TXG

10X ジェノミクス

10X Genomics Inc

フォローする

株価・概要

$20.20

-1.17 (-5.4750%)

06:00AM 2026/04/30 (JST)

NASDAQ | USD

52週間レンジ

7.72

26.45

昨夜レンジ

19.53

21.48

前日終値

$21.37

出来高（数量）

2,709,949

ベータ値

2.172

50日移動平均値

$21.02

200日移動平均値

$16.71

1株あたりの利益（EPS）

-0.35

予想PER（株価収益率）

208.33

配当金

$None

配当利回り

インサイダー保有率

1.806%

機関投資家保有率

108.053%

TXG - 会社概要

10X Genomics, Inc.は、変革的なゲノム解析ソリューションを専門とする先進的なライフサイエンステクノロジー企業です。同社は、研究者が複雑な生物学的システムをこれまでにない詳細さで探究できるよう支援しています。本社はカリフォルニア州プレザントンにあり、最先端の機器、消耗品、解析ソフトウェアを幅広く提供し、遺伝子研究の精度と深さを向上させています。北米、ヨーロッパ、アジアに強固な拠点を持つ10X Genomicsは、ゲノム技術の発展に尽力しており、急速に進化する生物学研究と発見の分野で重要な役割を果たしています。同社の革新的な能力は、ライフサイエンス分野の多様なニーズに応える上で不可欠です。

セクター分類

ヘルスケア

業種

ヘルスケア (情報サービス)

