIXON, WENDY L | Director | 普通株式 | 購入 | 225 | $81.27 |
| 2021-03-31 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 364 | $0.00 |
| 2021-03-29 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 売却 | 20,000 | $81.08 |
| 2021-03-12 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 128 | $65.36 |
| 2021-03-12 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 128 | $0.00 |
| 2021-03-01 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 売却 | 395 | $79.73 |
| 2021-02-23 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 購入 | 12,925 | $77.37 |
| 2021-02-16 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 127 | $65.36 |
| 2021-02-16 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 127 | $0.00 |
| 2021-02-11 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | 普通株式 | 売却 | 1,210 | $84.99 |
| 2021-02-01 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 売却 | 395 | $90.00 |
| 2021-02-01 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 購入 | 961 | $65.42 |
| 2021-02-01 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | ストックオプション | 売却 | 961 | $0.00 |
| 2021-02-01 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 売却 | 961 | $90.00 |
| 2021-01-25 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 2,744 | $100.00 |
| 2021-01-25 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | 普通株式 | 売却 | 1,000 | $99.00 |
| 2021-01-25 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | 普通株式 | 売却 | 4,116 | $99.00 |
| 2021-01-25 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | 普通株式 | 購入 | 4,116 | $72.86 |
| 2021-01-25 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 売却 | 3,795 | $0.00 |
| 2021-01-25 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 3,795 | $100.00 |
| 2021-01-25 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 3,795 | $68.62 |
| 2021-01-25 | WENQING, YAO | EVP, Head of Discovery Chem | ストックオプション | 売却 | 19,986 | $0.00 |
| 2021-01-25 | WENQING, YAO | EVP, Head of Discovery Chem | ストックオプション | 売却 | 1,559 | $0.00 |
| 2021-01-25 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 売却 | 19,986 | $100.00 |
| 2021-01-25 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 購入 | 19,986 | $73.21 |
| 2021-01-25 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 売却 | 1,559 | $100.00 |
| 2021-01-25 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 購入 | 1,559 | $73.21 |
| 2021-01-25 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 売却 | 78 | $100.50 |
| 2021-01-25 | DICKINSON, JONATHAN ELLIOTT | EVP, General Manager, Europe | 普通株式 | 売却 | 78 | $100.50 |
| 2021-01-25 | INCYTE, CORP | 10% Owner | 普通株式 | 購入 | 350,000 | $24.75 |
| 2021-01-25 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | ストックオプション | 売却 | 4,116 | $0.00 |
| 2021-01-19 | DICKINSON, JONATHAN ELLIOTT | EVP, General Manager, Europe | 普通株式 | 売却 | 174 | $93.96 |
| 2021-01-19 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 売却 | 174 | $93.96 |
| 2021-01-15 | HOPPENOT, HERVE | Director, Chairman / CEO, President | ストックオプション | 購入 | 74,720 | $0.00 |
| 2021-01-15 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 購入 | 11,522 | $0.00 |
| 2021-01-15 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 購入 | 5,761 | $0.00 |
| 2021-01-15 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 購入 | 11,522 | $0.00 |
| 2021-01-15 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 購入 | 12,743 | $0.00 |
| 2021-01-15 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | ストックオプション | 購入 | 12,743 | $0.00 |
| 2021-01-15 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 12,743 | $0.00 |
| 2021-01-15 | DICKINSON, JONATHAN ELLIOTT | EVP, General Manager, Europe | 普通株式 | 購入 | 5,761 | $0.00 |
| 2021-01-15 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 購入 | 4,032 | $0.00 |
| 2021-01-15 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 購入 | 12,743 | $0.00 |
| 2021-01-15 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 購入 | 12,743 | $0.00 |
| 2021-01-15 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 23,044 | $0.00 |
| 2021-01-15 | WENQING, YAO | EVP, Head of Discovery Chem | ストックオプション | 購入 | 12,743 | $0.00 |
| 2021-01-15 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 購入 | 11,522 | $0.00 |
| 2021-01-15 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | ストックオプション | 購入 | 12,743 | $0.00 |
| 2021-01-15 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | 普通株式 | 購入 | 11,522 | $0.00 |
| 2021-01-15 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 購入 | 2,534 | $0.00 |
| 2021-01-15 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | ストックオプション | 購入 | 12,743 | $0.00 |
| 2021-01-11 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 127 | $65.36 |
| 2021-01-11 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 127 | $0.00 |
| 2021-01-04 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 売却 | 136 | $86.45 |
| 2021-01-04 | DICKINSON, JONATHAN ELLIOTT | EVP, General Manager, Europe | 普通株式 | 売却 | 136 | $86.45 |
| 2020-12-31 | CLANCY, PAUL J | Director | 普通株式 | 購入 | 281 | $86.98 |
| 2020-12-31 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 343 | $0.00 |
| 2020-12-31 | HARRIGAN, EDMUND | Director | 普通株式 | 購入 | 207 | $86.98 |
| 2020-12-31 | FOUSE, JACQUALYN A | Director | 普通株式 | 購入 | 237 | $86.98 |
| 2020-12-31 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 275 | $86.98 |
| 2020-12-31 | DIXON, WENDY L | Director | 普通株式 | 購入 | 213 | $86.98 |
| 2020-12-11 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 128 | $0.00 |
| 2020-12-11 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 128 | $65.36 |
| 2020-12-10 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 売却 | 720 | $82.05 |
| 2020-11-16 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | 普通株式 | 購入 | 1,232 | $0.00 |
| 2020-11-16 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 購入 | 1,232 | $0.00 |
| 2020-11-16 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 購入 | 1,232 | $0.00 |
| 2020-11-16 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 購入 | 7,225 | $0.00 |
| 2020-11-16 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 1,232 | $0.00 |
| 2020-11-16 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 1,232 | $0.00 |
| 2020-11-16 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 購入 | 1,232 | $0.00 |
| 2020-11-16 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | 普通株式 | 購入 | 1,232 | $0.00 |
| 2020-11-16 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 1,232 | $0.00 |
| 2020-11-12 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 127 | $0.00 |
| 2020-11-12 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 127 | $65.36 |
| 2020-11-10 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 売却 | 798 | $83.00 |
| 2020-11-06 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | ストックオプション | 売却 | 961 | $0.00 |
| 2020-11-06 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 売却 | 961 | $85.17 |
| 2020-11-06 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 購入 | 961 | $65.42 |
| 2020-11-02 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 20,000 | $86.60 |
| 2020-11-02 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 購入 | 20,000 | $48.44 |
| 2020-11-02 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 売却 | 20,000 | $0.00 |
| 2020-10-12 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 128 | $65.36 |
| 2020-10-12 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 128 | $0.00 |
| 2020-10-09 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 1,423 | $0.00 |
| 2020-10-09 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 1,423 | $68.62 |
| 2020-10-09 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 売却 | 1,423 | $95.00 |
| 2020-10-06 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | ストックオプション | 売却 | 961 | $0.00 |
| 2020-10-06 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 売却 | 961 | $91.97 |
| 2020-10-06 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 購入 | 961 | $65.42 |
| 2020-09-30 | DIXON, WENDY L | Director | 普通株式 | 購入 | 197 | $89.74 |
| 2020-09-30 | HARRIGAN, EDMUND | Director | 普通株式 | 購入 | 187 | $89.74 |
| 2020-09-30 | FOUSE, JACQUALYN A | Director | 普通株式 | 購入 | 219 | $89.74 |
| 2020-09-30 | CLANCY, PAUL J | Director | 普通株式 | 購入 | 260 | $89.74 |
| 2020-09-30 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 254 | $89.74 |
| 2020-09-30 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 317 | $0.00 |
| 2020-09-11 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 127 | $65.36 |
| 2020-09-11 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 127 | $0.00 |
| 2020-09-10 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 2,193 | $0.00 |
| 2020-09-10 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 2,193 | $65.36 |
| 2020-09-10 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 売却 | 2,193 | $90.83 |
| 2020-09-08 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 購入 | 961 | $65.42 |
| 2020-09-08 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | ストックオプション | 売却 | 961 | $0.00 |
| 2020-09-08 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 売却 | 961 | $88.94 |
| 2020-08-27 | DIXON, WENDY L | Director | 普通株式 | 購入 | 20,000 | $18.97 |
| 2020-08-27 | DIXON, WENDY L | Director | 普通株式 | 売却 | 20,000 | $94.51 |
| 2020-08-27 | DIXON, WENDY L | Director | ストックオプション | 売却 | 20,000 | $0.00 |
| 2020-08-10 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 128 | $65.36 |
| 2020-08-10 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 128 | $0.00 |
| 2020-08-06 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 売却 | 961 | $97.80 |
| 2020-08-06 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 購入 | 961 | $65.42 |
| 2020-08-06 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | ストックオプション | 売却 | 961 | $0.00 |
| 2020-07-16 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 766 | $103.83 |
| 2020-07-15 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 623 | $104.25 |
| 2020-07-15 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 売却 | 203 | $104.25 |
| 2020-07-15 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 売却 | 639 | $104.25 |
| 2020-07-15 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 626 | $104.25 |
| 2020-07-15 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 639 | $104.25 |
| 2020-07-15 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 売却 | 2,420 | $104.25 |
| 2020-07-13 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | ストックオプション | 売却 | 2,419 | $0.00 |
| 2020-07-13 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 購入 | 2,419 | $65.42 |
| 2020-07-10 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 127 | $0.00 |
| 2020-07-10 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 127 | $65.36 |
| 2020-07-08 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | 普通株式 | 売却 | 475 | $108.56 |
| 2020-07-08 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 610 | $108.56 |
| 2020-07-07 | HOPPENOT, HERVE | Director, Chairman / CEO, President | ストックオプション | 売却 | 1,365 | $0.00 |
| 2020-07-07 | HOPPENOT, HERVE | Director, Chairman / CEO, President | ストックオプション | 売却 | 88,406 | $0.00 |
| 2020-07-07 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 売却 | 7,495 | $0.00 |
| 2020-07-07 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 7,495 | $110.04 |
| 2020-07-07 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 売却 | 1,365 | $110.00 |
| 2020-07-07 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | 普通株式 | 売却 | 3,120 | $107.98 |
| 2020-07-07 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 7,495 | $88.68 |
| 2020-07-07 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 3,381 | $110.04 |
| 2020-07-07 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 3,381 | $88.68 |
| 2020-07-07 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 売却 | 3,381 | $0.00 |
| 2020-07-07 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 購入 | 88,406 | $73.21 |
| 2020-07-07 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 購入 | 1,365 | $73.21 |
| 2020-07-07 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 3,283 | $107.99 |
| 2020-07-07 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 売却 | 88,406 | $110.00 |
| 2020-07-06 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 596 | $107.31 |
| 2020-07-06 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 273 | $107.97 |
| 2020-07-06 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 売却 | 596 | $0.00 |
| 2020-07-06 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 売却 | 10,437 | $0.00 |
| 2020-07-06 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 10,437 | $68.62 |
| 2020-07-06 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 売却 | 12,132 | $0.00 |
| 2020-07-06 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | 普通株式 | 売却 | 404 | $107.79 |
| 2020-07-06 | WENQING, YAO | EVP, Head of Discovery Chem | ストックオプション | 売却 | 15,648 | $0.00 |
| 2020-07-06 | WENQING, YAO | EVP, Head of Discovery Chem | ストックオプション | 売却 | 905 | $0.00 |
| 2020-07-06 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 売却 | 15,648 | $107.32 |
| 2020-07-06 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 購入 | 15,648 | $64.55 |
| 2020-07-06 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 売却 | 104 | $107.79 |
| 2020-07-06 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 売却 | 961 | $106.58 |
| 2020-07-06 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | ストックオプション | 売却 | 961 | $0.00 |
| 2020-07-06 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 10,437 | $107.31 |
| 2020-07-06 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 売却 | 404 | $107.79 |
| 2020-07-06 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 購入 | 905 | $64.55 |
| 2020-07-06 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 売却 | 905 | $107.32 |
| 2020-07-06 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 269 | $107.79 |
| 2020-07-06 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 2,522 | $106.40 |
| 2020-07-06 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 596 | $83.83 |
| 2020-07-06 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 10,437 | $72.27 |
| 2020-07-06 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 購入 | 961 | $65.42 |
| 2020-07-06 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 404 | $107.79 |
| 2020-07-06 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 売却 | 1,559 | $107.79 |
| 2020-07-06 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 12,132 | $83.83 |
| 2020-07-06 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 12,132 | $107.31 |
| 2020-07-02 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 売却 | 2,373 | $106.47 |
| 2020-07-02 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 12,743 | $0.00 |
| 2020-07-02 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 6,661 | $0.00 |
| 2020-07-02 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 1,474 | $106.47 |
| 2020-07-02 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 購入 | 12,743 | $0.00 |
| 2020-07-02 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 1,474 | $106.47 |
| 2020-07-02 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 6,661 | $0.00 |
| 2020-07-02 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 売却 | 564 | $106.47 |
| 2020-07-02 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 売却 | 11,602 | $106.47 |
| 2020-07-02 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 売却 | 1,057 | $106.47 |
| 2020-07-02 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 購入 | 6,661 | $0.00 |
| 2020-07-02 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 購入 | 12,743 | $0.00 |
| 2020-07-02 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 購入 | 3,532 | $0.00 |
| 2020-07-02 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 1,776 | $106.47 |
| 2020-07-02 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 購入 | 6,661 | $0.00 |
| 2020-07-02 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | 普通株式 | 購入 | 6,661 | $0.00 |
| 2020-07-02 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 6,661 | $0.00 |
| 2020-07-02 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | ストックオプション | 購入 | 12,743 | $0.00 |
| 2020-07-02 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | 普通株式 | 購入 | 6,661 | $0.00 |
| 2020-07-02 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | ストックオプション | 購入 | 12,743 | $0.00 |
| 2020-07-02 | WENQING, YAO | EVP, Head of Discovery Chem | ストックオプション | 購入 | 12,743 | $0.00 |
| 2020-07-02 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 購入 | 39,059 | $0.00 |
| 2020-07-02 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | ストックオプション | 購入 | 12,743 | $0.00 |
| 2020-07-02 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | 普通株式 | 売却 | 1,637 | $106.47 |
| 2020-07-02 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 購入 | 6,661 | $0.00 |
| 2020-07-02 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 売却 | 2,187 | $106.47 |
| 2020-07-02 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 購入 | 12,743 | $0.00 |
| 2020-07-02 | HOPPENOT, HERVE | Director, Chairman / CEO, President | ストックオプション | 購入 | 74,720 | $0.00 |
| 2020-06-30 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 294 | $0.00 |
| 2020-06-30 | DIXON, WENDY L | Director | 普通株式 | 購入 | 182 | $103.97 |
| 2020-06-30 | FOUSE, JACQUALYN A | Director | 普通株式 | 購入 | 202 | $103.97 |
| 2020-06-30 | HARRIGAN, EDMUND | Director | 普通株式 | 購入 | 152 | $103.97 |
| 2020-06-30 | CLANCY, PAUL J | Director | 普通株式 | 購入 | 229 | $103.97 |
| 2020-06-30 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 208 | $103.97 |
| 2020-06-26 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 売却 | 119,501 | $102.91 |
| 2020-06-26 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 購入 | 4,647 | $64.55 |
| 2020-06-26 | HOPPENOT, HERVE | Director, Chairman / CEO, President | ストックオプション | 売却 | 119,501 | $0.00 |
| 2020-06-26 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 売却 | 4,647 | $102.91 |
| 2020-06-26 | HOPPENOT, HERVE | Director, Chairman / CEO, President | ストックオプション | 売却 | 4,647 | $0.00 |
| 2020-06-26 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 購入 | 119,501 | $64.55 |
| 2020-06-23 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 売却 | 6,943 | $0.00 |
| 2020-06-23 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 購入 | 6,943 | $64.55 |
| 2020-06-23 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 売却 | 6,943 | $110.00 |
| 2020-06-23 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 400 | $110.00 |
| 2020-06-23 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 売却 | 599 | $0.00 |
| 2020-06-23 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 購入 | 599 | $73.21 |
| 2020-06-22 | DICKINSON, JONATHAN ELLIOTT | EVP, General Manager, Europe | 普通株式 | 売却 | 9,000 | $105.31 |
| 2020-06-19 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 売却 | 1,423 | $100.00 |
| 2020-06-19 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 7,181 | $105.00 |
| 2020-06-19 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 購入 | 7,181 | $73.21 |
| 2020-06-19 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 1,423 | $72.27 |
| 2020-06-19 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 売却 | 7,181 | $0.00 |
| 2020-06-19 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 1,423 | $0.00 |
| 2020-06-19 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | 普通株式 | 購入 | 7,866 | $72.86 |
| 2020-06-19 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | 普通株式 | 売却 | 7,866 | $105.00 |
| 2020-06-19 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | ストックオプション | 売却 | 7,866 | $0.00 |
| 2020-06-18 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 25,000 | $0.00 |
| 2020-06-18 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 購入 | 25,000 | $0.00 |
| 2020-06-17 | INCYTE, CORP | 10% Owner | 普通株式 | 売却 | 141,920 | $3.66 |
| 2020-06-16 | INCYTE, CORP | 10% Owner | 普通株式 | 売却 | 72,080 | $3.66 |
| 2020-06-15 | INCYTE, CORP | 10% Owner | 普通株式 | 売却 | 384,025 | $3.57 |
| 2020-06-12 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 127 | $0.00 |
| 2020-06-12 | INCYTE, CORP | 10% Owner | 普通株式 | 売却 | 9,100 | $3.58 |
| 2020-06-12 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 127 | $65.36 |
| 2020-06-11 | INCYTE, CORP | 10% Owner | 普通株式 | 売却 | 183,875 | $3.77 |
| 2020-06-10 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 1,423 | $68.62 |
| 2020-06-10 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 売却 | 1,423 | $95.00 |
| 2020-06-10 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 2,192 | $65.36 |
| 2020-06-10 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 売却 | 2,192 | $94.19 |
| 2020-06-10 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 1,423 | $0.00 |
| 2020-06-10 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 2,192 | $0.00 |
| 2020-06-08 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 購入 | 961 | $65.42 |
| 2020-06-08 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 売却 | 961 | $91.87 |
| 2020-06-08 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | ストックオプション | 売却 | 961 | $0.00 |
| 2020-05-28 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 1 | $102.55 |
| 2020-05-26 | DIXON, WENDY L | Director | ストックオプション | 購入 | 10,514 | $0.00 |
| 2020-05-26 | BIENAIME, JEAN JACQUES | Director | ストックオプション | 購入 | 10,514 | $0.00 |
| 2020-05-26 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 1,282 | $0.00 |
| 2020-05-26 | CLANCY, PAUL J | Director | ストックオプション | 購入 | 10,514 | $0.00 |
| 2020-05-26 | CLANCY, PAUL J | Director | 普通株式 | 購入 | 1,282 | $0.00 |
| 2020-05-26 | FRIEDMAN, PAUL A | Director | ストックオプション | 購入 | 10,514 | $0.00 |
| 2020-05-26 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 1,282 | $0.00 |
| 2020-05-26 | FOUSE, JACQUALYN A | Director | 普通株式 | 購入 | 1,282 | $0.00 |
| 2020-05-26 | FOUSE, JACQUALYN A | Director | ストックオプション | 購入 | 10,514 | $0.00 |
| 2020-05-26 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | ストックオプション | 購入 | 10,514 | $0.00 |
| 2020-05-26 | DIXON, WENDY L | Director | 普通株式 | 購入 | 1,282 | $0.00 |
| 2020-05-26 | HIGH, KATHERINE A | Director | 普通株式 | 購入 | 1,282 | $0.00 |
| 2020-05-26 | HIGH, KATHERINE A | Director | ストックオプション | 購入 | 10,514 | $0.00 |
| 2020-05-26 | HARRIGAN, EDMUND | Director | 普通株式 | 購入 | 1,282 | $0.00 |
| 2020-05-26 | HARRIGAN, EDMUND | Director | ストックオプション | 購入 | 10,514 | $0.00 |
| 2020-05-26 | FRIEDMAN, PAUL A | Director | 普通株式 | 購入 | 1,282 | $0.00 |
| 2020-05-11 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 128 | $0.00 |
| 2020-05-11 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 128 | $65.36 |
| 2020-05-06 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | ストックオプション | 売却 | 961 | $0.00 |
| 2020-05-06 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 売却 | 961 | $96.84 |
| 2020-05-06 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 購入 | 961 | $65.42 |
| 2020-04-28 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | ストックオプション | 売却 | 20,000 | $ |
| 2020-04-28 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 20,000 | $13.34 |
| 2020-04-17 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 9,488 | $0.00 |
| 2020-04-17 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 購入 | 1,143 | $64.55 |
| 2020-04-17 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 売却 | 1,143 | $100.00 |
| 2020-04-17 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 売却 | 1,143 | $0.00 |
| 2020-04-17 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 購入 | 6,583 | $73.21 |
| 2020-04-17 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 6,583 | $100.00 |
| 2020-04-17 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 売却 | 6,583 | $0.00 |
| 2020-04-17 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 9,488 | $72.27 |
| 2020-04-17 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 売却 | 9,488 | $100.00 |
| 2020-04-16 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 9,488 | $0.00 |
| 2020-04-16 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 9,488 | $68.62 |
| 2020-04-16 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 売却 | 9,488 | $95.00 |
| 2020-04-14 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 売却 | 17,827 | $90.00 |
| 2020-04-14 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 17,827 | $65.36 |
| 2020-04-14 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 17,827 | $0.00 |
| 2020-04-13 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 売却 | 965 | $85.68 |
| 2020-04-13 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 127 | $0.00 |
| 2020-04-13 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 127 | $65.36 |
| 2020-04-09 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 売却 | 517 | $86.81 |
| 2020-04-06 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 購入 | 3,844 | $65.42 |
| 2020-04-06 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 売却 | 1,842 | $85.00 |
| 2020-04-06 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 売却 | 3,844 | $85.00 |
| 2020-04-06 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | ストックオプション | 売却 | 3,844 | $0.00 |
| 2020-03-31 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 392 | $73.23 |
| 2020-03-31 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 1,639 | $64.55 |
| 2020-03-31 | HARRIGAN, EDMUND | Director | 普通株式 | 購入 | 202 | $73.23 |
| 2020-03-31 | FOUSE, JACQUALYN A | Director | 普通株式 | 購入 | 270 | $73.23 |
| 2020-03-31 | DIXON, WENDY L | Director | 普通株式 | 購入 | 243 | $73.23 |
| 2020-03-31 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 690 | $0.00 |
| 2020-03-31 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 690 | $71.44 |
| 2020-03-31 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 236 | $73.23 |
| 2020-03-31 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 1,639 | $71.44 |
| 2020-03-31 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 690 | $64.55 |
| 2020-03-31 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 1,639 | $0.00 |
| 2020-03-31 | CLANCY, PAUL J | Director | 普通株式 | 購入 | 287 | $73.23 |
| 2020-03-31 | BROOKE, PAUL A | Director | 普通株式 | 購入 | 327 | $73.23 |
| 2020-03-26 | HIGH, KATHERINE A | Director | ストックオプション | 購入 | 1,285 | $0.00 |
| 2020-03-26 | HIGH, KATHERINE A | Director | 普通株式 | 購入 | 139 | $0.00 |
| 2020-03-11 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 128 | $0.00 |
| 2020-03-11 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 128 | $65.36 |
| 2020-02-21 | BROOKE, PAUL A | Director | ストックオプション | 売却 | 20,000 | $0.00 |
| 2020-02-21 | BROOKE, PAUL A | Director | 普通株式 | 購入 | 20,000 | $13.34 |
| 2020-02-19 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 2,500 | $80.00 |
| 2020-02-19 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 2,500 | $0.00 |
| 2020-02-19 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 2,500 | $64.55 |
| 2020-02-13 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 購入 | 40,360 | $0.00 |
| 2020-02-13 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | 普通株式 | 購入 | 6,881 | $0.00 |
| 2020-02-13 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 6,881 | $0.00 |
| 2020-02-13 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 購入 | 6,881 | $0.00 |
| 2020-02-13 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 購入 | 6,881 | $0.00 |
| 2020-02-13 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 6,881 | $0.00 |
| 2020-02-13 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 6,881 | $0.00 |
| 2020-02-13 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 購入 | 6,881 | $0.00 |
| 2020-02-11 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | ストックオプション | 購入 | 34,240 | $0.00 |
| 2020-02-11 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | 普通株式 | 売却 | 780 | $76.14 |
| 2020-02-11 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | 普通株式 | 購入 | 4,268 | $76.14 |
| 2020-02-10 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 127 | $0.00 |
| 2020-02-10 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 127 | $65.36 |
| 2020-02-05 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 売却 | 17,542 | $75.97 |
| 2020-02-05 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 購入 | 17,542 | $18.32 |
| 2020-02-05 | WENQING, YAO | EVP, Head of Discovery Chem | ストックオプション | 売却 | 17,542 | $0.00 |
| 2020-01-23 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 売却 | 64 | $78.24 |
| 2020-01-23 | DICKINSON, JONATHAN ELLIOTT | EVP, General Manager, Europe | 普通株式 | 売却 | 64 | $78.24 |
| 2020-01-17 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | ストックオプション | 購入 | 16,428 | $0.00 |
| 2020-01-17 | WENQING, YAO | EVP, Head of Discovery Chem | ストックオプション | 購入 | 16,428 | $0.00 |
| 2020-01-17 | DICKINSON, JONATHAN ELLIOTT | EVP, General Manager, Europe | 普通株式 | 購入 | 5,741 | $0.00 |
| 2020-01-17 | DICKINSON, JONATHAN ELLIOTT | EVP, General Manager, Europe | 普通株式 | 売却 | 59 | $80.50 |
| 2020-01-17 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | ストックオプション | 購入 | 16,428 | $0.00 |
| 2020-01-17 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 16,428 | $0.00 |
| 2020-01-17 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 購入 | 11,482 | $0.00 |
| 2020-01-17 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 購入 | 16,428 | $0.00 |
| 2020-01-17 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 購入 | 2,290 | $0.00 |
| 2020-01-17 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 購入 | 4,018 | $0.00 |
| 2020-01-17 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 購入 | 16,428 | $0.00 |
| 2020-01-17 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 購入 | 5,741 | $0.00 |
| 2020-01-17 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 売却 | 59 | $80.50 |
| 2020-01-17 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 購入 | 16,428 | $0.00 |
| 2020-01-17 | HOPPENOT, HERVE | Director, Chairman / CEO, President | ストックオプション | 購入 | 96,328 | $0.00 |
| 2020-01-15 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 2,500 | $0.00 |
| 2020-01-15 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 2,500 | $64.55 |
| 2020-01-15 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 2,500 | $81.12 |
| 2020-01-10 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 127 | $65.36 |
| 2020-01-10 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 127 | $0.00 |
| 2020-01-06 | MORRISSEY, MICHAEL JAMES | EVP, Head of Tech. Operations | 普通株式 | 売却 | 111 | $77.34 |
| 2020-01-06 | DICKINSON, JONATHAN ELLIOTT | EVP, General Manager, Europe | 普通株式 | 売却 | 111 | $77.34 |
| 2020-01-02 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 売却 | 28,345 | $85.97 |
| 2019-12-31 | BROOKE, PAUL A | Director | 普通株式 | 購入 | 264 | $87.32 |
| 2019-12-31 | DIXON, WENDY L | Director | 普通株式 | 購入 | 196 | $87.32 |
| 2019-12-31 | FOUSE, JACQUALYN A | Director | 普通株式 | 購入 | 218 | $87.32 |
| 2019-12-31 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 316 | $87.32 |
| 2019-12-31 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 190 | $87.32 |
| 2019-12-31 | CLANCY, PAUL J | Director | 普通株式 | 購入 | 231 | $87.32 |
| 2019-12-17 | HARRIGAN, EDMUND | Director | ストックオプション | 購入 | 4,360 | $0.00 |
| 2019-12-17 | HARRIGAN, EDMUND | Director | 普通株式 | 購入 | 462 | $0.00 |
| 2019-12-16 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 2,500 | $64.55 |
| 2019-12-16 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 2,500 | $91.61 |
| 2019-12-16 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 2,500 | $0.00 |
| 2019-12-12 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 77 | $0.00 |
| 2019-12-12 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 77 | $65.36 |
| 2019-12-10 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 売却 | 533 | $95.72 |
| 2019-12-02 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 売却 | 16,835 | $95.00 |
| 2019-12-02 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 売却 | 6,582 | $0.00 |
| 2019-12-02 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 6,582 | $95.00 |
| 2019-12-02 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 購入 | 6,582 | $73.21 |
| 2019-12-02 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | ストックオプション | 売却 | 7,366 | $0.00 |
| 2019-12-02 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | 普通株式 | 売却 | 7,366 | $95.00 |
| 2019-12-02 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | 普通株式 | 購入 | 7,366 | $72.86 |
| 2019-12-02 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 購入 | 16,835 | $18.32 |
| 2019-12-02 | WENQING, YAO | EVP, Head of Discovery Chem | ストックオプション | 売却 | 16,835 | $0.00 |
| 2019-11-29 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | 普通株式 | 購入 | 500 | $72.86 |
| 2019-11-29 | WENQING, YAO | EVP, Head of Discovery Chem | ストックオプション | 売却 | 3,165 | $0.00 |
| 2019-11-29 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 購入 | 600 | $73.21 |
| 2019-11-29 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 600 | $95.00 |
| 2019-11-29 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 売却 | 600 | $0.00 |
| 2019-11-29 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | ストックオプション | 売却 | 500 | $0.00 |
| 2019-11-29 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 購入 | 3,165 | $18.32 |
| 2019-11-29 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 売却 | 3,165 | $95.00 |
| 2019-11-29 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | 普通株式 | 売却 | 500 | $95.00 |
| 2019-11-25 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 購入 | 15,000 | $18.32 |
| 2019-11-25 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 購入 | 422 | $48.44 |
| 2019-11-25 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 422 | $90.00 |
| 2019-11-25 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 購入 | 1,720 | $48.44 |
| 2019-11-25 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 1,720 | $90.00 |
| 2019-11-25 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 売却 | 422 | $0.00 |
