INVA
イノヴィーヴァ
Innoviva Inc
株価・概要
$23.60
-0.32 (-1.3378%)
06:00AM 2026/04/17 (JST)
NASDAQ | USD
52週間レンジ
16.52
25.14
昨夜レンジ
23.28
23.98
前日終値
$23.92
出来高（数量）
768,306
ベータ値
0.489
50日移動平均値
$18.72
200日移動平均値
$18.88
1株あたりの利益（EPS）
1.66
予想PER（株価収益率）
11.71
配当金
$None
配当利回り
0%
インサイダー保有率
1.011%
機関投資家保有率
103.338%
INVA - 会社概要
イノヴィーヴァ社（Innoviva, Inc.）は、カリフォルニア州バーリンゲームに本社を置くバイオ医薬品企業であり、呼吸器疾患のための革新的な治療法の開発と商業化に注力しています。独自の技術と戦略的な提携を通じて、イノヴィーヴァは患者の治療成果を向上させる先進的な治療ソリューションの提供を目指しています。同社は、呼吸器医療における重要な未充足医療ニーズに対応する多様なパイプラインを有しており、患者の生活の質の向上と業界のケア基準の発展に対する強いコミットメントを反映しています。
本社住所
1350 OLD BAYSHORE HIGHWAY, BURLINGAME, CA, UNITED STATES, 94010
企業サイト
https://www.inva.com
会計年度終了
December
最新四半期
2025-09-30
利益・成長性
1株あたりの利益（EPS）
$1.66
希薄化後1株当たり利益EPS（直近12ヶ月）
$1.66
四半期利益成長率（前年比）
5479.0%
四半期売上成長率（前年比）
20.4%
アナリスト予想・評価
目標株価
$36.40
強気
0
買い
4
ホールド
0
売り
1
弱気
0
EPS（1株当たり純利益）
| 7日前 | 30日前 | 60日前 | 90日前 | 予想レンジ | |||
|---|---|---|---|---|---|---|---|
配当履歴
| 権利落ち日 | 配当宣言日 | 権利確定日 | 配当金支払日 | 配当金額 |
|---|---|---|---|---|
| 2015-09-08 | None | None | None | $0.25 |
| 2015-06-10 | None | None | None | $0.25 |
| 2015-03-10 | None | None | None | $0.25 |
| 2014-11-21 | None | None | None | $0.25 |
| 2014-08-26 | None | None | None | $0.25 |
| 2014-06-03 | None | None | None | $5.57 |
株式分割
| 効力発生日 | 分割比率 |
|---|
インサイダーの売却・購入履歴
| 自社株取引日 | 役員・従業員名 | 役員・従業員の役職 | 株式の種類 | 売却／購入 | 株数 | 株価 |
|---|---|---|---|---|---|---|
| 2026-02-20 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 売却 | 2,460 | $23.39 |
| 2026-02-20 | BASSO, STEPHEN | Chief Financial Officer | 普通株式 | 売却 | 1,244 | $23.39 |
| 2026-02-20 | RAIFELD, PAVEL | Director, Chief Executive Officer | 普通株式 | 売却 | 2,986 | $23.39 |
| 2025-11-20 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 売却 | 992 | $21.16 |
| 2025-11-20 | BASSO, STEPHEN | Chief Financial Officer | 普通株式 | 売却 | 237 | $21.16 |
| 2025-11-15 | BASSO, STEPHEN | Chief Financial Officer | 普通株式 | 購入 | 604 | $0.00 |
| 2025-11-03 | BASSO, STEPHEN | Chief Financial Officer | 普通株式 | 購入 | 27,609 | $18.11 |
| 2025-11-03 | RAIFELD, PAVEL | 10% Owner | 普通株式 | 購入 | 110,436 | $18.11 |
| 2025-08-20 | BASSO, STEPHEN | Chief Financial Officer | 普通株式 | 売却 | 237 | $19.95 |
| 2025-08-20 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 売却 | 991 | $19.95 |
| 2025-05-20 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 売却 | 992 | $18.78 |
| 2025-05-20 | BASSO, STEPHEN | Chief Financial Officer | 普通株式 | 売却 | 237 | $18.78 |
| 2025-05-19 | HAIMOVITZ, JULES | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2025-05-19 | SMALL, DEREK A | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2025-05-19 | DIPAOLO, MARK | Director | 普通株式 | 購入 | 12,077 | $0.00 |
| 2025-05-19 | DIPAOLO, MARK | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2025-05-19 | SCHLESINGER, SARAH J. | Director | 普通株式 | 購入 | 12,077 | $0.00 |
| 2025-05-19 | SCHLESINGER, SARAH J. | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2025-05-19 | HAIMOVITZ, JULES | Director | 普通株式 | 購入 | 12,077 | $0.00 |
| 2025-05-19 | SMALL, DEREK A | Director | 普通株式 | 購入 | 12,077 | $0.00 |
| 2025-05-15 | RAIFELD, PAVEL | 10% Owner | 普通株式 | 購入 | 1,860 | $0.00 |
| 2025-05-15 | BASSO, STEPHEN | Chief Financial Officer | 普通株式 | 購入 | 1,353 | $0.00 |
| 2025-03-14 | RAIFELD, PAVEL | 10% Owner | 普通株式 | 購入 | 37,377 | $17.39 |
| 2025-03-14 | RAIFELD, PAVEL | 10% Owner | ストックオプション | 購入 | 243,750 | $0.00 |
| 2025-03-06 | DENNER, ALEXANDER J | 10% Owner | 普通株式 | 売却 | 1,196,746 | $17.52 |
| 2025-03-05 | DENNER, ALEXANDER J | 10% Owner | 普通株式 | 売却 | 270,374 | $17.63 |
| 2025-03-04 | DENNER, ALEXANDER J | 10% Owner | 普通株式 | 売却 | 151,175 | $17.63 |
| 2025-02-24 | BASSO, STEPHEN | Chief Financial Officer | ストックオプション | 購入 | 100,831 | $0.00 |
| 2025-02-24 | BASSO, STEPHEN | Chief Financial Officer | 普通株式 | 購入 | 10,569 | $18.08 |
| 2025-02-24 | ZHEN, MARIANNE | Chief Accounting Officer | ストックオプション | 購入 | 30,300 | $0.00 |
| 2025-02-24 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 購入 | 8,938 | $18.08 |
| 2025-02-20 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 売却 | 2,565 | $18.07 |
| 2025-02-20 | BASSO, STEPHEN | Chief Financial Officer | 普通株式 | 売却 | 1,106 | $18.07 |
| 2024-11-20 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 売却 | 976 | $19.15 |
| 2024-11-15 | BASSO, STEPHEN | Chief Financial Officer | 普通株式 | 購入 | 843 | $0.00 |
| 2024-11-15 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 購入 | 300 | $0.00 |
| 2024-08-20 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 売却 | 975 | $18.49 |
| 2024-06-17 | SRIVASTAVA, SAPNA | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2024-06-17 | SMALL, DEREK A | Director | 普通株式 | 購入 | 13,923 | $0.00 |
| 2024-06-17 | SMALL, DEREK A | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2024-06-17 | DIPAOLO, MARK | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2024-06-17 | DIPAOLO, MARK | Director | 普通株式 | 購入 | 13,923 | $0.00 |
| 2024-06-17 | HAIMOVITZ, JULES | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2024-06-17 | HAIMOVITZ, JULES | Director | 普通株式 | 購入 | 13,923 | $0.00 |
| 2024-06-17 | ODYSSEAS, KOSTAS D | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2024-06-17 | ODYSSEAS, KOSTAS D | Director | 普通株式 | 購入 | 13,923 | $0.00 |
| 2024-06-17 | SCHLESINGER, SARAH J. | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2024-06-17 | SRIVASTAVA, SAPNA | Director | 普通株式 | 購入 | 13,923 | $0.00 |
| 2024-06-17 | SCHLESINGER, SARAH J. | Director | 普通株式 | 購入 | 13,923 | $0.00 |
| 2024-05-20 | RONSHEIM, MATTHEW | See Remarks | 普通株式 | 売却 | 268 | $16.13 |
| 2024-05-20 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 売却 | 976 | $16.13 |
| 2024-03-05 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 購入 | 10,752 | $14.88 |
| 2024-03-05 | RONSHEIM, MATTHEW | See Remarks | 普通株式 | 購入 | 12,768 | $14.88 |
| 2024-03-05 | ZHEN, MARIANNE | Chief Accounting Officer | ストックオプション | 購入 | 23,022 | $0.00 |
| 2024-03-05 | RAIFELD, PAVEL | Chief Executive Officer | ストックオプション | 購入 | 75,000 | $0.00 |
| 2024-03-05 | RAIFELD, PAVEL | Chief Executive Officer | ストックオプション | 購入 | 100,000 | $0.00 |
| 2024-03-05 | RAIFELD, PAVEL | Chief Executive Officer | ストックオプション | 購入 | 150,000 | $0.00 |
| 2024-03-05 | BASSO, STEPHEN | Chief Financial Officer | ストックオプション | 購入 | 25,899 | $0.00 |
| 2024-03-05 | BASSO, STEPHEN | Chief Financial Officer | 普通株式 | 購入 | 12,096 | $14.88 |
| 2024-03-05 | RONSHEIM, MATTHEW | See Remarks | ストックオプション | 購入 | 27,338 | $0.00 |
| 2024-02-20 | RONSHEIM, MATTHEW | See Remarks | 普通株式 | 売却 | 807 | $15.80 |
| 2024-02-20 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 売却 | 2,862 | $15.80 |
| 2024-01-18 | RONSHEIM, MATTHEW | See Remarks | ストックオプション | 購入 | 60,000 | $0.00 |
| 2024-01-18 | RONSHEIM, MATTHEW | See Remarks | 普通株式 | 売却 | 1,600 | $16.05 |
| 2023-11-20 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 売却 | 784 | $13.62 |
| 2023-11-15 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 購入 | 302 | $0.00 |
| 2023-11-15 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 売却 | 5,405 | $13.97 |
| 2023-11-15 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 売却 | 5,589 | $14.01 |
| 2023-08-31 | BASSO, STEPHEN | Chief Financial Officer | ストックオプション | 購入 | 150,000 | $0.00 |
| 2023-08-18 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 売却 | 785 | $13.64 |
| 2023-07-31 | KOZIEL, MARGARET | Chief Medical Officer | ストックオプション | 購入 | 60,000 | $0.00 |
| 2023-06-15 | DENNER, ALEXANDER J | 10% Owner | 普通株式 | 購入 | 62,000 | $13.13 |
| 2023-06-06 | DENNER, ALEXANDER J | 10% Owner | 普通株式 | 購入 | 8,000 | $13.05 |
| 2023-06-05 | DENNER, ALEXANDER J | 10% Owner | 普通株式 | 購入 | 7,000 | $13.04 |
| 2023-05-30 | DENNER, ALEXANDER J | 10% Owner | 普通株式 | 購入 | 120,000 | $13.01 |
| 2023-05-26 | DENNER, ALEXANDER J | 10% Owner | 普通株式 | 購入 | 30,000 | $13.12 |
| 2023-05-25 | DENNER, ALEXANDER J | 10% Owner | 普通株式 | 購入 | 50,000 | $13.09 |
| 2023-05-22 | DIPAOLO, MARK | Director | 普通株式 | 購入 | 16,495 | $0.00 |
| 2023-05-22 | HAIMOVITZ, JULES | Director | 普通株式 | 購入 | 16,495 | $0.00 |
| 2023-05-22 | SCHLESINGER, SARAH J. | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2023-05-22 | DIPAOLO, MARK | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2023-05-22 | ODYSSEAS, KOSTAS D | Director | 普通株式 | 購入 | 16,495 | $0.00 |
| 2023-05-22 | SCHLESINGER, SARAH J. | Director | 普通株式 | 購入 | 16,495 | $0.00 |
| 2023-05-22 | BIRX, DEBORAH | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2023-05-22 | BIRX, DEBORAH | Director | 普通株式 | 購入 | 16,495 | $0.00 |
| 2023-05-22 | SRIVASTAVA, SAPNA | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2023-05-22 | SRIVASTAVA, SAPNA | Director | 普通株式 | 購入 | 16,495 | $0.00 |
| 2023-05-22 | ODYSSEAS, KOSTAS D | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2023-05-22 | HAIMOVITZ, JULES | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2023-05-19 | DENNER, ALEXANDER J | 10% Owner | 普通株式 | 購入 | 36,000 | $13.48 |
| 2023-05-19 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 売却 | 784 | $13.47 |
| 2023-05-18 | DENNER, ALEXANDER J | 10% Owner | 普通株式 | 購入 | 10,000 | $13.05 |
| 2023-05-17 | DENNER, ALEXANDER J | 10% Owner | 普通株式 | 購入 | 50,000 | $13.07 |
| 2023-05-15 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 購入 | 1,576 | $0.00 |
| 2023-05-11 | DENNER, ALEXANDER J | 10% Owner | 普通株式 | 購入 | 290,000 | $12.34 |
| 2023-04-13 | ZHEN, MARIANNE | Chief Accounting Officer | ストックオプション | 購入 | 20,000 | $0.00 |
| 2023-04-13 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 購入 | 14,344 | $0.00 |
| 2023-03-10 | RAIFELD, PAVEL | Chief Executive Officer | 普通株式 | 購入 | 3,000 | $10.87 |
| 2023-02-17 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 売却 | 1,852 | $12.42 |
| 2023-01-10 | INNOVIVA,, INC. | Director, 10% Owner | 普通株式 | 購入 | $30,000,000.00 | |
| 2022-11-18 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 売却 | 828 | $13.55 |
| 2022-11-15 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 購入 | 433 | $0.00 |
| 2022-08-19 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 売却 | 830 | $14.12 |
| 2022-07-11 | INNOVIVA,, INC. | 10% Owner | 普通株式 | 購入 | 7,598,814 | $2.20 |
| 2022-07-08 | INNOVIVA,, INC. | 10% Owner | 普通株式 | 購入 | 11,671,662 | $2.20 |
| 2022-05-20 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 売却 | 828 | $16.29 |
| 2022-05-13 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 購入 | 1,834 | $0.00 |
| 2022-05-02 | RAIFELD, PAVEL | Chief Executive Officer | ストックオプション | 購入 | 150,000 | $0.00 |
| 2022-04-25 | ODYSSEAS, KOSTAS D | Director | ストックオプション | 購入 | 10,000 | $10,000.00 |
| 2022-04-25 | ODYSSEAS, KOSTAS D | Director | 普通株式 | 購入 | 12,647 | $0.00 |
| 2022-04-25 | SCHLESINGER, SARAH J. | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2022-04-25 | HAIMOVITZ, JULES | Director | 普通株式 | 購入 | 12,647 | $0.00 |
| 2022-04-25 | HAIMOVITZ, JULES | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2022-04-25 | DIPAOLO, MARK | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2022-04-25 | BIRX, DEBORAH | Director | 普通株式 | 購入 | 12,647 | $0.00 |
| 2022-04-25 | BIRX, DEBORAH | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2022-04-25 | BICKERSTAFF, GEORGE | Director | 普通株式 | 購入 | 12,647 | $0.00 |
| 2022-04-25 | BICKERSTAFF, GEORGE | Director | ストックオプション | 購入 | 10,000 | $0.00 |
| 2022-04-25 | DIPAOLO, MARK | Director | 普通株式 | 購入 | 12,647 | $0.00 |
| 2022-04-25 | SCHLESINGER, SARAH J. | Director | 普通株式 | 購入 | 12,647 | $0.00 |
| 2022-03-31 | INNOVIVA,, INC. | Director, 10% Owner | 普通株式 | 購入 | 5,385,208 | $5.00 |
| 2022-03-31 | INNOVIVA,, INC. | Director, 10% Owner | 普通株式 | 購入 | 0 | $5.00 |
| 2022-03-01 | ZHEN, MARIANNE | Chief Accounting Officer | ストックオプション | 購入 | 15,000 | $0.00 |
| 2022-03-01 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 購入 | 6,691 | $0.00 |
| 2022-02-18 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 売却 | 2,277 | $19.99 |
| 2022-02-18 | INNOVIVA,, INC. | 10% Owner | 普通株式 | 購入 | 0 | $ |
| 2022-02-18 | INNOVIVA,, INC. | 10% Owner | 普通株式 | 購入 | 0 | $ |
| 2022-02-09 | INNOVIVA,, INC. | Director, 10% Owner | 普通株式 | 購入 | 1,807,396 | $5.00 |
| 2022-02-09 | INNOVIVA,, INC. | Director, 10% Owner | 普通株式 | 購入 | 3,614,792 | $5.00 |
| 2021-11-19 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 売却 | 758 | $17.05 |
| 2021-10-29 | INNOVIVA,, INC. | Director, 10% Owner | 普通株式 | 購入 | 1,212,122 | $3.30 |
| 2021-08-20 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 売却 | 760 | $15.94 |
| 2021-08-20 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 売却 | 1,129 | $15.89 |
| 2021-08-20 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 購入 | 1,129 | $15.89 |
| 2021-08-19 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 売却 | 2,802 | $16.02 |
| 2021-06-11 | INNOVIVA,, INC. | 10% Owner | 普通株式 | 購入 | 6,268,975 | $2.00 |