時価総額（単位：万ドル）

$282,077

発行株式数（数量）

117,673,000

流通株数（数量）

115,325,000

本社住所

6230 STONERIDGE MALL ROAD, PLEASANTON, CA, UNITED STATES, 94588-3260

企業サイト

https://www.10xgenomics.com

会計年度終了

December

利益・成長性

1株あたりの利益（EPS）

-$0.35

希薄化後1株当たり利益EPS（直近12ヶ月）

-$0.35

四半期利益成長率（前年比）

0.0%

四半期売上成長率（前年比）

0.6%

アナリスト予想・評価

目標株価

$24.00

強気

買い

ホールド

売り

弱気

EPS（1株当たり純利益）

(): 予想EPS（アナリストたちの平均値）
	7日前	30日前	60日前	90日前		予想レンジ

配当履歴

権利落ち日	配当宣言日	権利確定日	配当金支払日	配当金額

株式分割

効力発生日	分割比率

インサイダーの売却・購入履歴

自社株取引日	役員・従業員名	役員・従業員の役職	株式の種類	売却／購入	株数	株価
2026-03-24	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	5,000	$19.52
2026-03-23	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	10,000	$19.13
2026-03-03	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	2,750	$0.00
2026-03-02	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	14,292	$22.67
2026-03-02	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	1,860	$23.18
2026-02-26	TAICH, ADAM	Chief Financial Officer	普通株式	購入	106,579	$0.00
2026-02-26	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	購入	157,895	$0.00
2026-02-26	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	購入	88,816	$0.00
2026-02-25	TEICHMANN, SARAH A.	Director	普通株式	売却	7,579	$19.41
2026-02-23	TAICH, ADAM	Chief Financial Officer	普通株式	売却	8,968	$18.58
2026-02-23	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	9,632	$18.58
2026-02-23	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	7,826	$18.58
2026-01-05	SAXONOV, SERGE	Director, Chief Executive Officer	ストックオプション	売却	17,463	$0.00
2026-01-05	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	購入	50,000	$1.20
2026-01-05	SAXONOV, SERGE	Director, Chief Executive Officer	ストックオプション	売却	32,537	$0.00
2025-11-24	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	13,261	$19.00
2025-11-24	TAICH, ADAM	Chief Financial Officer	普通株式	売却	11,888	$19.00
2025-11-24	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	8,283	$19.00
2025-09-12	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	900	$0.00
2025-08-22	TAICH, ADAM	Chief Financial Officer	普通株式	売却	22,315	$13.79
2025-08-22	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	7,486	$13.79
2025-08-22	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	9,348	$13.79
2025-06-09	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	1,000	$0.00
2025-06-03	STUELPNAGEL, JOHN R	Director	普通株式	購入	15,357	$0.00
2025-06-03	POPOVITS, KIMBERLY J	Director	普通株式	購入	15,357	$0.00
2025-06-03	MATEO, ALAN	Director	普通株式	購入	15,357	$0.00
2025-06-03	KOSARAJU, SRIDHAR	Director	普通株式	購入	15,357	$0.00
2025-06-03	SULIMAN, SHEHNAAZ	Director	普通株式	購入	15,357	$0.00
2025-06-03	TEICHMANN, SARAH A.	Director	普通株式	購入	15,357	$0.00
2025-05-29	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	3,000	$0.00
2025-05-22	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	9,343	$8.30
2025-05-22	TAICH, ADAM	Chief Financial Officer	普通株式	売却	4,044	$8.30
2025-05-22	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	7,485	$8.30
2025-03-17	TAICH, ADAM	Chief Financial Officer	普通株式	購入	133,928	$0.00
2025-03-17	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	購入	171,428	$0.00
2025-03-17	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	購入	120,535	$0.00
2025-03-04	SAXONOV, SERGE	Director, Chief Executive Officer	ストックオプション	売却	50,000	$0.00
2025-03-04	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	購入	50,000	$1.20
2025-02-28	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	7,942	$10.63
2025-02-24	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	5,092	$11.07
2025-02-24	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	4,573	$11.07
2025-02-21	MATEO, ALAN	Director	普通株式	購入	40,000	$11.14
2024-12-23	SAXONOV, SERGE	Director, Chief Executive Officer	ストックオプション	売却	12,000	$0.00
2024-12-23	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	購入	12,000	$1.20
2024-11-22	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	5,807	$13.69
2024-11-22	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	6,693	$13.69
2024-11-21	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	1,850	$0.00
2024-11-14	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	1,350	$0.00
2024-10-23	TAICH, ADAM	Chief Financial Officer	普通株式	購入	201,704	$0.00
2024-08-30	TEICHMANN, SARAH A.	Director	普通株式	購入	19,002	$0.00
2024-08-22	MCANEAR, JUSTIN J.	Former Chief Financial Officer	普通株式	売却	2,961	$22.53
2024-08-22	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	4,351	$22.53
2024-08-22	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	6,749	$22.53
2024-07-31	MATEO, ALAN	Director	普通株式	購入	21,691	$0.00
2024-06-11	KOSARAJU, SRIDHAR	Director	普通株式	購入	8,649	$0.00
2024-06-11	STUELPNAGEL, JOHN R	Director	普通株式	購入	8,649	$0.00
2024-06-11	POPOVITS, KIMBERLY J	Director	普通株式	購入	8,649	$0.00
2024-06-11	SULIMAN, SHEHNAAZ	Director	普通株式	購入	8,649	$0.00
2024-06-11	MAMMEN, MATHAI	Director	普通株式	購入	8,649	$0.00
2024-05-29	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	425	$0.00
2024-05-22	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	2,936	$24.30
2024-05-22	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	4,087	$24.30
2024-05-22	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	4,877	$24.30
2024-03-21	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	購入	88,854	$0.00
2024-03-21	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	購入	71,083	$0.00
2024-03-21	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	購入	53,312	$0.00
2024-03-14	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	1,086	$0.00
2024-03-04	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	4,660	$44.00
2024-02-22	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	2,821	$46.34
2024-02-22	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	2,613	$46.34
2024-02-22	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	1,865	$46.34
2024-02-15	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	3,300	$48.58
2024-02-15	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	1,700	$49.43
2024-02-09	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	1,000	$49.53
2024-01-16	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	2,965	$45.10
2024-01-16	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	1,035	$45.65
2023-12-28	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	購入	8,334	$11.48
2023-12-28	HINDSON, BENJAMIN J.	Director, See Remarks	ストックオプション	売却	8,334	$0.00
2023-12-27	SAXONOV, SERGE	Director, Chief Executive Officer	ストックオプション	売却	14,935	$0.00
2023-12-27	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	購入	14,935	$1.20
2023-12-14	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	1,700	$55.15
2023-12-14	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	300	$54.39
2023-11-24	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	3,723	$43.72
2023-11-22	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	1,679	$43.34
2023-11-22	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	3,757	$43.34
2023-11-22	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	3,449	$43.34
2023-11-22	WILBUR, JAMES	Chief Commercial Officer	普通株式	売却	3,464	$43.34
2023-11-20	WILBUR, JAMES	Chief Commercial Officer	普通株式	売却	14,718	$42.09
2023-11-14	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	2,000	$39.52
2023-10-17	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	1,979	$39.51
2023-10-16	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	21	$39.50
2023-09-14	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	3,167	$0.00
2023-09-14	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	1,920	$49.35
2023-09-14	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	80	$49.82
2023-08-22	WILBUR, JAMES	Chief Commercial Officer	普通株式	売却	9,699	$45.78
2023-08-22	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	1,678	$45.78
2023-08-22	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	3,449	$45.78
2023-08-22	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	3,757	$45.78
2023-08-14	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	17	$50.42
2023-08-14	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	1,983	$50.10
2023-08-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	1,727	$61.77
2023-08-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	5,243	$62.36
2023-08-01	HINDSON, BENJAMIN J.	Director, See Remarks	ストックオプション	売却	6,970	$0.00
2023-08-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	購入	6,970	$11.48
2023-07-19	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	40,000	$60.03
2023-07-19	HINDSON, BENJAMIN J.	Director, See Remarks	ストックオプション	売却	12,972	$0.00
2023-07-19	HINDSON, BENJAMIN J.	Director, See Remarks	ストックオプション	売却	968	$0.00
2023-07-19	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	購入	20,845	$5.04
2023-07-19	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	13,940	$60.03
2023-07-19	SAXONOV, SERGE	Director, Chief Executive Officer	ストックオプション	売却	20,845	$0.00
2023-07-19	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	購入	12,972	$5.04
2023-07-19	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	購入	968	$11.48
2023-07-14	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	1,149	$58.37
2023-07-14	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	851	$57.61
2023-06-14	KOSARAJU, SRIDHAR	Director	ストックオプション	購入	4,661	$0.00
2023-06-14	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	51	$59.15
2023-06-14	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	185	$0.00
2023-06-14	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	740	$57.50
2023-06-14	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	1,209	$58.53
2023-06-14	KOSARAJU, SRIDHAR	Director	普通株式	購入	1,865	$0.00
2023-06-14	ROBERTS, BRYAN E	Director	普通株式	購入	1,865	$0.00
2023-06-14	ROBERTS, BRYAN E	Director	ストックオプション	購入	4,661	$0.00
2023-06-14	SULIMAN, SHEHNAAZ	Director	普通株式	購入	1,865	$0.00
2023-06-14	SULIMAN, SHEHNAAZ	Director	ストックオプション	購入	4,661	$0.00
2023-06-14	STUELPNAGEL, JOHN R	Director	普通株式	購入	1,865	$0.00
2023-06-14	STUELPNAGEL, JOHN R	Director	ストックオプション	購入	4,661	$0.00
2023-06-14	MAMMEN, MATHAI	Director	普通株式	購入	1,865	$0.00
2023-06-14	POPOVITS, KIMBERLY J	Director	普通株式	購入	1,865	$0.00
2023-06-14	POPOVITS, KIMBERLY J	Director	ストックオプション	購入	4,661	$0.00
2023-06-14	MAMMEN, MATHAI	Director	ストックオプション	購入	4,661	$0.00
2023-06-05	STUELPNAGEL, JOHN R	Director	普通株式	売却	10,000	$54.89
2023-05-23	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	619	$55.06
2023-05-23	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	565	$55.06
2023-05-23	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	441	$55.06
2023-05-23	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	465	$55.06
2023-05-23	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	194	$55.07
2023-05-23	WILBUR, JAMES	Chief Commercial Officer	普通株式	売却	316	$55.07
2023-05-23	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	791	$55.06
2023-05-23	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	735	$55.06
2023-05-23	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	243	$55.06
2023-05-23	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	2,068	$55.06
2023-05-23	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	534	$55.06
2023-05-19	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	460	$0.00
2023-05-17	ROBERTS, BRYAN E	Director	普通株式	売却	3,790,422	$0.00
2023-05-17	ROBERTS, BRYAN E	Director	普通株式	購入	3,790,422	$0.00
2023-05-15	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	1,506	$53.57
2023-05-15	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	494	$52.70
2023-05-11	MAMMEN, MATHAI	Director	普通株式	売却	33,000	$52.82
2023-05-11	MAMMEN, MATHAI	Director	ストックオプション	売却	200,000	$0.00
2023-05-11	MAMMEN, MATHAI	Director	普通株式	購入	200,000	$1.16
2023-04-14	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	1,641	$53.61
2023-04-14	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	76	$55.28
2023-04-14	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	283	$54.64
2023-03-21	HINDSON, BENJAMIN J.	Director, See Remarks	ストックオプション	購入	36,387	$0.00
2023-03-21	WILBUR, JAMES	Chief Commercial Officer	譲渡制限付株式ユニット	購入	7,278	$0.00
2023-03-21	HINDSON, BENJAMIN J.	Director, See Remarks	譲渡制限付株式ユニット	購入	18,194	$0.00
2023-03-21	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	購入	25,991	$0.00
2023-03-21	MCANEAR, JUSTIN J.	Chief Financial Officer	ストックオプション	購入	25,991	$0.00
2023-03-21	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	購入	36,387	$0.00
2023-03-21	SAXONOV, SERGE	Director, Chief Executive Officer	ストックオプション	購入	72,773	$0.00
2023-03-21	SAXONOV, SERGE	Director, Chief Executive Officer	譲渡制限付株式ユニット	購入	72,773	$0.00
2023-03-21	WILBUR, JAMES	Chief Commercial Officer	普通株式	購入	14,555	$0.00
2023-03-21	MCANEAR, JUSTIN J.	Chief Financial Officer	譲渡制限付株式ユニット	購入	12,996	$0.00
2023-03-21	WILBUR, JAMES	Chief Commercial Officer	ストックオプション	購入	14,555	$0.00
2023-03-21	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	購入	36,387	$0.00
2023-03-14	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	303	$49.28
2023-03-14	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	1,697	$48.81
2023-03-07	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	260	$0.00
2023-02-22	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	1,941	$47.75
2023-02-22	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	1,742	$47.75
2023-02-22	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	1,245	$47.75
2022-12-14	HINDSON, BENJAMIN J.	Director, See Remarks	ストックオプション	売却	34,266	$0.00
2022-12-14	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	購入	34,266	$5.04
2022-12-13	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	1,740	$0.00
2022-12-12	SAXONOV, SERGE	Director, Chief Executive Officer	ストックオプション	売却	3,000	$0.00
2022-12-12	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	購入	3,000	$1.20
2022-11-22	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	288	$34.07
2022-11-22	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	686	$34.07
2022-11-22	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	1,087	$34.07
2022-11-22	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	915	$34.07
2022-11-22	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	789	$34.06
2022-11-22	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	1,887	$34.07
2022-11-22	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	359	$34.07
2022-11-22	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	652	$34.07
2022-09-14	WILBUR, JAMES	Chief Commercial Officer	普通株式	購入	95,839	$0.00
2022-09-14	KOSARAJU, SRIDHAR	Director	ストックオプション	売却	10,000	$0.00
2022-09-14	KOSARAJU, SRIDHAR	Director	普通株式	購入	10,000	$11.48
2022-09-14	WILBUR, JAMES	Chief Commercial Officer	ストックオプション	購入	239,596	$0.00
2022-09-14	HINDSON, BENJAMIN J.	Director, See Remarks	譲渡制限付株式ユニット	購入	67,655	$0.00
2022-09-14	HINDSON, BENJAMIN J.	Director, See Remarks	ストックオプション	購入	67,655	$0.00
2022-09-14	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	購入	33,828	$0.00
2022-09-14	MCANEAR, JUSTIN J.	Chief Financial Officer	譲渡制限付株式ユニット	購入	40,593	$0.00
2022-09-14	MCANEAR, JUSTIN J.	Chief Financial Officer	ストックオプション	購入	40,593	$0.00
2022-09-14	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	購入	20,297	$0.00
2022-09-14	SAXONOV, SERGE	Director, Chief Executive Officer	譲渡制限付株式ユニット	購入	213,112	$0.00
2022-09-14	SAXONOV, SERGE	Director, Chief Executive Officer	ストックオプション	購入	142,075	$0.00
2022-09-12	SAXONOV, SERGE	Director, Chief Executive Officer	ストックオプション	売却	11,500	$0.00
2022-09-12	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	購入	11,500	$1.20
2022-08-23	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	1,292	$35.19
2022-08-23	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	987	$35.19
2022-08-23	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	2,715	$35.19
2022-06-15	STUELPNAGEL, JOHN R	Director	普通株式	購入	2,120	$0.00
2022-06-15	MAMMEN, MATHAI	Director	普通株式	購入	2,120	$0.00
2022-06-15	SULIMAN, SHEHNAAZ	Director	ストックオプション	購入	5,300	$0.00
2022-06-15	STUELPNAGEL, JOHN R	Director	ストックオプション	購入	5,300	$0.00