| 2019-11-25 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 売却 | 15,000 | $90.00 |
| 2019-11-25 | WENQING, YAO | EVP, Head of Discovery Chem | ストックオプション | 売却 | 15,000 | $0.00 |
| 2019-11-25 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 売却 | 1,720 | $0.00 |
| 2019-11-25 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 購入 | 15,000 | $18.32 |
| 2019-11-25 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 売却 | 15,000 | $90.00 |
| 2019-11-25 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 売却 | 15,000 | $0.00 |
| 2019-11-15 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 2,500 | $64.55 |
| 2019-11-15 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 2,500 | $0.00 |
| 2019-11-15 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 2,500 | $86.46 |
| 2019-11-13 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 76 | $0.00 |
| 2019-11-13 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 76 | $65.36 |
| 2019-11-08 | DIXON, WENDY L | Director | ストックオプション | 売却 | 22,884 | $0.00 |
| 2019-11-08 | DIXON, WENDY L | Director | ストックオプション | 売却 | 18,334 | $0.00 |
| 2019-11-08 | DIXON, WENDY L | Director | 普通株式 | 購入 | 22,884 | $12.46 |
| 2019-11-08 | DIXON, WENDY L | Director | 普通株式 | 売却 | 22,884 | $83.87 |
| 2019-11-08 | DIXON, WENDY L | Director | 普通株式 | 購入 | 18,334 | $12.46 |
| 2019-11-08 | DIXON, WENDY L | Director | 普通株式 | 売却 | 18,334 | $83.87 |
| 2019-11-07 | DIXON, WENDY L | Director | 普通株式 | 売却 | 1,540 | $83.60 |
| 2019-11-07 | DIXON, WENDY L | Director | ストックオプション | 売却 | 1,540 | $0.00 |
| 2019-11-07 | DIXON, WENDY L | Director | 普通株式 | 購入 | 1,540 | $12.46 |
| 2019-11-06 | DIXON, WENDY L | Director | 普通株式 | 購入 | 10,576 | $12.46 |
| 2019-11-06 | DIXON, WENDY L | Director | 普通株式 | 売却 | 10,576 | $84.16 |
| 2019-11-06 | DIXON, WENDY L | Director | ストックオプション | 売却 | 10,576 | $0.00 |
| 2019-11-01 | WENQING, YAO | EVP, Head of Discovery Chem | ストックオプション | 売却 | 7,960 | $0.00 |
| 2019-11-01 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 購入 | 7,960 | $18.32 |
| 2019-11-01 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 購入 | 8,500 | $18.32 |
| 2019-11-01 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 売却 | 8,500 | $85.00 |
| 2019-11-01 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 売却 | 8,500 | $0.00 |
| 2019-11-01 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 売却 | 7,960 | $85.00 |
| 2019-10-30 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 売却 | 50,000 | $0.00 |
| 2019-10-30 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 50,000 | $0.00 |
| 2019-10-29 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | 普通株式 | 売却 | 930 | $85.00 |
| 2019-10-29 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 購入 | 2,040 | $18.32 |
| 2019-10-29 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 売却 | 2,040 | $85.00 |
| 2019-10-29 | WENQING, YAO | EVP, Head of Discovery Chem | ストックオプション | 売却 | 2,040 | $0.00 |
| 2019-10-29 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 購入 | 6,601 | $18.32 |
| 2019-10-29 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 売却 | 6,601 | $80.00 |
| 2019-10-29 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 購入 | 8,399 | $18.32 |
| 2019-10-29 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 売却 | 8,399 | $80.00 |
| 2019-10-29 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 購入 | 1,500 | $18.32 |
| 2019-10-29 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 売却 | 1,500 | $85.00 |
| 2019-10-29 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 売却 | 6,601 | $0.00 |
| 2019-10-29 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 売却 | 8,399 | $0.00 |
| 2019-10-29 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 売却 | 1,500 | $0.00 |
| 2019-10-22 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 2,500 | $80.00 |
| 2019-10-22 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 2,500 | $0.00 |
| 2019-10-22 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 2,500 | $64.55 |
| 2019-10-10 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 77 | $65.36 |
| 2019-10-10 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 77 | $0.00 |
| 2019-09-30 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 219 | $74.23 |
| 2019-09-30 | BROOKE, PAUL A | Director | 普通株式 | 購入 | 304 | $74.23 |
| 2019-09-30 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 364 | $74.23 |
| 2019-09-30 | FOUSE, JACQUALYN A | Director | 普通株式 | 購入 | 251 | $74.23 |
| 2019-09-30 | DIXON, WENDY L | Director | 普通株式 | 購入 | 225 | $74.23 |
| 2019-09-30 | CLANCY, PAUL J | Director | 普通株式 | 購入 | 266 | $74.23 |
| 2019-09-18 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 2,500 | $80.00 |
| 2019-09-18 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 2,500 | $64.55 |
| 2019-09-18 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 2,500 | $0.00 |
| 2019-09-17 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 2,491 | $77.71 |
| 2019-09-09 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 76 | $65.36 |
| 2019-09-09 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 76 | $0.00 |
| 2019-08-15 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 2,500 | $80.96 |
| 2019-08-15 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 2,500 | $0.00 |
| 2019-08-15 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 2,500 | $64.55 |
| 2019-08-09 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 1,223 | $65.36 |
| 2019-08-09 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 売却 | 1,223 | $0.00 |
| 2019-08-06 | FRIEDMAN, PAUL A | Director | 普通株式 | 購入 | 77,934 | $18.32 |
| 2019-08-06 | FRIEDMAN, PAUL A | Director | ストックオプション | 売却 | 77,934 | $0.00 |
| 2019-08-06 | FRIEDMAN, PAUL A | Director | 普通株式 | 売却 | 77,934 | $82.20 |
| 2019-08-02 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 売却 | 377 | $84.73 |
| 2019-08-02 | FRIEDMAN, PAUL A | Director | 普通株式 | 購入 | 22,066 | $18.32 |
| 2019-08-02 | FRIEDMAN, PAUL A | Director | 普通株式 | 売却 | 22,066 | $84.41 |
| 2019-08-02 | FRIEDMAN, PAUL A | Director | ストックオプション | 売却 | 22,066 | $0.00 |
| 2019-08-01 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 売却 | 1,347 | $85.16 |
| 2019-07-17 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 959 | $79.91 |
| 2019-07-15 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 430 | $81.39 |
| 2019-07-15 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 2,500 | $80.00 |
| 2019-07-15 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 2,500 | $64.55 |
| 2019-07-15 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 売却 | 639 | $81.39 |
| 2019-07-15 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 売却 | 2,400 | $81.39 |
| 2019-07-15 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 409 | $81.39 |
| 2019-07-15 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 2,500 | $0.00 |
| 2019-07-15 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 639 | $81.39 |
| 2019-07-15 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 売却 | 291 | $81.39 |
| 2019-07-05 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 273 | $85.28 |
| 2019-07-05 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 売却 | 148 | $85.28 |
| 2019-07-05 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 売却 | 404 | $85.28 |
| 2019-07-05 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 404 | $85.28 |
| 2019-07-05 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 267 | $85.28 |
| 2019-07-05 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | 普通株式 | 売却 | 273 | $85.28 |
| 2019-07-05 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 売却 | 1,552 | $85.28 |
| 2019-07-02 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | 普通株式 | 売却 | 417 | $85.01 |
| 2019-07-02 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | 普通株式 | 購入 | 6,761 | $0.00 |
| 2019-07-02 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 購入 | 16,428 | $0.00 |
| 2019-07-02 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 売却 | 470 | $85.01 |
| 2019-07-02 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 6,761 | $0.00 |
| 2019-07-02 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 購入 | 16,428 | $0.00 |
| 2019-07-02 | WENQING, YAO | EVP, Head of Discovery Chem | ストックオプション | 購入 | 16,428 | $0.00 |
| 2019-07-02 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 売却 | 619 | $85.01 |
| 2019-07-02 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 購入 | 39,648 | $0.00 |
| 2019-07-02 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 購入 | 6,761 | $0.00 |
| 2019-07-02 | HOPPENOT, HERVE | Director, Chairman / CEO, President | ストックオプション | 購入 | 96,327 | $0.00 |
| 2019-07-02 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 売却 | 2,410 | $85.01 |
| 2019-07-02 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 購入 | 2,534 | $0.00 |
| 2019-07-02 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 417 | $85.01 |
| 2019-07-02 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 6,761 | $0.00 |
| 2019-07-02 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 16,428 | $0.00 |
| 2019-07-02 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 619 | $85.01 |
| 2019-07-02 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 6,761 | $0.00 |
| 2019-07-02 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 購入 | 2,289 | $0.00 |
| 2019-07-02 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 売却 | 336 | $85.01 |
| 2019-07-02 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 購入 | 3,770 | $0.00 |
| 2019-07-02 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | ストックオプション | 購入 | 16,428 | $0.00 |
| 2019-07-02 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 購入 | 6,761 | $0.00 |
| 2019-07-02 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 購入 | 16,428 | $0.00 |
| 2019-07-02 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 417 | $85.01 |
| 2019-07-02 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 購入 | 6,761 | $0.00 |
| 2019-07-02 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | ストックオプション | 購入 | 16,428 | $0.00 |
| 2019-06-28 | FOUSE, JACQUALYN A | Director | 普通株式 | 購入 | 203 | $84.96 |
| 2019-06-28 | CLANCY, PAUL J | Director | 普通株式 | 購入 | 237 | $84.96 |
| 2019-06-28 | BROOKE, PAUL A | Director | 普通株式 | 購入 | 291 | $84.96 |
| 2019-06-28 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 195 | $84.96 |
| 2019-06-28 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 310 | $84.96 |
| 2019-06-28 | DIXON, WENDY L | Director | 普通株式 | 購入 | 208 | $84.96 |
| 2019-06-24 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 8,357 | $87.96 |
| 2019-06-17 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 2,500 | $64.55 |
| 2019-06-17 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 2,500 | $0.00 |
| 2019-06-17 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 2,500 | $80.00 |
| 2019-06-06 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 220,141 | $0.00 |
| 2019-06-06 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 売却 | 692,706 | $0.00 |
| 2019-06-06 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 売却 | 1,603,238 | $0.00 |
| 2019-05-09 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | 普通株式 | 売却 | 1,434 | $82.02 |
| 2019-04-26 | DIXON, WENDY L | Director | ストックオプション | 購入 | 12,472 | $0.00 |
| 2019-04-26 | DIXON, WENDY L | Director | 普通株式 | 購入 | 1,520 | $0.00 |
| 2019-04-26 | FOUSE, JACQUALYN A | Director | ストックオプション | 購入 | 12,472 | $0.00 |
| 2019-04-26 | FOUSE, JACQUALYN A | Director | 普通株式 | 購入 | 1,520 | $0.00 |
| 2019-04-26 | FRIEDMAN, PAUL A | Director | ストックオプション | 購入 | 12,472 | $0.00 |
| 2019-04-26 | FRIEDMAN, PAUL A | Director | 普通株式 | 購入 | 1,520 | $0.00 |
| 2019-04-26 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | ストックオプション | 購入 | 12,472 | $0.00 |
| 2019-04-26 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 1,520 | $0.00 |
| 2019-04-26 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 1,520 | $0.00 |
| 2019-04-26 | BROOKE, PAUL A | Director | 普通株式 | 購入 | 1,520 | $0.00 |
| 2019-04-26 | CLANCY, PAUL J | Director | ストックオプション | 購入 | 12,472 | $0.00 |
| 2019-04-26 | CLANCY, PAUL J | Director | 普通株式 | 購入 | 1,520 | $0.00 |
| 2019-04-26 | BROOKE, PAUL A | Director | ストックオプション | 購入 | 12,472 | $0.00 |
| 2019-04-26 | BIENAIME, JEAN JACQUES | Director | ストックオプション | 購入 | 12,472 | $0.00 |
| 2019-04-09 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 売却 | 517 | $82.73 |
| 2019-04-01 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 8,218 | $18.32 |
| 2019-04-01 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 1,782 | $18.32 |
| 2019-04-01 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 1,782 | $87.01 |
| 2019-04-01 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 1,782 | $0.00 |
| 2019-04-01 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 8,218 | $0.00 |
| 2019-04-01 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 8,218 | $87.01 |
| 2019-03-29 | BROOKE, PAUL A | Director | 普通株式 | 購入 | 276 | $86.01 |
| 2019-03-29 | CLANCY, PAUL J | Director | 普通株式 | 購入 | 203 | $86.01 |
| 2019-03-29 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 220 | $86.01 |
| 2019-03-29 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 168 | $86.01 |
| 2019-03-29 | FOUSE, JACQUALYN A | Director | 普通株式 | 購入 | 145 | $86.01 |
| 2019-03-29 | DIXON, WENDY L | Director | 普通株式 | 購入 | 188 | $86.01 |
| 2019-03-01 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 10,000 | $18.32 |
| 2019-03-01 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 10,000 | $0.00 |
| 2019-03-01 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 10,000 | $86.68 |
| 2019-02-26 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | ストックオプション | 売却 | 20,000 | $0.00 |
| 2019-02-26 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 20,000 | $2.80 |
| 2019-02-14 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 5,389 | $0.00 |
| 2019-02-14 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 5,389 | $0.00 |
| 2019-02-14 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 購入 | 20,971 | $0.00 |
| 2019-02-14 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 購入 | 5,389 | $0.00 |
| 2019-02-14 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | 普通株式 | 購入 | 5,389 | $0.00 |
| 2019-02-14 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 5,389 | $0.00 |
| 2019-02-14 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 購入 | 5,389 | $0.00 |
| 2019-02-11 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | 普通株式 | 購入 | 10,285 | $80.21 |
| 2019-02-11 | STAMOULIS, CHRISTIANA | EVP & Chief Financial Officer | ストックオプション | 購入 | 72,809 | $0.00 |
| 2019-02-01 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 10,000 | $81.19 |
| 2019-02-01 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 10,000 | $0.00 |
| 2019-02-01 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 10,000 | $18.32 |
| 2019-01-28 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 1,000 | $80.00 |
| 2019-01-17 | WENQING, YAO | EVP, Head of Discovery Chem | ストックオプション | 売却 | 15,354 | $0.00 |
| 2019-01-17 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 売却 | 15,354 | $77.61 |
| 2019-01-17 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 購入 | 15,354 | $17.79 |
| 2019-01-15 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 売却 | 5,813 | $0.00 |
| 2019-01-15 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 購入 | 5,813 | $17.79 |
| 2019-01-15 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 売却 | 5,813 | $75.00 |
| 2019-01-08 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 1,714 | $75.56 |
| 2019-01-07 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 購入 | 10,000 | $17.79 |
| 2019-01-07 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 売却 | 10,000 | $75.00 |
| 2019-01-07 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 売却 | 9,187 | $75.00 |
| 2019-01-07 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 購入 | 9,187 | $17.79 |
| 2019-01-07 | WENQING, YAO | EVP, Head of Discovery Chem | ストックオプション | 売却 | 10,000 | $0.00 |
| 2019-01-07 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 売却 | 808 | $74.21 |
| 2019-01-07 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 売却 | 272 | $74.21 |
| 2019-01-07 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 896 | $74.21 |
| 2019-01-07 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 売却 | 9,187 | $0.00 |
| 2019-01-07 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 売却 | 4,604 | $74.21 |
| 2019-01-07 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 1,200 | $74.21 |
| 2019-01-07 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 847 | $74.21 |
| 2019-01-04 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 購入 | 6,298 | $0.00 |
| 2019-01-04 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 購入 | 7,377 | $0.00 |
| 2019-01-04 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 30,000 | $18.32 |
| 2019-01-04 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 30,000 | $70.00 |
| 2019-01-04 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 22,772 | $0.00 |
| 2019-01-04 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 31,552 | $0.00 |
| 2019-01-04 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 30,000 | $0.00 |
| 2019-01-04 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 購入 | 22,772 | $0.00 |
| 2019-01-04 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 購入 | 22,772 | $0.00 |
| 2019-01-04 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | ストックオプション | 購入 | 22,772 | $0.00 |
| 2019-01-04 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | ストックオプション | 購入 | 31,552 | $0.00 |
| 2019-01-04 | HOPPENOT, HERVE | Director, Chairman / CEO, President | ストックオプション | 購入 | 88,558 | $0.00 |
| 2019-01-04 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 購入 | 63,105 | $0.00 |
| 2019-01-04 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 購入 | 22,772 | $0.00 |
| 2019-01-04 | WENQING, YAO | EVP, Head of Discovery Chem | ストックオプション | 購入 | 22,772 | $0.00 |
| 2019-01-02 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 売却 | 27,630 | $63.56 |
| 2018-12-31 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 298 | $63.59 |
| 2018-12-31 | DIXON, WENDY L | Director | 普通株式 | 購入 | 255 | $63.59 |
| 2018-12-31 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 228 | $63.59 |
| 2018-12-31 | FOUSE, JACQUALYN A | Director | 普通株式 | 購入 | 196 | $63.59 |
| 2018-12-31 | BROOKE, PAUL A | Director | 普通株式 | 購入 | 373 | $63.59 |
| 2018-12-10 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | 普通株式 | 購入 | 6,878 | $0.00 |
| 2018-12-10 | DHANAK, DASHYANT | EVP & Chief Scientific Officer | ストックオプション | 購入 | 48,403 | $0.00 |
| 2018-11-08 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 500 | $68.91 |
| 2018-11-08 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 500 | $68.62 |
| 2018-10-03 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 1,000 | $70.00 |
| 2018-10-03 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 10,000 | $0.00 |
| 2018-10-03 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 10,000 | $70.00 |
| 2018-10-03 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 10,000 | $18.32 |
| 2018-10-03 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 購入 | 10,000 | $17.79 |
| 2018-10-03 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 売却 | 10,000 | $0.00 |
| 2018-10-03 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 売却 | 10,000 | $70.00 |
| 2018-09-28 | BROOKE, PAUL A | Director | 普通株式 | 購入 | 343 | $69.08 |
| 2018-09-28 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 275 | $69.08 |
| 2018-09-28 | FOUSE, JACQUALYN A | Director | 普通株式 | 購入 | 180 | $69.08 |
| 2018-09-28 | DIXON, WENDY L | Director | 普通株式 | 購入 | 235 | $69.08 |
| 2018-09-28 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 209 | $69.08 |
| 2018-09-04 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 10,000 | $18.32 |
| 2018-09-04 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 10,000 | $73.21 |
| 2018-09-04 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 10,000 | $0.00 |
| 2018-08-21 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 10,000 | $70.00 |
| 2018-08-21 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 10,000 | $0.00 |
| 2018-08-21 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 10,000 | $18.32 |
| 2018-07-16 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 577 | $70.19 |
| 2018-07-16 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 売却 | 196 | $70.19 |
| 2018-07-16 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 639 | $70.19 |
| 2018-07-16 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 売却 | 448 | $70.19 |
| 2018-07-16 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 売却 | 2,359 | $70.19 |
| 2018-07-16 | GRYSKA, DAVID W | Executive Vice President, CFO | 普通株式 | 売却 | 455 | $70.19 |
| 2018-07-16 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 430 | $70.19 |
| 2018-07-16 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 売却 | 430 | $70.19 |
| 2018-07-09 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 10,000 | $18.32 |
| 2018-07-09 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | 普通株式 | 売却 | 606 | $71.34 |
| 2018-07-09 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 10,000 | $0.00 |
| 2018-07-09 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 10,000 | $71.11 |
| 2018-07-05 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 売却 | 1,532 | $68.28 |
| 2018-07-05 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 273 | $68.28 |
| 2018-07-05 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 404 | $68.28 |
| 2018-07-05 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 売却 | 101 | $68.28 |
| 2018-07-05 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 売却 | 273 | $68.28 |
| 2018-07-05 | GRYSKA, DAVID W | Executive Vice President, CFO | 普通株式 | 売却 | 280 | $68.28 |
| 2018-07-05 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 262 | $68.28 |
| 2018-07-05 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 売却 | 284 | $68.28 |
| 2018-07-05 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | 普通株式 | 売却 | 273 | $68.28 |
| 2018-07-02 | GRYSKA, DAVID W | Executive Vice President, CFO | ストックオプション | 購入 | 22,772 | $0.00 |
| 2018-07-02 | HOPPENOT, HERVE | Director, Chairman / CEO, President | ストックオプション | 購入 | 88,557 | $0.00 |
| 2018-07-02 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 22,772 | $0.00 |
| 2018-07-02 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 購入 | 22,772 | $0.00 |
| 2018-07-02 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 購入 | 22,772 | $0.00 |
| 2018-07-02 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 購入 | 2,694 | $0.00 |
| 2018-07-02 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 購入 | 6,297 | $0.00 |
| 2018-07-02 | WENQING, YAO | EVP, Head of Discovery Chem | ストックオプション | 購入 | 22,772 | $0.00 |
| 2018-07-02 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 購入 | 22,772 | $0.00 |
| 2018-07-02 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | ストックオプション | 購入 | 22,772 | $0.00 |
| 2018-07-02 | HUBER, REID M | EVP, Chief Scientific Officer | ストックオプション | 購入 | 22,772 | $0.00 |
| 2018-06-29 | DIXON, WENDY L | Director | 普通株式 | 購入 | 242 | $67.00 |
| 2018-06-29 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 216 | $67.00 |
| 2018-06-29 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 283 | $67.00 |
| 2018-06-29 | BROOKE, PAUL A | Director | 普通株式 | 購入 | 354 | $67.00 |
| 2018-06-29 | FOUSE, JACQUALYN A | Director | 普通株式 | 購入 | 186 | $67.00 |
| 2018-06-20 | BROOKE, PAUL A | Director | 普通株式 | 購入 | 20,000 | $0.00 |
| 2018-06-20 | BROOKE, PAUL A | Director | 普通株式 | 売却 | 20,000 | $0.00 |
| 2018-06-04 | BROOKE, PAUL A | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2018-06-04 | BROOKE, PAUL A | Director | 普通株式 | 購入 | 20,000 | $2.80 |
| 2018-05-04 | BROOKE, PAUL A | Director | 普通株式 | 購入 | 20,000 | $0.00 |
| 2018-05-04 | BROOKE, PAUL A | Director | 普通株式 | 売却 | 20,000 | $0.00 |
| 2018-05-02 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | ストックオプション | 売却 | 20,000 | $0.00 |
| 2018-05-02 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 20,000 | $9.92 |
| 2018-05-02 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 購入 | 15,000 | $60.94 |
| 2018-05-01 | BROOKE, PAUL A | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2018-05-01 | FRIEDMAN, PAUL A | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2018-05-01 | FOUSE, JACQUALYN A | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2018-05-01 | DIXON, WENDY L | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2018-05-01 | CLANCY, PAUL J | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2018-05-01 | BIENAIME, JEAN JACQUES | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2018-05-01 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | ストックオプション | 購入 | 15,000 | $0.00 |
| 2018-04-30 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 73,900 | $0.00 |
| 2018-04-30 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 6,100 | $17.79 |
| 2018-04-30 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 6,100 | $62.43 |
| 2018-04-30 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 73,900 | $17.79 |
| 2018-04-30 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 6,100 | $0.00 |
| 2018-04-30 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 73,900 | $62.43 |
| 2018-04-09 | PASQUALE, MARIA E | EVP & General Counsel | ストックオプション | 購入 | 41,193 | $0.00 |
| 2018-04-09 | PASQUALE, MARIA E | EVP & General Counsel | 普通株式 | 購入 | 5,928 | $0.00 |
| 2018-04-05 | BROOKE, PAUL A | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2018-04-05 | BROOKE, PAUL A | Director | 普通株式 | 購入 | 20,000 | $9.92 |
| 2018-03-29 | FOUSE, JACQUALYN A | Director | 普通株式 | 購入 | 150 | $83.33 |
| 2018-03-29 | BROOKE, PAUL A | Director | 普通株式 | 購入 | 285 | $83.33 |
| 2018-03-29 | DIXON, WENDY L | Director | 普通株式 | 購入 | 195 | $83.33 |
| 2018-03-29 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 174 | $83.33 |
| 2018-03-29 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 228 | $83.33 |
| 2018-03-02 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 2,081 | $86.61 |
| 2018-02-21 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 売却 | 1,958 | $85.55 |
| 2018-02-21 | GRYSKA, DAVID W | Executive Vice President, CFO | 普通株式 | 売却 | 1,952 | $85.56 |
| 2018-02-20 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 売却 | 37,314 | $86.03 |
| 2018-02-20 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 1,026 | $86.03 |
| 2018-02-20 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 1,026 | $86.03 |
| 2018-02-20 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 売却 | 414 | $86.03 |
| 2018-02-20 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 売却 | 1,064 | $86.03 |
| 2018-02-20 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 売却 | 1,026 | $86.03 |
| 2018-02-20 | GRYSKA, DAVID W | Executive Vice President, CFO | 普通株式 | 売却 | 1,070 | $86.03 |
| 2018-01-24 | WENQING, YAO | EVP, Head of Discovery Chem | ストックオプション | 購入 | 21,167 | $0.00 |
| 2018-01-24 | HUBER, REID M | EVP, Chief Scientific Officer | ストックオプション | 購入 | 21,167 | $0.00 |
| 2018-01-24 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 購入 | 21,167 | $0.00 |
| 2018-01-24 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 購入 | 6,491 | $0.00 |
| 2018-01-24 | HOPPENOT, HERVE | Director, Chairman / CEO, President | ストックオプション | 購入 | 25,401 | $0.00 |
| 2018-01-23 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 購入 | 2,755 | $0.00 |
| 2018-01-23 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 12,128 | $0.00 |
| 2018-01-23 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 購入 | 12,128 | $0.00 |
| 2018-01-23 | GRYSKA, DAVID W | Executive Vice President, CFO | ストックオプション | 購入 | 12,128 | $0.00 |
| 2018-01-23 | HOPPENOT, HERVE | Director, Chairman / CEO, President | ストックオプション | 購入 | 47,168 | $0.00 |
| 2018-01-23 | HUBER, REID M | EVP, Chief Scientific Officer | ストックオプション | 購入 | 12,128 | $0.00 |
| 2018-01-23 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | ストックオプション | 購入 | 12,128 | $0.00 |
| 2018-01-23 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 購入 | 12,128 | $0.00 |
| 2018-01-23 | WENQING, YAO | EVP, Head of Discovery Chem | ストックオプション | 購入 | 12,128 | $0.00 |
| 2018-01-05 | GRYSKA, DAVID W | Executive Vice President, CFO | 普通株式 | 購入 | 6,760 | $83.83 |
| 2018-01-05 | GRYSKA, DAVID W | Executive Vice President, CFO | ストックオプション | 売却 | 6,760 | $0.00 |
| 2018-01-05 | GRYSKA, DAVID W | Executive Vice President, CFO | 普通株式 | 売却 | 6,760 | $98.87 |
| 2018-01-02 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | ストックオプション | 売却 | 5,000 | $0.00 |
| 2018-01-02 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | 普通株式 | 購入 | 5,000 | $72.86 |
| 2018-01-02 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | 普通株式 | 売却 | 5,000 | $97.26 |
| 2017-12-29 | DIXON, WENDY L | Director | 普通株式 | 購入 | 171 | $94.71 |
| 2017-12-29 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 153 | $94.71 |
| 2017-12-29 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 200 | $94.71 |
| 2017-12-29 | BROOKE, PAUL A | Director | 普通株式 | 購入 | 250 | $94.71 |
| 2017-12-01 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 売却 | 696 | $98.01 |
| 2017-11-16 | FRIEDMAN, PAUL A | Director | 普通株式 | 売却 | 28,507 | $105.24 |
| 2017-11-14 | FOUSE, JACQUALYN A | Director | ストックオプション | 購入 | 8,750 | $0.00 |
| 2017-11-14 | FOUSE, JACQUALYN A | Director | ストックオプション | 購入 | 25,000 | $0.00 |
| 2017-11-02 | GRYSKA, DAVID W | Executive Vice President, CFO | 普通株式 | 売却 | 3,915 | $105.63 |
| 2017-11-01 | GRYSKA, DAVID W | Executive Vice President, CFO | 普通株式 | 売却 | 3,913 | $107.96 |
| 2017-09-29 | DIXON, WENDY L | Director | 普通株式 | 購入 | 139 | $116.74 |
| 2017-09-29 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 124 | $116.74 |
| 2017-09-29 | BROOKE, PAUL A | Director | 普通株式 | 購入 | 203 | $116.74 |
| 2017-09-29 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 162 | $116.74 |
| 2017-09-18 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 売却 | 70,502 | $119.45 |
| 2017-09-14 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 714 | $124.25 |
| 2017-09-13 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 674 | $123.15 |
| 2017-09-13 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 674 | $123.15 |
| 2017-09-13 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 625 | $123.15 |
| 2017-09-13 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 売却 | 680 | $123.15 |
| 2017-09-13 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 売却 | 692 | $123.15 |
| 2017-09-13 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 売却 | 2,486 | $123.15 |
| 2017-09-13 | GRYSKA, DAVID W | Executive Vice President, CFO | 普通株式 | 売却 | 712 | $123.15 |
| 2017-09-13 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 売却 | 674 | $123.15 |
| 2017-09-08 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 85,402 | $132.00 |
| 2017-09-08 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 2,029 | $132.00 |
| 2017-09-08 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 12,569 | $132.00 |
| 2017-09-05 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 売却 | 3,000 | $0.00 |
| 2017-09-05 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 売却 | 3,000 | $138.41 |
| 2017-09-05 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 購入 | 3,000 | $17.79 |
| 2017-09-01 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 1,820 | $0.00 |
| 2017-09-01 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 1,820 | $64.55 |
| 2017-09-01 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 売却 | 1,820 | $137.40 |
| 2017-08-31 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 20,000 | $0.00 |
| 2017-08-31 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 20,000 | $140.00 |
| 2017-08-31 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 20,000 | $17.79 |
| 2017-08-29 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 522 | $95.76 |
| 2017-08-29 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 1,192 | $88.68 |
| 2017-08-29 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 397 | $83.83 |
| 2017-08-29 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 売却 | 397 | $0.00 |
| 2017-08-29 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 売却 | 1,192 | $0.00 |
| 2017-08-29 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 売却 | 522 | $0.00 |
| 2017-08-29 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 397 | $125.00 |
| 2017-08-29 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 1,192 | $125.00 |
| 2017-08-29 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 522 | $125.00 |
| 2017-08-04 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 売却 | 3,000 | $125.25 |
| 2017-08-04 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 購入 | 3,000 | $17.79 |
| 2017-08-04 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 売却 | 3,000 | $0.00 |
| 2017-08-03 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 売却 | 295 | $125.98 |
| 2017-08-01 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 1,820 | $64.55 |
| 2017-08-01 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 1,820 | $0.00 |
| 2017-08-01 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 売却 | 1,820 | $132.92 |
| 2017-07-20 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 売却 | 522 | $0.00 |
| 2017-07-20 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 1,191 | $88.68 |
| 2017-07-20 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 4,772 | $83.83 |
| 2017-07-20 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 522 | $95.76 |
| 2017-07-20 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 1,191 | $131.09 |