| 2021-06-11 | INNOVIVA,, INC. | 10% Owner | 普通株式 | 購入 | 6,268,975 | $2.00 |
| 2021-05-24 | BICKERSTAFF, GEORGE | Director | 普通株式 | 購入 | 10,000 | $13.46 |
| 2021-05-21 | BICKERSTAFF, GEORGE | Director | 普通株式 | 購入 | 10,000 | $12.97 |
| 2021-05-21 | RAIFELD, PAVEL | Chief Executive Officer | ストックオプション | 購入 | 100,000 | $0.00 |
| 2021-05-20 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 売却 | 759 | $13.32 |
| 2021-05-20 | GLAXOSMITHKLINE, PLC | 10% Owner | 普通株式 | 売却 | 32,005,260 | $12.25 |
| 2021-05-14 | HAIMOVITZ, JULES | Director | 普通株式 | 購入 | 17,482 | $0.00 |
| 2021-05-14 | SCHLESINGER, SARAH J. | Director | 普通株式 | 購入 | 17,482 | $0.00 |
| 2021-05-14 | ODYSSEAS, KOSTAS D | Director | 普通株式 | 購入 | 17,482 | $0.00 |
| 2021-05-14 | DIPAOLO, MARK | Director | 普通株式 | 購入 | 17,482 | $0.00 |
| 2021-05-14 | BIRX, DEBORAH | Director | 普通株式 | 購入 | 17,482 | $0.00 |
| 2021-05-14 | BICKERSTAFF, GEORGE | Director | 普通株式 | 購入 | 17,482 | $0.00 |
| 2021-05-03 | INNOVIVA,, INC. | 10% Owner | 普通株式 | 購入 | 3,731,025 | $2.00 |
| 2021-05-03 | INNOVIVA,, INC. | 10% Owner | 普通株式 | 購入 | 3,731,025 | $2.00 |
| 2021-03-29 | ZHEN, MARIANNE | Chief Accounting Officer | ストックオプション | 購入 | 5,000 | $0.00 |
| 2021-03-29 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 購入 | 10,305 | $0.00 |
| 2021-03-29 | BIRX, DEBORAH | Director | 普通株式 | 購入 | 1,612 | $0.00 |
| 2021-03-22 | BIRX, DEBORAH | Director | 譲渡制限付株式ユニット | 購入 | 10,748 | $0.00 |
| 2021-03-17 | INNOVIVA,, INC. | Director, 10% Owner | 普通株式 | 購入 | 4,285,935 | $3.25 |
| 2021-03-17 | INNOVIVA,, INC. | Director, 10% Owner | 普通株式 | 購入 | 4,285,935 | $3.25 |
| 2021-02-19 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 売却 | 2,108 | $11.74 |
| 2021-01-26 | INNOVIVA,, INC. | Director, 10% Owner | 普通株式 | 購入 | 1,867,912 | $3.25 |
| 2021-01-26 | INNOVIVA,, INC. | Director, 10% Owner | 普通株式 | 購入 | 1,867,912 | $3.25 |
| 2020-11-20 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 売却 | 798 | $10.95 |
| 2020-09-01 | INNOVIVA,, INC. | 10% Owner | 普通株式 | 購入 | 4,672,897 | $2.68 |
| 2020-09-01 | INNOVIVA,, INC. | 10% Owner | 普通株式 | 購入 | 4,672,897 | $2.68 |
| 2020-08-20 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 売却 | 797 | $13.19 |
| 2020-06-11 | INNOVIVA,, INC. | 10% Owner | 普通株式 | 購入 | 12,677,490 | $2.50 |
| 2020-06-11 | INNOVIVA,, INC. | 10% Owner | 普通株式 | 購入 | 12,677,490 | $2.50 |
| 2020-05-20 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 売却 | 866 | $14.10 |
| 2020-05-20 | HULME, GEOFFREY | Interim Principal Exec Officer | 普通株式 | 売却 | 339 | $14.10 |
| 2020-04-24 | HAIMOVITZ, JULES | Director | 普通株式 | 購入 | 16,917 | $0.00 |
| 2020-04-24 | ODYSSEAS, KOSTAS D | Director | 普通株式 | 購入 | 16,917 | $0.00 |
| 2020-04-24 | BICKERSTAFF, GEORGE | Director | 普通株式 | 購入 | 16,917 | $0.00 |
| 2020-04-24 | DIPAOLO, MARK | Director | 普通株式 | 購入 | 16,917 | $0.00 |
| 2020-04-24 | SCHLESINGER, SARAH J. | Director | 普通株式 | 購入 | 16,917 | $0.00 |
| 2020-03-27 | INNOVIVA,, INC. | 10% Owner | 普通株式 | 購入 | 7,717,661 | $2.87 |
| 2020-03-27 | INNOVIVA,, INC. | 10% Owner | 普通株式 | 購入 | 7,717,661 | $2.87 |
| 2020-02-24 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 売却 | 2,954 | $14.78 |
| 2020-02-20 | HULME, GEOFFREY | Interim Principal Exec Officer | 普通株式 | 売却 | 1,549 | $15.10 |
| 2020-02-20 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 売却 | 2,073 | $15.10 |
| 2020-02-03 | HULME, GEOFFREY | Interim Principal Exec Officer | 普通株式 | 購入 | 15,734 | $0.00 |
| 2020-02-03 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 購入 | 8,741 | $0.00 |
| 2019-11-20 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 売却 | 602 | $12.59 |
| 2019-09-04 | HULME, GEOFFREY | Interim PEO | 普通株式 | 購入 | 3,000 | $10.89 |
| 2019-08-20 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 売却 | 600 | $11.50 |
| 2019-05-20 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 売却 | 601 | $14.21 |
| 2019-04-24 | HAIMOVITZ, JULES | Director | 普通株式 | 購入 | 16,399 | $0.00 |
| 2019-04-24 | DIPAOLO, MARK | Director | 普通株式 | 購入 | 16,399 | $0.00 |
| 2019-04-24 | ODYSSEAS, KOSTAS D | Director | 普通株式 | 購入 | 16,399 | $0.00 |
| 2019-04-24 | BICKERSTAFF, GEORGE | Director | 普通株式 | 購入 | 16,399 | $0.00 |
| 2019-04-24 | SCHLESINGER, SARAH J. | Director | 普通株式 | 購入 | 16,399 | $0.00 |
| 2019-03-01 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 購入 | 8,154 | $0.00 |
| 2019-03-01 | HULME, GEOFFREY | Interim PEO | 普通株式 | 購入 | 14,677 | $0.00 |
| 2019-02-27 | BICKERSTAFF, GEORGE | Director | 普通株式 | 購入 | 15,000 | $15.90 |
| 2019-02-26 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 売却 | 5,617 | $16.00 |
| 2019-02-21 | BICKERSTAFF, GEORGE | Director | 普通株式 | 購入 | 10,000 | $14.90 |
| 2019-02-20 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 売却 | 1,353 | $14.67 |
| 2019-02-19 | HULME, GEOFFREY | Interim PEO | 普通株式 | 購入 | 9,000 | $0.00 |
| 2019-02-19 | HULME, GEOFFREY | Interim PEO | 普通株式 | 売却 | 3,093 | $14.53 |
| 2019-02-15 | HULME, GEOFFREY | Interim PEO | 普通株式 | 購入 | 7,000 | $14.80 |
| 2018-11-20 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 売却 | 540 | $16.43 |
| 2018-09-07 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 購入 | 1,779 | $0.00 |
| 2018-08-21 | ABERCROMBIE, GEORGE B | Sr. VP & Chief Comm. Officer | 普通株式 | 売却 | 8,000 | $14.11 |
| 2018-08-21 | WITEK, THEODORE J. JR. | Sr. VP & Chief Scientific Off. | 普通株式 | 売却 | 8,504 | $14.12 |
| 2018-08-20 | ABERCROMBIE, GEORGE B | Sr. VP & Chief Comm. Officer | 普通株式 | 売却 | 5,680 | $14.08 |
| 2018-08-20 | ZHEN, MARIANNE | Chief Accounting Officer | 普通株式 | 売却 | 536 | $14.08 |
| 2018-08-20 | WITEK, THEODORE J. JR. | Sr. VP & Chief Scientific Off. | 普通株式 | 売却 | 3,089 | $14.08 |
| 2018-05-21 | DESPARBES, ERIC | SVP and CFO | 普通株式 | 売却 | 5,808 | $14.40 |
| 2018-05-21 | ABERCROMBIE, GEORGE B | Sr. VP & Chief Comm. Officer | 普通株式 | 売却 | 8,000 | $14.40 |
| 2018-05-20 | WITEK, THEODORE J. JR. | Sr. VP & Chief Scientific Off. | 普通株式 | 売却 | 3,089 | $14.59 |
| 2018-05-20 | ABERCROMBIE, GEORGE B | Sr. VP & Chief Comm. Officer | 普通株式 | 売却 | 4,682 | $14.59 |
| 2018-05-20 | DESPARBES, ERIC | SVP and CFO | 普通株式 | 売却 | 7,901 | $14.59 |
| 2018-04-24 | HAIMOVITZ, JULES | Director | 普通株式 | 購入 | 14,249 | $0.00 |
| 2018-04-24 | SCHLESINGER, SARAH J. | Director | 普通株式 | 購入 | 14,249 | $0.00 |
| 2018-04-24 | BICKERSTAFF, GEORGE | Director | 普通株式 | 購入 | 14,249 | $0.00 |
| 2018-04-24 | DIPAOLO, MARK | Director | 普通株式 | 購入 | 14,249 | $0.00 |
| 2018-04-24 | ODYSSEAS, KOSTAS D | Director | 普通株式 | 購入 | 14,249 | $0.00 |
| 2018-03-02 | WITEK, THEODORE J. JR. | Sr. VP & Chief Scientific Off. | 普通株式 | 購入 | 74,444 | $0.00 |
| 2018-03-02 | ABERCROMBIE, GEORGE B | Sr. VP & Chief Comm. Officer | 普通株式 | 購入 | 74,444 | $0.00 |
| 2018-03-02 | DESPARBES, ERIC | Interim PEO, SVP and CFO | 普通株式 | 購入 | 93,056 | $0.00 |
| 2018-02-21 | ABERCROMBIE, GEORGE B | Sr. VP & Chief Comm. Officer | 普通株式 | 売却 | 8,000 | $16.51 |
| 2018-02-21 | DESPARBES, ERIC | Interim PEO, SVP and CFO | 普通株式 | 売却 | 5,378 | $16.52 |
| 2018-02-21 | WITEK, THEODORE J. JR. | Sr. VP & Chief Scientific Off. | 普通株式 | 売却 | 9,890 | $16.60 |
| 2018-02-20 | ABERCROMBIE, GEORGE B | Sr. VP & Chief Comm. Officer | 普通株式 | 売却 | 15,500 | $16.44 |
| 2018-02-20 | WITEK, THEODORE J. JR. | Sr. VP & Chief Scientific Off. | 普通株式 | 売却 | 16,700 | $16.44 |
| 2018-02-20 | DESPARBES, ERIC | Interim PEO, SVP and CFO | 普通株式 | 売却 | 24,876 | $16.44 |
| 2018-02-12 | SCHLESINGER, SARAH J. | Director | 普通株式 | 購入 | 10,517 | $0.00 |
| 2018-02-12 | DIPAOLO, MARK | Director | 普通株式 | 購入 | 10,517 | $0.00 |
| 2018-02-12 | HAIMOVITZ, JULES | Director | 普通株式 | 購入 | 10,517 | $0.00 |
| 2017-12-19 | KOSTAS, ODYSSEAS D | Director | 普通株式 | 購入 | 14,513 | $0.00 |
| 2017-12-19 | BICKERSTAFF, GEORGE | Director | 普通株式 | 購入 | 14,513 | $0.00 |
| 2017-12-04 | AGUIAR, MICHAEL W | Director, President & Chief Exec Officer | 普通株式 | 売却 | 12,022 | $13.13 |
| 2017-11-21 | WITEK, THEODORE J. JR. | Sr. VP & Chief Scientific Off. | 普通株式 | 売却 | 13,000 | $13.29 |
| 2017-11-21 | DESPARBES, ERIC | SVP and CFO | 普通株式 | 売却 | 13,460 | $13.31 |
| 2017-11-21 | ABERCROMBIE, GEORGE B | Sr. VP & Chief Comm. Officer | 普通株式 | 売却 | 5,215 | $13.26 |
| 2017-11-20 | ABERCROMBIE, GEORGE B | Sr. VP & Chief Comm. Officer | 普通株式 | 売却 | 3,358 | $13.17 |
| 2017-11-20 | AGUIAR, MICHAEL W | Director, President & Chief Exec Officer | 普通株式 | 売却 | 43,038 | $13.17 |
| 2017-11-20 | FAERM, MICHAEL E. | Sr VP & Chief Business Officer | 普通株式 | 売却 | 4,470 | $13.17 |
| 2017-11-20 | DESPARBES, ERIC | SVP and CFO | 普通株式 | 売却 | 6,141 | $13.17 |
| 2017-11-20 | WITEK, THEODORE J. JR. | Sr. VP & Chief Scientific Off. | 普通株式 | 売却 | 14,757 | $13.17 |
| 2017-11-20 | DESPARBES, ERIC | SVP and CFO | 普通株式 | 売却 | 1,825 | $13.04 |
| 2017-08-21 | DESPARBES, ERIC | SVP and CFO | 普通株式 | 売却 | 1,825 | $12.20 |
| 2017-08-20 | FAERM, MICHAEL E. | Sr VP & Chief Business Officer | 普通株式 | 売却 | 3,179 | $12.28 |
| 2017-08-20 | WITEK, THEODORE J. JR. | Sr. VP & Chief Scientific Off. | 普通株式 | 売却 | 2,596 | $12.28 |
| 2017-08-20 | DESPARBES, ERIC | SVP and CFO | 普通株式 | 売却 | 5,770 | $12.28 |
| 2017-08-20 | ABERCROMBIE, GEORGE B | Sr. VP & Chief Comm. Officer | 普通株式 | 売却 | 2,886 | $12.28 |
| 2017-08-20 | AGUIAR, MICHAEL W | Director, President & Chief Exec Officer | 普通株式 | 売却 | 12,917 | $12.28 |
| 2017-05-22 | WITEK, THEODORE J. JR. | Sr. VP & Chief Scientific Off. | 普通株式 | 売却 | 7,815 | $12.01 |
| 2017-05-22 | DESPARBES, ERIC | SVP and CFO | 普通株式 | 売却 | 1,825 | $11.85 |
| 2017-05-20 | FAERM, MICHAEL E. | Sr VP & Chief Business Officer | 普通株式 | 売却 | 3,176 | $11.86 |
| 2017-05-20 | WITEK, THEODORE J. JR. | Sr. VP & Chief Scientific Off. | 普通株式 | 売却 | 2,590 | $11.86 |
| 2017-05-20 | ABERCROMBIE, GEORGE B | Sr. VP & Chief Comm. Officer | 普通株式 | 売却 | 2,228 | $11.86 |
| 2017-05-20 | DESPARBES, ERIC | SVP and CFO | 普通株式 | 売却 | 4,208 | $11.86 |
| 2017-05-20 | AGUIAR, MICHAEL W | Director, President & Chief Exec Officer | 普通株式 | 売却 | 12,897 | $11.86 |
| 2017-04-20 | DUNCAN, BARBARA GAYLE | Director | 普通株式 | 購入 | 19,857 | $0.00 |
| 2017-04-20 | TYREE, JAMES L | Director | 普通株式 | 購入 | 19,857 | $0.00 |
| 2017-04-20 | WALTRIP, WILLIAM H | Director | 普通株式 | 購入 | 19,857 | $0.00 |
| 2017-04-20 | PEPE, PAUL | Director | 普通株式 | 購入 | 19,857 | $0.00 |
| 2017-04-20 | FRIEDMAN, CATHY | Director | 普通株式 | 購入 | 19,857 | $0.00 |
| 2017-04-20 | LEPORE, PATRICK G | Director | 普通株式 | 購入 | 19,857 | $0.00 |
| 2017-02-21 | DESPARBES, ERIC | SVP and CFO | 普通株式 | 売却 | 1,825 | $12.07 |
| 2017-02-20 | DESPARBES, ERIC | SVP and CFO | 普通株式 | 売却 | 8,604 | $12.04 |
| 2017-02-20 | AGUIAR, MICHAEL W | Director, President & Chief Exec Officer | 普通株式 | 売却 | 19,429 | $12.04 |
| 2017-02-20 | WITEK, THEODORE J. JR. | Sr. VP & Chief Scientific Off. | 普通株式 | 売却 | 6,367 | $12.04 |
| 2017-02-20 | FAERM, MICHAEL E. | Sr VP & Chief Business Officer | 普通株式 | 売却 | 5,860 | $12.04 |
| 2017-02-20 | ABERCROMBIE, GEORGE B | Sr. VP & Chief Comm. Officer | 普通株式 | 売却 | 5,355 | $12.04 |
| 2017-01-17 | AGUIAR, MICHAEL W | Director, President & Chief Exec Officer | 普通株式 | 購入 | 333,495 | $0.00 |
| 2017-01-17 | WITEK, THEODORE L JR | Sr. VP & Chief Scientific Off. | 普通株式 | 購入 | 106,718 | $0.00 |
| 2017-01-17 | DESPARBES, ERIC | SVP and CFO | 普通株式 | 購入 | 133,398 | $0.00 |
| 2017-01-17 | ABERCROMBIE, GEORGE B | Sr. VP & Chief Comm. Officer | 普通株式 | 購入 | 106,718 | $0.00 |
| 2017-01-17 | FAERM, MICHAEL E. | Sr VP & Chief Business Officer | 普通株式 | 購入 | 133,398 | $0.00 |
| 2016-11-22 | WITEK, THEODORE L JR | Sr. VP & Chief Scientific Off. | 普通株式 | 売却 | 3,700 | $10.84 |
| 2016-11-21 | DESPARBES, ERIC | SVP and CFO | 普通株式 | 売却 | 1,800 | $10.89 |
| 2016-11-20 | DESPARBES, ERIC | SVP and CFO | 普通株式 | 売却 | 3,832 | $10.91 |
| 2016-11-20 | WITEK, THEODORE L JR | Sr. VP & Chief Scientific Off. | 普通株式 | 売却 | 1,487 | $10.91 |
| 2016-11-20 | ABERCROMBIE, GEORGE B | Sr. VP & Chief Comm. Officer | 普通株式 | 売却 | 1,273 | $10.91 |
| 2016-11-20 | FAERM, MICHAEL E. | Sr VP & Chief Business Officer | 普通株式 | 売却 | 2,893 | $10.91 |
| 2016-11-20 | AGUIAR, MICHAEL W | Director, President & Chief Exec Officer | 普通株式 | 売却 | 8,417 | $10.91 |
| 2016-11-18 | DUNCAN, BARBARA GAYLE | Director | 普通株式 | 購入 | 32,461 | $0.00 |
| 2016-11-18 | AGUIAR, MICHAEL W | Director, President & Chief Exec Officer | 普通株式 | 購入 | 63,135 | $0.00 |
| 2016-10-26 | LEPORE, PATRICK G | Director | 普通株式 | 購入 | 38,421 | $0.00 |
| 2016-08-22 | DESPARBES, ERIC | SVP and CFO | 普通株式 | 売却 | 3,700 | $11.77 |
| 2016-08-20 | WITEK, THEODORE L JR | Sr. VP & Chief Scientific Off. | 普通株式 | 売却 | 1,501 | $11.79 |
| 2016-08-20 | ABERCROMBIE, GEORGE B | Sr. VP & Chief Comm. Officer | 普通株式 | 売却 | 1,939 | $11.79 |
| 2016-08-20 | AGUIAR, MICHAEL W | Director, President & Chief Exec Officer | 普通株式 | 売却 | 8,467 | $11.79 |
| 2016-08-20 | DESPARBES, ERIC | SVP and CFO | 普通株式 | 売却 | 2,845 | $11.79 |