2022-06-15	SULIMAN, SHEHNAAZ	Director	普通株式	購入	2,120	$0.00
2022-06-15	POPOVITS, KIMBERLY J	Director	ストックオプション	購入	5,300	$0.00
2022-06-15	MAMMEN, MATHAI	Director	ストックオプション	購入	5,300	$0.00
2022-06-15	KOSARAJU, SRIDHAR	Director	普通株式	購入	2,120	$0.00
2022-06-15	KOSARAJU, SRIDHAR	Director	ストックオプション	購入	5,300	$0.00
2022-06-15	ROBERTS, BRYAN E	Director	普通株式	購入	2,120	$0.00
2022-06-15	ROBERTS, BRYAN E	Director	ストックオプション	購入	5,300	$0.00
2022-06-15	POPOVITS, KIMBERLY J	Director	普通株式	購入	2,120	$0.00
2022-06-02	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	1,651	$0.00
2022-05-23	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	967	$48.76
2022-05-23	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	1,264	$48.76
2022-05-23	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	2,656	$48.76
2022-05-23	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	286	$48.76
2022-05-16	KOSARAJU, SRIDHAR	Director	ストックオプション	売却	15,000	$0.00
2022-05-16	KOSARAJU, SRIDHAR	Director	普通株式	購入	15,000	$11.48
2022-05-13	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	購入	158	$40.49
2022-05-13	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	購入	158	$40.49
2022-03-22	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	購入	21,357	$0.00
2022-03-22	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	購入	28,476	$0.00
2022-03-22	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	購入	58,731	$0.00
2022-03-22	HINDSON, BENJAMIN J.	Director, See Remarks	ストックオプション	購入	71,189	$0.00
2022-03-22	SAXONOV, SERGE	Director, Chief Executive Officer	ストックオプション	購入	146,827	$0.00
2022-03-22	MCANEAR, JUSTIN J.	Chief Financial Officer	ストックオプション	購入	53,392	$0.00
2022-02-22	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	551	$78.60
2022-02-22	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	360	$78.59
2022-02-22	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	288	$78.60
2022-02-22	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	288	$78.60
2022-02-22	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	267,000	$0.00
2022-02-22	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	購入	133,500	$0.00
2022-02-15	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	17,000	$95.13
2022-02-15	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	ストックオプション	売却	17,000	$0.00
2022-02-15	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	購入	17,000	$1.16
2022-02-08	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	2,397	$91.04
2022-02-08	SAXONOV, SERGE	Director, Chief Executive Officer	ストックオプション	売却	3,038	$0.00
2022-02-08	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	900	$88.17
2022-02-08	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	購入	3,038	$11.48
2022-02-08	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	4,200	$89.19
2022-02-08	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	4,503	$90.30
2022-01-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	購入	17,000	$1.16
2022-01-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	1,017	$119.28
2022-01-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	6,195	$117.53
2022-01-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	1,100	$120.93
2022-01-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	3,200	$121.77
2022-01-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	100	$122.94
2022-01-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	100	$123.53
2022-01-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	3	$125.00
2022-01-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	ストックオプション	売却	17,000	$0.00
2022-01-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	100	$124.44
2022-01-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	5,185	$118.32
2022-01-04	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	500	$145.33
2022-01-04	SAXONOV, SERGE	Director, Chief Executive Officer	ストックオプション	売却	3,037	$0.00
2022-01-04	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	1,400	$144.78
2022-01-04	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	700	$143.11
2022-01-04	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	2,932	$141.72
2022-01-04	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	5,368	$140.96
2022-01-04	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	1,000	$138.86
2022-01-04	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	購入	3,037	$11.48
2022-01-04	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	3,100	$139.82
2022-01-03	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	3,583	$145.16
2022-01-03	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	500	$148.04
2022-01-03	HINDSON, BENJAMIN J.	Director, See Remarks	ストックオプション	売却	2,084	$0.00
2022-01-03	HINDSON, BENJAMIN J.	Director, See Remarks	ストックオプション	売却	39,582	$0.00
2022-01-03	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	1,334	$146.92
2022-01-03	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	600	$149.24
2022-01-03	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	2,000	$148.44
2022-01-03	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	2,906	$147.34
2022-01-03	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	17,396	$146.29
2022-01-03	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	16,464	$145.43
2022-01-03	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	2,300	$144.56
2022-01-03	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	購入	39,582	$74.58
2022-01-03	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	購入	2,084	$11.48
2022-01-03	MCANEAR, JUSTIN J.	Chief Financial Officer	ストックオプション	売却	10,000	$0.00
2022-01-03	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	500	$149.18
2022-01-03	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	購入	10,000	$5.04
2022-01-03	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	4,083	$145.96
2021-12-30	STUELPNAGEL, JOHN R	Director	普通株式	売却	3,218	$150.56
2021-12-30	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,782	$151.57
2021-12-30	KOSARAJU, SRIDHAR	Director	普通株式	売却	1,500	$150.38
2021-12-28	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	購入	53,952	$1.07
2021-12-28	HINDSON, BENJAMIN J.	Director, See Remarks	ストックオプション	売却	59,968	$0.00
2021-12-28	HINDSON, BENJAMIN J.	Director, See Remarks	ストックオプション	売却	53,952	$0.00
2021-12-28	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	購入	59,968	$1.20
2021-12-28	SAXONOV, SERGE	Director, Chief Executive Officer	ストックオプション	売却	56,363	$0.00
2021-12-28	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	購入	56,363	$1.20
2021-12-21	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	購入	49,910	$5.04
2021-12-21	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	購入	4,688	$1.20
2021-12-21	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	ストックオプション	売却	49,910	$0.00
2021-12-21	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	ストックオプション	売却	4,688	$0.00
2021-12-13	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	360	$0.00
2021-12-13	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	購入	17,000	$1.16
2021-12-13	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	1,565	$137.63
2021-12-13	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	3,235	$138.60
2021-12-13	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	9,599	$139.52
2021-12-13	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	1,701	$140.38
2021-12-13	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	800	$141.31
2021-12-13	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	100	$142.47
2021-12-13	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	ストックオプション	売却	17,000	$0.00
2021-12-07	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	672	$144.27
2021-12-07	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	571	$145.79
2021-12-07	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	754	$148.60
2021-12-07	SAXONOV, SERGE	Director, Chief Executive Officer	ストックオプション	売却	5,209	$0.00
2021-12-07	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	6,480	$147.05
2021-12-07	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	2,370	$147.96
2021-12-07	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	3,187	$143.36
2021-12-07	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	766	$142.40
2021-12-07	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	200	$138.86
2021-12-07	SAXONOV, SERGE	Director, Chief Executive Officer	ストックオプション	売却	3,037	$0.00
2021-12-07	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	購入	5,209	$5.04
2021-12-07	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	購入	3,037	$11.48
2021-12-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	1,302	$148.48
2021-12-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	100	$155.55
2021-12-01	MCANEAR, JUSTIN J.	Chief Financial Officer	ストックオプション	売却	10,000	$0.00
2021-12-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	購入	3,646	$5.04
2021-12-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	購入	35,232	$11.48
2021-12-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	購入	2,788	$74.58
2021-12-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	5,400	$145.66
2021-12-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	5,369	$146.53
2021-12-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	13,561	$147.65
2021-12-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	7,571	$148.42
2021-12-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	4,849	$149.46
2021-12-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	1,816	$150.66
2021-12-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	2,100	$151.46
2021-12-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	100	$152.25
2021-12-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	700	$153.91
2021-12-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	200	$155.55
2021-12-01	HINDSON, BENJAMIN J.	Director, See Remarks	ストックオプション	売却	3,646	$0.00
2021-12-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	購入	10,000	$5.04
2021-12-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	2,462	$145.54
2021-12-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	1,536	$146.49
2021-12-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	2,700	$147.62
2021-12-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	600	$149.41
2021-12-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	500	$150.71
2021-12-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	300	$151.31
2021-12-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	300	$151.80
2021-12-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	200	$153.86
2021-12-01	HINDSON, BENJAMIN J.	Director, See Remarks	ストックオプション	売却	35,232	$0.00
2021-12-01	HINDSON, BENJAMIN J.	Director, See Remarks	ストックオプション	売却	2,788	$0.00
2021-12-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	2,000	$150.51
2021-12-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,700	$151.10
2021-12-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,100	$151.79
2021-12-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	100	$154.02
2021-12-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	100	$155.55
2021-11-24	KOSARAJU, SRIDHAR	Director	普通株式	売却	1,500	$150.06
2021-11-22	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	772	$148.38
2021-11-22	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	281	$148.38
2021-11-22	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	281	$148.38
2021-11-22	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	351	$148.38
2021-11-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,048	$159.80
2021-11-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	3,052	$158.79
2021-11-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	800	$157.55
2021-11-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	100	$160.32
2021-11-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	100	$168.34
2021-11-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	購入	17,000	$1.16
2021-11-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	1,030	$163.10
2021-11-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	4,122	$164.18
2021-11-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	6,872	$164.87
2021-11-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	4,776	$165.89
2021-11-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	100	$167.27
2021-11-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	ストックオプション	売却	17,000	$0.00
2021-11-02	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	購入	5,208	$5.04
2021-11-02	SAXONOV, SERGE	Director, Chief Executive Officer	ストックオプション	売却	3,037	$0.00
2021-11-02	SAXONOV, SERGE	Director, Chief Executive Officer	ストックオプション	売却	5,208	$0.00
2021-11-02	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	5,946	$161.06
2021-11-02	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	3,241	$160.26
2021-11-02	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	5,613	$161.94
2021-11-02	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	200	$163.14
2021-11-02	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	購入	3,037	$11.48
2021-11-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	4,667	$163.34
2021-11-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	300	$160.48
2021-11-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	購入	10,000	$5.04
2021-11-01	HINDSON, BENJAMIN J.	Director, See Remarks	ストックオプション	売却	31,434	$0.00
2021-11-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	11,829	$163.15
2021-11-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	24,125	$163.87
2021-11-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	3,112	$164.75
2021-11-01	HINDSON, BENJAMIN J.	Director, See Remarks	ストックオプション	売却	10,232	$0.00
2021-11-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	200	$164.96
2021-11-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	4,333	$164.05
2021-11-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	300	$164.58
2021-11-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	500	$162.16
2021-11-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	2,906	$163.89
2021-11-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,494	$163.10
2021-11-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	100	$161.52
2021-11-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	100	$160.75
2021-11-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	100	$160.33
2021-11-01	MCANEAR, JUSTIN J.	Chief Financial Officer	ストックオプション	売却	10,000	$0.00
2021-11-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	購入	10,232	$5.04
2021-11-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	購入	31,434	$11.48
2021-11-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	1,100	$160.50
2021-11-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	1,500	$162.06
2021-10-25	KOSARAJU, SRIDHAR	Director	普通株式	売却	600	$165.14
2021-10-25	KOSARAJU, SRIDHAR	Director	普通株式	売却	100	$167.63
2021-10-25	KOSARAJU, SRIDHAR	Director	普通株式	売却	400	$166.60
2021-10-25	KOSARAJU, SRIDHAR	Director	普通株式	売却	100	$163.85
2021-10-25	KOSARAJU, SRIDHAR	Director	普通株式	売却	300	$168.68
2021-10-18	STUELPNAGEL, JOHN R	Director	普通株式	売却	300	$151.41
2021-10-18	STUELPNAGEL, JOHN R	Director	普通株式	売却	4,400	$150.51
2021-10-18	STUELPNAGEL, JOHN R	Director	普通株式	売却	300	$152.20
2021-10-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	ストックオプション	売却	17,000	$0.00
2021-10-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	購入	17,000	$1.16
2021-10-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	5,960	$156.49
2021-10-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	7,997	$157.40
2021-10-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	3,043	$158.63
2021-10-07	STUELPNAGEL, JOHN R	Director	普通株式	売却	5,000	$150.18
2021-10-05	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	購入	5,208	$5.04
2021-10-05	SAXONOV, SERGE	Director, Chief Executive Officer	ストックオプション	売却	3,460	$0.00
2021-10-05	SAXONOV, SERGE	Director, Chief Executive Officer	ストックオプション	売却	5,208	$0.00
2021-10-05	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	300	$146.12