| 2017-07-20 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 売却 | 4,772 | $0.00 |
| 2017-07-20 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 売却 | 1,191 | $0.00 |
| 2017-07-20 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 522 | $131.09 |
| 2017-07-20 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 4,772 | $131.09 |
| 2017-07-05 | GRYSKA, DAVID W | Executive Vice President, CFO | ストックオプション | 購入 | 11,349 | $0.00 |
| 2017-07-05 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 購入 | 11,349 | $0.00 |
| 2017-07-05 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 購入 | 3,000 | $17.79 |
| 2017-07-05 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | 普通株式 | 購入 | 3,517 | $0.00 |
| 2017-07-05 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | ストックオプション | 購入 | 11,349 | $0.00 |
| 2017-07-05 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 3,517 | $0.00 |
| 2017-07-05 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 購入 | 11,349 | $0.00 |
| 2017-07-05 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 3,517 | $0.00 |
| 2017-07-05 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 11,349 | $0.00 |
| 2017-07-05 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 779 | $0.00 |
| 2017-07-05 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 3,517 | $0.00 |
| 2017-07-05 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 購入 | 12,128 | $0.00 |
| 2017-07-05 | GRYSKA, DAVID W | Executive Vice President, CFO | ストックオプション | 購入 | 779 | $0.00 |
| 2017-07-05 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 購入 | 3,517 | $0.00 |
| 2017-07-05 | WENQING, YAO | EVP, Head of Discovery Chem | ストックオプション | 購入 | 12,128 | $0.00 |
| 2017-07-05 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | ストックオプション | 購入 | 779 | $0.00 |
| 2017-07-05 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 購入 | 779 | $0.00 |
| 2017-07-05 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 売却 | 3,000 | $0.00 |
| 2017-07-05 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 購入 | 216 | $0.00 |
| 2017-07-05 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 購入 | 779 | $0.00 |
| 2017-07-05 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 購入 | 2,539 | $0.00 |
| 2017-07-05 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 売却 | 3,000 | $126.18 |
| 2017-07-05 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 購入 | 13,679 | $0.00 |
| 2017-07-05 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 購入 | 3,517 | $0.00 |
| 2017-07-05 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 購入 | 3,517 | $0.00 |
| 2017-07-05 | HUBER, REID M | EVP, Chief Scientific Officer | ストックオプション | 購入 | 12,128 | $0.00 |
| 2017-07-05 | GRYSKA, DAVID W | Executive Vice President, CFO | 普通株式 | 購入 | 3,517 | $0.00 |
| 2017-07-05 | HOPPENOT, HERVE | Director, Chairman / CEO, President | ストックオプション | 購入 | 47,168 | $0.00 |
| 2017-07-05 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 購入 | 1,198 | $0.00 |
| 2017-07-03 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 1,820 | $0.00 |
| 2017-07-03 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 売却 | 1,820 | $126.20 |
| 2017-07-03 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 1,820 | $64.55 |
| 2017-06-30 | DIXON, WENDY L | Director | 普通株式 | 購入 | 129 | $125.91 |
| 2017-06-30 | BROOKE, PAUL A | Director | 普通株式 | 購入 | 188 | $125.91 |
| 2017-06-30 | GRYSKA, DAVID W | Executive Vice President, CFO | 普通株式 | 購入 | 599 | $73.21 |
| 2017-06-30 | GRYSKA, DAVID W | Executive Vice President, CFO | ストックオプション | 売却 | 599 | $0.00 |
| 2017-06-30 | GRYSKA, DAVID W | Executive Vice President, CFO | 普通株式 | 売却 | 599 | $129.74 |
| 2017-06-30 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 115 | $125.91 |
| 2017-06-30 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 150 | $125.91 |
| 2017-06-20 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 6,013 | $125.00 |
| 2017-06-20 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 売却 | 6,013 | $0.00 |
| 2017-06-20 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 売却 | 3,870 | $0.00 |
| 2017-06-20 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 3,870 | $125.00 |
| 2017-06-20 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 6,013 | $88.68 |
| 2017-06-20 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 3,870 | $95.76 |
| 2017-06-12 | GRYSKA, DAVID W | Executive Vice President, CFO | ストックオプション | 売却 | 16,756 | $0.00 |
| 2017-06-12 | GRYSKA, DAVID W | Executive Vice President, CFO | 普通株式 | 売却 | 16,756 | $116.60 |
| 2017-06-12 | GRYSKA, DAVID W | Executive Vice President, CFO | 普通株式 | 購入 | 16,756 | $73.21 |
| 2017-06-06 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 977 | $0.00 |
| 2017-06-06 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 315 | $73.21 |
| 2017-06-06 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 977 | $64.55 |
| 2017-06-06 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 315 | $0.00 |
| 2017-06-05 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 売却 | 3,000 | $132.50 |
| 2017-06-05 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 購入 | 3,000 | $17.79 |
| 2017-06-05 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 売却 | 3,000 | $0.00 |
| 2017-06-01 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 1,820 | $64.55 |
| 2017-06-01 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 売却 | 1,820 | $130.00 |
| 2017-06-01 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 1,820 | $0.00 |
| 2017-05-31 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 500 | $131.80 |
| 2017-05-26 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | ストックオプション | 購入 | 15,000 | $0.00 |
| 2017-05-26 | FRIEDMAN, PAUL A | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2017-05-26 | BIENAIME, JEAN JACQUES | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2017-05-26 | CLANCY, PAUL J | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2017-05-26 | BROOKE, PAUL A | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2017-05-26 | DIXON, WENDY L | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2017-05-15 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 500 | $115.00 |
| 2017-05-08 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 売却 | 8,577 | $119.21 |
| 2017-05-05 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 売却 | 3,000 | $121.70 |
| 2017-05-05 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 売却 | 7,732 | $125.00 |
| 2017-05-05 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 売却 | 4,413 | $125.00 |
| 2017-05-05 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 購入 | 3,000 | $17.79 |
| 2017-05-05 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 売却 | 3,000 | $0.00 |
| 2017-05-01 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 1,820 | $64.55 |
| 2017-05-01 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 1,820 | $0.00 |
| 2017-05-01 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 購入 | 2,064 | $48.44 |
| 2017-05-01 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 803 | $124.61 |
| 2017-05-01 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 4,493 | $124.75 |
| 2017-05-01 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 売却 | 2,064 | $0.00 |
| 2017-05-01 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 売却 | 1,820 | $124.73 |
| 2017-04-28 | GRYSKA, DAVID W | Executive Vice President, CFO | 普通株式 | 売却 | 1,389 | $124.26 |
| 2017-04-28 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 500 | $124.26 |
| 2017-04-28 | GRYSKA, DAVID W | Executive Vice President, CFO | 普通株式 | 購入 | 1,389 | $67.06 |
| 2017-04-28 | GRYSKA, DAVID W | Executive Vice President, CFO | ストックオプション | 売却 | 1,389 | $0.00 |
| 2017-04-27 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | ストックオプション | 売却 | 20,000 | $0.00 |
| 2017-04-27 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 20,000 | $7.26 |
| 2017-04-13 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 1,000 | $139.66 |
| 2017-04-10 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 1,820 | $0.00 |
| 2017-04-10 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 2,223 | $0.00 |
| 2017-04-10 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 売却 | 1,820 | $140.18 |
| 2017-04-10 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 2,223 | $18.32 |
| 2017-04-10 | GRYSKA, DAVID W | Executive Vice President, CFO | 普通株式 | 購入 | 1,739 | $67.06 |
| 2017-04-10 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 売却 | 2,223 | $140.18 |
| 2017-04-10 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 1,820 | $64.55 |
| 2017-04-10 | GRYSKA, DAVID W | Executive Vice President, CFO | ストックオプション | 売却 | 39,789 | $0.00 |
| 2017-04-10 | GRYSKA, DAVID W | Executive Vice President, CFO | ストックオプション | 売却 | 1,739 | $0.00 |
| 2017-04-10 | GRYSKA, DAVID W | Executive Vice President, CFO | 普通株式 | 売却 | 39,789 | $138.00 |
| 2017-04-10 | GRYSKA, DAVID W | Executive Vice President, CFO | 普通株式 | 売却 | 1,739 | $138.00 |
| 2017-04-10 | GRYSKA, DAVID W | Executive Vice President, CFO | 普通株式 | 購入 | 39,789 | $67.06 |
| 2017-04-07 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 5,000 | $95.76 |
| 2017-04-07 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 27,000 | $88.68 |
| 2017-04-07 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 売却 | 5,000 | $0.00 |
| 2017-04-07 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 売却 | 27,000 | $0.00 |
| 2017-04-07 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 5,000 | $137.91 |
| 2017-04-07 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 売却 | 27,000 | $137.88 |
| 2017-04-07 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 1,000 | $139.48 |
| 2017-03-31 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 108 | $133.67 |
| 2017-03-31 | DIXON, WENDY L | Director | 普通株式 | 購入 | 121 | $133.67 |
| 2017-03-31 | BROOKE, PAUL A | Director | 普通株式 | 購入 | 177 | $133.67 |
| 2017-03-31 | BAKER, BROS. ADVISORS LP | Director, 10% Owner | 普通株式 | 購入 | 142 | $133.67 |
| 2017-03-17 | FRIEDMAN, PAUL A | Director | 普通株式 | 売却 | 41,693 | $148.18 |
| 2017-03-17 | FRIEDMAN, PAUL A | Director | 普通株式 | 購入 | 41,693 | $18.32 |
| 2017-03-17 | BROOKE, PAUL A | Director | ストックオプション | 売却 | 20,000 | $0.00 |
| 2017-03-17 | BROOKE, PAUL A | Director | 普通株式 | 購入 | 20,000 | $7.26 |
| 2017-03-17 | BROOKE, PAUL A | Director | 普通株式 | 売却 | 20,000 | $147.75 |
| 2017-03-17 | FRIEDMAN, PAUL A | Director | ストックオプション | 売却 | 41,693 | $0.00 |
| 2017-03-16 | FRIEDMAN, PAUL A | Director | 普通株式 | 売却 | 8,307 | $151.45 |
| 2017-03-16 | FRIEDMAN, PAUL A | Director | ストックオプション | 売却 | 2,849 | $0.00 |
| 2017-03-16 | FRIEDMAN, PAUL A | Director | ストックオプション | 売却 | 5,458 | $0.00 |
| 2017-03-16 | FRIEDMAN, PAUL A | Director | 普通株式 | 購入 | 2,849 | $18.32 |
| 2017-03-16 | FRIEDMAN, PAUL A | Director | 普通株式 | 購入 | 5,458 | $18.32 |
| 2017-02-27 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 売却 | 2,008 | $131.88 |
| 2017-02-24 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 1,182 | $121.95 |
| 2017-02-24 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 売却 | 8,478 | $121.95 |
| 2017-02-24 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 売却 | 418 | $121.95 |
| 2017-02-24 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 売却 | 788 | $121.95 |
| 2017-02-24 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 2,473 | $121.95 |
| 2017-02-24 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 売却 | 1,286 | $121.95 |
| 2017-02-24 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 売却 | 32,443 | $121.95 |
| 2017-02-23 | FRIEDMAN, PAUL A | Director | 普通株式 | 購入 | 50,000 | $18.32 |
| 2017-02-23 | FRIEDMAN, PAUL A | Director | ストックオプション | 売却 | 50,000 | $0.00 |
| 2017-02-23 | FRIEDMAN, PAUL A | Director | 普通株式 | 売却 | 50,000 | $120.32 |
| 2017-02-17 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 4,896,067 | $ |
| 2017-02-17 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 502,779 | $ |
| 2017-02-17 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 491,338 | $ |
| 2017-02-17 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 4,487,412 | $ |
| 2017-02-17 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 売却 | 6,050,000 | $ |
| 2017-02-17 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 売却 | 5,674,000 | $ |
| 2017-02-17 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 売却 | 243,450,000 | $ |
| 2017-02-17 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 売却 | 228,326,000 | $ |
| 2017-02-17 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 売却 | 25,000,000 | $ |
| 2017-02-17 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 売却 | 25,000,000 | $ |
| 2017-02-17 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 121,672 | $ |
| 2017-02-17 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 111,514 | $ |
| 2017-02-14 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 購入 | 6,966 | $0.00 |
| 2017-02-14 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 購入 | 17,428 | $0.00 |
| 2017-02-14 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 3,484 | $0.00 |
| 2017-02-14 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 購入 | 2,322 | $0.00 |
| 2017-02-14 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 3,484 | $0.00 |
| 2017-02-14 | INCYTE, CORP | 10% Owner | 普通株式 | 購入 | 10,000,000 | $6.00 |
| 2017-01-17 | WENQING, YAO | EVP, Head of Discovery Chem | ストックオプション | 購入 | 879 | $0.00 |
| 2017-01-17 | WENQING, YAO | EVP, Head of Discovery Chem | ストックオプション | 購入 | 17,986 | $0.00 |
| 2017-01-17 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 購入 | 879 | $0.00 |
| 2017-01-17 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 購入 | 286 | $0.00 |
| 2017-01-17 | WENQING, YAO | EVP, Head of Discovery Chem | ストックオプション | 購入 | 19,091 | $0.00 |
| 2017-01-17 | HUBER, REID M | EVP, Chief Scientific Officer | ストックオプション | 購入 | 879 | $0.00 |
| 2017-01-17 | GRYSKA, DAVID W | Executive Vice President, CFO | ストックオプション | 購入 | 19,091 | $0.00 |
| 2017-01-17 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 購入 | 19,091 | $0.00 |
| 2017-01-17 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 購入 | 19,091 | $0.00 |
| 2017-01-17 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 19,091 | $0.00 |
| 2017-01-17 | HOPPENOT, HERVE | Director, Chairman / CEO, President | ストックオプション | 購入 | 74,245 | $0.00 |
| 2017-01-17 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 購入 | 17,986 | $0.00 |
| 2017-01-17 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | ストックオプション | 購入 | 879 | $0.00 |
| 2017-01-17 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | ストックオプション | 購入 | 17,986 | $0.00 |
| 2017-01-17 | HOPPENOT, HERVE | Director, Chairman / CEO, President | ストックオプション | 購入 | 879 | $0.00 |
| 2017-01-17 | HOPPENOT, HERVE | Director, Chairman / CEO, President | ストックオプション | 購入 | 93,446 | $0.00 |
| 2017-01-17 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 購入 | 4,906 | $0.00 |
| 2017-01-17 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 購入 | 5,229 | $0.00 |
| 2017-01-17 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 購入 | 879 | $0.00 |
| 2017-01-17 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 購入 | 19,091 | $0.00 |
| 2017-01-17 | HUBER, REID M | EVP, Chief Scientific Officer | ストックオプション | 購入 | 17,986 | $0.00 |
| 2017-01-17 | HUBER, REID M | EVP, Chief Scientific Officer | ストックオプション | 購入 | 19,091 | $0.00 |
| 2017-01-09 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 売却 | 11,739 | $113.55 |
| 2016-12-30 | DIXON, WENDY L | Director | 普通株式 | 購入 | 162 | $100.27 |
| 2016-12-30 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 189 | $100.27 |
| 2016-12-30 | BROOKE, PAUL A | Director | 普通株式 | 購入 | 236 | $100.27 |
| 2016-12-30 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 144 | $100.27 |
| 2016-11-15 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 10,000 | $103.26 |
| 2016-11-15 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 2,317 | $0.00 |
| 2016-11-15 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 7,683 | $0.00 |
| 2016-11-15 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 7,683 | $14.72 |
| 2016-11-15 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 2,317 | $14.72 |
| 2016-11-09 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 売却 | 2,715 | $109.95 |
| 2016-10-20 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 10,000 | $0.00 |
| 2016-10-20 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 10,000 | $14.72 |
| 2016-10-20 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 10,000 | $90.00 |
| 2016-10-07 | HUBER, REID M | EVP, Chief Scientific Officer | ストックオプション | 売却 | 11,709 | $0.00 |
| 2016-10-07 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 売却 | 11,709 | $96.40 |
| 2016-10-07 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 購入 | 11,709 | $18.32 |
| 2016-10-07 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 購入 | 2,408 | $48.44 |
| 2016-10-07 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 購入 | 21,796 | $48.44 |
| 2016-10-07 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 売却 | 24,204 | $97.00 |
| 2016-10-07 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 売却 | 2,408 | $0.00 |
| 2016-10-07 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 売却 | 21,796 | $0.00 |
| 2016-09-30 | DIXON, WENDY L | Director | 普通株式 | 購入 | 172 | $94.29 |
| 2016-09-30 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 201 | $94.29 |
| 2016-09-30 | BROOKE, PAUL A | Director | 普通株式 | 購入 | 251 | $94.29 |
| 2016-09-30 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 153 | $94.29 |
| 2016-09-23 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 20,000 | $90.00 |
| 2016-09-23 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 20,000 | $0.00 |
| 2016-09-23 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 20,000 | $14.72 |
| 2016-08-02 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 売却 | 10,000 | $87.96 |
| 2016-07-29 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 60,000 | $90.00 |
| 2016-07-29 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 60,000 | $14.72 |
| 2016-07-29 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 60,000 | $0.00 |
| 2016-07-15 | WENQING, YAO | EVP, Head of Discovery Chem | 普通株式 | 購入 | 5,555 | $0.00 |
| 2016-07-15 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 購入 | 4,710 | $0.00 |
| 2016-07-15 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 購入 | 2,406 | $0.00 |
| 2016-07-15 | WENQING, YAO | EVP, Head of Discovery Chem | ストックオプション | 購入 | 19,091 | $0.00 |
| 2016-07-15 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 5,555 | $0.00 |
| 2016-07-15 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 18,495 | $0.00 |
| 2016-07-15 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 596 | $0.00 |
| 2016-07-15 | STEIN, STEVEN H | EVP & Chief Medical Officer | 普通株式 | 購入 | 5,555 | $0.00 |
| 2016-07-15 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 購入 | 18,495 | $0.00 |
| 2016-07-15 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 購入 | 21,603 | $0.00 |
| 2016-07-15 | HOPPENOT, HERVE | Director, Chairman / CEO, President | ストックオプション | 購入 | 74,245 | $0.00 |
| 2016-07-15 | GRYSKA, DAVID W | Executive Vice President, CFO | 普通株式 | 購入 | 5,555 | $0.00 |
| 2016-07-15 | GRYSKA, DAVID W | Executive Vice President, CFO | ストックオプション | 購入 | 18,495 | $0.00 |
| 2016-07-15 | GRYSKA, DAVID W | Executive Vice President, CFO | ストックオプション | 購入 | 596 | $0.00 |
| 2016-07-15 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 購入 | 5,555 | $0.00 |
| 2016-07-15 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 購入 | 5,555 | $0.00 |
| 2016-07-15 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 購入 | 18,495 | $0.00 |
| 2016-07-15 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 購入 | 596 | $0.00 |
| 2016-07-15 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 購入 | 805 | $0.00 |
| 2016-07-15 | STEIN, STEVEN H | EVP & Chief Medical Officer | ストックオプション | 購入 | 596 | $0.00 |
| 2016-07-15 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 5,555 | $0.00 |
| 2016-07-15 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 購入 | 18,495 | $0.00 |
| 2016-07-15 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 購入 | 596 | $0.00 |
| 2016-07-15 | HUBER, REID M | EVP, Chief Scientific Officer | ストックオプション | 購入 | 19,091 | $0.00 |
| 2016-06-30 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 181 | $79.98 |
| 2016-06-30 | BROOKE, PAUL A | Director | 普通株式 | 購入 | 296 | $79.98 |
| 2016-06-30 | DIXON, WENDY L | Director | 普通株式 | 購入 | 203 | $79.98 |
| 2016-06-30 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 237 | $79.98 |
| 2016-05-27 | DIXON, WENDY L | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2016-05-27 | CLANCY, PAUL J | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2016-05-27 | BAKER, JULIAN | Director, 10% Owner | ストックオプション | 購入 | 15,000 | $0.00 |
| 2016-05-27 | BROOKE, PAUL A | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2016-05-27 | BIENAIME, JEAN JACQUES | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2016-05-27 | FRIEDMAN, PAUL A | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2016-05-09 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | 普通株式 | 購入 | 4,632 | $0.00 |
| 2016-05-09 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | ストックオプション | 購入 | 28,598 | $0.00 |
| 2016-05-09 | IYENGAR, VIJAY K | EVP GPS, BD, & Licensing | ストックオプション | 購入 | 4,116 | $0.00 |
| 2016-04-01 | BROOKE, PAUL A | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2016-04-01 | BROOKE, PAUL A | Director | 普通株式 | 購入 | 20,000 | $3.86 |
| 2016-03-31 | DIXON, WENDY L | Director | 普通株式 | 購入 | 224 | $72.47 |
| 2016-03-31 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 262 | $72.47 |
| 2016-03-31 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 200 | $72.47 |
| 2016-03-31 | BROOKE, PAUL A | Director | 普通株式 | 購入 | 327 | $72.47 |
| 2016-03-17 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 24,431 | $61.03 |
| 2016-03-17 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 127,964 | $61.38 |
| 2016-03-17 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 9,821 | $62.59 |
| 2016-03-17 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 90,179 | $62.59 |
| 2016-03-17 | BAKER, JULIAN | Director, 10% Owner | ストックオプション | 売却 | 20,000 | $0.00 |
| 2016-03-17 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 20,000 | $3.86 |
| 2016-03-17 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 10,616 | $60.85 |
| 2016-03-17 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 97,484 | $60.85 |
| 2016-03-17 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 2,250 | $60.95 |
| 2016-03-17 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 20,659 | $60.95 |
| 2016-03-17 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 2,660 | $61.03 |
| 2016-03-17 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 13,936 | $61.38 |
| 2016-03-15 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 129 | $65.29 |
| 2016-03-15 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 19,642 | $67.15 |
| 2016-03-15 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 180,358 | $67.15 |
| 2016-03-15 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 19,513 | $65.80 |
| 2016-03-15 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 179,176 | $65.80 |
| 2016-03-15 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 1,182 | $65.29 |
| 2016-02-25 | WENQING, YAO | EVP, Discovery Medicinal and P | ストックオプション | 売却 | 6,566 | $0.00 |
| 2016-02-25 | WENQING, YAO | EVP, Discovery Medicinal and P | 普通株式 | 購入 | 6,566 | $18.32 |
| 2016-02-25 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 678 | $74.00 |
| 2016-02-25 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 6,022 | $74.00 |
| 2016-02-24 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 2,608 | $70.51 |
| 2016-02-24 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 914 | $71.96 |
| 2016-02-24 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 23,157 | $70.51 |
| 2016-02-24 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 2,308 | $69.70 |
| 2016-02-24 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 売却 | 1,090 | $121.95 |
| 2016-02-24 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 20,492 | $69.70 |
| 2016-02-24 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 8,111 | $71.96 |
| 2016-02-16 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 13,490 | $70.21 |
| 2016-02-16 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 43,178 | $71.10 |
| 2016-02-16 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 1,651 | $69.45 |
| 2016-02-16 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 15,187 | $69.45 |
| 2016-02-16 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 7,326 | $69.54 |
| 2016-02-16 | HUBER, REID M | EVP, Chief Scientific Officer | ストックオプション | 売却 | 5,377 | $0.00 |
| 2016-02-16 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 397,079 | $71.10 |
| 2016-02-16 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 124,057 | $70.21 |
| 2016-02-16 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 購入 | 5,377 | $18.32 |
| 2016-02-16 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 67,373 | $69.54 |
| 2016-02-16 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 897 | $70.86 |
| 2016-02-16 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 8,250 | $70.86 |
| 2016-02-14 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 購入 | 3,098 | $0.00 |
| 2016-02-12 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 16,450 | $67.94 |
| 2016-02-12 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 49,021 | $66.68 |
| 2016-02-12 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 168,055 | $64.87 |
| 2016-02-12 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 18,441 | $64.87 |
| 2016-02-12 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 541,340 | $65.80 |
| 2016-02-12 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 59,401 | $65.80 |
| 2016-02-12 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 4,183 | $63.98 |
| 2016-02-12 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 38,117 | $63.98 |
| 2016-02-12 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 149,927 | $67.94 |
| 2016-02-12 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 72,894 | $67.68 |
| 2016-02-12 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 7,999 | $67.68 |
| 2016-02-12 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 5,379 | $66.68 |
| 2016-02-11 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 761 | $60.85 |
| 2016-02-11 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 6,349 | $61.73 |
| 2016-02-11 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 136,793 | $58.13 |
| 2016-02-11 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 7,166 | $60.40 |
| 2016-02-11 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 113,546 | $61.40 |
| 2016-02-11 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 289,755 | $62.56 |
| 2016-02-11 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 19,383 | $63.37 |
| 2016-02-11 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 176,647 | $63.37 |
| 2016-02-11 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 31,795 | $62.56 |
| 2016-02-11 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 12,459 | $61.40 |
| 2016-02-11 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 65,309 | $60.40 |
| 2016-02-11 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 12,609 | $59.01 |
| 2016-02-11 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 114,908 | $59.01 |
| 2016-02-11 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 15,010 | $58.13 |
| 2016-02-11 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 25,869 | $64.46 |
| 2016-02-11 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 235,734 | $64.46 |
| 2016-02-11 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 6,939 | $60.85 |
| 2016-02-11 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 57,865 | $61.73 |
| 2016-01-15 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 13,531 | $3.11 |
| 2016-01-15 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 2,509 | $0.00 |
| 2016-01-15 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 2,509 | $18.32 |
| 2016-01-15 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 13,531 | $0.00 |
| 2016-01-15 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 13,531 | $76.96 |
| 2016-01-07 | HOPPENOT, HERVE | Director, Chairman / CEO, President | ストックオプション | 購入 | 74,094 | $0.00 |
| 2016-01-07 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 購入 | 10,442 | $0.00 |
| 2016-01-07 | HUBER, REID M | EVP, Chief Scientific Officer | ストックオプション | 購入 | 1,044 | $0.00 |
| 2016-01-07 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 1,044 | $0.00 |
| 2016-01-07 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 2,995 | $0.00 |
| 2016-01-07 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 1,108 | $0.00 |
| 2016-01-07 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 17,676 | $0.00 |
| 2016-01-07 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 2,610 | $0.00 |
| 2016-01-07 | WENQING, YAO | EVP, Discovery Medicinal and P | 普通株式 | 購入 | 2,610 | $0.00 |
| 2016-01-07 | WENQING, YAO | EVP, Discovery Medicinal and P | ストックオプション | 購入 | 18,198 | $0.00 |
| 2016-01-07 | WENQING, YAO | EVP, Discovery Medicinal and P | ストックオプション | 購入 | 586 | $0.00 |
| 2016-01-07 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 購入 | 2,995 | $0.00 |
| 2016-01-07 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 購入 | 1,044 | $0.00 |
| 2016-01-07 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 購入 | 2,610 | $0.00 |
| 2016-01-07 | HUBER, REID M | EVP, Chief Scientific Officer | ストックオプション | 購入 | 586 | $0.00 |
| 2016-01-07 | HUBER, REID M | EVP, Chief Scientific Officer | ストックオプション | 購入 | 21,170 | $0.00 |
| 2016-01-07 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 購入 | 1,108 | $0.00 |
| 2016-01-07 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 購入 | 17,676 | $0.00 |
| 2016-01-07 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 2,610 | $0.00 |
| 2016-01-07 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 購入 | 1,044 | $0.00 |
| 2016-01-07 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 購入 | 2,995 | $0.00 |
| 2016-01-07 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 購入 | 1,108 | $0.00 |
| 2016-01-07 | FLANNELLY, BARRY P | EVP & General Manager US | ストックオプション | 購入 | 17,676 | $0.00 |
| 2016-01-07 | FLANNELLY, BARRY P | EVP & General Manager US | 普通株式 | 購入 | 2,610 | $0.00 |
| 2016-01-07 | GRYSKA, DAVID W | Executive Vice President, CFO | ストックオプション | 購入 | 1,044 | $0.00 |
| 2016-01-07 | GRYSKA, DAVID W | Executive Vice President, CFO | ストックオプション | 購入 | 2,995 | $0.00 |
| 2016-01-07 | GRYSKA, DAVID W | Executive Vice President, CFO | ストックオプション | 購入 | 1,108 | $0.00 |
| 2016-01-07 | WENQING, YAO | EVP, Discovery Medicinal and P | ストックオプション | 購入 | 12,587 | $0.00 |
| 2016-01-07 | WENQING, YAO | EVP, Discovery Medicinal and P | ストックオプション | 購入 | 1,044 | $0.00 |
| 2016-01-07 | GRYSKA, DAVID W | Executive Vice President, CFO | ストックオプション | 購入 | 17,676 | $0.00 |
| 2016-01-07 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 購入 | 869 | $0.00 |
| 2016-01-07 | TROWER, PAUL | Principal Accounting Officer | 普通株式 | 購入 | 822 | $0.00 |
| 2016-01-07 | TROWER, PAUL | Principal Accounting Officer | ストックオプション | 購入 | 5,047 | $0.00 |
| 2016-01-07 | GRYSKA, DAVID W | Executive Vice President, CFO | 普通株式 | 購入 | 2,610 | $0.00 |
| 2016-01-07 | HOPPENOT, HERVE | Director, Chairman / CEO, President | ストックオプション | 購入 | 19,151 | $0.00 |
| 2016-01-07 | HOPPENOT, HERVE | Director, Chairman / CEO, President | ストックオプション | 購入 | 1,044 | $0.00 |
| 2016-01-07 | HUBER, REID M | EVP, Chief Scientific Officer | ストックオプション | 購入 | 18,198 | $0.00 |
| 2016-01-06 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | 普通株式 | 売却 | 3,937 | $101.86 |
| 2016-01-06 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | ストックオプション | 売却 | 3,937 | $0.00 |
| 2016-01-06 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | 普通株式 | 購入 | 3,937 | $18.32 |
| 2015-12-31 | HOPPENOT, HERVE | Director, Chairman / CEO, President | 普通株式 | 売却 | 32,297 | $109.11 |
| 2015-12-31 | DIXON, WENDY L | Director | 普通株式 | 購入 | 149 | $108.45 |
| 2015-12-31 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 175 | $108.45 |
| 2015-12-31 | BROOKE, PAUL A | Director | 普通株式 | 購入 | 218 | $108.45 |
| 2015-12-31 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 133 | $108.45 |
| 2015-12-10 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 売却 | 1,936 | $107.96 |
| 2015-12-10 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 1,936 | $18.32 |
| 2015-12-10 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 1,936 | $0.00 |
| 2015-12-07 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | 普通株式 | 購入 | 3,937 | $18.32 |
| 2015-12-07 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | 普通株式 | 売却 | 3,937 | $106.18 |
| 2015-12-07 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | ストックオプション | 売却 | 3,937 | $0.00 |
| 2015-11-18 | FRIEDMAN, PAUL A | Director | 普通株式 | 購入 | 125,000 | $17.79 |
| 2015-11-18 | FRIEDMAN, PAUL A | Director | 普通株式 | 売却 | 38,868 | $115.12 |
| 2015-11-18 | FRIEDMAN, PAUL A | Director | 普通株式 | 売却 | 86,132 | $115.42 |
| 2015-11-18 | FRIEDMAN, PAUL A | Director | ストックオプション | 売却 | 125,000 | $0.00 |
| 2015-11-17 | FRIEDMAN, PAUL A | Director | 普通株式 | 売却 | 7,052 | $112.71 |
| 2015-11-17 | FRIEDMAN, PAUL A | Director | ストックオプション | 売却 | 5,621 | $0.00 |
| 2015-11-17 | FRIEDMAN, PAUL A | Director | ストックオプション | 売却 | 94,379 | $0.00 |
| 2015-11-17 | FRIEDMAN, PAUL A | Director | 普通株式 | 売却 | 50,000 | $111.37 |