| 2016-08-20 | FAERM, MICHAEL E. | Sr VP & Chief Business Officer | 普通株式 | 売却 | 9,544 | $11.79 |
| 2016-05-20 | DESPARBES, ERIC | SVP and CFO | 普通株式 | 売却 | 2,818 | $11.09 |
| 2016-05-20 | AGUIAR, MICHAEL W | Director, President & Chief Exec Officer | 普通株式 | 売却 | 8,428 | $11.09 |
| 2016-05-20 | ABERCROMBIE, GEORGE B | Sr. VP & Chief Comm. Officer | 普通株式 | 売却 | 1,276 | $11.09 |
| 2016-05-20 | WITEK, THEODORE L JR | Sr. VP & Chief Scientific Off. | 普通株式 | 売却 | 1,490 | $11.09 |
| 2016-05-18 | TYREE, JAMES L | Director | 普通株式 | 売却 | 813 | $10.47 |
| 2016-04-26 | FRIEDMAN, CATHY | Director | 普通株式 | 購入 | 18,328 | $0.00 |
| 2016-04-26 | WALTRIP, WILLIAM H | Director | 普通株式 | 購入 | 18,328 | $0.00 |
| 2016-04-26 | TYREE, JAMES L | Director | 普通株式 | 購入 | 18,328 | $0.00 |
| 2016-04-26 | PEPE, PAUL | Director | 普通株式 | 購入 | 18,328 | $0.00 |
| 2016-02-19 | ABERCROMBIE, GEORGE B | Sr. VP & Chief Comm. Officer | 普通株式 | 売却 | 5,376 | $12.28 |
| 2016-02-19 | WITEK, THEODORE L JR | Sr. VP & Chief Scientific Off. | 普通株式 | 売却 | 6,486 | $12.28 |
| 2016-02-19 | AGUIAR, MICHAEL W | Director, President & Chief Exec Officer | 普通株式 | 売却 | 18,659 | $12.28 |
| 2016-02-19 | DESPARBES, ERIC | SVP and CFO | 普通株式 | 売却 | 5,457 | $12.28 |
| 2016-01-14 | FAERM, MICHAEL E. | Sr VP & Chief Business Officer | 普通株式 | 購入 | 67,126 | $0.00 |
| 2016-01-14 | AGUIAR, MICHAEL W | Director, President & Chief Exec Officer | 普通株式 | 購入 | 289,334 | $0.00 |
| 2016-01-14 | ABERCROMBIE, GEORGE B | Sr. VP & Chief Comm. Officer | 普通株式 | 購入 | 92,587 | $0.00 |
| 2016-01-14 | DESPARBES, ERIC | SVP and CFO | 普通株式 | 購入 | 115,734 | $0.00 |
| 2016-01-14 | WITEK, THEODORE L JR | Sr. VP & Chief Scientific Off. | 普通株式 | 購入 | 92,587 | $0.00 |
| 2015-11-20 | DESPARBES, ERIC | SVP and CFO | 普通株式 | 売却 | 7,940 | $8.92 |
| 2015-08-07 | GLAXOSMITHKLINE, PLC | 10% Owner | 普通株式 | 購入 | 245,828 | $3,485,841.04 |
| 2015-07-23 | FAERM, MICHAEL E. | Sr VP & Chief Business Officer | 普通株式 | 購入 | 105,288 | $0.00 |
| 2015-06-02 | AGUIAR, MICHAEL W | Director, President & CEO | 普通株式 | 売却 | 24,698 | $16.68 |
| 2015-06-02 | TYREE, JAMES L | Director | 普通株式 | 売却 | 2,438 | $16.85 |
| 2015-05-27 | WALTRIP, WILLIAM H | Director | 普通株式 | 売却 | 16,313 | $16.32 |
| 2015-05-27 | WALTRIP, WILLIAM H | Director | ストックオプション | 売却 | 16,313 | $0.00 |
| 2015-05-27 | WALTRIP, WILLIAM H | Director | 普通株式 | 購入 | 16,313 | $13.45 |
| 2015-05-20 | AGUIAR, MICHAEL W | Director, President & CEO | 普通株式 | 売却 | 3,256 | $16.24 |
| 2015-05-11 | GLAXOSMITHKLINE, PLC | 10% Owner | 普通株式 | 購入 | 85,579 | $1,369,264.00 |
| 2015-04-24 | KEARNEY, TERRENCE C | Director | 普通株式 | 購入 | 13,950 | $0.00 |
| 2015-04-24 | PEPE, PAUL | Director | 普通株式 | 購入 | 13,950 | $0.00 |
| 2015-04-24 | WALTRIP, WILLIAM H | Director | 普通株式 | 購入 | 13,950 | $0.00 |
| 2015-04-24 | TYREE, JAMES L | Director | 普通株式 | 購入 | 13,950 | $0.00 |
| 2015-04-24 | FRIEDMAN, CATHY | Director | 普通株式 | 購入 | 13,950 | $0.00 |
| 2015-03-02 | GLAXOSMITHKLINE, PLC | 10% Owner | 普通株式 | 購入 | 92,674 | $1,673,692.44 |
| 2015-02-20 | AGUIAR, MICHAEL W | Director, President & CEO | 普通株式 | 売却 | 6,789 | $18.22 |
| 2015-01-07 | DESPARBES, ERIC | SVP and CFO | 普通株式 | 購入 | 36,972 | $0.00 |
| 2015-01-07 | WITEK, THEODORE L JR | Sr. VP, Corp Partnerships | 普通株式 | 購入 | 71,429 | $0.00 |
| 2015-01-07 | ABERCROMBIE, GEORGE B | Sr. VP, Corp. Partnerships | 普通株式 | 購入 | 71,429 | $0.00 |
| 2015-01-07 | AGUIAR, MICHAEL W | Director, President & CEO | 普通株式 | 購入 | 176,056 | $0.00 |
| 2014-12-22 | TYREE, JAMES L | Director | 普通株式 | 購入 | 6,500 | $0.00 |
| 2014-12-22 | PEPE, PAUL | Director | 普通株式 | 購入 | 6,500 | $0.00 |
| 2014-12-22 | WALTRIP, WILLIAM H | Director | 普通株式 | 購入 | 3,250 | $0.00 |
| 2014-12-22 | FRIEDMAN, CATHY | Director | 普通株式 | 購入 | 6,500 | $0.00 |
| 2014-11-04 | GLAXOSMITHKLINE, PLC | 10% Owner | 普通株式 | 購入 | 832,456 | $12,786,524.16 |
| 2014-10-30 | KEARNEY, TERRENCE C | Director | 普通株式 | 購入 | 23,133 | $0.00 |
| 2014-10-16 | DESPARBES, ERIC | SVP and CFO | 普通株式 | 購入 | 102,471 | $0.00 |
| 2014-08-20 | BLUM, LEONARD M | Sr VP, Chief Comm. Officer | 普通株式 | 売却 | 3,261 | $22.76 |
| 2014-08-20 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 3,261 | $22.76 |
| 2014-08-20 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 売却 | 3,261 | $22.76 |
| 2014-08-20 | LEE, JUNNING | Sr. VP, Technical Operations | 普通株式 | 売却 | 3,261 | $22.76 |
| 2014-08-15 | AGUIAR, MICHAEL W | Director, President & CEO | 普通株式 | 購入 | 43,905 | $0.00 |
| 2014-08-15 | WINNINGHAM, RICK E | Director | 普通株式 | 売却 | 96,250 | $0.00 |
| 2014-08-13 | LEE, JUNNING | Sr. VP, Technical Operations | 普通株式 | 購入 | 12,516 | $14.53 |
| 2014-08-13 | LEE, JUNNING | Sr. VP, Technical Operations | 普通株式 | 購入 | 13,882 | $9.81 |
| 2014-08-13 | LEE, JUNNING | Sr. VP, Technical Operations | ストックオプション | 売却 | 24,338 | $0.00 |
| 2014-08-13 | LEE, JUNNING | Sr. VP, Technical Operations | ストックオプション | 売却 | 23,705 | $0.00 |
| 2014-08-13 | LEE, JUNNING | Sr. VP, Technical Operations | ストックオプション | 売却 | 12,516 | $0.00 |
| 2014-08-13 | LEE, JUNNING | Sr. VP, Technical Operations | ストックオプション | 売却 | 13,882 | $0.00 |
| 2014-08-13 | LEE, JUNNING | Sr. VP, Technical Operations | 普通株式 | 売却 | 53,424 | $22.50 |
| 2014-08-13 | LEE, JUNNING | Sr. VP, Technical Operations | 普通株式 | 購入 | 23,705 | $12.66 |
| 2014-08-13 | LEE, JUNNING | Sr. VP, Technical Operations | 普通株式 | 購入 | 24,338 | $12.66 |
| 2014-08-12 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 1,048 | $22.30 |
| 2014-08-11 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 27,108 | $22.12 |
| 2014-08-11 | GLAXOSMITHKLINE, PLC | 10% Owner | 普通株式 | 購入 | 172,651 | $3,912,271.66 |
| 2014-08-11 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | ストックオプション | 購入 | 33,667 | $14.53 |
| 2014-08-11 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 購入 | 33,667 | $14.53 |
| 2014-07-24 | WITEK, THEODORE L JR | Sr. VP, Corp Partnerships | ストックオプション | 購入 | 125,000 | $0.00 |
| 2014-06-19 | ABERCROMBIE, GEORGE B | Sr. VP, Corp. Partnerships | ストックオプション | 購入 | 100,000 | $0.00 |
| 2014-06-19 | ABERCROMBIE, GEORGE B | Sr. VP, Corp. Partnerships | 普通株式 | 購入 | 10,000 | $0.00 |
| 2014-06-16 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | 普通株式 | 購入 | 28,365 | $0.00 |
| 2014-06-16 | BLUM, LEONARD M | Sr VP, Chief Comm. Officer | 普通株式 | 購入 | 28,365 | $0.00 |
| 2014-06-16 | LEE, JUNNING | Sr. VP, Technical Operations | 普通株式 | 購入 | 19,855 | $0.00 |
| 2014-06-16 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 購入 | 28,365 | $0.00 |
| 2014-06-16 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 購入 | 28,365 | $0.00 |
| 2014-06-16 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 購入 | 62,403 | $0.00 |
| 2014-06-02 | FRIEDMAN, CATHY | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2014-06-02 | FRIEDMAN, CATHY | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2014-06-02 | PEPE, PAUL | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2014-06-02 | TYREE, JAMES L | Director | ストックオプション | 購入 | 7,585 | $0.00 |
| 2014-06-02 | TYREE, JAMES L | Director | 普通株式 | 購入 | 7,585 | $0.00 |
| 2014-06-02 | BLUM, LEONARD M | Sr VP, Chief Comm. Officer | 普通株式 | 購入 | 21,000 | $0.00 |
| 2014-06-02 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | 普通株式 | 購入 | 21,000 | $0.00 |
| 2014-06-02 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 購入 | 21,000 | $0.00 |
| 2014-06-02 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 購入 | 50,000 | $0.00 |
| 2014-06-02 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 購入 | 21,000 | $0.00 |
| 2014-06-02 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 購入 | 50,000 | $0.00 |
| 2014-06-02 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 購入 | 46,200 | $0.00 |
| 2014-06-02 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 購入 | 110,000 | $0.00 |
| 2014-06-02 | PEPE, PAUL | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2014-06-02 | PEPE, PAUL | Director | 普通株式 | 購入 | 7,585 | $0.00 |
| 2014-06-02 | PEPE, PAUL | Director | ストックオプション | 購入 | 7,585 | $0.00 |
| 2014-06-02 | FRIEDMAN, CATHY | Director | 普通株式 | 購入 | 7,585 | $0.00 |
| 2014-06-02 | FRIEDMAN, CATHY | Director | ストックオプション | 購入 | 7,585 | $0.00 |
| 2014-06-02 | TYREE, JAMES L | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2014-06-02 | TYREE, JAMES L | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2014-06-02 | LEE, JUNNING | Sr. VP, Technical Operations | 普通株式 | 購入 | 50,000 | $0.00 |
| 2014-06-02 | LEE, JUNNING | Sr. VP, Technical Operations | 普通株式 | 購入 | 14,700 | $0.00 |
| 2014-06-02 | BLUM, LEONARD M | Sr VP, Chief Comm. Officer | 普通株式 | 購入 | 50,000 | $0.00 |
| 2014-06-02 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | 普通株式 | 購入 | 50,000 | $0.00 |
| 2014-05-22 | WALTRIP, WILLIAM H | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2014-05-22 | GUNDERSON, ROBERT V JR | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2014-05-22 | MALKIEL, BURTON G | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2014-05-22 | RINGROSE, PETER S | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2014-05-22 | RINGROSE, PETER S | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2014-05-22 | MALKIEL, BURTON G | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2014-05-22 | FORE, HENRIETTA | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2014-05-22 | FORE, HENRIETTA | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2014-05-22 | GUNDERSON, ROBERT V JR | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2014-05-22 | WHITESIDES, GEORGE M | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2014-05-22 | WHITESIDES, GEORGE M | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2014-05-22 | YOUNG, WILLIAM D | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2014-05-22 | YOUNG, WILLIAM D | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2014-05-22 | WALTRIP, WILLIAM H | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2014-05-15 | THERAVANCE, INC | 10% Owner | 普通株式 | 売却 | 33,100,000 | $0.00 |
| 2014-05-09 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 売却 | 22,833 | $26.86 |
| 2014-05-09 | GLAXOSMITHKLINE, PLC | 10% Owner | 普通株式 | 購入 | 317,770 | $8,544,835.30 |
| 2014-05-09 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 売却 | 50,225 | $26.86 |
| 2014-05-09 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 22,833 | $26.86 |
| 2014-05-09 | LEE, JUNNING | Sr. VP, Technical Operations | 普通株式 | 売却 | 14,650 | $26.86 |
| 2014-05-09 | BLUM, LEONARD M | Sr VP, Chief Comm. Officer | 普通株式 | 売却 | 18,849 | $26.86 |
| 2014-05-09 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | 普通株式 | 売却 | 21,405 | $26.86 |
| 2014-04-27 | BLUM, LEONARD M | Sr VP, Chief Comm. Officer | 普通株式 | 購入 | 37,500 | $0.00 |
| 2014-04-27 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 購入 | 37,500 | $0.00 |
| 2014-04-27 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 購入 | 82,500 | $0.00 |
| 2014-04-27 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | 普通株式 | 購入 | 37,500 | $0.00 |
| 2014-04-27 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 購入 | 37,500 | $0.00 |
| 2014-04-27 | LEE, JUNNING | Sr. VP, Technical Operations | 普通株式 | 購入 | 26,250 | $0.00 |
| 2014-04-17 | GUNDERSON, ROBERT V JR | Director | 普通株式 | 購入 | 25,806 | $9.69 |
| 2014-04-17 | GUNDERSON, ROBERT V JR | Director | ストックオプション | 売却 | 25,806 | $0.00 |
| 2014-04-07 | YOUNG, WILLIAM D | Director | ストックオプション | 売却 | 25,806 | $0.00 |
| 2014-04-07 | YOUNG, WILLIAM D | Director | 普通株式 | 購入 | 25,806 | $9.69 |
| 2014-03-31 | WALTRIP, WILLIAM H | Director | ストックオプション | 購入 | 25,806 | $0.00 |
| 2014-03-31 | WALTRIP, WILLIAM H | Director | 普通株式 | 購入 | 25,806 | $9.69 |
| 2014-03-21 | LEVINE, ARNOLD J | Director | ストックオプション | 売却 | 25,806 | $0.00 |
| 2014-03-21 | LEVINE, ARNOLD J | Director | 普通株式 | 購入 | 25,806 | $9.69 |
| 2014-03-13 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 売却 | 1,200 | $0.00 |
| 2014-03-06 | WHITESIDES, GEORGE M | Director | ストックオプション | 売却 | 25,806 | $0.00 |
| 2014-03-06 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 購入 | 12,903 | $12.40 |
| 2014-03-06 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 購入 | 29,250 | $16.00 |
| 2014-03-06 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | ストックオプション | 売却 | 12,903 | $0.00 |
| 2014-03-06 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | ストックオプション | 売却 | 29,250 | $0.00 |
| 2014-03-06 | WHITESIDES, GEORGE M | Director | 普通株式 | 購入 | 25,806 | $9.69 |
| 2014-03-03 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 購入 | 30,967 | $9.69 |
| 2014-03-03 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | ストックオプション | 売却 | 65,806 | $0.00 |
| 2014-03-03 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | ストックオプション | 売却 | 30,967 | $0.00 |
| 2014-03-03 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 1,800 | $37.23 |