2021-10-05	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	1,720	$145.42
2021-10-05	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	1,900	$144.40
2021-10-05	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	6,056	$143.40
2021-10-05	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	購入	3,460	$11.48
2021-10-05	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	5,024	$142.47
2021-10-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	634	$141.96
2021-10-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	2,500	$142.80
2021-10-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	5,666	$143.79
2021-10-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	購入	10,000	$5.04
2021-10-01	HINDSON, BENJAMIN J.	Director, See Remarks	ストックオプション	売却	41,666	$0.00
2021-10-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	2,500	$144.77
2021-10-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	21,469	$143.97
2021-10-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	13,297	$143.13
2021-10-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	4,400	$142.16
2021-10-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	購入	41,666	$5.04
2021-10-01	MCANEAR, JUSTIN J.	Chief Financial Officer	ストックオプション	売却	10,000	$0.00
2021-10-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	1,200	$144.57
2021-09-23	KOSARAJU, SRIDHAR	Director	普通株式	売却	400	$157.71
2021-09-23	KOSARAJU, SRIDHAR	Director	普通株式	売却	1,100	$159.52
2021-09-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	700	$154.45
2021-09-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,169	$157.75
2021-09-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,631	$156.72
2021-09-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,500	$155.69
2021-09-13	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	400	$172.40
2021-09-13	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	2,700	$174.14
2021-09-13	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	2,694	$175.17
2021-09-13	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	3,906	$176.19
2021-09-13	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	1,700	$177.21
2021-09-13	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	1,000	$178.24
2021-09-13	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	500	$178.90
2021-09-13	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	100	$181.24
2021-09-13	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	購入	17,000	$1.16
2021-09-13	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	2,300	$169.06
2021-09-13	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	100	$184.32
2021-09-13	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	ストックオプション	売却	17,000	$0.00
2021-09-13	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	1,300	$170.30
2021-09-13	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	300	$171.20
2021-09-07	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	1,200	$185.50
2021-09-07	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	購入	9,791	$11.48
2021-09-07	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	700	$184.49
2021-09-07	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	1,414	$188.51
2021-09-07	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	2,800	$189.81
2021-09-07	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	2,702	$186.74
2021-09-07	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	2,025	$187.45
2021-09-07	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	3,759	$190.44
2021-09-07	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	400	$191.13
2021-09-07	SAXONOV, SERGE	Director, Chief Executive Officer	ストックオプション	売却	5,209	$0.00
2021-09-07	SAXONOV, SERGE	Director, Chief Executive Officer	ストックオプション	売却	9,791	$0.00
2021-09-07	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	購入	5,209	$5.04
2021-09-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	1,049	$174.39
2021-09-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	300	$175.36
2021-09-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,000	$176.36
2021-09-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	2,300	$177.62
2021-09-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,104	$178.34
2021-09-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	296	$179.15
2021-09-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	購入	10,000	$5.04
2021-09-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	374	$174.87
2021-09-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	1,139	$175.95
2021-09-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	2,200	$177.00
2021-09-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	4,747	$177.87
2021-09-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	1,540	$178.80
2021-09-01	MCANEAR, JUSTIN J.	Chief Financial Officer	ストックオプション	売却	10,000	$0.00
2021-09-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	購入	41,666	$5.04
2021-09-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	2,728	$175.69
2021-09-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	7,530	$176.65
2021-09-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	21,145	$177.72
2021-09-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	8,586	$178.56
2021-09-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	628	$179.20
2021-09-01	HINDSON, BENJAMIN J.	Director, See Remarks	ストックオプション	売却	41,666	$0.00
2021-08-26	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	360	$0.00
2021-08-23	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	270	$161.85
2021-08-23	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	337	$161.85
2021-08-23	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	742	$161.85
2021-08-23	KOSARAJU, SRIDHAR	Director	普通株式	売却	100	$164.05
2021-08-23	KOSARAJU, SRIDHAR	Director	普通株式	売却	200	$157.72
2021-08-23	KOSARAJU, SRIDHAR	Director	普通株式	売却	100	$160.56
2021-08-23	KOSARAJU, SRIDHAR	Director	普通株式	売却	500	$162.27
2021-08-23	KOSARAJU, SRIDHAR	Director	普通株式	売却	600	$163.25
2021-08-23	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	270	$161.85
2021-08-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	300	$157.31
2021-08-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	2,790	$159.93
2021-08-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	600	$160.56
2021-08-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,310	$158.84
2021-08-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	800	$161.84
2021-08-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	3,213	$159.13
2021-08-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	2,100	$157.19
2021-08-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	3,400	$160.00
2021-08-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	購入	17,000	$1.16
2021-08-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	5,087	$161.28
2021-08-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	ストックオプション	売却	17,000	$0.00
2021-08-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	2,400	$158.07
2021-08-03	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	7,946	$178.47
2021-08-03	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	購入	9,792	$11.48
2021-08-03	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	1,700	$176.52
2021-08-03	SAXONOV, SERGE	Director, Chief Executive Officer	ストックオプション	売却	5,208	$0.00
2021-08-03	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	904	$179.35
2021-08-03	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	4,450	$177.56
2021-08-03	SAXONOV, SERGE	Director, Chief Executive Officer	ストックオプション	売却	9,792	$0.00
2021-08-03	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	購入	5,208	$5.04
2021-08-02	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,140	$179.53
2021-08-02	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	1,800	$183.02
2021-08-02	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	5,200	$181.98
2021-08-02	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	700	$182.16
2021-08-02	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	2,302	$181.31
2021-08-02	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	2,298	$180.29
2021-08-02	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	2,202	$179.28
2021-08-02	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	1,698	$178.35
2021-08-02	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	購入	10,000	$5.04
2021-08-02	STUELPNAGEL, JOHN R	Director	普通株式	売却	100	$184.99
2021-08-02	STUELPNAGEL, JOHN R	Director	普通株式	売却	200	$183.90
2021-08-02	STUELPNAGEL, JOHN R	Director	普通株式	売却	400	$182.74
2021-08-02	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,100	$181.47
2021-08-02	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,100	$178.48
2021-08-02	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	500	$183.30
2021-08-02	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	300	$184.52
2021-08-02	MCANEAR, JUSTIN J.	Chief Financial Officer	ストックオプション	売却	10,000	$0.00
2021-08-02	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	購入	11,114	$1.20
2021-08-02	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	購入	30,552	$5.04
2021-08-02	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	5,903	$178.25
2021-08-02	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	8,050	$179.08
2021-08-02	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	10,713	$180.13
2021-08-02	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	8,800	$181.13
2021-08-02	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	800	$184.02
2021-08-02	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	400	$184.95
2021-08-02	HINDSON, BENJAMIN J.	Director, See Remarks	ストックオプション	売却	11,114	$0.00
2021-08-02	HINDSON, BENJAMIN J.	Director, See Remarks	ストックオプション	売却	30,552	$0.00
2021-08-02	STUELPNAGEL, JOHN R	Director	普通株式	売却	960	$180.33
2021-07-23	KOSARAJU, SRIDHAR	Director	普通株式	売却	459	$182.32
2021-07-23	KOSARAJU, SRIDHAR	Director	普通株式	売却	400	$183.07
2021-07-23	KOSARAJU, SRIDHAR	Director	普通株式	売却	400	$184.43
2021-07-23	KOSARAJU, SRIDHAR	Director	普通株式	売却	241	$185.96
2021-07-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	500	$168.57
2021-07-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	2,190	$170.83
2021-07-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	600	$171.44
2021-07-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,710	$169.75
2021-07-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	ストックオプション	売却	17,000	$0.00
2021-07-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	300	$191.60
2021-07-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	1,512	$188.32
2021-07-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	3,933	$187.31
2021-07-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	4,400	$185.87
2021-07-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	5,755	$185.07
2021-07-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	購入	17,000	$1.16
2021-07-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	500	$189.36
2021-07-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	600	$190.86
2021-07-06	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	2,000	$195.12
2021-07-06	SAXONOV, SERGE	Director, Chief Executive Officer	ストックオプション	売却	9,792	$0.00
2021-07-06	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	900	$190.12
2021-07-06	SAXONOV, SERGE	Director, Chief Executive Officer	ストックオプション	売却	5,208	$0.00
2021-07-06	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	1,700	$191.07
2021-07-06	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	4,017	$192.20
2021-07-06	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	3,027	$193.27
2021-07-06	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	2,756	$194.13
2021-07-06	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	500	$196.33
2021-07-06	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	100	$196.97
2021-07-06	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	購入	9,792	$11.48
2021-07-06	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	購入	5,208	$5.04
2021-07-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	2,872	$192.69
2021-07-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	2,800	$190.66
2021-07-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	2,700	$189.85
2021-07-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	購入	10,000	$5.04
2021-07-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	200	$196.00
2021-07-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	700	$194.81
2021-07-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	1,400	$193.76
2021-07-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	800	$192.95
2021-07-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	1,500	$191.73
2021-07-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,600	$189.94
2021-07-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	1,200	$195.60
2021-07-01	HINDSON, BENJAMIN J.	Director, See Remarks	ストックオプション	売却	41,666	$0.00
2021-07-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	700	$191.97
2021-07-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,300	$190.87
2021-07-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	700	$193.51
2021-07-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	500	$194.29
2021-07-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	7,202	$191.58
2021-07-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	12,845	$190.51
2021-07-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	9,058	$189.80
2021-07-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	購入	41,666	$1.20
2021-07-01	MCANEAR, JUSTIN J.	Chief Financial Officer	ストックオプション	売却	10,000	$0.00
2021-07-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	100	$195.82
2021-07-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	2,500	$194.58
2021-07-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	5,989	$193.63
2021-06-23	KOSARAJU, SRIDHAR	Director	普通株式	売却	400	$199.40
2021-06-23	KOSARAJU, SRIDHAR	Director	普通株式	売却	200	$197.26
2021-06-23	KOSARAJU, SRIDHAR	Director	普通株式	売却	500	$200.03
2021-06-23	KOSARAJU, SRIDHAR	Director	普通株式	売却	400	$201.74
2021-06-17	STUELPNAGEL, JOHN R	Director	普通株式	売却	100	$191.97
2021-06-17	STUELPNAGEL, JOHN R	Director	普通株式	売却	100	$190.97
2021-06-17	STUELPNAGEL, JOHN R	Director	普通株式	売却	500	$197.75
2021-06-17	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,700	$200.23
2021-06-17	STUELPNAGEL, JOHN R	Director	普通株式	売却	600	$199.30
2021-06-17	STUELPNAGEL, JOHN R	Director	普通株式	売却	100	$203.42
2021-06-17	STUELPNAGEL, JOHN R	Director	普通株式	売却	400	$196.75
2021-06-17	STUELPNAGEL, JOHN R	Director	普通株式	売却	300	$202.18
2021-06-17	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,000	$201.03
2021-06-17	STUELPNAGEL, JOHN R	Director	普通株式	売却	200	$195.30
2021-06-14	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	400	$193.64
2021-06-14	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	4,500	$192.12
2021-06-14	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	3,000	$191.16
2021-06-14	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	3,084	$190.01
2021-06-14	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	916	$189.03
2021-06-14	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	ストックオプション	売却	17,000	$0.00
2021-06-14	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	購入	17,000	$1.16
2021-06-14	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	5,100	$192.97
2021-06-11	MAMMEN, MATHAI	Director	普通株式	購入	625	$0.00
2021-06-11	KOSARAJU, SRIDHAR	Director	ストックオプション	購入	1,563	$0.00
2021-06-11	KOSARAJU, SRIDHAR	Director	普通株式	購入	625	$0.00
2021-06-11	POPOVITS, KIMBERLY J	Director	ストックオプション	購入	1,563	$0.00
2021-06-11	STUELPNAGEL, JOHN R	Director	ストックオプション	購入	1,563	$0.00
2021-06-11	STUELPNAGEL, JOHN R	Director	普通株式	購入	625	$0.00
2021-06-11	SULIMAN, SHEHNAAZ	Director	ストックオプション	購入	1,563	$0.00
2021-06-11	SULIMAN, SHEHNAAZ	Director	普通株式	購入	625	$0.00
2021-06-11	MAMMEN, MATHAI	Director	ストックオプション	購入	1,563	$0.00
2021-06-11	ROBERTS, BRYAN E	Director	普通株式	購入	625	$0.00