| 2015-11-17 | FRIEDMAN, PAUL A | Director | 普通株式 | 売却 | 42,948 | $112.53 |
| 2015-11-17 | FRIEDMAN, PAUL A | Director | 普通株式 | 購入 | 100,000 | $17.79 |
| 2015-11-10 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 売却 | 2,222 | $104.86 |
| 2015-11-10 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 1,936 | $0.00 |
| 2015-11-10 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 1,936 | $18.32 |
| 2015-11-10 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 286 | $18.32 |
| 2015-11-10 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 286 | $0.00 |
| 2015-11-06 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | ストックオプション | 売却 | 3,936 | $0.00 |
| 2015-11-06 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | 普通株式 | 購入 | 3,936 | $18.32 |
| 2015-11-06 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | 普通株式 | 売却 | 3,936 | $116.51 |
| 2015-11-03 | WENQING, YAO | EVP, Discovery Medicinal and P | 普通株式 | 購入 | 5,000 | $17.79 |
| 2015-11-03 | WENQING, YAO | EVP, Discovery Medicinal and P | 普通株式 | 売却 | 5,000 | $124.75 |
| 2015-11-03 | WENQING, YAO | EVP, Discovery Medicinal and P | 普通株式 | 売却 | 786 | $124.95 |
| 2015-11-03 | WENQING, YAO | EVP, Discovery Medicinal and P | ストックオプション | 売却 | 5,000 | $0.00 |
| 2015-10-13 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 286 | $18.32 |
| 2015-10-13 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 286 | $0.00 |
| 2015-10-13 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 売却 | 2,222 | $101.49 |
| 2015-10-13 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 1,936 | $18.32 |
| 2015-10-13 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 1,936 | $0.00 |
| 2015-10-06 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | 普通株式 | 売却 | 3,937 | $122.29 |
| 2015-10-06 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | ストックオプション | 売却 | 3,937 | $0.00 |
| 2015-10-06 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | 普通株式 | 購入 | 3,937 | $18.32 |
| 2015-10-01 | DIXON, WENDY L | Director | 普通株式 | 購入 | 147 | $110.33 |
| 2015-10-01 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 172 | $110.33 |
| 2015-10-01 | BROOKE, PAUL A | Director | 普通株式 | 購入 | 215 | $110.33 |
| 2015-10-01 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 131 | $110.33 |
| 2015-09-21 | HUBER, REID M | EVP, Chief Scientific Officer | ストックオプション | 売却 | 10,000 | $0.00 |
| 2015-09-21 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 購入 | 10,000 | $18.32 |
| 2015-09-21 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 売却 | 10,000 | $124.29 |
| 2015-09-16 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 売却 | 64,000 | $ |
| 2015-09-16 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 売却 | 2,222 | $130.69 |
| 2015-09-16 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 1,936 | $0.00 |
| 2015-09-16 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 7,292 | $ |
| 2015-09-16 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 7,406 | $ |
| 2015-09-16 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 864,614 | $ |
| 2015-09-16 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 3,642,962 | $ |
| 2015-09-16 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 101,652 | $ |
| 2015-09-16 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 売却 | 65,000 | $ |
| 2015-09-16 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 売却 | 7,587,000 | $ |
| 2015-09-16 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 売却 | 31,967,000 | $ |
| 2015-09-16 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 売却 | 892,000 | $ |
| 2015-09-16 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 1,936 | $18.32 |
| 2015-09-16 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 286 | $18.32 |
| 2015-09-16 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 286 | $0.00 |
| 2015-09-11 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | 普通株式 | 売却 | 4,301 | $130.00 |
| 2015-09-08 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | 普通株式 | 購入 | 3,937 | $18.32 |
| 2015-09-08 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | 普通株式 | 売却 | 3,937 | $118.90 |
| 2015-09-08 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | ストックオプション | 売却 | 3,937 | $0.00 |
| 2015-08-13 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 1,936 | $18.32 |
| 2015-08-13 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 286 | $0.00 |
| 2015-08-13 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 286 | $18.32 |
| 2015-08-13 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 売却 | 2,222 | $107.69 |
| 2015-08-13 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 1,936 | $0.00 |
| 2015-08-07 | HUBER, REID M | EVP, Chief Scientific Officer | ストックオプション | 売却 | 6,316 | $0.00 |
| 2015-08-07 | HUBER, REID M | EVP, Chief Scientific Officer | ストックオプション | 売却 | 2,081 | $0.00 |
| 2015-08-07 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 購入 | 2,081 | $18.32 |
| 2015-08-07 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 購入 | 6,316 | $17.79 |
| 2015-08-06 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | ストックオプション | 売却 | 3,936 | $0.00 |
| 2015-08-06 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | 普通株式 | 購入 | 3,936 | $18.32 |
| 2015-08-06 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | 普通株式 | 売却 | 3,936 | $111.95 |
| 2015-07-15 | WENQING, YAO | EVP, Discovery Medicinal and P | 普通株式 | 購入 | 5,000 | $17.79 |
| 2015-07-15 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | 普通株式 | 売却 | 70,217 | $120.00 |
| 2015-07-15 | WENQING, YAO | EVP, Discovery Medicinal and P | ストックオプション | 売却 | 5,000 | $0.00 |
| 2015-07-15 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | 普通株式 | 購入 | 70,217 | $17.79 |
| 2015-07-15 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | ストックオプション | 売却 | 70,217 | $0.00 |
| 2015-07-15 | WENQING, YAO | EVP, Discovery Medicinal and P | 普通株式 | 売却 | 5,000 | $119.75 |
| 2015-07-14 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 1,936 | $18.32 |
| 2015-07-14 | WENQING, YAO | EVP, Discovery Medicinal and P | 普通株式 | 購入 | 7,850 | $14.72 |
| 2015-07-14 | WENQING, YAO | EVP, Discovery Medicinal and P | 普通株式 | 売却 | 7,850 | $114.75 |
| 2015-07-14 | WENQING, YAO | EVP, Discovery Medicinal and P | ストックオプション | 売却 | 7,850 | $0.00 |
| 2015-07-14 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 286 | $18.32 |
| 2015-07-14 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 売却 | 2,222 | $113.61 |
| 2015-07-14 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 1,936 | $0.00 |
| 2015-07-14 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 286 | $0.00 |
| 2015-07-06 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | 普通株式 | 購入 | 3,937 | $18.32 |
| 2015-07-06 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | ストックオプション | 売却 | 3,937 | $0.00 |
| 2015-07-06 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | 普通株式 | 売却 | 3,937 | $107.00 |
| 2015-07-01 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 182 | $104.21 |
| 2015-07-01 | BROOKE, PAUL A | Director | 普通株式 | 購入 | 213 | $104.21 |
| 2015-07-01 | BIENAIME, JEAN JACQUES | Director | 普通株式 | 購入 | 127 | $104.21 |
| 2015-07-01 | DIXON, WENDY L | Director | 普通株式 | 購入 | 155 | $104.21 |
| 2015-06-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 売却 | 10,710 | $108.28 |
| 2015-06-23 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 2,778 | $0.00 |
| 2015-06-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 売却 | 981 | $107.84 |
| 2015-06-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 981 | $64.55 |
| 2015-06-23 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 7,331 | $0.00 |
| 2015-06-23 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 601 | $0.00 |
| 2015-06-23 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 981 | $0.00 |
| 2015-06-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 7,331 | $16.62 |
| 2015-06-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 2,778 | $18.32 |
| 2015-06-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 601 | $16.62 |
| 2015-06-19 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | 普通株式 | 売却 | 20,000 | $108.13 |
| 2015-06-19 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | ストックオプション | 売却 | 20,000 | $0.00 |
| 2015-06-19 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | 普通株式 | 購入 | 20,000 | $17.79 |
| 2015-06-12 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 1,936 | $18.32 |
| 2015-06-12 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 287 | $0.00 |
| 2015-06-12 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 1,936 | $0.00 |
| 2015-06-12 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 287 | $18.32 |
| 2015-06-12 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 売却 | 2,223 | $105.31 |
| 2015-06-08 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | 普通株式 | 購入 | 3,937 | $18.32 |
| 2015-06-08 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | ストックオプション | 売却 | 3,937 | $0.00 |
| 2015-06-08 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | 普通株式 | 売却 | 3,937 | $107.58 |
| 2015-05-27 | FRIEDMAN, PAUL A | Director | 普通株式 | 購入 | 69,132 | $14.72 |
| 2015-05-27 | FRIEDMAN, PAUL A | Director | ストックオプション | 売却 | 69,132 | $0.00 |
| 2015-05-27 | FRIEDMAN, PAUL A | Director | 普通株式 | 売却 | 52,696 | $107.66 |
| 2015-05-27 | FRIEDMAN, PAUL A | Director | 普通株式 | 売却 | 16,436 | $107.19 |
| 2015-05-26 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 602 | $16.62 |
| 2015-05-26 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 売却 | 11,112 | $106.43 |
| 2015-05-26 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 981 | $64.55 |
| 2015-05-26 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 売却 | 981 | $106.00 |
| 2015-05-26 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 2,778 | $0.00 |
| 2015-05-26 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 7,732 | $0.00 |
| 2015-05-26 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 602 | $0.00 |
| 2015-05-26 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 981 | $0.00 |
| 2015-05-26 | FRIEDMAN, PAUL A | Director | ストックオプション | 売却 | 127,619 | $0.00 |
| 2015-05-26 | FRIEDMAN, PAUL A | Director | 普通株式 | 購入 | 127,619 | $14.72 |
| 2015-05-26 | FRIEDMAN, PAUL A | Director | 普通株式 | 売却 | 2,619 | $107.83 |
| 2015-05-26 | FRIEDMAN, PAUL A | Director | 普通株式 | 売却 | 50,000 | $107.00 |
| 2015-05-26 | FRIEDMAN, PAUL A | Director | 普通株式 | 売却 | 2,358 | $107.36 |
| 2015-05-26 | FRIEDMAN, PAUL A | Director | 普通株式 | 売却 | 22,642 | $107.15 |
| 2015-05-26 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 2,778 | $18.32 |
| 2015-05-26 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 7,732 | $16.62 |
| 2015-05-22 | DIXON, WENDY L | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2015-05-22 | BROOKE, PAUL A | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2015-05-22 | FRIEDMAN, PAUL A | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2015-05-22 | FRIEDMAN, PAUL A | Director | 普通株式 | 購入 | 79,592 | $14.72 |
| 2015-05-22 | FRIEDMAN, PAUL A | Director | 普通株式 | 売却 | 14,392 | $108.34 |
| 2015-05-22 | FRIEDMAN, PAUL A | Director | 普通株式 | 売却 | 15,200 | $108.50 |
| 2015-05-22 | FRIEDMAN, PAUL A | Director | 普通株式 | 売却 | 25,000 | $107.75 |
| 2015-05-22 | FRIEDMAN, PAUL A | Director | 普通株式 | 売却 | 25,000 | $107.88 |
| 2015-05-22 | FRIEDMAN, PAUL A | Director | ストックオプション | 売却 | 79,592 | $0.00 |
| 2015-05-22 | BIENAIME, JEAN JACQUES | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2015-05-22 | BAKER, JULIAN | Director, 10% Owner | ストックオプション | 購入 | 15,000 | $ |
| 2015-05-22 | CLANCY, PAUL J | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2015-05-21 | FRIEDMAN, PAUL A | Director | 普通株式 | 購入 | 8,805 | $14.72 |
| 2015-05-21 | FRIEDMAN, PAUL A | Director | 普通株式 | 購入 | 13,846 | $14.72 |
| 2015-05-21 | FRIEDMAN, PAUL A | Director | 普通株式 | 売却 | 8,263 | $108.75 |
| 2015-05-21 | FRIEDMAN, PAUL A | Director | ストックオプション | 売却 | 13,846 | $0.00 |
| 2015-05-21 | FRIEDMAN, PAUL A | Director | ストックオプション | 売却 | 8,805 | $0.00 |
| 2015-05-21 | FRIEDMAN, PAUL A | Director | 普通株式 | 売却 | 14,388 | $108.92 |
| 2015-05-18 | BROOKE, PAUL A | Director | 普通株式 | 購入 | 20,000 | $7.68 |
| 2015-05-18 | BROOKE, PAUL A | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2015-05-14 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 286 | $18.32 |
| 2015-05-14 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 1,936 | $0.00 |
| 2015-05-14 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 286 | $0.00 |
| 2015-05-14 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 1,936 | $18.32 |
| 2015-05-14 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 売却 | 2,222 | $104.99 |
| 2015-05-11 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 20,000 | $7.68 |
| 2015-05-11 | BAKER, JULIAN | Director, 10% Owner | ストックオプション | 売却 | 20,000 | $ |
| 2015-05-06 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | ストックオプション | 売却 | 7,412 | $0.00 |
| 2015-05-06 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | 普通株式 | 売却 | 7,412 | $99.43 |
| 2015-05-06 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | 普通株式 | 購入 | 7,412 | $18.32 |
| 2015-04-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 1,203 | $16.62 |
| 2015-04-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 5,556 | $18.32 |
| 2015-04-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 売却 | 22,223 | $107.67 |
| 2015-04-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 15,464 | $16.62 |
| 2015-04-23 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 14,718 | $0.00 |
| 2015-04-23 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 5,556 | $0.00 |
| 2015-04-23 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 15,464 | $0.00 |
| 2015-04-23 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 1,203 | $0.00 |
| 2015-04-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 売却 | 14,718 | $107.67 |
| 2015-04-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 14,718 | $64.55 |
| 2015-04-17 | WENQING, YAO | EVP, Discovery Medicinal and P | 普通株式 | 売却 | 7,150 | $102.04 |
| 2015-04-16 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 購入 | 8,030 | $14.72 |
| 2015-04-16 | HUBER, REID M | EVP, Chief Scientific Officer | ストックオプション | 売却 | 1,355 | $0.00 |
| 2015-04-16 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 購入 | 1,355 | $13.34 |
| 2015-04-16 | HUBER, REID M | EVP, Chief Scientific Officer | ストックオプション | 売却 | 8,030 | $0.00 |
| 2015-04-16 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 購入 | 675 | $17.79 |
| 2015-04-16 | HUBER, REID M | EVP, Chief Scientific Officer | ストックオプション | 売却 | 675 | $0.00 |
| 2015-04-14 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 143 | $18.32 |
| 2015-04-14 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 968 | $0.00 |
| 2015-04-14 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 143 | $0.00 |
| 2015-04-14 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 売却 | 1,111 | $98.72 |
| 2015-04-14 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 968 | $18.32 |
| 2015-04-13 | WENQING, YAO | EVP, Discovery Medicinal and P | 普通株式 | 購入 | 14,000 | $17.79 |
| 2015-04-13 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 16,469 | $3.11 |
| 2015-04-13 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 16,469 | $0.00 |
| 2015-04-13 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 16,469 | $96.29 |
| 2015-04-13 | WENQING, YAO | EVP, Discovery Medicinal and P | ストックオプション | 売却 | 14,000 | $0.00 |
| 2015-04-13 | WENQING, YAO | EVP, Discovery Medicinal and P | 普通株式 | 売却 | 14,000 | $96.75 |
| 2015-04-10 | WENQING, YAO | EVP, Discovery Medicinal and P | 普通株式 | 購入 | 9,000 | $17.79 |
| 2015-04-10 | WENQING, YAO | EVP, Discovery Medicinal and P | 普通株式 | 売却 | 9,000 | $92.75 |
| 2015-04-10 | WENQING, YAO | EVP, Discovery Medicinal and P | ストックオプション | 売却 | 9,000 | $0.00 |
| 2015-04-07 | WENQING, YAO | EVP, Discovery Medicinal and P | 普通株式 | 売却 | 5,000 | $90.25 |
| 2015-04-07 | WENQING, YAO | EVP, Discovery Medicinal and P | 普通株式 | 購入 | 5,000 | $17.79 |
| 2015-04-07 | WENQING, YAO | EVP, Discovery Medicinal and P | ストックオプション | 売却 | 5,000 | $0.00 |
| 2015-04-07 | WENQING, YAO | EVP, Discovery Medicinal and P | 普通株式 | 売却 | 5,000 | $89.75 |
| 2015-04-07 | WENQING, YAO | EVP, Discovery Medicinal and P | 普通株式 | 売却 | 5,000 | $90.29 |
| 2015-04-07 | WENQING, YAO | EVP, Discovery Medicinal and P | 普通株式 | 売却 | 3,178 | $90.22 |
| 2015-04-07 | WENQING, YAO | EVP, Discovery Medicinal and P | 普通株式 | 売却 | 1,853 | $90.27 |
| 2015-04-06 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | ストックオプション | 売却 | 25,000 | $0.00 |
| 2015-04-06 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | 普通株式 | 売却 | 25,000 | $88.77 |
| 2015-04-06 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | 普通株式 | 購入 | 25,000 | $18.32 |
| 2015-03-30 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 購入 | 5,813 | $17.79 |
| 2015-03-30 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 売却 | 7,000 | $93.66 |
| 2015-03-30 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 購入 | 26,682 | $18.32 |
| 2015-03-30 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 売却 | 5,000 | $93.67 |
| 2015-03-30 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 売却 | 8,000 | $93.61 |
| 2015-03-30 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 売却 | 10,000 | $93.67 |
| 2015-03-30 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 購入 | 1,094 | $18.32 |
| 2015-03-30 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 購入 | 34,187 | $17.79 |
| 2015-03-30 | HUBER, REID M | EVP, Chief Scientific Officer | ストックオプション | 売却 | 16,764 | $0.00 |
| 2015-03-30 | HUBER, REID M | EVP, Chief Scientific Officer | ストックオプション | 売却 | 17,499 | $0.00 |
| 2015-03-30 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 売却 | 4,263 | $93.75 |
| 2015-03-30 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 購入 | 16,764 | $17.79 |
| 2015-03-30 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 購入 | 17,499 | $18.32 |
| 2015-03-30 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 売却 | 167 | $0.00 |
| 2015-03-30 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 売却 | 5,833 | $0.00 |
| 2015-03-30 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 売却 | 7,150 | $0.00 |
| 2015-03-30 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 売却 | 32,850 | $0.00 |
| 2015-03-30 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 売却 | 5,813 | $0.00 |
| 2015-03-30 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 売却 | 34,187 | $0.00 |
| 2015-03-30 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 売却 | 1,094 | $0.00 |
| 2015-03-30 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 購入 | 5,833 | $13.34 |
| 2015-03-30 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 売却 | 26,682 | $0.00 |
| 2015-03-30 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 購入 | 32,850 | $14.72 |
| 2015-03-30 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 購入 | 7,150 | $14.72 |
| 2015-03-30 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 購入 | 167 | $13.34 |
| 2015-03-30 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 46,000 | $93.64 |
| 2015-03-30 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 40,000 | $93.64 |
| 2015-03-30 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 27,776 | $93.64 |
| 2015-03-16 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 17,500 | $3.11 |
| 2015-03-16 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 17,500 | $89.97 |
| 2015-03-16 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 17,500 | $0.00 |
| 2015-03-12 | ARIKO, BARRY A | Director | 普通株式 | 購入 | 20,000 | $9.92 |
| 2015-03-12 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 143 | $0.00 |
| 2015-03-12 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 968 | $0.00 |
| 2015-03-12 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 売却 | 1,111 | $90.02 |
| 2015-03-12 | ARIKO, BARRY A | Director | 普通株式 | 購入 | 20,000 | $3.86 |
| 2015-03-12 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 143 | $18.32 |
| 2015-03-12 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 968 | $18.32 |
| 2015-03-12 | ARIKO, BARRY A | Director | ストックオプション | 売却 | 20,000 | $0.00 |
| 2015-03-12 | ARIKO, BARRY A | Director | 普通株式 | 売却 | 80,000 | $89.27 |
| 2015-03-12 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 売却 | 1,111 | $89.41 |
| 2015-03-12 | ARIKO, BARRY A | Director | 普通株式 | 購入 | 20,000 | $7.26 |
| 2015-03-12 | ARIKO, BARRY A | Director | 普通株式 | 購入 | 20,000 | $2.80 |
| 2015-03-10 | WENQING, YAO | EVP, Discovery Medicinal and P | 普通株式 | 購入 | 892 | $18.32 |
| 2015-03-10 | WENQING, YAO | EVP, Discovery Medicinal and P | ストックオプション | 売却 | 3,512 | $0.00 |
| 2015-03-10 | WENQING, YAO | EVP, Discovery Medicinal and P | ストックオプション | 売却 | 892 | $0.00 |
| 2015-03-10 | WENQING, YAO | EVP, Discovery Medicinal and P | 普通株式 | 購入 | 3,512 | $17.79 |
| 2015-03-06 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | ストックオプション | 売却 | 25,000 | $0.00 |
| 2015-03-06 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | 普通株式 | 売却 | 25,000 | $89.91 |
| 2015-03-06 | LEVY, RICHARD S | EVP, Chief Drug Dev Officer | 普通株式 | 購入 | 25,000 | $18.32 |
| 2015-03-05 | DE, SCHUTTER RICHARD U | Director, Chairman | 普通株式 | 購入 | 12,469 | $18.97 |
| 2015-03-05 | DE, SCHUTTER RICHARD U | Director, Chairman | 普通株式 | 売却 | 32,469 | $92.19 |
| 2015-03-05 | DE, SCHUTTER RICHARD U | Director, Chairman | 普通株式 | 購入 | 7,531 | $18.97 |
| 2015-03-05 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 売却 | 13,333 | $90.00 |
| 2015-03-05 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 13,047 | $18.32 |
| 2015-03-05 | DE, SCHUTTER RICHARD U | Director, Chairman | 普通株式 | 売却 | 7,531 | $91.68 |
| 2015-03-05 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 13,047 | $0.00 |
| 2015-03-05 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 286 | $0.00 |
| 2015-03-05 | DE, SCHUTTER RICHARD U | Director, Chairman | ストックオプション | 売却 | 20,000 | $0.00 |
| 2015-03-05 | DE, SCHUTTER RICHARD U | Director, Chairman | ストックオプション | 売却 | 7,531 | $0.00 |
| 2015-03-05 | DE, SCHUTTER RICHARD U | Director, Chairman | ストックオプション | 売却 | 12,469 | $0.00 |
| 2015-03-05 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 286 | $18.32 |
| 2015-03-05 | DE, SCHUTTER RICHARD U | Director, Chairman | 普通株式 | 購入 | 20,000 | $13.34 |
| 2015-02-25 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 売却 | 13,333 | $85.00 |
| 2015-02-25 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 286 | $0.00 |
| 2015-02-25 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 13,047 | $0.00 |
| 2015-02-25 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 13,047 | $18.32 |
| 2015-02-25 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 286 | $18.32 |
| 2015-02-24 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 売却 | 8,334 | $81.77 |
| 2015-02-24 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 7,732 | $0.00 |
| 2015-02-24 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 602 | $16.62 |
| 2015-02-24 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 7,732 | $16.62 |
| 2015-02-24 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 602 | $0.00 |
| 2015-02-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 2,778 | $18.32 |
| 2015-02-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 売却 | 2,778 | $83.44 |
| 2015-02-23 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 2,778 | $0.00 |
| 2015-02-18 | ARIKO, BARRY A | Director | 普通株式 | 売却 | 20,000 | $78.43 |
| 2015-02-18 | ARIKO, BARRY A | Director | ストックオプション | 売却 | 20,000 | $0.00 |
| 2015-02-18 | ARIKO, BARRY A | Director | 普通株式 | 購入 | 20,000 | $7.68 |
| 2015-02-17 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 購入 | 8,317 | $14.72 |
| 2015-02-17 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 購入 | 3,683 | $17.79 |
| 2015-02-17 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 売却 | 12,000 | $76.90 |
| 2015-02-17 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 売却 | 3,683 | $0.00 |
| 2015-02-17 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 17,500 | $0.00 |
| 2015-02-17 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 17,500 | $76.90 |
| 2015-02-17 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 17,500 | $3.11 |
| 2015-02-17 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 売却 | 8,317 | $0.00 |
| 2015-02-13 | HOPPENOT, HERVE | Director, Chief Executive Officer, President | 普通株式 | 売却 | 30,534 | $75.94 |
| 2015-02-13 | FRIEDMAN, PAUL A | Director | 普通株式 | 売却 | 60,000 | $74.39 |
| 2015-02-13 | FRIEDMAN, PAUL A | Director | 普通株式 | 売却 | 60,000 | $74.25 |
| 2015-02-06 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 売却 | 25,000 | $0.00 |
| 2015-02-06 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 購入 | 25,000 | $18.32 |
| 2015-02-06 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 売却 | 25,000 | $75.11 |
| 2015-01-26 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 1,042 | $17.79 |
| 2015-01-26 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 売却 | 1,042 | $80.00 |
| 2015-01-26 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 1,042 | $0.00 |
| 2015-01-23 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 150 | $17.79 |
| 2015-01-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 7,731 | $16.62 |
| 2015-01-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 601 | $16.62 |
| 2015-01-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 2,777 | $18.32 |
| 2015-01-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 売却 | 11,109 | $77.68 |
| 2015-01-23 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 601 | $0.00 |
| 2015-01-23 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 2,777 | $0.00 |
| 2015-01-23 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 売却 | 11,458 | $80.00 |
| 2015-01-23 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 11,308 | $0.00 |
| 2015-01-23 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 150 | $0.00 |
| 2015-01-23 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 7,731 | $0.00 |
| 2015-01-23 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 11,308 | $17.79 |
| 2015-01-22 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 1,042 | $0.00 |
| 2015-01-22 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 1,042 | $17.79 |
| 2015-01-22 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 売却 | 1,042 | $77.99 |
| 2015-01-20 | BIENAIME, JEAN JACQUES | Director | ストックオプション | 購入 | 25,000 | $0.00 |
| 2015-01-20 | BIENAIME, JEAN JACQUES | Director | ストックオプション | 購入 | 5,000 | $0.00 |
| 2015-01-20 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 17,500 | $3.11 |
| 2015-01-20 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 17,500 | $74.17 |
| 2015-01-20 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 17,500 | $0.00 |
| 2015-01-20 | CLANCY, PAUL J | Director | ストックオプション | 購入 | 25,000 | $0.00 |
| 2015-01-20 | CLANCY, PAUL J | Director | ストックオプション | 購入 | 5,000 | $0.00 |
| 2015-01-16 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 売却 | 12,000 | $0.00 |
| 2015-01-16 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 購入 | 12,000 | $14.72 |
| 2015-01-16 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 売却 | 12,000 | $73.07 |
| 2015-01-08 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 購入 | 3,022 | $0.00 |
| 2015-01-08 | HUBER, REID M | EVP, Chief Scientific Officer | ストックオプション | 購入 | 20,122 | $0.00 |
| 2015-01-08 | HUBER, REID M | EVP, Chief Scientific Officer | ストックオプション | 購入 | 1,423 | $0.00 |
| 2015-01-08 | HUBER, REID M | EVP, Chief Scientific Officer | ストックオプション | 購入 | 28,635 | $0.00 |
| 2015-01-08 | HUBER, REID M | EVP, Chief Scientific Officer | ストックオプション | 購入 | 1,365 | $0.00 |
| 2015-01-08 | HOPPENOT, HERVE | Director, Chief Executive Officer, President | 普通株式 | 購入 | 12,592 | $0.00 |
| 2015-01-08 | HOPPENOT, HERVE | Director, Chief Executive Officer, President | ストックオプション | 購入 | 88,406 | $0.00 |
| 2015-01-08 | HOPPENOT, HERVE | Director, Chief Executive Officer, President | ストックオプション | 購入 | 1,365 | $0.00 |
| 2015-01-08 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 151 | $17.79 |
| 2015-01-08 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 11,308 | $17.79 |
| 2015-01-08 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 4,167 | $14.00 |
| 2015-01-08 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 売却 | 15,626 | $75.00 |
| 2015-01-08 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 151 | $0.00 |
| 2015-01-08 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 11,308 | $0.00 |
| 2015-01-08 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 4,167 | $0.00 |
| 2015-01-08 | WENQING, YAO | EVP, Discovery Medicinal and P | 普通株式 | 購入 | 3,022 | $0.00 |
| 2015-01-08 | WENQING, YAO | EVP, Discovery Medicinal and P | ストックオプション | 購入 | 1,365 | $0.00 |
| 2015-01-08 | GRYSKA, DAVID W | Executive Vice President, CFO | 普通株式 | 購入 | 3,022 | $0.00 |
| 2015-01-08 | GRYSKA, DAVID W | Executive Vice President, CFO | ストックオプション | 購入 | 20,946 | $0.00 |
| 2015-01-08 | GRYSKA, DAVID W | Executive Vice President, CFO | ストックオプション | 購入 | 599 | $0.00 |
| 2015-01-08 | FLANNELLY, BARRY P | EVP, Business Development | 普通株式 | 購入 | 3,022 | $0.00 |
| 2015-01-08 | FLANNELLY, BARRY P | EVP, Business Development | ストックオプション | 購入 | 20,946 | $0.00 |
| 2015-01-08 | FLANNELLY, BARRY P | EVP, Business Development | ストックオプション | 購入 | 599 | $0.00 |
| 2015-01-08 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 3,022 | $0.00 |
| 2015-01-08 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 購入 | 20,446 | $0.00 |
| 2015-01-08 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 購入 | 1,099 | $0.00 |
| 2015-01-08 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 購入 | 1,152 | $0.00 |
| 2015-01-08 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 購入 | 6,818 | $0.00 |
| 2015-01-08 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 購入 | 1,396 | $0.00 |
| 2015-01-08 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 購入 | 4,405 | $0.00 |
| 2015-01-08 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 購入 | 1,365 | $0.00 |
| 2015-01-08 | WENQING, YAO | EVP, Discovery Medicinal and P | ストックオプション | 購入 | 19,986 | $0.00 |
| 2015-01-08 | WENQING, YAO | EVP, Discovery Medicinal and P | ストックオプション | 購入 | 1,559 | $0.00 |
| 2015-01-08 | WENQING, YAO | EVP, Discovery Medicinal and P | ストックオプション | 購入 | 18,635 | $0.00 |
| 2015-01-08 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 3,022 | $0.00 |
| 2015-01-08 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 20,189 | $0.00 |
| 2015-01-08 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 1,356 | $0.00 |
| 2015-01-08 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 3,022 | $0.00 |
| 2015-01-08 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 購入 | 20,189 | $0.00 |
| 2015-01-08 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 購入 | 1,356 | $0.00 |
| 2015-01-08 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 購入 | 3,022 | $0.00 |
| 2015-01-08 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 購入 | 20,460 | $0.00 |
| 2015-01-08 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 購入 | 1,085 | $0.00 |
| 2015-01-06 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 売却 | 25,000 | $71.84 |
| 2015-01-06 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 売却 | 25,000 | $0.00 |
| 2015-01-06 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 購入 | 25,000 | $18.32 |
| 2015-01-05 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 17,500 | $3.11 |
| 2015-01-05 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 17,500 | $73.90 |
| 2015-01-05 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 17,500 | $0.00 |
| 2014-12-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 7,833 | $16.62 |
| 2014-12-23 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 502 | $0.00 |
| 2014-12-23 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 7,833 | $0.00 |
| 2014-12-23 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 2,778 | $0.00 |
| 2014-12-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 売却 | 11,113 | $74.43 |
| 2014-12-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 502 | $16.62 |
| 2014-12-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 2,778 | $18.32 |
| 2014-12-16 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 売却 | 12,000 | $72.36 |
| 2014-12-16 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 購入 | 12,000 | $14.72 |
| 2014-12-16 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 売却 | 12,000 | $0.00 |
| 2014-12-02 | DE, SCHUTTER RICHARD U | Director, Chairman | 普通株式 | 売却 | 47,800 | $74.87 |
| 2014-12-02 | HUBER, REID M | EVP, Chief Scientific Officer | ストックオプション | 売却 | 6,494 | $0.00 |
| 2014-12-02 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 購入 | 6,494 | $9.41 |
| 2014-12-01 | DE, SCHUTTER RICHARD U | Director, Chairman | 普通株式 | 売却 | 2,200 | $75.26 |
| 2014-11-24 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 売却 | 11,111 | $74.08 |
| 2014-11-24 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 7,832 | $16.62 |
| 2014-11-24 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 7,832 | $0.00 |
| 2014-11-24 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 2,778 | $18.32 |
| 2014-11-24 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 501 | $16.62 |
| 2014-11-24 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 501 | $0.00 |
| 2014-11-24 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 2,778 | $0.00 |
| 2014-11-17 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 売却 | 12,000 | $69.97 |
| 2014-11-17 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 購入 | 12,000 | $14.72 |
| 2014-11-17 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 売却 | 12,000 | $0.00 |