| 2014-03-03 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 64,006 | $36.72 |
| 2014-03-03 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 購入 | 65,806 | $9.69 |
| 2014-02-27 | MALKIEL, BURTON G | Director | 普通株式 | 売却 | 1,000 | $0.00 |
| 2014-02-20 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 売却 | 9,297 | $39.98 |
| 2014-02-20 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 4,310 | $39.98 |
| 2014-02-20 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | 普通株式 | 売却 | 4,302 | $39.98 |
| 2014-02-20 | BLUM, LEONARD M | Sr VP, Chief Comm. Officer | 普通株式 | 売却 | 4,311 | $39.98 |
| 2014-02-20 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 売却 | 4,307 | $39.98 |
| 2014-02-20 | LEE, JUNNING | Sr. VP, Technical Operations | 普通株式 | 売却 | 3,854 | $39.98 |
| 2014-02-14 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 売却 | 4,600 | $40.04 |
| 2014-02-14 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 売却 | 30,400 | $39.26 |
| 2014-02-11 | GLAXOSMITHKLINE, PLC | 10% Owner | 普通株式 | 購入 | 342,229 | $12,850,698.95 |
| 2014-01-23 | LEE, JUNNING | Sr. VP, Technical Operations | 普通株式 | 購入 | 11,000 | $0.00 |
| 2014-01-23 | PASQUALONE, FRANK | Sr. Vice President, Operations | 普通株式 | 購入 | 20,000 | $0.00 |
| 2014-01-23 | PASQUALONE, FRANK | Sr. Vice President, Operations | ストックオプション | 購入 | 150,000 | $0.00 |
| 2013-11-20 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 4,569 | $36.40 |
| 2013-11-20 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 売却 | 10,046 | $36.40 |
| 2013-11-20 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 売却 | 4,569 | $36.40 |
| 2013-11-20 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | 普通株式 | 売却 | 4,569 | $36.40 |
| 2013-10-29 | GLAXOSMITHKLINE, PLC | 10% Owner | 普通株式 | 購入 | 130,473 | $4,913,613.18 |
| 2013-10-22 | JONKER, JEFFREY DAVID | Senior VP, Corp. & Bus. Dev. | 普通株式 | 購入 | 15,000 | $0.00 |
| 2013-10-22 | JONKER, JEFFREY DAVID | Senior VP, Corp. & Bus. Dev. | ストックオプション | 購入 | 150,000 | $0.00 |
| 2013-09-12 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 売却 | 22,353 | $40.03 |
| 2013-08-21 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | ストックオプション | 売却 | 18,750 | $0.00 |
| 2013-08-21 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 購入 | 18,750 | $16.00 |
| 2013-08-20 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 3,773 | $35.89 |
| 2013-08-20 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | 普通株式 | 売却 | 4,570 | $35.89 |
| 2013-08-20 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 売却 | 10,046 | $35.89 |
| 2013-08-20 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 売却 | 3,813 | $35.89 |
| 2013-07-30 | GLAXOSMITHKLINE, PLC | 10% Owner | 普通株式 | 購入 | 3,064,407 | $111,850,855.50 |
| 2013-07-30 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 売却 | 7,000 | $36.51 |
| 2013-07-24 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 購入 | 11,000 | $0.00 |
| 2013-07-24 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | 普通株式 | 購入 | 5,000 | $0.00 |
| 2013-07-24 | BLUM, LEONARD M | Sr VP, Chief Comm. Officer | 普通株式 | 購入 | 5,000 | $0.00 |
| 2013-07-24 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 購入 | 5,000 | $0.00 |
| 2013-07-24 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 購入 | 5,000 | $0.00 |
| 2013-06-07 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 31,038 | $35.04 |
| 2013-05-29 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 購入 | 6,451 | $12.40 |
| 2013-05-29 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | ストックオプション | 売却 | 4,570 | $0.00 |
| 2013-05-29 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | ストックオプション | 売却 | 6,451 | $0.00 |
| 2013-05-29 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 売却 | 3,808 | $35.01 |
| 2013-05-29 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 購入 | 4,570 | $3.10 |
| 2013-05-20 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 売却 | 2,443 | $37.01 |
| 2013-05-20 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 3,292 | $37.01 |
| 2013-05-20 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 売却 | 10,046 | $37.01 |
| 2013-05-20 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | 普通株式 | 売却 | 4,570 | $37.01 |
| 2013-05-20 | BLUM, LEONARD M | Sr VP, Chief Comm. Officer | 普通株式 | 売却 | 3,292 | $37.01 |
| 2013-05-20 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 売却 | 3,292 | $37.01 |
| 2013-05-13 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 売却 | 16,129 | $40.33 |
| 2013-05-13 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 購入 | 16,129 | $34.00 |
| 2013-05-13 | BRINKLEY, DAVID L | Head of Business Dev. | ストックオプション | 売却 | 16,129 | $0.00 |
| 2013-05-03 | BRINKLEY, DAVID L | Head of Business Dev. | ストックオプション | 売却 | 16,129 | $0.00 |
| 2013-05-03 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 購入 | 16,129 | $29.65 |
| 2013-05-03 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 売却 | 16,129 | $34.77 |
| 2013-04-30 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 売却 | 253,955 | $33.64 |
| 2013-04-30 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 売却 | 6,800 | $33.72 |
| 2013-04-30 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 売却 | 200 | $34.34 |
| 2013-04-30 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 購入 | 8,333 | $6.15 |
| 2013-04-30 | BRINKLEY, DAVID L | Head of Business Dev. | ストックオプション | 売却 | 8,333 | $0.00 |
| 2013-04-30 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | 普通株式 | 購入 | 170,879 | $17.91 |
| 2013-04-30 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | 普通株式 | 売却 | 160,779 | $33.77 |
| 2013-04-30 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | 普通株式 | 売却 | 10,100 | $34.34 |
| 2013-04-30 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | ストックオプション | 売却 | 170,879 | $0.00 |
| 2013-04-30 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 売却 | 17,004 | $33.76 |
| 2013-04-30 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 売却 | 100 | $34.35 |
| 2013-04-30 | GLAXOSMITHKLINE, PLC | 10% Owner | 普通株式 | 購入 | 193,563 | $6,699,215.43 |
| 2013-04-30 | WINNINGHAM, RICK E | Director, Chief Executive Officer | ストックオプション | 売却 | 385,161 | $0.00 |
| 2013-04-30 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 売却 | 1,577 | $34.32 |
| 2013-04-30 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 購入 | 385,161 | $9.69 |
| 2013-04-24 | FORE, HENRIETTA | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2013-04-24 | GUNDERSON, ROBERT V JR | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2013-04-24 | LEVINE, ARNOLD J | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2013-04-24 | WHITESIDES, GEORGE M | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2013-04-24 | YOUNG, WILLIAM D | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2013-04-24 | YOUNG, WILLIAM D | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2013-04-24 | MALKIEL, BURTON G | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2013-04-24 | FORE, HENRIETTA | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2013-04-24 | GUNDERSON, ROBERT V JR | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2013-04-24 | LEVINE, ARNOLD J | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2013-04-24 | MALKIEL, BURTON G | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2013-04-24 | RINGROSE, PETER S | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2013-04-24 | RINGROSE, PETER S | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2013-04-24 | WALTRIP, WILLIAM H | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2013-04-24 | WALTRIP, WILLIAM H | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2013-04-24 | WHITESIDES, GEORGE M | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2013-02-20 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 売却 | 3,416 | $22.10 |
| 2013-02-20 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 売却 | 7,000 | $22.14 |
| 2013-02-20 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 売却 | 5,002 | $22.10 |
| 2013-02-20 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 5,004 | $22.10 |
| 2013-02-20 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 売却 | 10,655 | $22.10 |
| 2013-02-15 | GLAXOSMITHKLINE, PLC | 10% Owner | 普通株式 | 購入 | 116,527 | $2,567,089.81 |
| 2013-02-07 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 購入 | 5,000 | $0.00 |
| 2013-02-07 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 購入 | 11,000 | $0.00 |
| 2013-02-07 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 購入 | 5,000 | $0.00 |
| 2013-02-07 | BLUM, LEONARD M | Sr VP, Chief Comm. Officer | 普通株式 | 購入 | 5,000 | $0.00 |
| 2013-02-07 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 購入 | 5,000 | $0.00 |
| 2013-02-07 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | 普通株式 | 購入 | 5,000 | $0.00 |
| 2013-01-11 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | ストックオプション | 売却 | 11,855 | $0.00 |
| 2013-01-11 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 購入 | 2,655 | $3.10 |
| 2013-01-11 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 購入 | 11,855 | $3.10 |
| 2013-01-11 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | ストックオプション | 売却 | 2,655 | $0.00 |
| 2012-12-31 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 売却 | 460 | $0.00 |
| 2012-12-04 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | $166,025.00 | |
| 2012-11-20 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 売却 | 4,874 | $21.08 |
| 2012-11-20 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 売却 | 3,054 | $21.08 |
| 2012-11-20 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 4,874 | $21.08 |
| 2012-11-14 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 購入 | 5,161 | $3.10 |
| 2012-11-14 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | ストックオプション | 売却 | 5,161 | $0.00 |
| 2011-12-09 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | 普通株式 | 売却 | 10,000 | $21.86 |
| 2011-11-28 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | ストックオプション | 売却 | 14,076 | $0.00 |
| 2011-11-28 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 購入 | 14,076 | $8.53 |
| 2011-11-28 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 購入 | 16,129 | $8.53 |
| 2011-11-28 | DRAZAN, JEFFREY M | Director | 普通株式 | 売却 | 4,293 | $21.00 |
| 2011-11-28 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 20,000 | $21.00 |
| 2011-11-28 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | ストックオプション | 売却 | 16,129 | $0.00 |
| 2011-11-20 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 2,121 | $22.34 |
| 2011-11-20 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | 普通株式 | 売却 | 2,532 | $22.34 |
| 2011-11-20 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 売却 | 6,218 | $22.34 |
| 2011-11-20 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 売却 | 1,887 | $22.34 |
| 2011-11-20 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 売却 | 2,250 | $22.34 |
| 2011-11-01 | GLAXOSMITHKLINE, PLC | 10% Owner | 普通株式 | 購入 | 58,411 | $22.23 |
| 2011-09-01 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 購入 | 3,225 | $8.53 |
| 2011-09-01 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | ストックオプション | 売却 | 3,225 | $0.00 |
| 2011-08-20 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | 普通株式 | 売却 | 2,532 | $17.50 |
| 2011-08-20 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 売却 | 1,889 | $17.50 |
| 2011-08-20 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 売却 | 2,248 | $17.50 |
| 2011-08-20 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 2,120 | $17.50 |
| 2011-08-02 | GLAXOSMITHKLINE, PLC | 10% Owner | 普通株式 | 購入 | 102,466 | $19.71 |
| 2011-07-21 | GLAXOSMITHKLINE, PLC | 10% Owner | 普通株式 | 売却 | 9,401,499 | $0.00 |
| 2011-07-21 | GLAXOSMITHKLINE, PLC | 10% Owner | 普通株式 | 購入 | 9,401,499 | $0.00 |
| 2011-06-17 | LEVINE, ARNOLD J | Director | 普通株式 | 購入 | 20,028 | $0.00 |
| 2011-06-14 | DRAZAN, JEFFREY M | Director | 普通株式 | 売却 | $341,588.00 | |
| 2011-06-14 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | 普通株式 | 売却 | 14,225 | $22.94 |
| 2011-06-07 | DRAZAN, JEFFREY M | Director | 普通株式 | 売却 | 31,907 | $23.29 |
| 2011-06-06 | DRAZAN, JEFFREY M | Director | 普通株式 | 売却 | 37,344 | $23.08 |
| 2011-05-31 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 売却 | 51,500 | $25.65 |
| 2011-05-31 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 購入 | 44,402 | $9.69 |
| 2011-05-31 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 購入 | 1,039 | $18.37 |
| 2011-05-31 | BRINKLEY, DAVID L | Head of Business Dev. | ストックオプション | 売却 | 1,039 | $0.00 |
| 2011-05-31 | BRINKLEY, DAVID L | Head of Business Dev. | ストックオプション | 売却 | 44,402 | $0.00 |
| 2011-05-27 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 購入 | 2,789 | $3.10 |
| 2011-05-27 | BRINKLEY, DAVID L | Head of Business Dev. | ストックオプション | 売却 | 52,371 | $0.00 |