2021-06-11	ROBERTS, BRYAN E	Director	ストックオプション	購入	1,563	$0.00
2021-06-11	POPOVITS, KIMBERLY J	Director	普通株式	購入	625	$0.00
2021-06-08	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	2,361	$187.92
2021-06-08	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	600	$184.17
2021-06-08	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	5,239	$186.91
2021-06-08	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	購入	9,791	$11.48
2021-06-08	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	購入	5,209	$5.04
2021-06-08	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	4,600	$185.89
2021-06-08	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	2,200	$185.05
2021-06-08	SAXONOV, SERGE	Director, Chief Executive Officer	ストックオプション	売却	9,791	$0.00
2021-06-08	SAXONOV, SERGE	Director, Chief Executive Officer	ストックオプション	売却	5,209	$0.00
2021-06-04	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	200	$0.00
2021-06-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	3,350	$176.18
2021-06-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	13,326	$175.49
2021-06-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	1,000	$180.07
2021-06-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	3,473	$173.44
2021-06-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	3,792	$172.35
2021-06-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	8,292	$171.54
2021-06-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	購入	41,666	$1.20
2021-06-01	MCANEAR, JUSTIN J.	Chief Financial Officer	ストックオプション	売却	10,000	$0.00
2021-06-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	300	$180.02
2021-06-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	200	$179.21
2021-06-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	300	$178.07
2021-06-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	2,906	$175.77
2021-06-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	1,994	$174.93
2021-06-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	100	$176.72
2021-06-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	2,400	$175.77
2021-06-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,500	$174.80
2021-06-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	600	$173.72
2021-06-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	703	$172.56
2021-06-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,597	$171.58
2021-06-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	6,433	$174.47
2021-06-01	HINDSON, BENJAMIN J.	Director, See Remarks	ストックオプション	売却	41,666	$0.00
2021-06-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	300	$178.21
2021-06-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	2,500	$171.59
2021-06-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	800	$172.85
2021-06-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	1,000	$173.94
2021-06-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	300	$179.78
2021-06-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	購入	10,000	$5.04
2021-06-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	1,100	$179.33
2021-06-01	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	900	$177.99
2021-05-24	KOSARAJU, SRIDHAR	Director	普通株式	売却	400	$160.05
2021-05-24	KOSARAJU, SRIDHAR	Director	普通株式	売却	700	$161.15
2021-05-24	KOSARAJU, SRIDHAR	Director	普通株式	売却	300	$162.05
2021-05-24	KOSARAJU, SRIDHAR	Director	普通株式	売却	100	$163.04
2021-05-24	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	売却	771	$162.66
2021-05-24	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	281	$162.66
2021-05-24	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	売却	351	$162.66
2021-05-24	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	281	$162.66
2021-05-17	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,000	$142.48
2021-05-17	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,800	$141.36
2021-05-17	STUELPNAGEL, JOHN R	Director	普通株式	売却	2,600	$140.34
2021-05-17	STUELPNAGEL, JOHN R	Director	普通株式	売却	500	$139.59
2021-05-17	STUELPNAGEL, JOHN R	Director	普通株式	売却	600	$144.49
2021-05-17	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,000	$143.44
2021-05-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	ストックオプション	売却	17,000	$0.00
2021-05-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	5,123	$133.86
2021-05-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	1,200	$136.80
2021-05-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	100	$137.57
2021-05-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	2,702	$135.74
2021-05-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	7,875	$134.70
2021-05-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	購入	17,000	$1.16
2021-05-04	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	1,200	$182.14
2021-05-04	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	200	$188.75
2021-05-04	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	ストックオプション	売却	5,208	$0.00
2021-05-04	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	100	$186.75
2021-05-04	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	1,100	$185.91
2021-05-04	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	2,951	$185.04
2021-05-04	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	6,644	$184.20
2021-05-04	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	購入	9,792	$11.48
2021-05-04	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	購入	5,208	$5.04
2021-05-04	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	ストックオプション	売却	9,792	$0.00
2021-05-04	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	200	$179.71
2021-05-04	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	505	$180.94
2021-05-04	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	2,100	$183.06
2021-05-03	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	2,700	$191.77
2021-05-03	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	600	$189.57
2021-05-03	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	購入	10,000	$5.04
2021-05-03	STUELPNAGEL, JOHN R	Director	普通株式	売却	100	$198.09
2021-05-03	STUELPNAGEL, JOHN R	Director	普通株式	売却	100	$194.90
2021-05-03	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,320	$190.53
2021-05-03	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	20,100	$192.10
2021-05-03	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	5,361	$192.96
2021-05-03	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	800	$193.97
2021-05-03	STUELPNAGEL, JOHN R	Director	普通株式	売却	300	$193.84
2021-05-03	STUELPNAGEL, JOHN R	Director	普通株式	売却	2,200	$192.54
2021-05-03	STUELPNAGEL, JOHN R	Director	普通株式	売却	2,880	$191.83
2021-05-03	STUELPNAGEL, JOHN R	Director	普通株式	売却	600	$189.25
2021-05-03	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	購入	17,586	$1.20
2021-05-03	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	1,492	$189.07
2021-05-03	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	4,908	$190.19
2021-05-03	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	7,905	$191.07
2021-05-03	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	ストックオプション	売却	17,586	$0.00
2021-05-03	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	ストックオプション	売却	24,080	$0.00
2021-05-03	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	500	$194.88
2021-05-03	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	600	$197.91
2021-05-03	MCANEAR, JUSTIN J.	Chief Financial Officer	ストックオプション	売却	10,000	$0.00
2021-05-03	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	購入	24,080	$1.07
2021-05-03	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	100	$198.09
2021-05-03	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	200	$194.92
2021-05-03	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	794	$193.40
2021-05-03	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	3,706	$192.46
2021-05-03	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	1,900	$190.63
2021-04-30	ROBERTS, BRYAN E	Director	普通株式	売却	2,000,000	$0.00
2021-04-30	ROBERTS, BRYAN E	Director	普通株式	購入	2,000,000	$0.00
2021-04-23	KOSARAJU, SRIDHAR	Director	普通株式	売却	400	$193.11
2021-04-23	KOSARAJU, SRIDHAR	Director	普通株式	売却	300	$191.71
2021-04-23	KOSARAJU, SRIDHAR	Director	普通株式	売却	100	$194.74
2021-04-23	KOSARAJU, SRIDHAR	Director	普通株式	売却	600	$193.98
2021-04-23	KOSARAJU, SRIDHAR	Director	普通株式	売却	100	$190.05
2021-04-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,100	$189.97
2021-04-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,500	$190.70
2021-04-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	681	$191.85
2021-04-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	926	$192.85
2021-04-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,600	$193.86
2021-04-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,393	$194.83
2021-04-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	300	$195.74
2021-04-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	ストックオプション	売却	17,000	$0.00
2021-04-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	2,642	$181.84
2021-04-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	1,996	$187.10
2021-04-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	1,500	$185.14
2021-04-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	購入	17,000	$1.16
2021-04-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	1,100	$190.31
2021-04-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	1,302	$182.75
2021-04-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	1,400	$189.34
2021-04-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	2,398	$188.36
2021-04-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	600	$184.32
2021-04-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	907	$181.10
2021-04-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	2,855	$186.31
2021-04-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	300	$192.17
2021-04-06	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	100	$199.41
2021-04-06	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	購入	5,208	$5.04
2021-04-06	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	購入	9,792	$11.48
2021-04-06	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	800	$190.58
2021-04-06	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	200	$192.47
2021-04-06	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	1,900	$193.48
2021-04-06	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	1,826	$194.44
2021-04-06	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	1,097	$195.81
2021-04-06	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	5,428	$196.61
2021-04-06	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	2,849	$197.47
2021-04-06	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	800	$198.69
2021-04-06	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	ストックオプション	売却	5,208	$0.00
2021-04-06	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	ストックオプション	売却	9,792	$0.00
2021-04-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	3,487	$185.21
2021-04-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	700	$183.19
2021-04-01	MCANEAR, JUSTIN J.	Chief Financial Officer	ストックオプション	売却	10,000	$0.00
2021-04-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	1,800	$185.76
2021-04-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	3,795	$185.02
2021-04-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	2,272	$184.22
2021-04-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	600	$181.50
2021-04-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	1,900	$182.48
2021-04-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	6,686	$183.74
2021-04-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	200	$181.83
2021-04-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	800	$179.98
2021-04-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	300	$180.02
2021-04-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	16,748	$184.53
2021-04-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	14,632	$185.52
2021-04-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	300	$186.08
2021-04-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	ストックオプション	売却	41,666	$0.00
2021-04-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	3,205	$184.12
2021-04-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	700	$183.19
2021-04-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	200	$181.83
2021-04-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	購入	10,000	$5.04
2021-04-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	600	$185.90
2021-04-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	241	$180.27
2021-04-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	購入	41,666	$1.07
2021-03-23	KOSARAJU, SRIDHAR	Director	普通株式	売却	100	$175.71
2021-03-23	KOSARAJU, SRIDHAR	Director	普通株式	売却	200	$178.07
2021-03-23	KOSARAJU, SRIDHAR	Director	普通株式	売却	1,200	$173.96
2021-03-19	MCANEAR, JUSTIN J.	Chief Financial Officer	ストックオプション	購入	22,338	$0.00
2021-03-19	HINDSON, BENJAMIN J.	Director, See Remarks	普通株式	購入	11,169	$0.00
2021-03-19	HINDSON, BENJAMIN J.	Director, See Remarks	ストックオプション	購入	27,922	$0.00
2021-03-19	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	ストックオプション	購入	22,338	$0.00
2021-03-19	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	購入	8,935	$0.00
2021-03-19	SAXONOV, SERGE	Director, Chief Executive Officer	普通株式	購入	24,571	$0.00
2021-03-19	SAXONOV, SERGE	Director, Chief Executive Officer	ストックオプション	購入	61,428	$0.00
2021-03-19	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	購入	8,935	$0.00
2021-03-17	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,266	$172.29
2021-03-17	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,100	$169.27
2021-03-17	STUELPNAGEL, JOHN R	Director	普通株式	売却	813	$170.09
2021-03-17	STUELPNAGEL, JOHN R	Director	普通株式	売却	500	$171.27
2021-03-17	STUELPNAGEL, JOHN R	Director	普通株式	売却	601	$166.80
2021-03-17	STUELPNAGEL, JOHN R	Director	普通株式	売却	400	$174.50
2021-03-17	STUELPNAGEL, JOHN R	Director	普通株式	売却	700	$164.88
2021-03-17	STUELPNAGEL, JOHN R	Director	普通株式	売却	920	$167.98
2021-03-17	STUELPNAGEL, JOHN R	Director	普通株式	売却	800	$165.80
2021-03-17	STUELPNAGEL, JOHN R	Director	普通株式	売却	400	$173.28
2021-03-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	2,100	$154.52
2021-03-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	3,606	$156.52
2021-03-12	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	7,167	$159.40
2021-03-12	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	6,368	$158.64
2021-03-12	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	5,845	$157.48
2021-03-12	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	8,189	$156.45
2021-03-12	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	8,074	$155.54
2021-03-12	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	6,023	$154.56
2021-03-12	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	購入	5,302	$1.07
2021-03-12	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	購入	36,364	$0.88
2021-03-12	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	1,500	$154.37
2021-03-12	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	2,904	$155.35
2021-03-12	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	3,105	$156.35
2021-03-12	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	2,384	$157.42
2021-03-12	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	1,933	$158.49
2021-03-12	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	3,174	$159.35
2021-03-12	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	ストックオプション	売却	5,209	$0.00
2021-03-12	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	ストックオプション	売却	9,791	$0.00
2021-03-12	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	購入	5,209	$5.04
2021-03-12	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	購入	9,791	$11.48
2021-03-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	2,211	$157.70
2021-03-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	3,176	$158.85
2021-03-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	2,100	$159.51