| 2014-11-12 | HUBER, REID M | EVP, Chief Scientific Officer | ストックオプション | 売却 | 7,225 | $0.00 |
| 2014-11-12 | HUBER, REID M | EVP, Chief Scientific Officer | ストックオプション | 売却 | 2,900 | $0.00 |
| 2014-11-12 | HUBER, REID M | EVP, Chief Scientific Officer | ストックオプション | 売却 | 7,835 | $0.00 |
| 2014-11-12 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 購入 | 7,225 | $3.11 |
| 2014-11-12 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 購入 | 2,900 | $5.46 |
| 2014-11-12 | HUBER, REID M | EVP, Chief Scientific Officer | 普通株式 | 購入 | 7,835 | $9.41 |
| 2014-11-06 | FRIEDMAN, PAUL A | Director | 普通株式 | 購入 | 29,166 | $13.34 |
| 2014-11-06 | FRIEDMAN, PAUL A | Director | ストックオプション | 売却 | 156,487 | $0.00 |
| 2014-11-06 | FRIEDMAN, PAUL A | Director | ストックオプション | 売却 | 29,166 | $0.00 |
| 2014-11-06 | FRIEDMAN, PAUL A | Director | 普通株式 | 売却 | 185,653 | $67.87 |
| 2014-11-06 | FRIEDMAN, PAUL A | Director | 普通株式 | 購入 | 156,487 | $9.41 |
| 2014-10-31 | GRYSKA, DAVID W | Executive Vice President, CFO | ストックオプション | 購入 | 50,903 | $0.00 |
| 2014-10-31 | GRYSKA, DAVID W | Executive Vice President, CFO | 普通株式 | 購入 | 7,828 | $0.00 |
| 2014-10-31 | GRYSKA, DAVID W | Executive Vice President, CFO | ストックオプション | 購入 | 4,473 | $0.00 |
| 2014-10-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 2,778 | $18.32 |
| 2014-10-23 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 501 | $0.00 |
| 2014-10-23 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 7,832 | $0.00 |
| 2014-10-23 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 2,778 | $0.00 |
| 2014-10-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 売却 | 11,111 | $53.49 |
| 2014-10-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 501 | $16.62 |
| 2014-10-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 7,832 | $16.62 |
| 2014-10-23 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 売却 | 13,904 | $0.00 |
| 2014-10-23 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 購入 | 13,904 | $3.11 |
| 2014-10-16 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 売却 | 8,000 | $49.03 |
| 2014-10-16 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 売却 | 8,000 | $0.00 |
| 2014-10-16 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 購入 | 8,000 | $14.72 |
| 2014-09-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 7,832 | $16.62 |
| 2014-09-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 2,777 | $18.32 |
| 2014-09-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 502 | $16.62 |
| 2014-09-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 売却 | 11,111 | $47.65 |
| 2014-09-23 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 2,777 | $0.00 |
| 2014-09-23 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 7,832 | $0.00 |
| 2014-09-23 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 502 | $0.00 |
| 2014-09-16 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 売却 | 8,000 | $47.58 |
| 2014-09-16 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 購入 | 8,000 | $14.72 |
| 2014-09-16 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 売却 | 8,000 | $0.00 |
| 2014-08-25 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 2,778 | $18.32 |
| 2014-08-25 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 7,832 | $16.62 |
| 2014-08-25 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 501 | $16.62 |
| 2014-08-25 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 売却 | 11,111 | $51.96 |
| 2014-08-25 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 2,778 | $0.00 |
| 2014-08-25 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 501 | $0.00 |
| 2014-08-25 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 7,832 | $0.00 |
| 2014-08-18 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 売却 | 8,000 | $0.00 |
| 2014-08-18 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 売却 | 8,000 | $51.97 |
| 2014-08-18 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 購入 | 8,000 | $14.72 |
| 2014-08-11 | FLANNELLY, BARRY P | See Remarks | ストックオプション | 購入 | 6,192 | $0.00 |
| 2014-08-11 | FLANNELLY, BARRY P | See Remarks | ストックオプション | 購入 | 42,218 | $0.00 |
| 2014-07-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 2,778 | $18.32 |
| 2014-07-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 7,832 | $16.62 |
| 2014-07-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 売却 | 11,111 | $48.54 |
| 2014-07-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 501 | $16.62 |
| 2014-07-23 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 501 | $0.00 |
| 2014-07-23 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 7,832 | $0.00 |
| 2014-07-23 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 2,778 | $0.00 |
| 2014-07-16 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 売却 | 8,000 | $0.00 |
| 2014-07-16 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 売却 | 8,000 | $48.15 |
| 2014-07-16 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 購入 | 8,000 | $14.72 |
| 2014-06-23 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 2,777 | $0.00 |
| 2014-06-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 売却 | 8,334 | $55.92 |
| 2014-06-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 502 | $16.62 |
| 2014-06-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 7,832 | $16.62 |
| 2014-06-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 売却 | 2,777 | $56.38 |
| 2014-06-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 2,777 | $18.32 |
| 2014-06-23 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 7,832 | $0.00 |
| 2014-06-23 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 502 | $0.00 |
| 2014-06-16 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 購入 | 8,000 | $14.72 |
| 2014-06-16 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 売却 | 8,000 | $0.00 |
| 2014-06-16 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 売却 | 8,000 | $53.88 |
| 2014-06-05 | HASTINGS, DAVID C | Chief Financial Officer | 普通株式 | 購入 | 50,000 | $5.46 |
| 2014-06-05 | HASTINGS, DAVID C | Chief Financial Officer | 普通株式 | 購入 | 23,966 | $9.41 |
| 2014-06-05 | HASTINGS, DAVID C | Chief Financial Officer | 普通株式 | 購入 | 50,000 | $3.11 |
| 2014-06-05 | HASTINGS, DAVID C | Chief Financial Officer | 普通株式 | 売却 | 123,966 | $52.81 |
| 2014-06-05 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 売却 | 23,966 | $0.00 |
| 2014-06-05 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 売却 | 50,000 | $0.00 |
| 2014-06-04 | HASTINGS, DAVID C | Chief Financial Officer | 普通株式 | 購入 | 43,500 | $14.72 |
| 2014-06-04 | HASTINGS, DAVID C | Chief Financial Officer | 普通株式 | 売却 | 76,034 | $52.61 |
| 2014-06-04 | HASTINGS, DAVID C | Chief Financial Officer | 普通株式 | 購入 | 6,500 | $17.79 |
| 2014-06-04 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 売却 | 7,500 | $0.00 |
| 2014-06-04 | HASTINGS, DAVID C | Chief Financial Officer | 普通株式 | 購入 | 18,534 | $9.41 |
| 2014-06-04 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 売却 | 6,500 | $0.00 |
| 2014-06-04 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 売却 | 18,534 | $0.00 |
| 2014-06-04 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 売却 | 43,500 | $0.00 |
| 2014-06-04 | HASTINGS, DAVID C | Chief Financial Officer | 普通株式 | 購入 | 7,500 | $13.34 |
| 2014-05-28 | ARIKO, BARRY A | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2014-05-28 | DE, SCHUTTER RICHARD U | Director, Chairman | ストックオプション | 購入 | 15,000 | $0.00 |
| 2014-05-28 | BAKER, JULIAN | Director, 10% Owner | ストックオプション | 購入 | 15,000 | $ |
| 2014-05-28 | DIXON, WENDY L | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2014-05-28 | FRIEDMAN, PAUL A | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2014-05-28 | BROOKE, PAUL A | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2014-05-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 7,832 | $16.62 |
| 2014-05-23 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 7,832 | $0.00 |
| 2014-05-23 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 501 | $0.00 |
| 2014-05-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 2,778 | $18.32 |
| 2014-05-23 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 2,778 | $0.00 |
| 2014-05-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 売却 | 11,111 | $48.48 |
| 2014-05-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 501 | $16.62 |
| 2014-05-21 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 10,000 | $7.02 |
| 2014-05-21 | BAKER, JULIAN | Director, 10% Owner | ストックオプション | 売却 | 10,000 | $ |
| 2014-05-16 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 売却 | 8,000 | $50.68 |
| 2014-05-16 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 購入 | 8,000 | $14.72 |
| 2014-05-16 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 売却 | 8,000 | $0.00 |
| 2014-05-12 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 2,058 | $54.00 |
| 2014-05-02 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 購入 | 14,594 | $9.41 |
| 2014-05-02 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 34,000 | $51.55 |
| 2014-05-02 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 購入 | 19,406 | $9.41 |
| 2014-05-02 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 売却 | 19,406 | $0.00 |
| 2014-05-02 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 売却 | 14,594 | $0.00 |
| 2014-04-28 | BROOKE, PAUL A | Director | ストックオプション | 売却 | 25,000 | $0.00 |
| 2014-04-28 | BROOKE, PAUL A | Director | 普通株式 | 購入 | 25,000 | $7.02 |
| 2014-04-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 1,504 | $16.62 |
| 2014-04-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 売却 | 30,555 | $47.71 |
| 2014-04-23 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 5,555 | $0.00 |
| 2014-04-23 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 23,496 | $0.00 |
| 2014-04-23 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 1,504 | $0.00 |
| 2014-04-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 5,555 | $18.32 |
| 2014-04-23 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 23,496 | $16.62 |
| 2014-02-20 | FRIEDMAN, PAUL A | Director | 普通株式 | 売却 | 33,354 | $63.51 |
| 2014-02-20 | FRIEDMAN, PAUL A | Director | 普通株式 | 購入 | 33,354 | $3.11 |
| 2014-02-20 | FRIEDMAN, PAUL A | Director | ストックオプション | 売却 | 33,354 | $0.00 |
| 2014-02-19 | DE, SCHUTTER RICHARD U | Director, Chairman | 普通株式 | 売却 | 7,455 | $65.50 |
| 2014-02-19 | FRIEDMAN, PAUL A | Director | 普通株式 | 購入 | 40,919 | $3.11 |
| 2014-02-19 | DE, SCHUTTER RICHARD U | Director, Chairman | 普通株式 | 購入 | 7,455 | $8.88 |
| 2014-02-19 | FRIEDMAN, PAUL A | Director | 普通株式 | 売却 | 40,919 | $62.66 |
| 2014-02-19 | FRIEDMAN, PAUL A | Director | ストックオプション | 売却 | 40,919 | $0.00 |
| 2014-02-19 | DE, SCHUTTER RICHARD U | Director, Chairman | ストックオプション | 売却 | 7,455 | $0.00 |
| 2014-02-18 | FRIEDMAN, PAUL A | Director | 普通株式 | 売却 | 720,036 | $65.82 |
| 2014-02-18 | DE, SCHUTTER RICHARD U | Director, Chairman | ストックオプション | 売却 | 42,545 | $0.00 |
| 2014-02-18 | FRIEDMAN, PAUL A | Director | 普通株式 | 購入 | 39,166 | $8.99 |
| 2014-02-18 | FRIEDMAN, PAUL A | Director | ストックオプション | 売却 | 181,426 | $0.00 |
| 2014-02-18 | FRIEDMAN, PAUL A | Director | ストックオプション | 売却 | 39,166 | $0.00 |
| 2014-02-18 | FRIEDMAN, PAUL A | Director | 普通株式 | 購入 | 181,426 | $11.98 |
| 2014-02-18 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 売却 | 32,001 | $0.00 |
| 2014-02-18 | FRIEDMAN, PAUL A | Director | 普通株式 | 購入 | 185,753 | $5.46 |
| 2014-02-18 | FRIEDMAN, PAUL A | Director | 普通株式 | 購入 | 193,520 | $8.99 |
| 2014-02-18 | HASTINGS, DAVID C | Chief Financial Officer | 普通株式 | 購入 | 32,001 | $8.99 |
| 2014-02-18 | HASTINGS, DAVID C | Chief Financial Officer | 普通株式 | 売却 | 32,001 | $65.64 |
| 2014-02-18 | FRIEDMAN, PAUL A | Director | ストックオプション | 売却 | 185,753 | $0.00 |
| 2014-02-18 | FRIEDMAN, PAUL A | Director | ストックオプション | 売却 | 193,520 | $0.00 |
| 2014-02-18 | FRIEDMAN, PAUL A | Director | ストックオプション | 売却 | 120,171 | $0.00 |
| 2014-02-18 | DE, SCHUTTER RICHARD U | Director, Chairman | 普通株式 | 購入 | 42,545 | $8.88 |
| 2014-02-18 | DE, SCHUTTER RICHARD U | Director, Chairman | 普通株式 | 売却 | 42,545 | $65.54 |
| 2014-02-18 | FRIEDMAN, PAUL A | Director | 普通株式 | 購入 | 120,171 | $3.11 |
| 2014-02-14 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 売却 | 34,964 | $0.00 |
| 2014-02-14 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 売却 | 14,583 | $0.00 |
| 2014-02-14 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 売却 | 24,787 | $0.00 |
| 2014-02-14 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 売却 | 39,787 | $66.13 |
| 2014-02-14 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 売却 | 417 | $0.00 |
| 2014-02-14 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 購入 | 417 | $13.34 |
| 2014-02-14 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 購入 | 14,583 | $13.34 |
| 2014-02-14 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 購入 | 24,787 | $9.41 |
| 2014-02-14 | FRIEDMAN, PAUL A | Director | 普通株式 | 売却 | 10,227 | $65.52 |
| 2014-02-14 | FRIEDMAN, PAUL A | Director | ストックオプション | 売却 | 10,227 | $0.00 |
| 2014-02-14 | FRIEDMAN, PAUL A | Director | 普通株式 | 購入 | 10,227 | $11.98 |
| 2014-02-14 | HASTINGS, DAVID C | Chief Financial Officer | 普通株式 | 購入 | 34,964 | $8.99 |
| 2014-02-14 | HASTINGS, DAVID C | Chief Financial Officer | 普通株式 | 購入 | 5,036 | $8.99 |
| 2014-02-14 | HASTINGS, DAVID C | Chief Financial Officer | 普通株式 | 売却 | 40,000 | $64.74 |
| 2014-02-14 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 売却 | 5,036 | $0.00 |
| 2014-02-13 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 売却 | 3,334 | $0.00 |
| 2014-02-13 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 売却 | 158,331 | $66.49 |
| 2014-02-13 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 33,333 | $0.00 |
| 2014-02-13 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 6,517 | $0.00 |
| 2014-02-13 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 購入 | 9,138 | $11.98 |
| 2014-02-13 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 購入 | 12,300 | $9.41 |
| 2014-02-13 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 売却 | 90,335 | $0.00 |
| 2014-02-13 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 売却 | 13,000 | $0.00 |
| 2014-02-13 | HASTINGS, DAVID C | Chief Financial Officer | 普通株式 | 売却 | 202,999 | $66.12 |
| 2014-02-13 | HASTINGS, DAVID C | Chief Financial Officer | 普通株式 | 購入 | 66,000 | $17.79 |
| 2014-02-13 | HASTINGS, DAVID C | Chief Financial Officer | 普通株式 | 購入 | 90,335 | $11.98 |
| 2014-02-13 | HASTINGS, DAVID C | Chief Financial Officer | 普通株式 | 購入 | 16,000 | $18.32 |
| 2014-02-13 | HASTINGS, DAVID C | Chief Financial Officer | 普通株式 | 購入 | 13,000 | $14.72 |
| 2014-02-13 | HASTINGS, DAVID C | Chief Financial Officer | 普通株式 | 購入 | 9,665 | $11.98 |
| 2014-02-13 | HASTINGS, DAVID C | Chief Financial Officer | 普通株式 | 購入 | 7,999 | $8.99 |
| 2014-02-13 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 売却 | 11,112 | $0.00 |
| 2014-02-13 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 売却 | 31,126 | $0.00 |
| 2014-02-13 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 売却 | 8,874 | $0.00 |
| 2014-02-13 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 売却 | 14,477 | $0.00 |
| 2014-02-13 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 売却 | 3,888 | $0.00 |
| 2014-02-13 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 売却 | 25,523 | $0.00 |
| 2014-02-13 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 売却 | 191,309 | $66.38 |
| 2014-02-13 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 98,334 | $66.28 |
| 2014-02-13 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 購入 | 11,112 | $3.11 |
| 2014-02-13 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 購入 | 31,126 | $11.98 |
| 2014-02-13 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 購入 | 3,888 | $3.11 |
| 2014-02-13 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 購入 | 25,523 | $8.99 |
| 2014-02-13 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 26,667 | $0.00 |
| 2014-02-13 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 4,802 | $0.00 |
| 2014-02-13 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 10,390 | $0.00 |
| 2014-02-13 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 118,481 | $16.62 |
| 2014-02-13 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 6,517 | $16.62 |
| 2014-02-13 | DALY, JAMES M | EVP, Chief Commercial Officer | 普通株式 | 購入 | 33,333 | $18.32 |
| 2014-02-13 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 売却 | 1,945 | $0.00 |
| 2014-02-13 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 売却 | 9,138 | $0.00 |
| 2014-02-13 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 購入 | 25,862 | $11.98 |
| 2014-02-13 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 購入 | 47,913 | $9.41 |
| 2014-02-13 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 売却 | 33,055 | $0.00 |
| 2014-02-13 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 売却 | 61,096 | $0.00 |
| 2014-02-13 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 売却 | 47,913 | $0.00 |
| 2014-02-13 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 売却 | 25,862 | $0.00 |
| 2014-02-13 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 売却 | 12,300 | $0.00 |
| 2014-02-13 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 売却 | 9,665 | $0.00 |
| 2014-02-13 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 購入 | 61,096 | $3.11 |
| 2014-02-13 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 購入 | 33,055 | $11.98 |
| 2014-02-13 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 売却 | 66,000 | $0.00 |
| 2014-02-13 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 売却 | 16,000 | $0.00 |
| 2014-02-13 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 売却 | 7,999 | $0.00 |
| 2014-02-13 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 購入 | 8,874 | $11.98 |
| 2014-02-13 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 購入 | 3,334 | $6.95 |
| 2014-02-13 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 購入 | 14,477 | $8.99 |
| 2014-02-13 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 4,802 | $16.66 |
| 2014-02-13 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 10,390 | $17.79 |
| 2014-02-13 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 1,389 | $14.00 |
| 2014-02-13 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 417 | $13.34 |
| 2014-02-13 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 9,665 | $11.98 |
| 2014-02-13 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 16,967 | $5.46 |
| 2014-02-13 | ARIKO, BARRY A | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2014-02-13 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 1,389 | $0.00 |
| 2014-02-13 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 1,112 | $0.00 |
| 2014-02-13 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 売却 | 118,481 | $0.00 |
| 2014-02-13 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 2,778 | $0.00 |
| 2014-02-13 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 4,445 | $0.00 |
| 2014-02-13 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 3,245 | $0.00 |
| 2014-02-13 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 27 | $0.00 |
| 2014-02-13 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 売却 | 1,187 | $66.50 |
| 2014-02-13 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 売却 | 54,855 | $66.67 |
| 2014-02-13 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 26,667 | $18.32 |
| 2014-02-13 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 1,112 | $14.72 |
| 2014-02-13 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 2,778 | $14.00 |
| 2014-02-13 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 4,445 | $14.72 |
| 2014-02-13 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 3,245 | $16.66 |
| 2014-02-13 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 27 | $17.79 |
| 2014-02-13 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 417 | $0.00 |
| 2014-02-13 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 12,070 | $0.00 |
| 2014-02-13 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 14,583 | $0.00 |
| 2014-02-13 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 72,930 | $0.00 |
| 2014-02-13 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 90,335 | $0.00 |
| 2014-02-13 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 9,665 | $0.00 |
| 2014-02-13 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 16,967 | $0.00 |
| 2014-02-13 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 216,967 | $66.73 |
| 2014-02-13 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 14,583 | $13.34 |
| 2014-02-13 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 12,070 | $9.41 |
| 2014-02-13 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 72,930 | $9.41 |
| 2014-02-13 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 90,335 | $11.98 |
| 2014-02-13 | ARIKO, BARRY A | Director | 普通株式 | 購入 | 10,000 | $7.02 |
| 2014-02-13 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 購入 | 1,945 | $11.98 |
| 2014-02-13 | ARIKO, BARRY A | Director | 普通株式 | 売却 | 10,000 | $66.49 |
| 2014-01-21 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 24,139 | $0.00 |
| 2014-01-21 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 購入 | 1,135 | $0.00 |
| 2014-01-21 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 購入 | 1,143 | $0.00 |
| 2014-01-21 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 購入 | 6,943 | $0.00 |
| 2014-01-21 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 購入 | 977 | $0.00 |
| 2014-01-21 | HOPPENOT, HERVE | Director, Chief Executive Officer, President | ストックオプション | 購入 | 119,501 | $0.00 |
| 2014-01-21 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 購入 | 1,450 | $0.00 |
| 2014-01-21 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 購入 | 23,852 | $0.00 |
| 2014-01-21 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 購入 | 23,379 | $0.00 |
| 2014-01-21 | FRIEDMAN, PAUL A | Director | ストックオプション | 購入 | 7,500 | $0.00 |
| 2014-01-21 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 購入 | 982 | $0.00 |
| 2014-01-21 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 購入 | 34,342 | $0.00 |
| 2014-01-21 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 690 | $0.00 |
| 2014-01-21 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 購入 | 997 | $0.00 |
| 2014-01-21 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 購入 | 34,868 | $0.00 |
| 2014-01-21 | HOPPENOT, HERVE | Director, Chief Executive Officer, President | ストックオプション | 購入 | 4,647 | $0.00 |
| 2014-01-13 | HOPPENOT, HERVE | Director, President and CEO | 普通株式 | 購入 | 400,000 | $0.00 |
| 2013-12-20 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 普通株式 | 売却 | 24,350 | $50.11 |
| 2013-12-17 | WHITFIELD, ROY A | Director | 普通株式 | 購入 | 15,000 | $7.68 |
| 2013-12-17 | WHITFIELD, ROY A | Director | 普通株式 | 購入 | 10,000 | $7.02 |
| 2013-12-17 | WHITFIELD, ROY A | Director | ストックオプション | 売却 | 15,000 | $0.00 |
| 2013-12-17 | WHITFIELD, ROY A | Director | ストックオプション | 売却 | 20,000 | $0.00 |
| 2013-12-17 | WHITFIELD, ROY A | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2013-12-17 | WHITFIELD, ROY A | Director | 普通株式 | 購入 | 20,000 | $7.26 |
| 2013-11-18 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 50,000 | $47.37 |
| 2013-11-08 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 219,544,000 | $100.00 |
| 2013-11-08 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 3,415,000 | $104.13 |
| 2013-11-08 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 85,000 | $104.13 |
| 2013-11-08 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 5,367,000 | $104.09 |
| 2013-11-08 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 219,544,000 | $100.00 |
| 2013-11-08 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 242,000 | $104.25 |
| 2013-11-08 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 6,830,000 | $104.52 |
| 2013-11-08 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 170,000 | $104.52 |
| 2013-11-08 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 売却 | 20,922,000 | $425.88 |
| 2013-11-08 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 売却 | 88,153,000 | $425.88 |
| 2013-11-08 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 売却 | 2,459,000 | $425.88 |
| 2013-11-08 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 9,758,000 | $104.25 |
| 2013-11-08 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 61,000 | $103.75 |
| 2013-11-08 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 121,000 | $104.75 |
| 2013-11-08 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 4,879,000 | $104.75 |
| 2013-11-08 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 5,456,000 | $100.00 |
| 2013-11-08 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 25,000,000 | $100.00 |
| 2013-11-08 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 133,000 | $104.09 |
| 2013-11-08 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 2,439,000 | $103.75 |
| 2013-11-08 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 売却 | 127,000 | $432.60 |
| 2013-11-08 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 売却 | 4,567,000 | $432.60 |
| 2013-11-08 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 売却 | 1,084,000 | $432.60 |
| 2013-11-08 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 25,000,000 | $100.00 |
| 2013-11-08 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 5,456,000 | $100.00 |
| 2013-09-10 | FRIEDMAN, PAUL A | Chief Executive Officer | ストックオプション | 売却 | 189,105 | $0.00 |
| 2013-09-10 | FRIEDMAN, PAUL A | Chief Executive Officer | 普通株式 | 購入 | 144,559 | $8.64 |
| 2013-09-10 | FRIEDMAN, PAUL A | Chief Executive Officer | 普通株式 | 購入 | 43,125 | $8.64 |
| 2013-09-10 | FRIEDMAN, PAUL A | Chief Executive Officer | 普通株式 | 購入 | 189,105 | $7.09 |
| 2013-09-10 | FRIEDMAN, PAUL A | Chief Executive Officer | 普通株式 | 売却 | 376,789 | $37.32 |
| 2013-09-10 | FRIEDMAN, PAUL A | Chief Executive Officer | ストックオプション | 売却 | 144,559 | $0.00 |
| 2013-09-10 | FRIEDMAN, PAUL A | Chief Executive Officer | ストックオプション | 売却 | 43,125 | $0.00 |
| 2013-09-09 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 36,067 | $37.90 |
| 2013-09-06 | HASTINGS, DAVID C | Chief Financial Officer | 普通株式 | 売却 | 100,000 | $35.16 |
| 2013-09-06 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 売却 | 94,444 | $0.00 |
| 2013-09-06 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 35,413 | $0.00 |
| 2013-09-06 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 売却 | 55,978 | $35.17 |
| 2013-09-06 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 4,167 | $0.00 |
| 2013-09-06 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 9,732 | $0.00 |
| 2013-09-06 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 売却 | 5,556 | $0.00 |
| 2013-09-06 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 9,732 | $16.66 |
| 2013-09-06 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 6,666 | $14.72 |
| 2013-09-06 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 6,666 | $0.00 |
| 2013-09-06 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 4,167 | $14.00 |
| 2013-09-06 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 35,413 | $17.79 |
| 2013-09-06 | HASTINGS, DAVID C | Chief Financial Officer | 普通株式 | 購入 | 94,444 | $7.09 |
| 2013-09-06 | HASTINGS, DAVID C | Chief Financial Officer | 普通株式 | 購入 | 5,556 | $7.09 |
| 2013-09-06 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 売却 | 25,000 | $0.00 |
| 2013-09-06 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 購入 | 25,000 | $11.98 |
| 2013-09-06 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 売却 | 25,000 | $35.28 |
| 2013-09-05 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 8,767 | $34.90 |
| 2013-09-05 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 94,444 | $35.06 |
| 2013-09-05 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 94,444 | $7.09 |
| 2013-09-05 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 売却 | 5,733 | $0.00 |
| 2013-09-05 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 売却 | 4,300 | $0.00 |
| 2013-09-05 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 購入 | 31,767 | $8.73 |
| 2013-09-05 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 購入 | 4,300 | $7.09 |
| 2013-09-05 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 購入 | 5,733 | $8.73 |
| 2013-09-05 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 売却 | 31,767 | $0.00 |
| 2013-09-05 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 94,444 | $0.00 |
| 2013-08-19 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 50,000 | $26.70 |
| 2013-06-11 | BAKER, JULIAN | Director, 10% Owner | ストックオプション | 売却 | 10,000 | $4.44 |
| 2013-06-11 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 10,000 | $4.44 |
| 2013-05-30 | ARIKO, BARRY A | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2013-05-30 | DE, SCHUTTER RICHARD U | Director, Chairman | ストックオプション | 購入 | 20,000 | $0.00 |
| 2013-05-30 | BROOKE, PAUL A | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2013-05-30 | BAKER, JULIAN | Director, 10% Owner | ストックオプション | 購入 | 20,000 | $0.00 |
| 2013-05-30 | WHITFIELD, ROY A | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2013-05-30 | DIXON, WENDY L | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2013-05-17 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 40,000 | $23.08 |
| 2013-05-13 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 売却 | 55,699 | $22.30 |
| 2013-05-13 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 購入 | 4,301 | $7.09 |
| 2013-05-13 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 購入 | 55,699 | $7.09 |
| 2013-05-13 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 売却 | 55,699 | $0.00 |
| 2013-05-13 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 売却 | 4,301 | $0.00 |
| 2013-05-06 | FRIEDMAN, PAUL A | Chief Executive Officer | 普通株式 | 購入 | 8,347 | $11.98 |
| 2013-05-06 | FRIEDMAN, PAUL A | Chief Executive Officer | 普通株式 | 購入 | 13,513 | $9.41 |
| 2013-05-06 | FRIEDMAN, PAUL A | Chief Executive Officer | 普通株式 | 購入 | 834 | $13.34 |
| 2013-05-06 | FRIEDMAN, PAUL A | Chief Executive Officer | 普通株式 | 購入 | 1,006 | $14.72 |
| 2013-05-06 | FRIEDMAN, PAUL A | Chief Executive Officer | ストックオプション | 売却 | 8,347 | $0.00 |
| 2013-05-06 | FRIEDMAN, PAUL A | Chief Executive Officer | ストックオプション | 売却 | 1,006 | $0.00 |
| 2013-05-06 | FRIEDMAN, PAUL A | Chief Executive Officer | ストックオプション | 売却 | 834 | $0.00 |
| 2013-05-06 | FRIEDMAN, PAUL A | Chief Executive Officer | ストックオプション | 売却 | 13,513 | $0.00 |
| 2013-04-05 | ARIKO, BARRY A | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2013-04-05 | ARIKO, BARRY A | Director | 普通株式 | 購入 | 10,000 | $4.44 |
| 2013-03-14 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 10,000 | $25.08 |
| 2013-03-01 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 10,000 | $22.56 |
| 2013-02-28 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 11,110 | $14.72 |
| 2013-02-28 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 4,169 | $17.79 |
| 2013-02-28 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 17,020 | $16.66 |
| 2013-02-28 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 5,202 | $16.66 |
| 2013-02-28 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 4,169 | $0.00 |
| 2013-02-28 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 12,499 | $0.00 |
| 2013-02-28 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 11,110 | $0.00 |
| 2013-02-28 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 17,020 | $0.00 |
| 2013-02-28 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 5,202 | $0.00 |
| 2013-02-28 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 売却 | 50,000 | $22.16 |
| 2013-02-28 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 12,499 | $14.00 |
| 2013-02-27 | BROOKE, PAUL A | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2013-02-27 | BROOKE, PAUL A | Director | 普通株式 | 購入 | 10,000 | $4.44 |
| 2013-02-20 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 83,033 | $5.46 |
| 2013-02-20 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 83,033 | $0.00 |
| 2013-02-20 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 20,250 | $0.00 |
| 2013-02-20 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 20,250 | $8.19 |
| 2013-02-20 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 103,283 | $21.53 |
| 2013-02-19 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 30,000 | $21.82 |
| 2013-02-15 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 売却 | 38,440 | $0.00 |
| 2013-02-15 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 売却 | 43,749 | $0.00 |
| 2013-02-15 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 売却 | 98,440 | $22.48 |
| 2013-02-15 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 購入 | 38,440 | $8.99 |
| 2013-02-15 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 購入 | 16,251 | $5.46 |
| 2013-02-15 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 購入 | 43,749 | $5.46 |
| 2013-02-15 | HASTINGS, DAVID C | Chief Financial Officer | 普通株式 | 購入 | 60,000 | $5.12 |
| 2013-02-15 | HASTINGS, DAVID C | Chief Financial Officer | 普通株式 | 売却 | 100,000 | $22.52 |
| 2013-02-15 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 売却 | 9,583 | $0.00 |
| 2013-02-15 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 売却 | 417 | $0.00 |
| 2013-02-15 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 売却 | 30,000 | $0.00 |
| 2013-02-15 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 売却 | 60,000 | $0.00 |
| 2013-02-15 | HASTINGS, DAVID C | Chief Financial Officer | 普通株式 | 購入 | 30,000 | $8.99 |
| 2013-02-15 | HASTINGS, DAVID C | Chief Financial Officer | 普通株式 | 購入 | 417 | $8.19 |
| 2013-02-15 | HASTINGS, DAVID C | Chief Financial Officer | 普通株式 | 購入 | 9,583 | $8.19 |