| 2011-05-27 | BRINKLEY, DAVID L | Head of Business Dev. | ストックオプション | 売却 | 2,789 | $0.00 |
| 2011-05-27 | BRINKLEY, DAVID L | Head of Business Dev. | ストックオプション | 売却 | 2,652 | $0.00 |
| 2011-05-27 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 売却 | 57,812 | $25.31 |
| 2011-05-27 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 購入 | 52,371 | $9.69 |
| 2011-05-27 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 購入 | 2,652 | $3.10 |
| 2011-05-20 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 売却 | 1,883 | $25.48 |
| 2011-05-20 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 売却 | 2,245 | $25.48 |
| 2011-05-20 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | 普通株式 | 売却 | 2,527 | $25.48 |
| 2011-05-20 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 2,116 | $25.48 |
| 2011-05-11 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 売却 | 73,100 | $26.28 |
| 2011-05-10 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 売却 | 54,646 | $26.41 |
| 2011-05-03 | GLAXOSMITHKLINE, PLC | 10% Owner | 普通株式 | 購入 | 261,299 | $25.60 |
| 2011-04-27 | FORE, HENRIETTA | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2011-04-27 | GUNDERSON, ROBERT V JR | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2011-04-27 | YOUNG, WILLIAM D | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2011-04-27 | YOUNG, WILLIAM D | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2011-04-27 | WHITESIDES, GEORGE M | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2011-04-27 | WHITESIDES, GEORGE M | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2011-04-27 | WALTRIP, WILLIAM H | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2011-04-27 | WALTRIP, WILLIAM H | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2011-04-27 | RINGROSE, PETER S | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2011-04-27 | GUNDERSON, ROBERT V JR | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2011-04-27 | MALKIEL, BURTON G | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2011-04-27 | RINGROSE, PETER S | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2011-04-27 | MALKIEL, BURTON G | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2011-04-27 | DRAZAN, JEFFREY M | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2011-04-27 | DRAZAN, JEFFREY M | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2011-04-27 | FORE, HENRIETTA | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2011-04-27 | LEVINE, ARNOLD J | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2011-04-27 | LEVINE, ARNOLD J | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2011-03-16 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 売却 | 2,100 | $22.02 |
| 2011-03-16 | BRINKLEY, DAVID L | Head of Business Dev. | ストックオプション | 売却 | 2,100 | $0.00 |
| 2011-03-16 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 購入 | 2,100 | $3.10 |
| 2011-03-15 | BRINKLEY, DAVID L | Head of Business Dev. | ストックオプション | 売却 | 3,931 | $0.00 |
| 2011-03-15 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 購入 | 3,290 | $3.10 |
| 2011-03-15 | BRINKLEY, DAVID L | Head of Business Dev. | ストックオプション | 売却 | 38,271 | $0.00 |
| 2011-03-15 | BRINKLEY, DAVID L | Head of Business Dev. | ストックオプション | 売却 | 3,290 | $0.00 |
| 2011-03-15 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 購入 | 3,931 | $3.10 |
| 2011-03-15 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 購入 | 38,271 | $8.53 |
| 2011-03-15 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 売却 | 45,492 | $22.08 |
| 2011-03-11 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 6,451 | $22.75 |
| 2011-03-11 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 20,238 | $22.76 |
| 2011-03-07 | YOUNG, WILLIAM D | Director | 普通株式 | 売却 | 5,376 | $22.31 |
| 2011-03-07 | YOUNG, WILLIAM D | Director | ストックオプション | 売却 | 10,752 | $0.00 |
| 2011-03-07 | YOUNG, WILLIAM D | Director | 普通株式 | 購入 | 10,752 | $8.53 |
| 2011-03-03 | DRAZAN, JEFFREY M | Director | 普通株式 | 売却 | $1,762,933.00 | |
| 2011-03-02 | DRAZAN, JEFFREY M | Director | 普通株式 | 売却 | $1,743,273.00 | |
| 2011-03-01 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 売却 | 63,873 | $22.53 |
| 2011-02-28 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 売却 | 29,800 | $22.49 |
| 2011-02-28 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 売却 | 37,200 | $23.49 |
| 2011-02-28 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 購入 | 101,752 | $8.53 |
| 2011-02-28 | WINNINGHAM, RICK E | Director, Chief Executive Officer | ストックオプション | 売却 | 101,752 | $0.00 |
| 2011-02-25 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 売却 | 42,000 | $22.74 |
| 2011-02-25 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 購入 | 135,850 | $8.53 |
| 2011-02-25 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 売却 | 50,200 | $22.22 |
| 2011-02-25 | WINNINGHAM, RICK E | Director, Chief Executive Officer | ストックオプション | 売却 | 135,850 | $0.00 |
| 2011-02-24 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 購入 | 135,950 | $8.53 |
| 2011-02-24 | WINNINGHAM, RICK E | Director, Chief Executive Officer | ストックオプション | 売却 | 135,950 | $0.00 |
| 2011-02-24 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 売却 | 93,100 | $21.45 |
| 2011-02-23 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 購入 | 142,500 | $8.53 |
| 2011-02-23 | WINNINGHAM, RICK E | Director, Chief Executive Officer | ストックオプション | 売却 | 142,500 | $0.00 |
| 2011-02-23 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 売却 | 97,600 | $21.14 |
| 2011-02-22 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 売却 | 158,500 | $21.43 |
| 2011-02-22 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 購入 | 246,411 | $8.53 |
| 2011-02-22 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 購入 | 11,729 | $8.53 |
| 2011-02-22 | WINNINGHAM, RICK E | Director, Chief Executive Officer | ストックオプション | 売却 | 246,411 | $0.00 |
| 2011-02-22 | WINNINGHAM, RICK E | Director, Chief Executive Officer | ストックオプション | 売却 | 11,729 | $0.00 |
| 2011-02-22 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 売却 | 10,300 | $22.15 |
| 2011-02-20 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 売却 | 3,240 | $22.50 |
| 2011-02-20 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | 普通株式 | 売却 | 3,511 | $22.50 |
| 2011-02-20 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 売却 | 6,790 | $22.50 |
| 2011-02-20 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 売却 | 2,480 | $22.50 |
| 2011-02-20 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 3,111 | $22.50 |
| 2011-02-18 | YOUNG, WILLIAM D | Director | ストックオプション | 売却 | 10,752 | $0.00 |
| 2011-02-18 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 売却 | 3,701 | $23.12 |
| 2011-02-18 | GLAXOSMITHKLINE, PLC | 10% Owner | 普通株式 | 購入 | 152,278 | $23.70 |
| 2011-02-18 | YOUNG, WILLIAM D | Director | 普通株式 | 購入 | 10,752 | $8.53 |
| 2011-02-18 | YOUNG, WILLIAM D | Director | 普通株式 | 売却 | 5,376 | $23.22 |
| 2011-02-11 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 購入 | 27,500 | $0.00 |
| 2011-02-11 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 購入 | 220,000 | $0.00 |
| 2011-02-11 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 購入 | 100,000 | $0.00 |
| 2011-02-11 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 購入 | 12,500 | $0.00 |
| 2011-02-11 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 購入 | 100,000 | $0.00 |
| 2011-02-11 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 購入 | 12,500 | $0.00 |
| 2011-02-11 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 購入 | 50,000 | $0.00 |
| 2011-02-11 | BLUM, LEONARD M | Sr VP, Chief Comm. Officer | 普通株式 | 購入 | 12,500 | $0.00 |
| 2011-02-11 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | 普通株式 | 購入 | 100,000 | $0.00 |
| 2011-02-11 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | 普通株式 | 購入 | 12,500 | $0.00 |
| 2011-02-11 | BLUM, LEONARD M | Sr VP, Chief Comm. Officer | 普通株式 | 購入 | 100,000 | $0.00 |
| 2011-02-11 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 購入 | 12,500 | $0.00 |
| 2011-01-28 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 購入 | 9,838 | $8.53 |
| 2011-01-28 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | ストックオプション | 売却 | 3,387 | $0.00 |
| 2011-01-28 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | ストックオプション | 売却 | 6,451 | $0.00 |
| 2010-12-22 | DRAZAN, JEFFREY M | Director | 普通株式 | 購入 | 63,729 | $0.00 |
| 2010-12-22 | LEVINE, ARNOLD J | Director | 普通株式 | 購入 | 768 | $0.00 |
| 2010-12-22 | DRAZAN, JEFFREY M | Director | 普通株式 | 売却 | 2,688,754 | $0.00 |
| 2010-12-22 | DRAZAN, JEFFREY M | Director | 普通株式 | 売却 | 59,040 | $0.00 |
| 2010-12-22 | WHITESIDES, GEORGE M | Director | 普通株式 | 購入 | 1,152 | $0.00 |
| 2010-12-22 | GUNDERSON, ROBERT V JR | Director | 普通株式 | 購入 | 768 | $0.00 |
| 2010-12-10 | YOUNG, WILLIAM D | Director | ストックオプション | 売却 | 10,754 | $0.00 |
| 2010-12-10 | YOUNG, WILLIAM D | Director | 普通株式 | 売却 | 5,377 | $26.64 |
| 2010-12-10 | YOUNG, WILLIAM D | Director | 普通株式 | 購入 | 10,754 | $8.53 |
| 2010-12-03 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | 普通株式 | 売却 | 10,000 | $26.51 |
| 2010-12-01 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 購入 | 15,275 | $3.10 |
| 2010-12-01 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 売却 | 20,000 | $25.07 |
| 2010-12-01 | BRINKLEY, DAVID L | Head of Business Dev. | ストックオプション | 売却 | 15,275 | $0.00 |
| 2010-11-29 | GLAXOSMITHKLINE, PLC | 10% Owner | 普通株式 | 購入 | 5,750,000 | $22.50 |
| 2010-11-20 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 2,403 | $22.52 |
| 2010-11-20 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | 普通株式 | 売却 | 2,814 | $22.52 |
| 2010-11-20 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 売却 | 5,555 | $22.52 |
| 2010-11-20 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 売却 | 2,532 | $22.52 |
| 2010-11-20 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 売却 | 1,767 | $22.52 |
| 2010-10-26 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | 普通株式 | 購入 | 12,500 | $0.00 |
| 2010-10-26 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 購入 | 12,500 | $0.00 |
| 2010-10-26 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 購入 | 12,500 | $0.00 |
| 2010-10-26 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 購入 | 12,500 | $0.00 |
| 2010-10-26 | BLUM, LEONARD M | Sr VP, Chief Comm. Officer | 普通株式 | 購入 | 12,500 | $0.00 |
| 2010-10-26 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 購入 | 27,500 | $0.00 |
| 2010-10-20 | FORE, HENRIETTA | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2010-10-20 | FORE, HENRIETTA | Director | ストックオプション | 購入 | 3,000 | $0.00 |
| 2010-10-20 | FORE, HENRIETTA | Director | 普通株式 | 購入 | 3,000 | $0.00 |
| 2010-10-20 | FORE, HENRIETTA | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2010-09-14 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 売却 | 1,980 | $15.12 |
| 2010-09-07 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 購入 | 6,451 | $8.53 |
| 2010-09-07 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | ストックオプション | 売却 | 6,451 | $0.00 |
| 2010-09-01 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 売却 | 4,416 | $12.84 |
| 2010-08-20 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 1,543 | $14.00 |
| 2010-08-20 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 売却 | 1,671 | $14.00 |
| 2010-08-20 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 売却 | 907 | $14.00 |
| 2010-08-20 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 売却 | 3,624 | $14.00 |
| 2010-08-20 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | 普通株式 | 売却 | 1,955 | $14.00 |
| 2010-06-17 | LEVINE, ARNOLD J | Director | 普通株式 | 購入 | 29,192 | $0.00 |
| 2010-06-15 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 購入 | 33,516 | $8.53 |
| 2010-06-15 | BRINKLEY, DAVID L | Head of Business Dev. | ストックオプション | 売却 | 33,516 | $0.00 |
| 2010-06-15 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 売却 | 33,516 | $15.45 |
| 2010-06-14 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 購入 | 33,516 | $8.53 |
| 2010-06-14 | BRINKLEY, DAVID L | Head of Business Dev. | ストックオプション | 売却 | 33,516 | $0.00 |
| 2010-06-14 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 売却 | 33,516 | $15.65 |
| 2010-05-20 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 売却 | 908 | $13.02 |
| 2010-05-20 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 売却 | 1,673 | $13.02 |
| 2010-05-20 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 売却 | 3,625 | $13.02 |
| 2010-05-20 | BLUM, LEONARD M | Sr VP, Chief Comm. Officer | 普通株式 | 売却 | 1,686 | $13.02 |
| 2010-05-20 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | 普通株式 | 売却 | 1,955 | $13.02 |
| 2010-05-20 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 1,544 | $13.02 |