2021-03-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	ストックオプション	売却	17,000	$0.00
2021-03-12	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	ストックオプション	売却	36,364	$0.00
2021-03-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	3,807	$155.54
2021-03-12	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	ストックオプション	売却	5,302	$0.00
2021-03-12	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	購入	17,000	$1.16
2021-03-10	MCANEAR, JUSTIN J.	Chief Financial Officer	ストックオプション	売却	9,583	$0.00
2021-03-10	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	購入	9,583	$11.48
2021-03-08	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	200	$148.08
2021-03-08	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	1,476	$146.88
2021-03-08	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	1,902	$145.90
2021-03-08	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	1,100	$145.03
2021-03-08	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	400	$142.49
2021-03-08	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	1,022	$141.25
2021-03-08	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	購入	10,000	$5.04
2021-03-08	MCANEAR, JUSTIN J.	Chief Financial Officer	ストックオプション	売却	10,000	$0.00
2021-03-08	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	1,200	$150.22
2021-03-08	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	1,100	$149.43
2021-03-08	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	400	$152.08
2021-03-08	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	300	$154.14
2021-03-08	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	100	$154.82
2021-03-08	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	800	$151.22
2021-03-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	700	$182.02
2021-03-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	600	$183.94
2021-03-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	400	$184.93
2021-03-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	2,883	$186.14
2021-03-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	200	$186.85
2021-03-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	900	$178.80
2021-03-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,317	$179.75
2021-03-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	500	$180.95
2021-02-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	451	$192.61
2021-02-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	2,683	$191.63
2021-02-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	600	$194.60
2021-02-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	800	$195.43
2021-02-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	633	$197.36
2021-02-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	233	$198.08
2021-02-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	300	$199.78
2021-02-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	400	$189.51
2021-02-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,400	$190.42
2021-02-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	購入	9,108	$5.04
2021-02-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,202	$177.23
2021-02-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	200	$178.98
2021-02-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	400	$174.15
2021-02-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	2,575	$175.22
2021-02-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	4,815	$175.92
2021-02-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	1,410	$176.99
2021-02-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	600	$177.99
2021-02-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	200	$178.98
2021-02-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	ストックオプション	売却	9,108	$0.00
2021-02-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	ストックオプション	売却	892	$0.00
2021-02-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	購入	10,000	$5.04
2021-02-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	600	$174.18
2021-02-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	5,213	$175.53
2021-02-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	400	$174.14
2021-02-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	3,094	$175.38
2021-02-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	2,304	$176.14
2021-02-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	300	$178.16
2021-02-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	購入	892	$11.48
2021-02-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	2,777	$176.51
2021-02-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	910	$177.50
2021-02-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	500	$178.49
2021-02-01	MCANEAR, JUSTIN J.	Chief Financial Officer	ストックオプション	売却	10,000	$0.00
2021-02-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	700	$173.79
2021-02-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	4,749	$174.90
2021-02-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	18,374	$175.74
2021-02-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	6,322	$176.65
2021-02-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	2,998	$177.68
2021-02-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	607	$179.01
2021-02-01	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	購入	17,000	$1.16
2021-02-01	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	746	$173.99
2021-02-01	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	4,003	$175.25
2021-02-01	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	8,451	$175.94
2021-02-01	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	2,700	$176.94
2021-02-01	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	900	$177.86
2021-02-01	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	200	$178.92
2021-02-01	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	ストックオプション	売却	17,000	$0.00
2021-01-25	KOSARAJU, SRIDHAR	Director	普通株式	購入	7,167	$0.00
2021-01-25	KOSARAJU, SRIDHAR	Director	普通株式	売却	7,167	$0.00
2021-01-19	STUELPNAGEL, JOHN R	Director	普通株式	売却	900	$181.49
2021-01-19	STUELPNAGEL, JOHN R	Director	普通株式	売却	376	$182.78
2021-01-19	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,608	$179.28
2021-01-19	STUELPNAGEL, JOHN R	Director	普通株式	売却	900	$176.57
2021-01-19	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,206	$180.27
2021-01-19	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,110	$178.31
2021-01-19	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,400	$175.79
2021-01-04	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	購入	10,000	$5.04
2021-01-04	STUELPNAGEL, JOHN R	Director	普通株式	売却	100	$141.61
2021-01-04	STUELPNAGEL, JOHN R	Director	普通株式	売却	900	$140.94
2021-01-04	STUELPNAGEL, JOHN R	Director	普通株式	売却	5,200	$139.88
2021-01-04	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,300	$138.91
2021-01-04	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	3,135	$140.74
2021-01-04	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	400	$141.77
2021-01-04	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	2,000	$139.08
2021-01-04	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	購入	10,000	$5.04
2021-01-04	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	ストックオプション	売却	10,000	$0.00
2021-01-04	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	200	$141.91
2021-01-04	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	1,523	$140.83
2021-01-04	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	6,277	$139.91
2021-01-04	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	2,000	$139.08
2021-01-04	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	購入	17,000	$1.16
2021-01-04	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	3,000	$138.97
2021-01-04	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	10,465	$139.89
2021-01-04	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	ストックオプション	売却	17,000	$0.00
2021-01-04	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	6,036	$139.91
2021-01-04	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	1,764	$140.78
2021-01-04	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	200	$141.91
2021-01-04	MCANEAR, JUSTIN J.	Chief Financial Officer	ストックオプション	売却	10,000	$0.00
2021-01-04	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	3,699	$138.78
2021-01-04	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	22,026	$139.83
2021-01-04	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	6,825	$140.62
2021-01-04	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	1,200	$141.58
2020-12-28	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	ストックオプション	売却	13,333	$0.00
2020-12-28	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	ストックオプション	売却	20,312	$0.00
2020-12-28	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	購入	13,333	$5.04
2020-12-28	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	購入	20,312	$1.20
2020-12-24	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	ストックオプション	売却	28,000	$0.00
2020-12-24	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	購入	8,636	$0.88
2020-12-24	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	購入	28,000	$1.20
2020-12-24	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	ストックオプション	売却	8,636	$0.00
2020-12-23	MCANEAR, JUSTIN J.	Chief Financial Officer	ストックオプション	売却	19,841	$0.00
2020-12-23	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	購入	19,841	$5.04
2020-12-22	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	購入	962	$1.20
2020-12-22	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	ストックオプション	売却	2,667	$0.00
2020-12-22	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	ストックオプション	売却	962	$0.00
2020-12-22	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	購入	2,667	$1.07
2020-12-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	2,200	$147.68
2020-12-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,101	$146.78
2020-12-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	3,098	$148.50
2020-12-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	801	$149.35
2020-12-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	300	$151.24
2020-12-14	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	15,000	$0.00
2020-12-14	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	購入	15,000	$0.00
2020-12-10	ROBERTS, BRYAN E	Director	普通株式	購入	93,487	$0.00
2020-12-10	VENROCK, ASSOCIATES VI, L.P.	10% Owner	普通株式	売却	268,692	$0.00
2020-12-10	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	104,960	$0.00
2020-12-10	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	購入	104,960	$0.00
2020-12-10	ROBERTS, BRYAN E	Director	普通株式	売却	268,692	$0.00
2020-12-08	ROBERTS, BRYAN E	Director	普通株式	購入	3,000,000	$0.00
2020-12-08	ROBERTS, BRYAN E	Director	普通株式	売却	3,000,000	$0.00
2020-12-08	ROBERTS, BRYAN E	Director	普通株式	売却	731,308	$0.00
2020-12-08	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	382	$0.00
2020-12-08	VENROCK, ASSOCIATES VI, L.P.	10% Owner	普通株式	購入	3,000,000	$0.00
2020-12-08	VENROCK, ASSOCIATES VI, L.P.	10% Owner	普通株式	売却	731,308	$0.00
2020-12-08	VENROCK, ASSOCIATES VI, L.P.	10% Owner	普通株式	売却	3,000,000	$0.00
2020-12-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	333	$153.84
2020-12-01	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	ストックオプション	売却	17,000	$0.00
2020-12-01	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	購入	17,000	$1.16
2020-12-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	ストックオプション	売却	33,750	$0.00
2020-12-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	2,835	$153.68
2020-12-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	4,700	$153.14
2020-12-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	4,619	$151.84
2020-12-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	11,113	$150.92
2020-12-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	10,483	$150.07
2020-12-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	購入	33,750	$0.88
2020-12-01	MCANEAR, JUSTIN J.	Chief Financial Officer	ストックオプション	売却	10,000	$0.00
2020-12-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	500	$153.79
2020-12-01	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	2,410	$152.96
2020-12-01	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	2,295	$151.68
2020-12-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	3,004	$150.01
2020-12-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	2,100	$150.15
2020-12-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	1,091	$151.92
2020-12-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	2,174	$153.26
2020-12-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	2,108	$153.21
2020-12-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	1,600	$151.80
2020-12-01	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	5,081	$150.02
2020-12-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	3,168	$150.94
2020-12-01	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	5,496	$150.87
2020-12-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	3,398	$151.02
2020-12-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	3,500	$150.99
2020-12-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	500	$151.68
2020-12-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	500	$152.88
2020-12-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	900	$153.54
2020-12-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	購入	6,250	$1.20
2020-12-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	購入	3,750	$5.04
2020-12-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	2,624	$150.03
2020-12-01	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	1,718	$153.58
2020-12-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	購入	10,000	$5.04
2020-12-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	ストックオプション	売却	3,750	$0.00
2020-12-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	ストックオプション	売却	6,250	$0.00
2020-11-17	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,100	$136.97
2020-11-17	STUELPNAGEL, JOHN R	Director	普通株式	売却	4,424	$136.19
2020-11-17	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,576	$135.41
2020-11-17	STUELPNAGEL, JOHN R	Director	普通株式	売却	400	$133.18
2020-11-03	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	購入	2,900	$5.04
2020-11-03	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	1,000	$136.54
2020-11-03	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	1,600	$137.57
2020-11-03	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	100	$138.73
2020-11-03	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	購入	2,924	$5.04
2020-11-03	MCANEAR, JUSTIN J.	Chief Financial Officer	ストックオプション	売却	2,900	$0.00
2020-11-03	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	200	$135.54
2020-11-03	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	1,000	$136.55
2020-11-03	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	1,524	$137.50
2020-11-03	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	200	$138.48
2020-11-03	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	ストックオプション	売却	2,924	$0.00
2020-11-03	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	ストックオプション	売却	6,496	$0.00
2020-11-03	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	200	$138.43
2020-11-03	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	購入	12,688	$0.88
2020-11-03	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	398	$135.52
2020-11-03	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	4,642	$136.62
2020-11-03	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	7,353	$137.57
2020-11-03	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	295	$138.49
2020-11-03	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	ストックオプション	売却	12,688	$0.00
2020-11-03	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	購入	6,496	$1.16
2020-11-03	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	200	$135.42
2020-11-03	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	2,198	$136.60
2020-11-03	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	3,898	$137.56