| 2013-02-15 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 売却 | 16,251 | $0.00 |
| 2013-02-09 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 購入 | 7,879 | $0.00 |
| 2013-02-09 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 購入 | 6,601 | $0.00 |
| 2013-02-09 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 購入 | 33,399 | $0.00 |
| 2013-02-09 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 購入 | 5,458 | $0.00 |
| 2013-02-09 | DALY, JAMES M | EVP, Chief Commercial Officer | ストックオプション | 購入 | 94,542 | $0.00 |
| 2013-02-09 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | ストックオプション | 購入 | 5,458 | $0.00 |
| 2013-02-09 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | ストックオプション | 購入 | 194,542 | $0.00 |
| 2013-02-09 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 購入 | 5,538 | $0.00 |
| 2013-02-09 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 購入 | 44,462 | $0.00 |
| 2013-02-09 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 8,218 | $0.00 |
| 2013-02-09 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 91,782 | $0.00 |
| 2013-02-09 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 購入 | 8,218 | $0.00 |
| 2013-02-09 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 購入 | 141,782 | $0.00 |
| 2013-02-09 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 購入 | 72,121 | $0.00 |
| 2012-12-20 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 普通株式 | 売却 | 16,725 | $16.15 |
| 2012-12-17 | DE, SCHUTTER RICHARD U | Director, Chairman | 普通株式 | 売却 | 50,000 | $16.03 |
| 2012-12-17 | DE, SCHUTTER RICHARD U | Director, Chairman | 普通株式 | 購入 | 45,000 | $16.11 |
| 2012-10-22 | DALY, JAMES M | Exec. VP & Chief Comm. Officer | ストックオプション | 購入 | 281,952 | $0.00 |
| 2012-10-22 | DALY, JAMES M | Exec. VP & Chief Comm. Officer | ストックオプション | 購入 | 18,048 | $0.00 |
| 2012-08-01 | BAKER, JULIAN | Director, 10% Owner | ストックオプション | 売却 | 10,000 | $5.67 |
| 2012-08-01 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 10,000 | $5.67 |
| 2012-07-12 | ARIKO, BARRY A | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2012-07-12 | ARIKO, BARRY A | Director | 普通株式 | 購入 | 10,000 | $5.67 |
| 2012-07-10 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 普通株式 | 購入 | 6,480 | $8.99 |
| 2012-07-10 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 普通株式 | 購入 | 5,556 | $3.11 |
| 2012-07-10 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | ストックオプション | 売却 | 834 | $0.00 |
| 2012-07-10 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | ストックオプション | 売却 | 1,875 | $0.00 |
| 2012-07-10 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | ストックオプション | 売却 | 10,441 | $0.00 |
| 2012-07-10 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | ストックオプション | 売却 | 6,480 | $0.00 |
| 2012-07-10 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | ストックオプション | 売却 | 5,556 | $0.00 |
| 2012-07-10 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 普通株式 | 購入 | 1,875 | $8.64 |
| 2012-07-10 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 普通株式 | 購入 | 10,441 | $8.64 |
| 2012-07-10 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 普通株式 | 購入 | 834 | $8.99 |
| 2012-07-05 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 購入 | 35,700 | $7.09 |
| 2012-07-05 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 5,586 | $25.10 |
| 2012-07-05 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 27,300 | $25.11 |
| 2012-07-05 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 2,214 | $25.12 |
| 2012-07-05 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 600 | $25.13 |
| 2012-07-05 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 売却 | 35,700 | $0.00 |
| 2012-07-02 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 36,666 | $24.15 |
| 2012-07-02 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 購入 | 36,666 | $6.95 |
| 2012-07-02 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 売却 | 36,666 | $0.00 |
| 2012-06-04 | BAKER, JULIAN | Director, 10% Owner | 普通株式 | 購入 | 5,000 | $6.66 |
| 2012-06-04 | BAKER, JULIAN | Director, 10% Owner | ストックオプション | 売却 | 5,000 | $6.66 |
| 2012-05-30 | BAKER, JULIAN | Director, 10% Owner | ストックオプション | 購入 | 20,000 | $0.00 |
| 2012-05-30 | BROOKE, PAUL A | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2012-05-30 | ARIKO, BARRY A | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2012-05-30 | DIXON, WENDY L | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2012-05-30 | WHITFIELD, ROY A | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2012-05-30 | DE, SCHUTTER RICHARD U | Director, Chairman | ストックオプション | 購入 | 20,000 | $0.00 |
| 2012-05-24 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 20,000 | $22.27 |
| 2012-05-23 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 2,000 | $0.00 |
| 2012-05-17 | ARIKO, BARRY A | Director | ストックオプション | 売却 | 5,000 | $0.00 |
| 2012-05-17 | ARIKO, BARRY A | Director | 普通株式 | 購入 | 5,000 | $6.66 |
| 2012-05-16 | BROOKE, PAUL A | Director | 普通株式 | 購入 | 5,000 | $6.66 |
| 2012-05-16 | BROOKE, PAUL A | Director | ストックオプション | 売却 | 5,000 | $0.00 |
| 2012-05-16 | BROOKE, PAUL A | Director | 普通株式 | 売却 | 5,000 | $23.55 |
| 2012-05-14 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 売却 | 56,666 | $23.12 |
| 2012-05-14 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 8,002 | $16.66 |
| 2012-05-14 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 31,997 | $16.66 |
| 2012-05-14 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 購入 | 16,667 | $14.72 |
| 2012-05-14 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 売却 | 100 | $23.12 |
| 2012-05-14 | SIEGEL, ERIC H. | EVP, General Counsel | 普通株式 | 売却 | 715 | $23.11 |
| 2012-05-14 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 8,002 | $0.00 |
| 2012-05-14 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 31,997 | $0.00 |
| 2012-05-14 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 売却 | 16,667 | $0.00 |
| 2012-05-11 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 34,750 | $0.00 |
| 2012-05-11 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 11,119 | $0.00 |
| 2012-05-11 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 88,881 | $0.00 |
| 2012-05-11 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 5,556 | $0.00 |
| 2012-05-11 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 5,000 | $6.27 |
| 2012-05-11 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 2,083 | $5.97 |
| 2012-05-11 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 34,750 | $8.19 |
| 2012-05-11 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 11,119 | $8.99 |
| 2012-05-11 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 88,881 | $8.99 |
| 2012-05-11 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 5,556 | $7.09 |
| 2012-05-11 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 147,389 | $23.22 |
| 2012-05-11 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 5,000 | $0.00 |
| 2012-05-11 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 2,083 | $0.00 |
| 2012-05-07 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 普通株式 | 購入 | 225,000 | $5.97 |
| 2012-05-07 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | ストックオプション | 売却 | 225,000 | $0.00 |
| 2012-05-07 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 普通株式 | 売却 | 225,000 | $22.56 |
| 2012-05-01 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 13,976 | $22.70 |
| 2012-04-27 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 売却 | 8,440 | $0.00 |
| 2012-04-27 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 購入 | 8,440 | $8.19 |
| 2012-04-27 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 売却 | 30,000 | $22.95 |
| 2012-04-27 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 売却 | 11,809 | $0.00 |
| 2012-04-27 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 売却 | 9,751 | $0.00 |
| 2012-04-27 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 購入 | 11,809 | $8.99 |
| 2012-04-27 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 購入 | 9,751 | $8.99 |
| 2012-03-21 | WHITFIELD, ROY A | Director | 普通株式 | 購入 | 4,000 | $3.86 |
| 2012-03-21 | WHITFIELD, ROY A | Director | ストックオプション | 売却 | 10,000 | $0.00 |
| 2012-03-21 | WHITFIELD, ROY A | Director | ストックオプション | 売却 | 4,000 | $0.00 |
| 2012-03-21 | WHITFIELD, ROY A | Director | 普通株式 | 購入 | 10,000 | $4.44 |
| 2012-03-19 | WHITFIELD, ROY A | Director | 普通株式 | 購入 | 20,000 | $2.80 |
| 2012-03-19 | WHITFIELD, ROY A | Director | 普通株式 | 購入 | 16,000 | $3.86 |
| 2012-03-19 | WHITFIELD, ROY A | Director | ストックオプション | 売却 | 20,000 | $0.00 |
| 2012-03-19 | WHITFIELD, ROY A | Director | ストックオプション | 売却 | 16,000 | $0.00 |
| 2012-02-17 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 7,000 | $17.53 |
| 2012-02-17 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 600 | $17.51 |
| 2012-02-17 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 1,200 | $17.52 |
| 2012-02-17 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 2,300 | $17.50 |
| 2012-02-17 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 3,600 | $17.54 |
| 2012-02-17 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 700 | $17.56 |
| 2012-02-17 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 4,600 | $17.55 |
| 2012-01-31 | DE, SCHUTTER RICHARD U | Director, Chairman | 普通株式 | 購入 | 20,000 | $7.26 |
| 2012-01-31 | DE, SCHUTTER RICHARD U | Director, Chairman | 普通株式 | 購入 | 20,000 | $7.68 |
| 2012-01-31 | DE, SCHUTTER RICHARD U | Director, Chairman | ストックオプション | 売却 | 5,000 | $0.00 |
| 2012-01-31 | DE, SCHUTTER RICHARD U | Director, Chairman | ストックオプション | 売却 | 20,000 | $0.00 |
| 2012-01-31 | DE, SCHUTTER RICHARD U | Director, Chairman | 普通株式 | 購入 | 20,000 | $2.80 |
| 2012-01-31 | DE, SCHUTTER RICHARD U | Director, Chairman | 普通株式 | 購入 | 5,000 | $6.66 |
| 2012-01-19 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | ストックオプション | 購入 | 219,379 | $0.00 |
| 2012-01-19 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | ストックオプション | 購入 | 5,621 | $0.00 |
| 2012-01-19 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 93,900 | $0.00 |
| 2012-01-19 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 購入 | 72,588 | $0.00 |
| 2012-01-19 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 購入 | 93,900 | $0.00 |
| 2012-01-19 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 購入 | 6,100 | $0.00 |
| 2012-01-19 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 購入 | 5,813 | $0.00 |
| 2012-01-19 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 購入 | 34,187 | $0.00 |
| 2012-01-19 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 購入 | 6,100 | $0.00 |
| 2012-01-19 | ANDREWS, PATRICIA S | Chief Commercial Officer | ストックオプション | 購入 | 93,900 | $0.00 |
| 2012-01-19 | BROOKE, PAUL A | Director | 普通株式 | 購入 | 25,000 | $17.86 |
| 2012-01-19 | ANDREWS, PATRICIA S | Chief Commercial Officer | ストックオプション | 購入 | 6,100 | $0.00 |
| 2012-01-19 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 購入 | 2,412 | $0.00 |
| 2012-01-19 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 6,100 | $0.00 |
| 2012-01-19 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 購入 | 93,900 | $0.00 |
| 2012-01-18 | BROOKE, PAUL A | Director | 普通株式 | 購入 | 25,000 | $17.53 |
| 2012-01-13 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 1,965 | $16.58 |
| 2012-01-13 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 41,677 | $16.62 |
| 2012-01-13 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 72,978 | $16.58 |
| 2012-01-13 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 102,856 | $16.46 |
| 2012-01-13 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 1,122 | $16.62 |
| 2012-01-13 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 2,769 | $16.46 |
| 2012-01-12 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 5,919 | $16.21 |
| 2012-01-12 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 219,881 | $16.21 |
| 2012-01-12 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 105,847 | $16.38 |
| 2012-01-12 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 2,850 | $16.38 |
| 2011-12-20 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 普通株式 | 購入 | 100,000 | $0.00 |
| 2011-12-09 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 2,727 | $13.19 |
| 2011-12-09 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 4,789 | $13.26 |
| 2011-12-09 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 73 | $13.19 |
| 2011-12-09 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 178,474 | $13.26 |
| 2011-12-08 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 4,291 | $13.47 |
| 2011-12-08 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 159,925 | $13.47 |
| 2011-12-08 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 62,395 | $13.44 |
| 2011-12-08 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 1,674 | $13.44 |
| 2011-12-07 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 2,033 | $13.21 |
| 2011-12-07 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 75,948 | $13.21 |
| 2011-12-07 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 68,955 | $13.22 |
| 2011-12-07 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 1,845 | $13.22 |
| 2011-12-06 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 3,910 | $13.54 |
| 2011-12-06 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 192,316 | $13.52 |
| 2011-12-06 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 5,147 | $13.52 |
| 2011-12-06 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 146,090 | $13.54 |
| 2011-12-05 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 1,023,128 | $13.89 |
| 2011-12-05 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 1,303 | $13.88 |
| 2011-12-05 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 27,382 | $13.89 |
| 2011-12-05 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 48,697 | $13.88 |
| 2011-12-01 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 6,575 | $14.18 |
| 2011-12-01 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 267,768 | $13.78 |
| 2011-12-01 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 317,429 | $14.36 |
| 2011-12-01 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 243,425 | $14.18 |
| 2011-12-01 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 7,232 | $13.78 |
| 2011-12-01 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 8,573 | $14.36 |
| 2011-11-30 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 250,000 | $13.60 |
| 2011-11-30 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 257,911 | $13.29 |
| 2011-11-29 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 15,737 | $12.23 |
| 2011-11-29 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 582,677 | $12.23 |
| 2011-11-29 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 486,969 | $12.19 |
| 2011-11-29 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 13,153 | $12.19 |
| 2011-11-17 | DIXON, WENDY L | Director | 普通株式 | 購入 | 585 | $13.39 |
| 2011-11-17 | DIXON, WENDY L | Director | 普通株式 | 購入 | 2,338 | $13.41 |
| 2011-11-17 | DIXON, WENDY L | Director | 普通株式 | 購入 | 3,877 | $13.40 |
| 2011-11-17 | DIXON, WENDY L | Director | 普通株式 | 購入 | 700 | $13.37 |
| 2011-08-12 | DE, SCHUTTER RICHARD U | Director, Chairman | 普通株式 | 購入 | 225,000 | $ |
| 2011-08-09 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 購入 | 19,444 | $0.00 |
| 2011-08-09 | SIEGEL, ERIC H. | EVP, General Counsel | ストックオプション | 購入 | 5,556 | $0.00 |
| 2011-06-30 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 11,664 | $0.00 |
| 2011-06-30 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 11,664 | $0.00 |
| 2011-06-21 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 18,062 | $18.57 |
| 2011-06-21 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 100 | $18.66 |
| 2011-06-21 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 100 | $18.67 |
| 2011-06-21 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 200 | $18.68 |
| 2011-06-21 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 300 | $18.69 |
| 2011-06-21 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 7,900 | $18.70 |
| 2011-06-21 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 200 | $18.71 |
| 2011-06-21 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 売却 | 29,165 | $0.00 |
| 2011-06-21 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 売却 | 10,835 | $0.00 |
| 2011-06-21 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 100 | $18.60 |
| 2011-06-21 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 購入 | 10,835 | $5.46 |
| 2011-06-21 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 購入 | 29,165 | $5.46 |
| 2011-06-21 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 2,700 | $18.63 |
| 2011-06-21 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 700 | $18.62 |
| 2011-06-21 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 1,100 | $18.65 |
| 2011-06-21 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 2,938 | $18.61 |
| 2011-06-21 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 100 | $18.59 |
| 2011-06-21 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 5,500 | $18.58 |
| 2011-06-17 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 1,498 | $18.04 |
| 2011-06-17 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 400 | $18.08 |
| 2011-06-17 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 2,400 | $18.01 |
| 2011-06-17 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 2,100 | $18.02 |
| 2011-06-17 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 1,579 | $18.03 |
| 2011-06-17 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 4,700 | $18.00 |
| 2011-06-17 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 1,000 | $18.05 |
| 2011-06-17 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 1,321 | $18.06 |
| 2011-06-17 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 500 | $18.07 |
| 2011-06-16 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 600 | $18.04 |
| 2011-06-16 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 900 | $18.02 |
| 2011-06-16 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 1,102 | $18.01 |
| 2011-06-16 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 1,000 | $18.00 |
| 2011-06-16 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 900 | $18.03 |
| 2011-06-09 | HASTINGS, DAVID C | Chief Financial Officer | 普通株式 | 売却 | 25,000 | $17.70 |
| 2011-06-09 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 売却 | 18,124 | $0.00 |
| 2011-06-09 | HASTINGS, DAVID C | Chief Financial Officer | 普通株式 | 購入 | 100,000 | $5.12 |
| 2011-06-09 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 売却 | 81,876 | $0.00 |
| 2011-06-09 | HASTINGS, DAVID C | Chief Financial Officer | 普通株式 | 売却 | 25,000 | $17.76 |
| 2011-06-09 | HASTINGS, DAVID C | Chief Financial Officer | 普通株式 | 売却 | 25,000 | $17.75 |
| 2011-06-09 | HASTINGS, DAVID C | Chief Financial Officer | 普通株式 | 売却 | 25,000 | $17.73 |
| 2011-05-20 | ARIKO, BARRY A | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2011-05-20 | NIBLACK, JOHN F | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2011-05-20 | DIXON, WENDY L | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2011-05-20 | WHITFIELD, ROY A | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2011-05-20 | DE, SCHUTTER RICHARD U | Director, Chairman | ストックオプション | 購入 | 20,000 | $0.00 |
| 2011-05-20 | BROOKE, PAUL A | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2011-05-20 | BAKER, JULIAN | Director, 10% Owner | ストックオプション | 購入 | 20,000 | $0.00 |
| 2011-05-17 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 23,301 | $19.23 |
| 2011-05-17 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 75,000 | $13.80 |
| 2011-05-17 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 26,699 | $19.31 |
| 2011-05-17 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 25,000 | $19.36 |
| 2011-05-17 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 51,699 | $0.00 |
| 2011-05-17 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 23,301 | $0.00 |
| 2011-05-12 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 100 | $20.08 |
| 2011-05-12 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 300 | $20.01 |
| 2011-05-12 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 100 | $20.02 |
| 2011-05-12 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 100 | $20.03 |
| 2011-05-12 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 100 | $20.07 |
| 2011-05-12 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 100 | $20.14 |
| 2011-05-12 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 100 | $20.15 |
| 2011-05-12 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 100 | $20.16 |
| 2011-05-12 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 100 | $20.17 |
| 2011-05-12 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 200 | $20.19 |
| 2011-05-12 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 100 | $20.20 |
| 2011-05-12 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 100 | $20.21 |
| 2011-05-12 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 100 | $20.22 |
| 2011-05-12 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 400 | $20.23 |
| 2011-05-12 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 200 | $20.24 |
| 2011-05-12 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 100 | $20.25 |
| 2011-05-12 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 200 | $20.26 |
| 2011-05-12 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 100 | $20.28 |
| 2011-05-12 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 100 | $20.29 |
| 2011-05-12 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 3,399 | $20.33 |
| 2011-05-12 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 200 | $20.34 |
| 2011-05-12 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 3,203 | $20.35 |
| 2011-05-12 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 268 | $20.36 |
| 2011-05-12 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 30 | $20.37 |
| 2011-05-12 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 200 | $20.39 |
| 2011-05-11 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 600 | $20.03 |
| 2011-05-11 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 1,700 | $20.04 |
| 2011-05-11 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 2,200 | $20.00 |
| 2011-05-11 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 3,702 | $20.01 |
| 2011-05-11 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 1,798 | $20.02 |
| 2011-05-10 | SCHRECK, PATRICIA A | EVP, General Counsel | 普通株式 | 売却 | 10,000 | $20.57 |
| 2011-05-10 | SCHRECK, PATRICIA A | EVP, General Counsel | 普通株式 | 売却 | 10,000 | $20.66 |
| 2011-05-10 | SCHRECK, PATRICIA A | EVP, General Counsel | 普通株式 | 売却 | 10,000 | $20.67 |
| 2011-05-10 | SCHRECK, PATRICIA A | EVP, General Counsel | ストックオプション | 売却 | 50,000 | $0.00 |
| 2011-05-10 | SCHRECK, PATRICIA A | EVP, General Counsel | 普通株式 | 売却 | 50,000 | $5.46 |
| 2011-05-10 | SCHRECK, PATRICIA A | EVP, General Counsel | 普通株式 | 売却 | 10,000 | $20.50 |
| 2011-05-10 | SCHRECK, PATRICIA A | EVP, General Counsel | 普通株式 | 売却 | 10,000 | $20.51 |
| 2011-05-09 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 100 | $19.80 |
| 2011-05-09 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 4,300 | $19.81 |
| 2011-05-09 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 900 | $19.76 |
| 2011-05-09 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 316 | $19.78 |
| 2011-05-09 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 1,400 | $19.75 |
| 2011-05-09 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 800 | $19.77 |
| 2011-05-09 | SCHRECK, PATRICIA A | EVP, General Counsel | 普通株式 | 購入 | 50,000 | $6.15 |
| 2011-05-09 | SCHRECK, PATRICIA A | EVP, General Counsel | 普通株式 | 売却 | 50,000 | $19.90 |
| 2011-05-09 | SCHRECK, PATRICIA A | EVP, General Counsel | ストックオプション | 売却 | 50,000 | $0.00 |
| 2011-05-09 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 2,184 | $19.79 |
| 2011-05-06 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 5,343 | $19.55 |
| 2011-05-05 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 300 | $19.24 |
| 2011-05-05 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 2,990 | $19.26 |
| 2011-05-05 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 100 | $19.31 |
| 2011-05-05 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 2,800 | $19.20 |
| 2011-05-05 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 1,700 | $19.22 |
| 2011-05-05 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 610 | $19.23 |
| 2011-05-05 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 1,500 | $19.25 |
| 2011-04-11 | METCALF, BRIAN W | Chief Drug Discovery Scientist | 普通株式 | 売却 | 50,000 | $17.42 |
| 2011-04-11 | METCALF, BRIAN W | Chief Drug Discovery Scientist | 普通株式 | 購入 | 100,000 | $5.46 |
| 2011-04-11 | METCALF, BRIAN W | Chief Drug Discovery Scientist | 普通株式 | 売却 | 50,000 | $17.40 |
| 2011-04-11 | METCALF, BRIAN W | Chief Drug Discovery Scientist | ストックオプション | 売却 | 82,688 | $0.00 |
| 2011-04-11 | METCALF, BRIAN W | Chief Drug Discovery Scientist | ストックオプション | 売却 | 17,312 | $0.00 |
| 2011-04-08 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 売却 | 3,335 | $0.00 |
| 2011-04-08 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 売却 | 21,665 | $0.00 |
| 2011-04-08 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 100 | $17.06 |
| 2011-04-08 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 506 | $17.05 |
| 2011-04-08 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 100 | $17.04 |
| 2011-04-08 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 購入 | 21,665 | $3.11 |
| 2011-04-08 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 購入 | 3,335 | $3.11 |
| 2011-04-08 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 21,194 | $17.00 |
| 2011-04-08 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 200 | $17.02 |
| 2011-04-08 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 2,900 | $17.03 |
| 2011-04-07 | SCHRECK, PATRICIA A | EVP, General Counsel | ストックオプション | 売却 | 69,532 | $0.00 |
| 2011-04-07 | SCHRECK, PATRICIA A | EVP, General Counsel | 普通株式 | 購入 | 30,468 | $5.46 |
| 2011-04-07 | SCHRECK, PATRICIA A | EVP, General Counsel | 普通株式 | 購入 | 69,532 | $3.11 |
| 2011-04-07 | SCHRECK, PATRICIA A | EVP, General Counsel | 普通株式 | 売却 | 100,000 | $16.50 |
| 2011-04-07 | SCHRECK, PATRICIA A | EVP, General Counsel | ストックオプション | 売却 | 30,468 | $0.00 |
| 2011-04-05 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 300 | $16.00 |
| 2011-04-05 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 1,400 | $16.03 |
| 2011-04-05 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 7,700 | $16.01 |
| 2011-04-05 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 200 | $16.04 |
| 2011-04-05 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 400 | $16.05 |
| 2011-03-25 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 100 | $14.73 |
| 2011-03-25 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 300 | $14.72 |
| 2011-03-25 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 100 | $14.70 |
| 2011-03-25 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 200 | $14.67 |
| 2011-03-25 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 400 | $14.65 |
| 2011-03-25 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 1,500 | $14.63 |
| 2011-03-25 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 1,300 | $14.62 |
| 2011-03-25 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 1,500 | $14.61 |
| 2011-03-25 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 2,700 | $14.60 |
| 2011-03-25 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 600 | $14.76 |
| 2011-03-25 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 100 | $14.77 |
| 2011-03-25 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 700 | $14.83 |
| 2011-03-25 | ARIKO, BARRY A | Director | 普通株式 | 購入 | 20,834 | $14.13 |
| 2011-03-25 | ARIKO, BARRY A | Director | ストックオプション | 売却 | 834 | $0.00 |
| 2011-03-25 | ARIKO, BARRY A | Director | ストックオプション | 売却 | 20,000 | $0.00 |
| 2011-03-25 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 500 | $14.75 |
| 2011-03-18 | METCALF, BRIAN W | Chief Drug Discovery Scientist | 普通株式 | 購入 | 50,000 | $11.06 |
| 2011-03-18 | METCALF, BRIAN W | Chief Drug Discovery Scientist | ストックオプション | 売却 | 50,000 | $0.00 |
| 2011-03-18 | METCALF, BRIAN W | Chief Drug Discovery Scientist | ストックオプション | 売却 | 73,433 | $0.00 |
| 2011-03-18 | METCALF, BRIAN W | Chief Drug Discovery Scientist | ストックオプション | 売却 | 33,790 | $0.00 |
| 2011-03-18 | METCALF, BRIAN W | Chief Drug Discovery Scientist | ストックオプション | 売却 | 2,777 | $0.00 |
| 2011-03-18 | METCALF, BRIAN W | Chief Drug Discovery Scientist | 普通株式 | 購入 | 73,433 | $11.06 |
| 2011-03-18 | METCALF, BRIAN W | Chief Drug Discovery Scientist | 普通株式 | 購入 | 33,790 | $11.06 |
| 2011-03-18 | METCALF, BRIAN W | Chief Drug Discovery Scientist | 普通株式 | 購入 | 2,777 | $5.97 |
| 2011-03-18 | METCALF, BRIAN W | Chief Drug Discovery Scientist | 普通株式 | 売却 | 58,300 | $14.30 |
| 2011-03-18 | METCALF, BRIAN W | Chief Drug Discovery Scientist | 普通株式 | 売却 | 51,500 | $14.25 |
| 2011-03-18 | METCALF, BRIAN W | Chief Drug Discovery Scientist | 普通株式 | 売却 | 200 | $14.31 |
| 2011-03-18 | METCALF, BRIAN W | Chief Drug Discovery Scientist | 普通株式 | 売却 | 50,000 | $14.25 |
| 2011-03-16 | METCALF, BRIAN W | Chief Drug Discovery Scientist | 普通株式 | 購入 | 47,223 | $5.97 |
| 2011-03-16 | METCALF, BRIAN W | Chief Drug Discovery Scientist | ストックオプション | 売却 | 2,777 | $0.00 |
| 2011-03-16 | METCALF, BRIAN W | Chief Drug Discovery Scientist | ストックオプション | 売却 | 47,223 | $0.00 |
| 2011-03-16 | METCALF, BRIAN W | Chief Drug Discovery Scientist | 普通株式 | 売却 | 50,000 | $14.25 |
| 2011-03-16 | METCALF, BRIAN W | Chief Drug Discovery Scientist | 普通株式 | 購入 | 2,777 | $11.06 |
| 2011-03-10 | DE, SCHUTTER RICHARD U | Director, Chairman | 普通株式 | 購入 | 150,000 | $ |
| 2011-02-23 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 普通株式 | 購入 | 20,000 | $8.64 |
| 2011-02-23 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | ストックオプション | 売却 | 20,000 | $0.00 |
| 2011-02-17 | METCALF, BRIAN W | Chief Drug Discovery Scientist | 普通株式 | 購入 | 50,000 | $5.97 |
| 2011-02-17 | METCALF, BRIAN W | Chief Drug Discovery Scientist | 普通株式 | 売却 | 50,000 | $14.35 |
| 2011-02-17 | METCALF, BRIAN W | Chief Drug Discovery Scientist | ストックオプション | 売却 | 50,000 | $0.00 |
| 2011-02-15 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 4,534,000 | $51.03 |
| 2011-02-15 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 206,000 | $52.76 |
| 2011-02-15 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 124,000 | $51.03 |
| 2011-02-15 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 7,598,000 | $52.76 |
| 2011-01-25 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | ストックオプション | 購入 | 290,189 | $0.00 |
| 2011-01-25 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 購入 | 7,683 | $0.00 |
| 2011-01-25 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 購入 | 92,317 | $0.00 |
| 2011-01-25 | ANDREWS, PATRICIA S | Chief Commercial Officer | ストックオプション | 購入 | 4,743 | $0.00 |
| 2011-01-25 | ANDREWS, PATRICIA S | Chief Commercial Officer | ストックオプション | 購入 | 95,257 | $0.00 |
| 2011-01-25 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 購入 | 7,150 | $0.00 |
| 2011-01-25 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 購入 | 32,850 | $0.00 |
| 2011-01-25 | SCHRECK, PATRICIA A | EVP, General Counsel | ストックオプション | 購入 | 7,683 | $0.00 |
| 2011-01-25 | SCHRECK, PATRICIA A | EVP, General Counsel | ストックオプション | 購入 | 92,317 | $0.00 |
| 2011-01-25 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 購入 | 7,683 | $0.00 |
| 2011-01-25 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 購入 | 92,317 | $0.00 |
| 2011-01-25 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 7,683 | $0.00 |
| 2011-01-25 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 92,317 | $0.00 |
| 2011-01-25 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | ストックオプション | 購入 | 9,811 | $0.00 |
| 2011-01-18 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 売却 | 15,000 | $0.00 |
| 2011-01-18 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 売却 | 25,310 | $0.00 |
| 2011-01-18 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 購入 | 15,000 | $4.19 |
| 2011-01-18 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 売却 | 6,400 | $15.77 |
| 2011-01-18 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 購入 | 25,310 | $8.19 |
| 2011-01-18 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 売却 | 10,000 | $15.79 |
| 2011-01-18 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 売却 | 616 | $16.01 |
| 2011-01-18 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 売却 | 1,494 | $15.82 |
| 2011-01-18 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 売却 | 8,200 | $15.81 |
| 2011-01-18 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 売却 | 13,600 | $15.80 |
| 2010-12-23 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 400 | $17.15 |
| 2010-12-23 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 100 | $17.17 |
| 2010-12-23 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 8,100 | $17.00 |
| 2010-12-23 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 400 | $17.01 |
| 2010-12-23 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 100 | $17.13 |
| 2010-12-23 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 500 | $17.14 |
| 2010-12-23 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 400 | $17.16 |
| 2010-12-22 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 10,000 | $17.00 |
| 2010-11-17 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 1,000 | $15.90 |