| 2010-04-27 | MALKIEL, BURTON G | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2010-04-27 | MALKIEL, BURTON G | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2010-04-27 | LEVINE, ARNOLD J | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2010-04-27 | LEVINE, ARNOLD J | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2010-04-27 | GUNDERSON, ROBERT V JR | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2010-04-27 | RINGROSE, PETER S | Director | 普通株式 | 購入 | 12,000 | $0.00 |
| 2010-04-27 | YOUNG, WILLIAM D | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2010-04-27 | WHITESIDES, GEORGE M | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2010-04-27 | WHITESIDES, GEORGE M | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2010-04-27 | WALTRIP, WILLIAM H | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2010-04-27 | WALTRIP, WILLIAM H | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2010-04-27 | GUNDERSON, ROBERT V JR | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2010-04-27 | DRAZAN, JEFFREY M | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2010-04-27 | YOUNG, WILLIAM D | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2010-04-27 | DRAZAN, JEFFREY M | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2010-02-25 | WALTRIP, WILLIAM H | Director | 普通株式 | 購入 | 32,258 | $8.53 |
| 2010-02-25 | WALTRIP, WILLIAM H | Director | ストックオプション | 売却 | 32,258 | $0.00 |
| 2010-02-25 | BLUM, LEONARD M | Sr VP, Chief Comm. Officer | 普通株式 | 購入 | 677 | $10.33 |
| 2010-02-24 | BLUM, LEONARD M | Sr VP, Chief Comm. Officer | 普通株式 | 購入 | 12,025 | $10.48 |
| 2010-02-20 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | 普通株式 | 売却 | 1,657 | $10.22 |
| 2010-02-20 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 売却 | 1,318 | $10.22 |
| 2010-02-20 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 1,163 | $10.22 |
| 2010-02-20 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 売却 | 2,413 | $10.22 |
| 2010-02-20 | BLUM, LEONARD M | Sr VP, Chief Comm. Officer | 普通株式 | 売却 | 1,335 | $10.22 |
| 2010-02-20 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 売却 | 401 | $10.22 |
| 2010-02-10 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 購入 | 25,000 | $0.00 |
| 2010-02-10 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 購入 | 25,000 | $0.00 |
| 2010-02-10 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 購入 | 25,000 | $0.00 |
| 2010-02-10 | BLUM, LEONARD M | Sr VP, Chief Comm. Officer | 普通株式 | 購入 | 25,000 | $0.00 |
| 2010-02-10 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | 普通株式 | 購入 | 25,000 | $0.00 |
| 2010-02-10 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 購入 | 55,000 | $0.00 |
| 2009-12-23 | VAGELOS, P ROY | Director | ストックオプション | 売却 | 200,000 | $0.00 |
| 2009-12-23 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 200,000 | $8.53 |
| 2009-12-16 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 売却 | 1,956 | $13.01 |
| 2009-11-20 | BLUM, LEONARD M | Sr VP, Chief Comm. Officer | 普通株式 | 売却 | 1,114 | $14.04 |
| 2009-11-20 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 売却 | 2,364 | $14.04 |
| 2009-11-20 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 971 | $14.04 |
| 2009-11-20 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 売却 | 1,100 | $14.04 |
| 2009-11-20 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 売却 | 704 | $14.04 |
| 2009-11-20 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | 普通株式 | 売却 | 1,382 | $14.04 |
| 2009-09-15 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 売却 | 9,000 | $17.86 |
| 2009-09-15 | BRINKLEY, DAVID L | Head of Business Dev. | ストックオプション | 売却 | 9,000 | $0.00 |
| 2009-09-15 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 購入 | 9,000 | $8.53 |
| 2009-09-13 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | 普通株式 | 売却 | 4,468 | $18.20 |
| 2009-08-20 | BRINKLEY, DAVID L | Head of Business Dev. | 普通株式 | 売却 | 206 | $15.65 |
| 2009-08-20 | BLUM, LEONARD M | Sr VP, Chief Comm. Officer | 普通株式 | 売却 | 1,084 | $15.65 |
| 2009-08-20 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | 普通株式 | 売却 | 1,347 | $15.65 |
| 2009-08-20 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 946 | $15.65 |
| 2009-08-20 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 売却 | 1,071 | $15.65 |
| 2009-08-20 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 売却 | 2,303 | $15.65 |
| 2009-05-20 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 946 | $14.06 |
| 2009-05-20 | MAMMEN, MATHAI | SVP, Research & Early Clin Dev | 普通株式 | 売却 | 1,071 | $14.06 |
| 2009-05-20 | BLUM, LEONARD M | Sr VP, Chief Comm. Officer | 普通株式 | 売却 | 1,086 | $14.06 |
| 2009-05-20 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | 普通株式 | 売却 | 1,347 | $14.06 |
| 2009-05-20 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 売却 | 2,303 | $14.06 |
| 2009-04-24 | GUNDERSON, ROBERT V JR | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2009-04-24 | MALKIEL, BURTON G | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2009-04-24 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 25,000 | $0.00 |
| 2009-04-24 | YOUNG, WILLIAM D | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2009-04-24 | YOUNG, WILLIAM D | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2009-04-24 | WHITESIDES, GEORGE M | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2009-04-24 | WHITESIDES, GEORGE M | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2009-04-24 | WALTRIP, WILLIAM H | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2009-04-24 | WALTRIP, WILLIAM H | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2009-04-24 | MALKIEL, BURTON G | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2009-04-24 | LEVINE, ARNOLD J | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2009-04-24 | LEVINE, ARNOLD J | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2009-04-24 | GUNDERSON, ROBERT V JR | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2009-04-24 | DRAZAN, JEFFREY M | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2009-04-24 | DRAZAN, JEFFREY M | Director | ストックオプション | 購入 | 6,000 | $0.00 |
| 2009-03-20 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | 普通株式 | 購入 | 37,000 | $0.00 |
| 2009-03-20 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 購入 | 37,000 | $0.00 |
| 2009-03-20 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 購入 | 80,000 | $0.00 |
| 2009-03-20 | MAMMEN, MATHAI | Senior VP, Research | 普通株式 | 購入 | 37,000 | $0.00 |
| 2009-03-20 | BLUM, LEONARD M | Sr VP, Chief Comm. Officer | 普通株式 | 購入 | 35,000 | $0.00 |
| 2009-03-06 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 購入 | $99,750.00 | |
| 2009-02-20 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | 普通株式 | 売却 | 2,370 | $14.87 |
| 2009-02-20 | MAMMEN, MATHAI | Senior VP, Research | 普通株式 | 売却 | 1,183 | $14.87 |
| 2009-02-20 | BLUM, LEONARD M | Sr VP, Chief Comm. Officer | 普通株式 | 売却 | 1,461 | $14.87 |
| 2009-02-20 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 売却 | 2,108 | $14.87 |
| 2009-02-20 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 578 | $14.87 |
| 2008-07-30 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 34,676 | $15.97 |
| 2008-07-23 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | ストックオプション | 購入 | 60,000 | $0.00 |
| 2008-07-23 | BLUM, LEONARD M | Sr VP, Chief Comm. Officer | ストックオプション | 購入 | 30,000 | $0.00 |
| 2008-06-04 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 600 | $13.06 |
| 2008-06-04 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 購入 | 15,000 | $8.53 |
| 2008-06-04 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 140 | $13.07 |
| 2008-06-04 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 800 | $13.05 |
| 2008-06-04 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 1,400 | $13.04 |
| 2008-06-04 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 3,200 | $13.01 |
| 2008-06-04 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 8,860 | $13.00 |
| 2008-06-04 | KITT, MICHAEL | Sr. Vice President Development | ストックオプション | 売却 | 15,000 | $0.00 |
| 2008-06-03 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 100 | $13.08 |
| 2008-06-03 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 300 | $13.07 |
| 2008-06-03 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 200 | $13.06 |
| 2008-06-03 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 300 | $13.05 |
| 2008-06-03 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 200 | $13.00 |
| 2008-06-03 | KITT, MICHAEL | Sr. Vice President Development | ストックオプション | 売却 | 655 | $0.00 |
| 2008-06-03 | KITT, MICHAEL | Sr. Vice President Development | ストックオプション | 売却 | 645 | $0.00 |
| 2008-06-03 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 購入 | 655 | $3.10 |
| 2008-06-03 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 購入 | 645 | $8.53 |
| 2008-06-03 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 100 | $13.08 |
| 2008-06-03 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 100 | $13.07 |
| 2008-06-02 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 200 | $13.03 |
| 2008-06-02 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 購入 | 3,700 | $3.10 |
| 2008-06-02 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 2,150 | $13.00 |
| 2008-06-02 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 1,350 | $13.01 |
| 2008-06-02 | KITT, MICHAEL | Sr. Vice President Development | ストックオプション | 売却 | 3,700 | $0.00 |
| 2008-04-22 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 28,898 | $0.00 |
| 2008-04-22 | YOUNG, WILLIAM D | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2008-04-22 | LEVINE, ARNOLD J | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2008-04-22 | GUNDERSON, ROBERT V JR | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2008-04-22 | WHITESIDES, GEORGE M | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2008-04-22 | WALTRIP, WILLIAM H | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2008-04-22 | MALKIEL, BURTON G | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2008-04-22 | DRAZAN, JEFFREY M | Director | 普通株式 | 購入 | 6,000 | $0.00 |
| 2008-03-14 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 886 | $10.27 |
| 2008-03-14 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 2,000 | $10.22 |
| 2008-03-14 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 800 | $10.21 |
| 2008-03-14 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 500 | $10.19 |
| 2008-03-14 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 200 | $10.19 |
| 2008-03-14 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 1,100 | $10.18 |
| 2008-03-14 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 300 | $10.17 |
| 2008-03-14 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 100 | $10.15 |
| 2008-03-14 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 400 | $10.14 |
| 2008-03-14 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 100 | $10.14 |
| 2008-03-14 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 400 | $10.13 |
| 2008-03-14 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 1,000 | $10.30 |
| 2008-03-14 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 3,120 | $10.24 |
| 2008-03-14 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 600 | $10.29 |
| 2008-03-14 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 100 | $10.29 |
| 2008-03-14 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 1,300 | $10.28 |
| 2008-03-14 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 400 | $10.24 |
| 2008-03-14 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 3,800 | $10.23 |
| 2008-03-14 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 500 | $10.23 |
| 2008-03-14 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 3,194 | $10.25 |
| 2008-03-14 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 100 | $10.28 |
| 2008-03-14 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 200 | $10.20 |
| 2008-03-14 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 1,600 | $10.20 |
| 2008-03-14 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 2,300 | $10.26 |
| 2008-03-13 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 4,600 | $10.56 |
| 2008-03-13 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 100 | $10.45 |
| 2008-03-13 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 1,300 | $10.46 |
| 2008-03-13 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 1,046 | $10.47 |
| 2008-03-13 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 2,554 | $10.48 |
| 2008-03-13 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 300 | $10.49 |
| 2008-03-13 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 100 | $10.50 |
| 2008-03-13 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 1,000 | $10.51 |