2020-11-03	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	200	$135.55
2020-11-02	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	1,500	$135.29
2020-11-02	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	1,200	$136.97
2020-11-02	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	800	$138.40
2020-11-02	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	400	$139.25
2020-11-02	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	4,376	$136.10
2020-11-02	MCANEAR, JUSTIN J.	Chief Financial Officer	ストックオプション	売却	7,100	$0.00
2020-11-02	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	500	$137.99
2020-11-02	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	400	$139.21
2020-11-02	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	ストックオプション	売却	10,504	$0.00
2020-11-02	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	購入	10,504	$1.16
2020-11-02	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	6,604	$136.06
2020-11-02	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	1,940	$136.98
2020-11-02	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	13,242	$136.11
2020-11-02	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	3,328	$135.36
2020-11-02	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	購入	21,062	$0.88
2020-11-02	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	500	$137.10
2020-11-02	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	購入	7,100	$5.04
2020-11-02	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	ストックオプション	売却	826	$0.00
2020-11-02	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	ストックオプション	売却	6,250	$0.00
2020-11-02	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	900	$138.54
2020-11-02	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	500	$137.10
2020-11-02	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	4,052	$136.13
2020-11-02	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	1,624	$135.45
2020-11-02	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	購入	826	$5.04
2020-11-02	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	1,146	$138.06
2020-11-02	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	1,406	$139.13
2020-11-02	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	購入	6,250	$1.20
2020-11-02	STUELPNAGEL, JOHN R	Director	普通株式	売却	500	$139.03
2020-11-02	STUELPNAGEL, JOHN R	Director	普通株式	売却	772	$137.47
2020-11-02	STUELPNAGEL, JOHN R	Director	普通株式	売却	3,900	$136.23
2020-11-02	STUELPNAGEL, JOHN R	Director	普通株式	売却	2,328	$135.62
2020-11-02	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	ストックオプション	売却	21,062	$0.00
2020-11-02	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	1,324	$135.40
2020-10-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	4,499	$163.99
2020-10-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	3,001	$164.66
2020-10-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	16,905	$125.47
2020-10-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	701	$124.21
2020-10-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	3,700	$125.51
2020-10-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	2,999	$125.99
2020-10-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	100	$126.88
2020-10-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	購入	6,250	$1.20
2020-10-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	購入	3,750	$5.04
2020-10-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	1,600	$124.35
2020-10-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	6,150	$125.54
2020-10-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	2,250	$126.08
2020-10-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	ストックオプション	売却	6,250	$0.00
2020-10-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	ストックオプション	売却	3,750	$0.00
2020-10-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	購入	10,000	$5.04
2020-10-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	1,300	$124.19
2020-10-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	5,612	$125.48
2020-10-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	2,988	$125.98
2020-10-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	100	$126.88
2020-10-01	MCANEAR, JUSTIN J.	Chief Financial Officer	ストックオプション	売却	10,000	$0.00
2020-10-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	購入	33,750	$0.88
2020-10-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	3,800	$124.26
2020-10-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	12,645	$125.98
2020-10-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	400	$126.88
2020-10-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	ストックオプション	売却	33,750	$0.00
2020-10-01	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	購入	17,000	$1.16
2020-10-01	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	2,500	$124.26
2020-10-01	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	10,725	$125.48
2020-10-01	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	3,475	$125.99
2020-10-01	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	300	$126.88
2020-10-01	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	ストックオプション	売却	17,000	$0.00
2020-09-18	ROBERTS, BRYAN E	Director	普通株式	売却	338,019	$0.00
2020-09-18	ROBERTS, BRYAN E	Director	普通株式	購入	121,804	$0.00
2020-09-18	VENROCK, ASSOCIATES VI, L.P.	10% Owner	普通株式	売却	338,019	$0.00
2020-09-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	813	$121.64
2020-09-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	2,265	$122.88
2020-09-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	700	$123.48
2020-09-16	ROBERTS, BRYAN E	Director	普通株式	売却	911,981	$0.00
2020-09-16	VENROCK, ASSOCIATES VI, L.P.	10% Owner	普通株式	売却	911,981	$0.00
2020-09-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	400	$119.67
2020-09-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	3,322	$120.62
2020-09-02	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	150	$114.10
2020-09-02	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	50	$114.89
2020-09-02	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	ストックオプション	売却	3,224	$0.00
2020-09-02	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	100	$114.90
2020-09-02	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	405	$114.10
2020-09-02	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	購入	3,224	$1.16
2020-09-02	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	700	$112.93
2020-09-02	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	2,953	$112.07
2020-09-02	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	1,900	$111.40
2020-09-02	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	購入	6,058	$0.88
2020-09-02	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	ストックオプション	売却	6,058	$0.00
2020-09-02	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	1,000	$111.33
2020-09-02	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	1,496	$112.32
2020-09-02	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	528	$113.18
2020-09-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	1,900	$112.91
2020-09-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	3,517	$113.91
2020-09-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	2,002	$112.96
2020-09-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,881	$114.88
2020-09-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	100	$115.46
2020-09-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	購入	2,640	$1.20
2020-09-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	購入	7,360	$5.04
2020-09-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	購入	14,000	$1.07
2020-09-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	1,700	$112.86
2020-09-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	215	$115.52
2020-09-01	MCANEAR, JUSTIN J.	Chief Financial Officer	ストックオプション	売却	10,000	$0.00
2020-09-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	ストックオプション	売却	27,692	$0.00
2020-09-01	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	ストックオプション	売却	13,776	$0.00
2020-09-01	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	2,600	$112.92
2020-09-01	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	5,887	$113.82
2020-09-01	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	500	$115.41
2020-09-01	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	4,789	$114.65
2020-09-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	1,648	$115.34
2020-09-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	10,049	$114.55
2020-09-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	12,595	$113.67
2020-09-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	3,400	$112.73
2020-09-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	購入	27,692	$0.88
2020-09-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	2,684	$114.78
2020-09-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	ストックオプション	売却	14,000	$0.00
2020-09-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	購入	10,000	$5.04
2020-09-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	5,201	$113.83
2020-09-01	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	購入	13,776	$1.16
2020-09-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	5,086	$113.82
2020-09-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	3,014	$114.74
2020-09-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	200	$115.53
2020-09-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	ストックオプション	売却	2,640	$0.00
2020-09-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	ストックオプション	売却	7,360	$0.00
2020-08-17	STUELPNAGEL, JOHN R	Director	普通株式	売却	800	$102.99
2020-08-17	STUELPNAGEL, JOHN R	Director	普通株式	売却	5,938	$104.78
2020-08-17	STUELPNAGEL, JOHN R	Director	普通株式	売却	762	$105.61
2020-08-03	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	購入	10,000	$5.04
2020-08-03	STUELPNAGEL, JOHN R	Director	普通株式	売却	4,668	$99.08
2020-08-03	STUELPNAGEL, JOHN R	Director	普通株式	売却	2,532	$99.62
2020-08-03	STUELPNAGEL, JOHN R	Director	普通株式	売却	300	$100.96
2020-08-03	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	3,100	$98.87
2020-08-03	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	6,100	$99.38
2020-08-03	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	700	$100.63
2020-08-03	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	100	$101.31
2020-08-03	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	ストックオプション	売却	10,000	$0.00
2020-08-03	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	購入	10,000	$5.04
2020-08-03	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	2,852	$98.85
2020-08-03	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	6,348	$99.39
2020-08-03	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	800	$100.76
2020-08-03	MCANEAR, JUSTIN J.	Chief Financial Officer	ストックオプション	売却	10,000	$0.00
2020-08-03	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	購入	33,750	$0.88
2020-08-03	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	5,996	$98.76
2020-08-03	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	25,054	$99.33
2020-08-03	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	2,100	$100.52
2020-08-03	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	600	$101.24
2020-08-03	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	ストックオプション	売却	33,750	$0.00
2020-08-03	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	購入	17,000	$1.16
2020-08-03	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	7,458	$98.94
2020-08-03	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	8,342	$99.47
2020-08-03	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	1,200	$100.72
2020-08-03	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	ストックオプション	売却	17,000	$0.00
2020-07-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	3,774	$88.52
2020-07-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	3,626	$89.17
2020-07-16	STUELPNAGEL, JOHN R	Director	普通株式	売却	100	$90.15
2020-07-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	5,121	$87.18
2020-07-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	4,779	$88.03
2020-07-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	100	$88.63
2020-07-01	MCANEAR, JUSTIN J.	Chief Financial Officer	ストックオプション	売却	10,000	$0.00
2020-07-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	購入	33,750	$0.88
2020-07-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	14,474	$87.11
2020-07-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	18,065	$87.92
2020-07-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	普通株式	売却	1,211	$88.67
2020-07-01	HINDSON, BENJAMIN J.	Director, See Remarks, 10% Owner	ストックオプション	売却	33,750	$0.00
2020-07-01	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	購入	17,000	$1.16
2020-07-01	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	7,600	$87.11
2020-07-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	300	$88.88
2020-07-01	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	500	$88.73
2020-07-01	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	ストックオプション	売却	17,000	$0.00
2020-07-01	CRUTCHFIELD, BRADFORD	Chief Commercial Officer	普通株式	売却	8,900	$87.94
2020-07-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	ストックオプション	売却	10,000	$0.00
2020-07-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	購入	10,000	$5.04
2020-07-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	4,500	$87.99
2020-07-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	5,200	$87.16
2020-07-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	購入	10,000	$5.04
2020-07-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	100	$89.08
2020-07-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	3,896	$87.99
2020-07-01	STUELPNAGEL, JOHN R	Director	普通株式	売却	3,504	$87.08
2020-06-17	STUELPNAGEL, JOHN R	Director	普通株式	売却	1,057	$90.13
2020-06-17	STUELPNAGEL, JOHN R	Director	普通株式	売却	2,648	$89.48
2020-06-17	STUELPNAGEL, JOHN R	Director	普通株式	売却	3,795	$88.63
2020-06-15	POPOVITS, KIMBERLY J	Director	ストックオプション	購入	4,432	$0.00
2020-06-15	ROBERTS, BRYAN E	Director	ストックオプション	購入	4,432	$0.00
2020-06-15	SULIMAN, SHEHNAAZ	Director	ストックオプション	購入	4,432	$0.00
2020-06-15	STUELPNAGEL, JOHN R	Director	ストックオプション	購入	4,432	$0.00
2020-06-15	KOSARAJU, SRIDHAR	Director	ストックオプション	購入	4,432	$0.00
2020-06-15	MAMMEN, MATHAI	Director	ストックオプション	購入	4,432	$0.00
2020-06-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	2,200	$81.27
2020-06-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	1,800	$81.85
2020-06-01	MCANEAR, JUSTIN J.	Chief Financial Officer	ストックオプション	売却	10,000	$0.00
2020-06-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	500	$81.97
2020-06-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	ストックオプション	売却	10,000	$0.00
2020-06-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	購入	10,000	$5.04
2020-06-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	購入	10,000	$5.04
2020-06-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	900	$77.09
2020-06-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	1,100	$77.17
2020-06-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	2,100	$78.11
2020-06-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	1,700	$79.35
2020-06-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	1,100	$80.14
2020-06-01	SAXONOV, SERGE	Director, Chief Executive Officer, 10% Owner	普通株式	売却	3,500	$81.51
2020-06-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	2,100	$78.00
2020-06-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	1,400	$79.08
2020-06-01	MCANEAR, JUSTIN J.	Chief Financial Officer	普通株式	売却	1,600	$80.02
2020-04-30	PALADIN, CAPITAL MANAGEMENT, LLC	10% Owner	普通株式	売却	1,000,000	$78.25
2020-04-21	PALADIN, CAPITAL MANAGEMENT, LLC	10% Owner	普通株式	売却	568	$74.48
2020-03-17	PALADIN, CAPITAL MANAGEMENT, LLC	10% Owner	普通株式	売却	1,527,241	$0.00
2020-03-16	PALADIN, CAPITAL MANAGEMENT, LLC	10% Owner	普通株式	売却	619,306	$0.00
2020-02-20	PALADIN, CAPITAL MANAGEMENT, LLC	10% Owner	普通株式	購入	8,675,167	$
2020-02-20	PALADIN, CAPITAL MANAGEMENT, LLC	10% Owner	普通株式	売却	8,675,167	$