| 2010-11-16 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 6,541 | $16.00 |
| 2010-11-16 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 2,759 | $16.01 |
| 2010-11-16 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 700 | $16.02 |
| 2010-10-25 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 5,400 | $16.95 |
| 2010-10-25 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 2,700 | $16.93 |
| 2010-10-25 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 3,600 | $16.94 |
| 2010-10-25 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 3,915 | $16.96 |
| 2010-10-25 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 4,055 | $16.97 |
| 2010-10-25 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 200 | $16.98 |
| 2010-10-25 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 300 | $16.99 |
| 2010-10-25 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 4,400 | $17.00 |
| 2010-10-25 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 600 | $17.01 |
| 2010-10-25 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 300 | $17.02 |
| 2010-10-25 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 2,900 | $17.03 |
| 2010-10-25 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 1,000 | $17.04 |
| 2010-10-25 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 153 | $17.05 |
| 2010-10-22 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 4,730 | $16.95 |
| 2010-09-23 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 3,820 | $14.86 |
| 2010-09-23 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 5,681 | $14.86 |
| 2010-09-23 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 5,722 | $14.86 |
| 2010-09-23 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 179,644 | $14.86 |
| 2010-09-23 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 70,150 | $14.86 |
| 2010-09-22 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 7,180 | $14.71 |
| 2010-09-22 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 227,071 | $14.71 |
| 2010-09-22 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 4,829 | $14.71 |
| 2010-09-22 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 7,233 | $14.71 |
| 2010-09-22 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 88,670 | $14.71 |
| 2010-09-21 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 19,433 | $14.94 |
| 2010-09-21 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 610,072 | $14.94 |
| 2010-09-21 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 19,291 | $14.94 |
| 2010-09-21 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 12,974 | $14.94 |
| 2010-09-21 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 238,230 | $14.94 |
| 2010-08-10 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 1,856 | $14.00 |
| 2010-08-10 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 58,262 | $14.00 |
| 2010-08-10 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 947 | $14.00 |
| 2010-08-10 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 1,842 | $14.00 |
| 2010-08-10 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 29,988 | $14.00 |
| 2010-08-10 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 22,751 | $14.00 |
| 2010-08-10 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 11,711 | $14.00 |
| 2010-08-10 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 1,239 | $14.00 |
| 2010-08-10 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 638 | $14.00 |
| 2010-08-10 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 956 | $14.00 |
| 2010-08-09 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 74,201 | $14.08 |
| 2010-08-09 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 2,500 | $14.06 |
| 2010-08-09 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 48,266 | $14.09 |
| 2010-08-09 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 190,020 | $14.08 |
| 2010-08-09 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 123,602 | $14.09 |
| 2010-08-09 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 3,938 | $14.09 |
| 2010-08-09 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 2,200 | $14.07 |
| 2010-08-09 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 9,818 | $14.05 |
| 2010-08-09 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 4,041 | $14.08 |
| 2010-08-09 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 売却 | 1,100 | $14.08 |
| 2010-08-09 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 6,053 | $14.08 |
| 2010-08-09 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 3,907 | $14.09 |
| 2010-08-09 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 6,009 | $14.08 |
| 2010-08-09 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 2,629 | $14.09 |
| 2010-08-06 | SCHRECK, PATRICIA A | EVP, General Counsel | 普通株式 | 購入 | 94,960 | $6.15 |
| 2010-08-06 | SCHRECK, PATRICIA A | EVP, General Counsel | ストックオプション | 売却 | 94,960 | $0.00 |
| 2010-08-06 | SCHRECK, PATRICIA A | EVP, General Counsel | 普通株式 | 売却 | 8,900 | $13.89 |
| 2010-08-06 | SCHRECK, PATRICIA A | EVP, General Counsel | 普通株式 | 売却 | 10,600 | $13.92 |
| 2010-08-06 | SCHRECK, PATRICIA A | EVP, General Counsel | 普通株式 | 売却 | 7,689 | $13.87 |
| 2010-08-06 | SCHRECK, PATRICIA A | EVP, General Counsel | 普通株式 | 売却 | 492 | $13.82 |
| 2010-08-06 | SCHRECK, PATRICIA A | EVP, General Counsel | 普通株式 | 売却 | 7,800 | $13.91 |
| 2010-08-06 | SCHRECK, PATRICIA A | EVP, General Counsel | 普通株式 | 売却 | 1,360 | $13.81 |
| 2010-08-06 | SCHRECK, PATRICIA A | EVP, General Counsel | 普通株式 | 売却 | 25,885 | $13.88 |
| 2010-08-06 | SCHRECK, PATRICIA A | EVP, General Counsel | 普通株式 | 売却 | 600 | $13.80 |
| 2010-08-06 | SCHRECK, PATRICIA A | EVP, General Counsel | 普通株式 | 売却 | 1,499 | $13.83 |
| 2010-08-06 | SCHRECK, PATRICIA A | EVP, General Counsel | 普通株式 | 売却 | 13,430 | $13.90 |
| 2010-08-06 | SCHRECK, PATRICIA A | EVP, General Counsel | 普通株式 | 売却 | 6,000 | $13.86 |
| 2010-08-06 | SCHRECK, PATRICIA A | EVP, General Counsel | 普通株式 | 売却 | 6,200 | $13.85 |
| 2010-08-06 | SCHRECK, PATRICIA A | EVP, General Counsel | 普通株式 | 売却 | 4,505 | $13.84 |
| 2010-07-07 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 普通株式 | 購入 | 10,895 | $7.09 |
| 2010-07-07 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | ストックオプション | 売却 | 10,895 | $0.00 |
| 2010-07-07 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | ストックオプション | 売却 | 14,247 | $0.00 |
| 2010-07-07 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 普通株式 | 購入 | 14,247 | $5.46 |
| 2010-07-01 | HASTINGS, DAVID C | Chief Financial Officer | 普通株式 | 購入 | 2,000 | $10.24 |
| 2010-07-01 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 普通株式 | 購入 | 5,697 | $10.43 |
| 2010-07-01 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 普通株式 | 購入 | 4,303 | $10.42 |
| 2010-06-17 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 72,917 | $0.00 |
| 2010-06-17 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 25,000 | $6.27 |
| 2010-06-17 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 売却 | 97,917 | $13.15 |
| 2010-06-17 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 72,917 | $5.97 |
| 2010-06-17 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 売却 | 25,000 | $0.00 |
| 2010-05-21 | DIXON, WENDY L | Director | ストックオプション | 購入 | 18,334 | $0.00 |
| 2010-05-21 | DIXON, WENDY L | Director | ストックオプション | 購入 | 35,000 | $0.00 |
| 2010-05-21 | ANDREWS, PATRICIA S | Chief Commercial Officer | ストックオプション | 購入 | 21,527 | $0.00 |
| 2010-05-21 | ANDREWS, PATRICIA S | Chief Commercial Officer | ストックオプション | 購入 | 3,473 | $0.00 |
| 2010-05-18 | ARIKO, BARRY A | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2010-05-18 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | ストックオプション | 購入 | 834 | $0.00 |
| 2010-05-18 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | ストックオプション | 購入 | 29,166 | $0.00 |
| 2010-05-18 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 417 | $0.00 |
| 2010-05-18 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 14,583 | $0.00 |
| 2010-05-18 | METCALF, BRIAN W | Chief Drug Discovery Scientist | ストックオプション | 購入 | 417 | $0.00 |
| 2010-05-18 | METCALF, BRIAN W | Chief Drug Discovery Scientist | ストックオプション | 購入 | 14,583 | $0.00 |
| 2010-05-18 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 購入 | 417 | $0.00 |
| 2010-05-18 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 購入 | 14,583 | $0.00 |
| 2010-05-18 | SCHRECK, PATRICIA A | EVP, General Counsel | ストックオプション | 購入 | 417 | $0.00 |
| 2010-05-18 | SCHRECK, PATRICIA A | EVP, General Counsel | ストックオプション | 購入 | 14,583 | $0.00 |
| 2010-05-18 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 購入 | 5,833 | $0.00 |
| 2010-05-18 | ANDREWS, PATRICIA S | Chief Commercial Officer | ストックオプション | 購入 | 417 | $0.00 |
| 2010-05-18 | ANDREWS, PATRICIA S | Chief Commercial Officer | ストックオプション | 購入 | 14,583 | $0.00 |
| 2010-05-18 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 購入 | 417 | $0.00 |
| 2010-05-18 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 購入 | 14,583 | $0.00 |
| 2010-05-18 | FRIEDMAN, STEVEN M. | EVP, Biology & Preclinical Dev | ストックオプション | 購入 | 417 | $0.00 |
| 2010-05-18 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 購入 | 167 | $0.00 |
| 2010-05-18 | FRIEDMAN, STEVEN M. | EVP, Biology & Preclinical Dev | ストックオプション | 購入 | 14,583 | $0.00 |
| 2010-05-18 | NIBLACK, JOHN F | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2010-05-18 | BAKER, JULIAN | Director, 10% Owner | ストックオプション | 購入 | 20,000 | $0.00 |
| 2010-05-18 | BROOKE, PAUL A | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2010-05-18 | DE, SCHUTTER RICHARD U | Director, Chairman | ストックオプション | 購入 | 20,000 | $0.00 |
| 2010-05-18 | WHITFIELD, ROY A | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2010-03-15 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 購入 | 20,000 | $4.19 |
| 2010-03-15 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | 普通株式 | 売却 | 20,000 | $12.94 |
| 2010-03-15 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 売却 | 20,000 | $0.00 |
| 2010-01-21 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 購入 | 19,406 | $0.00 |
| 2010-01-21 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 購入 | 14,594 | $0.00 |
| 2010-01-21 | SCHRECK, PATRICIA A | EVP, General Counsel | ストックオプション | 購入 | 72,930 | $0.00 |
| 2010-01-21 | SCHRECK, PATRICIA A | EVP, General Counsel | ストックオプション | 購入 | 12,070 | $0.00 |
| 2010-01-21 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 購入 | 72,930 | $0.00 |
| 2010-01-21 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 購入 | 12,070 | $0.00 |
| 2010-01-21 | METCALF, BRIAN W | Chief Drug Discovery Scientist | ストックオプション | 購入 | 72,930 | $0.00 |
| 2010-01-21 | METCALF, BRIAN W | Chief Drug Discovery Scientist | ストックオプション | 購入 | 12,070 | $0.00 |
| 2010-01-21 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 72,930 | $0.00 |
| 2010-01-21 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 12,070 | $0.00 |
| 2010-01-21 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | ストックオプション | 購入 | 156,487 | $0.00 |
| 2010-01-21 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | ストックオプション | 購入 | 13,513 | $0.00 |
| 2010-01-21 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 購入 | 12,300 | $0.00 |
| 2010-01-21 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 購入 | 72,700 | $0.00 |
| 2010-01-21 | FRIEDMAN, STEVEN M. | EVP, Biology & Preclinical Dev | ストックオプション | 購入 | 72,700 | $0.00 |
| 2010-01-21 | FRIEDMAN, STEVEN M. | EVP, Biology & Preclinical Dev | ストックオプション | 購入 | 12,300 | $0.00 |
| 2010-01-21 | ANDREWS, PATRICIA S | Chief Commercial Officer | ストックオプション | 購入 | 72,930 | $0.00 |
| 2010-01-21 | ANDREWS, PATRICIA S | Chief Commercial Officer | ストックオプション | 購入 | 12,070 | $0.00 |
| 2010-01-08 | FRIEDMAN, STEVEN M. | EVP, Biology & Preclinical Dev | 普通株式 | 売却 | 22,000 | $10.90 |
| 2009-09-24 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 101,506 | $6.75 |
| 2009-09-24 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 29,593,000 | $100.00 |
| 2009-09-24 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 878,000 | $97.88 |
| 2009-09-24 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 188,000 | $100.00 |
| 2009-09-24 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 470,000 | $98.74 |
| 2009-09-24 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 335,000 | $97.88 |
| 2009-09-24 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 50,294 | $6.75 |
| 2009-09-24 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 64,000 | $98.74 |
| 2009-09-24 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 294,000 | $97.88 |
| 2009-09-24 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 989,000 | $98.74 |
| 2009-09-24 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 3,478,000 | $100.00 |
| 2009-09-24 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 3,597,000 | $98.74 |
| 2009-09-24 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 15,055,000 | $97.88 |
| 2009-09-24 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 33,130,000 | $98.74 |
| 2009-09-24 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 売却 | 42,509,000 | $97.88 |
| 2009-09-24 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 124,687,000 | $100.00 |
| 2009-09-24 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 1,848,200 | $6.75 |
| 2009-09-24 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 2,054,000 | $100.00 |
| 2009-05-19 | NIBLACK, JOHN F | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2009-05-19 | ARIKO, BARRY A | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2009-05-19 | WHITFIELD, ROY A | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2009-05-19 | DE, SCHUTTER RICHARD U | Director, Chairman | ストックオプション | 購入 | 20,000 | $0.00 |
| 2009-05-19 | BROOKE, PAUL A | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2009-05-19 | BAKER, JULIAN | Director, 10% Owner | ストックオプション | 購入 | 20,000 | $0.00 |
| 2009-03-09 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 普通株式 | 購入 | 9,400 | $2.10 |
| 2009-03-06 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 普通株式 | 購入 | 10,600 | $2.10 |
| 2009-03-05 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 1,248 | $2.16 |
| 2009-03-05 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 485,000 | $50.97 |
| 2009-03-05 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 5 | $2.16 |
| 2009-03-05 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 388,000 | $48.45 |
| 2009-03-05 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 11,232 | $2.16 |
| 2009-03-05 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 3,493,000 | $48.45 |
| 2009-03-05 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 4,367,000 | $50.97 |
| 2009-03-05 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 121,000 | $50.97 |
| 2009-03-05 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 97,000 | $48.45 |
| 2009-03-05 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 64 | $2.16 |
| 2009-03-05 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 20,000 | $48.45 |
| 2009-03-05 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 2,000 | $48.45 |
| 2009-03-05 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 312 | $2.16 |
| 2009-03-05 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 25,000 | $50.97 |
| 2009-03-05 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 2,000 | $50.97 |
| 2009-03-05 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 普通株式 | 購入 | 8,840 | $2.20 |
| 2009-03-04 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 788,000 | $49.50 |
| 2009-03-04 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 8,000 | $49.50 |
| 2009-03-04 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 22,000 | $49.50 |
| 2009-03-04 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 182,000 | $49.50 |
| 2009-03-03 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 2,199 | $2.14 |
| 2009-03-03 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 546,000 | $48.13 |
| 2009-03-03 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 98 | $2.14 |
| 2009-03-03 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 24,000 | $48.13 |
| 2009-03-03 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 66,000 | $48.13 |
| 2009-03-03 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 普通株式 | 購入 | 11,160 | $2.20 |
| 2009-03-03 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 2,363,000 | $48.13 |
| 2009-03-03 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 9,524 | $2.14 |
| 2009-03-03 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 1,000 | $48.13 |
| 2009-03-03 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 5 | $2.14 |
| 2009-03-03 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 264 | $2.14 |
| 2009-03-02 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 15,951 | $2.17 |
| 2009-03-02 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 8 | $2.17 |
| 2009-03-02 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 1,818,000 | $48.13 |
| 2009-03-02 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 443 | $2.17 |
| 2009-03-02 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 9 | $2.14 |
| 2009-03-02 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 4,000 | $48.13 |
| 2009-03-02 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 164 | $2.17 |
| 2009-03-02 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 4,019 | $2.14 |
| 2009-03-02 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 484 | $2.14 |
| 2009-03-02 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 81,000 | $48.13 |
| 2009-03-02 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 3,682 | $2.17 |
| 2009-03-02 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 7,878,000 | $48.13 |
| 2009-03-02 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 219,000 | $48.13 |
| 2009-03-02 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 17,413 | $2.14 |
| 2009-03-02 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 179 | $2.14 |
| 2009-02-27 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 83,000 | $49.25 |
| 2009-02-27 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 2,000 | $49.25 |
| 2009-02-27 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 2,993,000 | $49.25 |
| 2009-02-27 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 21,000 | $49.13 |
| 2009-02-27 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 1,969,000 | $49.13 |
| 2009-02-27 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 31,000 | $49.25 |
| 2009-02-27 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 454,000 | $49.13 |
| 2009-02-27 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 55,000 | $49.13 |
| 2009-02-27 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 1,000 | $49.13 |
| 2009-02-27 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 691,000 | $49.25 |
| 2009-02-26 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 1,761,000 | $49.35 |
| 2009-02-26 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 4,000 | $49.35 |
| 2009-02-26 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 7,627,000 | $49.35 |
| 2009-02-26 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 212,000 | $49.35 |
| 2009-02-26 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 78,000 | $49.35 |
| 2009-01-27 | ANDREWS, PATRICIA S | Chief Commercial Officer | ストックオプション | 購入 | 2,780 | $0.00 |
| 2009-01-27 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 購入 | 14,447 | $0.00 |
| 2009-01-27 | FRIEDMAN, STEVEN M. | EVP, Biology & Preclinical Dev | ストックオプション | 購入 | 13,904 | $0.00 |
| 2009-01-27 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 購入 | 61,096 | $0.00 |
| 2009-01-27 | LEVY, RICHARD S | EVP, Chief Drug Dev&Medical Of | ストックオプション | 購入 | 13,904 | $0.00 |
| 2009-01-27 | SCHRECK, PATRICIA A | EVP, General Counsel | ストックオプション | 購入 | 86,469 | $0.00 |
| 2009-01-27 | SCHRECK, PATRICIA A | EVP, General Counsel | ストックオプション | 購入 | 13,531 | $0.00 |
| 2009-01-27 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 購入 | 86,469 | $0.00 |
| 2009-01-27 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 購入 | 13,531 | $0.00 |
| 2009-01-27 | METCALF, BRIAN W | Chief Drug Discovery Scientist | ストックオプション | 購入 | 86,469 | $0.00 |
| 2009-01-27 | METCALF, BRIAN W | Chief Drug Discovery Scientist | ストックオプション | 購入 | 13,531 | $0.00 |
| 2009-01-27 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 86,469 | $0.00 |
| 2009-01-27 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 13,531 | $0.00 |
| 2009-01-27 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | ストックオプション | 購入 | 194,444 | $0.00 |
| 2009-01-27 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | ストックオプション | 購入 | 5,556 | $0.00 |
| 2009-01-27 | FRIEDMAN, STEVEN M. | EVP, Biology & Preclinical Dev | ストックオプション | 購入 | 61,096 | $0.00 |
| 2009-01-27 | ANDREWS, PATRICIA S | Chief Commercial Officer | ストックオプション | 購入 | 97,220 | $0.00 |
| 2009-01-27 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 購入 | 25,553 | $0.00 |
| 2008-12-22 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 3 | $3.25 |
| 2008-12-22 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 85 | $3.25 |
| 2008-12-22 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 12 | $3.25 |
| 2008-12-19 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 206,000 | $52.76 |
| 2008-12-19 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 52,000 | $52.76 |
| 2008-12-19 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 31,000 | $51.03 |
| 2008-12-19 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 1,235 | $3.60 |
| 2008-12-19 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 219 | $3.62 |
| 2008-12-19 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 1,637 | $3.60 |
| 2008-12-19 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 290 | $3.62 |
| 2008-12-19 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 7,598,000 | $52.76 |
| 2008-12-19 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 4,534,000 | $51.03 |
| 2008-12-19 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 241,712 | $3.60 |
| 2008-12-19 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 42,834 | $3.62 |
| 2008-12-19 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 60 | $3.62 |
| 2008-12-19 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 124,000 | $51.03 |
| 2008-12-19 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 6,602 | $3.60 |
| 2008-12-19 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 1,170 | $3.62 |
| 2008-12-19 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 11,000 | $52.76 |
| 2008-12-19 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 2,383,000 | $52.76 |
| 2008-12-19 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 1,422,000 | $51.03 |
| 2008-12-19 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 75,808 | $3.60 |
| 2008-12-19 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 13,433 | $3.62 |
| 2008-12-19 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 6,000 | $51.03 |
| 2008-12-19 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 337 | $3.60 |
| 2008-12-18 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 2,436,000 | $52.84 |
| 2008-12-18 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 8 | $3.60 |
| 2008-12-18 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 125 | $3.56 |
| 2008-12-18 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 1,000 | $52.84 |
| 2008-12-18 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 3,904 | $3.60 |
| 2008-12-18 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 64,559 | $3.56 |
| 2008-12-18 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 729,000 | $52.84 |
| 2008-12-18 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 18,000 | $52.84 |
| 2008-12-18 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 355 | $3.60 |
| 2008-12-18 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 5,897 | $3.56 |
| 2008-12-18 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 66,000 | $52.84 |
| 2008-12-18 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 1,535 | $3.56 |
| 2008-12-18 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 93 | $3.60 |
| 2008-12-18 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 13,055 | $3.60 |
| 2008-12-18 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 215,917 | $3.56 |
| 2008-12-17 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 41,510 | $3.33 |
| 2008-12-17 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 9,259 | $3.15 |
| 2008-12-17 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 80,201 | $3.33 |
| 2008-12-17 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 13 | $3.15 |
| 2008-12-17 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 254 | $3.15 |
| 2008-12-17 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 184 | $3.33 |
| 2008-12-17 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 112 | $3.33 |
| 2008-12-17 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 2,903 | $3.15 |
| 2008-12-17 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 25,153 | $3.33 |
| 2008-12-17 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 896 | $3.33 |
| 2008-12-17 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 132,354 | $3.33 |
| 2008-12-17 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 3,616 | $3.33 |
| 2008-12-17 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 2,191 | $3.33 |
| 2008-12-17 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 62 | $3.15 |
| 2008-12-17 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 543 | $3.33 |
| 2008-11-21 | METCALF, BRIAN W | Chief Drug Discovery Scientist | 普通株式 | 購入 | 3,100 | $2.20 |
| 2008-11-21 | METCALF, BRIAN W | Chief Drug Discovery Scientist | 普通株式 | 購入 | 1,400 | $2.17 |
| 2008-11-21 | METCALF, BRIAN W | Chief Drug Discovery Scientist | 普通株式 | 購入 | 200 | $2.19 |
| 2008-11-21 | METCALF, BRIAN W | Chief Drug Discovery Scientist | 普通株式 | 購入 | 300 | $2.18 |
| 2008-11-20 | FRIEDMAN, PAUL A | Chief Executive Officer | 普通株式 | 購入 | 600 | $2.55 |
| 2008-11-20 | HASTINGS, DAVID C | Chief Financial Officer | 普通株式 | 購入 | 4,000 | $2.36 |
| 2008-11-20 | SCHRECK, PATRICIA A | EVP, General Counsel | 普通株式 | 購入 | 2,500 | $2.44 |
| 2008-11-20 | FRIEDMAN, PAUL A | Chief Executive Officer | 普通株式 | 購入 | 12,400 | $2.55 |
| 2008-11-20 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 購入 | 300 | $2.70 |
| 2008-11-20 | CHARDONNET, LAURENT | Vice President and Treasurer | 普通株式 | 購入 | 7,700 | $2.71 |
| 2008-10-21 | ANDREWS, PATRICIA S | Chief Commercial Officer | ストックオプション | 購入 | 52,815 | $0.00 |
| 2008-10-21 | ANDREWS, PATRICIA S | Chief Commercial Officer | ストックオプション | 購入 | 167,185 | $0.00 |
| 2008-10-15 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 普通株式 | 購入 | 5,300 | $4.60 |
| 2008-10-14 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 普通株式 | 購入 | 1,900 | $5.34 |
| 2008-10-14 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 普通株式 | 購入 | 2,800 | $5.35 |
| 2008-07-31 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 27,724 | $9.00 |
| 2008-07-31 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 201,648 | $9.00 |
| 2008-07-31 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 1,539 | $9.00 |
| 2008-07-31 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 864,092 | $9.00 |
| 2008-07-31 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 4,997 | $9.00 |
| 2008-05-22 | BAKER, JULIAN | Director, 10% Owner | ストックオプション | 購入 | 20,000 | $0.00 |
| 2008-05-22 | ARIKO, BARRY A | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2008-05-22 | NIBLACK, JOHN F | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2008-05-22 | BROOKE, PAUL A | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2008-05-22 | DE, SCHUTTER RICHARD U | Director, Chairman | ストックオプション | 購入 | 20,000 | $0.00 |
| 2008-05-22 | WHITFIELD, ROY A | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2008-05-22 | EMMENS, MATTHEW | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2008-02-08 | SCHRECK, PATRICIA A | EVP, General Counsel | ストックオプション | 購入 | 90,335 | $0.00 |
| 2008-02-08 | KELLER, JOHN A | Chief Business Officer | ストックオプション | 購入 | 9,475 | $0.00 |
| 2008-02-08 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | ストックオプション | 購入 | 8,347 | $0.00 |
| 2008-02-08 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | ストックオプション | 購入 | 191,653 | $0.00 |
| 2008-02-08 | METCALF, BRIAN W | Chief Drug Discovery Scientist | ストックオプション | 購入 | 9,665 | $0.00 |
| 2008-02-08 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 購入 | 90,335 | $0.00 |
| 2008-02-08 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 購入 | 9,665 | $0.00 |
| 2008-02-08 | METCALF, BRIAN W | Chief Drug Discovery Scientist | ストックオプション | 購入 | 90,335 | $0.00 |
| 2008-02-08 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 90,335 | $0.00 |
| 2008-02-08 | KELLER, JOHN A | Chief Business Officer | ストックオプション | 購入 | 90,525 | $0.00 |
| 2008-02-08 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 購入 | 8,874 | $0.00 |
| 2008-02-08 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 購入 | 31,126 | $0.00 |
| 2008-02-08 | SCHRECK, PATRICIA A | EVP, General Counsel | ストックオプション | 購入 | 9,665 | $0.00 |
| 2008-02-08 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 9,665 | $0.00 |
| 2008-01-30 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 831,000 | $ |
| 2008-01-30 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 355,000 | $ |
| 2008-01-30 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 17,000 | $ |
| 2008-01-30 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 566,000 | $ |
| 2008-01-30 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 26,000 | $ |
| 2008-01-30 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 48,000 | $ |
| 2008-01-30 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 2,000 | $ |
| 2008-01-30 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 17,781,000 | $ |
| 2008-01-29 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 4,000 | $ |
| 2008-01-29 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 117,000 | $ |
| 2008-01-29 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 3,000 | $ |
| 2008-01-22 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 1 | $10.62 |
| 2008-01-22 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 7 | $10.62 |
| 2008-01-22 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 223 | $10.62 |
| 2008-01-22 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 65 | $10.62 |
| 2008-01-22 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 4 | $10.62 |
| 2008-01-14 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 94 | $10.99 |
| 2008-01-14 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 1,101 | $10.99 |
| 2008-01-14 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 13,675 | $10.99 |
| 2008-01-14 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 723 | $10.99 |
| 2008-01-14 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 34,621 | $10.99 |
| 2008-01-11 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 12,120 | $10.94 |
| 2008-01-11 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 641 | $10.94 |
| 2008-01-11 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 973 | $10.94 |
| 2008-01-11 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 30,682 | $10.94 |
| 2008-01-11 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 84 | $10.94 |
| 2008-01-10 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 40 | $11.01 |
| 2008-01-10 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 490 | $11.01 |
| 2008-01-10 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 26 | $11.01 |
| 2008-01-10 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 3 | $11.01 |
| 2008-01-10 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 1,241 | $11.01 |
| 2008-01-09 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 2,878 | $10.94 |
| 2008-01-09 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 90,591 | $10.94 |
| 2008-01-09 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 35,783 | $10.94 |
| 2008-01-09 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 247 | $10.94 |
| 2008-01-09 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 1,892 | $10.94 |
| 2008-01-08 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 9,576 | $10.89 |
| 2008-01-08 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 458,644 | $10.89 |
| 2008-01-08 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 24,154 | $10.00 |
| 2008-01-08 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 14,569 | $10.89 |
| 2008-01-08 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 768 | $10.00 |
| 2008-01-08 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 181,168 | $10.89 |
| 2008-01-08 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 9,541 | $10.00 |
| 2008-01-08 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 504 | $10.00 |
| 2008-01-08 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 1,252 | $10.89 |
| 2008-01-08 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 66 | $10.00 |
| 2008-01-07 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 83,853 | $9.48 |
| 2008-01-07 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 212,282 | $9.48 |
| 2008-01-07 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 4,432 | $9.48 |
| 2008-01-07 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 6,744 | $9.48 |
| 2008-01-07 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 579 | $9.48 |
| 2008-01-04 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 118,009 | $9.47 |
| 2008-01-04 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 815 | $9.47 |
| 2008-01-04 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 6,237 | $9.47 |