| 2008-03-13 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 1,700 | $10.52 |
| 2008-03-13 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 600 | $10.53 |
| 2008-03-13 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 1,500 | $10.54 |
| 2008-03-13 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 3,800 | $10.55 |
| 2008-03-13 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 2,600 | $10.57 |
| 2008-03-13 | VAGELOS, P ROY | Director | 普通株式 | 購入 | 2,800 | $10.58 |
| 2008-03-11 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 購入 | 3,600 | $10.46 |
| 2008-03-11 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 購入 | 11,457 | $10.50 |
| 2008-03-11 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 購入 | 2,729 | $10.40 |
| 2008-03-11 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 購入 | 1,000 | $10.41 |
| 2008-03-11 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 購入 | 414 | $10.42 |
| 2008-03-11 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 購入 | 100 | $10.43 |
| 2008-03-11 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 購入 | 500 | $10.44 |
| 2008-03-11 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 購入 | 200 | $10.49 |
| 2008-03-10 | BLUM, LEONARD M | Sr VP, Chief Comm. Officer | 普通株式 | 購入 | 2,385 | $9.97 |
| 2008-03-10 | BLUM, LEONARD M | Sr VP, Chief Comm. Officer | 普通株式 | 購入 | 26,000 | $10.92 |
| 2008-01-29 | WINNINGHAM, RICK E | Director, Chief Executive Officer | 普通株式 | 購入 | 23,118 | $0.00 |
| 2008-01-29 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | 普通株式 | 購入 | 23,333 | $0.00 |
| 2008-01-29 | BLUM, LEONARD M | Sr VP, Chief Comm. Officer | 普通株式 | 購入 | 13,611 | $0.00 |
| 2008-01-29 | CAMPBELL, ARTHUR L | Sr. VP, Technical Operations | 普通株式 | 購入 | 5,376 | $0.00 |
| 2008-01-29 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 購入 | 5,376 | $0.00 |
| 2008-01-29 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 購入 | 5,376 | $0.00 |
| 2008-01-29 | MAMMEN, MATHAI | Senior VP, Research | ストックオプション | 購入 | 100,000 | $0.00 |
| 2008-01-29 | MAMMEN, MATHAI | Senior VP, Research | 普通株式 | 購入 | 11,000 | $0.00 |
| 2008-01-17 | DRAZAN, JEFFREY M | Director | 普通株式 | 購入 | 3,193,000 | $3,193,000.00 |
| 2008-01-17 | DRAZAN, JEFFREY M | Director | 普通株式 | 購入 | $307,000.00 | |
| 2008-01-17 | DRAZAN, JEFFREY M | Director | 普通株式 | 購入 | $3,193,000.00 | |
| 2008-01-17 | DRAZAN, JEFFREY M | Director | 普通株式 | 購入 | 307,000 | $307,000.00 |
| 2007-12-14 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 300 | $22.70 |
| 2007-12-14 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 125 | $22.79 |
| 2007-12-14 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 14 | $23.00 |
| 2007-12-14 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 203 | $22.56 |
| 2007-12-14 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 100 | $22.57 |
| 2007-12-14 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 300 | $22.60 |
| 2007-12-14 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 100 | $22.61 |
| 2007-12-14 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 300 | $22.62 |
| 2007-12-14 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 100 | $22.63 |
| 2007-12-14 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 900 | $22.65 |
| 2007-12-14 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 100 | $22.78 |
| 2007-12-14 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 700 | $22.50 |
| 2007-12-14 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 600 | $22.52 |
| 2007-12-14 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 497 | $22.53 |
| 2007-12-14 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 100 | $22.54 |
| 2007-12-10 | HUMPHREY, PATRICK PA | Executive VP Research | 普通株式 | 購入 | 32,258 | $3.10 |
| 2007-12-10 | HUMPHREY, PATRICK PA | Executive VP Research | 普通株式 | 購入 | 10,323 | $9.69 |
| 2007-12-10 | HUMPHREY, PATRICK PA | Executive VP Research | 普通株式 | 購入 | 11,729 | $8.53 |
| 2007-12-10 | HUMPHREY, PATRICK PA | Executive VP Research | ストックオプション | 売却 | 10,323 | $0.00 |
| 2007-12-10 | HUMPHREY, PATRICK PA | Executive VP Research | ストックオプション | 売却 | 11,729 | $0.00 |
| 2007-12-10 | HUMPHREY, PATRICK PA | Executive VP Research | ストックオプション | 売却 | 32,258 | $0.00 |
| 2007-10-31 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 25,000 | $25.00 |
| 2007-09-27 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 購入 | 833 | $0.00 |
| 2007-09-14 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 122 | $27.61 |
| 2007-09-14 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 401 | $27.64 |
| 2007-09-14 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 100 | $27.65 |
| 2007-09-14 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 100 | $27.66 |
| 2007-09-14 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 300 | $27.67 |
| 2007-09-14 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 299 | $27.68 |
| 2007-09-14 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 100 | $27.75 |
| 2007-09-14 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 300 | $27.73 |
| 2007-09-14 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 200 | $27.72 |
| 2007-09-14 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 100 | $27.70 |
| 2007-09-14 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 101 | $27.69 |
| 2007-09-14 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 100 | $27.55 |
| 2007-09-14 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 200 | $27.56 |
| 2007-09-14 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 100 | $27.57 |
| 2007-09-14 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 100 | $27.58 |
| 2007-09-14 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 100 | $27.63 |
| 2007-09-14 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 100 | $27.51 |
| 2007-09-14 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 500 | $27.79 |
| 2007-09-14 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 100 | $27.78 |
| 2007-09-14 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 100 | $27.53 |
| 2007-09-14 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 100 | $27.54 |
| 2007-09-13 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | 普通株式 | 売却 | 8,937 | $28.00 |
| 2007-08-23 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 9,500 | $30.00 |
| 2007-08-23 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 500 | $30.02 |
| 2007-08-23 | KITT, MICHAEL | Sr. Vice President Development | ストックオプション | 売却 | 10,000 | $0.00 |
| 2007-08-23 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 購入 | 10,000 | $8.53 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 100 | $26.62 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 452 | $25.87 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 600 | $25.86 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 300 | $25.73 |
| 2007-08-01 | BLUM, LEONARD M | Sr VP, Chief Comm. Officer | 普通株式 | 購入 | 50,000 | $0.00 |
| 2007-08-01 | BLUM, LEONARD M | Sr VP, Chief Comm. Officer | ストックオプション | 購入 | 175,000 | $0.00 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 827 | $25.99 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 300 | $25.98 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 1,000 | $25.95 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 1,400 | $25.94 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 300 | $25.92 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 2,048 | $25.90 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 1,300 | $25.89 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 200 | $25.84 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 400 | $25.83 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 600 | $25.82 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 300 | $25.71 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 100 | $25.68 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 200 | $25.67 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 400 | $25.66 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 100 | $25.63 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 200 | $25.61 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 100 | $25.57 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 100 | $25.55 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 500 | $25.97 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 1,673 | $25.96 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 500 | $25.93 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 400 | $25.91 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 700 | $25.88 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 200 | $25.85 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 100 | $25.81 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 500 | $25.80 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 900 | $25.79 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 100 | $25.78 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 100 | $25.77 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 300 | $25.76 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 500 | $25.75 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 100 | $26.60 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 100 | $26.59 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 100 | $26.52 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 100 | $26.49 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 400 | $26.67 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 200 | $26.66 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 100 | $26.64 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 100 | $26.63 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 200 | $26.55 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 200 | $26.54 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 200 | $26.48 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 500 | $26.46 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 100 | $26.33 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 100 | $26.32 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 400 | $26.30 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 300 | $26.29 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 100 | $26.28 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 100 | $26.26 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 200 | $26.24 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 100 | $26.03 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 600 | $26.02 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 1,000 | $26.01 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 1,600 | $26.00 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 100 | $26.44 |
| 2007-08-01 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 売却 | 200 | $26.38 |
| 2007-07-03 | MALKIEL, BURTON G | Director | ストックオプション | 購入 | 30,000 | $0.00 |
| 2007-06-15 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 100 | $33.60 |
| 2007-06-15 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 83 | $33.49 |
| 2007-06-15 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 100 | $33.54 |
| 2007-06-15 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 1,000 | $33.55 |
| 2007-06-15 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 40 | $33.70 |
| 2007-06-15 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 922 | $33.50 |
| 2007-06-15 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 241 | $33.65 |
| 2007-06-15 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 300 | $33.69 |
| 2007-06-15 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 200 | $33.56 |
| 2007-05-21 | WHITESIDES, GEORGE M | Director | 普通株式 | 売却 | 51,612 | $0.78 |
| 2007-04-25 | WHITESIDES, GEORGE M | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2007-04-25 | DRAZAN, JEFFREY M | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2007-04-25 | YOUNG, WILLIAM D | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2007-04-25 | GUNDERSON, ROBERT V JR | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2007-04-25 | VAGELOS, P ROY | Director | ストックオプション | 購入 | 86,694 | $0.00 |
| 2007-04-25 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | ストックオプション | 購入 | 16,129 | $0.00 |
| 2007-04-25 | WALTRIP, WILLIAM H | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2007-04-25 | SLATER, EVE ELIZABETH | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2007-04-25 | LEVINE, ARNOLD J | Director | ストックオプション | 購入 | 15,000 | $0.00 |
| 2007-04-25 | KITT, MICHAEL | Sr. Vice President Development | ストックオプション | 購入 | 16,129 | $0.00 |
| 2007-04-25 | CAMPBELL, ARTHUR L | Sr. VP, Technical Operations | ストックオプション | 購入 | 16,129 | $0.00 |
| 2007-04-25 | BRINKLEY, DAVID L | Sr. VP Commercial Development | ストックオプション | 購入 | 16,129 | $0.00 |