売上・収益性

売上高（直近12ヶ月）

$64,282万ドル

一株あたり売上高（直近12ヶ月）

$5.15

売上総利益（直近12ヶ月）

$44,438万ドル

営業利益（EBITDA：減価償却前）

$-6,409万ドル

利益率

-6.77%

営業利益率（直近12ヶ月）

-9.42%

配当・収入

配当金額（1株あたり）

$None

配当利回り

支払日

None

権利落ち日

None

バリュエーション指標

株価収益率（PER）

None倍

実績PER

-倍

予想PER

208.33倍

株価収益成長率（PEG）

None

株価売上高倍率（直近12ヶ月）

4.388倍

株価純資産倍率 (PBR)

3.542倍

1株当たり純資産（BPS）

$6.24

企業価値倍率（EV）

EV/売上高倍率

3.705倍

EV/EBITDA倍率

609.29倍

投資リターン

総資産利益率（直近12ヶ月）

-6.4%

自己資本利益率（直近12ヶ月）

-5.78%

リターン分析

日数			リターン中央値	累積リターン	分散（バリアンス）	標準偏差	最大下落率	最大下落期間	SPYとの相関係数
15日間	-6.588%	5.1739%	-0.5217%	-14.3342%	0.0016438803257459377	0.04054479406466307	-17.8681%	6日	0.1340850957690358
30日間	-6.588%	7.1681%	0.9058%	1.9687%	0.0015199177224837239	0.03898612217807414	-17.8681%	6日	0.2760857402063551
90日間	-11.1762%	12.5636%	0.0%	-2.8846%	0.0018871805918177886	0.043441691861825414	-20.1817%	7日	0.04214826635702278

損益計算書

会計期末日

2025-12-31

報告通貨

USD

売上高・粗利益

売上高

$642,823,000

粗利益

$443,881,000

売上原価

売上コスト

$198,942,000

商品・サービス原価

$198,942,000

営業経費

販売管理費

$316,134,000

研究開発

$238,632,000

運営コスト

$554,766,000

減価償却

$None

減価償却・償却費

$None

営業利益・税引前指標

営業利益

-$110,885,000

営業利益EBIT

$None

償却前営業利益EBITA

-$110,885,000

税引前利益

-$39,907,000

利息・投資・その他営業外項目

純投資収益

$None

純金利収入

$20,048,000

利息収入

$20,048,000

金利コスト

利息・債務コスト

$None

非利息収益

$None

営業外収益（その他）

$None

税金関連

法人税等

$3,637,000

当期純・包括利益

継続事業純利益

-$43,544,000

純利益

-$43,544,000

税引後包括利益

$None

貸借対照表

会計期末日

2025-12-31

報告通貨

USD

総資産

$1,041,365,000

流動資産

現金及び現金同等物

$473,966,000

現金及び短期投資

$473,966,000

短期投資

$49,443,000

在庫資産

$56,341,000

流動売掛金（純額）

$82,493,000

その他流動資産

$22,208,000

流動資産合計

$684,451,000

固定資産

有形固定資産

$None

減価償却累計額（PPE）

$None

無形資産

$62,329,000

無形資産（のれん除く）

$62,329,000

のれん（無形資産）

$4,511,000

投資

$None

長期投資

$None

その他固定資産

$None

固定資産合計

$356,914,000

総負債

$245,039,000

流動負債

買掛金（短期）

$12,733,000

前受金

$None

流動債務

$None

短期借入金

$10,985,000

固定長期負債

$None

その他流動負債

$105,834,000

流動負債合計

$153,454,000

固定負債

リース債務

$84,361,000

長期債務

$None

長期債務（流動外）

$None

短期・長期借入金合計

$157,737,000

その他固定負債

$7,708,000

固定負債合計

$91,585,000

純資産

$796,326,000

自己株式（金庫株）

$None

利益剰余金

-$1,510,591,000

普通株式

$2,000

発行済株式数（普通株）

$124,749,885

キャッシュフロー計算書

会計期末日

2025-12-31

報告通貨

USD

損益計算・収益性

損益

$None

純利益

-$43,544,000

営業活動

営業キャッシュフロー

$136,050,000

営業活動による支払い

$None

営業活動によるキャッシュフロー

$None

営業活動に関連する負債の増減額

$None

営業活動に関連する資産の増減額

$None

売掛金の増減額

$None

在庫資産の増減額

$27,953,000

減価償却・減耗費・償却費

$43,816,000

投資活動

投資活動によるキャッシュフロー

-$13,438,000

設備投資

$5,935,000

財務活動

財務活動によるキャッシュフロー

$6,803,000

短期融資回収金

$None

自社株買い支出（普通株）

$None

自社株買い支出（優先株）

$None

自社株買い支出

$None

配当支払い（普通株）

$None

配当支払い（優先株）

$None

配当支払い

$None

資金調達（普通株）

$None

資金調達（優先株）

$None

資金調達（長期債・資本証券）

$None

自社株売却による収益

$None

自社株再取得による収益

$None

資金・為替照合

現金及び現金同等物の増減額

$None

為替レートの変動による増減額

$None

発行済株式数

広告パネル

スポンサー紹介

本物のネイティブ講師による
オンライン英会話DOJO

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TXG

10X ジェノミクス

$20.20

TXG - 会社概要

利益・成長性

アナリスト予想・評価

EPS（1株当たり純利益）

配当履歴

株式分割

インサイダーの売却・購入履歴

売上・収益性

配当・収入

バリュエーション指標

企業価値倍率（EV）

投資リターン

リターン分析

損益計算書

貸借対照表

キャッシュフロー計算書

発行済株式数

本物のネイティブ講師によるオンライン英会話DOJO

本物のネイティブ講師による
オンライン英会話DOJO