| 2008-01-04 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 298,752 | $9.47 |
| 2008-01-04 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 9,492 | $9.47 |
| 2007-12-19 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 243 | $10.61 |
| 2007-12-19 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 1,862 | $10.61 |
| 2007-12-19 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 89,198 | $10.61 |
| 2007-12-19 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 2,834 | $10.61 |
| 2007-12-19 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 35,234 | $10.61 |
| 2007-12-18 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 147 | $10.58 |
| 2007-12-18 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 53,824 | $10.58 |
| 2007-12-18 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 1,710 | $10.58 |
| 2007-12-18 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 21,261 | $10.58 |
| 2007-12-18 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 1,124 | $10.58 |
| 2007-12-17 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 1,974 | $10.60 |
| 2007-12-17 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 94,565 | $10.60 |
| 2007-12-17 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 37,354 | $10.60 |
| 2007-12-17 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 3,005 | $10.60 |
| 2007-12-17 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 258 | $10.60 |
| 2007-12-12 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 67,353 | $10.38 |
| 2007-12-12 | BAKER, BIOTECH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 67,353 | $10.38 |
| 2007-12-12 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 465 | $10.38 |
| 2007-12-12 | BAKER, / TISCH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 3,560 | $10.38 |
| 2007-12-12 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 5,418 | $10.38 |
| 2007-12-12 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 170,512 | $10.38 |
| 2007-12-12 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 3,560 | $10.38 |
| 2007-12-11 | BAKER, / TISCH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 1,392 | $9.85 |
| 2007-12-11 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 2,788 | $9.87 |
| 2007-12-11 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 182 | $9.85 |
| 2007-12-11 | BAKER, BIOTECH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 34,670 | $9.87 |
| 2007-12-11 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 26,336 | $9.85 |
| 2007-12-11 | BAKER, BIOTECH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 26,336 | $9.85 |
| 2007-12-11 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 87,770 | $9.87 |
| 2007-12-11 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 66,672 | $9.85 |
| 2007-12-11 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 1,832 | $9.87 |
| 2007-12-11 | BAKER, / TISCH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 1,832 | $9.87 |
| 2007-12-11 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 240 | $9.87 |
| 2007-12-11 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 2,118 | $9.85 |
| 2007-12-11 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 1,392 | $9.85 |
| 2007-12-11 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 34,670 | $9.87 |
| 2007-12-10 | BAKER, / TISCH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 2,265 | $9.54 |
| 2007-12-10 | BAKER, BIOTECH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 42,843 | $9.54 |
| 2007-12-10 | BAKER, / TISCH CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 2,265 | $9.54 |
| 2007-12-10 | BAKER, BROS. CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 296 | $9.54 |
| 2007-12-10 | 14159, CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 3,445 | $9.54 |
| 2007-12-10 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director, 10% Owner | 普通株式 | 購入 | 108,461 | $9.54 |
| 2007-12-10 | BAKER, BIOTECH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 42,843 | $9.54 |
| 2007-12-04 | BAKER, BIOTECH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 19,593 | $8.98 |
| 2007-12-04 | BAKER, BROS. CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 153 | $8.98 |
| 2007-12-04 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 57,303 | $8.98 |
| 2007-12-04 | 14159, CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 1,812 | $8.98 |
| 2007-12-04 | BAKER, / TISCH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 1,139 | $8.98 |
| 2007-12-03 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 23,842 | $8.96 |
| 2007-12-03 | 14159, CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 753 | $8.96 |
| 2007-12-03 | BAKER, BIOTECH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 4,241 | $8.96 |
| 2007-12-03 | BAKER, BROS. CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 64 | $8.96 |
| 2007-11-30 | 14159, CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 1,734 | $8.59 |
| 2007-11-30 | BAKER, BIOTECH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 9,764 | $8.59 |
| 2007-11-30 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 54,899 | $8.59 |
| 2007-11-30 | BAKER, BROS. CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 147 | $8.59 |
| 2007-11-29 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 17,572 | $8.58 |
| 2007-11-29 | BAKER, BROS. CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 47 | $8.58 |
| 2007-11-29 | 14159, CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 556 | $8.58 |
| 2007-11-29 | BAKER, BIOTECH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 3,125 | $8.58 |
| 2007-11-28 | 14159, CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 4,042 | $8.40 |
| 2007-11-28 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 127,875 | $8.40 |
| 2007-11-28 | BAKER, BROS. CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 342 | $8.40 |
| 2007-11-28 | BAKER, BIOTECH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 22,741 | $8.40 |
| 2007-11-27 | BAKER, BIOTECH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 35,237 | $8.00 |
| 2007-11-27 | 14159, CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 6,262 | $8.00 |
| 2007-11-27 | BAKER, BROS. CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 530 | $8.00 |
| 2007-11-27 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 198,138 | $8.00 |
| 2007-11-27 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 3,654 | $ |
| 2007-11-26 | BAKER, BIOTECH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 15,282 | $7.94 |
| 2007-11-26 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 85,927 | $7.94 |
| 2007-11-26 | 14159, CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 2,715 | $7.94 |
| 2007-11-26 | BAKER, BROS. CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 230 | $7.94 |
| 2007-11-21 | 14159, CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 1,770 | $8.12 |
| 2007-11-21 | BAKER, BIOTECH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 9,961 | $8.12 |
| 2007-11-21 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 56,010 | $8.12 |
| 2007-11-21 | BAKER, BROS. CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 150 | $8.12 |
| 2007-11-20 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 78,415 | $8.10 |
| 2007-11-20 | BAKER, BIOTECH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 13,945 | $8.10 |
| 2007-11-20 | 14159, CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 2,478 | $8.10 |
| 2007-11-20 | BAKER, BROS. CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 210 | $8.10 |
| 2007-11-19 | BAKER, BROS. CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 387 | $8.22 |
| 2007-11-19 | BAKER, BIOTECH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 46,836 | $8.22 |
| 2007-11-19 | BAKER, / TISCH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 318 | $8.22 |
| 2007-11-19 | 14159, CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 4,566 | $8.22 |
| 2007-11-19 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 144,486 | $8.22 |
| 2007-11-16 | BAKER, BROS. CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 274 | $8.30 |
| 2007-11-16 | BAKER, / TISCH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 225 | $8.30 |
| 2007-11-16 | 14159, CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 3,232 | $8.30 |
| 2007-11-16 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 102,285 | $8.30 |
| 2007-11-16 | BAKER, BIOTECH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 33,157 | $8.30 |
| 2007-11-15 | BAKER, / TISCH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 381 | $8.62 |
| 2007-11-15 | 14159, CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 5 | $8.63 |
| 2007-11-15 | 14159, CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 3,421 | $8.62 |
| 2007-11-15 | BAKER, BIOTECH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 42,783 | $8.62 |
| 2007-11-15 | BAKER, BIOTECH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 60 | $8.63 |
| 2007-11-15 | BAKER, BROS. CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 290 | $8.62 |
| 2007-11-15 | BAKER, / TISCH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 1 | $8.63 |
| 2007-11-15 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 108,254 | $8.62 |
| 2007-11-15 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 151 | $8.63 |
| 2007-11-14 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 1,793 | $8.54 |
| 2007-11-14 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 124,973 | $8.53 |
| 2007-11-14 | BAKER, BIOTECH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 709 | $8.54 |
| 2007-11-14 | BAKER, BIOTECH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 49,390 | $8.53 |
| 2007-11-14 | BAKER, BROS. CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 5 | $8.54 |
| 2007-11-14 | BAKER, BROS. CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 335 | $8.53 |
| 2007-11-14 | BAKER, / TISCH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 6 | $8.54 |
| 2007-11-14 | BAKER, / TISCH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 440 | $8.53 |
| 2007-11-14 | 14159, CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 3,949 | $8.53 |
| 2007-11-14 | 14159, CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 57 | $8.54 |
| 2007-11-13 | BAKER, BROS. CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 53 | $8.26 |
| 2007-11-13 | DE, SCHUTTER RICHARD U | Director, Chairman | 普通株式 | 購入 | 20,000 | $3.86 |
| 2007-11-13 | DE, SCHUTTER RICHARD U | Director, Chairman | 普通株式 | 購入 | 25,000 | $4.44 |
| 2007-11-13 | BAKER, BROS. CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 234 | $8.25 |
| 2007-11-13 | 14159, CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 739 | $8.30 |
| 2007-11-13 | BAKER, / TISCH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 82 | $8.30 |
| 2007-11-13 | BAKER, / TISCH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 51 | $8.22 |
| 2007-11-13 | 14159, CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 457 | $8.22 |
| 2007-11-13 | 14159, CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 627 | $8.26 |
| 2007-11-13 | 14159, CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 2,760 | $8.25 |
| 2007-11-13 | BAKER, / TISCH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 308 | $8.25 |
| 2007-11-13 | BAKER, / TISCH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 70 | $8.26 |
| 2007-11-13 | BAKER, BIOTECH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 9,239 | $8.30 |
| 2007-11-13 | BAKER, BIOTECH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 5,727 | $8.22 |
| 2007-11-13 | BAKER, BIOTECH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 7,843 | $8.26 |
| 2007-11-13 | BAKER, BIOTECH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 34,518 | $8.25 |
| 2007-11-13 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 23,377 | $8.30 |
| 2007-11-13 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 14,490 | $8.22 |
| 2007-11-13 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 19,844 | $8.26 |
| 2007-11-13 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 87,343 | $8.25 |
| 2007-11-13 | BAKER, BROS. CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 63 | $8.30 |
| 2007-11-13 | BAKER, BROS. CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 39 | $8.22 |
| 2007-11-13 | DE, SCHUTTER RICHARD U | Director, Chairman | ストックオプション | 売却 | 25,000 | $0.00 |
| 2007-11-13 | DE, SCHUTTER RICHARD U | Director, Chairman | ストックオプション | 売却 | 20,000 | $0.00 |
| 2007-11-12 | 14159, CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 677 | $8.23 |
| 2007-11-12 | 14159, CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 4,455 | $8.30 |
| 2007-11-12 | 14159, CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 5,458 | $8.20 |
| 2007-11-12 | 14159, CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 353 | $8.00 |
| 2007-11-12 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 140,951 | $8.30 |
| 2007-11-12 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 172,694 | $8.20 |
| 2007-11-12 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 21,397 | $8.23 |
| 2007-11-12 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 11,165 | $8.00 |
| 2007-11-12 | BAKER, / TISCH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 496 | $8.30 |
| 2007-11-12 | BAKER, / TISCH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 608 | $8.20 |
| 2007-11-12 | BAKER, / TISCH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 75 | $8.23 |
| 2007-11-12 | BAKER, / TISCH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 39 | $8.00 |
| 2007-11-12 | BAKER, BIOTECH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 55,704 | $8.30 |
| 2007-11-12 | BAKER, BIOTECH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 68,249 | $8.20 |
| 2007-11-12 | BAKER, BIOTECH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 8,456 | $8.23 |
| 2007-11-12 | BAKER, BIOTECH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 4,413 | $8.00 |
| 2007-11-12 | BAKER, BROS. CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 377 | $8.30 |
| 2007-11-12 | BAKER, BROS. CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 462 | $8.20 |
| 2007-11-12 | BAKER, BROS. CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 57 | $8.23 |
| 2007-11-12 | BAKER, BROS. CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 30 | $8.00 |
| 2007-11-09 | BAKER, BROS. CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 532 | $7.70 |
| 2007-11-09 | BAKER, BIOTECH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 1,434 | $7.90 |
| 2007-11-09 | BAKER, / TISCH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 700 | $7.70 |
| 2007-11-09 | BAKER, / TISCH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 13 | $7.90 |
| 2007-11-09 | 14159, CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 6,286 | $7.70 |
| 2007-11-09 | 14159, CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 114 | $7.90 |
| 2007-11-09 | BAKER, BIOTECH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 78,599 | $7.70 |
| 2007-11-09 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 3,629 | $7.90 |
| 2007-11-09 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 198,883 | $7.70 |
| 2007-11-09 | BAKER, BROS. CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 10 | $7.90 |
| 2007-08-17 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 普通株式 | 購入 | 4,600 | $5.48 |
| 2007-08-17 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 普通株式 | 購入 | 3,000 | $5.45 |
| 2007-08-17 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 普通株式 | 購入 | 2,000 | $5.46 |
| 2007-08-17 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 普通株式 | 購入 | 5,000 | $5.47 |
| 2007-08-17 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 普通株式 | 購入 | 400 | $5.48 |
| 2007-08-17 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 普通株式 | 購入 | 1,665 | $5.49 |
| 2007-08-03 | 14159, CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 5,366 | $4.83 |
| 2007-08-03 | BAKER, BIOTECH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 64,003 | $4.83 |
| 2007-08-03 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 168,797 | $4.83 |
| 2007-08-03 | BAKER, BROS. CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 430 | $4.83 |
| 2007-08-02 | 14159, CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 1,463 | $4.99 |
| 2007-08-02 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 46,012 | $4.99 |
| 2007-08-02 | BAKER, BIOTECH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 17,446 | $4.99 |
| 2007-08-02 | BAKER, BROS. CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 117 | $4.99 |
| 2007-08-01 | BAKER, BROS. CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 604 | $4.95 |
| 2007-08-01 | 14159, CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 7,536 | $4.95 |
| 2007-08-01 | BAKER, BROTHERS LIFE SCIENCES CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 237,052 | $4.95 |
| 2007-08-01 | BAKER, BIOTECH CAPITAL (GP), LLC | Director | 普通株式 | 購入 | 89,883 | $4.95 |
| 2007-05-22 | DE, SCHUTTER RICHARD U | Director, Chairman | ストックオプション | 購入 | 20,000 | $0.00 |
| 2007-05-22 | ARIKO, BARRY A | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2007-05-22 | NIBLACK, JOHN F | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2007-05-22 | BAKER, JULIAN | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2007-05-22 | EMMENS, MATTHEW | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2007-05-22 | BROOKE, PAUL A | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2007-05-22 | WHITFIELD, ROY A | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2007-02-12 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 購入 | 5,556 | $0.00 |
| 2007-02-12 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | ストックオプション | 購入 | 10,895 | $0.00 |
| 2007-02-12 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | ストックオプション | 購入 | 189,105 | $0.00 |
| 2007-02-12 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 購入 | 94,444 | $0.00 |
| 2007-02-12 | SCHRECK, PATRICIA A | EVP, General Counsel | ストックオプション | 購入 | 5,556 | $0.00 |
| 2007-02-12 | SCHRECK, PATRICIA A | EVP, General Counsel | ストックオプション | 購入 | 94,444 | $0.00 |
| 2007-02-12 | METCALF, BRIAN W | Chief Drug Discovery Scientist | ストックオプション | 購入 | 94,444 | $0.00 |
| 2007-02-12 | METCALF, BRIAN W | Chief Drug Discovery Scientist | ストックオプション | 購入 | 5,556 | $0.00 |
| 2007-02-12 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 購入 | 35,700 | $0.00 |
| 2007-02-12 | CHARDONNET, LAURENT | Vice President and Treasurer | ストックオプション | 購入 | 4,300 | $0.00 |
| 2007-02-12 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 94,444 | $0.00 |
| 2007-02-12 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 5,556 | $0.00 |
| 2007-02-12 | KELLER, JOHN A | Chief Business Officer | ストックオプション | 購入 | 5,556 | $0.00 |
| 2007-02-12 | KELLER, JOHN A | Chief Business Officer | ストックオプション | 購入 | 94,444 | $0.00 |
| 2007-01-31 | BAKER, BROS. CAPITAL (GP), LLC | Director | 普通株式 | 売却 | 11,206 | $0.00 |
| 2007-01-31 | BAKER, BROS. CAPITAL (GP), LLC | Director | 普通株式 | 売却 | 28,000 | $0.00 |
| 2006-12-21 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 1,800 | $ |
| 2006-10-16 | DE, SCHUTTER RICHARD U | Director, Chairman | 普通株式 | 売却 | $100,000.00 | |
| 2006-10-11 | BAKER, JULIAN | Director | 普通株式 | 売却 | 24,000 | $ |
| 2006-10-11 | BAKER, JULIAN | Director | 普通株式 | 売却 | 750,000 | $ |
| 2006-05-23 | DE, SCHUTTER RICHARD U | Director, Chairman | ストックオプション | 購入 | 20,000 | $0.00 |
| 2006-05-23 | WHITFIELD, ROY A | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2006-05-23 | NIBLACK, JOHN F | Director | ストックオプション | 購入 | 35,000 | $0.00 |
| 2006-05-23 | EMMENS, MATTHEW | Director | ストックオプション | 購入 | 35,000 | $0.00 |
| 2006-05-23 | BAKER, JULIAN | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2006-05-23 | ARIKO, BARRY A | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2006-05-23 | BROOKE, PAUL A | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2006-04-25 | BAKER, JULIAN | Director | 普通株式 | 購入 | 1,203,937 | $0.00 |
| 2006-04-25 | BAKER, JULIAN | Director | 普通株式 | 売却 | 7,207,000 | $0.00 |
| 2006-04-25 | BAKER, JULIAN | Director | 普通株式 | 売却 | 444,000 | $0.00 |
| 2006-04-25 | BAKER, JULIAN | Director | 普通株式 | 売却 | 516,000 | $0.00 |
| 2006-04-25 | BAKER, JULIAN | Director | 普通株式 | 購入 | 8,167,000 | $0.00 |
| 2006-04-25 | BAKER, JULIAN | Director | 普通株式 | 売却 | 1,105,590 | $0.00 |
| 2006-04-25 | BAKER, JULIAN | Director | 普通株式 | 売却 | 84,112 | $0.00 |
| 2006-04-25 | BAKER, JULIAN | Director | 普通株式 | 売却 | 14,235 | $0.00 |
| 2006-04-17 | METCALF, BRIAN W | Chief Drug Discovery Scientist | 普通株式 | 購入 | 3,368 | $3.88 |
| 2006-04-17 | METCALF, BRIAN W | Chief Drug Discovery Scientist | 普通株式 | 購入 | 1,632 | $3.89 |
| 2006-04-06 | SWAIN, PAULA J | EVP, Human Resources | 普通株式 | 購入 | 3,000 | $3.65 |
| 2006-04-04 | HASTINGS, DAVID C | Chief Financial Officer | 普通株式 | 購入 | 2,500 | $3.60 |
| 2006-04-04 | SCHRECK, PATRICIA A | EVP, General Counsel | 普通株式 | 購入 | 2,000 | $3.59 |
| 2006-04-04 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 普通株式 | 購入 | 5,500 | $3.56 |
| 2006-01-13 | KELLER, JOHN A | Chief Business Officer | ストックオプション | 購入 | 102,445 | $0.00 |
| 2006-01-13 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 購入 | 83,375 | $0.00 |
| 2006-01-13 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | ストックオプション | 購入 | 185,753 | $0.00 |
| 2006-01-13 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | ストックオプション | 購入 | 14,247 | $0.00 |
| 2006-01-13 | METCALF, BRIAN W | Chief Drug Discovery Scientist | ストックオプション | 購入 | 82,688 | $0.00 |
| 2006-01-13 | METCALF, BRIAN W | Chief Drug Discovery Scientist | ストックオプション | 購入 | 17,312 | $0.00 |
| 2006-01-13 | CHARDONNET, LAURENT | VP Finance and Treasurer | ストックオプション | 購入 | 29,165 | $0.00 |
| 2006-01-13 | CHARDONNET, LAURENT | VP Finance and Treasurer | ストックオプション | 購入 | 10,835 | $0.00 |
| 2006-01-13 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 16,967 | $0.00 |
| 2006-01-13 | SWAIN, PAULA J | EVP, Human Resources | ストックオプション | 購入 | 83,033 | $0.00 |
| 2006-01-13 | SCHRECK, PATRICIA A | EVP, General Counsel | ストックオプション | 購入 | 16,796 | $0.00 |
| 2006-01-13 | SCHRECK, PATRICIA A | EVP, General Counsel | ストックオプション | 購入 | 83,204 | $0.00 |
| 2006-01-13 | KELLER, JOHN A | Chief Business Officer | ストックオプション | 購入 | 17,555 | $0.00 |
| 2006-01-13 | HASTINGS, DAVID C | Chief Financial Officer | ストックオプション | 購入 | 16,625 | $0.00 |
| 2005-12-22 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 4,300 | $ |
| 2005-11-26 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 普通株式 | 購入 | 50,000 | $ |
| 2005-11-26 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 譲渡制限付株式ユニット | 売却 | 50,000 | $ |
| 2005-08-23 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 普通株式 | 購入 | 1,300 | $7.25 |
| 2005-08-23 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 普通株式 | 購入 | 1,200 | $7.24 |
| 2005-08-23 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 普通株式 | 購入 | 200 | $7.23 |
| 2005-06-22 | BAKER, JULIAN | Director | 普通株式 | 売却 | 4,986,000 | $ |
| 2005-06-01 | WHITFIELD, ROY A | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2005-06-01 | BAKER, JULIAN | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2005-06-01 | ARIKO, BARRY A | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2005-06-01 | CRAVES, FRED B | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2005-06-01 | BROOKE, PAUL A | Director | ストックオプション | 購入 | 20,000 | $0.00 |
| 2005-06-01 | DE, SCHUTTER RICHARD U | Director, Chairman | ストックオプション | 購入 | 20,000 | $0.00 |
| 2005-03-10 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 普通株式 | 購入 | 50,000 | $0.00 |
| 2005-03-10 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 譲渡制限付株式ユニット | 売却 | 50,000 | $0.00 |
| 2005-03-10 | WHITFIELD, ROY A | Director | 譲渡制限付株式ユニット | 購入 | 50,000 | $0.00 |
| 2005-03-10 | WHITFIELD, ROY A | Director | 普通株式 | 売却 | 18,737 | $7.24 |
| 2005-03-10 | WHITFIELD, ROY A | Director | 普通株式 | 購入 | 50,000 | $0.00 |
| 2005-03-09 | DE, SCHUTTER RICHARD U | Director | 普通株式 | 購入 | 20,000 | $7.05 |
| 2005-01-19 | HURLEY, SCOTT W | VP/Corp Controller & Treasurer | ストックオプション | 購入 | 27,251 | $0.00 |
| 2005-01-19 | HURLEY, SCOTT W | VP/Corp Controller & Treasurer | ストックオプション | 購入 | 12,749 | $0.00 |
| 2005-01-18 | HASTINGS, DAVID C | Exec VP & CFO | ストックオプション | 購入 | 13,035 | $0.00 |
| 2005-01-18 | HASTINGS, DAVID C | Exec VP & CFO | ストックオプション | 購入 | 96,965 | $0.00 |
| 2005-01-18 | SWAIN, PAULA J | Exec VP, Human Resources | ストックオプション | 購入 | 88,881 | $0.00 |
| 2005-01-18 | SCHRECK, PATRICIA A | EVP and General Counsel | ストックオプション | 購入 | 13,311 | $0.00 |
| 2005-01-18 | METCALF, BRIAN W | EVP/Chief Drug Dscvy Scientist | ストックオプション | 購入 | 10,454 | $0.00 |
| 2005-01-18 | METCALF, BRIAN W | EVP/Chief Drug Dscvy Scientist | ストックオプション | 購入 | 79,546 | $0.00 |
| 2005-01-18 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | ストックオプション | 購入 | 6,480 | $0.00 |
| 2005-01-18 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | ストックオプション | 購入 | 193,520 | $0.00 |
| 2005-01-18 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | ストックオプション | 購入 | 39,166 | $0.00 |
| 2005-01-18 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | ストックオプション | 購入 | 834 | $0.00 |
| 2005-01-18 | SWAIN, PAULA J | Exec VP, Human Resources | ストックオプション | 購入 | 11,119 | $0.00 |
| 2005-01-18 | SCHRECK, PATRICIA A | EVP and General Counsel | ストックオプション | 購入 | 91,689 | $0.00 |
| 2005-01-18 | KELLER, JOHN A | Exec VP & Chief Bus Officer | ストックオプション | 購入 | 11,204 | $0.00 |
| 2005-01-18 | KELLER, JOHN A | Exec VP & Chief Bus Officer | ストックオプション | 購入 | 83,796 | $0.00 |
| 2004-11-12 | BAKER, JULIAN | Director | 普通株式 | 購入 | $ | |
| 2004-11-01 | BAKER, JULIAN | Director | 普通株式 | 購入 | 94,674 | $9.75 |
| 2004-11-01 | BAKER, JULIAN | Director | 普通株式 | 購入 | 14,235 | $9.75 |
| 2004-11-01 | BAKER, JULIAN | Director | 普通株式 | 購入 | 74,190 | $9.75 |
| 2004-11-01 | BAKER, JULIAN | Director | 普通株式 | 購入 | 11,912 | $9.75 |
| 2004-11-01 | BAKER, JULIAN | Director | 普通株式 | 購入 | 86,383 | $9.75 |
| 2004-11-01 | BAKER, JULIAN | Director | 普通株式 | 購入 | 18,606 | $9.75 |
| 2004-09-09 | BROOKE, PAUL A | Director | 普通株式 | 購入 | 100,000 | $7.74 |
| 2004-08-16 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 普通株式 | 購入 | 1,927 | $5.63 |
| 2004-08-16 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | 普通株式 | 購入 | 1,573 | $5.60 |
| 2004-08-12 | TISCH, DANIEL R | 10% Owner | 普通株式 | 購入 | 255,750 | $5.50 |
| 2004-08-12 | TISCH, DANIEL R | No longer 10% owner. | 普通株式 | 購入 | 255,750 | $5.50 |
| 2004-08-12 | TISCH, THOMAS J | 10% Owner | 普通株式 | 購入 | 255,750 | $5.50 |
| 2004-08-12 | TISCH, JAMES S | No longer 10% owner. | 普通株式 | 購入 | 255,750 | $5.50 |
| 2004-08-12 | TISCH, THOMAS J | No longer 10% owner. | 普通株式 | 購入 | 255,750 | $5.50 |
| 2004-08-12 | TISCH, ANDREW H | No longer 10% owner. | 普通株式 | 購入 | 255,750 | $5.50 |
| 2004-08-12 | TISCH, JAMES S | 10% Owner | 普通株式 | 購入 | 255,750 | $5.50 |
| 2004-08-12 | TISCH, ANDREW H | 10% Owner | 普通株式 | 購入 | 255,750 | $5.50 |
| 2004-05-25 | BROOKE, PAUL A | Director | ストックオプション | 購入 | 25,000 | $0.00 |
| 2004-05-25 | BAKER, JULIAN | Director, 10% Owner | ストックオプション | 購入 | 10,000 | $0.00 |
| 2004-05-25 | ARIKO, BARRY A | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2004-05-25 | BROOKE, PAUL A | Director | ストックオプション | 購入 | 25,000 | $0.00 |
| 2004-05-25 | WHITFIELD, ROY A | Director, Chairman | ストックオプション | 購入 | 10,000 | $0.00 |
| 2004-05-25 | CRAVES, FRED B | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2004-05-25 | DE, SCHUTTER RICHARD U | Director | ストックオプション | 購入 | 50,000 | $0.00 |
| 2004-05-25 | CRAVES, FRED B | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2004-05-25 | WHITFIELD, ROY A | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2004-05-25 | ARIKO, BARRY A | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2004-04-21 | CRAVES, FRED B | Director | 普通株式 | 購入 | 56,793 | $0.00 |
| 2004-03-30 | SAXE, JON S | Director | ストックオプション | 売却 | 20,000 | $0.00 |
| 2004-03-30 | SAXE, JON S | Director | 普通株式 | 購入 | 20,000 | $2.78 |
| 2004-02-27 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | ストックオプション | 購入 | 43,125 | $0.00 |
| 2004-02-27 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | ストックオプション | 購入 | 30,441 | $0.00 |
| 2004-02-27 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | ストックオプション | 購入 | 1,875 | $0.00 |
| 2004-02-27 | FRIEDMAN, PAUL A | Director, Chief Executive Officer | ストックオプション | 購入 | 144,559 | $0.00 |
| 2004-02-19 | BAKER, BIOTECH CAPITAL GP LLC | 10% Owner | 普通株式 | 購入 | $ | |
| 2004-02-19 | BAKER, BIOTECH CAPITAL GP LLC | 10% Owner | 普通株式 | 購入 | $ | |
| 2004-02-19 | BAKER, BIOTECH CAPITAL II GP LLC | 10% Owner | 普通株式 | 購入 | $ | |
| 2004-02-13 | SWAIN, PAULA J | Executive VP, Human Resources | ストックオプション | 購入 | 34,750 | $0.00 |
| 2004-02-13 | METCALF, BRIAN W | EVP/Chief Drug DiscvyScientist | ストックオプション | 購入 | 18,208 | $0.00 |
| 2004-02-13 | METCALF, BRIAN W | EVP/Chief Drug DiscvyScientist | ストックオプション | 購入 | 48,792 | $0.00 |
| 2004-02-13 | SWAIN, PAULA J | Executive VP, Human Resources | ストックオプション | 購入 | 20,250 | $0.00 |
| 2004-02-13 | KELLER, JOHN A | Exec VP & Chief Bus Officer | ストックオプション | 購入 | 2,084 | $0.00 |
| 2004-02-13 | KELLER, JOHN A | Exec VP & Chief Bus Officer | ストックオプション | 購入 | 47,916 | $0.00 |
| 2004-02-13 | HASTINGS, DAVID C | Exec VP & CFO | ストックオプション | 購入 | 417 | $0.00 |
| 2004-02-13 | HASTINGS, DAVID C | Exec VP & CFO | ストックオプション | 購入 | 9,583 | $0.00 |
| 2004-02-12 | TISCH, ANDREW H | 10% Owner | 普通株式 | 売却 | $ | |
| 2004-02-12 | TISCH, JAMES S | 10% Owner | 普通株式 | 売却 | $ | |
| 2004-02-12 | TISCH, DANIEL R | 10% Owner | 普通株式 | 売却 | $ | |
| 2004-02-12 | TISCH, THOMAS J | 10% Owner | 普通株式 | 売却 | $ | |
| 2004-02-11 | TISCH, JAMES S | 10% Owner | 普通株式 | 売却 | $ | |
| 2004-02-11 | TISCH, THOMAS J | 10% Owner | 普通株式 | 売却 | $ | |
| 2004-02-11 | TISCH, DANIEL R | 10% Owner | 普通株式 | 売却 | $ | |
| 2004-02-11 | TISCH, DANIEL R | 10% Owner | 普通株式 | 売却 | $ | |
| 2004-02-11 | TISCH, ANDREW H | 10% Owner | 普通株式 | 売却 | $ | |
| 2004-02-11 | DAMIAL, FOUNDATION INC | 10% Owner | 普通株式 | 売却 | $ | |
| 2004-02-10 | DAMIAL, FOUNDATION INC | 10% Owner | 普通株式 | 売却 | $ | |
| 2004-02-10 | TISCH, JAMES S | 10% Owner | 普通株式 | 売却 | $ | |
| 2004-02-10 | TISCH, THOMAS J | 10% Owner | 普通株式 | 売却 | $ | |
| 2004-02-10 | TISCH, DANIEL R | 10% Owner | 普通株式 | 売却 | $ | |
| 2004-02-10 | TISCH, ANDREW H | 10% Owner | 普通株式 | 売却 | $ | |
| 2004-02-09 | TISCH, ANDREW H | 10% Owner | 普通株式 | 売却 | $ | |
| 2004-02-09 | TISCH, DANIEL R | 10% Owner | 普通株式 | 売却 | $ | |
| 2004-02-09 | TISCH, THOMAS J | 10% Owner | 普通株式 | 売却 | $ | |
| 2004-02-09 | TISCH, JAMES S | 10% Owner | 普通株式 | 売却 | $ | |
| 2004-02-03 | TISCH, THOMAS J | 10% Owner | 普通株式 | 売却 | $ |
売上・収益性
売上高（直近12ヶ月）
$514,124万ドル
一株あたり売上高（直近12ヶ月）
$26.34
売上総利益（直近12ヶ月）
$271,896万ドル
営業利益（EBITDA：減価償却前）
$143,977万ドル
利益率
25.0%
営業利益率（直近12ヶ月）
25.6%
配当・収入
配当金額（1株あたり）
$None
配当利回り
0%
支払日
None
権利落ち日
None
バリュエーション指標
株価収益率（PER）
14.99倍
実績PER
14.99倍
予想PER
13.02倍
株価収益成長率（PEG）
0.351
株価売上高倍率（直近12ヶ月）
3.719倍
株価純資産倍率 (PBR)
3.734倍
1株当たり純資産（BPS）
$26.04
企業価値倍率（EV）
EV/売上高倍率
3.065倍
EV/EBITDA倍率
8.95倍
投資リターン
総資産利益率（直近12ヶ月）
13.6%
自己資本利益率（直近12ヶ月）
29.9%
リターン分析
| 日数 | リターンレンジ | リターン中央値 | 累積リターン | 分散（バリアンス） | 標準偏差 | 最大下落率 | 最大下落期間 | SPYとの相関係数 | ||
|---|---|---|---|---|---|---|---|---|---|---|
| 15日間 | -1.2334% | 2.3482% | -0.175% | 3.1662% | 0.00018033778589722163 | 0.01342899050179207 | -2.335% | 5日 | -0.2776336420162573 | |
| 30日間 | -2.3346% | 4.1957% | 0.0329% | 2.4946% | 0.00027137355940191405 | 0.016473419784668698 | -2.6896% | 4日 | -0.12288751044671573 | |
| 90日間 | -8.2363% | 5.4788% | 0.0463% | -9.4261% | 0.00038366666887164894 | 0.01958741097929098 | -9.3461% | 2日 | -0.09490073547429975 |
損益計算書
会計期末日
2025-12-31
報告通貨
USD
売上高・粗利益
売上原価
営業経費
営業利益・税引前指標
売上高
$5,141,242,000
粗利益
$4,702,526,000
売上コスト
$438,716,000
商品・サービス原価
$438,716,000
販売管理費
$1,376,200,000
研究開発
$1,983,566,000
運営コスト
$3,359,772,000
減価償却
$None
減価償却・償却費
$93,286,000
営業利益
$1,342,754,000
営業利益EBIT
$1,666,879,000
償却前営業利益EBITA
$1,760,165,000
税引前利益
$1,664,451,000
利息・投資・その他営業外項目
税金関連
当期純・包括利益
純投資収益
$None
純金利収入
$103,172,000
利息収入
$105,600,000
金利コスト
$2,428,000
利息・債務コスト
$None
非利息収益
$None
営業外収益（その他）
$None
法人税等
$377,801,000
継続事業純利益
$1,286,650,000
純利益
$1,286,650,000
税引後包括利益
$None
貸借対照表
会計期末日
2025-12-31
報告通貨
USD
総資産
$6,957,973,000
現金及び現金同等物
$3,097,817,000
現金及び短期投資
$3,097,817,000
短期投資
$482,787,000
在庫資産
$101,060,000
流動売掛金（純額）
$1,024,406,999
その他流動資産
$317,831,000
流動資産合計
$5,023,902,000
有形固定資産
$None
減価償却累計額（PPE）
$None
無形資産
$117,131,000
無形資産（のれん除く）
$117,131,000
のれん（無形資産）
$133,000,000
投資
$None
長期投資
$47,991,000
その他固定資産
$None
固定資産合計
$1,523,830,000
総負債
$1,803,373,000
買掛金（短期）
$209,938,000
前受金
$None
流動債務
$None
短期借入金
$10,213,000
固定長期負債
$None
その他流動負債
$1,295,019,000
流動負債合計
$1,515,170,000
リース債務
$40,412,000
長期債務
$None
長期債務（流動外）
$None
短期・長期借入金合計
$69,428,000
その他固定負債
$245,126,000
固定負債合計
$288,203,000
純資産
$5,167,478,000
自己株式（金庫株）
$None
利益剰余金
$213,769,000
普通株式
$198,000
発行済株式数（普通株）
$200,700,000
キャッシュフロー計算書
会計期末日
2025-12-31
報告通貨
USD
損益計算・収益性
営業活動
投資活動
損益
$None
純利益
$1,286,650,000
営業キャッシュフロー
$1,413,498,000
営業活動による支払い
$None
営業活動によるキャッシュフロー
$None
営業活動に関連する負債の増減額
$None
営業活動に関連する資産の増減額
$None
売掛金の増減額
$None
在庫資産の増減額
-$58,513,000
減価償却・減耗費・償却費
$93,286,000
投資活動によるキャッシュフロー
-$102,610,000
設備投資
$58,867,000
財務活動
資金・為替照合
財務活動によるキャッシュフロー
$101,039,000
短期融資回収金
$None
自社株買い支出（普通株）
$None
自社株買い支出（優先株）
$None
自社株買い支出
$None
配当支払い（普通株）
$None
配当支払い（優先株）
$None
配当支払い
$None
資金調達（普通株）
$None
資金調達（優先株）
$None
資金調達（長期債・資本証券）
$None
自社株売却による収益
$None
自社株再取得による収益
-$19,100,000
現金及び現金同等物の増減額
$None
為替レートの変動による増減額
$None
発行済株式数
広告パネル
スポンサー紹介
本物のネイティブ講師による
オンライン英会話DOJO
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