| 2007-04-25 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | ストックオプション | 購入 | 70,000 | $0.00 |
| 2007-04-25 | HUMPHREY, PATRICK PA | Executive VP Research | ストックオプション | 購入 | 33,870 | $0.00 |
| 2007-04-25 | WINNINGHAM, RICK E | Director, Chief Executive Officer | ストックオプション | 購入 | 69,355 | $0.00 |
| 2007-02-28 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 822 | $31.95 |
| 2007-02-28 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 2,178 | $31.93 |
| 2007-02-28 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 売却 | 100 | $31.94 |
| 2006-08-03 | DRAZAN, JEFFREY M | Director | 普通株式 | 購入 | 5 | $ |
| 2006-08-03 | DRAZAN, JEFFREY M | Director | 普通株式 | 購入 | 316 | $ |
| 2006-08-03 | DRAZAN, JEFFREY M | Director | 普通株式 | 購入 | 87 | $ |
| 2006-06-29 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 購入 | 2,686 | $3.10 |
| 2006-06-29 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 購入 | 5,322 | $3.10 |
| 2006-06-29 | KITT, MICHAEL | Sr. Vice President Development | ストックオプション | 売却 | 5,322 | $0.00 |
| 2006-06-29 | KITT, MICHAEL | Sr. Vice President Development | ストックオプション | 売却 | 2,686 | $0.00 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 100 | $24.57 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 200 | $24.50 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 100 | $24.18 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 300 | $24.17 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 100 | $24.16 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 100 | $24.06 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 100 | $24.04 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 100 | $24.03 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 300 | $24.05 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 200 | $24.05 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 300 | $24.03 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 300 | $24.02 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | ストックオプション | 購入 | 14,999 | $0.00 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 500 | $24.18 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 購入 | 14,999 | $3.10 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 100 | $24.50 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 100 | $24.66 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 100 | $24.58 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 100 | $24.14 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 400 | $24.14 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 129 | $24.14 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 300 | $24.15 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 100 | $24.02 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 200 | $24.12 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 2,819 | $24.12 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 300 | $24.13 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 100 | $24.13 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 961 | $24.12 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 100 | $24.11 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | ストックオプション | 売却 | 14,999 | $0.00 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 100 | $24.01 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 1,030 | $24.00 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 200 | $24.11 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 100 | $24.10 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 2,360 | $24.10 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 100 | $24.05 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 100 | $24.07 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 100 | $24.00 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 200 | $24.06 |
| 2006-06-09 | KITT, MICHAEL | Sr. Vice President Development | 普通株式 | 売却 | 100 | $24.12 |
| 2006-05-03 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 購入 | 29,032 | $3.10 |
| 2006-05-03 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | 普通株式 | 購入 | 11,729 | $8.53 |
| 2006-05-03 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | ストックオプション | 売却 | 29,032 | $0.00 |
| 2006-05-03 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | ストックオプション | 売却 | 11,729 | $0.00 |
| 2006-05-02 | LOEWENTHAL, RONN | Director | 普通株式 | 売却 | 100 | $28.64 |
| 2006-05-02 | LOEWENTHAL, RONN | Director | 普通株式 | 売却 | 300 | $28.51 |
| 2006-05-02 | LOEWENTHAL, RONN | Director | 普通株式 | 売却 | 100 | $28.55 |
| 2006-05-02 | LOEWENTHAL, RONN | Director | 普通株式 | 売却 | 1,100 | $28.64 |
| 2006-05-02 | LOEWENTHAL, RONN | Director | 普通株式 | 売却 | 800 | $28.64 |
| 2006-05-02 | LOEWENTHAL, RONN | Director | 普通株式 | 売却 | 500 | $28.64 |
| 2006-05-02 | LOEWENTHAL, RONN | Director | 普通株式 | 売却 | 1,245 | $27.75 |
| 2006-05-02 | LOEWENTHAL, RONN | Director | 普通株式 | 売却 | 5,400 | $27.90 |
| 2006-05-02 | LOEWENTHAL, RONN | Director | 普通株式 | 購入 | 10,645 | $8.53 |
| 2006-05-02 | LOEWENTHAL, RONN | Director | 普通株式 | 売却 | 100 | $28.62 |
| 2006-05-02 | LOEWENTHAL, RONN | Director | ストックオプション | 売却 | 4,000 | $0.00 |
| 2006-05-02 | LOEWENTHAL, RONN | Director | ストックオプション | 売却 | 6,645 | $0.00 |
| 2006-05-02 | LOEWENTHAL, RONN | Director | 普通株式 | 売却 | 100 | $28.39 |
| 2006-05-02 | LOEWENTHAL, RONN | Director | 普通株式 | 売却 | 100 | $28.43 |
| 2006-05-02 | LOEWENTHAL, RONN | Director | 普通株式 | 売却 | 100 | $28.46 |
| 2006-04-26 | GUNDERSON, ROBERT V JR | Director | ストックオプション | 購入 | 12,903 | $0.00 |
| 2006-04-26 | LEVINE, ARNOLD J | Director | ストックオプション | 購入 | 12,903 | $0.00 |
| 2006-04-26 | WALTRIP, WILLIAM H | Director | ストックオプション | 購入 | 12,903 | $0.00 |
| 2006-04-26 | WHITESIDES, GEORGE M | Director | ストックオプション | 購入 | 12,903 | $0.00 |
| 2006-04-26 | DRAZAN, JEFFREY M | Director | ストックオプション | 購入 | 12,903 | $0.00 |
| 2006-04-26 | YOUNG, WILLIAM D | Director | ストックオプション | 購入 | 12,903 | $0.00 |
| 2006-04-26 | LOEWENTHAL, RONN | Director | ストックオプション | 購入 | 12,903 | $0.00 |
| 2006-04-26 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | ストックオプション | 購入 | 20,000 | $0.00 |
| 2006-04-26 | BAKER, JULIAN | Director | ストックオプション | 購入 | 12,903 | $0.00 |
| 2006-04-26 | SLATER, EVE ELIZABETH | Director | ストックオプション | 購入 | 12,903 | $0.00 |
| 2006-04-26 | VAGELOS, P ROY | Director | ストックオプション | 購入 | 86,694 | $0.00 |
| 2006-02-08 | WINNINGHAM, RICK E | Director, Chief Executive Officer | ストックオプション | 購入 | 69,355 | $0.00 |
| 2006-02-08 | SHAFER, BRADFORD J | Sr VP, Gen. Counsel, Secretary | ストックオプション | 購入 | 16,129 | $0.00 |
| 2006-02-08 | HUMPHREY, PATRICK PA | Executive VP Research | ストックオプション | 購入 | 33,870 | $0.00 |
| 2006-02-08 | AGUIAR, MICHAEL W | Sr VP, Chief Financial Officer | ストックオプション | 購入 | 30,250 | $0.00 |
| 2006-02-08 | BRINKLEY, DAVID L | Sr. VP Commercial Development | ストックオプション | 購入 | 16,129 | $0.00 |
| 2006-02-08 | CAMPBELL, ARTHUR L | Sr. VP, Technical Operations | ストックオプション | 購入 | 16,129 | $0.00 |
| 2006-02-08 | KITT, MICHAEL | Sr. Vice President Development | ストックオプション | 購入 | 16,129 | $0.00 |
| 2006-01-05 | DRAZAN, JEFFREY M | Director | 普通株式 | 購入 | 505 | $ |
| 2005-12-31 | DRAZAN, JEFFREY M | Director | 普通株式 | 購入 | 281 | $ |
| 2005-12-31 | DRAZAN, JEFFREY M | Director | 普通株式 | 購入 | 953 | $ |
| 2005-12-31 | DRAZAN, JEFFREY M | Director | 普通株式 | 購入 | 15 | $ |
| 2005-12-28 | DRAZAN, JEFFREY M | Director | 普通株式 | 購入 | 953 | $ |
| 2005-12-28 | DRAZAN, JEFFREY M | Director | 普通株式 | 購入 | 27 | $ |
| 2005-12-28 | DRAZAN, JEFFREY M | Director | 普通株式 | 購入 | 281 | $ |
| 2005-12-13 | BAKER, JULIAN | Director | 普通株式 | 売却 | 33,840 | $21.11 |
| 2005-12-08 | SLATER, EVE ELIZABETH | Director | ストックオプション | 購入 | 25,806 | $0.00 |
| 2005-09-07 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 購入 | 5,716 | $8.53 |
| 2005-09-07 | BRINKLEY, DAVID L | Sr. VP Commercial Development | ストックオプション | 売却 | 33,000 | $0.00 |
| 2005-09-07 | BRINKLEY, DAVID L | Sr. VP Commercial Development | ストックオプション | 売却 | 15,833 | $0.00 |
| 2005-09-07 | BRINKLEY, DAVID L | Sr. VP Commercial Development | ストックオプション | 売却 | 4,451 | $0.00 |
| 2005-09-07 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 購入 | 33,000 | $8.53 |
| 2005-09-07 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 購入 | 4,451 | $3.10 |
| 2005-09-07 | BRINKLEY, DAVID L | Sr. VP Commercial Development | 普通株式 | 購入 | 15,833 | $3.10 |
| 2005-09-07 | BRINKLEY, DAVID L | Sr. VP Commercial Development | ストックオプション | 売却 | 5,716 | $0.00 |
| 2005-06-30 | WALTRIP, WILLIAM H | Director | ストックオプション | 購入 | 12,903 | $0.00 |
| 2005-06-30 | DRAZAN, JEFFREY M | Director | ストックオプション | 購入 | 12,903 | $0.00 |
| 2005-06-30 | YOUNG, WILLIAM D | Director | ストックオプション | 購入 | 12,903 | $0.00 |
| 2005-06-30 | WHITESIDES, GEORGE M | Director | ストックオプション | 購入 | 12,903 | $0.00 |
| 2005-06-30 | LOEWENTHAL, RONN | Director | ストックオプション | 購入 | 12,903 | $0.00 |
| 2005-06-30 | LEVINE, ARNOLD J | Director | ストックオプション | 購入 | 12,903 | $0.00 |
| 2005-06-30 | BAKER, JULIAN | Director | ストックオプション | 購入 | 12,903 | $0.00 |
| 2005-06-30 | GUNDERSON, ROBERT V JR | Director | ストックオプション | 購入 | 12,903 | $0.00 |
| 2005-04-04 | DRAZAN, JEFFREY M | Director | 普通株式 | 購入 | 1,873 | $ |
| 2005-04-04 | DRAZAN, JEFFREY M | Director | 普通株式 | 購入 | 6,354 | $ |
| 2005-04-04 | DRAZAN, JEFFREY M | Director | 普通株式 | 購入 | 42 | $ |
| 2005-04-04 | DRAZAN, JEFFREY M | Director | 普通株式 | 購入 | 103 | $ |
| 2005-04-04 | DRAZAN, JEFFREY M | Director | 普通株式 | 購入 | 6,354 | $ |
| 2005-04-04 | DRAZAN, JEFFREY M | Director | 普通株式 | 購入 | 1,873 | $ |
| 2005-04-01 | DRAZAN, JEFFREY M | Director | 普通株式 | 購入 | 3,609 | $ |
| 2005-04-01 | DRAZAN, JEFFREY M | Director | 普通株式 | 購入 | 1,046 | $ |
| 2005-04-01 | DRAZAN, JEFFREY M | Director | 普通株式 | 購入 | 3,609 | $ |
| 2005-04-01 | DRAZAN, JEFFREY M | Director | 普通株式 | 購入 | 1,046 | $ |
| 2005-04-01 | DRAZAN, JEFFREY M | Director | 普通株式 | 購入 | 57 | $ |
| 2005-04-01 | DRAZAN, JEFFREY M | Director | 普通株式 | 購入 | 24 | $ |
売上・収益性
売上高（直近12ヶ月）
$38,852万ドル
一株あたり売上高（直近12ヶ月）
$6.04
売上総利益（直近12ヶ月）
$32,834万ドル
営業利益（EBITDA：減価償却前）
$20,000万ドル
利益率
32.8%
営業利益率（直近12ヶ月）
32.1%
配当・収入
配当金額（1株あたり）
$None
配当利回り
0%
支払日
2015-09-30
権利落ち日
2015-09-08
バリュエーション指標
株価収益率（PER）
13.37倍
実績PER
13.37倍
予想PER
11.71倍
株価収益成長率（PEG）
0.335
株価売上高倍率（直近12ヶ月）
4.081倍
株価純資産倍率 (PBR)
1.43倍
1株当たり純資産（BPS）
$13.51
企業価値倍率（EV）
EV/売上高倍率
3.355倍
EV/EBITDA倍率
3.731倍
投資リターン
総資産利益率（直近12ヶ月）
8.16%
自己資本利益率（直近12ヶ月）
15.2%
リターン分析
| 日数 | リターンレンジ | リターン中央値 | 累積リターン | 分散（バリアンス） | 標準偏差 | 最大下落率 | 最大下落期間 | SPYとの相関係数 | ||
|---|---|---|---|---|---|---|---|---|---|---|
| 15日間 | -1.8182% | 2.4555% | 0.678% | 2.6609% | 0.0001833172241129203 | 0.013539469122270649 | -1.8182% | 1日 | -0.17096448785672932 | |
| 30日間 | -1.8182% | 3.0566% | 0.391% | 6.5463% | 0.00017327625593305934 | 0.013163443923725255 | -2.439% | 2日 | -0.08219406743046967 | |
| 90日間 | -2.8878% | 5.0661% | 0.2644% | 19.4332% | 0.00026054386062150913 | 0.016141371088650096 | -8.0033% | 6日 | -0.042269174564845635 |
損益計算書
会計期末日
2025-12-31
報告通貨
USD
売上高・粗利益
売上原価
営業経費
営業利益・税引前指標
売上高
$425,128,000
粗利益
$307,516,000
売上コスト
$117,612,000
商品・サービス原価
$117,612,000
販売管理費
$113,318,000
研究開発
$30,604,000
運営コスト
$143,771,000
減価償却
$None
減価償却・償却費
$40,228,000
営業利益
$163,745,000
営業利益EBIT
$343,560,000
償却前営業利益EBITA
$383,788,000
税引前利益
$326,862,000
利息・投資・その他営業外項目
税金関連
当期純・包括利益
純投資収益
$None
純金利収入
$4,388,000
利息収入
$21,086,000
金利コスト
$16,698,000
利息・債務コスト
$None
非利息収益
$None
営業外収益（その他）
$None
法人税等
$55,697,000
継続事業純利益
$271,165,000
純利益
$271,165,000
税引後包括利益
$None
貸借対照表
会計期末日
2025-12-31
報告通貨
USD
総資産
$1,635,165,000
現金及び現金同等物
$550,941,000
現金及び短期投資
$550,941,000
短期投資
$15,727,000
在庫資産
$39,172,000
流動売掛金（純額）
$34,966,000
その他流動資産
$102,436,000
流動資産合計
$727,515,000
有形固定資産
$None
減価償却累計額（PPE）
$None
無形資産
$182,156,000
無形資産（のれん除く）
$182,156,000
のれん（無形資産）
$17,905,000
投資
$None
長期投資
$598,223,000
その他固定資産
$None
固定資産合計
$907,650,000
総負債
$462,324,000
買掛金（短期）
$4,966,000
前受金
$None
流動債務
$None
短期借入金
$418,000
固定長期負債
$None
その他流動負債
$39,768,000
流動負債合計
$49,696,000
リース債務
$11,286,000
長期債務
$257,731,000
長期債務（流動外）
$None
短期・長期借入金合計
$269,017,000
その他固定負債
$1,119,000
固定負債合計
$412,628,000
純資産
$1,172,841,000
自己株式（金庫株）
$None
利益剰余金
$269,368,000
普通株式
$747,000
発行済株式数（普通株）
$84,760,000
キャッシュフロー計算書
会計期末日
2025-12-31
報告通貨
USD
損益計算・収益性
営業活動
投資活動
損益
$None
純利益
$271,165,000
営業キャッシュフロー
$196,930,000
営業活動による支払い
$None
営業活動によるキャッシュフロー
$None
営業活動に関連する負債の増減額
$None
営業活動に関連する資産の増減額
$None
売掛金の増減額
$None
在庫資産の増減額
-$12,919,000
減価償却・減耗費・償却費
$40,228,000
投資活動によるキャッシュフロー
$40,496,000
設備投資
$1,131,000
財務活動
資金・為替照合
財務活動によるキャッシュフロー
$8,551,000
短期融資回収金
$None
自社株買い支出（普通株）
$None
自社株買い支出（優先株）
$None
自社株買い支出
$None
配当支払い（普通株）
$None
配当支払い（優先株）
$None
配当支払い
$None
資金調達（普通株）
$None
資金調達（優先株）
$None
資金調達（長期債・資本証券）
$None
自社株売却による収益
$None
自社株再取得による収益
-$4,675,000
現金及び現金同等物の増減額
$None
為替レートの変動による増減額
$None
発行済株式数
広告パネル
スポンサー紹介
本物のネイティブ講師による
オンライン英会話DOJO
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